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Home About NIA National Advisory Council on Aging (NACA) September 2018 Director's Status Report
September 2018 Director's Status Report
Click on the links below to view sections of the September 2018 Director's Status Report:
Staff Changes and Honors
Institute-Sponsored Meetings, Workshops, and Conferences
Publications and Web Content
Relevant Notices and Initiatives Published in the NIH Guide
Status of FY 2018 Budget:
The President signed into law the Consolidated Appropriations Act 2018 on March 23, 2018 to keep the government operating through September 2018. The enacted bill provides NIA $2.574 billion, a $526 million increase over the FY 2017 level. This amount included an additional $414 million for Alzheimer's Disease research funding.
The President's Budget request for FY 2019 was presented to Congress in April 2018 and includes $1.988 billion for NIA, a $586 million decrease from the FY 2018 enacted level.
On August 23, 2018 the Senate passed the Department of Defense and Labor, Health and Human Services, and Education Appropriations Act, 2019. This bill includes $3.08 Billion for NIA. This includes an additional $425 million for Alzheimer's Disease and related dementias research. Both chambers have now passed the bill and are currently conferencing to address other differences between the House and Senate versions before it can be signed into law.
Legislation of Interest:
On May 24, 2018, Senator Roger Wicker (R-MS) introduced S. 2956, the Patients First Act of 2018. The bill, if enacted, would require the HHS Secretary to prioritize stem cell research with the greatest potential for near-term clinical benefit in human patients and would prohibit the creation of a human embryo for research purposes or the destruction of or discarding of, or risk of injury to, a living human embryo. It would also require the HHS Secretary, in consultation with the NIH Director, to issue final guidelines implementing this provision within 90 days of enactment. S. 2956 was referred to the Senate Committee on Health, Education, Labor, and Pensions.
On June 12, 2018, the House passed by voice vote, H.R. 5002, the Advancing Cutting Edge (ACE) Research Act. The bill, if enacted, would provide other transactions authority to the NIH Director for "high-impact cutting edge research that fosters scientific creativity and increases fundamental biological understanding leading to prevention, diagnosis, and treatment of diseases and disorders, or research urgently required to respond to a public health threat."
On June 27, 2018, the Energy and Commerce Committee Health Subcommittee voted to advance H.R. 1676, the Palliative Care and Hospice Education and Training Act, as amended. Of interest to NIH, the amended bill requires NIH to develop and implement a Trans-NIH strategy to expand and intensify national research programs in palliative care in order to address the quality of care and quality of life for patients with serious or life-threatening illnesses. Specifically mentioned illnesses include: cancer; heart, kidney, liver, lung, and infectious diseases; as well as neurodegenerative diseases such as dementia, Parkinson's disease, or amyotrophic lateral sclerosis. The bill also requires NIH to include information about research on palliative care in the NIH Triennial Report.
Hearings, Visits, and Other topics of interest:
On August 23, 2018, the Senate HELP committee held a hearing titled, "Prioritizing Cures: Science and Stewardship at the National Institutes of Health." NIH Director Francis Collins testified accompanied by NIAID Director Anthony Fauci, NIA Director Richard Hodes, NCI Director Ned Sharpless, NICHD Director Diana Bianchi.
Submitted by: Dawn Beraud, Ph.D., Public Health Analyst, National Institute on Aging
Dr. Sanoj K. Suneja has been appointed Deputy Director, Division of Extramural Activities. Dr. Suneja has been Acting Deputy Director, DEA since January 2017, also serving as NIA's Health Science and Data Specialist, responsible for Council Activities, Extramural Research Grants Referrals, New and Early Stage Investigator Policies & Targets and responsible for NIH/NIA Funding Meetings & Policies. Dr. Suneja received his Ph.D. degree in Biochemistry from Haryana Agricultural University, India before doing Post-Doctoral and Research Investigator trainings at University of Connecticut Health Center, Farmington, CT. He has scientific expertise in Biochemical Toxicology, Auditory Neuroscience & Plasticity, and now in all Aging related research grants as the NIA's Primary Referral Liaison.
The Division of Extramural Activities welcomes Rene Etcheberrigaray, M.D. from CSR, where he served as Deputy Director and previously as Director, Division of Neurosciences, Development and Aging. Dr. Etcheberrigaray joins DEA as Senior Advisor to the Director DEA and brings highly valued management skills and a strong depth of knowledge and commitment to NIH peer review. Dr. Etcheberrigaray obtained his M.D. from the University of Chile in 1987. He then came to NIH as a Fogarty International Center postdoctoral fellow, studying ion channel physiology and molecular neurobiology in an NINDS intramural lab. He continued there as a visiting associate and then a visiting scientist. Etcheberrigaray later moved to Georgetown University, where he started a laboratory that focused on potential therapeutic targets for Alzheimer's disease and the role of calcium regulation and amyloid processing in the pathogenesis of Alzheimer's. Before returning to NIH, Dr. Etcheberrigaray was the lab director and senior scientist at a biotechnology company in Rockville.
The Division of Extramural Activities (DEA) welcomes Shahrooz Vahedi, Ph.D. as NIA's Training Officer. As a member of both NIA's Fellowship Funding and BRAIN initiative committees, he manages, enhances, and evaluates all training and career development awards at NIA, which include Institutional NRSA T32, T35, and Individual F30, F31, and F32 Fellowship Training programs, as well as all K career development funding mechanisms. He is also the first point of contact for Loan Repayment Program (LRP) application, review, funding, and tracking at NIA. Shahrooz actively participates at NIA's Diversity Supplement committee and is a member of NIH 's Diversity Supplement Point of Contact committee, where he represents NIA to coordinate the conception, planning, implementation and evaluation of trans-NIH activities and initiatives to improve diversity in health-related research workforce. Before joining NIA, Dr. Vahedi was a Research Scientist at National Cancer Institute where he was studying the role P-glycoprotein in developing multidrug resistance
Kimberly Kramer has been a STEM-track Presidential Management Fellow in the Division of Extramural Activities for the last two years. We are pleased to announce that she has come aboard as a permanent full-time employee. Kim serves as NIA's Guide Liaison, working with staff at the NIA and the NIH Guide to develop and facilitate the publication of funding opportunity announcements. She also assists the Division in web editing and analysis of grant application performance. She is currently working with program staff to facilitate the conversion to a new system, Funding Opportunity Announcement Module (FOAM).
We are very pleased to welcome back to NIA/BSR Dr. John W.R. Phillips as Chief of the Population and Social Processes Branch. For the past two years Dr. Phillips served as Associate Commissioner for Research, Evaluation, and Statistics at the Social Security Administration.
Dr. Jeannette Johnson is retiring as Deputy Chief of the Scientific Review Branch (SRB). Dr. Johnson has been leading the NIA-N Committee for the last ten years and during the last year she has seen the career development award applications increase exponentially. In order to achieve review of this larger set in a judicious manner, she has successfully managed to bring in new reviewers with diversified backgrounds with varying expertise; Dr. Johnson has a knack for picking well qualified, hard-working employees. In addition, to hiring a well-qualified team, she's been organizing second stage review for P01s and developed many standardized forms for expediency. Dr. Johnson has a ten-year history of providing excellent service to the Scientific Review Branch and to the field of scientific peer review, the NIA couldn't be prouder of her dedication. Early on in her career in scientific review she worked with other Scientific Review Officers from across NIH to build and develop core competencies for Scientific Review Officers. In addition to maintaining her role as the Deputy Chief, she has also carried a full load of reviews and has been responsible for reviewing more applications in the SRB than any other Scientific Review Officer. She conducts her work with integrity and responsibility, has received numerous kudos from several council members, peer reviewers, and her colleagues at NIH. Even in her final days at NIA, she continued to provide stellar customer service in training new colleagues and projecting an air of calm, in a sea of applications as the new NIA review officer began to manage the new workload. We wish her the best in her retirement, and she will truly be missed!
Amanda DiBattista, Ph.D., is the newest Health Scientist Administrator (Program Officer) in the Neurobiology of Aging Branch in the Division of Neuroscience at NIA. Since joining the Division of Neuroscience as a Research Program Analyst in 2017, Dr. DiBattista led several projects on data analytics supporting initiatives across NIA and NIH. She serves as the QVR Ambassador for NIA, acting as the liaison with the NIH Office of Extramural Research for data reporting. Dr. DiBattista also built tools using data science to potentially identify NIH funding gaps and facilitate assignment of incoming grant applications. Dr. DiBattista earned her Ph.D. in Neuroscience from Georgetown University in 2016. Her dissertation research was supported in part by an NIH predoctoral fellowship (F31) and focused on understanding how the APOE4 gene increases the risk for Alzheimer's disease using molecular, cellular and behavioral approaches. Prior to coming to the NIA, she worked at an editorial services company researching and matching academic editors and reviewers with manuscripts submitted to the peer-reviewed journal PLOS ONE.
Cerise Elliott, Ph.D. was recently appointed as a Program Officer for the Dementias of Aging Branch of the Division of Neuroscience (DN). She has been a member of the DN staff since January 2008 and was most recent a Senior Research Program Analyst involved in analysis and evaluation of grants systems, and in supporting programmatic activities. She previously held positions at the NIH in the Office of Intramural Research and the Office of Extramural Research for the Office of the Director from 2004 to 2008 where she was the liaison with non-profit organizations, patient advocacy groups, drug industry and individuals to effectively and creatively disseminate NIH policies and programs to stakeholders. Dr. Elliott received her B.S. in Chemistry from Creighton University in Omaha, NE and her Ph.D. in Neuroscience from the University of Nebraska Medical Center also in Omaha, NE. Her scientific research focused on cell apoptosis controlled by peripheral T cells in multiple sclerosis. Her recent programmatic interests are creating new and effective scientific collaborations, facilitating successful mentoring relationships among grantees and providing effective evaluation of program development. Her portfolio includes AD Health Disparities, Research Recruitment and Retention and administrating the AD Center program.
Dr. Henriette van Praag, Investigator in the Laboratory of Neurosciences, accepted a position at the Florida International University in Miami, FL in June 2018. Dr. van Praag received her Ph.D. from the Tel-Aviv University in Israel in 1992. She started at the National Institute on Aging (NIA) in 2007 after serving as Research Associate and later a Staff Scientist in the Laboratory of Genetics at the Salk Institute in La Jolla, CA.
Matthew Sutterer, Ph.D., has joined the Division of Neuroscience as a Health Specialist in the Behavioral and Systems Neuroscience of Aging Branch. Dr. Sutterer received his Ph.D. in Neuroscience from the University of Iowa under Dr. Daniel Tranel. His dissertation focused on changes in brain networks related to emotion and decision-making behavior following brain damage (e.g., stroke) or surgical intervention (e.g., tumor resection, epilepsy surgery). He then joined the laboratory of Dr. Michelle Voss at University of Iowa as a postdoctoral fellow where he conducted research in cognitive neuroscience of healthy aging with a focus on plasticity of brain networks and connectivity. This past year, Dr. Sutterer was selected as a AAAS Science and Technology policy fellow and worked at the National Institute of Justice in the U.S. Department of Justice.
Dr. David Schlessinger retired from the NIA in April 2018 after six decades as a scientist, twenty of those years at the NIH. Dr. Schlessinger received his Ph.D. in Biochemistry from Harvard University in 1960. After that, he served in various capacities at the Washington University School of Medicine in St. Louis, MO, including Professor of Microbiology, Professor of Genetics, and Director of the RIKEN – Washington University Exchange Program. In 1997, Dr. Schlessinger became a Senior Investigator and the Chief of the Laboratory of Genetics at the NIA. He later stepped down from this role but remained Chief of the Human Genetics Section of the newly formed Laboratory of Genetics and Genomics. Dr. Schlessinger was named a NIH Distinguished Investigator in 2011 as a result of his exceptional achievements. Upon his retirement in April, Dr. Schlessinger was granted Scientist Emeritus status in order to continue his research. Perhaps one of Dr. Schlessinger's most notable scientific contributions is the SardiNIA project, which is a study of the genetic and epidemiological factors associated with age-related traits and diseases in the Sardinian founder population. This study has been referred to as the "gem" of the NIA's Intramural Research Program.
Dr. Tamara Harris retired in June 2018 after having served 27 years at the NIA. She received her M.D. in 1978 from the Albert Einstein College of Medicine, Bronx, NY, and her M.S. in Epidemiology in 1985 from the Harvard School of Public Health, Boston, MA. Shortly after, Dr. Harris joined the Centers for Disease Control at the National Center for Health Statistics as a Medical Service Fellow and was later promoted to Medical Officer (Research). In 1991, Dr. Harris transferred to the NIA as a Medical Officer (Research) under the Commissioned Corps, U.S. Public Health Service, in the Laboratory of Epidemiology, Demography, and Biometry, now the Laboratory of Epidemiology and Population Sciences (LEPS). She retired from the Corps with the rank of Captain in 2008 and was converted to a Title 38 Medical Officer (Research)/Senior Investigator in LEPS, where she remained until her retirement from the federal government in June. During her tenure, Dr. Harris served as Acting Laboratory co-Chief of LEPS (2012-2018). Following her retirement, she was appointed as a Special Volunteer within LEPS.
2018 NIH Alzheimer's Disease Research Summit - March 1 and May 24, 2018, Bethesda, MD.
