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"Santa Catalina--Our Island Staycation was a big success "
.. By Joe Hilbers
It did not take us long to adopt the Catalina slogan, "Relax, You're on Island Time." In fact we were not on the Island even 24 hours before becoming a quick learner. Sitting on our personal deck at the Catalina Beach House overlooking the harbor and tranquil sea we remembered we had not shaved, then after some deliberation said, "why bother." This and where to have lunch were our big decisions for the day.
True we had planned this trip to Catalina, our first in a quarter century, to gather stories for Vittles. But then they began to appear almost without effort on our part.
Example One. We had dinner one evening at the Catalina Country Club. This club house and golf course was built by William Wrigley as a place of entertainment and relaxation for his Chicago Cub ball players who did their spring training on the Island each year. Here we heard an interesting story. Our dinner at the club will be the subject of a review in the next issue of Vittles.
In 1936 and again in 1937 a young sports announcer from Des Moines arranged to join the Chicago team for its spring training on the Island.
His name was Dutch Reagan and being personable, enthusiastic and with a gift for interesting conversation he soon became accepted and liked by the Cub management, coaches and players. In fact now and then he would suit up with the team for batting practice. The players knew he had what they called a 'slow bat' but it was all in good fun and the pitchers never threw him their 'good stuff'.
Also Dutch truly enjoyed Mr. Wrigley's stables where he could get a horse to ride the challenging trails and wild back country of the island.
Then in 1937 while still in California Dutch Reagan took a screen test in Hollywood which was most successful and so signed to a contract. The name Dutch was dropped and from then on it was Ronald Reagan. The rest as the saying goes 'is history'.
Example Two. Our stay at Avalon was at Catalina Beach House. We considered this a grand choice for the low key approach we brought to this assignment. On arrival we were handed a key by a pretty young lady who said 'enjoy". Our room, which included a spacious porch and deck, offered an entrancing view of the harbor while surrounded by the diverse architecture of the neighboring buildings some perched on steep slopes, seemingly defying gravity. It also had a large screen lcd-hdtv (which we ignored, no political ads this trip) as well as a complete mini kitchen with stove, refrigerator, dinnerware and utensils. Like the TV this we also ignored, no cooking for us this trip. However we definitely did not ignore the whirlpool tub.
But the Beach House is a fascinating story about yet another enterprising man of an earlier generation. It was in 1912 that Captain Joseph McAfee sailed his flat bottom houseboat from Venice Beach to Santa Catalina Island with the intention of making Avalon his home. He purchased a hillside lot on what is now Marilla avenue and then hauled his house boat out of the water and up the hill to rest on his newly purchased property. Reportedly using horses, logs and the help of friends he inched the boat up that steep slope to its resting place where it still sits today. As we lounged on our deck we wondered how he ever managed it. Perhaps in an earlier life he had helped built the pyramids.
It then became 'the Captain's Beach House' and over time the Captain added rooms for the tourist trade. He also is the man who built the first boat to show the Island's famous flying fish. Through the years the name changed a few times but recently the Catalina Beach House has enjoyed still another renovation as well as new owners. We chatted with Mindy Malan who now manages the hotel for her father, new owner Mark Malan. We complimented Mindy on the bright pleasant colors of our room and learned it was only completed with its new furnishings and decor one month earlier. The Catalina Beach House is located at 200 Marilla Avenue, steps away from everything at Avalon. For information and reservations call 310 510-1078.
Example Three. The Tuna Club has played a huge role in establishing Catalina as a paradise for the sport of game fishing. The most successful western novelist Zane Gray was one who came to the Island for the fishing, liked it so well, that he built a home at Avalon that still stands
The Tuna Club even enjoyed a role in the classic movie "Chinatown".
One prominent guest to the Tuna Club was Winston Churchill who was a visitor in 1929. Being Winston he wanted to find out for himself just what this marlin fishing was all about. He was only in the fishing boat 20 minutes when he hooked a 188 pound Marlin. And shortly after had it in the boat
Afterward he was heard to comment that he couldn't see what all the fuss was about with this fishing thing. Presumably he considered overwhelming his political opponents with his brilliant oratory in the House of Commons a much more interesting sport.
Example Four. Since our own dabbling in oil painting we have an increased interest in art galleries. In wandering the streets of Avalon we looked in on the Ruth Mayer Gallery. Here were exhibited an incredibly versatile collection of oil paintings, all by one talented woman. Ruth Mayer has had a Catalina studio for 60 years and her son, Reed, operates the Gallery. Most interesting is that in 2004 she was commissioned to paint a portrait of Pope John ll and this was completed and shown to the Pope at a private Vatican viewing. Reproductions of this painting are on view at the Gallery located at 116 Sumner Avenue. Also many examples of her work can be seen on her website www.ruthmayer.com.
If you have to travel on water, admittedly not our thing, the Catalina Express is about the best we have experienced in a long time. We departed from the Long Beach Express terminal conveniently located next to adequate parking. The Terminal is roomy, comfortable and the staff friendly. Once aboard the good ship Jet Cat Express we settled in at the Commodore Lounge. We recommend upgrading to the Commodore Lounge with amenities something like first class on a jet plane.
Snacks and a cocktail are complementary in the Commodore Lounge which also places one higher on the ship. On a calm sea with time to watch pods of dolphins we arrived promptly at Avalon exactly one hour after our Long Beach departure. The ships of Catalina Express also depart from San Pedro and Dana Point. For reservations and information call 310 519-1212 or 800 618-5533, on the web at CatalinaExpress.com.
In the next issue of Vittles we will report on what we learned on our Discovery Tours, our explorations at the Casino and the Catalina Museum as well as our dining experience at the Catalina Country Club.
Avalon is now a regular port of call for cruise ships and two arrived on consecutive days during our stay on the Island. One was the Paradise and the second Monarch of the Sea. We thought we could always identify the folks on shore leave from the ships. They were intense and anxious to get things done.
Not a bit like us locals who after all were "On Island Time".


If you impress your audience with great imagery, your are making a great first impression. Great first impressions draw the consumer in, often leading them to narrowing down their options quicker, and eventually lead to decision making and closed sales. When selling architecture or real estate, the first photo a potential buyer sees of a penthouse condo, luxury home or apartment, should be a strong representation of the community and the home. Less-than-flattering pictures can turn buyers off and lead to lonely open houses.
We enjoy our loyal clients who come back to us for repeat interior and exterior photography projects. One client mentioned after implementing their first home's photos, a new home buyer and customer mentioned "upon first seeing this amazing photo, I knew I wanted to live in life in that photo and enjoy that lifestyle." Through the use of photography and building a company's corporate image or company brand with photographs, developers, builders, marketing experts and more commonly say establishing a brand can create an impact on your audience.
As Chicago architectural photographers, we are capable of not only interior and exterior home photography such as the photographs previewed above, but we offer the option to provide photos beyond the single property or typical home photos. Often we are commissioned to not only capture indoor and outdoor home photos of our client's personal residence or the agent's listed home, whether being a residential location such as a rooftop penthouse, loft, condominium, or luxury townhome or photos of a commercial property, photography of a new condo construction project in Chicago, multi unit suburban or downtown development, or investment property, but we are happy to also provide and offer an option to upgrade our services with extra architectural photography items such as aerial photography, environment architecture photographs, lifestyle photography, nearby location landmarks, travel and leisure photography.
For this project, we photographed a two bedroom, two bath luxury condo located in Chicago's South Loop neighborhood in a high-rise tower within the One Museum Park West Tower IV development. With it's ideal and prime development location on Lake Michigan, this waterfront location overlooks Chicago's Grant Park, The Field Museum, Adler Planetarium, Solider Field Stadium, boats, yachts and Chicago Burnham Harbor. We talked about how the One Museum Park West development offers homebuyers not only to buy an amazing property, but they are also buying a lifestyle and the nearby urban community which goes along with living in the South Loop neighborhood. Our client decided to add on a day of Chicago architecture photographs which was beyond the real estate interior and exterior photography. Our architecture focus was to capture lifestyle photos all within viewing distance of the penthouse condo's balcony. Locations included a few City landmarks viewed from the terrace such as Buckingham Fountain, pictures of the museums, Chicago yacht club, aerial photos of Soldier Field, and a full exterior skyscraper building photographs from Grant Park showcasing the properties proximity to the nearby Loop and business corridor. This South Loop development is ideally located close for commuters into the Loop, with easy travel to downtown commercial and corporate buildings. Within the Park West Tower IV building, we captured photos of the high-rise building's pool and resident amenities. The extra photographs beyond the real estate and luxury condo photography home tour pictures were a perfect compliment to help illustrate and sell a lifestyle photographically.
So whether your marketing a metropolitan landmark, looking to feature a destination or travel location through photography, or selling a property, while searching online real estate agents, sales and marketing departments, online listing services, and web designers all agree, great imagery provides to the seller or end user a great impression. We look forward to your contact and please send us an email so we can learn more about your travel photography project, your future development either underway in construction or completed, or your luxury home or residence's marketing photography needs. We travel often, so our capabilities are not limited to the Northern Illinois metropolitan area. We are available to travel to a number of destinations in urban regions, cities and towns around the U.S., and occasionally outside of the Nation for International projects.
Donald Trump's Trump International Hotel & Tower Chicago changed the landscape of Chicago's skyline. Currently one of the City's newest skyscraper condo-hotels, it is located in Chicago's River North Gallery District. The multi-use commercial, hospitality and residential landmark rises 92 stories high. Located just steps from the Magnificent Mile and ideally located the North side of the Chicago River with clear Eastern views of Lake Michigan. It's urban location is West of the Wrigley Building and just East of the iconic Marina City. Hat's off to Bill Rancic of Donald Trump's hit TV show's The Apprentice for managing the construction of this iconic Chicago River building. It has to be rewarding for Bill & wife Giuliana DePandi (Former E! entertainment News anchor co-host) to see such an iconic building in the heart of Chicago that he helped develop.
Miller + Miller Architectural Photography is an interior and exterior architectural photographer team of Ryan and Sarah Miller who's limits are endless … skyscraper architectural photos, luxury high-rise condominium photography, 5-star hotel interior photography, boutique hotel, resorts, business plazas, architectural landmarks, lavish estates, commercial properties, industrial skyscrapers or residential high-rise Chicago buildings.
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Dynasty Trade Value Chart: July
Long-Term Player Values for Dynasty Leagues
by Dan Hindery, July 2
July is our final opportunity to buy low on some undervalued veterans before the reality of trying to win fantasy matchups in the fall really sets in for everyone in August. The dynasty calendar has predictable ebbs and flows in player value. In the offseason, most dynasty owners get caught up in trying to build a pretty roster. In this context, "pretty" means a roster loaded with youth. A team that — at least on paper and with some optimistic assumptions built in — can be dominant over the long haul. That mindset starts to shift in August when we see depth charts solidify and the focus turns to actually trying to win. Some of the hype starts to wear off and veteran players poised to produce big numbers see their value rebound. Highlighting some of these remaining buy-low opportunities that are likely to disappear when training camps open will be a focus of this month's Dynasty Trade Value Chart.
It may also be our last, best opportunity to cash in on some of the hype and optimism surrounding younger players who aren't guaranteed to make an impact and who could see their trade value slide over the next few months. For example, we know that a decent percentage of the wide receivers in this rookie class isn't going to make an impact. We should be willing to cut bait early if the opportunity arises to sell high and we feel there are some signs that our rookie or young veteran might be overvalued. We will also note some of these players this month.
The dynasty trade value chart is tailored to 12-team PPR leagues a starting lineup of one quarterback, two running backs, three wide receivers, one tight end, and one flex. It now also includes values for Superflex leagues. The chart is meant to serve primarily as a guide for trades but can also be a great resource during startup drafts. If the players and picks on each side of the trade offer add up to approximately the same number, the trade would be considered even. If you receive a trade offer that sends you players with a higher total number value than the players you are giving up, the offer is worth strongly considering. Each league is different, so pay close attention to the scoring and starting roster requirements specific to your league.

