→HTC PM4000 Review – Worth your hard earned money?
HTC PM4000 Review – Worth your hard earned money?
A good miter saw stand can make cross-cutting large pieces of stock down to the sizes you need an easy job. Having a bad miter stand, or worse, no stand can make the job very difficult. A miter saw stand should offer support for the piece you are cutting as well as a solid base to hold to saw so your only concern is making accurate cuts.
The Folding HTC PM4000 Portamate stand has some very good features for the beginning owner as well as the long time handy- man. This review aims to help you decide if it is the right stand for your specific needs.
Is the HTC PM4000 Portamate Miter Saw Stand the Right Stand for You?
The Portamate stand comes with two support "T's" to hold both sides of your stock. The outrigger supports can be extended to hold just over 9 feet of stock and are rated to hold just over 500 pounds.
Setup of the Portamate proved to be straight forward and simple. In the box you find the supports, legs and hardware to assemble your miter saw table. From unboxing to making my first cut I'd say maybe 45 minutes passed.
The pieces for the HTC PM4000 are hollow steel that feels very sturdy, with good welds and very well down powder coating.
The phrase, "You Get What You Pay For" comes to mind with this stand. While it is on the cheaper side of most stands you'll see, it is fairly sturdy and seems to be built very well. It folds up quickly to allow you to move it around your worksite or to store it away. Other stands have more features but this one is a good basic miter saw stand that gets the job done.
One of the main functions of a table is to hold your miter saw securely while making cuts. The HTC PM4000 was able to do this for two different saw I own, a 10 inch and a 12 inch. The HTC PM4000 was able to accommodate both with only small adjustments.
Probably my favorite feature of the HTC PM4000 is the price. I could buy a more expensive stand but I honestly don't think it's worth it for what I need. While I use my miter saw on a lot of projects, I'm not a professional carpenter. I was able to get the PM4000 for just under $80, which is right about where I'd like to be.
From the start, I noticed that when extended the T supports weren't quite square with the cutting surface on my saw. While readjusting the T supports I noticed that clamping them in place led to them going off square. Not a big deal if you are okay with sanding or using putty to fill in any off-center cuts, but, for fine furniture making where precise cuts are needed this will cause a problem.
I also noticed when extended all the way out to their 9-foot extension the supports would shake quite a bit during my cut. I was still able to keep the piece I was cutting relatively straight but I can see this causing issues with lighter pieces.
The HTC PM4000 Portamate can be found from many online sellers. Below are sellers I think have the product for the best price and offer the fastest shipping.
Walmart.com offers free 3-day shipping on the HTC PM4000 and provides in-store pickup. You can also pay around $25 for one-day shipping if you need it quickly.
Amazon.com has the Portamate for a very good price and offers free 3-day shipping for Amazon Prime members. If you aren't a Prime member Amazon will still ship the item free but it will take 5-8 business days, which is still a good deal.
I also liked the deal that Shop.com offered on the PM4000. If you aren't familiar with the site you get money back on purchases that you can then use for other things sold on the site. Shop.com ships anything over $50 for free but could take anywhere between 7-14 days to arrive.
While I must say the stand exceeded my expectations at the price point it was at ($65-$80), I felt there were some things it fell short on. Getting and keeping the supports straight and level with my miter saw proved to be a chore. But, the stand is very sturdy and was able to accommodate both of my miter saws without issue.
I would call this miter saw stand an entry level or "hobby" stand for either the professional that doesn't use his miter saw all the time or for the home handyman who needs a stand to help with weekend projects. It's not a bad stand by any means, it's just not the best you can buy. It is much cheaper than other stands, but other stands seem to offer a bit more stability and less re-configuring.


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Health and Safety incidents become biggest loss driver for organizations
Organizations focused on risks including cyber-attack and IT outages underrate impact of more frequent events
Health and safety incidents have become the leading financial loss drivers for businesses around the globe, with cumulative losses now outstripping the costs of more high-profile disruptions such as cyber-attacks or IT outages.
Meanwhile, political change has entered the top ten list of future threats for the first time since 2015, while Blockchain and Artificial Intelligence are new risks which rank amongst top sources of potential disruption in the year ahead.
These figures stem from the annual BCI 2019 Horizon Scan, published today in association with BSI (British Standards Institution). The report analyses the risks and threats recognized by 569 organizations worldwide, comparing these against the impact of actual disruptions over the past year. Now in its eighth edition, the 2019 Horizon Scan reveals a significant gap between perceived risks and actual issues from the past 12 months.
For the year ahead, organizations are most concerned about high-impact events, including cyber-attacks, IT outages and extreme weather events, despite the fact that other incidents recurred more often and have a cumulatively higher impact. Some of the threats perceived to be low risk are being underrated when looking towards future resilience.
The clearest example of this is health and safety risks. The 2019 Horizon Scan totalled up the costs for surveyed organizations which suffered losses of more than 7 percent of annual turnover, and found that health and safety incidents cost $1.186 billion in 2018. Despite the frequency and cumulative cost of these incidents, organizations continue to perceive their impact as relatively low, ranking them twelfth on the list of top risks for 2019.
Howard Kerr, Chief Executive at BSI, commented: "It is easy for leaders to be kept awake at night by high-profile risks such as cyber-attacks, technology disruptions and IT outages. But they must not ignore the smaller, more frequent risks that steadily erode the bottom line. Organizations that do not take all threats they face seriously, or develop plans to manage them, are exposing themselves to not only reputational loss but what can become quite severe financial costs. Achieving true Organizational Resilience means identifying not only the big risks but also the under-rated issues that may just seem 'business as usual' and can easily be missed."
Other key findings of the 2019 Horizon Scan report include:
Political change is predicted to be one of the top ten disruptions in the next 12 months but the financial aspect of political change seems to be neglected, as threats related to exchange rate volatility and higher cost of borrowing do not appear in the top ten.
Organizations with business continuity plans in place for more than a year suffer fewer disruptions than their peers; they report lower losses (6%) than the average (7%) from disruptions in the last twelve months.
Organizations direct a lot of time and attention towards risks that were previously considered 'black swans' – events that struck as a surprise, with a high impact on those affected. These events then become a key focus of attention. Risks such as critical infrastructure failure and natural disasters are among the most anticipated disruptions with high risk scores (5.47 and 5.43 respectively).
Tim Janes, Chair of the BCI, commented: "For continuity and resilience practitioners the 2019 BCI Horizon Scan report provides an invaluable information resource. The findings and analysis provide insights that can inform and confirm planning assumptions and bring fresh ideas to benefit your exercise scenarios and continuity programme."
- ENDS -
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Students contributed their own painted panels to this cross.
One young artist included a self-portrait and examples of some cartoon drawings.
Students used collage and drawing to express their thoughts and dreams.
There's a spotlight on the works of young artist Maliya Gandy in the show.
The important work being done by the Lighthouse Youth Center is recognized at the current exhibition at the Oxford Arts Alliance.
Students at the youth center were asked to create art to complete the phrase, "I will become...," and the show presents their answers in drawings, collage and paintings. Their works, some left unsigned, have universal dreams both big and small, and speak of finding happiness and focusing on goals.
There's one paper filled with whimsical drawings of animals and a central self-portrait of their creator. "Cartoonist," which is one of the life goals posted on the gallery walls, clearly applies to this young artist.
Elsewhere, you can see the students' love of animals, sunshine, sports and – since this is a faith-based center – religion and God. There's a cross made of individual popsicle-stick panels that shows a bright mix of themes – the Mexican flag, a woodland road, and more. There's also a spotlight on the works of Maliya Gandy, who uses a variety of media to express herself.
In terms of the future lives of these young people – whether they go on to be artists or not – this exhibition will make an impact. Being in an art show with their peers, and getting their moment of acclaim, will pay untold dividends in the years to come, no matter where their paths take them.
This show is precisely what makes the Arts Alliance such a vital part of the community.
"I Will Become" continues through Aug. 9 at the Oxford Arts Alliance (38 S. Third St., Oxford). Gallery hours are Tuesday through Saturday from 10 a.m. to 4 p.m. Visit www.oxfordart.org.


It's pretty bad when even the judge that heard your case can't believe that you're free to roam the streets. Of course I'm talking about Casey Anthony and her infamous acquittal nearly 2 years ago. Just when you thought that anyone who was any body had already weighed in on what seems to be a massive mishandling of justice, the judge finally is speaking. Belvin Perry sat on the bench for 41 days listening to 300 pieces of evidence being introduced and over 90 witnesses took the stand to testify. According to the May 27th print edition of GLOBE, Perry was sure that Casey was heading for a needle in her arm.
Instead Perry had to reread the verdict several times to himself before announcing it because he couldn't believe his eyes. Perry believes that the jury was handed more than enough evidence to warrant a first degree murder conviction and he was as disgusted as the rest of the country when Casey walked away free. He believes that she absolutely got away with murdering her two-year old daughter Caylee in cold blood.
Perry believes that the jury didn't consider the evidence while deliberating because it took only 11 hours to reach a verdict. A thorough look back at everything should have taken longer. They were just anxious to get out of their and on with their lives.
Perry also believes that Casey will get what she deserves eventually. He thinks she'll be a victim of a street crime and that some random person will realize who she is and be unstable enough themselves to take justice into their own hands. Do you think Perry is right? Will the notorious party chick end up dead on a sidewalk somewhere? Tell us your thoughts in the comments below!


