text:
Magdalens
Encyclopedia Volume
Free World Class Education
FREE Catholic Classes
The members of certain religious communities of penitent women who desired to reform their lives. As time went on, however, others of blameless reputation were also admitted, until many communities were composed entirely of the latter, who still retained the name of Magdalens, or White ladies from the colour of their garb. It is not known at what period the first house was established, the date of foundation of the Metz convent, usually given as 1005, being still in dispute. Rudolph of Worms is the traditional founder of the Magdalens in Germany (Mon. Germ. Script., XVII, 234), where they were in existence early in the thirteenth century, as attested by Bulls of Gregory IX and Innocent IV (1243-54), granting them important privileges. Hélyot quotes letters addressed by Otto, Cardinal of the Title of St. Nicholas in Carcere Tulliano, Apostolic Legate in Germany, granting indulgences to those contributing to the support of the German Magdalens. Among the earliest foundations in Germany were those at Naumburg-on-the Queis (1217), and Speyer (1226). Gregory IX, in a letter to Rudolph, prescribed for the penitents the Rule of St. Augustine , which was adopted by most of the Magdalens, though many of the German houses later affiliated themselves to the Franciscan or Dominican Orders. Institutions of Magdalens still exist, e.g. at Lauban (founded 1320) and Studenz, for the care of the sick and old. Few of the German convents survived the Reformation.
Houses of the Magdalens were soon founded in France, Belgium, Italy, Spain, and Portugal. The first foundation in France was made at Marseilles about 1272 by Bertrand, a saintly man who associated with himself in his work of rescuing fallen women other zealous men, later constituted a religious congregation by decree of Nicholas III, under the Rule of St. Augustine. In 1492 the eloquence of the Franciscan Père Jean Tisserand influenced a number of women to turn from evil ways and embrace a life of penitence. Five years later Jean-Simon, Bishop of Paris, prescribed for them the Rule of St. Augustine and drew up special statutes for their direction. From the beginning of the seventeenth century these Magdalens of Rue St-Denis were all women of stainless lives. Among other prominent communities of Magdalens were those at Naples (1324), Paris (1592), Rome, where Leo X established one in 1520, Seville (1550), Rouen, and Bordeaux.
The Madelonnettes , members of another Order of St. Mary Magdalen, were founded in 1618 by the Capuchin Père Athanase Molé, who, assisted by zealous laymen, gathered a number of women who desired to reform their lives. Two years later some of these were admitted to religious vows by St. Francis de Sales, and were placed successively under Religious of the Visitation, Ursulines, and Sisters Hospitallers of the Mercy of Jesus, and from 1720 under Religious of Our Lady of Charity. The constitutions, drawn up in 1637, were approved by the Archbishop of Paris in 1640, and the house was erected by Urban VIII into a monastery. Two branch foundations were made at Rouen and Bordeaux. The order comprised three congregations, (1) the Magdalens proper, who had been deemed worthy of being admitted to solemn vows, (2) the Sisters of Saint Martha , who, for some reason, could not undertake the obligation of solemn vows, and were bound by simple vows only, and (3) the Sisters of St. Lazarus, public sinners confined against their will. Each congregation had a separate building and observed a different rule of life. Sisters of St. Martha were admitted to the ranks of the Magdalens after two years novitiate. This order is no longer in existence.
Rosaries by Catholic Online Shopping
Pray The Rosary -Spanish
Pink Swarovski Pearl Sterling Silver Rosary
@ $111.97
Search Search the Entire Catholic Encyclopedia
Browse by Catholic Encyclopedia Alphabet
Saints A to Z: A
Prayer for Parents (#3)
Stay up to date with the latest news, information, and special offers.


The Annandale Area Friends of the Library have donated $300 toward the purchase of "We Play Here" kits for use by young library visitors.
GRRL is seeking $3,000 to buy twelve kits. These will be added to the twenty the library previously obtained through a Playful Learning In Libraries mini grant from the Minnesota Department of Education, State Library Services. Once the new kits are bought, the library system will own 32 kits, so each branch in the 32-library system will be able to have one at all times.
The kits are for use by families with preschoolers. Each kit contains a variety of toys selected to increase parent/child engagement through play. Toy selection was based on the five practices of Every Child Read to Read: talking, singing, reading, writing, and playing. For example, one of the reading kits includes two books, a puppet, alphabet puzzle mats, alphabet blocks, an alphabet magnet set and activity mats, and other materials. The kits will be rotated from library to library to keep the contents fresh for children and families who use them.
The Annandale Friends made their donation through the Wish List fundraising tool on the library's website. Wish List is a vehicle for crowdfunding as well as the purchase by individuals of books and other items for the library's collection.


There are no tours in Vilanova i la Geltrú yet.
Planning a travel to Vilanova i la Geltrú? Login to create your trip plan so the guddies can offer you their tours!
There are no travelers coming to Vilanova i la Geltrú yet.