redpajama_set_name: RedPajamaCommonCrawl


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Q: Doubt about semigroups in this article (anyone can help). I need help in this article. My doubt is very arithmetical and I think follows directly from the definitions. So I think anyone could help me.
The author defines what is a semigroup, gaps and non-gaps:

After that he defines what is a symmetric semigroup:

So that's my doubt:

However what I found directly from above was:
Since $H$ is not symmetric we have $\#(nL)\le nl_g-n+1\lt n(2g-1)-n+1$ which is different from the inequality the author found: $\#(nL)\lt (2n-1)(g-1)$.
I'm sure I'm forgetting some silly thing.
I need help.
Thanks.

redpajama_set_name: RedPajamaStackExchange


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Q: How to adjust container in bootstrap 3? How can I ajdust container to make it full width?
This is the space that's container taking right now, but I want it to have full width (like website).
I have created it like this

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I have tried adjusting css like:
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width: 100%;
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but it doesn't work... Help please!


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Home › News › Kelsey Shoemaker
Kelsey Shoemaker
Senior Kelsey Shoemaker from Ashland wasn't always interested in agriculture, so her choice of Agricultural Business with a concentration in Plant Science is a bit of a surprise.
"As I reflect on the journey that led me to the agribusiness program at Louisiana Tech, I can't help but chuckle at the irony of it all," Shoemaker said. "Going into high school, I didn't have an agricultural background, and truthfully, I was completely disinterested in acquiring one. If it hadn't been for the persistent recruiting attempts of a dear friend, I never would have found my passion for plant science through Future Farmers of America (FFA). In my junior and senior year of high school, I was incredibly blessed to be a part of my FFA chapter's Nursery/Landscape team. It was that experience that opened my eyes to the fascinating intricacies of plants for the first time, and I quickly became immersed in a new world that begged to be explored. I knew that Louisiana Tech's unique Agribusiness/Plant Science program would enable me to build a platform for various career opportunities while continuing to pursue what I love."
FFA brought Shoemaker a dedicated mentor in the form of advisor Ryan Riley, who encouraged her to explore her interests in plant science.
"At Louisiana Tech, God has blessed me with yet another amazing advisor and mentor, Dr. Paul Jackson," Shoemaker said. "I've come to find that he believes in me more strongly than I believe in myself, and he demonstrates that by challenging me to embrace new opportunities. Having his support truly inspires me to pursue horizons that I never dreamed were achievable, as I hope to explore graduate school opportunities this year.
"I am so grateful for him and all of the investments he is making in my life to prepare me for what lies ahead. Despite the uncertainty of what my future holds, I couldn't be more confident in my desire to make a difference in the lives of others in the same way that my mentors have for me."