The 2018 NIH Alzheimer's Disease Research Summit Part I was held on March 1, 2018, and Part II on May 24, 2018. Sponsored by the NIA and supported by the Foundation for the National Institutes of Health, the Summit was attended in-person by more than 400 people and remotely through live videocast by more than 3,500 people. More than 90 speakers presented data from NIH-funded research, and Dr. Francis Collins and Dr. Richard Hodes provided remarks. The Summit goal was to highlight the progress, to date, towards achieving the AD research implementation milestones set from the 2012 and the 2015 AD Summits. In addition, the discussions included an integrated multidisciplinary research agenda that would enable precision medicine for Alzheimer's disease. This Summit resulted in the development of new and refinement of existing Recommendations. These recommendations were also used in updating the AD/ADRD Research Implementation Milestones Database. For more information, contact Laurie Ryan or Suzana Petanceska.
Behavioral Economics and the Promotion of Health Among Aging Populations – NAS Keck Bldg., Washington, DC – June 4-5, 2018
This workshop explored the potential for extending research on interventions based on behavioral economics principles into older populations, with a focus on the development and testing of interventions that will generate longer-term benefits as well as improving our mechanistic understanding of interventions and how they are sensitive to aging. The workshop also explored ideas about what modifications might be required to make interventions "work" in middle-aged or older adults and continue to work over longer periods of time. For additional information contact Dr. Jonathan W. King.
GSIG SEMINAR, Dr. Scott Budinger's – June 6, 2018, Bethesda, MD
GR Scott Budinger is the Chief of Pulmonary and Critical Care in the Department of Medicine at Northwestern University, Feinberg School of Medicine and is the Ernest S Bazley Professor of Airway Diseases as well as a Professor of Medicine (Pulmonary and Critical Care) and Cell and Molecular Biology. He presented a seminar on aging lung as part of an ongoing series organized quarterly by the GeroScience Interest Group (GSIG). The GSIG was formed to enhance opportunities for discussion of the intersection between the biology of aging and the biology of disease and conditions that are of interest across NIH institutes and centers. It is focused on the intersection between the basic biology of aging and the biology of diseases and conditions of aging, but with a longer view towards translation.
(Contact(s): Dr. Ronald Kohanski, DAB, 301/496-6402)
Spring Meeting of the NAS Board on Behavioral, Cognitive and Sensory Sciences - NAS Keck Bldg., Washington, DC – June 7-8, 2018
This regular meeting of the board on Behavioral, Cognitive and Sensory Sciences included a half-day seminar on a topic selected by NIA/BSR: "Indirect Social Influences in Midlife and Older Age." For additional information contact Dr. Melissa Gerald.
NIA Workshop: Paradoxical Lucidity in Late-Stage Dementia – June 18-19, 2018, Bethesda, MD
Patients with late-stage dementia have been reported to exhibit unexpected episodes of relevant verbal communication. These episodes, referred to here as Paradoxical Lucidity (PL), are characterized by spontaneous meaningful communication in patients who are assumed to have lost coherent verbal capacity. PL may point to preservation of neural structures and functions that, if better understood, may lead to greater insights into the pathophysiology of Alzheimer's disease and related dementias. The goals of the workshop were to discuss the current state of knowledge about PL and to identify important research questions that may lead to greater understanding of PL and its implications for treatment of patients with Alzheimer's disease and related dementias. Workshop participants included investigators with expertise from several relevant research areas including dementia, geriatrics, cognitive assessment, neurophysiology, systems neuroscience, computational linguistics, caregiver research, and palliative and end-of-life care. Program staff from NIA, NINR, and other NIH IC's, were in attendance. NIA DGCG Contact: Basil Eldadah.
AGE-RELATED CHANGES IN OSTEOIMMUNOLOGY – June 21, 2018, Bethesda, MD
The role of the immune system in regulating bone differentiation and homeostasis, and how this tissue cross talk is affected by aging has been of interest to DAB and NIA. A decline in immune function with aging has been known for decades and many alterations in the function of both the adaptive and innate immune systems have been documented. The knowledge that immune cells are mobilized from bone marrow led to the demonstration that different types of immune cells interact with both osteoblasts and osteoclasts, and that these interactions can modulate bone homeostasis.
Five pilot awards ($125,000 Direct Cost/year) were issued by NIA in 2013 to examine the regulation of a variety of pathways involved in this aspect of integrative biology. The Division of Aging Biology held a workshop on June 21, 2018 in Bethesda, MD to discuss recent progress in our understanding of the role of aging in osteoimmunology. The five previously funded investigators presented their findings from aged animals. In addition, several other investigators working in the field were invited to discuss recent developments in the field. Discussion of gaps as well as newly identified opportunities in our understanding of the interactions between immune cells and bone will be addressed.
(Contact: Dr. Rebecca Fuldner, DAB, 301/402-7748, and Dr. John Williams, DAB, 301/496-6403)
Using Longitudinal Studies of Younger Cohorts for Aging Research – NAS Keck Bldg., Washington, DC – June 25-26, 2018
Demographic, economic, and institutional changes from across the life course may have important consequences for the forces that shape inequalities in later life between and among cohorts. At this meeting experts considered crucial issues in the use of longitudinal studies of younger cohorts, highlighting important directions for future research that are expected to have major influence on research on aging. For additional information contact Dr. Amelia Karraker.
Spring Meeting of the NAS Committee on Population – June 27-28, 2018, Washington, DC
This regular meeting of the Committee on Population included a half-day seminar on a topic selected by NIA/BSR: "Leveraging Existing Data for the Study of Consequences of Disasters for Older Adults."
For additional information contact Georgeanne Patmios.
Leveraging Rarely-Investigated Populations for Research on Behavioral and Social Processes in an Aging Context – NAS Keck Bldg. – July 2-3, 2018, Washington, DC
This meeting examined the potential value of examining individual variation and normative, age-related changes in behavioral, affective, cognitive, and social processes and the unique contributions that can be made in studies that are pursued in non-Western or small-scale societies. Discussions included poverty or resource scarcity and uncertainty; social/cultural norms and practices; and how these affect decision-making, emotional function, and social connectedness and health. For additional information contact Dr. Dana Plude.
Twelfth Annual Division of Aging Biology New Investigators Forum (DAB NIF) – July 9-10, 2018, Bethesda, MD
The purpose of the forum was to bring together new awardees (Principal Investigators who are new to funding by DAB) in the spring/summer of the year following their award, in order to allow NIA program staff to get acquainted with new PIs as well as to allow participants to network with each other. Following last year's success, the forum opened to a broad group of new investigators, including R01 and R56 recipients. To accommodate the large number of participants, each new PI presented a poster describing the planned research (or results to date). In addition to a keynote speaker, sessions included short "dating-style" presentations by grantees, as well as presentations by DAB staff and NIA leadership, on issues such as scope of the science supported by DAB, funding mechanisms, review issues and other related topics. The format also provided a significantly expanded opportunity for networking among the investigators and plenty of opportunities for interactions with NIA staff. The overriding goal of the meeting was to encourage continued success for the new PIs as well as encourage interactions and collaborations. (Contact(s): Dr. Manuel Moro, DAB, 301/480-1796)
Lipid Signaling in Stress and Aging –July 11, 2018, Bethesda, MD
The purpose of the workshop was to assess the current and emerging knowledge of lipid signaling in stress and during aging while discussing evolving technologies that could advance our understanding of these processes.
Lipids are hydrophobic small molecules that can function as hormones, intermediate signaling molecules, structural elements in biological membranes, and vehicles for energy storage. Disruption in either storage lipids (triglycerides) or circulating lipid-protein complexes (lipoprotein particles) has been associated with age-related conditions such as obesity and diabetes. Recently, molecular mechanisms linking lipids to lifespan have been explored. For example, lipidomics studies in human hint at an association between lipid composition and long life where higher ratios of monounsaturated (MUFA) to polyunsaturated (PUFA) fatty acids appear to favor longevity. Interestingly, a similar trend for higher MUFA: PUFA ratios is found in long-lived animals in model systems. Additional studies have revealed a critical role of fatty acid desaturases in controlling the level of MUFAs, supporting a link between fatty acid metabolism and aging. Although these studies suggest a pro-aging role of PUFAs, specific PUFAs such as ω-6 PUFAs have been found to activate autophagy and promote survival under nutrient deprivation. Consistently, increased expression of certain lipases that produce free fatty acids results in extended lifespan.
Lipid metabolism produces lipid signaling molecules. Current evidence suggests that lipid signaling pathways can modulate lifespan. For example, high levels of the lipid oleoylethanolamide (OEA) can extend lifespan in the worm by interacting with specific transcription factors. To deliver OEA to target tissues and organs, a lipid binding protein LBP-8 has been identified. Taken together, emerging evidence points to an important role of lipid metabolism and lipid signaling in influencing the process of aging. However, several central questions remain.
A workshop was proposed to address the following topics:
How are lipid signaling pathways altered during aging and physiological stress and what are the mechanisms?
How do epigenetic mechanisms control lipid signaling during aging?
How does lipid signaling contribute to different modes of longevity interventions, e.g. genetic vs environmental interventions?
(Contact: Dr. Yih-Woei Fridell, DAB, 301/496-7847, and Dr. Jose Velazquez, DAB, 301/496-6428)
NEURAL PROCESSES OF AFFECTIVE CHANGE IN AGING – August 2-3, 2018, Bethesda, MD
The NIA Division of Neuroscience and the Division of Behavioral and Social Research co-sponsored a workshop entitled "Neural Processes of Affective Change in Aging" on August 2-3, 2018 in Bethesda MD. The two-day workshop included 14 experts in affective and cognitive neuroscience who reviewed the current state of research in affective neuroscience and suggested future directions that might be facilitated by emerging theories and approaches from allied fields. The workshop proceedings and suggested next steps are being summarized in a report that is currently under development. For more information, contact Luci Roberts.
The Role of Sleep Deficiency and Sleep Disorders in Aging, Cognition and Neurodegeneration Workshop - August 20-21, 2018, Bethesda, MD
The NIA Division of Neuroscience, in conjunction with NHLBI and other ICs, co-hosted a workshop on "The Role of Sleep Deficiency and Sleep Disorders in Aging, Cognition and Neurodegeneration". This workshop showcased recent basic and clinical research advances to identify state-of-the-science, identify the gaps at the nexus of these fields, and highlight the collaborative opportunities needed to advance our understanding of the mechanisms linking sleep/circadian science and mild cognitive impairment associated with the risk of Alzheimer's disease. The participants included representatives from academia, industry and government. Recent research advances, gaps and opportunities identified will be outlined in in a report to be published. This report is currently under development. For more information, contact Miroslaw (Mack) Mackiewicz.
Optogenetics Investigators Meeting - August 23-24, 2018, Bethesda MD
The Optogenetics Investigators Meeting took place on August 23-24, 2018 in Bethesda, MD. This annual meeting provides a forum for investigators funded under RFA-AG-14-002 (Optogenetic Tools for the Study of Neural Systems in Aging and Alzheimer's Disease) to update attendees on their research progress, share ideas and troubleshoot problems, engage in face-to-face discussions and forge collaborations. Meeting attendees included the funded RFA investigators, a number of trainees supported by the program, and NIA staff, both extramural and intramural. For more information, contact Dr. Coryse St. Hillaire-Clarke.
Contributions of Artificial Intelligence to Research on Determinants and Modulation of Health Span and Life Span – August 29-30, 2018, Bethesda, MD
This workshop investigated the ways that artificial intelligence (AI) methods could contribute to understanding of the determinants of health span and life span. Research on determinants of longevity and health span poses a variety of methodological challenges. Longevity and health span involve a multiplicity of interacting contributory factors. The interactions of such factors also change with advancing age and are influenced by phenotypic changes over the life span. During the workshop, we explored how AI methods could address these complexities. Our interest was both in AI analyses that could be done on existing data, and on needs for new primary data that would allow productive application of AI methods for increased understanding of determinants of longevity and health span. Participants included experts from a variety of AI related fields, including: computer scientists, engineers, bioinformaticians, biologists and geriatricians. NIA DGCG Contact: Nalini Raghavachari
CELLULAR AND MOLECULAR AGING OF THE REPRODUCTIVE SYSTEM (September 10-11, 2018)
The Division of Aging Biology (DAB) held an exploratory workshop to discuss cellular and molecular mechanisms that preserve function in organs of the reproductive system that are critical to ensure healthy aging and prevent oncogenesis. The workshop critically reviewed current understanding of natural aging in the gonads and other reproductive tissues that affect health span and longevity, as well as examined current findings o the cross talk between these cells and their niche as a function of aging. The group provided recommendations to overcome identified potential targeted areas of study including mechanisms and their barriers that challenge the development of therapies to maintain healthy endocrine function and thwart oncogenesis.
