text:
Improving Transparency in Decision Models: Current Issues and Potential Solutions
Posted on 17 November 2019 by davidrcurry
PharmacoEconomics
https://link.springer.com/journal/40273/37/11
Themed Issue : Improving Transparency in Decision Models
Paul Tappenden, J. Jaime Caro
Decision-analytic models have become an essential tool used to inform health technology assessments (HTAs). These models provide a mathematical framework to synthesize data from various sources to support predictions of the economic and health impact of new and existing health technologies. They tend to be complex and are rarely fully validated against external data; yet, use of their forecasts requires trust in their accuracy and lack of bias. Thus, decision makers and other stakeholders want to be able to review their structure, inputs, and assumptions fully, and this necessitates that these models be available and transparent enough to permit adequate review. While most would agree that model transparency is a highly desirable goal, the drive towards its achievement has led to concerns with the disincentives, potential loss of control, harmed intellectual property rights, and additional efforts demanded. In this special issue of PharmacoEconomics we have gathered an impressive and diverse collection of papers addressing many aspects of this important topic in our field…
Cost-consequence analysis of influenza vaccination among the staff of a large teaching hospital in Rome, Italy: A pilot study
[Accessed 16 Nov 2019]
Vittoria Colamesta, Andrea Tamburrano, Andrea Barbara, Andrea Gentili, Daniele Ignazio La Milia, Filippo Berloco, Americo Cicchetti, Daniele Piacentini, Roberta Galluzzi, Sergio Riccardo Mastrodonato, Andrea Cambieri, Walter Ricciardi, Patrizia Laurenti
Research Article | published 14 Nov 2019 PLOS ONE
CRISPR/Cas9 gene editing in the West Nile Virus vector, Culex quinquefasciatus Say
Michelle E. Anderson, Jessica Mavica, Lewis Shackleford, Ilona Flis, Sophia Fochler, Sanjay Basu, Luke Alphey
Culex quinquefasciatus Say is an opportunistic blood feeder with a wide geographic distribution which is also a major vector for a range of diseases of both animals and humans. CRISPR/Cas technologies have been applied to a wide variety of organisms for both applied and basic research purposes. CRISPR/Cas methods open new possibilities for genetic research in non-model organisms of public health importance. In this work we have adapted microinjection techniques commonly used in other mosquito species to Culex quinquefasciatus, and have shown these to be effective at generating homozygous knock-out mutations of a target gene in one generation. This is the first description of the kmo gene and mutant phenotype in this species.
Association between numeracy and self-rated poor health in 33 high- and upper middle- income countries
Volume 127 October 2019
https://www.sciencedirect.com/journal/preventive-medicine/vol/127/suppl/C
Research article Abstract only
Justin Rodgers, Sujay Kakarmath, Vanessa Denis, Marta Encinas-Martin, S.V. Subramanian
:: Numeracy is inversely correlated with poor self-rated health.
:: Associations are robust to adjustment for literacy, education, and sociodemographic factors.
:: Low levels of general literacy may exacerbate the numeracy-health relationship.
:: The numeracy-self-rated health relationship varies by gender, education, and across countries.
:: Interventions aimed at improving both numeracy and literacy may yield greater improvements in population health.
Mitocellular communication: Shaping health and disease
15 November 2019 Vol 366, Issue 6467
http://www.sciencemag.org/current.dtl
Special Issue: Quality control in the cell
By Adrienne Mottis, Sébastien Herzig, Johan Auwerx
Science15 Nov 2019 : 827-832
Cellular RNA surveillance in health and disease
By Sandra L. Wolin, Lynne E. Maquat
Science15 Nov 2019 : 822-827 Restricted Access
Cellular quality control by the ubiquitin-proteasome system and autophagy
By Christian Pohl, Ivan Dikic
Quality control in cell biology
By Stella Hurtley, Gemma Alderton
Science15 Nov 2019 : 816-817 Full Access
Impact of mandatory law on vaccine hesitancy spectrum: The case of measles vaccine catch-up activities in Tuscany, Italy
Volume 37, Issue 49 Pages 7201-7288 (20 November 2019)
https://www.sciencedirect.com/journal/vaccine/vol/37/issue/49
Discussion No access
L. Tavoschi, F. Quattrone, E. De Vita, P.L. Lopalco
Exploring indirect protection associated with influenza immunization – A systematic review of the literature
Review article Open access
Lindsay Friedman, Ariane Renaud, Delaney Hines, Anne Winter, … Bryna F. Warshawsky
The health and economic burden of pertussis in Canada: A microsimulation study
Ashleigh McGirr, David N. Fisman, Ashleigh R. Tuite
From Google Scholar & other sources: Selected Journal Articles, Newsletters, Dissertations, Theses, Commentary
No new digest content identified.
Media/Policy Watch
This watch section is intended to alert readers to substantive news, analysis and opinion from the general media and selected think tanks and similar organizations on vaccines, immunization, global public health and related themes. Media Watch is not intended to be exhaustive, but indicative of themes and issues CVEP is actively tracking. This section will grow from an initial base of newspapers, magazines and blog sources, and is segregated from Journal Watch above which scans the peer-reviewed journal ecology.
We acknowledge the Western/Northern bias in this initial selection of titles and invite suggestions for expanded coverage. We are conservative in our outlook in adding news sources which largely report on primary content we are already covering above. Many electronic media sources have tiered, fee-based subscription models for access. We will provide full-text where content is published without restriction, but most publications require registration and some subscription level.
http://www.theatlantic.com/magazine/
Accessed 16 Nov 2019
[No new, unique, relevant content]
http://www.bbc.co.uk/
http://www.economist.com/
http://www.ft.com/home/uk
http://www.forbes.com/
http://www.foreignaffairs.com/
http://foreignpolicy.com/
The Real Reason to Panic About China's Plague Outbreak
It's not the disease that's worrisome—it's the Chinese government's response to it.
By Laurie Garrett
| November 16, 2019, 1:44 AM
The Chinese government's response to this month's outbreak of plague has been marked by temerity and some fear, which history suggests is entirely appropriate. But not all fear is the same, and Beijing seems to be afraid of the wrong things. Rather than being concerned about the germs and their spread, the government seems mostly motivated by a desire to manage public reaction about the disease. Those efforts, however, have failed—and the public's response is now veering toward a sort of plague-inspired panic that's not at all justified by the facts…
http://www.guardiannews.com/
German parliament approves compulsory measles vaccinations
Bundestag backs law that will fine parents up to €2,500 if children are not inoculated
Germany's parliament has voted to make measles vaccinations compulsory for children, in response to a global rise in cases of the disease.
Parents who refuse to get their children inoculated face fines of up to €2,500 (£2,140) and a likely ban from nursery or school.
The measles protection act will come into force next March, and its introduction is likely to be watched closely by advocates of mandatory immunisation in other countries, including Britain.
The UK health secretary, Matt Hancock, said in September the government was "looking very seriously" at making vaccinations compulsory for state school pupils.
The Bundestag approved the law on Thursday after months of debate, with doctors speaking out both in favour of and against the legislation…
http://www.newyorker.com/
http://www.nytimes.com/
Former Deputy Head of China's Drug Regulator Sentenced to 16 Years in Prison
Wu Zhen, a former deputy head of China's food and drug regulator, was sentenced to 16 years in prison by a Chinese court, state television reported on Friday.
By Reuters Nov. 15
As Swine Fever Fries China Vaccine Sales, Boehringer Rewrites Prescription for Recovery
Germany's Boehringer Ingelheim, the global No. 2 in animal health, is having to rebuild itself in China after a deadly pig disease decimated sales of unrelated mainstay vaccines, bringing write-offs and leaving it facing a three-year slog to recovery.
Think Tanks et al
http://www.brookings.edu/
[No new relevant content]
http://www.cgdev.org/page/press-center
https://www.csis.org/
http://www.cfr.org/
Kaiser Family Foundation
https://www.kff.org/search/?post_type=pre ss-release
Vaccines and Global Health: The Week in Review :: 9 November 2019
Vaccines and Global Health: The Week in Review is a weekly digest summarizing news, events, announcements, peer-reviewed articles and research in the global vaccine ethics and policy space. Content is aggregated from key governmental, NGO, international organization and industry sources, key peer-reviewed journals, and other media channels. This summary proceeds from the broad base of themes and issues monitored by the Center for Vaccine Ethics & Policy in its work: it is not intended to be exhaustive in its coverage. You are viewing the blog version of our weekly digest, typically comprised of between 30 and 40 posts below all dated with the current issue date
.– Request an Email Summary: Vaccines and Global Health : The Week in Review is published as a single email summary, scheduled for release each Saturday evening before midnight (EDT in the U.S.). If you would like to receive the email version, please send your request to david.r.curry@centerforvaccineethicsandpolicy.org.
– pdf version: A pdf of the current issue is available here: Vaccines and Global Health_The Week in Review_9 Nov 2019
– blog edition: comprised of the approx. 35+ entries posted below.
– Twitter: Readers can also follow developments on twitter: @vaxethicspolicy.
– Links: We endeavor to test each link as we incorporate it into any post, but recognize that some links may become "stale" as publications and websites reorganize content over time. We apologize in advance for any links that may not be operative. We believe the contextual information in a given post should allow retrieval, but please contact us as above for assistance if necessary.
Support this knowledge-sharing service: Your financial support helps us cover our costs and to address a current shortfall in our annual operating budget. Click here to donate and thank you in advance for your contribution.
David R. Curry, MS
Center for Vaccine Ethics and Policy
Takeda's Dengue Vaccine Candidate Demonstrates Protection in Children Ages Four to 16 Years, Regardless of Previous Dengue Exposure :: Efficacy of a Tetravalent Dengue Vaccine in Healthy Children and Adolescents :: Takeda Unveils New Dengue Vaccine Manufacturing Plant in Germany
Milestones :: Perspectives :: Research
Takeda's Dengue Vaccine Candidate Demonstrates Protection in Children Ages Four to 16 Years, Regardless of Previous Dengue Exposure
− New England Journal of Medicine publishes primary endpoint analysis from ongoing Phase 3 study of Takeda's dengue vaccine candidate
− Over 20,000 study participants in dengue-endemic areas in Latin America and Asia received two doses of Takeda's dengue vaccine candidate or placebo administered three months apart
− Results demonstrated overall vaccine efficacy of 80.2% (12-month follow-up after second dose) against virologically confirmed dengue; exploratory analyses of secondary endpoints showed 82.2% vaccine efficacy among baseline seropositives and 74.9% vaccine efficacy among baseline seronegatives; the vaccine candidate was generally well tolerated with no important safety risks observed to date
− Formal assessment of secondary efficacy endpoints (18-month follow-up after second dose) will be presented later this year; safety and efficacy will be assessed over a total of four and a half years
… "The results of this first analysis are very encouraging, indicating that the vaccine could potentially provide important public health benefits against dengue fever and hospitalization," said Humberto Reynales, M.D., Ph.D., a lead author of the New England Journal of Medicine paper. "It will be important to further analyze the trial results over time in order to assess the long-term efficacy and safety of the vaccine. If longer follow-up data confirm this initial observation, we are looking at a significant step forward in the global fight against dengue."
"According to the World Health Organization, dengue represents one of the ten biggest global health threats, and it is critical that we have access to a safe and effective vaccine candidate that can reduce the devastating impact dengue fever has in endemic regions," said In-Kyu Yoon, M.D., Senior Advisor, International Vaccine Institute. "Historically, vaccine development against dengue has been challenging, especially for people who haven't previously been exposed to dengue, and these results demonstrate protection from dengue fever, including among many participants without prior dengue."…
::::::
Original Article Free Preview
Efficacy of a Tetravalent Dengue Vaccine in Healthy Children and Adolescents
Shibadas Biswal, M.D., Humberto Reynales, M.D., Ph.D., Xavier Saez-Llorens, M.D., Pio Lopez, M.D., Charissa Borja-Tabora, M.D., Pope Kosalaraksa, M.D., Chukiat Sirivichayakul, M.D., Veerachai Watanaveeradej, M.D., Luis Rivera, M.D., Felix Espinoza, M.D., LakKumar Fernando, M.D., Reynaldo Dietze, M.D., Kleber Luz, M.D., Rivaldo Venâncio da Cunha, M.D., José Jimeno, M.D., Eduardo López-Medina, M.D., Astrid Borkowski, M.D., Ph.D., Manja Brose, M.Sc., Martina Rauscher, Ph.D., Inge LeFevre, M.D., Svetlana Bizjajeva, Ph.D., Lulu Bravo, M.D., and Derek Wallace, M.B., B.S. for the TIDES Study Group*
Dengue, a mosquito-borne viral disease, was designated a World Health Organization top 10 threat to global health in 2019.
We present primary efficacy data from part 1 of an ongoing phase 3 randomized trial of a tetravalent dengue vaccine candidate (TAK-003) in regions of Asia and Latin America in which the disease is endemic. Healthy children and adolescents 4 to 16 years of age were randomly assigned in a 2:1 ratio (stratified according to age category and region) to receive two doses of vaccine or placebo 3 months apart. Participants presenting with febrile illness were tested for virologically confirmed dengue by serotype-specific reverse-transcriptase polymerase chain reaction. The primary end point was overall vaccine efficacy in preventing virologically confirmed dengue caused by any dengue virus serotype.