A small Syrah vineyard at the Hacienda Zorita Organic farm. They mainly use this wine as a rub for one of their cheeses.
Long ago before my country decided to become foolish and voted by a tiny majority to leave the EU, I was invited to Spain as a guest of the Concordia Family Estates, which is a group of companies that is really on the rise. It's run by some very passionate people and it shows. It all started with the Hacienda Marqués de la Concordia in Rioja Baja and over the years they have added other wineries, labels and brands to their stable. Bodegas Lagunilla was first in 1994 and since then Marqués de Monistrol have joined the group, allowing them to make some fine Cavas. Federico Paternina added another famous Rioja bodega, while with Bodega Rioja Santiago they acquired the second oldest producer in the region – it was founded in 1870. In Rioja they also own Viña Alarde, which produces more modern styles of value for money wines.
Further afield they also own an amazing estate in Andalusia called Ándalus which even grows Petit Verdot.
I'll be honest, this company – or these companies – have so many strings to their bow that it is very hard to get a grip on it, but it doesn't really matter, because everything was wonderful and each component made sense.
The beautiful Hacienda Zorita photo – courtesy of the hotel.
Storks are a common sight in these parts, this one is on the roof of the Hacienda.
I was invited visit the Hacienda Zorita, which is a charming boutique hotel that belongs to the company, they call it the Hacienda Zorita Wine Hotel & Spa. It is a few kilometres outside the beautiful cathedral city of Salamanca and it really is idyllic. It dates back to 1366 and was both the hospitality buildings for the local Dominican Monks and their farm, complete with water mill to make their bread – amazingly they say that Christopher Columbus – Cristobal Colon – came here when he was trying to raise funds for his first voyage.
My very comfortable room at the Hacienda.
This is a wonderful part of the world and the Tormes River flows right by the Hacienda before winding the 40 or so kilometres to the border with Portugal where it flows into the Duero / Douro at Fermoselle in Arribes del Duero.
Not content with being in hotels and wine, the company is also into fine food production. Many of their wine estates also grow olives and make superlative oil, but they also have an organic farm where they produce some stunning cheeses and the finest jamon and chorizo that I have ever tasted. They have recently started producing balsamic vinegar too, I got to try it and it is shockingly good, the older barrels were almost solid like toffee, but it isn't yet ready to put on the market.
The balsamic vinegar ageing in different size casks, the older it is the smaller the cask as it evaporates.
Not far from Femoselle and the frontier with Portugal they also have the Hacienda Zorita Natural Reserve, which is a wine estate in the wilds of the Arribes del Duero wine region and the Arribes del Duero Natural Park which also covers the Douro Valley over the border in Portugal. Traditionally this area grows Juan Garcia, a grape that is not particularly loved, but that can make very good things when treated right. However at Zorita they decided to base their wines on Tempranillo, which is permitted in the DO. In addition, acting under advice from Richard Smart, they also decided to plant Syrah, and while this is not permitted in the local DO, it seems to perform very well indeed.
Hacienda Zorita Natural Reserve Unamuno Vineyard – there's a billiard table at the top of that tower!
The estate from the top of the tower.
The estate is named in honour of Miguel Unamuno, who was a great writer and philosopher of the late nineteenth and early twentieth centuries. He was Rector of Salamanca University and travelled widely in the Duero Valley writing about his journeys.
The presumably much repaired Roman Bridge over the Tormes River at Ledesma, just think how many people will have crossed that over the centuries. My ancestor William Sadler served under Wellington in the Peninsular War and some of Wellington's army marched this way in 1812, so I might not have been the first member of my family to walk on that bridge.
70% Pinot Noir with 30% Monastrell aged 48 months on the lees.
It was made at Mas Monistrol, the home of Marqués de Monistrol.
Available in the UK from Amazon for £37.50 for a case of 3 bottles.
I am a big fan of Rueda wines and think it is the most reliable white region in Spain. At the very least the wines never disappoint and the Verdejo grape is a terrific grape that is not unlike Sauvignon Blanc, but usually a tad richer and more herbal.
This wine is basically a Verdejo with 5% Sauvignon blended in. The grapes were picked at night to retain the freshness. Cold fermented using aromatic yeast and then aged for 3 months on the lees.
The nose has rich aromas, with a touch of olive oil, olives, ripe peach and a touch of apricot skin, citrus, some a little light pineapple too.
The palate has quite a rich mouthfeel, textured, and again with an olive twist, peach skin and even a little spritz. It has a rich, fat style, with nectarine succulence and a slight feel of tannin, perhaps from skin contact. The palate is lightly creamy and is balanced by the zesty quality of lemon rind and grapefruit pith – 88/100 points.
Available in the UK from Ocado for £10 per bottle and from Amazon where a case of 3 bottles is £22.57.
100% Syrah aged for 18 months in a mixture of French and American oak barrels.
Unusually this offers bright, red fruit notes, as well as being lightly floral, a little earthy, with some tobacco and a little sweet vanilla too.
Very supple palate, with lots of rich red fruit and good refreshing acidity making it feel svelte and poised. There are some attractive fine grain tannins and the oak makes it gently smoky. Avery attractive wine, the sweet vanilla works well and lovely juicy fruit is nicely kept in check. Nice tingling spicy finish blanks the bright fruit, it was very attractive to drink, but will become even more complex in 3 or 4 years time.
Available in the UK for about £15 a bottle from Ocado and Amazon.
100% Tempranillo aged for 24 months in French and American oak barrels.
This has a great nose, lifted, peppery and savoury, with some dark fruit, especially dark cherry. Earthy notes balance all that seductive power making it really attractive.
Opens up in the mouth with a supple texture, still peppery, spicy, polished velvety tannins and lots of smoky, tobacco, vanilla oak.
Very attractive stuff, but wow, this is a big modern, almost New World style Rioja – 90/100 points.
The grapes are grown in the Abascal Vineyard, which is next to Vega Sicilia, one of the most famous wines in the world.
This is pure Tempranillo – known as Tinto Fino in Ribera del Duero and it spends 18 months in American and French oak.
The colour is black, dense and opaque.
The nose is similarly 'yuge' with rich sweet notes of dark fruit, balsamic and fresh earth, black olive and bitter chocolate.
The palate has loads of fat and richness, with cocoa, mocha and ripe black plum flavours. Rich and concentrated, fleshy and succulent, but there is some balancing freshness there too, the tannins are ripe and the it is dominated by a mixture of velvety fruit and sweet umami characters. A monster of a wine, but I really liked it – 90/100 points.
The garden of the Hacienda just outside my villa.
All in all I had an amazing time in a wonderful place and came back relaxed and restored. It wasn't their fault that my country went completely mad on the night I got back – June 23rd 2016, a day that will live in infamy.
It is an astonishingly beautiful part of the world, the hotel was a total joy, sitting in the garden there was one of those moments that I felt totally at peace, just staring into the velvety Spanish night sky. The wines were splendid, the food excellent, our hosts charming and for a brief moment all was right with the world.
Do visit if you can and if that isn't possible, try some of their wines, cheeses or jamon – it's all available by clicking here.
Olive tree at the organic farm.