The working group identified gaps in current understanding of the molecular and cellular mechanisms that regulate aging in the reproductive organs that facilitate health span and longevity. Metabolic, epigenetic, and circadian mechanisms of somatic and germ cell aging were evaluated with their interactions in the niche that regulate aging. Approaches to prevent, slow progression, or reverse stem cell and somatic cell senescence and negate oncogenesis in these tissues focusing on the ovaries, uterus, testis and prostate were reassessed. (Contact: Dr. Candace Kerr, DAB, 301/827-4474, and Dr. Rebecca Fuldner, DAB, 301/402-7748)
Enhancing the foundations for natural product clinical trials – September 13-14, 2018, Bethesda, MD
Other federal agencies and NIH ICs involved in the workshop include: The Food and Drug Administration, the U.S. Department of Agriculture, the National Cancer Institute, the National Center for Complementary and Integrative Health, the National Institute of Environmental Health Sciences, and the Office of Research on Women's Health.
The goal of the workshop is to enhance the progression of natural product research from foundational data (e.g., from preclinical and epidemiological research) towards reproducible data for actionable public health decision-making. The workshop brings together a broad range of expertise relevant to natural product clinical trials (NPCT) to discuss and develop recommendations for state-of-the-science rigor in obtaining, reporting, interpreting and assessing foundational data for NPCT, as well as for NPCT decision-making and design.
Workshop presentations will move between broad perspectives on rigorous approaches to experimental design, interpretation, and costs and benefits of different prioritization approaches, and specific, illustrative cases.
We anticipate the publication of the workshop proceedings. NIA DGCG Contact: Giovanna Zappala
The 29th Annual Nathan W. Shock Award Lecture – September 18, 2018 – Bethesda, MD
The Award was created in 1991 to honor Dr. Nathan Shock, the Father of American Gerontology, and was organized in an effort to increase collaborations within the aging research field. The 2018 awardee, Dr. Nathan LeBrasseur, will present a talk and meet with staff.
DECIPHERING THE GLYCOSYLATION CODE IN ALZHEIMER'S DISEASE – September 19-20, 2018, Bethesda MD
The NIA-sponsored glycosylation meeting is scheduled for September 19-20, 2018, to be held at the NIA Gateway office. The meeting will include leaders in the field to evaluate the current status of glycobiology in Alzheimer's Disease (AD) and to determine what areas of research will be needed to move the field of glycoscience in AD. In particular, the focus will be on understanding the importance of glycobiology in the area of biomarker discovery and early AD pathogenesis. For more information, contact Austin Yang, austin.yang@nih.gov.
The NIA and the NIH Comorbidity Scientific Interest Group Workshop are sponsoring a workshop entitled, "Measuring Multimorbidity: Matching the Instrument and the Purpose" – September 25-26, 2018, Bethesda, MD
The workshop is sponsored by the NIA and the NIH Comorbidity Scientific Interest Group and was designed to improve research that studies the role of co- and/or multimorbidity, by helping the field in selection of valid and reliable measurement tools. The purpose of this workshop is to a) identify the best available instruments for measuring co-/multimorbidity, and characterize their validity, reliability, and ease of use, as well as their statistical analysis and interpretation, b) propose a set of recommendations that would facilitate adoption of particular tools and methods for specific purposes (e.g., research vs. practice; observational studies; RCTs; large population-based samples; type of outcome (morbidity, mortality, healthcare utilization, quality of life, costs), and c) identify areas of research needs and gaps to improve measurement of multimorbidity. (NIA DGCG Contact: Marcel Salive)
American Society for Bone and Mineral Research (ASBMR) Working Group on Aging Symposia (September 30, 2018)
Annually there are 12 to 20 Working Groups that meet on the same night at the end of the regular scientific sessions. These Working Groups are not funded or sponsored by the ASBMR but are organized by people with similar topical interests. The level of attendance and the quality of these Working Group programs are wide ranging. There is only one Working Group devoted to the science of aging, while there are a wide range on things like Rare Diseases, certain Clinical problems etc. Historically the Working Group on Skeletal Aging has had only modest success but has always been financially strapped. In order to build attendance and improve the quality of the program we hope to get the Working Group a more reliable financial base to operate, both GCG and DAB have contributed some small funds. The NIA funds are used to pay the convention center facility fees and to help offset a speaker's hotel and travel. This year's sponsored speaker is Nathan LeBrasseur from Mayo, Rochester. Typically, we try to have one non-ASBMR speaker to address obvious areas of tissue cross talk of interest to ASBMR attendees. Each year's meeting combines clinical and basic science speakers in order to appeal to a broader spectrum of ASBMR attendees ().
This year, for the first time the Working Group is having a sit-down dinner which is being paid for via funds from the Working Group co-chairs institutions (Khosla at Mayo and Bonewald's Indiana Center for Musculoskeletal Biology). The goal of these working group programs is to raise awareness of NIA research and to present interesting science and generate wide ranging discussions on the topics raised in the presentations, including biomarkers in aging, age-related frailty and muscle dysfunction, and effects of aging on the osteocyte lacunocanalicular network. (Contact Dr. John Williams)
GSIG Seminar (October 24, 2018)
This seminar series is sponsored by the trans-NIH GeroScience Interest Group (GSIG). The GeroScience Interest Group (GSIG) was formed to enhance opportunities for discussion of the intersection between the biology of aging and the biology of disease and conditions that are of interest across ICs. It is focused on basic biology, but with a longer view towards translation. These four seminars will focus on the intersection between aging and diverse aging-related diseases and/or functional loss. Such topics are important to further the goals of the GSIG.
Specificity of molecular aggregates in AD and related neurodegeneration (November 27, 2018)
Aggregates consisting of amyloid beta (Ab, derived from the APP protein) or hyperphosphorylated Tau are considered the major pathological hallmarks of AD. Similarly, aggregates with different specific molecular identities are hallmarks for several other proteinopathies, and in fact, more than 50 such diseases are listed in Wikipedia. In addition to Ab, and Tau, well characterized proteinopathies affecting neurodegeneration include a-synuclein (Parkinson's), huntingtin (Huntington's), TDP-43 (Frontotemporal dementia) and many more. In addition to neurodegeneration, disease-causing proteinopathies exist in the periphery, examples of which include transthyretin (senile cardiac amyloidosis), amylin (type 2 diabetes), superoxide dismutase (amyotrophic lateral sclerosis,), crystallins (cataracts), cystic fibrosis transmembrane conductance regulator (cystic fibrosis) and many others. Pathology-causing aggregation of these proteins has been described in familial cases of each disease, usually driven by mutations in the protein or its processing that lead to a change in metastable forms of the protein in question. In contrast, sporadic forms of the same diseases also display molecularly similar aggregates, but in the absence of such direct genetic relationships. In these cases, the underlying common etiology appears to be aberrant proteostasis, which results in aggregation of different proteins in different tissues. To explore this possibility, researchers working on varied proteinopathies will be convened, to discuss commonalities and potential collaborations and cross-talks. It is expected that this effort might lead to the development of early markers of potential risk of developing proteinopathies in general, though the specificity of the pathological manifestation will still require measurements in the tissue of interest, including tissues of the central nervous system.
(Contact(s): Dr. Felipe Sierra, DAB, 301/451-4515)
New Animal Models of Alzheimer Disease (November 28, 2018)
The purpose of this workshop is to assess the current status of suitable, animal models of neurodegenerative disease conditions, focusing primarily in Alzheimer disease (AD) and discuss potential, new, emerging and translational models that may not only replicate all pathological features of the human disease but also contribute to the development of novel anti-dementia drugs. AD is the most common cause of dementia, affecting more than 40 million people worldwide. Despite considerable investment and effort, the prevalence is expected to increase dramatically in the coming decades due to an increase in the aging population. Unfortunately, there is no animal model available that can mimic the cognitive, behavioral, biochemical and histopathological abnormalities observed in patients with AD. However, partial reproduction of dementia and AD neuropathologies and cognitive deficits have been achieved with pharmacological and genetic approaches utilizing mice, fish, flies and worms. Most of the animal models used to study AD rely on the use of transgenic mice carrying mutations associated with early onset familial forms of AD, although sporadic cases represent the clear majority. There is a translational gap in AD studies, with promising drugs developed in rodent models failing in AD patients in clinical trials. Further studies are needed to develop and characterize new models from animals with naturally developing aspects of cognitive decline and memory loss that better recapitulate human dementia. The identification, characterization and development of genetic and histological tools of these potential models should permit further advances in the study of aging-related dementias and AD. (Contact(s): Dr. Manuel Moro, DAB, 301/480-1796)
The Epidemiology of Aging Workshop – December 18, 2018 (BRC)
The goal of this workshop is to engage experts in the field to discuss how data already collected from longitudinal studies can be used to maximize the effectiveness of future clinical trials, as well as designing a new generation of epidemiological studies that can be directed to best accomplish this goal. The two primary focuses will be: 1) Investigating age-related biomarkers; and 2) Developing indexes of biological, phenotypic, and functional aging that can be applied to different populations and are sensitive to change, potentially capturing the effect of interventions aimed at slowing down the "rate of aging."
Major Reports:
Sustaining Momentum: NIH Takes Aim at Alzheimer's Disease & Related Dementias (NIH Bypass Budget Proposal for FY 2019)
Booklets, AgePages, Fact Sheets, DVDs:
Biomarkers for Dementia Detection and Diagnosis fact sheet (new)
Exercise & Physical Activity: Your Everyday Guide from the NIA (reprint)
Lewy Body Dementia: Information for Patients, Families, and Professionals (update/reprint)
What's On Your Plate? (reprint)
AgePages:
A Good Night's Sleep
Open Science, Big Data, and You: Working Together to Treat and Prevent Alzheimer's Disease and Related Dementias (FY 2020 bypass budget report)
Geroscience: The intersection of basic aging biology, chronic disease, and health
What Do We Know About Healthy Aging?
Heart Health and Aging
What Is a Heart Attack?
Heart Health Glossary
Alzheimer's Summit Features Research Advances, Recommendations (NIH Record)
Spanish articles translated and posted:
Planificación anticipada para los cuidados de salud (Advance Care Planning)
El dolor: usted puede obtener ayuda (Pain: You Can Get Help)
La diabetes en las personas mayores (Diabetes in Older People)
La presión arterial alta (High Blood Pressure)
Press Releases and Research Highlights
NIA posted and distributed the following press releases:
NIH expands program that conducts large-scale clinical trials in real-world settings (7/24/18)
Senolytic drugs reverse damage caused by senescent cells in mice (7/9/18)
NIH-funded scientists put socioeconomic data on the map (6/29/18)
Heat-related health dangers for older adults soar during the summer (6/27/18)
NIH-funded study finds new evidence that viruses may play a role in Alzheimer's disease (6/21/18)
NIH summit delivers recommendations to accelerate therapy development for Alzheimer's disease (5/25/18)
New biological research framework for Alzheimer's seeks to spur discovery (4/10/18)
NIA posted the following featured research:
Gene module is target-rich environment for Alzheimer's pathology, cognitive decline (7/23/18)
Secrets of the coupled clock behind the heart's natural pacemaker cells (7/3/18)
New tests aim to support improvements in care for those dealing with delirium (6/26/18)
Alzheimer's-related risk gene neutralized in human brain cells (6/12/18)
Genetic risk variants linked to Alzheimer's amyloid brain changes at different stages of disease (5/30/18)
@NIAGo4Life Twitter followers now total 8,377, with an additional 15,848 subscribing to a daily e-alert of tweets
@Alzheimers_NIH Twitter followers now total 9,307, with 14,474 daily e-alert subscribers
NIHAging Facebook has more than 9,126 followers; quarterly peak reach (approximately 7,428 people) on 7/16 for post promoting doctor-patient communication.
Sent a total of 46 emails from 4/1/2018-7/31/2018 to the following NIA GovDelivery email lists:
Go4Life Fitness Tips: 81,567 subscribers
Healthy Aging Highlights: 76,104 subscribers
Alzheimer's News & Announcements: 75,197 subscribers
NIA for Caregivers: 15,714 subscribers
MEETINGS AND EXHIBITS
NIA/VA meeting, June 2018 -- Drs. Richard Hodes, Marie Bernard, and various NIA staff met with VA staff to share programmatic updates. Meeting participants discussed joint interests and initiatives and provided status updates regarding several ongoing projects.
NINDS-ADRD stakeholder roundtable meeting, June 2018 -- Drs. Richard Hodes, Marie Bernard, and various NIA staff participated in a large stakeholder meeting hosted by NINDS. Various ADRD groups along with NINDS and NIA staff shared programmatic updates and discussed areas for increased collaboration.
Meeting with the Ambassador of Costa Rica to the United States, June 2018 -- Drs. Richard Hodes and Marie Bernard met with the Costa Rican Ambassador, Roman Macaya Hayes, to discuss aging research. During the meeting, Dr. Hodes and the Ambassador discussed research projects in the US and Costa Rica, respectively, and possible areas of collaboration.
Conferences and Exhibits
None noted
(For more information about NIA's conferences or exhibits, contact Jennifer Watson, Acting Director, OCPL, Ph. 301-496-1752. For more information about NIA's professional meetings, contact Dr. Melinda Kelley, Legislative Officer, Ph. 301-451-8835.)
NEW NOTICES AND INITIATIVES RELEVANT TO THE NATIONAL INSTITUTE ON AGING (NIA) For the May 2018 Council Meeting
For 'Notices' and 'Research Initiatives' with NIA's participation or interest please visit these two websites: Grants & Funding and NIH Funding Policies (Please look for 'Recent Changes in NIH Policy' on this web link).