Of the 20,071 participants who were given at least one dose of vaccine or placebo (safety population), 19,021 (94.8%) received both injections and were included in the per-protocol analysis. The overall vaccine efficacy in the safety population was 80.9% (95% confidence interval [CI], 75.2 to 85.3; 78 cases per 13,380 [0.5 per 100 person-years] in the vaccine group vs. 199 cases per 6687 [2.5 per 100 person-years] in the placebo group). In the per-protocol analyses, vaccine efficacy was 80.2% (95% CI, 73.3 to 85.3; 61 cases of virologically confirmed dengue in the vaccine group vs. 149 cases in the placebo group), with 95.4% efficacy against dengue leading to hospitalization (95% CI, 88.4 to 98.2; 5 hospitalizations in the vaccine group vs. 53 hospitalizations in the placebo group). Planned exploratory analyses involving the 27.7% of the per-protocol population that was seronegative at baseline showed vaccine efficacy of 74.9% (95% CI, 57.0 to 85.4; 20 cases of virologically confirmed dengue in the vaccine group vs. 39 cases in the placebo group). Efficacy trends varied according to serotype. The incidence of serious adverse events was similar in the vaccine group and placebo group (3.1% and 3.8%, respectively).
TAK-003 was efficacious against symptomatic dengue in countries in which the disease is endemic. (Funded by Takeda Vaccines; TIDES ClinicalTrials.gov number, NCT02747927. opens in new tab.)
Takeda Unveils New Dengue Vaccine Manufacturing Plant in Germany
− The manufacturing plant opening marks an important milestone for Takeda's mission to tackle the global threat of dengue
− The site will be utilized for formulation, fill, finish and secondary packaging of Takeda's dengue vaccine candidate
− Takeda's dengue vaccine candidate is currently being evaluated in the pivotal Phase 3 Tetravalent Immunization against Dengue Efficacy Study (TIDES) trial1
SINGEN, Germany–(BUSINESS WIRE)–Takeda Pharmaceutical Company Limited today announced the opening of its new manufacturing plant in Singen, Germany, for its dengue vaccine candidate, TAK-003. The Singen vaccine plant will be utilized for formulation, fill, finish and secondary packaging of the dengue vaccine candidate starting with the packaging line. Takeda invested more than 130 million Euro and will employ up to 200 employees in the vaccine plant…
Nine African countries agree to begin journey towards pooled procurement to increase their access to affordable life-saving vaccines
Brazzaville, 6 November 2019 – Nine middle-income countries in Africa have agreed to work towards pooled procurement mechanisms by first sharing vital information on their vaccine purchasing practices, including the prices they pay and their suppliers. Sharing information and ultimately pooling their orders will better leverage their individual purchasing power and thus strengthen their vaccine security and increase their access to affordable life-saving vaccines.
Their commitment on 1 November to improve in-country and cross-border processes was made following a three-day workshop organized by the World Health Organization (WHO) Regional Office for Africa in Mbabane, Kingdom of Eswatini to address access to safe and affordable vaccines in middle-income countries, where immunization coverage is decreasing.
The workshop brought together the countries that, due to their middle-income status, are not eligible for immunization financing support from Gavi, the Vaccine Alliance (Algeria, Botswana, Cabo Verde, Kingdom of Eswatini, Gabon, Mauritius, Namibia, São Tomé and Príncipe and Seychelles). Participants included officials from the respective health and finance ministries, procurement officials, immunization officers and members of national regulatory authorities for vaccines and medicines.
Despite progress in reducing morbidity and mortality due to vaccine-preventable diseases, around 8.5 million children living in the WHO African Region still do not receive all the basic and necessary vaccines. With many middle-income countries in the region transitioning from donor-supported to domestically funded immunization programmes, access to vaccines remains a challenge due to limited financial resources and to obstacles in accessing a timely and affordable vaccine supply.
A shift towards more strategic approaches to vaccine procurement is critical to improve access to affordable vaccines for middle-income countries in the African Region.
The nine countries agreed on activities to be conducted in common that will work towards a pooled procurement process in the future. These activities include coordinating joint market research, sharing vaccine supplier information and monitoring vaccine prices. By coordinating the informed buying of vaccines, these countries will have greater stability in their vaccine supply as well as increased bargaining power for lower prices.
Five of the countries, those in the regional organization of Small Island Developing States, have already created a single purchasing bloc, which was highlighted during the workshop as an innovative model due to its ability to leverage a better negotiating position and thus achieve reduced prices. Pooling demand can be particularly beneficial to countries with small populations that combine their orders to improve their negotiation terms with suppliers.
Pooled procurement also contributes towards strengthening existing specialized skills for national vaccine procurement and allows for continuous stability in vaccine supply.
The country representatives agreed on collaborating with different models of group purchasing, with all committing to share information and some agreeing to work towards joint price negotiating.
"Pooling vaccine procurement is a major step towards increasing immunization coverage in these countries and the African Region as a whole," said Dr Matshidiso Moeti, WHO Regional Director for Africa. "We must work together to improve vaccine delivery so that all children are protected from preventable diseases. I am heartened to see such strong cooperation between countries to make universal immunization coverage a reality."…
Johnson & Johnson Announces Submission of European Marketing Authorisation Applications for Janssen's Investigational Ebola Vaccine Regimen
Data from multiple preclinical, Phase 1, 2 and 3 studies support applications, which have been granted Accelerated Assessment by European Medicines Agency
NEW BRUNSWICK, N.J.–(BUSINESS WIRE)–Johnson & Johnson today announced that its Janssen Pharmaceutical Companies have submitted Marketing Authorisation Applications (MAAs) to the European Medicines Agency (EMA) seeking licensure for an investigational Ebola vaccine regimen for the prevention of Ebola Virus Disease (EVD) caused by Zaire ebolavirus species. Two MAAs have been submitted in parallel supporting each vaccine in the two-dose regimen (Ad26.ZEBOV, MVA-BN-Filo). In September 2019, the EMA's Committee for Medicinal Products for Human Use (CHMP) granted an Accelerated Assessment for these applications.
"It is vital that we ensure global preparedness for Ebola given that the world's largest Ebola outbreaks have taken place in the last six years alone, with the latest currently underway in the Democratic Republic of the Congo (DRC)," said Paul Stoffels, M.D., Vice Chairman of the Executive Committee and Chief Scientific Officer of Johnson & Johnson. "With an understanding that vaccines have an important role to play in countering this epidemic threat, we look forward to the EMA's review of our applications for licensure."
The vaccine regimen includes Ad26.ZEBOV as the first dose, which is based on Janssen's AdVac® technology, and MVA-BN-Filo as the second dose, which is based on Bavarian Nordic's MVA-BN® technology and is administered approximately eight weeks later. The MAAs are supported by data from Phase 1, 2 and 3 clinical studies evaluating the safety and immunogenicity of the vaccine regimen in adults and children1-7, preclinical studies, and immunobridging analyses. To date, more than 6,500 volunteers across the U.S., Europe and Africa have participated in over 10 clinical studies of the Janssen vaccine.
"Our goal is to deliver a vaccine that can be used both in response to Ebola outbreaks, and also more proactively as a prophylactic tool to help countries protect their populations," said Johan Van Hoof, M.D., Global Therapeutic Area Head, Vaccines, and Managing Director, Janssen Vaccines & Prevention B.V., Janssen Pharmaceutica N.V. "We are grateful to our many global partners who have helped us reach this important stage of development."…
Ebola – DRC+
Public Health Emergency of International Concern (PHEIC)
Ebola Outbreak in DRC 66: 05 November 2019
1. Situation update
In the past week, from 28 October to 3 November 2019, 10 new confirmed Ebola virus disease (EVD) cases were reported from five health zones in two affected provinces in the Democratic Republic of the Congo. Though the number of new confirmed EVD cases reported is lower this week, compared to the 20 cases reported last week, security issues and poor access continue to slow response activities in certain health zones. This can prevent the detection of cases in these hard to reach areas.
Violence this week in Lwemba Health Area in the Mandima Health Zone, caused the death of an Ebola response community health worker, and left his spouse critically injured with multiple wounds. WHO and partners condemned the attack, adding that acts of violence against individuals involved with the response are unacceptable and compromise the ability of health workers to provide assistance to communities impacted by the devastating effects of Ebola…
Implementation of ring vaccination protocol
As of 3 November 2019, 246,824 people at risk have consented to and received the rVSV-ZEBOV-GP Ebola Vaccine with 2,865 vaccinated in the past week
Polio this week as of 06 November 2019
:: The GPEI is pleased to announce that the UK Government has confirmed its commitment to eradicating polio by pledging a £400 million contribution for the next four years, which will help vaccinate more than 400 million children a year. Read more on the remarkable announcement.
:: In Pakistan, a circulating vaccine-derived poliovirus type 2 has been confirmed. A detailed investigation into the origin of the outbreak is ongoing, with circulation confirmed in a geographically-limited area, and outbreak response is being planned and implemented.
:: Are you an immunization expert interested in serving on the Strategic Advisory Group of Experts (SAGE) on polio? The call for nominations for membership on the working group has now been issued, targeting individuals to submit their nominations.
: Want to know the future of polio eradication efforts in Africa? Then stay tuned for a Facebook live interview with Dr Pascal Mkanda, chief polio expert in the WHO African Region, on 08 November 2019 at 10:00am, West Africa Time.
Summary of new viruses this week (AFP cases and ES positives):
:: Afghanistan— one WPV1 case and one WPV1 positive environmental sample;
:: Pakistan— three WPV1 cases and 19 WPV1-positive environmental samples;
:: Angola— 7 cVDPV2 cases and one cVDPV2 positive environmental sample;
:: Central African Republic— one cVDPV2 case and one cVDPV2 positive environmental sample;
:: Cote d'Ivoire one cVDPV2 positive environmental sample;
:: Ghana two cVDPV2 cases;
:: Philippines— one cVDPV2 case and four cVDPV2 positive environmental samples.
UK aid to help vaccinate more than 400 million children a year against polio
Press release Published 5 November 2019
International Development Secretary Alok Sharma has pledged new UK aid support to help vaccinate more than 400 million children a year against polio.
:: UK support will help vaccinate more than 750 children a minute against polio in developing countries around the world
:: The UK package of up to £400 million will help support 20 million health workers and volunteers
:: Polio was wiped out in UK in the 1980s, but three countries – Pakistan, Afghanistan and Nigeria – are still not officially wild polio free
WHO has posted a refreshed emergencies page which presents an updated listing of Grade 3,2,1 emergencies as below.
WHO Grade 3 Emergencies [to 9 Nov 2019]
:: Ebola Outbreak in DRC 66: 05 November 2019
Mozambique floods – No new digest announcements identified
Nigeria – No new digest announcements identified
Somalia – No new digest announcements identified
South Sudan – No new digest announcements identified
Syrian Arab Republic – No new digest announcements identified
Yemen – No new digest announcements identified
:: Yellow fever campaign launches in Khartoum State as final phase of countrywide immunization drive 7 November 2019
:: WHO scales up cholera vigilance in Khartoum, Sudan 5 November 2019
Afghanistan – No new digest announcements identified
Angola – No new digest announcements identified
Burkina Faso [in French] – No new digest announcements identified
Burundi – No new digest announcements identified
Cameroon – No new digest announcements identified
Central African Republic – No new digest announcements identified
Ethiopia – No new digest announcements identified
HIV in Pakistan – No new digest announcements identified
Iran floods 2019 – No new digest announcements identified
Iraq – No new digest announcements identified
Libya – No new digest announcements identified
Malawi floods – No new digest announcements identified
Measles in Europe – No new digest announcements identified
MERS-CoV – No new digest announcements identified
Myanmar – No new digest announcements identified
Niger – No new digest announcements identified
occupied Palestinian territory – No new digest announcements identified
Ukraine – No new digest announcements identified
Zimbabwe – No new digest announcements identified
Chad – No new digest announcements identified
Djibouti – No new digest announcements identified
Kenya – No new digest announcements identified
Mali – No new digest announcements identified
Namibia – viral hepatitis – No new digest announcements identified
Tanzania – No new digest announcements identified
UN OCHA – L3 Emergencies
The UN and its humanitarian partners are currently responding to three 'L3' emergencies. This is the global humanitarian system's classification for the response to the most severe, large-scale humanitarian crises.
:: Syria ǀ Flash Update #11, Humanitarian impact of the military operation in north-eastern Syria, 29 – 31 October 2019 [EN/AR]
UN OCHA – Corporate Emergencies