text:
Home » Health News » Why Men Are Hit Harder by the New Coronavirus
Why Men Are Hit Harder by the New Coronavirus
Radio station owner Carl Goldman has been in quarantine since February 3, a slog that began with confinement on the now-infamous Diamond Princess cruise ship in Japan. Ultimately, Goldman, age 67, was diagnosed with COVID-19 and has since whiled away days in various medical settings, isolated from his wife, Jeri. Despite being with her husband until he began to show symptoms, however, Jeri remains free of COVID-19 and has been able to return home to California.
This difference between men and women in the expanding COVID-19 epidemic isn't confined to one couple. Along with posing increasing threat with age and some co-existing conditions, it may hit men slightly harder than women. Why, though, is a mystery that scientists are trying to pin down.
The first hints at this male-biased effect emerged in studies from China. One report describing early cases said that 106 men were diagnosed with COVID-19 for every 100 women. In another study from China of 99 patients with COVID-19 who were hospitalized with pneumonia, 67 were men. Men in China also have been dying at greater rates than women, at 2.8 percent compared to 1.7 percent among women.
The imbalance crops up elsewhere, too. In an analysis of patients testing positive in Singapore, 41 were men and 26 were women. In Italy, the skew is even more stark, with men making up three of every four diagnosed cases.
This coronavirus is not alone in hitting men harder than women. In the 2003 outbreak of SARS, COVID-19's cousin in infectious disease, being male was linked to more severe disease. Men were more likely than women to die in that earlier outbreak, too.
Although some people like to joke about men complaining more than women about the same disease, research suggests that more serious factors are in play. Eng Eong Ooi, deputy director of the Emerging Infectious Diseases Program at Singapore's Duke-NUS Medical School, says that although we don't know why men seem to have greater risk for COVID-19, several explanations are plausible.
What scientists suspect
One possibility, he says, is that differences in hormone levels between men and women could underlie some of this bias. These differences can affect how men and women respond to infectious disease, vaccination, and cancer.
For example, says Ooi, hormones present in greater concentrations in women may suppress levels of the protein that lets the novel coronavirus into our cells.
Other possible explanations, researchers have suggested, include average differences in how men and women spend their days. Men in China, for example, smoke more than do women, which might make them more vulnerable to COVID-19 disease.
Some studies also point to a role for activities that skew toward one sex or the other, clustering them together on a regular basis, allowing for disease spread. Finally, women lag behind men in some of the other risk factors for more severe COVID-19, including cardiovascular disease.
Pinning down relevant factors will take more research and more time, says Ooi. Meanwhile, he says, "the prevention measures remain the same: good hand hygiene."
That takes us to another factor that could be in play. The U.S. Centers for Disease Control and Prevention has reported that even though everyone knows to wash hands after using a public bathroom, only 65 percent of women do so and an even more scandalous 31 percent of men do.
New parents are consumed by worry and fret about their baby's health every hour
Elsa Pataky Says Her Workout Are Fueled By 'Accidental Intermittent Fasting'
What do normal labia look like? Sometimes doctors are the wrong people to ask
Beyond Burgers Are Not Healthier Than Beef Burgers And That's Just The Truth
Are, by, Coronavirus, Harder, hit, men, New, the, Why
How to live longer: Best diet to increase life expectancy – proven in two new studies
Vitamin B12 deficiency symptoms: Is weight gain a sign you could be lacking B12?

redpajama_set_name: RedPajamaCommonCrawl


text:
Unilever Nepal Limited launches new campaign called '#UNMUTE, End the Silence on Domestic Violence'
KATHMANDU, March 10: Unilever Nepal Limited (UNL) has launched a new campaign called "#UNMUTE, End the Silence on Domestic Violence" coinciding with the International Women's Day, 2021.
PM Oli pledges to emphatically address VAW related cases
March 8, 2021 11:34 am
KATHMANDU, March 8: Prime Minister KP Sharma Oli has said that the government of Nepal has brought into implementation the 'National Strategy and Action Plan to End Gender-Based Violence and Gender Empowerment' so as to empathically address the issues related to violence against women.
Final rites of Bhagarathi Bhatta performed
BAITADI, Feb 19: The final rites of Bhagarathi Bhatta, who was murdered after rape, were performed in Baitadi on Friday.
Police make public prime accused of Bhagarathi Bhatta's murder in Baitadi
KATHMANDU, Feb 17: Police on Wednesday made public a youth man who was allegedly involved in the murder of a teenager Bhagarathi Bhatta in Baitadi district.
Bibeksheel Sajha Party urges authorities to book those guilty of raping and murdering teenage girl in Baitadi
KATHMANDU, Feb 7: Bibeksheel Sajha Party on Sunday urged the authorities concerned including the local administration to bring to justice the guilty in the alleged rape and subsequent murder of a 17-year-old girl, Bhagarathi Bhatta of Dogadakedar Rural Municipality, Baitadi district.
Indian police launch probe as two adolescent girls from Nepal raped in UP
KATHMANDU, Dec 15: Indian police have launched a probe into an incident in which two adolescent girls from Nepal were found allegedly kept at a farm against their will and raped for nearly two months at a village named Pilibhit in the Indian State of Uttar Pradesh, media reports said.
PM Oli urges to be sensitive towards protecting rights of violence survivors
In a message released on the occasion of the 16 Days of Activism against Gender-based Violence, PM Oli reaffirmed the government's efforts to optimize the resources of the State and enhancing living standards of women to help build a prosperous society thereby securing their rights and welfare.
Man held on charge of raping 14-year-old girl in capital
KATHMANDU, Nov 18: Police have arrested a person on the charge of raping a girl in Chandragiri Municipality.
As many as 1,673 cases of violence against women recorded in the past six months
More than nine cases recorded daily on average in the past six months
I thought there was liquor in the bottle: Acid attacker
KATHMANDU, July 24: An Indian national arrested on the charge of throwing acid on a 22-year-old woman in Bafal said that he didn't know there was acid in the bottle. "I was asked to throw the liquid in the bottle on the girl. I thought it was liquor as it was a liquor bottle. I had no clue that the bottle had acid in it," Munna Mohammad, an Indian national, told during police interrogation.
Two arrested for throwing acid on 22-year-old woman in capital
KATHMANDU, July 24: Police have arrested two persons for throwing acid on a 22-year-old woman at Sitapaila in Kathmandu on Thursday evening.
A 22-year old woman attacked with acid in Kathmandu
KATHMANDU, July 24: A 22-year-old woman was attacked with acid by an unidentified person at Sitapaila in Kathmandu on Thursday evening.
Survivors of domestic violence are forced to "compromise" with abusive husbands
Despite brutal physical assaults from husband and family members, domestic violence survivors are compelled to reach a compromise with perpetrators due to poor economic status and family and social compulsions.
India hangs 4 men convicted for fatal New Delhi gang rape
NEW DELHI, March 20: Four men sentenced to death for the gruesome gang rape and murder of a woman on a New Delhi bus in 2012 were hanged Friday, concluding a case that exposed the scope of sexual violence in India and prompted horrified Indians to demand swift justice.
Ending the stigma of menstruation
Globally, International Day for the Elimination of Violence against Women is celebrated every year on 25 November. On this occasion, the United Nations launched sixteen days of activism to advocate for gender equality and elimination of all forms of violence against women and girls. Statistically, Nepal falls at the bottom on gender equality index and more than one in five women have experienced some form (physical, mental, sexual) of violence in their lifetime.
Durga Devi in digital violence maelstrom
KATHMANDU, Nov 28: The 16 days of activism against gender-based violence is currently unfolding in over 180 countries, and Durga Devi from a small village in western Nepal feels the connection as she has been at the receiving end for so long.
Cruel, inhuman, unpardonable
Her face was dipped into boiling fish curry simply because she was not cooking fast enough. And then the perpetrator, none other than her husband, locked her inside and left to bring ointment, which he never did. Fearing that his dastardly act would become public and he would have to face the consequences, he ran away the next morning.
Lawmakers draw attention of govt over recent incidents of acid attacks on girls
KATHMANDU, Sept 8: Lawmakers have drawn the attention of the government over the recent incidents of acid attacks on girls.
Courtroom drama against child marriage goes on in Banke
BANKE, Aug 17: A campaign against child marriage and violence against women (VAW) is going on in rural settlements in Banke with the help of a courtroom drama.
June 23: 6 things to know by 6 PM today
Your daily dose of missed important news of the day.
Rape cases increase in Karnali State
BIRENDRANAGAR, June 23: The Karnali State in the past nine months reported 116 cases of rape which is nearly a double compared to the incidences occurred in the corresponding period last year.
Journalists come together against VAW
CHAINPUR, June 23: A journalists' network has been formed to work for mitigation of all kinds of violence against women in Bajhang district. The network has been formed at the initiative of Sancharika Samuha Nepal.
Six rape cases reported daily in Nepal
KATHMANDU, June 15: The number of reported rape cases continues to rise despite strict laws in Nepal, the latest data from the Nepal Police said.
Speakers voice concern over growing cases of violence against women across the country
KATHMANDU, June 9: Speakers have expressed serious concern over growing cases of violence against women across the country.
May 28 : 6 things to know by 6 pm today
Violence against women growing at alarming rate: police
KATHMANDU, May 19: Chief of the Metropolitan Kathmandu Crime Range Uttam Raj Subedi said on Sunday that violence against women is growing at an alarming rate with an adverse effect on their mental and physical health.
May 7: 6 things to know by 6 PM today
Woman allegedly beaten to death by her husband
RAUTAHAT, April 1: Police on Sunday arrested four individuals accused of murdering a woman Rautahat district.
Govt committed to ending VAW: Speaker Mahara
DANG, Dec 6: Speaker at the House of Representatives Krishna Bahadur Mahara has said the government was serious to end all kinds of violences against women.
Nirmala a test case for Nepal govt: UN Special Rapporteur
KATHMANDU, Nov 30: Visiting UN Special Rapporteur on Violence against Women, its Causes and Consequences, Dubravka Simonovic, said the rape and murder of 13-year old Nirmala Panta is a test case for the Nepal government.
6 rape cases a day in first quarter of fiscal year
KATHMANDU, Nov 28: In the four months since Nirmala Panta, the 13-year-old schoolgirl in Kanchanpur district, was raped and subsequently murdered, the issue of rape and other gender-based violence has remained the most talked-about issue. Civil society groups, informal social media groupings and several other networks launched awareness and pressure campaigns aimed at sensitizing the public about violence against women and girls.
Campaign against GBV kicks off from Muktinath Temple
MUKTINATH, Nov 25: The Federation of Community Forest Users' of Nepal (FECOFUN), Gandaki Province, has launched a campaign against gender-based violence (GBV) from the premises of famous Muktinath Temple in Mustang.
Sajid Khan steps down as 'Housefull 4' director over allegations of sexual harassment
In a post on Twitter, Sajid said he was taking the "moral responsibility" to step down till he can allay the allegations.
Over 30 schoolgirls in Bihar beaten up by goons for resisting sexual advances
The incident took place in Supaul district in Bihar. The girls are in critical condition. A mob of over two dozen people thrashed them with sticks after they caught a youth writing lewd comments on the hostel wall and scolded him.
In defense of porn
It was a love at first bite. The bite of freedom guaranteed by the internet. The freedom, more than the pornography.
Govt plans to start new campaign against VAW
CHITWAN, Oct 3: The government plans to start a new campaign to end domestic violence, Minister for Home Affairs Ram Bahadur Thapa said. This will succeed previous campaigns the KP Sharma Oli government has initiated over the past couple of months.
Violence against women in a month: 170
KATHMANDU, Sept 28: A total of 170 cases of violence against women occurred in the country in a month.
Various issues highlighted in HoR meeting
KATHMANDU, Sept 6: Lawmakers speaking during the special time in the meeting of the House of Representatives raised various issues ranging from the need of managing the country's oldest library well to taking strong measures to reduce violence against women.