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' ); var proStockMotorcycleCnt = 10; var proStockCnt = 10; var funnyCarCnt = 10; var topFuelCarCnt = 10; switch(tab) { case "pro-stock-motorcycle": setClinchedStyle(proStockMotorcycleCnt, bgColor ); break; case "pro-stock": setClinchedStyle(proStockCnt , bgColor ); break; case "funny-car": setClinchedStyle(funnyCarCnt , bgColor ); break; case "top-fuel-car": default: setClinchedStyle(topFuelCarCnt , bgColor ); break; } } } //SetWinnerName() function, workaroiund to set missing nam ein results function setWinnerName() { var uri = window.location.pathname; var testBaseUri = "/results/2017/nhra-mello-yello-drag-racing-series/1311"; var testWithCategory = testBaseUri + "/detailed-results/super-street"; if ( testWithCategory == uri) { var str = 'Chris Borges WIN'; jQuery(".table__row-winner .table__left").html(str); } testWithCategory = testBaseUri + "/winners"; if( testBaseUri == uri || testWithCategory == uri ) { jQuery( "td:contains('Super Street')" ).prev().html( "Chris Borges"); } } //SetTimingMessage() function function SetTimingMessage() { var uri = window.location.pathname; var testBaseUri = "/results/2017/nhra-mello-yello-drag-racing-series/7076"; var testWithCategory = testBaseUri + "/live-timing"; var str = '
Live Timing is experiencing connectivity difficulties. It will be back to normal within the hour.
'; if ( testBaseUri == uri || testWithCategory == uri ) { jQuery(".section-header__content").append(str); } } window.addEventListener("load", function() { setTimeout(function(){ setClinched(); }, 1000); setTimeout(function(){ setWinnerName(); }, 350); setTimeout(function(){ SetTimingMessage(); }, 1000); }); //End Temporary Clinch Logic
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89 questions about Chris "the Greek" Karamesines (or should there be 92?)
50 years, 10 manufacturers, 84 body styles: A guide to Pro Stock diversity
Yuichi Oyama. Who? Japanese Top Fuel racer made waves, scored upsets in 2002
Name a random NHRA racer ... go
1971: Garlits goes 'Big,' Funnies go 220, Sox goes wild, and NHRA goes to Canada
Welcome back, and welcome to my great drag racing debates
Exclusive book excerpt: Don "the Snake" Prudhomme: My Life Beyond the 1320
Swamp Rat 14 rides again; the history of one of Top Fuel's most important cars
Everything you always wanted to know about 'Snake' (but were afraid to ask)
Dave Miller: Diamond in the rough
Quiz: Drag racing's hometown heroes
Reliving the U.S. Nationals Top Fuel final that no one will ever forget
Tony Schumacher: Indy Top Fuel dominator
Remembering Fuel Altered pioneer Leon Fitzgerald, Pro Stock's Sonny Bryant
Remembering Zim
The history of the Summernationals
The Kuhl one
Fan Fotos: A Texas-sized collection from three decades of photo greatness
Down the video rabbit hole: Watching 1970s match racing on the small screen
Roll players: A look back at the era when cars were fired up with roller starters
The day that Mario Andretti went drag racing in a Tasca Ford-prepped Mustang
Farewell to a fearsome fuel foursome
Farewell to a brother editor, Jim Edmunds
Remembering Barbara Hamilton
Remembering Jack Ditmars
Fan Fotos: Top Fuelers, Funny Cars, and Pro Stockers of the early 1980s, Part 2
Fan Fotos: Top Fuelers, Funny Cars, and Pro Stockers of the early 1980s
History class is in session: More than 700 articles covering the legends of drag racing
Barry Setzer, Pat Foster, and their amazing Vega
Phil Burgess, National Dragster Editor
The Top 20 Funny Cars list rolls on, headed soon for the top 10, and although there were no assurances of anyone's position -- due in no small part to the strength of "the field," each having earned a berth based on the sheer weight of evidence for inclusion – it's fair to say that the last few unveilings have ruined many a "perfect bracket" some of you may have been harboring.
For me, one of the "ouch" moments was when the fabled Pat Foster-driven Barry Setzer Vega was announced in the No. 13 spot. Blame it on the rather nondescript name of the car or its short-lived (two seasons) history, but it was in my personal top 10. As a young fan devouring racing magazines and turning up at SoCal dragstrips as often as I could beg and bargain my parents for a ride in the early 1970s, the Ed Pink-powered Vega seemed nearly indestructible. "Patty Faster" might not always win the race, but he and Setzer almost always left with low e.t., top speed, or both.
For decades, Setzer has been a bit of an enigma for me. I can't find a single magazine interview that he ever did, and all that most of us know is that he owned a pretty successful textile business in North Carolina and that for a few years he bankrolled a racing team. I've written about him several times but always from a third-person, historical perspective.
So, before it's too late – you know what I mean – I thought it was time to try to unravel the mystery. He wasn't easy to track down, but eventually, Cole Foster – Pat's son – was able to get me a cellphone number. Setzer, now in his early 70s, was clearly surprised by my out-of-the-blue call and admitted right away that he had never been one for the limelight.
"The spotlight has always been the place where I've been least comfortable, and I always thought I should let the car speak for itself," he explained of the absence of any previous interviews. "The owner of the great horse Secretariat always said the best spokesman for Secretariat was Secretariat."
His modesty notwithstanding, Setzer spent an engaging half-hour with me and had very fond and wonderfully clear memories of his brief but highlight-filled time in the sport.
Dispelling any notion that he was just the wallet behind the magnificent machine, Setzer grew up in sport and can vividly remember as a teenager watching Don Garlits race on the old abandoned Air Force strip in Chester, S.C., before turning his trackside viewing into on-track doing, racing a '55 Chevy and then a big-block Chevy II Super Stocker. He teamed with driver Bruce Walker on a "match race Super Stock" Camaro that became a Pro Stocker, which is how he met Ed Pink. Pink built an all-aluminum engine for the Camaro, which led to introductions to Funny Car drivers and chassis builder John Buttera.
"I decided that I'd like to have a Funny Car, so I had Buttera build me one, and we ran it out of Ed's shop," he recalled. "I was just an old country boy who had been in awe of all of the California guys, but once I got to meet them and spend some time with them, I figured out, 'Why, hell … they're just guys, too.' We started sharing thoughts and ideas, and I really enjoyed that part of it."
The 28-year-old entrepreneur hired the highly regarded Kelly Brown as his driver, and together they scored a runner-up at the 1971 NHRA Springnationals in Dallas (right). At the time, Foster was driving Don Cook's Damn Yankee Barracuda, which also had a Pink powerplant, and, as Foster told me in 2008, on a fraction of the budget, it consistently outperformed Setzer's car, which was the Pink "house car," so to speak.
"That caught Pink's attention," Foster told me. "He asked me to help him with the Setzer car at a test session at Orange County Int'l Raceway. My answer to Ed was, 'No deal. Put me in the car on a permanent basis, and we'll talk.' He did that, and from then till Barry quit drag racing in 1973, we did well."
"I needed someone in the seat that had a little more clutch experience, and I think Pat was way ahead of his time in that area," Setzer explained. "He understood how it worked better than anyone. As soon as we put him in the car, it started going quicker and faster. Also at that time, Ed was experimenting with bigger fuel pumps and more magneto voltage, and the notion of experimenting and being creative is also how I became successful in the textile business, so I was all for it. I always was interested in doing something a little different than how everyone else was doing it."
Setzer was an innovative businessman who funded his racing efforts with a number of successful textile businesses, including Barr Craft Knitting, Barr Hosiery, and Barr Textile Dyeing.
Setzer's textile business at the time – he'd sell and buy back the company several times in different iterations over 20-plus years – was Barr Craft Knitting, which specialized in covered elastic yarn and narrow elastic fabric, the kind that goes into underwear waistbands, bra straps, and lingerie.
"Back in that day, there was a product for the ladies called support pantyhose, and we were the biggest supplier of elastic to Hanes and L'eggs," he said modestly. "We did all right for ourselves."
(Although Setzer is no longer involved with his original company, fabric continues to weave its way into his life. He now owns Victory 8 Gardens, which sells EZ-Gro Gardens, portable raised-bed gardens that use a proprietary, nonwoven propylene fabric called AeroFlow.)
Foster took over the wheel of the candy-red and gold Vega after Indy in 1971 and immediately drove the car to a win at the prestigious Manufacturers Meet at Orange County. How big was the Manufacturers Meet back then? Nearly 70 Funny Cars were on hand, and it took nine hours to complete qualifying to set the four eight-car fields for the Dodge, Plymouth, Ford, and General Motors teams. The Plymouth team, led by Don Prudhomme and Jim Dunn, won the team title, but Foster won the overall driver's championship — a final run between the cars with the night's two low e.t.s — when he beat Dunn, 6.72 to 6.77.
(Picturfed right) Don Schumacher (note 356 car number) got a guest shot in the Setzer Vega at Lions Drag Strip in September 1971. He lost the then-quickest Funny Car race of all time, 6.55 to 6.60 to Gene Snow. (Jere Alhadeff photo)
The promise shown in late 1971 revealed itself in full fury in 1972, especially during a five-week stretch in midsummer when they scored a home-state triumph for Setzer at the IHRA Pro-Am in Rockingham, N.C. (where they also set the IHRA national speed record), then won OCIR's Big Four Manufacturers Championship (with a track record 6.52), triumphed at a smaller weekly show at Irwindale Raceway, and dominated the Hang Ten 500 at OCIR.
As testament to the team, between the Irwindale win and the last OCIR victory, they went to Lions Drag Strip and blew the body to smithereens (Foster even crunched the guardrail), but a week later, they killed 'em at OCIR, qualifying No. 1 and running low e.t. of all four rounds — including a track record 6.47 — and again beating Dunn in the final. They finished the season on a high note at the NHRA Supernationals at Ontario Motor Speedway, carding the sport's first 6.2-second Funny Car run, a 6.29, in round one. Foster added passes of 6.30 and 6.31 before red-lighting in the final to (who else?) Dunn, who scored his historic first (and only) win with his rear-engine 'Cuda.
The duo closed their first full season together by setting low e.t. and top speed of the meet at Lions' Last Drag Race with a 6.36, 229.59-mph effort late in qualifying but were unable to return for eliminations because the chutes ripped off the car on the pass, which sent Foster into the sand trap, damaging the car.
"We went after it seriously on every run, like every run was for the national championship," said Foster years ago. "We got chided by some of the smaller teams for running that way, but I told them I had a car owner who wanted to tip the world over every time we went to the starting line and that was my job."
"Of course I always wanted to win," Setzer confirmed, "but I always loved seeing the car go quick and fast, too."
The Setzer Vega kicked off 1973 by winning the All-Pro race at OCIR, beating Sush Matsubara in the final (Foster also set top speed at 223.32 mph), and followed with a convincing win at the IHRA Winternationals at Florida's Lakeland Dragway, where he ran low e.t. in the final to beat Ron O'Donnell. The team then collected its first NHRA score at the Gatornationals, where it set a new national record of 6.36, backed up by a 6.37 in the final round to defeat Don Schumacher. The Setzer machine went on to record two more NHRA runner-up finishes, at that year's Springnationals and Summernationals, to Dave Beebe and Leroy Goldstein, respectively. At the Summernationals, Foster qualified third on a fiery 6.47 pass that left him with burns. He bravely soldiered on and reached the final, where he fell to Goldstein and the Candies & Hughes machine, 6.74 to 6.78.
"We did better in match race and IHRA competition," admitted Foster. "The car was good enough to win even more NHRA events, but something always seemed to happen to us in the final."
Foster qualified No. 1 at the IHRA Pro-Am at Rockingham Dragway and was runner-up to Mike Snively in the Mr. Ed Satellite and set low e.t. at the IHRA Springnationals in Bristol. Foster set top speed at the IHRA Northern Nationals and lost in the final to Jim Paoli. Later that year, Foster and Setzer won the IHRA U.S. Open, stopping Dale Emery in the final.
Foster and Setzer parted company at the end of the 1973 season. Setzer had met "a charming young lady" and got married, but before you start thinking it's "Yoko broke up the Beatles," Setzer is clear that the decision to quit was his.
"It wasn't that she didn't want me to go drag racing," he explained. "I realized that I couldn't be the world's greatest husband, operate a successful business, and be the owner of the world's fastest Funny Car. The time was right, and I decided to move on. Everyone's interests follow different courses over time. Some people live their lives doing what they started out doing. I respect and admire those people, but I'm not that way. The creating and the building was always more exciting than the actual doing."
(Pictured right) Tommy Grove drove a Setzer-branded Vega for a number of seasons after Setzer retired from being an active car owner.
Setzer offered to sell the complete operation to Foster, who declined and later very much regretted it. "I didn't want the headaches of being an owner," Foster admitted. "Don Prudhomme later told me that I had been a fool, and he was right. I had everything that I needed to turn the program into a major sponsorship deal."
The Setzer name remained visible on a Setzer-branded Vega driven for several seasons by Tommy Grove. Setzer had no real involvement in the car – the arrangement began when Grove garaged his car at Setzer's shop – but he did work more closely with Lamar Walden on a locally run Pro Stock Vega that carried Setzer's name in the 1974 and 1975 seasons, a car that Setzer believes could have been a great car if they ever had the chance to sort it out.
Even while he owned the Funny Car, Setzer had his hands in both other Pro classes as well. After Bill Jenkins showed the way in Pro Stock with his small-block Vega, Setzer had Buttera build him another cutting-edge vehicle.
Recalled Buttera in a 2001 interview with NHRA National Dragster, "One of the problems that they had with the [Pro Stock] Camaro was that it was so difficult to work on. Barry wanted to make the car more accessible, and I said, 'If that's what you want, watch this.' "
The result, according to former NHRA National Dragster writer and Pro Stock historian John Jodauga, was the first "take-apart" Pro Stock car, on which each body panel, with the exception of the roof and rear quarterpanels, could be easily removed with a variety of quick-disconnect devices. The vehicle earned Best Engineered Car honors at the season-opening 1973 Winternationals. "Although it did not knock Jenkins off of the top of the Pro Stock totem pole, its engineering innovations are still very present in today's machines," wrote Jodauga in a 2001 ND article.
Setzer's trust in Buttera was so supreme that he even bought Buttera's wild, monocoque-chassised Top Fueler – an extraordinary machine combining aircraft, aerospace, Indy 500, Can-Am, and Formula 1 technology that I wrote about in a 2010 column that I titled "The prettiest car to ever run only once," which goes a long way in summing up the wild ride – after Buttera could not find the financing himself to field the car after a six-month build. The car, as my title implies, only ran once (that we know of), wheelstood, and was retired.
"It was a fabulous car – maybe one of the most beautiful ever – but it never performed quite right," Setzer told me. "Maybe with a little more effort, we could have done something very different."
After an aborted attempt to turn it into a rocket-powered exhibition car, the machine was shelved and later donated to the Don Garlits Museum of Drag Racing.
Foster with son Cole, Linda Vaughn, and Setzer in the winner's circle, where they spent a lot of time in the 1972-73 seasons
As my time with Setzer ran down – he was headed to a business appointment – I made sure that he knew that his name was etched into the memories and record books of many of us and shared some of the platitudes I had gathered.
Not long before his passing in March 2008, Foster said of his longtime friend, "Barry was a quiet, soft-spoken, intelligent man, a man of his word, and always a gentleman. A better car owner would be hard to find. It was a shame that Barry couldn't have kept going in drag racing. There's no doubt in my mind that he would have been a major player for many years, and he certainly would have been in contention for one of the first major corporate sponsorships. Racing with Barry was certainly the highlight of my career. Barry gave me the opportunity to prove my abilities as a driver and engine and clutch tuner."
In 2001, car builder Buttera called Setzer "one of my favorite, if not the favorite, customers I ever had. That was back in the days when you could try a lot of new things, and Barry encouraged that. Other people were very demanding, but Barry knew how to say please and thank you."
I asked Setzer to reflect on his short but wonderful time in the sport, and he, typically understatedly, said, "We made a pretty good splash there, didn't we?
"It was a great time in my life," he continued. "I enjoyed traveling around the country and meeting people and being exposed to a lot of different ideas and concepts. I tried to make it to as many races as I could and enjoyed it a lot. I enjoyed the people, especially Pat. Pat was like a brother to me. He was a great guy, and the fact that I've kept alive a relationship with his son, Cole, I think speaks for itself on how I felt about Pat.
"It is amazing," he agreed when I told him about the reverence fans like me still have for that car. "I don't follow the sport much anymore, but I took my car in to get it inspected in a little shop the other day, and the guy told me, 'I want you to know that you're still relevant.' That made me feel good."
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The Camping World Drag Racing Series will run on Friday, Saturday and Sunday at all other events (one qualifying session on Friday, two qualifying sessions on Saturday, and Final Eliminations on Sunday).
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AUG 18-19 Lucas Oil Series Divisional Event