When the USG/ERC declares a Corporate Emergency Response, all OCHA offices, branches and sections provide their full support to response activities both at HQ and in the field.
Ebola in the DRC has bene added as a OCHA "Corporate Emergency" this week:
CYCLONE IDAI and Kenneth
:: 08 Nov 2019 South Sudan: CERF allocates up to $15 million for flooding response
EBOLA OUTBREAK IN THE DRC – No new digest announcements identified
WHO & Regional Offices [to 9 Nov 2019]
8 November 2019 News release
WHO aids flood-hit populations across Africa and the Eastern Mediterranean Region
Well over a million people have been affected in some of the worst-hit countries of Benin, Cameroon, Central African Republic, Somalia, South Sudan and Yemen.
Weekly Epidemiological Record, 8 November 2019, vol. 94, 45 (pp. 513–524)
:: Elimination of human onchocerciasis: progress report, 2018–2019
WHO Regional Offices
Selected Press Releases, Announcements
WHO African Region AFRO
:: Nine African countries agree to begin journey towards pooled procurement to increase their access to affordable life-saving vaccines 06 November 2019
[See Milestones above for detail]
WHO Region of the Americas PAHO
:: Municipalities from Brazil, Guatemala, and Honduras receive the 2019 PAHO Malaria Champions Award (11/06/2019)
:: Improving adolescent health in the Caribbean (11/06/2019)
:: Guyana launches mass drug administration campaign to intensify efforts to end Lymphatic Filariasis (11/06/2019)
WHO South-East Asia Region SEARO
WHO European Region EURO
WHO Eastern Mediterranean Region EMRO
:: ECHO and WHO partnership meets critical trauma needs in Yemen 6 November 2019
CDC/ACIP [to 9 Nov 2019]
http://www.cdc.gov/media/index.html
https://www.cdc.gov/vaccines/acip/index.html
CDC Telebriefing: New CDC Antibiotic Resistance Threats Report shows infection prevention is working but continued action is needed to protect all people
Africa CDC [to 9 Nov 2019]
http://www.africacdc.org/
China CDC
http://www.chinacdc.cn/en/
National Health Commission of the People's Republic of China
http://en.nhc.gov.cn/
Selected Updates and Press Releases
Paul G. Allen Frontiers Group [to 9 Nov 2019]
https://alleninstitute.org/what-we-do/frontiers-group/news-press/
The Paul G. Allen Frontiers Group Names New Allen Distinguished Investigators
Five new awardees will embark on stem cell and tissue research with the potential to impact human health"
Samantha Morris, Ph.D.
Joshua Rabinowitz, Ph.D.
Clive Svendsen, Ph.D.
Cedars-Sinai
Savas Tay, Ph.D.
James Wells, Ph.D.
Cincinnati Children's Hospital Medical Center
BMGF – Gates Foundation [to 9 Nov 2019]
http://www.gatesfoundation.org/Media-Center/Press-Releases
Bill & Melinda Gates Medical Research Institute [to 9 Nov 2019]
https://www.gatesmri.org/
The Bill & Melinda Gates Medical Research Institute is a non-profit biotech organization. Our mission is to develop products to fight malaria, tuberculosis, and diarrheal diseases—three major causes of mortality, poverty, and inequality in developing countries. The world has unprecedented scientific tools at its disposal; now is the time to use them to save the lives of the world's poorest people
CARB-X [to 9 Nov 2019]
https://carb-x.org/
CARB-X is a non-profit public-private partnership dedicated to accelerating antibacterial research to tackle the global rising threat of drug-resistant bacteria.
CARB-X funds Techulon to support the development of innovative nano therapeutics capable of killing drug-resistant bacteria by precisely targeting essential genes
Techulon project is the 50th project funded by CARB-X since it was launched in 2016
(BOSTON, MA) – CARB-X is awarding Techulon Inc., located in the Virginia Tech Corporate Research Center in Blacksburg, VA, USA, up to $785,000 in non-dilutive funding to develop a new class of antimicrobial that would kill drug-resistant bacteria by targeting specific genes critical to the bacteria's survival. The CARB-X award supports preclinical hit-to-lead development of Techulon's drug candidates targeting Acinetobacter baumannii and Pseudomonas aeruginosa, two superbugs that have been identified by the World Health Organization (WHO) as 'priority pathogens' posing the greatest threat to global health and by the US Centers for Disease Control and Prevention (CDC) as 'serious threats' to human health.
The Techulon project is the 50th innovative antibacterial early development project funded by CARB-X, established in July 2016. To date, CARB-X has invested more than $150 million in non-dilutive funding to accelerate the development of antibiotics, vaccines, diagnostics and other life-saving products to address drug-resistant bacteria, with additional funds committed if projects achieve certain milestones. The CARB-X portfolio has 31 active projects in five countries…
CEPI – Coalition for Epidemic Preparedness Innovations [to 9 Nov 2019]
http://cepi.net/
Clinton Health Access Initiative, Inc. (CHAI) [to 9 Nov 2019]
https://clintonhealthaccess.org/about/
EDCTP [to 9 Nov 2019]
http://www.edctp.org/
The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials
Emory Vaccine Center [to 9 Nov 2019]
http://www.vaccines.emory.edu/
European Medicines Agency [to 9 Nov 2019]
http://www.ema.europa.eu/ema/
European Vaccine Initiative [to 9 Nov 2019]
http://www.euvaccine.eu/news-events
FDA [to 9 Nov 2019]
https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/default.htm
November 8, 2019 – FDA approves first therapy to treat patients with rare blood disorder
Today the U.S. Food and Drug Administration granted approval to Reblozyl (luspatercept–aamt) for the treatment of anemia (lack of red blood cells) in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions…
November 6, 2019 – Statement on the agency's efforts to protect patients through postmarket drug safety surveillance practices
… The Cures Act included a new requirement that the FDA make our best practices for drug safety surveillance publicly available on the web. Following the passage of the Cures Act we posted a statement announcing the risk-based principles we use for postmarket safety surveillance. Today, we're announcing the availability of our draft document, "Best Practices in Drug and Biological Product Postmarket Safety Surveillance for FDA Staff," which expands upon those principles. This draft best practice document outlines our approach for timely postmarket analyses of drugs and biologics, and includes a high-level overview of tools, methods, and signal detection and evaluation activities, using varied data sources, for drug safety surveillance to provide a broader context and a general overview of our overarching effort and commitment in this area….
Fondation Merieux [to 9 Nov 2019]
http://www.fondation-merieux.org/
December 3 – 4, 2019 – Geneva (Switzerland)
Mérieux Foundation co-organized event
6th GTFCC Working Group on Oral Cholera Vaccine
20 – 22 Jan 2020
Dengue pre-vaccination screening strategies workshop
Les Pensières Center for Global Health, Veyrier-du-Lac (France)
Gavi [to 9 Nov 2019]
https://www.gavi.org/
Democratic Republic of Congo launches major push against measles, cholera, and rotavirus
Measles follow-up immunisation campaign, emergency oral cholera vaccine campaign, and rotavirus vaccine introduction to protect millions against combination of epidemics.
GHIT Fund [to 9 Nov 2019]
https://www.ghitfund.org/newsroom/press
GHIT was set up in 2012 with the aim of developing new tools to tackle infectious diseases that No new digest content identified.
Global Fund [to 9 Nov 2019]
https://www.theglobalfund.org/en/news/
Funding Model
Updated Documents and Technical Guidance for Applicants
Updated resources for applicants are now available on the Global Fund website in preparation for the 2020-2022 funding period.
These documents have been updated:
:: Funding requests forms and instructions on the Funding Request Applications page
:: Programmatic gap tables on the Funding Request Applications page
:: Funding Landscape Table download in English | Español | Français
:: Modular Framework Handbook download in English | Español | Français
Applicants can familiarize themselves with the following core technical investment documents:
:: HIV Information Note download in English | Español | Français
:: Tuberculosis Information Note download in English | Español | Français
:: Malaria Information Note download in English | Español | Français
:: Building Resilient and Sustainable Systems for Health through Global Fund Investments Information Note download in English | Español | Français
Hilleman Laboratories [to 9 Nov 2019]
http://www.hillemanlabs.org/
Human Vaccines Project [to 9 Nov 2019]
http://www.humanvaccinesproject.org/media/press-releases/
IAVI [to 9 Nov 2019]
https://www.iavi.org/newsroom
International Coalition of Medicines Regulatory Authorities [ICMRA]
http://www.icmra.info/drupal/en/news
Selected Statements, Press Releases, Research
International Generic and Biosimilar Medicines Association [IGBA]
https://www.igbamedicines.org/
http://www.iffim.org/library/news/press-releases/
IFRC [to 9 Nov 2019]
http://media.ifrc.org/ifrc/news/press-releases/
Mozambique: Thousands at risk of disease and malnutrition as rainy season begins
Beira/Geneva, 8 November 2019—More than half a year since cyclones Idai and Kenneth hit Mozambique, thousands of people are at risk of disease outbreaks and worsening food insecurity during the coming rainy season. Food insecurity is expected to affec …
Philippines: Thousands in need of humanitarian assistance after Mindanao earthquakes
More than 180,000 people are affected with many families requiring humanitarian assistance after a series of powerful earthquakes, struck Cotabato province in Mindanao, Philippines.
IVAC [to 9 Nov 2019]
https://www.jhsph.edu/research/centers-and-institutes/ivac/index.html
10 Years of Progress in Global Immunization Programs Celebration
The International Vaccine Access Center (IVAC) will be celebrating its 10th anniversary on December 9, 2019 with an event at the Johns Hopkins Bloomberg School of Public Health featuring Executive Director Dr. Bill Moss, Senior Advisor Mathu Santosham, and a keynote address by Dr. Orin Levine, Director of Global Delivery Programs at the Bill and Melinda Gates Foundation and the original founder of IVAC. Comments by Dr. Kate O'Brien, IVAC's immediate past Executive Director and current Director of Immunization, Vaccines and
Biologicals at the World Health Organization, will open the event.
IVI [to 9 Nov 2019]
http://www.ivi.int/
Selected IVI News & Announcements
IVI acquires GCLP certification from Korean Ministry of Food and Drug Safety
Institute expected to increase contributions to vaccine development activities worldwide
JEE Alliance [to 9 Nov 2019]
https://www.jeealliance.org/
Selected News and Events
MSF/Médecins Sans Frontières [to 9 Nov 2019]
http://www.msf.org/
Latest [Selected Announcements]
More than 5,000 patients treated during MSF respons…
Project Update 8 Nov 2019
DRC Ebola outbreaks
Crisis update – November 2019
Crisis Update 5 Nov 2019
Four questions on the malaria outbreak in western Sudan
Interview 4 Nov 2019
National Vaccine Program Office – U.S. HHS [to 9 Nov 2019]
https://www.hhs.gov/vaccines/about/index.html
NVAC 2020 Meetings
February 13-14, 2020 NVAC Meeting
June 9-10, 2020 NVAC Meeting
September 23-24, 2020 Meeting (Virtual)
NIH [to 9 Nov 2019]
http://www.nih.gov/news-events/news-releases
Selected News Releases
Study vaccine protects monkeys against four types of hemorrhagic fever viruses
November 8, 2019 — The vaccine provided protection from Ebola virus, Sudan virus, Marburg virus and Lassa virus.
PATH [to 9 Nov 2019]
https://www.path.org/media-center/
Selected Announcements
November 7, 2019 by PATH
Blood pressure check with your manicure?
Communities for Healthy Hearts in Vietnam uses local volunteers and businesses to help people with hypertension discover their condition and take steps to manage it
Sabin Vaccine Institute [to 9 Nov 2019]
http://www.sabin.org/updates/pressreleases
UNAIDS [to 9 Nov 2019]
http://www.unaids.org/en
Selected Press Releases/Reports/Statements
Confronting the link between HIV and gender-based violence in Jamaica
Worldwide, more than half of new HIV infections now among key populations and their sexual partners
… Key populations make up a small proportion of the general population, but they are at extremely high risk of acquiring HIV infection. Available data suggest that the risk of HIV acquisition among gay men and other men who have sex with men was 22 times higher in 2018 than it was among all adult men. Similarly, the risk of acquiring HIV for people who inject drugs was 22 times higher than for people who do not inject drugs, 21 times higher for sex workers than adults aged 15–49 years and 12 times higher for transgender women than adults aged 15–49 years….
UNICEF [to 9 Nov 2019]
https://www.unicef.org/media/press-releases
Selected Statements, Press Releases, Reports
60,000 young refugees and migrants who arrived in Italy alone need ongoing support as they transition to adulthood – UN Agencies
Key challenges include discrimination, difficulty finding work, administrative bottlenecks and lack of legal information
200,000 children affected as heavy flooding in Somalia brings increased risk of malnutrition and disease outbreak
UNICEF and partners working to meet urgent needs of most vulnerable children
Vaccination Acceptance Research Network (VARN) [to 9 Nov 2019]
https://vaccineacceptance.org/news.html#header1-2r
Vaccine Confidence Project [to 9 Nov 2019]
http://www.vaccineconfidence.org/
Vaccine Education Center – Children's Hospital of Philadelphia [to 9 Nov 2019]
http://www.chop.edu/centers-programs/vaccine-education-center
Wellcome Trust [to 9 Nov 2019]
https://wellcome.ac.uk/news
News | 8 November 2019
We are carbon off-setting our travel
Twitter | 7 November 2019
A new science for epidemics must include these 7 disciplines (opens in a new tab)
Opinion | 5 November 2019
It's time to rethink the way we talk about one of the most urgent threats to our health
by Jeremy Farrar
Tackling big health challenges is dependent on science and innovation, but also on the public understanding and engaging with them.
7 things manifesto writers should know about science
by Martin Smith
The Wistar Institute [to 9 Nov 2019]
https://www.wistar.org/news/press-releases
Press Release Nov. 8, 2019
Synthetic DNA Technology Applied as a Novel Strategy for Delivery of Anti-HIV Antibodies
Synthetic DNA-encoded monoclonal antibodies (DMAbs) allow for in vivo production of broadly neutralizing antibodies in preclinical studies.