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UofL-led campaign for LGBTQ adolescents emphasizes parental support
and Shelbi Glover
Embrace the Journey campaign
In the United States, high school students who identify as lesbian, gay, bisexual, transgender and questioning (LGBTQ) are almost five times more likely to attempt suicide than their cisgender, heterosexual peers, according to the National Alliance on Mental Illness.
A new campaign is attempting to change that statistic in the Louisville area.
"Embrace the Journey," led by Ryan Combs, PhD, assistant professor, University of Louisville School of Public Health and Information Sciences, and Maurice Gattis, PhD, associate professor, UofL Kent School of Social Work, began with one question: "How can we make a difference in LGBTQ mental health?"
"We wanted to understand the health needs of LGBTQ adolescents in Louisville. We learned that the largest concern locally is mental health, especially depression, anxiety and suicidality," Combs said. "We designed a campaign to target parents because they play such a key role in the mental health of LGBTQ youth."
In 2017, UofL's LGBTQ+ Adolescent Health Study was launched – the first of its kind in Louisville. The study found 100 percent of participants had heard homophobic or transphobic language, 61 percent felt unsafe and 27 percent had experienced physical violence at school. To combat these findings, "Embrace the Journey" was developed through the guidance of local health providers, public health professionals, LGBTQ+ youth and community members.
The campaign launched recently, as organizers spoke to participants and handed out posters at Louisville Pride. The posters read: "LGBTQ+ youth are more likely to experience depression, anxiety, and suicide – supportive parents greatly reduce this risk."
Through the campaign's website, embracethejourneylou.org, parents can find hundreds of resources, including advice from other parents, personal narratives from youth and a glossary of LGBTQ vocabulary.
The campaign was developed with grant funding from both the Cooperative Consortium Transdisciplinary Social Justice Research and JustFundKY, and operates closely with Louisville Youth Group.
"Though educating their parents can't solve everything LGBTQ+ youth face, it's a great place to start especially when the statistics speak so loudly for themselves," Combs said. "When parents support their kids, youth have better mental health outcomes."
Cooperative Consortium Transdisciplinary Social Justice Research
JustFundKY
Louisville Youth Group
Shelbi Glover


S.E.R.R., a 501(c)3 nonprofit, works to build a culture of peace, promote education and action for reconciliation among peoples and for reconstruction of the social and material resources of society.
Board President: Cheryl T. Desmond, Ph.D.
Please make a donation via check to SERR and send to 1518 Marietta Avenue, Lancaster, PA 17603.
SERR Delegation at the U. N.'s Commission on the Status of Women 60th Summit-March 2016Type Reverend Marta Benavides, Mrs. Elsy Comerota, Ms. Marilyn Weaver, Ms. Emily Stengel, Ms. Martha Harris, Dr. Tracey Weis, and Dr. Cheryl Desmondyour paragraph here.
S.E.R.R. is based in the United States and collaborates with other groups & organizations worldwide, working together for the common good, with a focus on El Salvador.
January 1997 - First of several intercultural & educational exchanges between U.S. & El Salvador.
August 2004 – SERR recognized as a 501(c)3 organization.
January 2005 - 2015 Museo Aja established in Santa Ana, El Salvador. Ongoing support of initiatives in El Salvador: The Ecological House, The Permaculture Farm, Youth programs and mentorships, The XXIII Century Free University & programs, The Wisdom Institute on Indigenous Practices, Culture, & Art.
March 2005 - 2016 - Participation in United Nations processes, e.g. Financing for Development, Rio+20; Lima Climate Change Summit, Commission on the Status of Women, Forum on Indigenous Peoples, International Program on Aging, and the new Sustainable Development Goals. Local observation of U.N. International Days. Programs, free and open to the public, in U.S. and El Salvador.
October 2016-2017- Millersville University/(MU)SERR program on Women Running for Political Office; MU/SERR program on the Doctrine of Discovery; MU/Ebenezer Baptist Church/SERR Middle School Girls Empowerment Summit.
November - December 2016: Responses to post Presidential Election student actions on MU campus. Rally - Standing with Standing Rock Rally, Penn Square, Lancaster, PA.
11/1/2017 - Jewish Family Services Program- Creating a Safe Environment for Diverse Populations - C. Desmond, moderator.


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Conveys People Stock Photos and Images
senior Manager conveys to the employee the financial document
Beautiful brunette sitting in taxi conveys driver money for travel
Manager conveys to the employee the documents in the office
Mass Rapid Transit, MRT Metro system, Singapore
Yongxiu. 21st July, 2017. A boat conveys people at the submerged Dahuchi section of Yongxiu-Wucheng Road in east China's Jiangxi Province, July 21, 2017. Water level of Wucheng hydrological station of the Poyang Lake reached 18.96 meters at 6:00 p.m. Friday. The flood inundated the 5.05-kilometer-long Yongxiu-Wucheng road. Credit: Song Zhenping/Xinhua/Alamy Live News
Paintography. Unique artistic effect conveys a story
Crumpled ballot paper, symbolic image for non-voters or election frustration
Crumpled letter of termination to an employee, Mit sofortiger Wirkung gefeuert, German for fired with immediate effect
Crumpled letter of termination to an employee, Mit sofortiger Wirkung arbeitslos, German for unemployed with immediate effect
Crumpled letter, Mit sofortiger Wirkung Hartz 4, German for with immediate effect, Hartz 4, German welfare benefits
view from the top. senior Manager conveys to the employee the financial document.
Misty, view of Mont St. Michel conveys a sense of mystery.
(140912) -- HYDERABAD, Sept. 12 (Xinhua) -- Indian tennis player Sania Mirza poses for photos to promote a campaign of People for the Ethical Treatment (PETA) in Hyderabad, India, on Sept. 11, 2014. The campaign conveys a message asking people to become 'angels for animals' by adopting homeless dogs and cats. (Xinhua/Stringer)
Venice, California, USA. 9th Dec, 2013. A portion of the Venice sign conveys the cold weather gripping Southern California this past week. Additionally, a series of snowy and icy storms swept through the southern and northeastern United States over the weekend, leaving at least five people dead and causing the cancellation of thousands of flights Credit: Jonathan Alcorn/ZUMAPRESS.com/Alamy Live News
Quito, Ecuador. 18th Nov, 2016. Chinese President Xi Jinping makes a video call with staff members of the ECU-911 center in Portoviejo in the quake-hit coastal province of Manabi and conveys greetings to Ecuadorian people affected by the earthquake, in Quito, Ecuador, Nov. 18, 2016. Credit: Lan Hongguang/Xinhua/Alamy Live News
Dec. 9, 2013 - Venice, California, U.S - As a plane flies overhead, a portion of the Venice sign conveys the cold weather gripping Southern California this past week. Additionally, a series of snowy and icy storms swept through the southern and northeastern United States over the weekend, leaving at least five people dead and causing the cancellation of thousands of flights. (Credit Image: © Jonathan Alcorn/ZUMAPRESS.com)
Shanghai, China's Shanghai. 26th May, 2019. Liu Jianqiang (3rd L), a teacher from the College of Dance of Shanghai Theatre Academy, conveys information through one of team members at a dance class for hearing-impaired people in Minhang District, east China's Shanghai, May 26, 2019. Gumeicaiyun in Minhang District is a dance group composed of people with hearing impairment. The 20-member team, aged between 20 and 40, is trained weekly by teachers from the college of dance of Shanghai Theatre Academy. Credit: Fang Zhe/Xinhua/Alamy Live News
March 5, 2018 - A theatrical drama dealing with the harsh conditions faced by Gazans in their daily life is staged at the theatre in Gaza City. The play was watched live by the Dutch public via the Internet. The drama conveys to the world the dire reality experienced by the people of Gaza as a result of the Israeli siege on the Palestinian enclave. The play was written and directed by Rafat Al Aydi and is part of the Theatre Day Productions (Credit Image: © Ahmad Hasaballah/ImagesLive via ZUMA Wire)
(190504) -- ZUNYI, May 4, 2019 (Xinhua) -- Luo Minggang conveys packed tea leaves at Dalian Village of Tuxi Township in Fenggang County of Zunyi City, southwest China's Guizhou Province, May 3, 2019. Luo Minggang, a farmer in Dalian Village, established a tea cooperative with some villagers in 2007 as Fengyang ramped up efforts to develop tea industry as a pillar industry. After a few years of exploration and hard work, Luo became an expert in tea leaves caring, picking and processing and won many awards in national tea contests. Now the tea cooperative has attracted more than 200 people to jo
Singapore Mass Rapid Transit, (MRT) underground metro system
Man knocking on an abandoned house blocked off door at dusk. image conveys a sense of loneliness, despair and desolation.
Man knocking on an abandoned house blocked off door at dusk. image conveys a sense of loneliness, despair and desolation
Teenage boy (15-17) standing by bus, side view
Boy (11-13) standing with train in background
Boy (11-13) standing with bicycle, portrait
This portrait of a relaxed mature gentleman conveys a genuinely friendly nature and relaxed attitude
Elderly man alone Hand on a walking cane with rounded shoulders Standing at water edge gazing towards the horizon
1993 - A young Somali boy holding one of the PSYOPS leaflets up to the camera. The leaflet is a hand drawing a Somali man shaking the hand of a US Forces member. The drawing conveys to the Somali people that the US is trying to help end their suffering and is here as their friends.
Potato apple fruit or Bomurra cammerral. . Solanum sp?. . 'Having obtained from the friend to whom we are indebted for the original drawing of this plant, the name by which the aborigines of New South Wales distinguish it, we are induced to preserve the native appellation: though it certainly conveys no idea to the mind of any person unacquainted with the rude jargon of that people.'. . Handcoloured copperplate engraving from 'The Naturalist's Pocket Magazine; or, Complete Cabinet of the Curiosities and Beauties of Nature' (17981802) published by Harrison, London.
Teenage boy (15-17) standing at bus stop
Terracotta model of a boat. Culture: Cypriot. Dimensions: 1 1/16 x 2 5/16 in. (2.69 x 5.89 cm). Date: ca. 600-480 B.C.. In its simplicity, this piece conveys the fragility of ancient vessels in relation to the vastness and power of the sea, which was a source of food and livelihood for traders. It was a barrier and, simultaneously, a link for an island like Cyprus. Such boats were used by ordinary people. Museum: Metropolitan Museum of Art, New York, USA.
Teenage boy (15-17) standing by bus, waist-up, side view
Signs Word Cloud Concept
Tatwin conveys Guthlac by boat to Crowland. Guthlac Roll. East Anglia, circa 1210. Source: Harley Roll Y. 6, roundel 4. Language: Latin.
Search Results for Conveys People Stock Photos and Images