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Il forte San Martino sorge a Genova, nell'omonimo quartiere. Situato sulla collina di Papigliano è oggi completamente circondato dal tessuto urbano.

Storia
Diverse proposte per la realizzazione di una fortificazione in questa posizione a difesa di Albaro e San Martino furono presentate fin dal 1771 ai responsabili delle fortificazioni della Repubblica di Genova.

Nel 1807, durante la dominazione napoleonica, il governo francese, sollecitato dal Genio militare, stanziò 180.000 franchi per la costruzione del forte, ma i lavori non furono mai iniziati.

Il progetto fu poi ripreso nel 1820 dal governo sabaudo, che diede inizio alla costruzione, terminata nel 1832.

Persa la sua funzione strategica primaria alla fine dell'Ottocento quando, a causa dell'espansione urbanistica della città verso levante, il piccolo rilievo su cui sorge finì per essere circondato dal tessuto urbano, nel 1889 sul piazzale antistante la caserma fu realizzata la Batteria San Martino, a protezione dell'imboccatura del porto e dello specchio d'acqua antistante.

Le postazioni di artiglieria furono smantellate negli anni trenta per far posto ad una batteria contraerea, composta da quattro cannoni da 76/45. Durante la seconda guerra mondiale, il 14 gennaio 1944, nel fossato sottostante il ponte levatoio furono fucilati dalle milizie fasciste e dalle S.S. otto partigiani come rappresaglia per l'uccisione di un ufficiale delle S.S. avvenuta il giorno prima.

Nel dopoguerra il forte fu abitato da famiglie di sfollati e infine completamente abbandonato nel 1952. Oggi è di proprietà demaniale e l'accesso è chiuso da un cancello. La struttura è in pessime condizioni e ha perso anche il ponte levatoio che permetteva l'accesso al forte, eliminato per impedire l'ingresso di estranei all'interno dei locali.

Descrizione
A differenza di altre strutture militari genovesi, il forte San Martino, il più moderno tra quelli costruiti nei primi decenni dell'Ottocento, non è in posizione dominante sulla collina, ma infossato nella stessa e completamente circondato da un fossato, oggi nascosto dalla vegetazione.

Si presenta come un grande terrapieno rettangolare, con una caserma su tre piani sul lato di ponente, con l'ingresso principale, accessibile attraverso il ponte levatoio, situato all'ultimo piano. Presso il bastione meridionale si trovava una polveriera, circondata da spesse mura.
La dotazione di artiglieria collocata nel terrapieno comprendeva quattro cannoni da 16 GR e quattro da 9 BR Ret, sei obici da 21 GRC Ret e due mortai da 9 Ret.
Il forte poteva ospitare 300 soldati, ai quali se ne potevano aggiungere altri 400 in caso di necessità.

La batteria fine ottocentesca, le quali strutture sono oggi inglobate all'interno di attività commerciali, era armata con quattro obici da 24 GRC Ret.

Bibliografia

Voci correlate
Forti di Genova
Fortificazioni
Regno di Sardegna (1720-1861)

San Martino
San Martino (Genova)

redpajama_set_name: RedPajamaWikipedia


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NNR
from TECHNOLOGY NETWORKS
Sensor Can Detect Scarred or Fatty Liver Tissue
News Dec 02, 2020 | Original story from Massachusetts Institute of Technology
About 25 percent of the U.S. population suffers from fatty liver disease, a condition that can lead to fibrosis of the liver and, eventually, liver failure.
Currently there is no easy way to diagnose either fatty liver disease or liver fibrosis. However, MIT engineers have now developed a diagnostic tool, based on nuclear magnetic resonance (NMR), that could be used to detect both of those conditions.
"Since it's a noninvasive test, you could screen people even before they have obvious symptoms of compromised liver, and you would be able to say which of these patients had fibrosis," says Michael Cima, the David H. Koch Professor of Engineering in MIT's Department of Materials Science and Engineering, a member of MIT's Koch Institute for Integrative Cancer Research, and the senior author of the study.
The device, which is small enough to fit on a table, uses NMR to measure how water diffuses through tissue, which can reveal how much fat is present in the tissue. This kind of diagnostic, which has thus far been tested on mice, could help doctors catch fatty liver disease before it progresses to fibrosis, the researchers say.
MIT PhD recipient Ashvin Bashyam and graduate student Chris Frangieh are the lead authors of the paper, which appears today in Nature Biomedical Engineering.
Tissue analysis
Fatty liver disease occurs when liver cells store too much fat. This leads to inflammation and eventually fibrosis, a buildup of scar tissue that can cause jaundice and liver cirrhosis, and eventually liver failure. Fibrosis is usually not diagnosed until the patient begins to experience symptoms that include not only jaundice but also fatigue and abdominal swelling. A biopsy is needed to confirm the diagnosis, but this is an invasive procedure and may not be accurate if the biopsy sample is taken from a part of the liver that is not fibrotic.
To create an easier way to check for this kind of liver disease, Cima and his colleagues had the idea of adapting a detector that they had previously developed to measure hydration levels before and after patients undergo dialysis. That detector measures fluid volume in patients' skeletal muscle by using NMR to track changes in the magnetic properties of hydrogen atoms of water in the muscle tissue.
The researchers thought that a similar detector could be used for identifying liver disease because water diffuses more slowly when it encounters fatty tissue or fibrosis. Tracking how water moves through tissue over time can reveal how much fatty or scarred tissue is present.
"If you watch how the magnetization changes, you can model how fast the protons are moving," Cima says. "Those cases where the magnetization doesn't go away very fast would be ones where the diffusivity was low, and they would be the most fibrotic."
In a study of mice, the researchers showed that their detector could identify fibrosis with 86 percent accuracy, and fatty liver disease with 92 percent accuracy. It takes about 10 minutes to obtain the results, but the researchers are now working on improving the signal-to-noise ratio of the detector, which could help to reduce the amount of time it takes.
The current version of the sensor can scan to a depth of about 6 millimeters below the skin, which is enough to monitor the mouse liver or human skeletal muscle. The researchers are now working on designing a new version that can penetrate deeper below the tissue, to allow them to test the liver diagnosis application in human patients.
If this type of NMR sensor could be developed for use in patients, it could help to identify people in danger of developing fibrosis, or in the early stages of fibrosis, so they could be treated earlier, Cima says. Fibrosis can't be reversed, but it can be halted or slowed down through dietary changes and exercise. Having this type of diagnostic available could also aid in drug development efforts, because it could allow doctors to more easily identify patients with fibrosis and monitor their response to potential new treatments, Cima says.
Another potential application for this kind of sensor is to evaluate human livers for transplant. In this study, the researchers tested the monitor on human liver tissue and found that it could detect fibrosis with 93 percent accuracy.
Synergistic Effect of Gallium Highlights Benefits of Molecular "Teamwork"
Chemists have demonstrated the value of "teamwork" by successfully harnessing the interaction between two gallium atoms in a novel compound to split the particularly strong bond between fluorine and carbon.
Eye Tests Predicted Parkinson's-Related Cognitive Decline 18 Months Ahead
Simple vision tests can predict which people with Parkinson's disease will develop cognitive impairment and possible dementia 18 months later, according to a new study by UCL researchers.
Gene Variant Identified as Stroke Risk Factor in Elderly Patients
A team of Geisinger researchers has identified a common genetic variant as a risk factor for stroke, especially in patients older than 65.
Analysis & Separations Diagnostics
Developing Successful In Vitro Diagnostic Assays
Ensuring Nucleic Acid Quantity, Quality and Integrity With Fragment Analyzers
Ocean HDX Spectrometer Plays a Critical Role in Virus Detection
SARS-CoV-2 Specific and Neutralizing Antibodies
Rapid, Cost-Efficient Sample Processing in Workflows
Simple, Cheap Test Can Aid Early Diagnosis of Colorectal Cancer