text:
Cybrexa Therapeutics to Present First Data and Unveil Details for its alphalex™-PARP Inhibitor Lead Candidate CBX-11 at AACR Annual Meeting 2019
NEW HAVEN, Conn., March 18, 2019 (GLOBE NEWSWIRE) -- Cybrexa Therapeutics, a biotechnology company developing a new class of cancer therapeutics through its alphalex™ tumor targeting platform, today announced that Vishwas Paralkar, PhD, Chief Scientific Officer of Cybrexa, will present the first set of preclinical data supporting its alphalex™-PARP inhibitor lead candidate, CBX-11, at the American Association for Cancer Research (AACR) Annual Meeting 2019, being held March 29 – April 3 in Atlanta, Georgia. At the meeting, the Company will unveil the FDA-approved poly ADP-ribose polymerase (PARP) inhibitor conjugated in CBX-11.
CBX-11 combines Cybrexa's proprietary alphalex™ tumor targeting technology with an already-approved oral small molecule PARP inhibitor. CBX-11 will be evaluated in combination with DNA damaging chemotherapy for the treatment of patients with solid tumors that lack homologous recombination deficiency (HRD). The company remains on track to submit its Investigational New Drug (IND) application for CBX-11 by the fourth quarter of 2019, with a Phase 1 clinical trial evaluating CBX-11 in combination with chemotherapy anticipated to begin in the first quarter of 2020.
Details for the poster presentation are as follows:
Targeting solid tumor acidic microenvironment with an alphalex PARP inhibitor
Permanent Abstract # 2981 / Poster #3
Session: Diagnostics, Biomarkers, and the Tumor Microenvironment
Date and Time: Tuesday, April 2; 8:00 am – 12:00 pm EST
Location: Georgia World Congress Center, Exhibit Hall B, Poster Section 11
Presenting Author: Vishwas Paralkar, PhD, Chief Scientific Officer of Cybrexa
"This marks the first set of preclinical data supporting our lead candidate CBX-11, which we formally announced at the beginning of the year," said Vishwas Paralkar, PhD, Chief Scientific Officer of Cybrexa. "Our alphalex™ tumor targeting technology represents a novel approach to enable the synergistic efficacy of a PARP inhibitor and chemotherapy administered at full dose. We are excited to share these compelling data and take the opportunity to unveil the composition of CBX-11, especially given the current development landscape and high profile of PARP inhibitors."
About the alphalex™ Technology Platform
The Cybrexa alphalex™ technology platform enables the delivery of small molecules across the cell membrane under low pH conditions, which is a universal feature of cancer cells. As a result, alphalex™ technology – which consists of a novel peptide, linker and small molecule anti-cancer agent – allows for antigen-independent, intracellular delivery of small molecule anti-cancer agents directly into the tumor cell. View a video of the mechanism of action of the technology at http://www.cybrexa.com/our-technology/.
About Cybrexa
Cybrexa is a privately-held biotechnology company dedicated to developing an entirely new class of cancer therapies using its alphalex™ platform to deliver anti-cancer agents directly into tumor cells. The Company's lead candidate, CBX-11, an alphalex™-PARP inhibitor combination, is in preclinical development with advancing plans to initiate clinical development by 1Q 2020. Cybrexa was founded by physician-scientists, and has an experienced management team that has built numerous successful life sciences companies and raised hundreds of millions of dollars in venture capital. For more information about Cybrexa, please visit www.cybrexa.com.
The Ruth Group
Lee Roth
lroth@theruthgroup.com
Kirsten Thomas
kthomas@theruthgroup.com