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You Ask, I Answer: Reducing Bias in Datasets
by Christopher S Penn | Jan 4, 2022 | AI, Artificial Intelligence, Marketing | 0 comments
In this episode, I answer this question: "Although AI can help solve various issues we face today, it can also create discriminatory algorithms. What solutions do you pose to solve the problems that AI causes?" Bias in datasets is an issue we all have to tackle.
Can't see anything? Watch it on YouTube here.
https://traffic.libsyn.com/secure/cspenn/yaia-reducing-bias.mp3
Download the MP3 audio here.
Got a question for You Ask, I'll Answer? Submit it here!
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Machine-Generated Transcript
What follows is an AI-generated transcript. The transcript may contain errors and is not a substitute for watching the video.
Alright, Lane asks, although AI can help solve various issues we face today can also create discriminatory algorithms.
What solutions do you post to solve the problems AI causes? Well, here's the thing.
Everything that happens with machines comes from human data, right? There's nothing that is outside of our existence.
And so the problems that we see with bias in AI and machine learning come from us, right? The humans, we are the problem.
And the problem occurs, the problem can occur in a variety of areas.
It can be the people we've hired, right, if people, the people we've hired have biases, it doesn't matter what else you do, you're going to have problems, right? So that's a huge part, it's an overlooked part of machine learning AI is what are the biases.
Remember, there's two kinds of bias, right, there is human bias, you know, maybe you don't like people with red hair.
Maybe you don't like people of a certain race, or religion or whatever.
Those are human biases.
And then there's statistical biases, which is just where a sample is not representative of the population, the sample is drawn from.
The people that you hire, have got to understand both of those, and know to look for both of those in the data that they're working with.
Right? So if you're looking at, say, some survey data that you've done before, in some market research, and you don't know how to check to see whether the sample is representative or not, you could have some really serious problems.
So people is first second overall strategy, is there a bias inherent in your strategy? I remember a number of years ago, my wife worked at a market research firm.
And the they were the epitome of what not to do in market research.
They were a conservative sort of Think Tank.
And people would come to them saying, I need research that backs up this point of view, by anybody who knows anything about market research and statistics knows that that's pretty much the worst way that you can do market research other than just making things up completely.
And so the strategy can have biases in it.
The data can have biases, and there are mitigation tools for that, for toolkits, for example, like IBM's AI fairness, 360 toolkit that can look at your data and say, Hey, these look like protected classes like gender, or religion, or ethnicity.
And it looks like these are non representative values in here like, hey, for some reason, this entire dataset, which has a gender field, is like 98% men and 2% women, you might have a problem in your data.
So what these tools can do to identify biases in the data set their biases that can creep in, in the choice of algorithms.
And again, more advanced tools like IBM Watson Studio have some some protections built in to avoid those problems, or mitigate them or at least identify that there's a problem.
And then you get bias in the model as it drifts, right.
So you publish a model, it's in production.
And then over time, as it gets new data and learns from new data, it becomes less and less accurate, it drifts.
It also may have biases in it that cause drift.
The most famous example, this was back in 2016, Microsoft Tei.
They focus on Microsoft created a twitter bot.
And it learned from the tweets people sent it and it became a racist porn bot in less than 24 hours.
There were no protections on model drift.
And so each of these areas where bias occurs or can occur has some level of protection you can build into it, but you have to know to think about it to look forward to ask questions about it.
You've got to have a way to identify it in the hiring process.
You've got to have a way to for a safe way for people to raise concerns in the workplace, right if they see a strategy that's clearly biased in some way that's That's incorrect.
There's got to be a safe way for people to elevate their concerns and and have those concerns answered.
Again, using tools like fairness 360 for the data, using tools like Watson Studio for the algorithms and the deployment.
And monitoring your models for drift will help you reduce the potential for or the impact of bias and the thing is we have to, we have to be on the lookout for it.
And we have to accept that it is going to occur and remediate it.
And one of the big challenges that companies will run into is they will fight, tooth and nail sometimes to say that they are not biased.
Like it's not possible.
Well, have you checked, right? Do you know? Have you proven that bias does or does not exist? In any of the systems and if you can't, you've got a problem.
Treat datasets, models, algorithms and, and production systems.
guilty until proven innocent.
When it comes to bias.
Assume that there's bias until you prove that there isn't.
If you want to have the best possible outcomes really good question.
What Content Marketing Analytics Really Measures
How To Start Your Public Speaking Career
The Biggest Mistake in Marketing Data
Understand the Meaning of Metrics


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#### According to
Index Fungorum

#### Published in
Mycologia 95(3): 493 (2003)

#### Original name
Leccinum monticola Halling & G.M. Muell.

### Remarks
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redpajama_set_name: RedPajamaGithub


Anthony is the Trading and Research Analyst for JK Investment Group. Working alongside the advisors, he oversees the firm's overall research strategy.
After six years working in retail banking and investments, he has experienced almost all facets of the investment advisory business: research, trading, account management, and customer service. Combined with JK Investment Group's unique approach to research as based on Behavior Evaluation, Anthony uses his strengths in quantitative analysis to translate information into insight.
A Cleveland State University alum, Anthony continued his education to receive a Master of Business Administration with a focus in finance.
Outside of work, Anthony is avid about all things outdoors: camping, hiking, tennis, golf, etc. His passion for food and his hometown makes him proud of the food scene that has come to develop in Cleveland.


Breast cancer is something that has probably affected at least someone you know or someone in your not so distant family tree. My great grandmother had it and to date, I've been lucky to not have anyone else in my immediate family with it. I also don't know of anyone personally who has fought the battle or lost it. Since I come from a family full of girls and have my own, breast cancer is a serious issue and health concern. It's Breast Cancer Awareness Month, I wanted to share some ways one of my favorite beauty company's is helping the cause: Avon Breast Cancer Crusade!
Avon is working to fight this horrible disease by not only raising awareness but also by funds. In 1992, Avon Breast Cancer Crusade raised and awarded more than $640 million worldwide to support the breast cancer cause thus allowing access to high-quality breast cancer screening and treatment to those women medically under-served.
Avon Breast Cancer Crusade products are very affordable with 100% of the net proceeds donated to the cause! What a great way for Avon to give back!
Know the facts about breast cancer and download this free Breast Health Resource Guide by clicking here.
Marimekko Tote ($10.00) - Designed by Marimekko exclusively for Avon Breast Cancer Crusade, this cotton canvas totes features a pink-ribbon motif.
Crusade Sock and Foot Works Overnight Treatment ($7.99) - Achieve 24-hour pedi hydration and then slip into super-plush comfort with these no-slip grip socks.
Breast Cancer Crusade "Lips for Life" Tote ($5.00) - Kiss goodbye to Breast Cancer! This reusable tote rolls up and tucks easily into any handbag, small enough to take eveywhere.
Avon Walk "Hope Laugh Walk" Tee ($15.00) - Say it loud and proud with this brand new bold pink shirt!
Avon Walk "Real Men Wear Pink" Men's Blue Tee ($15.00) - For the supportive man in your life who has unwaveringly supported the cause.
More than 240,000 women, and 1,000 men, will be diagnosed with breast cancer in the U.S. in 2010.
More than 40,000 women and 400 men die each year from the disease.
There are more than 2 million breast cancer survivors in the United States.
One person is diagnosed approximately every 3 minutes, and one person dies of breast cancer approximately every 14 minutes.
People over the age of 50 account for 76% of breast cancer cases; while only 5% of breast cancer diagnoses are in people under the age of 40 and 18% are in their 40s.
Full-Disclosure: Attention contacted me with this sponsored content opportunity, per FTC guidelines.