text:
Is lori petty lesbian
How much is Lori Petty worth?
Lori Petty net worth: Lori Petty is an American actress who has a net worth of $3 million dollars. Born in Chattanooga, Tennessee, Lori Petty initially pursued a career in graphic art, before shifting her focus to acting.
What happened to actress Lori Petty?
She may no longer be the 90s quirky bombshell that we remember her mostly for, but Petty is still around and still making moves in Hollywood. After her role in Orange Is The New Black, Petty picked up a role in a 2016 movie, Dead Awake. Since then, she also picked up a few guest roles in some TV shows again.
How tall is Lori Petty?
How old is Lori Petty?
56 лет (14 октября 1963 г.)
Does Lolly have schizophrenia?
Although her diagnosis is not named, it is possible that Lolly has schizophrenia, a mental health condition that can cause people to experience auditory hallucinations such as voices.
Where does Lori Petty live?
Actress Lori Petty was born in doublewide trailer in Chattanooga, Tennessee. But for the last 28 years, she's called Venice home. "I moved to Venice in 1990, when Abbot Kinney was called West Washington and you could ride your bike in middle of the street and there were no cars," says Petty.
Does Lori Petty have Huntington's disease?
Lori Petty has signed up to appear in House, reports Entertainment Weekly. The Tank Girl actress will appear in a multi-episode story arc as a patient suffering from Huntington's disease.
Who plays Lolly Whitehill?
Lori PettyOrange Is the New Black
You might be interested: Is joan baez lesbian
Does Ellen play in orange is the new black?
Is Ellen the Voice in Piper's Head on Orange Is the New Black? … DeGeneres revealed on her show that she is actually the mystery culprit, snacking on a light salad and a Sprinkles cupcake.
Who is Jeri in Gotham?
Lori Petty
Where did Lori Petty go to high school?
North High School1981
Is the poker house a true story?
Written by Petty along with longtime friend, David Alan Grier, THE POKER HOUSE is based on Petty's own true life stories. As she puts it, "The stories are 100% true.


text:
By Rishabh Bhandari, Quinta Jurecic
Friday, August 12, 2016, 3:09 PM
U.S.-backed forces battling the Islamic State stated on Friday that they had launched a final assault to flush the remaining ISIS fighters out of the city of Manbij. The Syria Democratic Forces, buttressed by U.S. airpower, said that today's assault would be the last operation in the campaign for the city in northern Syria. Located near the Turkish border, Manbij has been a critical gateway for prospective Islamic State fighters looking to join the so-called caliphate. Reuters has more.
According to Al Jazeera, fighting continues to rage in Aleppo between rebels and government forces, even during the daily three-hour ceasefires promised by Russia to allow humanitarian groups to access the war-torn city. Trucks carrying food were unable to enter Aleppo on Thursday because of intense bombardment. Russian warplanes continued to target Aleppo's medical facilities, among other public spaces, despite the Kremlin's promise of a three-hour daily ceasefire.
The Associated Press reports that Syrian government airstrikes hit the only hospital earmarked for women and children in rebel-occupied parts of Aleppo on Friday. A market and a village were also hit. The strikes killed at least 18 civilians, including activists, rescue workers, hospital staffers, and children. In response to the onslaught, German Foreign Minister Frank-Walter Steinmeier called on the United Nations to supervise humanitarian access into Aleppo, arguing that Russia's unilateral three-hour daily ceasefires are insufficient to avoid a humanitarian crisis.
The Associated Press also tells us that Russian airstrikes killed at least 20 civilians in an attack on the Islamic State's de facto capital of Raqqa on Thursday. Activists said the operation killed at least 20 civilians.
Meanwhile, discussions continue between Turkey and Russia regarding a proposed coordinated anti-ISIS bombing campaign. The two countries are working to strengthen their ties, which were frayed after Turkey downed a Russian plane that crossed into Turkish airspace last year. The Hurriyet Daily has more on the prospective counterterrorism partnership.
The United Nations is investigating evidence of a toxic gas attack on a rebel-held area of the Syrian city of Aleppo. Rebels said the attack was carried out by government forces using chlorine gas, killing four people and leaving many injured. The BBC has more, including footage of people experiencing difficulties breathing while receiving treatment in a Syrian hospital. The Guardian reports that the act of dropping chlorine on Aleppo would be a war crime if confirmed, according to UN special envoy Staffan de Mistura.
The New York Times takes a closer look at the Syrian regime's use of chlorine gas. Because of its widespread use for a number of legal purposes, chlorine was not one of the substances destroyed by the international community in 2013 when Syrian President Bashar al Assad agreed to join the Chemical Weapon Convention.
The Hill reports that the Pentagon will not reveal how many U.S. soldiers are actually deployed in Iraq and Syria. The U.S. government will only disclose the number of full-time troops deployed—about 3,825 in Iraq and 300 in Syria—but the number of troops on the ground, including temporary deployments, is much higher. Republican lawmakers accused President Barack Obama of using temporary deployments and frequent personnel rotations as a means of circumventing the caps on troop levels implemented by the president.
In the New York Times, Nick Kristof writes that the United States' failure to contain or end the ongoing civil war in Syria constitutes the gravest mistake of Obama's presidency. Kristof likens the crisis in Syria to the atrocities committed in places such as Bosnia, Rwanda, and Darfur, and predicts that the growing refugee problem will only feed further extremism.
As the Islamic State's losses on the conventional battlefield pile up, the Washington Post looks beyond the possible demise of ISIS to warn that new conflicts may emerge in Iraq between current allies. While Sunni extremism has unified a broad coalition of groups—including Kurdish peshmerga, Iraqi armed forces, Shiite militias, and some moderate Sunni groups—analysts warn that deep-seated disagreements over the distribution of power, money, and territory have not been resolved.
The New York Times reports that Islamic State fighters are still lurking in their former stronghold of Sirte, despite the organization's defeat by forces aligned with the internationally recognized Libyan government. But both city officials and military commanders said large swathes of the city have been secured by the government. Officials credited U.S. air support as a major factor in their swift victory but dismissed claims that British and U.S. special forces played a role on the ground as attempts to discredit the Libyan government as a puppet of foreign regimes.
According to Reuters, a U.N. envoy to Libya said support for the country's embattled unity government is "crumbling" as public dissatisfaction swells over the regime's inability to provide basic public goods. These grumblings have been exacerbated by an economy that is reeling from a weakening currency that is raising prices of needed imports.
Turkey's government now searching for several military officers and diplomatic staff posted overseas, who fled their posts in the wake of the failed coup and may be seeking asylum abroad, according to the Wall Street Journal. Turkey's pursuit of these exiles could further strain its already fractured relationships with its Western allies. At least one officer was based in Virginia and is already requesting asylum from U.S. authorities.
The Associated Press tells us that Ukraine put its troops on combat alert Thursday along the country's eastern border amid an escalating war of words with Russia over Crimea. Ukrainian President Petro Poroshenko issued the order after Moscow accused his country of sending several groups of "saboteurs" to carry out attacks in Crimea, killing two Russians. Kiev has denied these claims as "fantasy" and "a provocation." The BBC has more.
Reuters writes that the Kremlin has further ramped up the pressure by announcing war games in the Black Sea and convening President Vladimir Putin's security council. In New York, the U.N. Security Council held a closed-door meeting at Ukraine's request to discuss the growing tensions.
The United States is weighing another round of sanctions against Russia to punish the Kremlin for its alleged role in the hacking of the Democratic National Committee during the ongoing political season. Any commitment to increased sanctions would have to be paired with a public declaration that Russia was responsible for the attack. The Journal has more.
The Philippines wants formal negotiations with China to explore pathways to peace and cooperation, the Southeast Asian nation's special envoy, Fidel Ramos, said on Friday. Ramos, a former Filipino president, was speaking near the end of a trip to Hong Kong undertaken in a bid to rekindle his country's ties with China, which have been soured by the ongoing maritime dispute in the South China Sea.
Reuters reports that the Philippines are also in the midst of talks with Japan to obtain two large coast guard ships to help patrol the contested waters. Although Japan does not have a territorial claim in the South China Sea, it is involved in a related dispute with China over islands in the East China Sea. Beijing has warned that Tokyo's interference in the South China Sea will further destabilizing the region.
The Guantánamo parole board has cleared for release an Algerian captive who was for a time considered for prosecution as part of a Pakistan-based bomb-making cell, the Pentagon announced Thursday. The man, who received a letter of endorsement from one of the guards, said he intended to run a pizza parlor near his mother's home in Algiers. He is the 35th detainee approved for release among the 76 captives currently in the detention facilities.
The German government proposed a broad range of measures on Thursday to bolster security and combat terrorism, its strongest official response so far to two recent attacks by terrorists pledging loyalty to the Islamic State and a deadly shooting rampage in Munich. Many of the measures, which include closer monitoring of refugees and enhanced surveillance, seem likely to win legislative approval but have prompted concerns in a country that is deeply protective of privacy and civil liberties. A record 1.1 million foreigners migrated to Germany last year and the country received 442,000 asylum requests.
Police in Brazil have arrested two men suspected of supporting the Islamic State in the second phase of raids that earlier led to the detention of 12 people immediately preceding the Olympic Games. The men were arrested in Sao Paulo, the country's second largest city.
Pakistani lawmakers approved a cybersecurity bill that grants regulators broad powers to remove or block content they deem offensive or dangerous. Security officials defended the legislation as a necessary tool to combat terrorism, but critics allege that its vague language could be exploited to suppress free speech and unfairly prosecute dissidents. Reuters has more.
CNN fills us on violence in Thailand, where 11 bombs went off in five different provinces across the country. At least four Thai nationals were killed and 36 others were injured, including ten foreigners. No group has yet claimed responsibility. Thailand, which has been plagued by political instability, is approaching the one-year anniversary of a devastating bombing at a Bangkok shrine. The BBC has more.
Michael Knapp drew our attention to Russia's recent territorial claims in the Arctic.
Toby Levy assuaged our privacy concerns regarding the privacy threat Pokémon Go represents.
Benjamin Wittes flagged a first round legal victory for Twitter over the question of whether CDA §230 immunizes the company against civil lawsuits over its provision of services to terrorist groups.
Matthew Wein dissected and dismissed Donald Trump's proposed blanket ban of Muslim immigrants as both immoral and unfeasible.
Paul Rosenzweig highlighted the work of two researchers who discovered a security key that protects Microsoft devices and may help restart the encryption debate.
Quinta Jurecic is the Managing Editor of Lawfare. She previously served as an editorial writer for the Washington Post and as Lawfare's associate editor.
@qjurecic