World Organisation for Animal Health (OIE) [to 9 Nov 2019]
http://www.oie.int/en/for-the-media/press-releases/2019/
'United Against Rabies' collaboration celebrates one year of progress towards zero human rabies deaths by 2030
Since the launch of 'Zero by 30' in 2018, the United Against Rabies collaboration has made progress to empower, engage and enable countries to reach the rabies elimination goal by 2030. Released today on World Rabies Day, the first annual progress report describes the incremental, collaborative impact of the four partners[1] in promoting the One Health approach[2] and achieving the three objectives of the Global Strategic Plan.
ARM [Alliance for Regenerative Medicine] [to 9 Nov 2019]
https://alliancerm.org/press-releases/
The Alliance for Regenerative Medicine Releases Q3 2019 Sector Report, Highlighting Industry Trends and Metrics
Highlighted findings from the Q3 2019 data report include:
:: Globally, companies active in gene and cell therapies and other regenerative medicines raised nearly $2.6 billion in the third quarter of 2019, bringing the year-to-date total financings to more than $7.4 billion. The report also includes financial data broken out by technology type and financing type.
:: There were 1,052 clinical trials underway worldwide at the close of the third quarter of 2019, with more than 60% of those in oncology and 5% in musculoskeletal disorders and central nervous system disorders. The report also includes figures on clinical trials by phase and indication, as well as by technology type.
BIO [to 9 Nov 2019]
https://www.bio.org/insights/press-release
DCVMN – Developing Country Vaccine Manufacturers Network [to 9 Nov 2019]
http://www.dcvmn.org/
IFPMA [to 9 Nov 2019]
http://www.ifpma.org/resources/news-releases/
Selected Press Releases, Statements, Publications
PhRMA [to 9 Nov 2019]
http://www.phrma.org/
Selected Press Releases, Statements
Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focu-s on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.
If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org
A childhood immunization education program for parents delivered during late pregnancy and one-month postpartum: a randomized controlled trial
BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content
Improved immunization rates have reduced the incidence of vaccine-preventable diseases (VPDs) in advanced nations. Japan's unique vaccination system classifies vaccines into routine vaccines ostensibly require…
Authors: Hiroko Otsuka-Ono, Narumi Hori, Hiroshi Ohta, Yukari Uemura and Kiyoko Kamibeppu
Citation: BMC Health Services Research 2019 19:798
Published on: 5 November 2019
Health professionals' acceptance and willingness to pay for hepatitis B virus vaccination in Gondar City Administration governmental health institutions, Northwest Ethiopia
Hepatitis B virus (HBV) infection is a global public health problem. The burden of the disease is high in low and middle income countries like Ethiopia. However, for highly vulnerable groups such as health pro…
Authors: Siwule Abiye, Mezgebu Yitayal, Giziew Abere and Asefa Adimasu
Content type: Research article
Mumps: MMR vaccination and genetic diversity of mumps virus, 2007–2011 in Catalonia, Spain
BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 9 Nov 2019)
Mumps is a vaccine-preventable disease but outbreaks have been reported in persons vaccinated with two doses of MMR vaccine.
Authors: Irene Barrabeig, Andrés Antón, Núria Torner, Tomàs Pumarola, Josep Costa and Àngela Domínguez
Citation: BMC Infectious Diseases 2019 19:954
What do patients with unmet medical needs want? A qualitative study of patients' views and experiences with expanded access to unapproved, investigational treatments in the Netherlands
http://www.biomedcentral.com/bmcmedethics/content
Patients with unmet medical needs sometimes resort to non-standard treatment options, including the use of unapproved, investigational drugs in the context of clinical trials, compassionate use or named-patient programs. The views and experiences of patients with unmet medical needs regarding unapproved, investigational drugs have not yet been examined empirically.
Authors: Eline M. Bunnik and Nikkie Aarts
mHealth communication to strengthen postnatal care in rural areas: a systematic review
BMC Pregnancy and Childbirth
http://www.biomedcentral.com/bmcpregnancychildbirth/content
Postnatal care (PNC) in rural areas is characterised by low uptake, with possible effect on maternal and neonatal mortality rates. Mobile health (mHealth) communication has been proposed to promote the uptake …
Authors: Florence Mbuthia, Marianne Reid and Annali Fichardt
Citation: BMC Pregnancy and Childbirth 2019 19:406
Immunity to rubella: an Italian retrospective cohort study
http://bmcpublichealth.biomedcentral.com/articles
International guidelines recommend that healthcare workers (HCWs) have presumptive evidence of immunity to rubella and that susceptible HCWs and doubt cases receive two doses of the MMR vaccine. However, a sma…
Authors: Francesco Paolo Bianchi, Sara De Nitto, Pasquale Stefanizzi, Angela Maria Vittoria Larocca, Cinzia Annatea Germinario and Silvio Tafuri
Citation: BMC Public Health 2019 19:1490
The fog of genetics: what is known, unknown and unknowable in the genetics of complex traits and diseases
Volume 20 Issue 11 5 November 2019
https://www.embopress.org/toc/14693178/current
Opinion 21 October 2019
João Pedro de Magalhães, Jingwei Wang
A major task for genetics is searching for genetic variants associated with disease. But we may well be missing a large number of "unknown unknown" alleles in the "fog of genetics".
Preparing scientists for a visual future : Visualization is a powerful tool for research and communication but requires training and support
Science & Society 14 October 2019
Shraddha Nayak. Janet H Iwasa
The increasing complexity of biological data along with the need to communicate results requires visualization. It requires more training and support though to help scientists create efficient visual representations of their work.
Making AMR history: a call to action
Global Health Action
Volume 12, 2019 Supp 1
https://www.tandfonline.com/toc/zgha20/12/sup1?nav=tocList
Antimicrobial Resistance – Issue In Progress
Tedros Adhanom Ghebreyesus
Article: 1638144
Published online: 11 Jul 2019
Knowing antimicrobial resistance in practice: a multi-country qualitative study with human and animal healthcare professionals
Maddy Pearson & Clare Chandler
Measles, Mumps, And Communion: A Vision For Vaccine Policy
Health Affairs
Vol. 38, No. 11 November 2019
https://www.healthaffairs.org/toc/hlthaff/current
Household Costs, Food & More
Narrative Matters Ethics
Joshua T. B. Williams
A pediatrician offers a vision for vaccine policy that promotes public health while respecting religious beliefs.
A Professional Standard for Informed Consent for Stem Cell Therapies
November 5, 2019, Vol 322, No. 17, Pages 1625-1728
http://jama.jamanetwork.com/issue.aspx
Jeremy Sugarman, MD, MPH, MA; Roger A. Barker, MRCP, PhD; R. Alta Charo, JD
JAMA. 2019;322(17):1651-1652. doi:10.1001/jama.2019.11290
This Viewpoint summarizes recommendations from an International Society for Stem Cell Research task force charged with developing professional standards of patient consent for stem cell–based interventions offered outside a clinical trial given the spread of unregulated stem cell clinics offering unproven therapies.
Government Role in Regulating Vaccine Misinformation on Social Media Platforms
November 2019, Vol 173, No. 11, Pages 1007-1115
http://archpedi.jamanetwork.com/issue.aspx
Y. Tony Yang, ScD, LLM, MPH; David A. Broniatowski, PhD; Dorit Rubinstein Reiss, PhD
JAMA Pediatr. 2019;173(11):1011-1012. doi:10.1001/jamapediatrics.2019.2838
This Viewpoint discusses the challenges of balancing free speech against harms caused by vaccine misinformation on social media platforms and what the government's role could potentially be in combating misinformation.
Prevalence of Immunodeficiency in Children With Invasive Pneumococcal Disease in the Pneumococcal Vaccine EraA Systematic Review
Coen Butters, BMed, DCH; Linny Kimly Phuong, BPharm(Hons), MBBS, DCH, MPH; Theresa Cole, BM, MRCPCH, PhD, FRACP; et al.
This systematic review of 17 studies assesses risk of primary immunodeficiency in children presenting with invasive pneumococcal disease with no other predisposing condition.
Public Knowledge of Human Papillomavirus and Receipt of Vaccination Recommendations
Research Letter
Ryan Suk, MS; Jane R. Montealegre, PhD; Gizem S. Nemutlu, PhD; et al.
This cross-sectional survey study assesses knowledge of human papillomavirus by age and sex.
Interdisciplinary research in public health: the 'why' and the 'how'
Journal of Epidemiology & Community Health
December 2019 – Volume 73 – 12
https://jech.bmj.com/content/73/12
(8 October, 2019)
Joelle Kivits, Laetitia Ricci, Laetitia Minary
Immunogenicity and Reactogenicity of 13-Valent Pneumococcal Conjugate Vaccine Among Infants, Toddlers, and Children in Western Burkina Faso: Results From a Clinical Trial of Alternative Immunization Schedules
Journal of the Pediatric Infectious Diseases Society (JPIDS)
Volume 8, Issue 5, November 2019
https://academic.oup.com/jpids/issue
Jennifer C Moïsi, Seydou Yaro, Sita S Kroman, Clarisse Gouem, Dramane Bayane …
J Pediatric Infect Dis Soc, Volume 8, Issue 5, November 2019, Pages 422–432, https://doi.org/10.1093/jpids/piy075
PCV13 has a satisfactory reactogenicity and immunogenicity profile when administered to infants, toddlers, and children according to alternative immunization schedules in Burkina Faso.
ICPD at 25 years: time to expand the agenda
Nov 09, 2019 Volume 394 Number 10210 p1685-1778, e35
https://www.thelancet.com/journals/lancet/issue/current
In September, 1994, 11 000 delegates from governments, the UN, non-governmental organisations, and media gathered in Cairo, Egypt, for the International Conference on Population and Development (ICPD). This event was transformative for the reproductive health and rights community. The global consensus that emerged in Cairo—manifested in the ICPD Programme of Action adopted by 179 countries—shifted the focus of the development agenda away from demographics towards sexual and reproductive health and wellbeing, individual rights, and gender equality. 25 years on, the community will reconvene in Nairobi, Kenya, on Nov 12–14, to review progress and accelerate the implementation of the ICPD Programme of Action…
Nature at 150: evidence in pursuit of truth
Volume 575 Issue 7781, 7 November 2019
http://www.nature.com/nature/current_issue.html
Editorial | 06 November 2019
A century and a half has seen momentous changes in science. But evidence and transparency are more important than ever before.
… In other respects, Nature now is just the same as it was at the start. We will continue in our mission to stand up for research, serve the global research community and communicate the results of science around the world. We will strive to hold to account those in positions of responsibility in research, policy and industry, and to continue to advocate for fewer unintended harmful consequences of research for people and the planet.
Research, science, knowledge, scholarship — however we might choose to characterize the marshalling of evidence in the pursuit of truth — the values we hold are more important than ever before.
Immunization: vital progress, unfinished agenda
Review Article | 06 November 2019
An overview of the effects of vaccines on global morbidity and mortality, vaccine safety issues, and the hurdles involved in proceeding from vaccine discovery to successful implementation.
Peter Piot, Heidi J. Larson[…] & Beate Kampmann
Vaccination against infectious diseases has changed the future of the human species, saving millions of lives every year, both children and adults, and providing major benefits to society as a whole. Here we show, however, that national and sub-national coverage of vaccination varies greatly and major unmet needs persist. Although scientific progress opens exciting perspectives in terms of new vaccines, the pathway from discovery to sustainable implementation can be long and difficult, from the financing, development and licensing to programme implementation and public acceptance. Immunization is one of the best investments in health and should remain a priority for research, industry, public health and society.
A new twenty-first century science for effective epidemic response
Juliet Bedford, Jeremy Farrar[…] & John Nkengasong
With rapidly changing ecology, urbanization, climate change, increased travel and fragile public health systems, epidemics will become more frequent, more complex and harder to prevent and contain. Here we argue that our concept of epidemics must evolve from crisis response during discrete outbreaks to an integrated cycle of preparation, response and recovery. This is an opportunity to combine knowledge and skills from all over the world—especially at-risk and affected communities. Many disciplines need to be integrated, including not only epidemiology but also social sciences, research and development, diplomacy, logistics and crisis management. This requires a new approach to training tomorrow's leaders in epidemic prevention and response.
The next biotech superpower
Volume 37 Issue 11, November 2019
https://www.nature.com/nbt/volumes/37/issues/11
China is set to challenge the pre-eminence of the US drug market. If it can address gaps in its R&D ecosystem and clinical infrastructure, it may even become a home for biotech innovators.
PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels
https://www.nature.com/ng/volumes/51/issues/11
Comment | 01 November 2019
A fundamental problem in rare-disease diagnostics is the lack of consensus as to which genes have sufficient evidence to attribute causation. To address this issue, we have created PanelApp ( https://panelapp.genomicsengland.co.uk ), a publicly available knowledge base of curated virtual gene panels.
Antonio Rueda Martin, Eleanor Williams[…] & Ellen M. McDonagh
A framework for tiered informed consent for health genomic research in Africa
Comment | 28 October 2019
A generic framework for providing participant information and implementing a tiered consent process for health genomic research in Africa can help to harness global health benefits from sharing and meta-analysis of African genomic data while simultaneously respecting and upholding the autonomy and individual choices of African research participants.
Victoria Nembaware, Katherine Johnston[…] & Nicki Tiffin