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Yi-Lai on the prowl for M&A
October 7, 2020 in Business
Au: Given the current [low] interest rate environment, we are looking for new investment opportunities, preferably in the IT-related industry, which will give us promising returns. (Photo by Kenny Yap/The Edge)
CERAMIC and tile manufacturer Yi-Lai Bhd, which saw businessman Au Yee Boon emerge as the largest shareholder in July, followed by his appointment as executive director a month later, is looking for possible acquisition targets in the information technology sector and hopes to seal "two or three" deals before year-end.
Yi-Lai has been posting yearly losses since the financial year ended Dec 31, 2017 (FY2017), due to the slowdown in the property market. This has been compounded by the economic fallout of the Covid-19 pandemic, which resulted in its net loss widening by 94% to RM9.75 million for the six months ended June 30, 2020 (1HFY2020), from RM5.01 million a year ago.
However, the 39-year-old Au is working hard to turn around the company. On Sept 8, Yi-Lai announced its diversification into the IT solutions business via a joint venture (JV) with TechBase Solution Sdn Bhd, an IT solutions company founded and controlled by Au. Under the JV, Yi-Lai and TechBase will hold 49% and 51% of the shares in the yet-to–be-incorporated JV company respectively. The JV firm will provide blockchain technology and system integration services.
Au says TechBase, which has been in the IT solutions business for 14 years, has a 10% to 20% share of the market, offering products ranging from enterprise resource planning and sales management systems to business productivity solutions and website design and development.
Thus, he expects the diversification strategy to help turn around Yi-Lai as early as FY2021, but he is not stopping there.
"We cannot rely solely on the tile manufacturing and IT businesses. Given the current [low] interest rate environment, we are looking for new investment opportunities, preferably in the IT-related industry, which will give us promising returns. We are in talks with several parties and may finalise two or three deals by year-end," Au tells The Edge in an interview.
The financially strong Yi-Lai will have no problem funding the potential acquisitions as it has a debt-free balance sheet, backed by cash holdings and unit trust investments of RM82.7 million as at end-June.
Au says despite its diversification into the IT solutions business, the group will maintain its focus on the core tile manufacturing business.
"The tile manufacturing business is highly dependent on the property market, which may be soft for now, but it will recover. Before FY2017, it was generating good profit contribution for the group," he points out.
In the immediate term, however, Au says the group's earnings will be driven by its venture into the IT solutions business. "Eventually, I see the two businesses contributing equally to the group."
Yi-Lai has also embarked on an extensive cost-saving exercise, including waiving directors' fee until February 2021. Apart from that, it has set aside RM10 million in capital expenditure for the installation of a solar system for its manufacturing facilities. This will enable it to save on electricity consumption — which averages RM1 million per month — in the long term.
"The capex on solar energy will take about six years to break even but it will be a long-term investment to lower our utilities bills by about 10%," Au says.
As part of its turnaround plan, Yi-Lai will also ramp up its manufacturing efficiency. Its production facilities in Kulai, Johor, comprise a total of seven production lines with an annual capacity of 11 million sq m.
The synergies with TechBase will be gained from the implementation of IT capabilities, such as Industry 4.0 automation, in Yi-Lai's operations, says Au.
"Many processes in the factories are outdated by over a decade. With improved efficiencies, the facilities, which are currently running at full capacity, will be able to generate higher production output. We intend to enhance the efficiency levels across the business before making any further expansion plans. We do not foresee any more than RM5 million in capex for this," he says.
Yi-Lai — an original equipment manufacturer for well-known ceramic tile distributors such as Feruni and Niro Ceramic Group — is also planning a rebranding exercise for its Alpha Tiles, its flagship ceramic tile brand, with the aim of raising its marketing profile.
Last Tuesday, the group launched Talos Living Tiles, a new range of negative ion tiles, with an aggressive sales target of 30 million units in three years. To achieve this target, Yi-Lai has partnered seven retail dealers throughout the country to expand its market reach.
"Alpha Tiles is still thought of as a middle-range brand, but with the rebranding exercise, we will ride on Talos' upper market status to raise Alpha Tiles' branding profile," says Au.
The tile maker also plans to increase its exports of tile products to Singapore and Japan, where it has an existing customer base.
'No plans for backdoor listing via Yi-Lai'
According to Au, he has no plans for TechBase to go public in a backdoor listing via Yi-Lai.
However, he does not rule out the possibility of launching an initial public offering or going for a backdoor listing via other listed companies. Companies Commission of Malaysia data shows that TechBase's net profit grew 41% year on year to RM5.1 million in the financial year ended March 31, 2019, while revenue rose 76% y-o-y to RM10.2 million.
Apart from Au, whose shareholding in Yi-Lai stood at 14.04% as at Sept 10, other substantial shareholders include Gunung Capital Bhd with 13.75% equity interest, and Yi-Lai executive director Aaron Tan Jian Hong, who has a 10.13% stake.
Au says Gunung Capital serves as a strategic investor for Yi-Lai.
Year to date, shares of Yi-Lai have risen 66% to close at 88 sen last Wednesday, giving it a market capitalisation of RM128.1 million.
Source: https://www.theedgemarkets.com/article/yilai-prowl-ma
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Hotel Spotlight
Surf's Up and Spirits Are High at Block Island Beach House
by California Chaney
The Beach Bar. All photos by Read McKendree, courtesy of Block Island Beach House.
Block Island Beach House
Block Island, Rhode Island
Coastal chic, $$ (From $239)
Just twelve miles off the coast of Rhode Island, Block Island has long been a haven for New Englanders, who come for its long stretches of sandy beaches and striking bluffs, especially in the laid-back, dog days of summer. The quaint town packs a punch of classic Americana charm, with weathered, shingle-style Victorian buildings and lighthouses that have withstood the test of time and anchored sailors home after long Atlantic voyages. For more than a century, The Surf Hotel was the cornerstone of the small town, located on Crescent Beach with a wraparound porch that welcomed visitors and locals alike for sundowners and a place to lay their head after a long day at the beach. While the island gained popularity once high-speed ferries began commuting day-trippers, the property remained a mainstay, where the sandy beach meets the walkable, coastal town and the vibe is a surfer's delight.
In 2019, Lark Hotels, a New-England based hospitality company with a serious eye for jackpot fixer-uppers, purchased the property and lovingly transformed it to a coastal-chic haven, complete with a beachfront restaurant, coffee bar, and outdoor pool. The 46 guest rooms got a fresh coat of paint and a new contemporary style, with sun-kissed retro furnishings and restored balconies to spot the morning surf break. While the original Surf Hotel sign remains on the exterior wood cladding, the renamed Block Island Beach House infused its authentic oceanside character with shiplap walls, vintage surfboards strewn about, and well-lived-in soft linen and leather pieces to complete the airy common spaces. The outdoor beach bar offers barefoot seashell dining and refreshing cocktails with sweeping views of the ocean and a place to linger long after the sun sets. And because summers quickly floats away, guests are given a vintage Polaroid camera to use during their stay to preserve the happy, salty days until their return to the shores of sunny bliss.
Rates start at $239. Click here for reservations. Or contact the Fathom Concierge and we can book your trip for you.
The Vibe: A charming seaside surf shack.
Standout Detail: As the only oceanfront hotel on the island, the direct access to the best surf and sand is hard to beat.
This Place Is Perfect For: First timers to Block Island who want to hop off the ferry and head straight to the beach or easily walk and bike to explore the island without an agenda.
Rooms: Vintage surfboards line the hallways leading to the building's original 31 guest rooms, several of which have beachfront or village-facing balconies. While Lark preserved many elements of the former Surf Hotel's charm, the rooms received a welcome sprucing that balances the antique and contemporary vibes of the hotel. New this summer, the hotel expanded to a second building (formerly The Gables) to add an additional 16 rooms and suites with an outdoor pool. Bold wallpaper and white shiplap walls are adorned with vintage surfing photos and additional waxy boards, while four-poster beds, rattan chandeliers, and Moroccan area rugs create a haven to drift off after a day in the sun, along with the blackout shades and waffle kimono robes. Vintage Polaroid cameras are found in each room to take along to the beach or snap portraits of your crew or your pup (the hotel welcomes all pets).
On Site: To sink into the relaxing vibes here, take a dip in the guests-only outdoor pool tucked behind the shore with lounge chairs and umbrellas. But if the gentle lapping waves of Crescent Beach are calling your name, several surf and paddleboard rentals are within walking distance.
Food + Drink: On the standout Victorian wraparound porch is the hotel's anchor restaurant, The Surf Shack, serving BBQ, fresh fish, sandwiches, and salads with views of Crescent Beach. They also host weekly clambakes with live music. Before dinner, all good beach days end at the Beach Bar, where frosé and margaritas are served until sundown and the crunch of white seashells at your feet is the chef's kiss to a perfect summer day. Inside, the lobby coffee bar serves grab-and-go breakfast and lunch for afternoon adventures.
What to Do Nearby
Block Island's 17 miles of coastline will keep you happily occupied on the oceanfront: The hotel's backyard beach is the most popular in town for its soft sand and calm water. Nearby Baby Beach or Andy's Way are quiet, especially in the early mornings, when you can spot dolphins. And if you're looking to try your hand at surfing, Black Rock has the best surf and is gentle on beginners. If you want to explore the dry offerings of the island, rent a bike or scooter from Island Moped and head to Mohegan Bluffs on the southern shore of the island, where a 200-foot staircase leads you down to Corn Cover with sweeping views of the island and its sandy bluffs. Since most of the island is protected by the Nature Conservancy, there are over 25 miles of nature trails to explore with unique rolling hills and grassy meadows.
Filed under: Hotel Spotlight, Rhode Island
California Chaney
California is an editor at Fathom and DJ in New York City. You can follow her on Instagram @californiastarchaney. She travels for the music, views, and spontaneity. Read more: Articles on Fathom.