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Computer-Based Drug Design
Precision Prevention
Tumor Dynamics
Tumor Dynamics: Predicting Cancer's Trajectory Using Tumor Atlases
Cancer is a dynamic disease that is unique to each patient. Tumor development and progression are complex, involving factors in the cancer cells themselves as well as multidimensional interactions between other cells and tissues in the body, which are shaped by a person's genetics and cumulative exposures. As cancer progresses, tumors typically become more heterogeneous, composed of diverse cancer and noncancer cells with different molecular characteristics and behaviors. This staggering complexity makes it difficult to predict how a person's cancer will progress and respond to treatment.
NCI is addressing this challenge by supporting research that is accelerating our understanding of the dynamics of tumor progression. For example, as part of the Cancer Moonshot℠, scientists are creating 3-D reconstructions of tumors and their evolution through the Human Tumor Atlas Network (HTAN), which consists of 10 interdisciplinary research centers across the country. HTAN brings together information about the cellular and structural makeup of a variety of adult and pediatric tumor types and premalignant abnormalities down to the single-cell and molecular level. In addition, NCI supports research to build and test new computational approaches to predict cancer development, progression, and response to treatment.
Technological advances, such as genetic sequencing of tumors at the single-cell level and spatial analysis of gene expression patterns across cells within a tumor sample, are enabling scientists to study tumors at unprecedented resolution. With these advances, researchers are exploring each tumor's set of genetic and molecular characteristics, including in the cells and molecules surrounding cancer cells, to create maps of a tumor and its microenvironment.
While each tumor is unique, scientists can begin to understand which genetic and molecular characteristics are linked to tumor behavior by comparing tumor data maps to each other and to patient outcomes. However, this requires processing and interpreting a lot of data. New mathematical approaches and computer programs—including artificial intelligence (AI) and deep learning—can be used to analyze tumor data and enable researchers to better define key transitions during cancer progression, such as premalignancy to cancer and primary cancer to metastasis.
Ending cancer as we know it includes a future where we can predict a tumor's trajectory based on a detailed profile of each patient's disease. Additional research investments coupling tumor atlases with advances in computer science and molecular techniques will ultimately enable precision prevention, treatment, and care strategies for patients.
Using Computer Science and Artificial Intelligence to Study Tumor Progression
Recent advances in data access, computing power, and AI methods are enabling a better understanding of tumor progression, from premalignancy to early cancer and from less to more aggressive cancer.
AI is no longer just fodder for science fiction stories. Instead, cancer scientists are using AI and machine learning to make sense of the large amounts of data being generated on the dynamics of tumor evolution. As noted above, these types of data include detailed molecular characteristics and physical features of single cancer cells, tumor images and other spatial data, and clinical information over the course of diagnosis and treatment.
Artificial intelligence (AI) is a computer's ability to perform a task in a way similar to that of humans, through a process of learning, reasoning, and acting based on computer program instructions. Machine learning and its subset deep learning are types of AI that learn by exploiting patterns in data.
As one example, an NCI-funded collaboration between researchers at Indiana University and the NCI Intramural Research Program applied innovative and faster AI techniques to reconstruct key features of tumor progression, a computational process that can be prohibitively slow. The researchers used deep learning methods to understand the evolutionary history of a tumor using measurements from single cells. Notably, the researchers were able to construct large "family trees" of tumor cells to infer the history of how tumors evolve over time. In the future, this approach should enable scientists to better understand how cancer forms, progresses, metastasizes, and responds to treatment, which can lead to new therapeutic targets and approaches.
There are still major hurdles to address before AI will reach its full potential in cancer research. One major hurdle, called the "black box" problem, is AI's lack of transparency. We don't fully understand how the computer uses patterns in the data to make decisions. With additional investments in AI design and implementation, researchers hope to establish transparent and reliable computer programs that can use tumor data input to help predict clinical outcomes for patients when making treatment decisions.
Compiling Data on Tumor Heterogeneity with Cutting-Edge Technology
Large data sets that represent the cellular and molecular diversity of tumor cells are the ingredients for AI tumor analysis. Tumors consist of cancer cells as well as immune cells, blood vessels, fibroblasts, other cells, and components that interact with the cancer cells.
The molecular characteristics of cells in a tumor differ from patient to patient and even among tumors in a single patient. And these characteristics can change over time, including in response to cancer treatments. Understanding tumor cell heterogeneity, and collecting data that capture this heterogeneity, is critical because the extent of molecular differences among tumor cells might affect whether it grows or not (its stability), its ability to evade the immune system, whether and where it spreads (metastasizes), and its susceptibility to treatments.
The heterogenous mixture of cells in a tumor has multiple molecular and physical features that scientists can observe. Collecting and analyzing this combination of data that describes cells is called multi-omics.
Multi-omics, the process of collecting and analyzing a combination of data that describes cells, provides a way to study tumor cell heterogeneity, and can be performed at even the single-cell level. Some types of data that scientists collect include:
genomics (DNA sequences in the cell)
epigenomics (DNA modifications that affect whether a gene is turned on or off)
transcriptomics (RNA sequences that cells use to make proteins)
proteomics (the set of proteins in a cell)
metabolomics (the products of cells breaking down proteins and nutrients)
Single-cell sequencing is a rapidly growing technique that allows scientists to compare the genomes and DNA products from each tumor cell. This effort builds on previous NCI-funded cancer genomic studies that relied on sequencing a whole tumor sample containing multiple cell types at a single point in time. Using single-cell technology, a recent NCI-funded study led by investigators at Memorial Sloan Kettering Cancer Center identified a subpopulation of small cell lung cancer cells—with unique genetic features and an immunosuppressed microenvironment—that is more likely to metastasize to other parts of the body. These findings have implications for developing future targeted immunotherapies for small cell lung cancer.
In the next frontier of cancer research, scientists are leveraging cutting-edge technologies to learn about the spatial anatomy of cancer and its molecular features. One such imaging technique uses repeated fluorescent labeling to identify a large set of cellular markers throughout a single biopsy. Imagine cutting a tumor into small sections and then using multiplex imaging to record many cellular and molecular features of each section at the single-cell level. Scientists are doing just that, and then assembling that information virtually to build a 3-D map of the tumor and its microenvironment. By mapping out heterogeneous tumor cells and their microenvironments, scientists are poised to identify cellular interactions and molecular characteristics that predict tumor behavior.
For example, NCI-funded researchers at Stanford University used spatial proteomics to characterize HER2-positive breast cancer collected before, during, and after treatment with neoadjuvant (presurgical) therapy. Typical tumor samples are an aggregate of tumor, immune, and connective or structural cells. By using spatial proteomics, they found that the number and kind of immune cells in the tumor changed during treatment for a subset of patients, and that increased levels of a single immune marker, called CD45, following initial treatment could predict response to the full course of therapy.
These results add to the groundwork for personalized medicine. Imagine tailoring a patient's treatment plan based on their tumor's molecular response to initial therapy, increasing the likelihood that treatment will lead to a favorable outcome.
In another study, NCI-funded researchers at the Oregon Health & Science University generated a comprehensive multi-omic analysis of a human cancer response to treatment. They analyzed blood and tumor biopsies from a patient with metastatic hormone receptor–positive breast cancer during multiple rounds of treatment. Samples included the primary tumor and three subsequent metastatic tumors over the course of 42 months. The researchers used the data to generate a spatial image atlas to identify how the patient's tumors responded to treatment and to identify patterns of tumor progression and mechanisms of drug resistance.
These studies offer a peek into the possibilities for precision medicine in the future, in which multi-omics data will help doctors optimize treatment decisions for their patients. More investments are needed to develop the next generation of technology to perform spatial analysis dynamically, at a larger scale, and more rapidly.
Studying the Role of the Tumor Microenvironment
Just as plants and animals respond to the demands of their environments, tumors also adapt to environmental pressures. Cancer scientists are increasingly thinking about tumors from an evolutionary and ecological perspective. New research aims to reveal how a tumor's microenvironment affects tumor growth, metastasis, and drug resistance.
The tumor microenvironment is made up of the cells and molecules that surround the tumor. For example, blood vessels feed the tumor and immune cells may prevent the tumor from growing or spreading.
Immune system function is an important factor in the tumor microenvironment. The immune system patrols the body to watch out for abnormal cells and can recognize and kill cancer cells—a capacity that has been harnessed by cancer immunotherapies. Scientists want to better understand how tumor cells interact with cells of the immune system so they can develop more effective immunotherapy and immunoprevention approaches. For example, researchers want to learn how and when precancerous tumors that progress to cancer, or cancerous tumors that recur after therapy, hide from the immune system.
In an NCI-funded clinical trial testing different drugs for early-stage HER2-positive breast cancer, doctors collected information about the tumor's immune microenvironment with each therapy. They found significant changes in the composition of surrounding immune cells 14 to 21 days after treatment. They found that an initial increase in cancer-killing T cells decreased by the time of surgery. In the future, this type of information could help determine the best timing for immune system–based interventions during breast cancer therapy.
Now, tumor atlases are being compiled to study the tumor microenvironment's role in the transition from premalignancy to invasive cancer—with an eventual goal to incorporate patient exposure data over time. This information could inform prevention and intervention strategies in the future.
For example, NCI-supported researchers at Stanford University and their collaborators observed a correlation between the tumor microenvironment and breast cancer development. Using surgical samples from patients, their study revealed that changes in the location and function of immune cells surrounding the tumor are associated with a shift from preinvasive abnormalities to invasive breast cancer.
Building on NCI-funded research on the tumor microenvironment, scientists have suggested tumor classification systems that may help doctors select the best course of treatment for individual tumors. These classifications are often based on the genetic makeup of the tumor. However, researchers have developed a classification system that is based on evolutionary and ecological principles, incorporating inherent traits of the tumor (such as tumor cell heterogeneity and rate of tumor change) and the ecology of the tumor's surroundings (such as blood flow and immune system response). A classification system that includes tumor and tumor microenvironment traits could aid the goal of precision medicine.
If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., "Tumor Dynamics: Predicting Cancer's Trajectory Using Tumor Atlases was originally published by the National Cancer Institute."