text:
Reliving memories of Christmas 1975
The Digger goes back 35 years to recall the Christmases we enjoyed in the 1970s
A miniature `Basil Brush' figure from the early 1970's era. He made an appearance on television over the 1975 Christmas period on December 27th.
1N the run-up to Christmas, 35 years ago, The Ulster Star ran a painting competition for the 6 to 10 year old age group.
Six lucky runner ups would win Disney yo-yos and the main prize that year would be 'Raving Bonkers'. Anyone remember that? It was a game consisting of two nine and a half inch high robots in a boxing ring. It was a highly valued prize, priced at £7.75. Undoubtedly it brought a lot of pleasure to the eventual winner who resided in the Edenvale Gardens, Ballymacoss area of Lisburn.
In 1975 the sum of £7.75 would have bought you a guitar from Evans Musical in Bridge Street. Perhaps you were the proud owner of one of the stylophones they had on sale that year for £13.50.
Santa Claus visited Lisburn on Saturday 29th November at loam and he could be seen at 'Super Crazy Prices'.
This would be a good time to ask him for your new Raleigh Chopper. Had you have had the foresight to hold onto it, a collector would today be handing over between £60 and £100 for the bicycle. Other popular bicycles included the Raleigh 18 and the Dawes Kingpin.
If you were having turkey that year for Christmas dinner then you would have been paying somewhere in the region of 45p per pound. For those with rheumatic pains an illicit bottle of the 'crateur' for a rub, manufactured in the hills of Tyrone or the Glens of Antrim was for sale between £1.50 and £2.50 per bottle.
Children frantically unwrapped presents to find a wide variety of toys that year. Prams and trikes ranged from between £3.40 and £6.60. For those who had become tired of the wooden guider on pram wheels, a new go-kart was available for £16.80. Other popular toys included jigsaws, rocking horses, spinning tops, Playskool dolls house and fifteen piece tea-sets.
What a pity we hadn't have taken more care of the toys and their boxes! An Action Man 'Talking Commander' figure recently sold for £160. A similar Grenadier Guard figure sold for £125. Starsky and Hutch figure dolls from 1975 are now fetching £50 each.
Other popular toys from that era now worth in excess of £50 include the Dr. Who Dalek and the Lego Wild West Scene. Santa, however, had always made his magical journey to provide us with toys for playtime and not to be unloved, unwrapped and confined to the attic.
There were a plethora of new annuals hot off the press for 1976 on sale for about 70 pence. They included Basil Brush, Beezer, Black Beauty, Bunty, Cub Scout, Dad's Army, Dandy, David Essex, Diana, Dr. Who, Hotspur, Judy, Lion, Magpie, Mandy, Marvel, Music Star, Oor Willie, Osmonds, Pink Panther, Popeye, Rupert Bear, Score, Shoot, Space 1999, Sparky, Spiderman, Tiger, Tom & Jerry, Topper, Twinkle, Victor and The Wombles - to name but a few! Some of the annuals, in good condition are now worth over £10.
Some people invested £6 in a "Wombles Radio" and would be tuning in on Christmas Day to Radio 1 to listen to a half hour programme of carols introduced by Cliff Richard. At 2pm on Radio Ulster listeners could join Walter Love, who was on a visit with the 2nd Battalion of the Royal Irish Rangers at Hemer in West Germany.
The family could settle down in front of the newly acquired colour 22 inch television which would have cost approximately £230 or could have been rented for £6.99 a month.
They had three channels to chose from. Broadcasting commenced on Christmas morning at 9am with Ragtime on BBC 1. Other programmes on BBC 1 included the Christmas Morning service, Rod Hull & Emu, Laurel & Hardy, Billy Smart's Circus, The Wizard of Oz, Bruce Forsythe, Some Mothers do 'av them, Morecambe and Wise Xmas Show Butch Cassidy & the Sundance Kid and The Good Old Days.
All three TV stations broadcast the Queen's speech at 3pm. The Bay City Rollers featured in Top of the Pops number one show hosted by Tony Blackburn and Noel Edmonds. The popular tartan clad heroes also had their own show on Ulster Television on Christmas Day. Several days before Christmas they been playing to fans in Belfast. It was reported than more than 60 young girls fainted at that concert.
One of the later television programmes broadcast on Christmas night by BBC 2 was titled "Presents past, or the art of the tin toy." It was a nostalgic look at Victorian and Edwardian tin toys and undoubtedly conjured up memories with grandfathers in 1975. It will not be long before grandfathers are watching nostalgic television programmes featuring Airfix kits, Action men and Scalextric!
The Digger can be contacted via The Ulster Star office or by email: diggerarticle@hotmail.com.