Microsoft has long had trouble with the hardware of its otherwise (extremely) successful Xbox gaming consoles, from hard drive failures in the original Xbox to the now-infamous "Red Ring of Death" in its sophomore Xbox 360 to an easily broken disk drive in the new Xbox. But an easy and, dare we say, fun way to lessen the outrage of customers, aside from all the typical customer service and easy returns stuff, is to be funny. And it's in the error message that Microsoft has been setting itself apart from its competition.
One of those messages is going to provoke a chuckle, and maybe even an Instagram or a tweet. One of those is going to result in frustrated puzzlement and a shrug.
Websites have long played with fun 404 pages–that's the error page you get when you follow a bad link or type something incorrectly into the address bar. (We collected a few of our favorites up top there.) They're an easy way for a faceless, monolithic corporation to show a little spark of personality. And they are easier to toy with than hardware errors, for the simple reason that hardware errors sometimes block the device's ability to, you know, display a message, fun or not.
For Microsoft, the playful error message is a small, intricate example of the company's new philosophy, laid out in the innovation of Windows 8 and Windows Phone: this is a company that executes ideas from people, and not faceless algorithmic drones.


As you pass under the main entrance gateway at Gervasi Vineyard and make your way towards the vineyards, you will quickly find yourself asking "Is this really in Ohio?" he Tuscan inspired architecture, landscaping, and interior decoration all make it very easy for bridal parties and their guests to lose themselves in the environment and just enjoy the surroundings. The Pavilion near the lake provides an intimate space for the reception and the grounds provide many options for outdoor ceremony settings. The more recent addition of The VIllas on the other side of the lake provides top shelf overnight accommodations for bridal parties and their families and the new Crush House restaurant is a great after party location to finish out the night.