The 1940s Aunt Peg Apron features gathering at the waist band for fullness with ruffled trim at skirt bottom. A single pocket with extra long ties for snappy bow tying at the waist. A longer length provides a fuller skirt for voluptuous coverage in a half apron. Each is one of a kind. Order promptly as no two pattern combinations are duplicated..
The Aunt Peg 1940s ruffled half apron is a busy mix of fabric patterns.


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Burke & Hamilton Funerals
45 Gunnedah Road
Tamworth, New South Wales 2340
Alston Memorial Chapel, Lincoln Grove Memorial Gardens
1040 Gunnedah Road
More Obituaries for David KELLY
David John (Kelpie) KELLY
KELLY, David John (Kelpie) Passed away peacefully at Nioka, Tamworth Hospital on Saturday, 11th of January, 2020 Aged 58 years Much loved son, father, pop, brother, uncle and great mate to many. Relatives and friends of the late David Kelly are warmly invited to attend his Funeral Service, commencing at 10.00am, Wednesday, 15th, January, 2020, in the Alston Memorial Chapel, Lincoln Grove Memorial Gardens, 1040 Gunnedah Road, Tamworth. By request no flowers. Donations may be made in lieu of flowers to the Friends Of Nioka. A donation Box will be available at the chapel. Burke & Douglas Funerals Funeral Director's Association of NSW Accreditation No. 12012-03 [email protected] (02) 6765 3999
Published in The Northern Daily Leader on Jan. 14, 2020
What will you miss most about David John (Kelpie) KELLY?
Inform family & friends of David's passing.


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Discover client recommended agencies Skip to content
Microsoft's UK CMO: 'We're on the cusp of the fourth industrial revolution'
By Katie Deighton - April 22, 2016
Brands need to be "waking up" up to the potential of bots and be aware of sensors, the cloud and machine learning as we approach the "fourth industrial revolution", Microsoft's UK chief marketing officer told The Drum.
Paul Davies, who spoke on the Advertising Week Europe panel dubbed 'How smart cities will transform advertising', explained how Microsoft is already looking to an automated, connected future when designing and collaborating on innovations.
"We have an app experience for people who are visually impaired, which is powered through bluetooth sensors to help them walk around all the way, through an electric car sharing company called Autolib," he said. "Their mission is to reduce the number of cars in Paris by 25,000 in the next seven years...using data and the cloud to empower that."
Davies believes the world is "on the cusp of the fourth industrial revolution, the digital revolution". This, he said, will be driven by omnipresence of sensors and devices, the cloud's ability to link said devices and intelligent machine learning, as well as the increased capabilities of big data analysis.
"When you pull all that together you can create some really exciting and transformational experiences for businesses and consumers," Davies said.
Finally, the marketer said artificial intelligence will probably make the most noise in the retail sector. He added that the concept of bots in particular is "very exiciting", however failed to bring up his company's haywire 'Taybot' Twitter experiment, which went into meltdown in March.
This article is about: World, Microsoft, TayBot, Artificial Intelligence, The Cloud, Fourth Industrial Revolution, Modern Marketing, Technology, Brand