AMERICAN EAGLE FEDERAL CREDIT UNION is a community credit union that has 16 branches with approximately 98947 members serving the greater Hartford county area. The credit union first opened 84 years ago in 1935 and is a member of the Federal Home Loan Banks (FHLB). Now with more than $1325 million in assets, AMERICAN EAGLE FEDERAL CREDIT UNION employs about 238 people offering various banking and financial related services to its members.


Safe Steps family violence response centre is the State-wide family violence crisis service and main point of call for women and children in Victoria who are in crisis and experiencing family violence. Members may be aware that DHHS commissioned a review of safe steps following ASU concerns being raised about alarming industrial and practice issues with the agency directly, relevant State Government MPs and Family Safety Victoria.
The Review outcomes are now being acted on by the Safe Step's Board and DHHS. The ASU is pleased to share that the concerns raised by ASU members have been heard and that in early October senior leadership, including CEO, Annette Gillespie, have been removed. See Guardian Article.
The ASU is keeping a watchful eye on what happens next. The Board and new leadership have an opportunity to fix the issues and to ensure that women and children are supported by a workforce that is respected, resourced and supported to do this important work.
Well done ASU for raising concerns about the "toxic culture" in FSV! As a community sector employee, I find that we're often subjected to the toxic culture of sections of DHHS through bullying by senior public servants, pedantic and unnecessary reporting requirements that takes us away from our frontline work and uncertainty about funding. It's time there was a widespread investigation into the DHHS and their culture and practices. FSV isn't an isolated instance.