This is the rough draft of the intro for my upcoming OSR campaign.
Welcome to the wonderful world of Old School. We'll be playing "undecided" rules using some classic D&D modules and my usual improvisation . You'll have opportunities for exploration, combat, RP, dungeon crawling, hex crawls, city adventures and more. If things go well you'll even get to enjoy the old fashioned end game and tackle a few of the high level modules.
Starting PC's are inhabitants of the village/town of Dunmer. Its a mostly self sufficient farming and fishing village with a population of nearly 250 freemen, located on the river Argan. Dunmer is famous only for its excellent knife works and its blades, knives and dagger not swords are exported quite widely. Other than that its like hundred of other villages and small towns in the Middle Kingdom.
Every half century or so there Argan River has a serious flood usually mildly This years flood, a few years ahead of time was particularly severe. While the mess has been cleaned up and the King's Relief has been sent the village will be some time recovering.
Now is an ideal time to set out for adventure. Not only will this take the strain off the limited resources you might be able to have a shot at real wealth.
You and some zero level friends and companions have come across a map that is purported to show a nearby bandit treasure, so grab your gear, adventure awaits ….


text:
title: Boston 2015 W5
category: running
tags: [boston2015,2015]
date: 2015-02-22T12:17:20+00:00
published: True
---

Week 5 of the boston training plan that this schedule

{% highlight console %}
Mon: 45 mins easy + 6 x Hill Sprints
Tues: LT Workout 5x5 mins @ LT (160-164 HR) - 75 sec recovery. 12-15 min WU/WD
Wed:50 mins easy
Thurs: 60 mins easy + 5 x 80m strides
Fri: Rest
Sat: Marathon Specific Long Run - 8x2k @ Marathon HR (154-154). 1 km float recovery @ 7:30 per mile (Get HR to low 140's). 3k WU& WD. N.B One continous run
Sun:30 mins easy
{% endhighlight %}

And this is how it played out

{% highlight console %}
Mon: Rest
Tues: 12km in 58mins.
Weds: 5x5 mins @ LT (160-170 HR). The 5 segments resulted in about 1.5km covered, the paces were 3.21,3.19,3.29,3.34,3.35.
Thurs: AM 6km in 32mins. PM 10km in 45mins.
Fri. Core class, cycled in, rest.
Sat: 8x2k @ Marathon HR (150-160). Felt bad going into this one. The paces for the 8 segments were 3.46,3.53,3.53,4.03,3.57,4.12,4.11,4.33. The firt 5 seemed OK but totally died on the 6/7th and the 8th was stagger to the finish.
Sun: No run - head cold.
{% endhighlight %}

All in 70km for the week.

redpajama_set_name: RedPajamaGithub


text:
1492: Lost, Gained, and Ever Changing
Indigenous Peoples Day Blog Series (2 of 5) By Guest Blogger Jewel Touchin, Senior Archaeologist - Logan Simpson
Jewel in prehistoric canal
Did you know there are more than 560 federally recognized tribes in the United States and that 22 of those tribes are present within the state of Arizona? Did you know that within the Navajo Nation alone there are approximately 90 clans, each with their own stories describing their origins and evolution? Imagine how many Native American communities there once were in the Americas! I think the general public both in America and internationally don't realize that Native American cultures still exist today and when they actually are aware of our contemporary presence, the majority don't spend much time trying to contemplate the amount of change Native people have experienced since 1492. Native Americans have experienced an exponential amount of change in the centuries past and continue to experience change today. I think the general public isn't cognizant of Native American history because it's not discussed in classrooms across the country. It's not part of the average school curriculum and it's not explained in school textbooks. It should be discussed, learned, and cherished by everyone because ultimately it's a very rich history, a foundation that ultimately evolved into American history.
With regards to the topic of change, a very surficial example of the amount of change Native people have experienced can be seen when one considers population estimates in the City of Phoenix and compares that with population estimates in the year 1492. In 2015, the U.S. Census estimates that there were approximately 1.5 million people in the City of Phoenix. Take a moment to imagine the knowledge encapsulated in the city today amongst those 1.5 million individuals. Think of all the doctors, nurses, engineers, teachers, construction workers and laborers, musicians, seamstresses, physicists, chemists, botanists, farmers, biologists, astronomers, chefs, etc. The knowledge that's within the city today is monumental. It's frankly spectacular and irreplaceable!
Map of prehistoric canal system in Salt River Valley, Courtesy of Jerry Howard
Compare those U.S. Census figures with estimates of population in the Americas in 1492. Some scholars estimate there were approximately 100 million people here in 1492. So if we take those numbers and try to draw some correlations, we could say that comparatively speaking there were enough people here in 1492 to fill about 66 cities the size of Phoenix. Even if we use conservative estimates and cut that number in half, 33 cities the size of Phoenix is still an immense amount of people.
After 1492, there was a huge drop in Native American population due to disease, genocide, and other factors. Some scholars estimate that by the year 1650 there were approximately 6 million Native people in the Americas. So basically we go population-wise…from 66 (or 33 if we use conservative estimates) cities the size of Phoenix to 4 cities the size of Phoenix in that short timeframe of approximately 150 years. Four cities!! Imagine the amount of knowledge that would be lost today if we subtracted that many people. It is incredible when we think of things in those terms. That lost knowledge represents unfathomable change in Native American cultures and communities throughout the continents of North and South America.
Canal along south border of Pueblo Grande
We don't have to look far to see evidence of this knowledge. In Phoenix, we can literally look in our backyards to see the ingenious innovation that prehistoric Native Americans possessed here in the Salt and Gila River valleys. There is blatant evidence of prehistoric engineering and irrigation technology that surpassed systems worldwide. Some of these irrigation systems in fact continue to be used by our current utility companies to service our population today. THAT'S amazing to me. THAT'S something that should be in every history textbook in America.
Despite the changes that have occurred in the past centuries, there's still a vast amount of knowledge and enormous diversity among tribal communities today. It would be fantastic if the general public could realize that. It would be fantastic if the general public would see what is in front of them: strong, intelligent Native people who know the art of survival.
Jewel Touchin
Senior/Associate Archaeologist at Logan Simpson
Jewel Touchin was born and raised in St. Michaels, Arizona on the Navajo Nation. She is an enrolled member of the Navajo Nation and an Arizona State University (ASU) alumnus. Jewel began her ASU studies as an Aeronautical Engineering major, but after much introspection and discussion with family members regarding Navajo thoughts and beliefs about archaeology, she graduated with a degree in Anthropology. She began her career soon afterwards and currently has more than 23 years of professional experience as an archaeologist in the Southwest. Jewel has worked in various development sectors including transportation, utility infrastructure, and sustainable energy. She has worked with two tribal nations, two engineering firms, and is currently employed with an environmental firm in Tempe.
Labels: 1492, American Indian, archaeology, Arizona, canal, Hohokam, Indigenous Peoples Day, irrigation, Jewel Touchin, Native American, Phoenix, prehistory, Pueblo Grande Museum
Flare Elliot October 10, 2017 at 10:57 AM
Simply Spectacular! Concise, but informative on a grand scale. I moved to Phoenix several years ago from the East Coast and feel as if I have moved to another country...I am madly in love with the cultural energy and the dazzling revitalized downtown. I realize now that Native Americans have simply been 'written out' of our history..I can't even go into the Indian School exhibit at the Heard anymore...it is so painful...this is so beautifully written, please publish in a format that will reach more people.♥
coralie cole October 10, 2017 at 12:19 PM
Fascinating reading, and I would love to learn even more!

redpajama_set_name: RedPajamaCommonCrawl


text:
Gucci on a platter
Fine fashion dining
What Gucci Creative Director Alessandro Michele has brought to the House is something to be considered as a holistic approach to a complete lifestyle, revolving around a set of values and iconography unique to the fashion world. Boutique plus exhibit space Gucci Garden, his brainchild standing tall and glorious in the historic city of Florence, is a landmark showcasing the brand's taste for art and food.
In keeping with the spirit of creative collaboration that Gucci embraces, Gucci Garden's restaurant, Gucci Osteria da Massimo Bottura, helmed by internationally renowned chef Massimo Bottura, opened in January 2018 and just after just two years it has received its first Michelin Star for the 2020 Italian Michelin Guide. Bottura's dishes explore the deep roots of the Italian kitchen while making references to history, art and philosophy, true to the Gucci Garden attitude.
His famous three-Michelin star restaurant, Osteria Francescana, located in his hometown of Modena, was named number 1 on The World's 50 Best Restaurants List in 2016 and 2018. Here, he collaborates with chef de cuisine Karime López, a Spaniard who went to Paris to learn French and prepare for art college in France, and instead discovered the pastries and cuisine of the city, which inspired her to go to cooking school in Spain for three years. Together they created a menu that is reinvented each season and is inspired by the people they have both met and the experiences they have had on their travels. The foreign influences are then applied to Italian cuisine.
'This restaurant is a reminder that Florence has always been a centre of cultural exchange, particularly during the Renaissance,' says Bottura. To reinforce this idea, lines of a 15th-century carnival song (canto carnascialesco) by Lorenzo de' Medici – "Canzona of the seven planets", or "Canzona de' sette pianeti" – are written in gold letters around the tops of the walls of the Gucci Osteria da Massimo Bottura. As for what is served here? Just one look and you can tell you are experiencing art on the plate. We wouldn't expect anything less now, would we?
www.gucci.com
Lunch 12.30 – 15.00 / Last reservation: 15.00
Dinner 19.00 – 22.00 / Last reservation: 22.00
The Feed Luisa Goes Virtual
The Feed Rimowa
Betty Catroux exhibition
Gucci art book by Bruce Gilden
Naomi, queen of the catwalk
Enter Greece
Life Collage
Let's get lost
For the love of the Riviera
It's Not About Me
Fashion for humanity
For the love of Chaos
Harper's Bazaar exhibition
Aerin Lauder's Palm Beach
Versace Campaign
Jane Birkin exhibition
Musée Yves Saint Laurent
Oviparity, a surreal take on Gucci
The Art of Santiago Calatrava: God of form
JJ Martin exclusive interview
Tim Walker, Wonderful Things
Interview with Yolo Journal's Yolanda Edwards
Mystras' hidden gem
The legendary Tony Duquette
Mystical Mykonos
Belle Belvedere