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BioMed Research International
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Complete Special Issue
Volume 2016, Article ID 5986519, 7 pages
Molecular Cloning and Characterization of Full-Length cDNA of Calmodulin Gene from Pacific Oyster Crassostrea gigas
Xing-Xia Li,1 Wen-Chao Yu,2 Zhong-Qiang Cai,3 Cheng He,2 Na Wei,2 Xiao-Tong Wang,2 and Xi-Qing Yue1
1College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
2School of Agriculture, Ludong University, Yantai 264025, China
3Changdao Enhancement and Experiment Station, Chinese Academy of Fishery Sciences, Changdao 265800, China
Received 6 January 2016; Revised 16 June 2016; Accepted 28 June 2016
Academic Editor: William H. Piel
Copyright © 2016 Xing-Xia Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The shell of the pearl oyster (Pinctada fucata) mainly comprises aragonite whereas that of the Pacific oyster (Crassostrea gigas) is mainly calcite, thereby suggesting the different mechanisms of shell formation between above two mollusks. Calmodulin (CaM) is an important gene for regulating the uptake, transport, and secretion of calcium during the process of shell formation in pearl oyster. It is interesting to characterize the CaM in oysters, which could facilitate the understanding of the different shell formation mechanisms among mollusks. We cloned the full-length cDNA of Pacific oyster CaM (cgCaM) and found that the cgCaM ORF encoded a peptide of 113 amino acids containing three EF-hand calcium-binding domains, its expression level was highest in the mantle, hinting that the cgCaM gene is probably involved in shell formation of Pacific oyster, and the common ancestor of Gastropoda and Bivalvia may possess at least three CaM genes. We also found that the numbers of some EF hand family members in highly calcified species were higher than those in lowly calcified species and the numbers of these motifs in oyster genome were the highest among the mollusk species with whole genome sequence, further hinting the correlation between CaM and biomineralization.
Calmodulin (CaM) seems to play important roles in regulating the uptake, transport, and secretion of calcium in molluscan shell formation, such as yesso scallop (Patinopecten yessoensis) [1], freshwater pearl mussel (Hyriopsis schlegelii) [2], and pearl oyster (Pinctada fucata) [3]. The pearl oyster CaM protein or calmodulin-like protein (CaLP) was found to interact with different target proteins in the mantle and the gill [4] and may regulate the calcite growth in the shell prismatic layer by inducing the aragonite nucleation and modifying the calcite morphology in vitro crystallization experiments [5]. The pearl oyster shell mainly comprises aragonite [6, 7], whereas the Pacific oyster shell is mainly calcite [8]. The higher level of calcite in the oyster shell may suggest that CaM has a different function in the Pacific oyster. To elucidate the role of CaM in shell formation in the Pacific oyster, we cloned the full-length cDNA of Pacific oyster CaM (cgCaM) and analyzed its characteristics.
2.1. Specimens, RNA Isolation, and Primers
Six organ types (hemolymph, mantle, digestive gland, gill, adductor muscle, and labial palps) were collected from slaughtered Pacific oysters, snap-frozen in liquid nitrogen, and stored in the Ultra-low Temperature Freezer (−80°C) until extracting RNA. The total RNA was extracted using Trizol reagent (Tiangen, China). All of the primers were designed referring to one of the predicted CaM sequences (CGI_10006482) deposited in OysterBase (http://www.oysterdb.com/), as described in Table 1.
Table 1: Primers used for CaM cloning and expression analysis.
2.2. Cloning the Full-Length cDNA
Full-length cgCaM mRNA sequences were got by 5′-RACE and 3′-RACE. For the 5′-RACE, the RACE-ready complementary DNA (cDNA) was got using SuperScript II (Invitrogen) and the primer GSP1; after synthesizing the cDNA, the deoxycytidine triphosphate and terminal deoxynucleotide transferase were used to add a poly-C tail to the 3′ end of the cDNA; the primer pair of GSP2 and AAP was used to carry out the first PCR, the product of which was reamplified by GSP3 and AUAP according to the same thermal profile, which includes 2 minutes of an initial denaturation at 94°C, then 35 cycles comprising 30 seconds of denaturation at 94°C, 30 seconds of annealing at 55°C, and 2 minutes of extension at 72°C, 7 min of final extension at 72°C, and holding at 4°C at last. For the 3′-RACE, Oligo dT-3 sites Adaptor Primer (Takara) and AMV Reverse Transcriptase XL (Takara) were used to get the RACE-ready cDNA. The temperature profile employed was as follows: 10 minutes of at 30°C, 30 minutes at 50°C, 5 minutes at 95°C, and 5 minutes at 5°C. All of the RACE-ready cDNA products were amplified using sense primers (GSP-3′ RACE) and antisense primers (3 sites Adaptor Primer, Takara), where the temperature profile was as follows: 5 minutes at 95°C; 30 cycles including 30 seconds at 94°C, 30 seconds at 55°C, and 5 minutes at 72°C; and then 7 minutes at 72°C. The PCR products of 5′-RACE and 3′-RACE were purified, ligated into the pMD18-T vector, and sequenced, respectively.
2.3. Expression Analysis of the cgCaM Gene in Different Organs
The mRNA levels of the cgCaM gene were measured using the method of Quantitative Real-time PCR. The quantities of cgCaM mRNA in different organs were standardized against that of elongation factor 1 (eLF1) mRNA to compensate for variations in volume of input mRNA. All of the reactions were carried out in a 20 μL volume, which contained 10 μL of SYBR Green Master Mix (Tiangen), 5 pmol of each primer, 7 μL of water, and 1 μL of cDNA obtained by reverse transcription from each tissue (hemolymph, mantle, digestive gland, gill, adductor muscle, and labial palps) RNA using Moloney murine leukemia virus reverse transcriptase (Tiangen, China). Each cDNA sample was amplified with the primers CaM-F and CaM-R in three duplicates, each cDNA sample with the primers eLF1-F and eLF1-R in three duplicates, and the negative control in three duplicates on the same 96-well microplates. The PCR program was used according to the recommendation in the manufacturer. The specificity of the PCR products was evaluated by melting-curve analysis. The data were analyzed using the method.
2.4. Sequence Character Analysis
The online tool, Compute pI/Mw, was used to predict the isoelectric point and molecular weight of cgCaM protein (http://ca.expasy.org/tools/pi_tool.html), and another online tool, the PSORT II program, was used to predict the N-terminal signal and cell location (http://psort.ims.u-tokyo.ac.jp/). Functional domain (IPR) prediction was performed at http://prosite.expasy.org/.
2.5. Phylogenetic Tree Construction
The CaM sequences of other mollusks were downloaded from NCBI and the CaM sequence from Hydroides elegans was used as an outgroup to root the tree. All the CaM sequences with complete CDS were got by the experimental methods in previous studies and downloaded from NCBI (http://www.ncbi.nlm.nih.gov/). A multiple sequence alignment was obtained using CLUSTALW. Phylogenetic tree was constructed using the neighbor-joining algorithm of MEGA 6 [9]. The robustness of the support for the tree was estimated based on 500 bootstrap replicates. In all of these analyses, the pairwise deletion option was used for handling alignment gaps as missing characters.
2.6. Calculation of the Numbers of EF Hand Clan Members in the Genomes of Multiple Species
We downloaded the Alignment file (Stockholm format) of the EF hand clan members from http://pfam.xfam.org/clan/CL0220, converted them into HMM file using hmmbuild tool in HMMER software and searched these motifs in the genomes of Caenorhabditis elegans, Schistosoma ansoni, Schistosoma haematobium, Capitella teleta, Helobdella robusta, Culex quinquefasciatus, Drosophila melanogaster, Octopus bimaculoides, Daphnia magna, Daphnia pulex, Ciona intestinalis, Branchiostoma floridae, Callorhinchus milii, Saccoglossus kowalevskii, Aplysia californica, Biomphalaria glabrata, Pinctada fucata, Lingula anatina, Acropora digitifera, Strongylocentrotus purpuratus, Lottia gigantea, Homo sapiens, Gallus gallus, Crassostrea gigas, Chrysemys picta, Pelodiscus sinensis, Lepisosteus oculatus, and Salmo salar using hmmsearch tool and calculated the motif numbers in these genomes. According to the degree of calcification, Caenorhabditis elegans, Schistosoma ansoni, Schistosoma haematobium, Capitella teleta, Helobdella robusta, Culex quinquefasciatus, Drosophila melanogaster, Octopus bimaculoides, Daphnia magna and Daphnia pulex were placed into the lowly calcified group; Ciona intestinalis, Branchiostoma floridae, Callorhinchus milii, Saccoglossus kowalevskii, Aplysia californica, Biomphalaria glabrata, Pinctada fucata, Lingula anatina, Acropora digitifera, Strongylocentrotus purpuratus, and Lottia gigantea were placed into moderately calcified group; Homo sapiens, Gallus gallus, Crassostrea gigas, Chrysemys picta, Pelodiscus sinensis, Lepisosteus oculatus, and Salmo salar were placed into highly calcified group.
3.1. Molecular Characteristics of cgCaM
The full-length cgCaM cDNA, which comprised 648 nucleotides, was obtained using the RACE technique. As shown in Figure 1, the ORF comprised 342 nucleotides and it encoded a peptide of 113 amino acids, the 5′ UTR 80, and the 3′ UTR 226 (GenBank accession number KM115543).
Figure 1: Sequence structure of cgCaM. The sequence highlighted in the upstream region indicates the 5′ UTR and that in the downstream region is the 3′ UTR. "ATG" in bold indicates the initiation codon and "TAG" in bold is the termination codon.
The cgCaM peptide was predicted to have an isoelectric point of 4.24 and a molecular weight of 12.86 kDa using the Compute pI/Mw tool. According to the PSORT II program, the cgCaM peptide was predicted to have no N-terminal signal peptide and it was expected to be located in the cytoplasm (probability = 60.9%), which is similar to the CaM and CaLP proteins in Pinctada fucata (pfCaM and pfCaLP).
After functional domain prediction, it was found that the cgCaM protein contained three EF-hand calcium-binding domain (CA_BIND) domains at amino acids 8–43, 45–80, and 81–113, and pfCaM also had three CA_BINDs (Figure 2). We did not identify an extra hydrophilic tail specifical for CaLP or any signal peptide in cgCaM [10, 11].
Figure 2: Functional domains of pfCaM, pfCaLP, and cgCaM. The InterProScan domain (IPR) was predicted at http://prosite.expasy.org/. The red block denotes the EF-hand calcium-binding domains (CA_BIND), which were located at amino acids 8–43, 45–80, and 81–113 in the Pacific oyster.
3.2. Expression Pattern of the cgCaM Gene in Different Organs
The mRNA expression levels of the cgCaM gene were examined by real-time PCR and compared indifferent organs (hemolymph, mantle, digestive gland, gill, adductor muscle, and labial palps). As shown in Figure 3, cgCaM was expressed in all six of the tissue types that we investigated, where the cgCaM mRNA expression level was highest in the mantle and lowest in the gill ().
Figure 3: Relative expression levels of the cgCaM gene in different organs of Pacific oyster, that is, hemolymph, mantle, digestive gland, gill, adductor muscle, and labial palps. Asterisk () denoted that the cgCaM gene was expressed significantly highly () in the mantle and significantly lowly in the gill ().
3.3. Phylogenetic Tree of Peptides Orthologous to CaM
As shown in Figure 4, group 3 appeared earlier than group 2, and group 2 appeared earlier than group 1. Based on the phylogenetic tree of CaM and CaLP, we found that several Gastropoda and Bivalvia CaMs (group 3) were more similar with the outgroup CaM, whereas other molluscan CaMs (groups 1 and 2) were obviously different from the outgroup, while cgCaM appeared in group 1.
Figure 4: Phylogenetic tree of peptides orthologous to mollusKan CaM. The peptides were divided into 3 groups including group 1, group 2, and group 3. CaM from Hydroides elegans was used as an outgroup.
3.4. The Numbers of EF Hand Clan Members in the Genomes of Multiple Species
It was found that the numbers of some EF hand family members, including EFhand_Ca_insen, EF-hand_1, EF-hand_2, EF-hand_3, EF-hand_4, EF-hand_5, EF-hand_6, EF-hand_7, EF-hand_8, EF-hand_9, EF-hand_10, EF-hand_11, EF-hand_like, and IQ, in highly calcified species were higher than those in lowly and moderately calcified species (Figure 5). Interestingly, the numbers of above motifs in oyster genome were the highest among the mollusk species with whole genome sequence (Figure 6).
Figure 5: The distribution of EF hand motifs in lowly calcified, moderately calcified, and highly calcified species. EFhand_Ca_insen, EF-hand_1, EF-hand_2, EF-hand_3, EF-hand_4, EF-hand_5, EF-hand_6, EF-hand_7, EF-hand_8, EF-hand_9, EF-hand_10, EF-hand_11, EF-hand_like, and IQ belong to EF hand clan.
Figure 6: The numbers of some EF hand motifs in whole genomes of some mollusk species. (a) The motif numbers without adjustment; (b) the motif numbers adjusted using genome size.
The shell is one of the most important features of mollusks because it is related to their health and growth. Thus, elucidating the mechanism of shell formation will be beneficial for mollusk culture. PfCaM and pfCaLP are believed to play important roles in shell formation of the pearl [10, 11] oyster and it was concluded that cgCaM may play a different role in shell formation by the Pacific oyster because the composition of the Pacific oyster shell is different from that of the pearl oyster. Determining the sequence characters, expression pattern, and phylogenetic location of cgCaM will facilitate further research into shell formation by the Pacific oyster.
The mantle is an important organ for shell formation [12, 13], although some other organs may also be involved in the process [14, 15]. We found that the cgCaM gene expression level was highest in the mantle, thereby suggesting that its function is probably related to shell formation. However, CaM is present not only in mollusks but also in other animals without shell, such as Hydroides elegans [16] (Figure 4), which indicates that CaM has fundamental roles in calcium metabolization but not limited to shell formation and it may be involved in various pathways. Interestingly, we found that Gastropoda and Bivalvia CaMs were present in each branch (group) of the molluskan CaM tree (Figure 4), which suggests that the common ancestor of Gastropoda and Bivalvia probably had at least three CaM genes. In addition, the CaLP genes were only present in group 1 and group 1 was far away from the outgroup, which indicates that the CaLP gene emerged later than the CaM genes.
It was found that highly calcified species had more EF hand clan members in their genomes (Figure 5), hinting the probable correlation between these motifs and biomineralization. As we all know, oyster had the large and thick calcified shells [14, 15]; we also found more EF hand clan members in its genome than in other mollusk genomes (Figure 6), so it could be deduced that more EF hand clan members may promote the formation of large and thick calcified shells. CaM mainly contained three motifs, EF-hand_1, EF-hand_2 and EF-hand_7, and may be involved in shell formation of other mollusks [1–3]; cgCaM also contained these three motifs and expressed highly in mantle (Figure 3), all of which hinted that cgCaM may be involved in oyster shell formation.
All authors have not declared conflict of interests.
Xing-Xia Li and Wen-Chao Yu contributed equally to this work.
This research was supported by National Natural Science Foundation of China (no. 31302181), Shandong Provincial Natural Science Foundation, China (no. ZR2013CM026), Key R & D program of Shandong Province (2015GSF115013), Modern Agricultural Industry Technology System of Shandong province, China (SDAIT-14-03), and Enterprise project (no. 2013HX007).
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The Service Technician reports to the Property Manager under the supervision of the Service Manager and performs general maintenance and repair to ensure apartment units and other property facilities are in good working order. Responsibilities include diagnosing, troubleshooting, and repairing heating, ventilation and air conditioning (HVAC) units; electrical appliances, outlets, and light fixtures; plumbing, carpentry, and locks. The Service Technician follows a planned preventative maintenance schedule and follows up with residents after repairs are complete. Additional responsibilities include, but are not limited to, assisting with preparing vacant apartment units for rental and also landscape and renovation projects.
ÂReceives requests for service maintenance, prioritizes work orders and handles each in the most efficient manner.
Examines and diagnoses problems with heating, ventilation and air conditioning units for property facilities. Determines the best method to repair or replace all or part of the unit. Makes repairs and/or replacements according to standard. Performs preventative maintenance on HVAC units by replacing filters, cleaning coils, etc.
Repairs and replaces furnished kitchen appliances such as refrigerators, stoves, washers and dryers. May contact an outside vendor to make more advanced or severe repairs or replacements.
Performs minor to moderate-level plumbing repairs, replacements, and/or installations including repairing leaks and removing clogs in sinks and toilets.
Performs minor electrical repairs and replacement of light fixtures and related items.
Repairs locks and other miscellaneous items.
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Malaysia expands investments in Indonesia with signing of MOUs, agreements worth US$3.1 bln
>Media & Events > News>Malaysia expands investments in Indonesia with signing of MOUs, agreements worth US$3.1 bln
Malaysia has continued to expand its investments in Indonesia via the signing of five memorandums of understanding (MoU) and agreements that will be sealed by the private sectors of both countries worth US$3.1 billion today, said Prime Minister Datuk Seri Ismail Sabri Yaakob.
The premier said Malaysia's total investments in Indonesia amounted to US$12.53 billion while Indonesian investments in Malaysia were worth US$1.16 billion in the second quarter of this year.
"I believe Malaysian investments in Indonesia are big," he told reporters in a media conference with Indonesia's President Joko Widodo at Istana Bogor in conjunction with his inaugural three-day official visit to the country which started on Tuesday.
Ismail Sabri also called for the involvement of Malaysian companies in the development of Kalimantan, which shares a border with Sabah and Sarawak.
Indonesia is building its new capital in eastern Kalimantan.
The country is an important trade and strategic partner for Malaysia, with the total trade between them worth US$15.67 billion in 2020, according to the prime minister.