text:
Homenewslow odds high odds 5 tips around europe this weekend 150122
Low Odds, High Odds: 5 Tips Around Europe This Weekend - 15/01/22
Liam Bewsher
Fri 14 Jan 2022 15.07
Juventus vs Udinese (Low Odds): Paulo Dybala to Score First - 9/2
On Saturday in Serie A, Juventus take on Udinese in a battle of fifth against 14th, with Massimiliano Allegri's side just three points behind Atalanta who occupy the final Champions League place.
The last meeting between these two sides came on 22nd August in what was notably Cristiano Ronaldo's last appearance in a Juventus shirt. The Match Resulted in a 2-2 draw with Argentinian forward Paulo Dybala scoring the opening goal of the match after just three minutes.
Dybala has been arguably Juventus' star man since the Portuguese striker left for Manchester United, scoring nine and creating four assists in 19 matches, averaging a goal every 144 minutes, hence why he is priced at 9/2 to score first once again at the expense of Udinese.
Serie A Goalscorer Tips
PAULO DYBALA TO SCORE FIRST @ 9/2
PSG vs Brest (High Odds): PSG to win -5 Goal Handicap - 20/1
This weekend's Ligue 1 action sees Paris Saint-Germain host Brest at the Parc des Princes in a meeting of first against 13th in the standings.
Mauricio Pochettino's men are 11 points ahead of Nice in second place, having scored 40 and conceded just 18 in 20 matches in France's top flight. Meanwhile, Brest are 13th, letting in 31 in 20 games.
With an attacking trio of Kylian Mbappe, Neymar and Lionel Messi is must be stated that five goals aren't out of the realms of possibility, especially when considering that PSG thumped Brest 4-2 away from home back in August as Ander Herrera, Mbappe, Idrissa Gueye and Angel Di Maria all got on the scoresheet, without Messi or Neymar at their disposal.
Ligue 1 Goal Handicap Tips
PSG TO WIN -5 GOAL HANDICAP @ 20/1
FC Koln vs Bayern Munich (Low Odds): Bayern Munich to win -2 Goal Handicap - 2/1
The next tip is a low odds one from the Bundesliga, as league leaders Bayern Munich travel to sixth in the table FC Koln.
Julian Nagelsmann's men have scored 57 goals in 18 matches, conceding 18 along the way, meaning that they average 3.1 goals per game and with Robert Lewandowski averaging a goal every 77 minutes with 20 in 18 league matches, it will be a tough ask for Koln to stop them.
The first meeting was Nagelsmann's first league match in charge of Bayern which will have likely caused some teething problems as the champions were still adapting to the 34-year-old's tactics, but, this didn't stop them from managing all three points in a 3-2 victory, as a Lewandowski goal and Serge Gnabry brace settled the outcome.
Bundesliga Goal Handicap Tips
BAYERN MUNICH TO WIN -2 GOAL HANDICAP @ 2/1
Atalanta vs Inter Milan (High Odds): Lautaro Martinez to Score First & Inter to win 2-1 - 66/1
Atalanta go toe to toe with Inter Milan at the Gewiss Stadium on Sunday in an exciting clash in Serie A that sees first take on fourth.
When these two sides met in late September at the San Siro, Inter managed to rescue a point, having initially taken the lead in the match thanks to a thumping Lautaro Martinez volley, before falling behind to goals by Ruslan Malinovskyi and Rafael Toloi, but, former Manchester City man Edin Dzeko earned them a draw with a poachers finish from close range with 19 minutes to go.
Martinez has scored 11 goals and created two assists in 24 matches, seeing the former Racing Club man average a goal every 145 minutes. The 24-year-old also has a good record against Atalanta, scoring three in five appearances against them.
Serie A Goalscorer & Correct Score Tips
LAUTARO MARTINEZ TO SCORE FIRST & INTER TO WIN 2-1 @ 66/1
Real Madrid vs Athletic Bilbao (Low Odds): Real Madrid to win & BTTS - 11/5
In the Supercopa de Espana final, Real Madrid and Athletic Bilbao face off at the King Fahd International Stadium in Saudi Arabia with Los Blancos coming in as favourites.
In terms of La Liga context, this would be top of the table against ninth, with Carlo Ancelotti's side being the dominant force in the league at present, seeing them sit five points clear of Sevilla in second-place.
Real have scored 45 and conceded 18 so far in the league this campaign, showing that they are free-scoring. To get to the final of the Super Cup, Real beat Barcelona 3-2 thanks to goals by Vinicius Junior, Karim Benzema and Federico Valverde, whilst Bilbao scraped past Atletico Madrid 2-1 with Yeray and Nico Williams scoring late goals to send them to the final.
These two sides last met on December 22nd where there were three goals in the first 10 minutes of the match at the San Mames, as Karim Benzema put Real into a 2-0 lead after seven minutes, before Oihan Sancet halved the deficit to make the scoreline 2-1 with that score remaining as the full-time result.
Spanish Super Cup Match Result & BTTS Tips
REAL MADRID TO WIN & BTTS @ 11/5


Christmas. New Year's Eve. Thanksgiving. They're all about spending quality time with our family and friends. But holidays are just as much about delicious food and drinks. AND A LOT OF IT. So how do we keep our cores tight, energy thriving and skin glowing? What can we do to not lose what we've been working all year long? How do we keep our healthy (and thus happy) selves shining bright?
Ánd appetizers, ánd a 3-course meal, ánd a cocktail, ánd sweets, ánd dessert, ánd some chocolates. I'm so sorry love, but you'll feel so much better if you choose one or two, and politely say "no" to the rest.
Don't go with "No thanks, I'm trying to stay healthy during the holidays." as you might make others feel less happy with their eating habits. But try a "Oooh, your dessert looks absolutely delicious! But that main course we just had was so awesome I'm going to have to pass!". Your hosts will certainly not mind.
You shouldn't feel pressured into eating things that make you feel worse or trigger a good dose of food guilt. Know what you love and kindly decline what isn't your thing. Stop apologising for it. Simply smile and celebrate on.
I'm sure you can come up with some dream items of your own! And you'll be all set to stay on your health game in the coming year.
Christmas morning? Feeling hangover? Need to get ready for a party? Still make some time to exercise, even if it's just half an hour of do-it-yourself-at-home-yoga or just go for a quick walk or run. On these days it's even more important to keep moving in order to make sure our bodies keep processing any toxins and sugars.
Best would be to work out before you go to any party or dinner: any "bad stuff" will be stored in your muscle cells, not in your fat cells, which makes it waaaay easier to get rid of afterwards, and also to break down in your liver.
Your first drink should always be non-alcoholic.
Drink a glass of water with each alcoholic beverage.
Not more than 1 beverage per half hour.
Depending on how much you can handle, try not to have more than 3 alcoholic drinks over the whole evening.
Challenge yourself a little extra and go for a complete non-alcoholic eve! And while you're at it, why not create the most healthy & delicious mocktails (non-alcohol cocktails) and make a few for everyone.
Think of it this way: no hangover the day after, no regrets about drunk-dialing your ex, and you've proven yourself and everyone else that you can easily be the light of the party (+ having endless energies for dancing) while being completely sober!
Last but not least: as everyone seems to forget their boundaries – and indulge in whatever they want "because of the holidays" – it's even harder to be the only one politely refusing sweets or desserts. And watching everyone else enjoy their drinks while you sip your glass of water doesn't help either.
So find yourself a health-buddy who wants to keep on track just as you are! Helping each other through the tougher times and knowing someone goes through the same as you are, makes it so much easier. Even if you don't attend the same parties together, you can still text each other the occasional: "Dance soberly until the crowd wants what you are having :)" or "We are the master of our cravings ;)".
And when you do go for that piece of warm chocolate cake, make sure you are enjoying every crumble to the fullest and stop feeling guilty afterwards. You'll digest it a 100 times better.
Now you're all set to stay your healthy self during these tempting-filled days! No need to worry about staying in shape, easily keep on shining as you always do and enjoy this beautiful time of the year!
What are your healthy holiday tricks? Do you have any healthy gift ideas to add to the wishlist? Or a slightly embarrassing story about that year you drank a little bit too much? We'd love to hear all about it in the comment section below.