SpringHill Suites by Marriott Pittsburgh Mt. Lebanon is rated 4.5 out of 5 by 375.
Rated 5 out of 5 by IV from Pleasant hotel in Pittsburgh Very nice and spacious rooms. Clean and tidy. Friendly and serviceminded staff. Highly recommended.
Rated 5 out of 5 by Sheri from MtLebanon Great hotel. Employees are very friendly and helpful. Great breakfast!
Rated 5 out of 5 by Prof from Visit to Mt. Lebanon This hotel is located downtown in Mt. Lebanon. It is very conveniently located but parking is a problem when you check-in. However parking is available for a small fee under the hotel. The work-out area is small and doesn't have any weights. The rooms are exceptionally well-designed and very convenient. The lobby area is nicely laid out - very open and spacious. The staff are courteous and friendly. The downtown area in Mt. Lebanon provides lots of restaurants and a nice area for walking. Excellent hotel!
Rated 5 out of 5 by TXTraveler from Great Property Great Value Friendly Staff The staff person met us at the curb with a luggage cart. The room was clean and fresh. We were walking distance from stores and restaurants.
Rated 5 out of 5 by RK from Weekend Stay - Great property Rooms were very clean and the staff was excellent!
Rated 5 out of 5 by Patrice from Excellent but Needs More Parking On Saturday night we had to squeeze our mid-size rental SUV into a compact car space. Nothing else was available.


Can I Buy Land on a Reservation for My Project?
Native lands cannot be bought and sold. They are owned by the federal government and held in trust for the different Native American tribes. Therefore, non-Native businesses that are looking to locate on a reservation must enter into a land lease or build-to-suit lease arrangement with the tribe.
Until recently, the Bureau of Indian Affairs (BIA) on behalf of the Secretary of Interior, had to approve all leases on reservations, but with the passing of the HEARTH Act in 2012, tribes were given the ability to control their own leases once a tribe applied and was approved.
Is Development Similar on All Reservations?
Each Native American tribe operates like its own country. Each has its own tribal government structure, sets its own tax policies, and has its own development process. On some reservations, for example, tribal members can possess individual parcels or allotted lands. What this means for business owners and developers is that if their project impacts any allotted lands, they have to get the individual owners to sign-off before a development project can proceed. The location itself may make it worth the wait, but it can add time and cost.
For instance, in the Salt River Pima Maricopa Indian Community (SRPMIC), much of the Community's property fronting the Loop 101 is allotted land. It is not unusual to have 150 (and often more) individual owners that have to agree to the lease terms. Consequently, a typical timeframe to secure a lease at SRPMIC will take about 18-24 months. On other reservations like the Ak-Chin Indian Community, there are no allotted lands. All reservation property belongs to the Tribe as a whole and its use is governed by the Tribal Council, which means a developer can start and complete projects much faster. When Ak-Chin committed to building its $50 million multi-tainment center, for example, it was designed and built in 14 months.
Isn't Ownership Preferable to Leasing?
Leasing on a reservation can have distinct advantages over ownership. First, you eliminate the large initial capital outlay for land purchase. Moreover, some tribes will roll your construction costs into a long-term lease so you can amortize your development costs over the duration of your lease. Instead of tying up a large portion of your operating capital that may or may not appreciate, you use your capital to get your company growing immediately.
Are there other advantages to locating on tribal lands?
Other benefits of tribal locations may include tribal employment incentives, tax exemptions, as well as savings on utilities and public safety, especially if these services are tribally-owned. Again, every tribe is unique, so ask about their tax policies. Your business may not only be qualified for tribal exemptions, but also State and federal incentives.
How do I allay the doubts of wary company executives?
It just goes to show with a little basic understanding, tribal locations can provide great opportunities for businesses.


Mary Beth lost her son Matthew May 19th, 2013 to Addiction. This story chronicles her journey through co-dependency from living with not just an addict, but an addicted loved one.
Many people affected by addiction are not addicts themselves. In fact, most people affected by addictions are the people closest to the user/abuser. Through Mary Beth's journey you can see the addiction full fledged. You can get a feel for her grieving. You can hear the death of her son through her eyes. And we find out how she develops her own personal recovery.
How do we deal with the ones closest to us struggling with addictions? How do we deal when we may be addicted to them ourselves?
Don't just keep Mary Beth in our prayers but have hope for all of those struggling with the same issue!
We thank Mary Beth for her compassionate honesty. We wish her well on her journey. We wish everyone else reading our love, too.
"On Mother's Day 1996 my nearly 11 year old son Matthew told me that he had thought about ending his life. This jolt colors everything that came after in my life and my son's. There is a thread of anxiety running through all my parenting until the day he died of an accidental overdose of fentanyl and alcohol almost exactly 17 years later. I was always afraid, afraid his thoughts would turn into reality. Fear is not a good place from which to parent.
His father and I had separated and divorced when Matt was 9. His dad had only sporadic contact with him. I was the primary parent. For better or worse I made the decisions and bear responsibility. His use of alcohol and drugs were established by the time he was 15 or 16. It took me a while to catch on. I didn't want to see it. Show me a mother who does.
The older he got the bigger the problems. He was arrested for the first time when he was 16 and there were many times after that. All either drug or alcohol related. I consulted doctors, counselors, special ed teachers, interventionists, addiction counselors. Matt lived two years over a 3 year period at a long term residential program for at risk young men. He attended two different IOP's. There were diagnosis of ADD, depression, bipolar disorder, substance use disorder.
And through it all was my anxiety, my fear that the worst would finally happen. I hovered, drove both of us a little batty. I could see how much he had to offer, how intelligent he was, how creative. I could see it but nothing I said or did could make him see it.
The story goes on. I could tell the details but almost anyone who has loved an addict knows them already. He was intent on destroying himself and I was intent on preventing that destruction. He no longer lived with me but I subsidized his living on his own to various degrees at different times. I paid for his phone, his health insurance, occasionally his rent, bought textbooks and so on. I paid for things with money I shouldn't have used and had no right to give. In my own way I was as sick as he was. Finally, in 2012 my family helped me see what I was doing and I began more serious work with AlAnon, making my first faltering steps toward my own recovery.
I backed off as best I could, cut off the money supply and stopped trying to get him follow my agenda. In the words of a friend, I "respected his choices" or more accurately I respected his right to make his own choices. What followed were months of chaos and misery. It was during this period that I received a tearful phone call from Matthew. He sounded broken, lonely. He said, "Mom I feel like you're my best friend. You're the only one who tells me the truth." I think it says more about Matt's ability to burn bridges than anything else. By the last year of his life Matt had lost most of his friends and virtually all of his personal possessions. He was alone and very lonely.
It took 11 days but we found a bed for him at an inpatient treatment center in a nearby city. He did well, graduated and moved to sober living where he had a series of slips or relapses over a couple of months. He was in and out of a local hospital. I kept a certain distance, there was just so much chaos. I was trying to do my step work and build some healthy boundaries but Matt's addiction was not making that easy. He wasn't building any real clean time and was easy picking for the dealer who lived across the back yard. Matt was given the fentanyl which in combination with alcohol killed him on May 19, 2013.
What's next for me? Learning to live without the physical presence in this world of my only child and learning how best to integrate the lessons I've been taught over the years. What seems to do me the most good is helping others, putting my experience to work, encouraging other families and letting them know they are not alone. The challenge is to do that in a healthy way, helping people without neglecting myself. Knowing I control nothing but my own reaction to the world.
Over the years, I have come to see addiction as a prison where the addicts and everyone who loves them are the prisoners. The bars and doors are no less real than those in any county jail. The difference is we hold the keys to our own cells. We use those keys and free ourselves by being brave enough to ask for help."
We thank Mary Beth for her courage to share her story with the world. God bless, Mary Beth. The insight Mary Beth's story provides is crucial in understanding the true disease of addiction. It takes a tremendous amount of strength for someone to share this amount of honesty with the World. We should all give Mary Beth that much more respect!