Today is the third day of our Srimad-Bhagavatam classes. We are in the midst of relating the history of Ajamila and the glories of chanting the holy names of the Lord. We see here that the holy name is so powerful that one does not require diksa (brahminical initiation), or the five activities performed before taking diksa, to assure full success. Just by naming his son Narayana, which is the name of one of Lord Krsna's incarnations, Ajamila began chanting the Lord's Holy Name. He had he taken diksa when he first spoke the name of Narayana. Furthermore, he was so fallen that there was not a single sin he had not committed. He used to take intoxication and engage in other illicit activities. Such a person uttered the name of the Lord when he named his son Narayana, and received so much benefit.
Srila Visvanatha Cakravarti Thakura says that the very day Ajamila named his son Narayana, all his sins were finished – just by his first utterance of the holy name. After that, the rest of the holy names he called out constituted his sadhana. We see that all the while he was taking the name, he continued to act unlawfully – stealing, taking intoxication and so on. However, we should not consider his behavior at this point to be sinful. Yes, these activities were going on, but they had no power in them. You can understand it like this – if you put some peas in the ground, they will sprout and grow. Now roast some peas and try to grow them. Even if you fertilize the ground with many kilos of icow dung and give it plenty of water, they will not sprout. Similarly, all Ajamila's sins were burned, simply by his calling out the names of Narayana. Now his unlawful activities, which seemed like lowly fruitive activities in the eyes of ordinary persons, no longer constituted sin. His activities can be compared with a snake whose poisonous teeth have been pulled out. The snake still continues to bite because it is his habit, but there is no more poison. Similarly, now Ajamila's unlawful activities had no power to give any fruits to bind him. If a rope is burnt, its shape is still there in the ashes, but when one touches the ashes, the shape falls apart and cannot be used as a rope.
The result of Ajamila chanting the names of Lord Narayana was that he attained the association of the Visnudutas, who are associates of the Lord Himself, and inadvertently took diksa initiation from them. Up to that point his chanting was called nama-abhasa (the clearing stage of chanting), because whatever else he did, he had not committed any offences to a Vaisnava. He had not disrespected the Vaisnavas in this life or any previous life. By his nama-abhasa he received the association of the Visnudutas, who gave him diksa and explained to him the full glories of the holy names.
Srila Rupa Gosvami has promised: "One should stay in Vrndavana under the guidance of a sadhu, chant the holy names, hear Srimad Bhagavatam from the lotus mouth of a rasika Vaisnava and serve the Deity of the Lord. There is no doubt that by performing these five activities one will surely receive krsna-prema." However, there is one condition – there should be no disrespect or offence to the Vaisnava.
This is our dilemma. We are doing hari-nama, staying in the holy place and hearing Bhagavatam, but we are not really hearing. Sometimes, some of us only act as if we are following. We speak publicly on the Bhagavatam and give instructions to others, but we do not protect ourselves from offense to Vaisnavas. Joking and laughing, we somehow disrespect or criticize Vaisnavas. The holy name (who is God Himself) cannot tolerate this. Therefore, we deceive ourselves and we are deprived of the real fruit of chanting the holy name. In this way, many lifetimes are wasted.
Therefore, be very, very cautious to avoid committing, by any means, offence to the Vaisnavas; for offense to Vaisnavas is offence to the holy name. If you see another devotee doing something wrong, do not look. There are elevated Vaisnavas who will see their faults and rectify them. You cannot do so. Just tend to your bhajana. If someone else is not doing bhajana, why are you worrying about it? Just look at your own behavior. We do not see our own faults, but we want to see others' faults; and day and night we talk about this. Nowadays this is the fashion, and therefore we loose the chance to do bhajana.
Understand all this clearly. Wherever we see some kind of fall down, some disaster, some digression from bhajana or some material difficulties, the main cause for these is disrespect to the Guru and Vaisnavas. Ajamila was more fallen than fallen, but he did not disrespect anyone. He was sinful, but as soon as he had the association of Vaisnavas he stopped his sinful activities and was able to chant the pure holy name. Wherever there is a little bit of disrespect for the Vaisnavas, guru, saints, sadhus, the holy abodes of the Lord in this world, or the holy names, there is a decline in bhakti.
You must have heard the story of Prajapati Daksa. He cursed Sri Narada Muni, saying, "You gave my sons instructions on the performance of bhajana of the Supreme Lord, and now they have left home and family. You have ruined everything for me. For that I curse you that you will not be able to remain in one place longer than the time it takes to milk a cow." Sri Narada became very pleased, taking this as a benediction rather than a curse. But how do other persons react? There is a Hindi saying: if you place a thorn in someone's path, what will happen? That thorn will become three, like a trident, and will come back and pierce you. On the other hand, if you do good for others, you will be showered with flowers. We see what happened with Daksa Prajapati. He gave a curse, and by that he first disrespected the Vaisnava, then Guru and then God. Therefore, never keep bad thoughts in your mind to harm anyone. Even if someone is unjustly abusing you, just tolerate and not retaliate.
There is another very good example in the instance of Sati, also known by the names Uma and Parvati. She was wandering in the forest with her husband Lord Siva. Siva and Uma saw Lord Ramacandra crying for His wife. Because Ravana had kidnapped Sita-devi, Lord Rama was wandering here and there, calling out, "Oh, Sita! Oh, Sita!" Lord Siva saw Lord Ramacandra lamenting like this, and he paid his obeisances at the Lord's lotus feet from afar. Uma-devi asked, "My lord, to whom are you paying obeisances?" Siva answered, "Here is my Master. Here is my Lord Ramacandra. I am paying obeisances to Him." She questioned him, "How can He be God? He is running after His wife and lamenting. Siva answered, "That is His transcendental pastime. You can test Him, if you don't believe me." Then Siva left.
This pastime took place to show that Rama is never separated from Sita. His pastime is under the jurisdiction of the Lord's yogamaya (spiritual desire) potency. This is His human-like pastime (naravat-lila). He was actually crying for Sita, but at the same time, in another prakosth (division or section of His pastimes), He is always with Her. He and Sita-devi are never separated.
Now the doubt of Uma was removed. She returned to Lord Siva, who understood internally everything that happened to her and had thus made a vow to remain silent. The demigods showered Sankara with flowers, saying, "Who can take a vow like you?" Uma-devi asked, "What vow have you taken?" He remained silent and did not reply. Somehow she came to know of her husband's vow. From now on he would respect her as his mother. Because she had doubted her guru (Lord Siva), disguised herself as Sita, and lied to her guru when he had asked her if she had tested lord Rama, Lord Siva could no longer accept her as his wife. He entered a trance for thousands of years, and Sati felt severe separation from him. She thought, "Siva has left me. He is treating me like his mother because I took the form of Sita. As long as I am in this body he will not accept me as his wife, so I will have to give up this body."
After some time, Sati's father Daksa, the son of Lord Brahma and great progenitor of the universe, began a sacrifice. Although every sacrifice is intended to please the Supreme Lord Visnu, all the demigods, especially Lord Brahma, Lord Siva and the other principal demigods, are invited and take part. However, Lord Siva was not invited to Daksa's sacrifice. The chaste Sati heard the heavenly denizens, who were flying in the sky, speak about the great sacrifice being performed by her father. She approached her husband and said, "My dear Lord, your father-in-law is now performing a great sacrifice. If you desire, we may also go." Lord Siva warned her not to go, due to her father's enmity and envy towards him - an enmity that had begun long before, in a former Age.Now Lord Siva told Sati, "A woman can go without an invitation to see her guru or her father and mother, but if her father thinks that her husband is his enemy, then she should not go to see him. You know that your father thinks I am his enemy, although I have never considered him as such." Despite her husband's words, Sati was determined to go. She went, but upon her arrival she observed Daksa dishonoring him. She angrily condemned her father and glorified Lord Siva in front of all present. Then, while meditating on Lord Siva's holy lotus feet, she gave up her body in a mystic fire that manifested from her heart. By quitting her body, Sati was able to disconnect herself from her offensive father and transfer herself to another body in order to associate with Lord Siva without that contamination. However, her main motive was to become free from the result of her own offenses, and again be accepted as Lord Siva's beloved wife. In her next life she took birth as Parvati, the daughter of the Himalayas. In that birth she performed austerities for many years and achieved her desired goal. Sati-devi is a pure devotee. She is the Supreme Lord's divine energy, but she was playing a role in order to give lessons to ordinary persons.
So be very careful. You may not have faith in the words of Guru; you may not believe him when he says that the holy name is non-different from Lord Krsna. Sati was not convinced when Lord Siva, who was her guru as well as her husband, said, "Oh, He is the Supreme Personality of Godhead." She thus committed such a serious offense that she had to give up her body as a result.
We must very deeply pay attention to the words of sri gurudeva. If one neglects his words, one is bound to commit an offense. For that kind of person, gurudeva is always silent. He will not say anything to a person who neglects his words. One may hear so many good instructions, but if he has no faith in the words of guru, he will commit offenses. Whenever someone disrespects guru and Vaisnavas, or sees some fault in them, he is actually reflecting the impure feelings of his own eyes and heart onto the Vaisnavas. In reality, guru, Vaisnavas, saints and Lord Siva do not have any faults. To show this again and again, these examples from history are given.