Durability and quality are what customers look for when deciding on a pole set to proudly fly the flag year round. Our pole is 40% stronger than other poles in its class. Sizes noted are shown in feet above ground after installation.
* 16 gauge x 2" O.D. aluminum pole with satin anodized finish.
* Super strong halyard rope.
* 3/8" nylon snap hooks.


is to promote best practices in engaging and teaching boys through research, professional development, and programming. Since 2005, St. Christopher's teachers have participated in Action Research projects sponsored by the International Boys' Schools Coalition (IBSC). The Center for the Study of Boys is now excited to launch our own Saints Action Research team.
St. Christopher's faculty are undertaking Action Research projects to further the understanding of best practices for boys. The boys themselves play a vital role in the process by providing feedback on their experiences.
Saints Action Research team will explore the theme of Boys and Stories: Pathways to Learning during the 2018-19 school year. Check back soon for more information on this exciting initiative.
The 2017-18 Saints Action Research theme focused on Boys and Adaptability in a Changing World. Adaptable people possess a capacity to respond to uncertainty, change, and novelty, often with a positive attitude. They are further characterized by their creativity, resilience, and flexibility. In a competitive, high-achieving learning environment, our boys face many pressures, often dedicating time outside of school for extra tutors and coaches in an attempt to improve academic or athletic performance. There is little time left for the development of skills that foster adaptability. This year's research projects prompted teachers to incorporate concepts such as mindfulness and reflection, academic resilience, curiosity, and creative and flexible thinking into lessons in order to qualitatively measure how these skills affected adaptability in our boys. CLICK HERE to review the research briefs and hear from our teachers.
Action research is research driven by one teacher in his classroom investigating a component of his practice he wants to grow. The essential skill of collaboration is incorporated into all parts of of the curriculum; however, research indicates that boys often do not work particularly well in groups and may lack the necessary skills to do so. This study will test methods of teaching boys to recognize, respect, and maximize the different personalities and approaches to learning within a group in order to create engaging and innovative learning experiences. The goal is to find solidarity in Collaboration and the Power of Successful Learning Groups. CLICK HERE to review the research briefs and hear from our teachers.
CLICK HERE to review the research briefs and hear from our teachers.