My father, Albert McSweeney — better known as Mack — worked as a porter in Covent Garden Market for most of his adult life.
In this photograph, my father is pulling a barrow and looking to his left. This was probably as a precaution against traffic, but it is equally possible that he was on the lookout for Old Bill in the unlikely event police were doing their job and collaring villains.
My father often described his working day as one spent ducking and diving.
To do him justice, an ironic term given his uncanny ability to avoid the clutches of the law, requires something considerably more than a passing mention, and so my essay A Memoir of a Kleptomaniac attempts to paint a fuller picture.
Alfred Hitchcock made use of the market's light-fingered activities to great effect for one scene in his film Frenzy. You can read more about this here.
When I was young, my mother would occasionally take me to see him at work. He would place me on his barrow, along with hessian sacks of vegetables and wooden crates of fruit. Then he would pull me up and along Bow Street, or across the cobbled stones of the Hall Yard, which is now buried beneath the Royal Opera House Souvenir Shop.
In the summer of 1971, I worked in the market as a porter. I was a university student at the time, and as green as an English lettuce.
Howard Chapman* was foolish enough to employ me. The firm was situated on Long Acre on a site now occupied by Russell & Bromley shoe shop.
*The Vestey family owned Howard Chapman. They also owned the Dewhurst butchery business.
Work began at 6 a.m., whereupon the foreman would take his breakfast in the Essex Serpent aka The Snakepit. As a result, he was drunk when he returned at 7.
The Snakepit was sited on 6 King Street. Like Howard Chapman, it is now a shoe shop.
The market was in constant motion all morning. But by mid afternoon it resembled a ghost town, only to spring back to life in the early evening when theatre and opera goers would descend on the area.
My father also worked as stagehand in a number of theatres, as did many porters. I did too.
During Spring and Summer the market would operate on Saturday mornings. Sunday of course was a day of rest, and one certainly needed it, unless of course one turned out for a local football club. What happened to that boundless energy? I knew several porters who had successful careers as amateur footballers.
Harry Hutchins, (see below) was a very talented player, as was my father who turned down terms with QPR following the end of WW2, during which time he played for the Royal Navy. His reasons? Being a professional footballer in those days did not pay enough. Even more shocking is my grandfather's rejection of professional terms with Chelsea when he left the army at the end of WW1, for the very same reasons.
My working life as a porter was short and not exactly covered in glory. My party trick was to upend loaded trolleys of fruit along the length and breadth of the market. How I hated that sharp downhill left turn leading from Floral Street onto Garrick Street.
Meanwhile, miscreants went about their daily business.
One of these gentlemen employed a number of disguises.
When confronting an Italian or a Spanish truck driver, he would don a black beret and a striped T-shirt. Then, in a most appalling cod-French accent, he would invite the driver to adjourn to a nearby greasy spoon for café au lait. Not that Frank's Cafe ran to anything more than Nescafé.
Meanwhile the rest of the gang set about emptying the dupe's truck.
If the driver was French, then a suitably dressed Italian would be there to help. The extraordinary thing was that so many drivers fell for it.
I have used this tale of ingenuity in my book A History of Murder.


To optimize the images for your website, application or blog is very important for the performances. I recommend to use GIF images if possible and the same size for every images of your posts or articles. That's because It can be much easier to maintain your files and update them in any case. We need to be patient to do a good job but we all will be satisfied at the end. There are many tools and websites that let us to optimize our images online like Optimzilla. But if we have dozen of files and images the job can be very difficult and we cannot optimize our images manually.
We need to install our image optimizers for our operative systems. I use only png, gif and jpg files so I have installed these the optimizers only for these file extensions: It seems strange because we need to run exe files to optimize our images. Don't worry: the tool will not run any executable files if the optimizer does not exists. Remember to put your vendor directory outside your root path in production or in your shared hosting! This is very important for your security.
Download these extensions and simply copy the executable files in a known directory. In my Windows 10 I have installed Cygwin and I have copied the optimizers in the bin directory C:\cygwin64\bin to make them available. All available optimizers are listed in the github repository of the main project. This is the project with our main dependencies.
Now we must configure Yii2 to let the framework know about the new extension: I have found this github repository before but the direct installation did not work for me and I have simply copied the controller and the service in my console project.
An excellent tool was implemented to do an excellent work and save a LOT of time for you. I hope it will be useful for someone. Enjoy!


Below is our thorough response regarding the proposed amendments to NEPA. We would like to give a special thank you to Noemi Lujan Perez, VP of Government and Media Relations, ECO Diversity Media, for drawing our attention to this issue as the environment is a pertinent, but often overlooked, feature of the housing industry, as well as for her assistance in writing our response with her expert knowledge of the field.
This letter contains Women in the Housing & Real Estate Ecosystem's (NAWRB) comments on the National Environmental Policy Act (NEPA), Forest Service, USDA, Advance Notice of Proposed Rulemaking (ANPR) and request for comment published on January 3, 2018. 83 Fed. Reg. 302.
Created in 2010, NAWRB is a leading voice for women in the housing ecosystem. NAWRB is dedicated to providing women the tools and opportunities for economic growth and expansion, while advocating and promoting women-owned businesses. NAWRB is the only third-party industry-specific certifier of Women-Owned Businesses (WOB) and Minority Women-Owned Businesses (MWOB) in the housing economy. NAWRB provides a unique platform for uniting Women in Housing and Women in Government including educational training on contracting opportunities both government and private, to expand our members' business growth.
4. Ways the Agency might expand and enhance coordination of environmental review and authorization decisions with other Federal agencies, as well as State, Tribal, or local environmental reviews.
A. NAWRB's Interest in Efficient NEPA Environmental Analysis NAWRB members are active collaborating partners with green and sustainable corporations, brands, and engaged in the housing ecosystem.
B. General Comments The NEPA process as conducted by the Forest Service and other federal agencies would benefit from change to be more efficient and timely to meet NEPA's objective of facilitating reasonably informed decision making regarding proposed federal agency actions with significant environmental effects. There are numerous ways that the Forest Service can revise its current NEPA regulations codified at 36 C.F.R. Part 220 and related Forest Service Manual and Handbook NEPA provisions to achieve this goal.
Changes to the Council on Environmental Quality (CEQ) regulations codified at 40 C.F.R. §§ 1500-1508 and the regulations of other federal agencies who are involved with national forest programs and projects will also help procedures more efficiently, and are hopefully underway, but the Forest Service need not await such changes to update its own regulations. In revising its NEPA regulations, the Forest Service should also address NFMA forest plan revision, amendment, consistency, and resource requirements.
Further changes to the Forest Service planning regulations at 36 C.F.R. Part 219 and objection process regulations at 36 C.F.R. Part 212 may be needed to fully implement the NEPA and related process efficiency improvements that are needed.
5) Increased use of categorical exclusions (CEs) from NEPA where appropriate.
NAWRB members' experience reflects that the processing of applications for leases, permits, and other Forest Service authorizations is often delayed because it and other federal licensing or regulatory agencies participate in the NEPA and related permitting processes sequentially rather than simultaneously. Moreover, there is usually not an overall schedule, with enforceable timelines for deliverables from the agencies, that is adopted, or accountability for missing due dates in a project schedule. In addition, some project opponents seek to delay projects through appeals that lack merit.
All of these problems can be remedied or alleviated through updated regulations and other administrative actions. Finally, special attention should be focused on providing CEs for forest and watershed health projects designed to improve water flow and quality, and to implement measures that prevent or reduce the risk of destructive forest fires or insect and disease infestations, or that rehabilitate burned or infested areas.
• EISs should be reserved for analysis of proposed actions that are expected to result in significant environmental impacts.
2. Consultation regarding effects on historic properties and cultural resources under the National Historic Preservation Act ("NHPA") and other protocols should be coordinated with the NEPA process, and at an early stage involve the State Historic Preservation Office and any interested affected Tribes so that qualified historic and cultural resources are protected as appropriate without excessive delay in process.
The Forest Service should provide direction encouraging contracting and otherwise partnering with state and local agencies and adjacent landowners and managers to complete relevant studies and reports and provide other data, information, technical and local expertise, and knowledge for NEPA and other environmental analysis. WUWC members are in many instances major, knowledgeable owners or managers of adjacent lands and resources.
In conclusion, this rulemaking is an opportunity for the Forest Service to address on a meaningful scale our comments above and those of others who support cost-effective national forest management. The WUWC looks forward to continued dialogue and collaboration as the Forest Service continues the rulemaking process.
We appreciate the opportunity to provide these comments. If you have any questions regarding our comments, please contact Desirée Patno, CEO & President of NAWRB, Desiree.Patno@www.nawrb.com, 949-559-9800.
This entry was posted in Great Articles, NAWRB Magazine, News and tagged NEPA, US Forest Service.