blueglue, 28 Feb 2012nothing is proved of what you said. let me remind what you have said . "thats why i s... moreyou don't know that shipments is the same as sales? of course you don't. you just lecture us on your english that mean nothing.
let me tell you in business, you don't recognize sales without shipment (except for long term construction contracts, different thing). when we say we have shipped the goods, then we will recognize sales.
Anonymous, 28 Feb 2012awesome news go for it :-Dsurely i will buy it!!
Anonymous, 28 Feb 2012I am so confuse... A lot of people who use android, blackberry, Iphone said that their phone w... morehaha..yeah..i did agree with you have said for nokia..i just a samsung galaxy tab 7,Nokia E7 and blakcberry 9900..first i told to you all,i did not lying anything about this.i wont told you the bad of android because i use an android tab to..but i just got dissapoint with this tab, its so lags at and when i open the web browser more than 5pages its always get off and im tired of it and wanna give it to my cousin because its useless for me, and i also will told you about the blackberry, i really hate this phone,its really slow when start, i bought it because i like this phone blackberr messenger, i never love the bb os because its like a java, really hate bb. And about the nokia..its lag too..but i always borrow this phone when i go to every where..the belle os is really friendly to use and its smooty than my android tab. And for you that never use belle please shut up..i can said the bad of android,iphone and nokia because i ever use it.
we actually have our own preferences on mobile phones.
other wants good browsing and so on.
AnonD-43988, 28 Feb 2012650 comments now..... Is it the highest ever for any article on gsmarena?nope its not the highest dude, its steve jobs death.. articles about nokia is always like this.
I am so confuse... A lot of people who use android, blackberry, Iphone said that their phone were smart... So what is the meaning of smartphone for you guys? Tell me? Why they all bashing with symbian (poor screen res, poor of ram, poor of UI, laggy, and many more).. Actually symbian is not that bad, poor screen res? In small screen there is no big difference between 640*360 and HD. Small of RAM, CPU, GPU? It's because symbian don't need such a useless hardware symbian can maximize the three of that, poor of UI? It's not in new symbian belle, Laggy? All OS even ios sometimes get laggy, the one who said ios is always smooth are completely liar... So all android fans and IOs fans, tell me what is the meaning of smartphone for U?
OMG, Awesome phone and this must have all amateurs and profesional photographers.
Nokia 808 is the STAR OF MOBILE WORLD in 2012 forget SG3 and iphone5...Nokia is the best..
Can't hide from the facts trollers, it's amazing technology, not copied but hard work and innovation, Only from Nokia!
Is it the highest ever for any article on gsmarena?
blueglue, 28 Feb 2012i was not aware that we need to consider the so called asha, 1101 etc phones into the smartpho... morewill u two stop?its getting boring..just buy the phone u love.end of story..we get ur point..if you will not love this phone,den dnt pursade other not to buy this magnificent camera phone,just stick 8 cores battery sucking phones..
Wow.. my droid tablet can handle 38mp camera shot.. and can download and save it.. its a 9mb file guys.. so happy..
nokia is best, 28 Feb 2012you don't learn don't you..... lemme give you some facts 30% of world mobile users are from... morei was not aware that we need to consider the so called asha, 1101 etc phones into the smartphone categories. Really, are they also smartphones?
If what ever you said is correct why does symbian has only 20% or less share worldwide? whom are you trying to convince with your illogical math?
And what would 20% of 5.6 bil end up as? If nokia is ruling all of India, China & Europe markets, why did it fall? where are the sales dude? every report including nokia themselves have acknowledged the rapid downfall of symbian from 73% in 2006 - around 17% in 2011. and only 1.6% of WP share , where do your so called "majority" stand?