text:
Movement of Professionals "Hope" (, MPSN) was a political party in Moldova led by Vladimir Florea.

History
Registered on 30 April 1997, the party joined the Social Democratic Bloc "Hope" alliance to contest the 1998 elections. However, the alliance received just 1.31% of the vote and failed to win a seat.

Prior to the 2001 elections the party joined the Braghiş Alliance. The Alliance won 19 seats, one of which was taken by the MPSN's Vitalis Mrug.

Following the 2003 local elections, in which the MPSN won just 21 seats and three mayoralties across the country, the party did not contest any further elections.

References

Defunct political parties in Moldova
Political parties established in 1997

redpajama_set_name: RedPajamaWikipedia


At St. John Catering, we want to make sure that your event reflects your style: from the setting to the main course to the bar offerings, and what better way to put your own twist on it than with a signature drink.
If you have a bar at your event, there are a few selections that most people like to include–mostly tropical drinks with a Virgin Islands staple: rum.
The most widely known is the Painkiller. It consists of both light and dark Cruzan rum, Coco Lopez (cream of coconut), orange juice and pineapple and is topped with freshly ground nutmeg. A great way to provide this for a party is to have the non-alcoholic version pre-mixed and to allow your bartender to pour the rum over ice and top it with the rest. This helps to ensure that guests are getting the right amount of alcohol for their own preference and to make sure that those who don't consume can still have a taste of this delicious blend.
Dark and Stormy's are also a favorite–traditionally done with Gosling's Black Seal Rum, topped with ginger beer, and garnished with a lime. These no fuss drinks are a great way to get the party going.
Last but not least is a classic Rum Punch. Let your guests choose either light or dark rum and serve it over ice with a blend of pineapple, orange and cranberry juice with a splash of grenadine.
These drinks, along with a full bar, make your event complete–but how about making it one to remember?
By including a signature drink in your menu, your guests will have a chance to try something new, and remember it always!
We have done the simplest of cocktails like Cruzan Cherry Rum and Coke to twists on the favorites like a 'Nilla Killa–a Painkiller with Cruzan Vanilla Rum to a special request that the bride called Stoli Doli–fresh pineapple infused Stoli on the rocks.
There are plenty of suggestions we have that were enjoyed in the past like a Coconut Mojito or a Passionfruit Margarita but the best part is that this cocktail embodies your special event.
Have something in mind? Just contact Mat to add your signature cocktail to the menu of your next event.
This entry was posted in Events, Recipes and tagged bar, catering, cherry coke, coconut, coconut mojito, cruzan rum, dark and stormy, friends, gathering, make it your own, margarita, Mathayom Private Chefs, mojito, orange, painkiller, Party tips, passionfruit, pineapple, private chef, recipe, rum, rum and coke, rum punch, signature drink, st. john, St. John Catering, Virgin Islands. Bookmark the permalink.


The flight there was 11 hours. We survived it. She fell asleep within the first couple hours and then was woken up by the baby crying in front of us after thirty minutes, and didn't sleep again until we landed. So...we survived. Toys, stickers, snacks, repeat.
The Narita airport is an hour from Tokyo station, so we decided to just stay in Tokyo for the night before heading out for further travel. We stayed in a tiny Airbnb where we all shared a futon (reminded me of her newborn days) and I began my endless thanksgiving that we decided to switch her to a bed on the floor before coming on this trip. We got famous Tayaki, fish shaped pancakes filled with sweet potato or sweet bean paste, in the evening and tried to stay up to a reasonable bedtime hour. In the morning Sloane was up at 4 am, and we managed to stay in until 6:30 am before leaving to get egg sandwiches from the convenience store and watch the sunrise across Ueno park.
While 4-5 am wakeups are not my preference, those sunrise walks we had in our first few days were some of my favourite times. The world was quiet, the air was crisp and the light fell cool and pastel across the waking streets. Elderly men out on their morning walk would smile and say ohayou gozaimasu (good morning), which wasn't to be expected any other time in Tokyo. We were refreshed and ready to explore.


text:
Dog of the Year photo contest terms and conditions
BBC Countryfile Magazine Dog of the Year 2020 terms and conditions
The Promoter is Immediate Media Company Bristol Limited.
The BBC Code of Conduct for competitions can be found at https://www.bbc.com/editorialguidelines/guidance/code-of-conduct and all BBC magazines comply with the Code.
The promotion is open to all residents of the UK, including the Channel Islands, aged 18 years or older, except the Promoter's employees or contractors and anyone connected with the promotion or their direct family members.
The closing date for entries is 23:59 on 31/08/2020
By entering the promotion, the participants agree:
– to be bound by these terms and conditions;
– that should they win the promotion, their name and likeness may be used by the Promoter for pre-arranged promotional purposes.
– that you keep the copyright but grant to BBC Countryfile Magazine and all of the magazines, websites and other businesses run by Immediate Media Company, a free and unlimited license to use, edit and reproduce your picture in our products and in marketing.
Entrants should enter by registering for a free account on AwardsForce, uploading their image and entering their details. Entries received after the closing date of the promotion will not be considered.
Entrants must supply to Immediate Media Company Limited their full name and daytime telephone number, dogs image and story. The Promoter will use entrants' personal details in accordance with the Immediate Privacy Policy (immediatemedia.co.uk/privacy-policy).
Only one entry will be permitted per person, regardless of method of entry. Bulk entries made by third parties will not be permitted.
Public voting for the BBC Countryfile Magazine Dog of the Year photo contest will open on at 00:01 on 01/09/2020 and close at 23:59 on 30/09/2020.
Members of the public can vote by registering for a free account on AwardsForce. They can vote for as many dogs as they wish but can only vote once per dog.
The 10 images with the highest number of public votes will be put before a panel of judges for them to select the (1) winner from.
The judges will base their decision on a series of criteria including image quality, composition and originality. The Promoter's decision as to the winner is final and no correspondence relating to the promotion will be entered into. The Promoter may share the winner's details with the prize provider for the purpose of fulfilling the prizes.
The prize for the (one) winner consists of 4x £250 vouchers for edgardcooper.com
The winners will be notified within 14 days of the close of the promotion by email. If the winner cannot be contacted or fails to respond within 28 days of such notification being sent, the Promoter reserves the right to offer the prize to a runner up, or to re-offer the prize in any future promotion.
The surname and county of residence of the winner will be available upon request by sending an SAE to Dog of the Year competition, Eagle House, Bristol, BS1 4ST within two months of the closing date of the promotion. The Promoter will contact the winners before releasing this information and provide the winners the opportunity to object or limit the amount of information shared.
There is no cash alternative and the prizes will not be transferable. Prizes must be taken as stated and cannot be deferred. The Promoter reserves the right to substitute the prizes with one of the same or greater value.
The Promoter reserves the right to amend these terms and conditions or to cancel, alter or amend the promotion at any stage, if deemed necessary in its opinion, or if circumstances arise outside of its control.
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redpajama_set_name: RedPajamaCommonCrawl


As you likely know, Congress is steeped in a debate to change US tax policy.
One of the most common financial mistakes individuals make is not utilizing available tax saving strategies. This results in you paying more taxes than necessary and missing out on years of future growth on the tax savings amount. As a result, we wanted to make sure you are aware of the potential impact new policies may have and consider taking action before the New Year.
Currently, both the House and Senate have passed versions of a tax bill and efforts to reconcile them are underway. The House and Senate aim to finish reconciling the two versions into one bill shortly, with the goal of having a final version on President Trump's desk by Christmas.
In the reconciliation process, negotiations will alter the final form of this proposed tax bill.
The #1 most important action step you can take TODAY is to contact your Certified Public Accountant (CPA) to determine if there are any planning strategies to implement before year-end. In particular, you should be evaluating if it is advisable to pull forward any currently deductible payments into 2017, including charitable contributions and items at risk of being eliminated or capped (such as property taxes, unreimbursed business expenses and state and local taxes).
Keep in mind, time-sensitive action items must be completed by December 31st.
One particular item to consider is that both the House and Senate's proposed tax plan would eliminate the deduction for state and local taxes. Property taxes would be limited to $10,000 in both plans so consider prepaying a portion before 12/31/17 to maximize the benefit. We highly recommend you review the potential impact of these proposals with your CPA.
Please reach out to your advisor if you would like to discuss further.


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The Governor Led a Muster on "West Java is Against The Act of Violence"
2016-07-18 13:32:00 | NEWS 488 VIEWS 0 COMMENTS | AUTHOR : REP-LIPUTAN
BANDUNG-The Governor of West Java, Ahmad Heryawan, directly led a muster in "West Java is Against The Act of Violence in Gedung Sate on Monday (18/7). The muster was started with pledge recital by students from throughout West Java.
In his speech the Governor said that he hopes there are no act of violence found in West Java. "There should be no act of violence such as an act of punishing phisically whether it is happening in school, within the family of inside the society," he hopes.
Furthermore, the Governor explained that "West Java used to be popular for its act of violence towards children and women, but today, West Java is becoming an exemplary region for handling act of violence in Indonesia. Especially since the establishment of P2TP2A," he said.
During the event, The Governor introduced a jargon which is "Kasih Sayang, Yes! Kekerasan, NO!" as he shouted it followed by all of the students.
Later on the event the Governor despatched a group of officials for an "Officials Go To School" programme.
In order to emphasize the commitment of the Government of West Java, The Governor wrote "Against the violence" on a banner followed by all of the students and the officials. Mrs. Netty and Mrs. Giselawati signed the banner and wrote their message.
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Lennox Town Center is a large multi-business retail property serving the affluent communities of Upper Arlington and Grandview Heights in the city of Columbus. In the middle of two active retailers was a parking lot which Summit Construction transformed into a 21,000 SF Marshalls in only 5 short months.
Summit Construction provided general contracting services for this project. In addition, Summit conducted several scope reviews with all the prequalified subcontractors going through the project details to get the best person for the job.
The benefit of this project is that it completes the large retail complex by conjoining all the tenants in a unified line. This adds value to the results because of the lack of any TJX companies in the nearby area.
In addition, this project has been successful in such an aggressive time frame finishing right on schedule and within budget. Part of the success of this project was scheduling the utility shut downs at nights to not disrupt any of the surrounding tenants.