text:
The Abyssal Zone
By Sara Eliza Johnson
Sometimes it's seaweed in your throat you can't cough out / or an ink cloud expanding in your skull
The Georgian Military Road
By Lars Horn, Illustrations by Sergiy Maidukov
An Unexpected Pilgrimage
Of Difference and Distinction
English is a treasure trove of words, each with a precise meaning. It is also a source of confusion and frustration, since so many of those words have subtle connotations and refuse to stand still.
ars poetica, 2019
By Airea D. Matthews
a woman who doesn't read many poems asks is poetry meant to be
Mostly Hamburg: '72
By Colin Channer
Confusion is the foreigner's advantage. Natives
tamp the nuance in their sounds. Stranger
seeking refuge pockets vowels, picks gesture,
learns body, gets caught up on the cobble
To Give Saying Its Shadow
By Ryan Ruby
On June 28, 1942, Victor Klemperer wrote in his diary, "Even if I hated Germany, I would not thereby become un-German, I could not tear what was German out of me." A Protestant convert of Jewish parentage, Klemperer had been forced out of his position as a professor of Romance languages at the Technical University of Dresden following the Nazi "dejudification" of the civil service. His car had been confiscated; his cat, euthanized; his house, "Aryanized." He and his wife, Eva, were forced to move into a Jews' House, where they roomed with a number of other families, all of whom were subject to constant surveillance and harassment by the Gestapo. He performed forced labor in a segregated factory, and lived on the brink of starvation.
The Hafgufa
By Patrick Barrett, Illustrations by Michael Byers
The Hafgufa is a giant fish or whale said in Old Norse writings to roam the seas.
In the Konungs Skuggsjá, a book of tactics and morality written by King Håkon Håkonsson for his young son, the king is loath to describe the creature—for no one, he says, will believe him without seeing it first with his own two eyes. As for him, he fears it, "for it is a massive fish, that looks more like an island than a living thing."
What Are Words
By Jill Bialosky
What are words when they meet the action
of what they attempt to modify?
By Claire Schwartz, Illustrations by Denise Nestor
Claire Schwartz: According to the poet Marie Howe, who studied with Joseph Brodsky at Columbia, Brodsky said: "You Americans are so naïve. You think evil is going to come into your houses wearing big black boots. It doesn't come like that. Look at the language. It begins in the language." You've written about the relationship between language and the social imagination—in particular, about the ways that totalitarian regimes in Russia and, more recently, the current government in the United States, have eroded public speech. Would you describe what you mean by that and how you see language functioning in public space right now?
Masha Gessen: For totalitarian regimes, language is an instrument of subjugation. It's a way of controlling both behavior and thought. Attempting to ensure that words mean what the regime says they mean is a way of undermining people's ability to inhabit a shared reality outside of what the regime says reality is. There are all sorts of tricks the regime performs along the way—such as using a word to mean its opposite, or almost its opposite.
By Deborah Eisenberg, Illustrations by Nicole Rifkin
Thundering down, a cataract from a high plateau, raising billows of dust, manes, tails, whinnies rippling like banners, a glamorous species, captive yes, but not entirely subdued, they—oh, no, a fellow in that ridiculous getup pops up from behind a rock and pulls out a—bink! That's enough, goodbye stupid old show, time for a cup of tea. Pulls out—bang, bang, bang. Yes, sensible Cordis decides, not a drink, time for a nice cup of tea.
The dog, a parting so-called gift from unfortunate Mrs. Munderson, peers at the blank screen, baffled, then paws at Cordis. Moppet is not glamorous, except in the most trivial sense; Moppet is cute. What does Moppet want? A treat? A tickle? A furlough?


A fascinating portion of this week's Republican debate centered around the issue of Syria, U.S. intervention, defeating ISIS, and even Russia. And what was said ran the gamut from we shouldn't get involved to we should go to war with Russia.
The Syrian free army that Bush mentioned there? Well, it is the FSA or the Free Syrian Army, and it doesn't exist anymore. As for so called moderate trained rebels in Syria that Bush wants to protect, that program was an utter failure.
And then the conversation turned to stopping Russia from fighting ISIS in Syria. Ben Carson indicated that what we should be doing in Syria isn't as much about stopping ISIS as it is about stopping Russia.
And there you had the other side. Trump asking the question, why wouldn't we allow Russia to fight ISIS, to use their weapons, their soldiers, their money to push ISIS out of Syria? And by the way, they are winning.
Assisted by Russian air strikes, Syrian President Bashar al-Assad's army broke an ISIS siege at a key airbase in Aleppo province on Tuesday that had been ongoing since 2013, liberating nearly 1,000 troops and lending credence to the idea that Putin's air strikes have tipped the scale against ISIS in Syria.
So what you need to know is that U.S. foreign policy in Syria has become so convoluted that the majority of the people who claim that they want to lead it don't understand it.
If that sounds insane to you, that's because it is.


Kids can collect all four Boxy Girls: Willa, Nomi, Brooklyn, and Riley. Each doll comes with four shipping boxes that kids can open to reveal fashion surprises, including clothes, bags, makeup, jewelry, and more.
I think their pupils will freak my daughter out!
I think that my grand-daughter would just love them.
What do you think about BOXY GIRLS?


Anna Webster works as a consultant landscape architect for Optimised Environments Ltd (OPEN) and has previously worked as a consultant to Lovejoy and AECOM Design + Planning (formerly EDAW).
Anna has been involved in a wide range of projects, with a focus on the landscape and visual assessment of various types of development, ranging from large scale wind energy development to small-scale hydro-electric schemes. Over the past 12 years, Anna has been involved in feasibility studies and the landscape and visual assessment of over 25 windfarms in Scotland, England and Northern Ireland. Anna has also been involved in the landscape and visual assessment and site appraisal of housing, opencast coal mines, a quarry, a waste-to-energy station, radar equipment, and business and retail development.
As well as landscape and visual assessment, Anna has been involved in the design and construction of a number of projects, including the hard and soft landscape at the new Edinburgh Royal Infirmary.


Explore games with Keyboard support tagged friends on itch.io · Upload your games with Keyboard support to itch.io to have them show up here.
Make platformer levels with your friends!
Made for the global game jam 2017.
Your the only one alive, will you manage to keep it that way?


text:
Create a perfect sex slave game
Added: Jadie Colson - Date: 23.07.2021 02:43 - Views: 10190 - Clicks: 9955
Slavery is the coercive and controlled use of another human. Contrary to the belief that the practice ended in the s, slavery still persists today. To be held in slavery is to be held in miserable conditions and have a form of power over you that denies you a life of freedom. For most people in Europe and North America slavery is not a visible problem, and one could think slavery is somehow less important, and less violent today than in the past. This is not the case.
The United Nations estimates that almost 21 million people are currently victims of slavery [25]. Central to our understanding of slavery and its related forms is that a person is recast, often without bodily integrity, as property that can be bought, sold, and accessed by others with more power, status, and money. Why begin an article on Sex Robots, and the rights of machines, with an introduction to human slavery? Because these themes are more interlinked than one might imagine, but perhaps not for the reasons you would think.
Today philosophers of technology, technologists, and Silicon Valley entrepreneurs are proposing that anthropomorphic robots should have rights. These elements posit that we are on the threshold of a new dawn of human-machine equivalence [13][32][46][55].
Moreover, some suggest that protecting anthropomorphic robots is a pathway to promoting human empathy, further confusing the issue of what is a machine [13]. Gunkel [55] furthers these perspectives by claiming that the exclusionary nature of human beings for example women or people of color demonstrates that the moral status of others is varied across time and space.
He writes. The vindication of the rights of machines, therefore, is not simply a matter of extending moral consideration to one more historically excluded other. There are even others in the field of robotics who claim that intimate attachments can be established between humans and machines in the form of robots [30]. In this article I ask how a discussion about artificial intelligence AI and robots became fused with a discussion of slavery, rights, and objects animate and inanimatewith these objects taking on the role of persons.
These themes are brought together through a discussion of sex robots. Anthropology, as the study of human cultures, explores how humans relate to each other, and how humans produce artefacts and engage with their material environments. The field of anthropology, along with co-connected disciplines of create a perfect sex slave game, myth, and religion, has a well-developed literature on the topics of anthropomorphism and animism [19][22].
Anthropomorphism is attributing humanlike characteristics to nonhuman animals and things, while animism is attributing life to the inanimate. While anthropomorphism and animism are topics associated with non-scientific and indigenous cultures, these anthropological themes, recurring through different cultures across space and time, are given new forms of expression in relation to artificial intelligence Al and robotics [43].
The desire to animate the inanimate, or attribute anthropomorphic qualities to nonhumans, is well documented. This is further echoed in texts that provide context for making the inanimate, animate. Capurro concludes that if the inanimate were animate, there would be no need for slaves. Let me introduce and emphasize the female as creator. Through the act of producing children, a woman is creating actual life, a point that is often absent from these genealogical surveys of creation through time.
I will pick up the mantel of these writers by introducing the myth of Pygmalion to discuss sex robots. Pygmalion was popularized by the Roman poet Ovid in his epic poem, Metamorphoses [39]. The statue comes to life. In readings of this story, Pygmalion represents another tale in this long lineage of stories about male animation of the inanimate.
But what I want to suggest is that Pygmalion is not a story about love, reciprocity, or empathy, but reflects a nonreciprocal encounter that underscores the imagination, promotion, and development of sex robots, inspired by power and coercion over women and girls. Men and male children are also prostituted, create a perfect sex slave game make up a small proportion of the buyers of sex, and fortunately not all men buy sex or consume pornography.
There is a strong movement now with males turning away from prostitution and pornography as they recognize the detrimental effects on their intimate relationships, an issue I believe will gain more ground over the next decade [3][18][35]. What is a sex robot? The artistic representation of the appearance of the human in objects is an historical accomplishment, with Renaissance artists able to produce realistic portraits of humans in two dimensions [5]. Since then, developments in the manufacturing of artificial materials, such as silicon, have allowed dolls to look more lifelike than their predecessors.
He wrote [20, p ]. With dolls, of course, we recall that children, in their early games, make no sharp distinction between the animate and the inanimate and that they are especially fond of treating their dolls as if they were alive. At present there is no working definition of a sex robot, and in reality there are really no sex robots. A concern about sex robots is not driven by the technology, but by ideas and practices that are drawn on to make and promote these mechanical objects. These robotic sex dolls mimic human appearance, may run voice activated programs, and have motors embedded in various parts of the robot body.
Sex robots are building on doll-like platforms popularized by the work of Matt McMullen, an artist and maker of RealDoll www. RealDolls are life sized dolls made with PVC skeletons with steel ts and silicone skin, but McMullen is also introducing technologies into these dolls such as voice activated programs. Also in the U. The making of these dolls does not stop at adults.
In Japan, child sex dolls resembling five year old girls are produced by company Trottla www. The dolls are modeled primarily on pornographic representations of women [27]. As I argued elsewhere [44]I did not make these easy comparisons between a sex robot and a prostituted person, this was done by sex robot advocates [30][31][53]. The Prize is a text-based challenge between an artificial chatbot and a human. Loebner has explained his views on the buying of sex, making comparisons between the buying of sex from a human body and the other commodities he buys:.
I pay for sex because that is the only way I can get sex. I am not ashamed of paying for sex. I pay for food. I pay for clothing. I pay for shelter. Why should I not also pay for sex? Paying for sex does not diminish the pleasure I derive from it Hugh Loebner cited in [29, p. At first sight it seems that sex robots objects are a preferable alternative to the violence regularly experienced by living prostituted women [17]. What does it matter if inanimate objects perform roles than humans once did? Here is another parallel between humans and robots:.
In my own work I argue that the buying of sex promotes a disruption to empathy, because the buyer of sex is not relating to the person as a subject but an object [44]. If the practices that inspire sex robots are not ethical for humans, they are not ethical for extending into machines.
Let us take a comparative look at industrialization and the automation of the workplace. There is no evidence at all that introducing more automation into the workforce reduces human inequalities. Jobs including bankers and lawyers are under threat [28]. Automation, machines, and robots do not in of themselves, reduce or end inequalities. In fact as wealthy elites primarily drive robotics, the purpose of these developments is to generate new forms of capital. Even paying taxes is avoided at all costs by elites through offshore s and creative marketing.
According to the international development charity Oxfam. What it means to be human is not constant over time and space, and we know from our cultural record that who is given the status of human depends very much on class, race, and gender [2][49]. All human beings are born free and equal in dignity and rights. They are endowed with reason and conscience and should act towards one another in a spirit of brotherhood [1]. Human rights codify what it means to be human, and offer political protections.
For example, Thomas Jefferson who penned and ed the Declaration of Independence also owned slaves, and women were not immediately emancipated.
Despite the problematic context of the U. Aristotle believed a slave was a living tool and a living piece of property and drew comparisons between an animate tool slave and an inanimate tool thing. It is worth citing at length what he thought about human tools:. So any piece of property can be regarded as a tool enabling a man to live, and his property is an assemblage of such tools; a slave is a sort of living piece of property; and like any other servant is a tool in charge of other tools.
It is important to understand that slaves are not machines. How can we be sure that slaves were not animate tools? Part of the answer lies in resistance, the other in coercion. But slaves did resist their captivity, epitomized in the famous of Spartacus, the rebel slave who led an uprising against the Roman Republic [58].
As described by Aristotle, slavery is a political system based on coercion and power. Slavery is about the politics of power exercised over others with less power. Here the human can be a thing, and things can be humanlike. While arguments for the rights of machines [55] and robots [13] appear a progressive step on the road to increasing the rights of others, the argument is based on a fundamentally distorted idea of the human as property, carried over into things.
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De, Use, and Effects of Sex Dolls and Sex Robots: Scoping Review