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Japanese Cooking Shows To Explore the Food Art Culture
If you want to start learning about Japanese food art, watching Japanese cooking shows is a good way to understand and appreciate the art of cooking. The Japanese cooking style is famous for its elegant and detailed preparation. Each dish requires the close attention of the cook. Because, according to Japanese people, every dish is an art. Some recipes do not require many ingredients. However, the cooking step and presentation are the most important. Japanese food culture is so unique and enjoyable.
Japanese Cooking Shows on Netflix
1. Midnight Diner-Tokyo Stories
2. Samurai Gourmet
3. Kantaro The Sweet Tooth Salaryman
4. The Final Table (Japanese episode)
Other Japanese cooking shows inspire you to try Japanese cuisine
5. The Solitary Gourmet (Kodoku no Guru)
6. Wakakozake
7. Ms. Koizumi Loves Ramen Noodles (Ramen Daisuki Koizumi-san)
Midnight Diner is a cooking show from Japan about a restaurant in a hectic area of Tokyo. The restaurant opens at midnight. In contrast to usual restaurants, the restaurant's chef, mainly known as "The Master," includes four simple dishes: pork and vegetable noodle soup, beer, and sake. However, based on the requirements of the guests, the Master can create any delicious recipe for his customers. Sometimes the guests bring the ingredients themselves.
Each episode is about customers, including salarymen, prostitutes, and even yakuza gangsters, as The Master will cook a specific dish as requested by the guests. It is a feast table for the cooking enthusiast to learn new recipes.
As the show focuses on cooking, you can see The Master preparing the main dish. Usually, the food he cooks for the guests involves the story behind it and is the favorite dish of the episode's featured character. The show usually ends with a philosophical life lesson from the featured character's story.
Midnight Diner is one of the well-known Japanese cooking shows from which many spin-offs have been created in other countries, such as South Korea's Late-Night Restaurant and China's Midnight Diner.
Japan is famous for its samurai history. In Samurai Gourmet, the brave and courageous samurai are presented in a relaxed and funny way. A retired salary man, Takeshi Kasumi finds his happiness in exploring food haunts in his neighborhood. However, he does not eat alone, accompanied by a wandering samurai who appears in his awareness. Thanks to the Wandering Samurai, Takeshi Kasumi is eager to try new experiences and food he hasn't eaten.
This cooking show from Japan is not mainly about the food. It provides a means of overcoming anxiety and self-consciousness. In the first episode, Takeshi Kasumi is shy about drinking a beer on a weekday. However, Wandering Samurai would do it. He follows his make-believe idol and gains his courage as a true samurai.
One of the Japanese cooking shows, contributing to the sweet desserts, is Kantaro the Sweet Tooth Salaryman. The show is about the gourmet adventures of a salaryman. However, in his middle age, the lead character, Kantaro Ametani, has a sweet tooth, even though no one could believe it due to his grave, focused, hardworking personality. He is a salesman at a publishing house who quit his former job so that he would have more time to explore the sweet shops and review them on his dessert blog.
Who could believe that a reliable and efficient man at work is also the person who can sneak out to various dessert shops in Tokyo?
Although the show is fiction, the locations and the stores are authentic. Therefore, you can put it on your list if you visit Tokyo in the future and try out Kantaro's endorsement.
View more: Top 7 Chinese Cooking Shows To Explore Chinese Cuisine
If you like cooking competitions, this is the Japanese chef cooking show for you!
The Final Table is an American cooking competition show that puts international teams of professional chefs against each other.
Japanese cuisine is featured in episode eight, where the chefs prepare kaiseki (Japanese haute cuisine) for the judges, featuring Japanese model Hikari Mori, comedian Yuji Ayabe, and food writer Akiko Katayama.
This competition show has a second round, The Final Plate Challenge, where a chef selects a secret ingredient and the teams have to make the best creations. In this episode, the Final Plate Challenge includes chef Yoshihiro Narisawa, the chef of the two-Michelin-starred Les Créations de Narisawa in Tokyo. Which ingredient does he choose for the show? Watch it to see how each team highlights the dishes!
Eating lonely is an eating culture in Japan. It is not surprising if you see many people eating alone in restaurants. Gorō Inogashira (played by Yutaka Matsushige) is an example. Gorō Inogashira loves eating alone. The viewers follow a man who is a middle-aged salesman. Every day, he communicates with different people about the trouble situations, such as renting a new office or meeting with an over-talkative woman who wants to buy teacups. But after 10 minutes of his daily life, the rest of the show devotes to the delicious foods and his thoughts as he eats alone.
The remark of the show is not about the food, but it is his expressions while he eats. Looking at his face, viewers can see the satisfaction that the food has served him.
The series is based on the manga created by Masayuki Qusumi, the same one who made Samurai Gourmet and Sunshine Sento-Sake. Remarkably, at the end of each episode, Qusumi visits the real-world restaurant that Gorō ate in the show and enjoys the same meal.
You also like: Best Indian Cooking Shows That Will Leave You Spellbound
If The Solitary Gourmet (Kodoku no Guru) is one of the Japanese cooking shows calling you to dine alone, Wakakozake is for the fan of eating and drinking alone. Wakako (played by Rina Takeda) is a 26-year-old office worker. After working, she likes drinking and eating alone. Like Gorō, the content follows the storyline and the focus is not all about the food. Wakako is a woman who enjoys selecting the right sake to combine with the salted grilled salmon. Wakako also enjoys the time at home, where she cooks for herself.
Wakakozake is a show where you can enjoy eating and drinking after a working day. This show is about the daily life of usual office workers interested in eating and drinking. In one episode, Wakako thinks, "I like liquor not because it makes me forget, but because it makes me notice." It's about taking time and appreciating the small pleasures in life.
See more: The Best Cooking Shows In France You Should Watch Next
Ramen lovers can't miss this show. Koizumi (played by Akari Hayami) is a transfer high-school student who catches the attention of her classmate Yū due to her beauty. Yū wants to become a friend of Koizumi. Unfortunately, her love for ramen is more prominent than making friends.
Koizumi is a master of ramen-eating techniques. She impresses the group of men while eating her ramen bowl. The show attracts the viewers through the seriousness of Koizumi before eating the ramen, cracking her wrist, and tying back her hair. She also inspires the watchers with her exhaustive knowledge about ramen, from the difference in regional style to the unexpected method for making instant ramen as good as traditional ramen restaurants or her research of the best ramen restaurants.
The show highlights the ramen in a fascinating approach that makes you want to eat ramen while enjoying the series. Moreover, the information about ramen in this series is as impressive as Koizumi's expression for ramen.
Japanese food culture is about traditions and etiquette. The attitude of Japanese people toward the food is a noticeable element that makes Japanese cooking shows appealing. There are many movies where you can learn more about the food and the respect of Japanese for the food and ingredients. Besides delicious dishes, Japanese shows are delightful due to the meaningful stories behind each movie. Follow Thecookingmovie for more food movies and shows.
best cooking show on netflixbest cooking showsCooking show from Japancooking showsJapanese chef cooking showJapanese cooking showsjapanese food moviejapanese movie about food
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Enterprise Fire Protection
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Risk and Compliance Management
Managed Security Services (MSS)
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Be first to read the latest tech news, Industry Leader's Insights, and CIO interviews of medium and large enterprises exclusively from Enterprise Security Mag
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Editor's Pick(1 - 4 of 8)
Julie Cullivan, SVP Business Operations & CIO, FireEye
Ken Kojima,Chief Information Security Officer at California Department of Corrections and...
Alexander Schuchman, Chief Information Security Officer, Colgate-Palmolive
Brenden Smith, Chief Information Security Officer at FirstBank
Jay Leek, Managing Partner & Co-founder of SYN Ventures
Jake Flomenberg, Partner, Wing Venture Capital
Dr. Jacques Benkoski, General Partner, U.S. Venture Partners
The Responsibilities of an Information Security Leader
Joshua Cloud, Director of Information Security, NFI Industries
As information security leaders, we believe it's our duty to ensure that our organizations understand the risks associated with technical decisions, provide the best guidance to mitigate these risks, and be the agents of change toward a more secure future. People depend on us to have a strong understanding of the security space, and for us to maintain our own personal integrity in the board room, for our employees, and for our customers. We need to remember to focus on the "must-haves", identify new risks due to the changes in the business, leverage the latest technologies, and be honest and ethical even when no one is looking.
The modern user wants the freedom to be able to work from anywhere in the world, on any device, and, often, on platforms of their choosing. Mobile device management software and containerization capabilities are an absolute must-have to help organizations maintain some semblance of control over their data on these devices. When configured properly, this software can greatly reduce the likelihood of any compromise of information confidentiality in the event of a device being stolen/lost or an employee leaving the organization. It's important to understand the impact of such an event to right-size your organizations investment on these tools.
Multi-factor authentication (MFA) is an excellent security tool to help reduce the impact of compromised credentials. However, these systems often create additional and sometimes excessive friction to the normal login process. As a result of this friction, widespread adoption in organizations is often challenging. A possible alternative to across-the-board MFA is to implement some form of adaptive step-up authentication. This approach will challenge the user for additional factors of authentication only when certain higher risk functions are being attempted. In fact, some banks are already doing this. When you attempt to initiate a large money transfer, the bank may require you to type in a one-time SMS-delivered passcode to further confirm your identity. This is less friction over-all, and still provides a significant reduction to risk.
IoT device proliferation and their notoriously immature patch and vulnerability management practices present a somewhat unique challenge. These devices are often in very close proximity to our most prized data, yet there is little confidence the endpoints themselves are not littered with exploitable vulnerabilities and/ or vehicles to pivot from which are accessible by someone in the product's supply chain. Isolating these devices from both internal and external connectivity with the strictest of technical controls, such as firewall policies and access-control lists, is an appropriate and recommended first step to mitigate most of the risk. Innovative, connected security technologies which use machine-learning to learn and analyze behavior real-time are also good to layer on to ensure your security professionals can be made aware when something is amiss.
Our responsibilities as information security leaders don't end at the technical stack. For many of us, we are in regulated environments which help drive certain aspects of our programs. We often help enforce less popular policies and controls designed to ensure compliance and alignment with executive leadership. We have tough conversations with the board when gaps are discovered. We're trusted with access to very sensitive information where confidentiality is imperative. Many of us use tools today which collect massive amounts of data on our employees and customers as well. It's critical that we maintain the absolute highest standards of ethics for ourselves, our staff, and our peers. In this modern world of big data and an increased reliance on digital engagement, we need to maintain focus on confidentiality, integrity, and availability—for both our information and ourselves.
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Joshua Brown, VP and Global CISO at H&R Block
Cloud Technologies and Cyber Security
Enterprise Security.
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text:
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redpajama_set_name: RedPajamaGithub


On January 13th, Prof. Yang Shiqin, former President of Harbin Institute of Technology visited the School of Mechanical Engineering of HEBUT, and talked about the school development. Prof. Lv Zhiwei, vice president of HEBUT, and Prof. Li Tiejun, dean of the School of Mechanical Engineering of HEBUT, both attended the meeting.
Professor Yang visited the Robot and Intelligent Equipment Research Center of HEBUT and spoke highly of the core research team and research orientations of the center. He said that the orientation, such as intelligent construction, intelligent manufacturing equipment, health care robots and special robots, are in line with the China's future development and serve as a scientific frontier, which helps promote the development of mechanical engineering and related disciplines.
Prof. Li Tiejun reported on the running of the school and the development of the research center. In his remarks, the school will seize the opportunity to carry out "double first-class" construction, attract excellent talents, and train first-class talents. At the same time, in response to the needs of the country and industry, the school will give full play to the potentials of the existing talents and team advantages, carry out cutting-edg research, and actively implement industry-university-research cooperation to contribute to the regional social and economic development.