Prevent injuries by choosing appropriate exercises and perfect organization of training. You will be able to consider surges respectively overtraining organism and correct interpretation of the current status of the organism. You will also learn how to conduct training in the reconditioning process, regeneration and rehabilitation using training with emphasis on the selection of special and general training means supporting an increase in total body fitness of an athlete.


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Clause 10 — Verification of information
Part of 18. Relief from Tax (Incidental and Consequential Charges) – in the House of Commons at 5:21 pm on 15th September 2010.
« Previous speaker
See the whole debate
Meg Hillier Shadow Minister (Home Office) 5:21 pm, 15th September 2010
Pete Wishart has done exactly as my right hon. Friend Mr Blunkett said and has begun to believe his own rhetoric, entertaining though it was to listen to. It might be helpful if I explain to him and to the rest of the House the position of the official Opposition. I remind the House that although many things are said in election campaigns, what happens in reality when people have power is often very different. We have a good example of that in front of us in the form of the coalition Government, but I shall say no more on that.
Her Majesty's Opposition recognise the Government's clear position and the reality of the maths. We know that both parties were elected on manifestos to get rid of ID cards and that the Bill is the fruition of what is a fairly rare point of agreement. Indeed, only on Monday the Under-Secretary of State for the Home Department, Lynne Featherstone, was speaking with enthusiasm about her position when she was in opposition and had to be quickly reminded of something by her Parliamentary Private Secretary, who passed her a note. She then swiftly began to read an alternative position from the coalition agreement, so we know that sometimes things are said but then change. However, the reality is that both parties agreed on this point and we recognise that that gives the Government a mandate. We are not here to oppose for the sake of opposition, but we feel that the Bill sweeps aside many important things.
On Second Reading, the Minister said that the Bill is symbolic-and it is for him and his Government. It is also ideologically based and very rushed. Had he been in his Department a bit longer and had other Ministers in that Department and in government thought things through, they might rue the day they swept away the baby with the bathwater. The Bill has the serious consequence of removing the option to have fingerprints in passports, which the identity register allowed. That would have updated the passport database to allow for the very secure retention of that important biometric.
The hon. Member for Perth and North Perthshire is very exercised about data being held by the state. I am sure that he must have a passport for travel and I wonder whether he has ever given a moment's thought to where passport information is held. As I reminded members of the public and others up and down the country during many of my roadshows, visits and talks about this issue over three years, 80% of us have a passport and that information is held securely. We have a good Passport Service, but what we proposed was a more secure approach. I shall not dwell on what we could have done or what we would do differently again, but it is an important principle of the Opposition that the passport should be secure not only now but in future. The new design for a more secure physical passport that I signed off earlier in the year has been unveiled and produced in the Blaydon constituency. We wanted greater security with fingerprinting, but the Government have effectively abandoned that.
Interestingly, the Bill sets the tone for the way in which the Government wish to work. It was brought forward in quite a rush. We finally managed today to extract from the Government the fact that there was no consultation on the Bill, so mentions in manifestos and on individuals' blogs seem to be the way in which the Government choose to consult. We also know that the Bill's impact assessment was inadequate, which is sad, given that one of the Ministers responsible for the Bill is also the Minister for Equalities. Labour Members will watch closely to ensure that such sloppiness does not take place in the future, and I hope that Ministers acknowledge that they have a responsibility to do their jobs thoroughly and properly.
We look forward to hearing more about the transgender issue raised by my hon. Friend Julie Hilling. We tried to put in place something that would make the best of a bad job in this regard, but the Government removed that option overnight without any recognition of that fact. No full solution is forthcoming, so we ask the Government to report to Parliament as progress is made on the issue. I ask the Minister with responsibility for passports to write to me around Christmas or in January to let me know what progress has been made, and to place a copy of the letter in the Library. I have been contacted by many people who would be grateful for such information. A lot of them do not have voices of their own, but they will be looking closely at how the House scrutinises the issue and have made it clear that they want to know what is going on.
The Bill prevents the Government from collecting and storing fingerprints, which means that the British passport will fall behind international standards relatively quickly, although international passports improve over years. Over time, British citizens will be forced to pay for visas when they make certain international visits. The Prime Minister and the Foreign Secretary have indicated that they favour biometrics on passports and increasing passport security, so I wonder whether the Bill has been fully squared in government. We hear that the Government are halting the use of fingerprints, but we do not know for how long. I hope that they will consider putting that back on the table because we all have a genuine interest in ensuring that the British public are safe when they travel and that our identity documents are as secure as possible. The use of fingerprints also helps to tackle identity fraud because many criminals have multiple identities, yet fingerprints are one of the surest ways of prevention.
I know that Ministers take seriously the Home Office's responsibility to do everything in its power to protect people-that is the Department's raison d'être-but the Bill throws out the baby with the bathwater. The Opposition would revisit the issue of biometrics on passports, even though I give no commitment about what we would do on identity cards, given that we will shortly be under new leadership. However, if we were to get into power in five years' time, we would be in a different place than if we were not to get into power-heaven forefend-for 10 years. We recognise that we will have to deal with the landscape that we face at the time. I would hope that that landscape would involve fingerprints for passports, but the Bill does not make that look likely.
The Bill's refusal of any recompense to those who bought cards in good faith is mean-spirited, as is the fact that we have had no opportunity to press for refunds, which was the reason why some of the new clauses that we tabled were complex. As I said, no proper account was taken of the equalities impact. If I was to be particularly mean, I would suggest that the mean-spirited nature of the Bill is a metaphor for the Government as we approach tough spending decisions.
I thank hon. Members who have played an important part in developing our policy and supporting my Front-Bench role. The Opposition's redoubtable team has mostly consisted of newly elected Back Benchers, who have been committed to addressing the Bill. I put on record my thanks to the former right hon. Members for Redditch, for Norwich South and for Airdrie and Shotts, the last of whom will no doubt give the Bill a run for its money in the other place, as well as my right hon. Friend the Member for Sheffield, Brightside and Hillsborough. It is rare that a junior Front-Bench spokesman has such support from a series of former Home Secretaries, but they have been incredibly supportive and helpful.
We are not yet dancing on the grave of identity cards. I live in hope that the Government will see the error of their ways and that, despite this Bill, they will revisit the issue of passport biometrics. I look forward to seeing how the Bill progresses in the Lords.
Question put and agreed to .
Bill accordingly read the Third time and passed.
See this speech in context
Hansard source (Citation: HC Deb, 15 September 2010, c967)


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Image tools for social media sharing

redpajama_set_name: RedPajamaGithub


Companies must know what topics are being discussed on social media - especially during high profile crisis. They also need to monitor their own brand mentions for a potential crisis that could arise. Implementing an issues management program through social media can save a lot of headaches and stop issues before they become their own crisis.
Issues management is the proactive process of anticipating, identifying, evaluating and responding to issues that organizations face. Social media – especially Twitter – is often an early warning tool for potential brand issues that could arise.
Monitor for brand mentions. Monitoring for mentions of the company on social media will help you know what is being said about you and your solutions. If an update to a software offering you have doesn't work, chances are that someone will post about it on Twitter or in a forum or community. Knowing about it early will allow you to prepare to best respond, and get working on solving the issue before it affects a wider amount of people.
Monitor for competitive mentions. Seeing what competitors are doing will give insight into how they position against you. More than once in my career a competitor to one of my clients made a claim that isn't true. Knowing early allows you to go on the offensive to clear up misperceptions and call them on the carpet for false claims. You'll also be able to see and learn about their positioning and how they deal with issues they face.
Monitor for industry events, national and global issues. By knowing what is going on in the broader world, you can modify your programs or scheduled activities appropriately. You don't want to damage your brand by saying something insensitive during a time of broader crisis like the NRA did in the hours after the Newton school shootings.
Having a process in place to address these issues as they arise is crucial to making sure you are able to respond appropriately. By following these steps you can ensure your organization is poised to quickly respond to an escalated social media situation through effective communications and appropriate action.
What do you do to keep an issue from becoming a crisis? Leave a comment below.


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PSC Discusses Critical Staffing Needs with State Superintendent Thurmond
Last week the Pupil Service Coalition (PSC) met with State Superintendent Tony Thurmond to detail California's 40-year practice of understaffing pupil service personnel working in California schools.
Representatives from school counselors, school nursing, school psychology, school social work and California Teachers Association were present. Committee representatives raised concerns with Thurmond regarding the distressingly high ratios for pupil services staff in California. They indicated that California maintains some of the highest student to pupil service staff in the country. They also discussed the lack of staff at the California Department of Education dedicated solely to overseeing each profession. Thurmond committed his support to strengthening the numbers and asked for the PPS help in doing so. He also pledged to support the PSC committee's work by assigning a staff member from his office to attend the meetings and report committee work directly to him. This is a significant move, allowing the PSC to have a direct line of communication with the Superintendent.
The PSC was formed approximately 20 year ago. Representative from each organization meet monthly on behalf of the over 20,000 pupil service staff working in California schools (school counselors, school psychologist, school nurses and school social workers). Representing CASC are Marilyn Harryman from El Cerrito and Dr. Loretta Whitson, CASC Executive Director. Patty Taylor, CASC Assistant Executive Director is also a key member and is in attendance on behalf of the California Teachers Association. This committee demonstrates just one of the strategic activism efforts CASC participates in regularly. We are grateful that the PSC has been at the helm of advocating for issues important to the school counseling profession over the years.


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