text:
Woody Allen's teen daughter defends him on Facebook
Editor, Yahoo Entertainment
Yahoo Celebrity May 29, 2018
Woody Allen at the premiere of "Wonder Wheel" in 2017. (Photo: Dimitrios Kambouris/Getty Images)
Woody Allen's daughter Bechet Dumaine Allen is shutting down accusations against her father.
The 19-year-old daughter of Allen and wife Soon-Yi Previn spoke out after Moses Farrow, whom Bechet referred to as her uncle, defended the filmmaker in an essay last week. In his piece, Moses alleged that his estranged sister, Dylan Farrow, lied about being molested by Allen as a child. Moses charged that his mother, Mia Farrow, was mentally and physically abusive to him and his siblings.
Bechet, who has largely avoided the spotlight, said she felt compelled to publicly take her father's side too. While she didn't mention Dylan by name, she did share Moses's piece.
"I never wanted to involve myself in the social media debates involving my father, but there comes a point when I realize that I can either continue pretending that none of this is going on, or stand up for him," Bechet wrote on Facebook. "He has been nothing but supportive and loving, and now it is my turn to support him."
She added, "I want to thank [Moses] for sharing his personal experiences so that people may begin to learn the truth about our family."
Allen and Mia Farrow dated for more than a decade before they split in 1992, when she discovered that he was having an affair with her adopted adult daughter Soon-Yi Previn. During their custody fight over minors Moses, Dylan, and Ronan (then known as Satchel), Mia accused Woody of molesting Dylan. While the state prosecutor said there was probable cause for a trial, he said he didn't want to put Dylan through the process. However, an investigation by Yale-New Haven Hospital found no evidence that sexual abuse had taken place. Woody has always maintained his innocence.
Other family members have taken sides too. Journalist Ronan Farrow, for instance, has long protected his sister. He did it again after Moses's latest words on the subject.
All I'm going to say about efforts to deflect from my sister's allegations: pic.twitter.com/IRrj5fzMqV
— Ronan Farrow (@RonanFarrow) May 24, 2018
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Everytime I order this dish, I will be addicted to the truffle aroma and taste. And I will also be shocked at how much this dish can be. To me, it is just fries and oil! But when I bought the truffle oil myself, I knew that it is not a cheap topping for the fries. But I simply cannot resist not having it. So I always have a bottle of truffle oil ready in my kitchen to put on fries, not forgetting the parmesan cheese.
Deep fry frozen fries for 10 mins over high heat.
You may also airfry for 10 mins at 180 deg C.
Strain the fries and pour truffle oil over. Mix well.
Add salt or truffle salt and mix.


text:
Retirement age shifts have been attributed to the global pandemic. Covid-19 has dramatically altered Americans' retirement plans.
A new study from Northwestern Mutual, found that 35% of American workers have decided to revise their target retirement age. This includes a change in plans to either delay or postpone their retirement age. Almost a quarter (24%) expect to retire later than planned, while 11% plan to retire earlier. The Northwestern Mutual study indicates Gen Zs and Millennials plan to retire prior to age 60 – the former at 59.4 and the latter at 59.5. The average age people expect to retire is 62.6, down from 63.4 in 2020. The pandemic has caused Americans to adjust their retirement age timelines. Interestingly, some are feeling confident enough to retire sooner. At the same time others have decided to delay their exiting the workforce.
Among those planning to delay retirement due to the pandemic there are many reasons. Around 39% said they would push back their retirement date three to five years. More than a third (35%), however, said their anticipated retirement date has shifted back more than 10 years! This decision could have serious ramifications by stifling upward mobility in the graying-of the American workforce.
Here are the top reasons survey respondents gave for delaying retirement:
Wanting to work and save money given additional flexibility with their workplace – 55%
Concerns about rising costs like healthcare and/or unexpected medical costs – 50%
Having to dip into retirement savings – 24%
Taking care of a relative/friend; responsible for additional dependents – 14%
Among those planning to retire sooner than anticipated, nearly half (18%) said they would move their targeted retirement age up by three to five years. Here are the reasons they gave for doing so:
Wanting to spend more time with loved ones – 42%
Focusing on hobbies/priorities outside of work – 33%
Realizing their personal mission is more important than saving more – 29%
Work situation has changed (laid off, etc.) – 28%
Although people are saving more, they recognize that they will likely need more money in retirement. On average, respondents to the Northwestern Mutual survey had $98,800 saved for retirement – up from $87,500 last year. However, they also said they expected to need more than $1 million to retire comfortably, compared to $950,800 in 2020. And although overall retirement savings are up, 43% believe they may outlive their savings, up from 41% last year. Respondents are taking proactive steps to address this concern, including:
Increasing savings – 29%
Putting together a financial plan – 22%
Discussing options with their family – 18%
Purchasing investments – 18%
Seeking advice from a financial advisor – 18%
When it comes to retirement income, more than a quarter of people (26.5%) expect their 401(k) to be their primary source, tied with Social Security (26.5%). Personal investments or savings were a close second (23.8%). Nonetheless, 19% of those surveyed said it's not likely that Social Security will be available to them, and 43% said they could imagine a time when Social Security no longer exists.
Plan sponsors should continue to encourage workers to start saving for retirement as early as possible. Plan sponsors should be active in educating participants on the actions they can take to improve their savings and chances of retirement success. In addition, plan sponsors should remind employees to consider their priorities when thinking about a targeted retirement age. This should include when to retire, how to retire, and where to retire. The overall goal is to encourage eligible employees to take action now. That is the best way to make sure they have enough money set aside to achieve their goals.
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Welcome to Chalk & Cheese Comics!
Praise for Chalk and Cheese!
The characters and events depicted in these comics are mostly fictitious, and any similarity to actual persons, living or dead, or to any actual events, firms and institutions or other entities is coincidental and unintentional except where it's not, in which case it is done in the spirit of satire and parody with jocular intent and just a smidgin of irony. In addition, the views and opinions expressed by said characters are their own and do not necessarily represent those of their creator, Tim Warnes, who really likes ducks and thinks it's both unsavoury and unsanitary to eat anything off a pavement (or sidewalk as the Americans say). Chalk & Cheese is under copyright © to Tim Warnes. Sharing of the comics is permitted only through social media platforms. The reproduction, adaptation or exploitation of the comics in any form for personal or commercial gain without the prior permission of Tim Warnes is illegal and strictly prohibited. Any trademarks mentioned are the property of their respective owners. Okay, you can stop reading now. Go on, shoo.
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text:
Home Around the state Mana Group breaks ground on massive Mana Common project in downtown Miami
Mana Group breaks ground on massive Mana Common project in downtown Miami
Moishe Mana's Mana Group has broken ground on its Mana Common project in downtown Miami.
"This is a crucial first step as we work to reinvigorate the historic downtown and transform it into an economically vibrant commercial neighborhood, blending the best in art, entertainment, fashion, technology and more," Mana said in a news release.
Over the years, Mana has spent in excess of $350 million to buy up more 50 properties, making him the single largest landholder in the downtown core, the Miami Herald has reported.
The first stage of the project will be at the Flagler Station building at 44 E. Flagler St. the interior will be torn out to create about 20,000 sq. ft. of retail and office space. There will be an incubator for high tech companies in the building.
The Miami International University of Art and Design and Studio Enterprise will relocate to a 13-story office building at 155 South Miami Ave. This structure will also house a five-floor startup hub.
As well, Mana plans to build five commercial galleries, two restaurants and provide a space for talks and screenings on Southeast First Street.
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