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strathtelegraph October 24, 2019 Music
Review: Hot Chip at The Barrowland Ballroom
By Ryan Harley
Fresh off the back of the success of their critically acclaimed seventh album, A Bath Full of Ecstasy, Hot Chip returned to Glasgow for the third time in just over six months in triumphant style. Every time the London based band come to Glasgow they are full of praise for the city and the music lovers that populate it – and Saturday was no different.
Perhaps it was fate that brought Hot Chip to Glasgow's Barrowland Ballroom on a Saturday night – or just happenstance. A lucky quirk of scheduling, maybe. However, whether luck, fate, or a well-engineered plan to hit one of the best venues in the world at the height of the weekend – the Glasgow crowd could not have been more ready for the band to take the stage, come nine o'clock.
The pace was set by the band's 2015 single 'Huarache Lights' – the thumping bassline of which set the tone for what was to come. From that moment on, the band attacked the setlist with unrelenting and resolute energy.
At times songs melded into one, slipping from song to song seamlessly, tied together by the same pulsating energy that was present in every single song they played.
As is tradition at this point, Hot Chip's covers played a key role in the whole experience of the night. It's always the luck of the draw for audiences as to which they will get. In the past crowds have been treated to Hot Chip's version of Springsteen's 'Dancing in the Dark', or Fleetwood Mac's 'Everywhere'.
Saturday night's roll of the dice brought a cover of 'Sabotage' by the Beastie Boys – a song that Hot Chip have made all but their own at this point. Although slightly out of step with the rest of their songs, 'Sabotage' set the Barrowlands into an absolute frenzy.
Gig-goers may have picked up on a couple of additional covers thrown in for good measure. Tucked neatly into a chorus of 'Night and Day' – almost entirely unnoticeable amongst the frantic pace of the song – was a brief but particularly well received rendition of the proto-punk classic, 'I Was Dancing in the Lesbian Bar' by Jonathan Richman.
For a band that have been on the road for as long as Hot Chip have, it would perhaps make sense that performances such as this could become run of the mill. An exercise in going through the motions, playing a set they play every night – however this was not the case for Hot Chip. Every track was performed with even more driving energy than the last – and the band didn't stop for breath until the closing track was over.
The energy of the whole performance was carried by the energy of the visual experience of the night. In keeping with the design of their latest album, Hot Chip's vibrant and colourful light show and stage design was a sight to be seen. The whole stage; staging, keyboard and (most importantly) the bands' uniforms were bathed top to bottom in colour – all complemented by frontman Alexis Taylor's enormous 3/4 length silver shorts.
As if that wasn't enough, the band followed up their storming Barras set with a terrific DJ set at the city's most revered nightclub, the infamous Sub Club, which Hot Chip seem magnetically drawn to nowadays. Sets in the Jamaica Street venue are becoming a common occurrence for the band – who seemingly find it impossible to play a gig in the city without making a stop there afterwards.
Eclectic and energetic until the very end, Hot Chip upheld their reputation as one of the greatest live bands to come out of the UK in some time. Still at the very top of their game after almost twenty years – Hot Chip are a must see any time they come to town.
Posted in Music and tagged alexis taylor, barrowland ballroom, Barrowlands, hot chip, joe goddard. Bookmark the permalink.
Film Review: Sorry We Missed You
I Forget Where We Were: Five Years On


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by Stephen Burns|Published December 24, 2016
Despite a lopsided loss to the Raiders earlier in the month, the Canucks came into the second weekend in December winners of five of their last six games, looking to build on their recent success with two weekend games.
It started with a showdown against the Pembina Valley Twister, one of the leagues top teams, on Friday, Dec. 9. In a tight-checking, evenly matched game, the Canucks were able to come out on top, largely due to the goal-tending of Tyler Weiss, who picked up his second shutout of the season in the 1-0 victory.
The game's only goal would come at 16:09 of the second period, when Chris Vallance buried his second of the season. Mitchell Lockhart and Graham Philp assisted on the power play marker, which would stand up as the games winning goal.
Weiss stopped all 37 shots he faced for his eighth win of the season.
On Sunday, Dec. 11 the Canucks hosted a team that seemed to have their number this season in the St. Vital Victorias. St. Vital had won the previous two meetings against the Canucks, coming into the game with four players in the top-20 in league scoring.
The Canucks were able to shutdown the Vics high-scoring top-line despite missing some key players due to injury, holding them to just one goal in a 4-1 victory.
The Canucks were all over the Vics in the first period, out-shooting them 14-8. The only goal of the period came off the stick of Chris Vallance during a late power play. It was his second goal in as many games. Nicholas Pierce and Graham Philp were credited with the assists. It was 1-0 Canucks after 20 minutes.
The Vics would tie the game late in the second period and that's where the game stood after 40 minutes, despite the Canucks holding a 24-16 advantage in shots.
The Canucks had a 5-on-3 to start the third and made good on it at Mitchell Lockhart buried one to put the Canucks ahead 2-1. Jeremy Idzikowski and Wyatt Kemball set up Lockhart's team leading 15th of the year. Justin MacKinnon added an empty netter late in the third and Stephane Nukapiak iced it at 18:59 of the final frame after picking the goalies pocket and burying it into a wide open cage. Shane Bigourdon assisted on MacKinnon's 2nd of the year and Devan Lobb and Kole Stockham assisted on Nukapiaks 2nd.
The two wins brings the Canucks record to 15-8-1, and tied for first place in the MMJHL with Pembina Valley.
3 – Mitchell Lockhart: Lockhart scored a goal and had an assist to add to his team-leading point total. He has 30 points in 22 games and is
2 – Tyler Weiss: Weiss stopped all 37 shots he faced against Pembina Valley for his second shutout of the season in a big rebound performance. He's 8-6-1 on the season.
1 – Chris Vallance: Vallance had two power play goals this past weekend and now has three on the year. In total he has 10 points in 20 games played this season.
The Canucks have a relatively light schedule in the next couple of weeks with just two games remaining before the holiday break. On Friday, Dec. 16 they're at Terry Sawchuk Arena to face the River East Royal Knights. On Friday, Dec. 23, they host the Ft. Garry/Ft. Rogue Twins at the St. James Civic Centre to wrap up the unofficial first half of the season.
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