Age-related macular degeneration (AMD) is one of the main causes of poor vision in senior patients. This condition manifests itself in a distortion when looking at straight lines and in a decreased ability to read. The first signs (drusen) can sometimes be detected at a younger age during an eye fundus examination. Drusen are deposits of cholesterol and fats in the vicinity of the macula. Affected patients are prescribed food supplements containing lutein, zeanxanthin and vitamin E. Later on in life, these patients may develop macular degeneration. Patients will be susceptible to tiny haemorrhages from newly-formed blood vessels in the membranes at macular level. The treatment consists of photodynamic therapy (PDT) and possibly an intravitreal injection containing a special product that will counter the new formation of blood vessels.
This treatment is used in patients suffering from "wet" macular degeneration (AMD). In wet AMD, protein and haemorrhages in the macula and a swelling of the retina are detected. Patients suffering from AMD are intravenously injected with the dye Verteporfin (trade name Visudyne) and the macula is then treated with a diode laser. This procedure takes half an hour and is performed twice a year. Recent articles have shown that the combination of PDT and intravitreal injections with anti-VEGF (vascular endothelial growth factor) products offers the best chance of success. Patients who had difficulties reading beforehand will once again be able to see close up as a result.
Macular degeneration or macular oedema is treated by injecting specific medication (Avastin, Macugen, Lucentis) into the corpus vitreum. These injections are administered under sterile conditions in the theatre at the clinic. Patients are given three injections at 6-weekly intervals. Following the injection, you must apply anti-infective and antibiotic eye drops to the eye. Risk of infection is minimal, though, two days after the procedure, we will need to see you again to measure your eye pressure and to check for any signs of infection.


text:
El Parque Nacional de Ilha Grande es un parque nacional brasileño ubicado sobre el río Paraná, entre los estados de Mato Grosso do Sul y Paraná. El mismo abarca la Ilha Grande (isla Grande en portugués), llamada así por ser la mayor isla fluvial del río Paraná y diversas islas circundantes de menor tamaño. Fue creado el 30 de septiembre de 1997 y abarca una superficie de 78.875 ha.

Flora y fauna
El parque se encuentra en un área de transición entre el ecosistema del cerrado y el de la selva paranaense y posee varias endémicas y/o en peligro de extinción.  Entre la fauna terrestre se encuentran especies como el ciervo de los pantanos, el yacaré overo, el yaguareté, el tapir y el  oso hormiguero. Entre la fauna acuática se pueden citar el pintado, el jaú, el dorado,  el armado,  el surubí y el  pacú. Entre la avifauna se destacan el jabirú, el tataupá, el muitú, la espátula rosada y el jacana común.

Turismo
El parque está abierto al público en forma gratuita todos los días de la semana. Posee varios espacios dedicados al ocio y al ecoturismo así como varias playas sobre las costas del Paraná.
En la isla se encuentran también varios yacimientos arqueológicos pertenecientes a los indios guaraníes  y  xetás.

Ilha Grande
Áreas protegidas del estado de Paraná
Áreas protegidas del estado de Mato Grosso del Sur
Ilha Grande
Sitios relevantes para la observación de aves en Brasil
Áreas protegidas establecidas en 1997
Brasil en 1997

redpajama_set_name: RedPajamaWikipedia


Within the first place, if you wish to understand the way to make beta bucks in Diablo 3 successfully, you usually have to investigate the market state of affairs. Beta is actually a platform for you to elaborate the gear by your self and make your means by way of Diablo three and check the auction home because you own free foreign money. Just lately, the marker is prevalent with craftable and low-cost objects. The really good objects are very costly. When making use of the market, the first thing to do is to ponder over the costs of the supplies. The material costs for common flotsam and subtle essence in Diablo three are one beta buck each. The fallen tooth is value of looking at cause it is worth 1.5 beta bucks to around eight beta bucks. The one one material that can be created is the yellow craftable item known as handed crossbow for the demon hunters.
Television commercials are made with the sport-successful three, but NBA Championships and legends are made via proving that no one can cease you. And when Lebron places his head down and goes to the basket, there is not a player in this league that may stand in his method.
Here is tips on how to go to your neighbor's zoo: What has modified: So do you need a Diablo three information? Need help discovering the perfect online online game design program? Discover some ideas to help you find the proper video game design faculty online.
Speaking to a Runescape seller provides you the chance to spice up your confidence in communicating with the proprietor of the website. Rule Quantity 2 After you've gotten talked to the vendor, the subsequent rule is to learn the phrases and conditions properly. By learning the terms and circumstances, you will be able to know the nature of what you might be shopping for and utilizing. Be sure to have a assured Runescape Gold guide. Is there any type of coverage for refunds? Pay attention to those sites that provide ensures so long as ninety days.


Once upon a time in the Land of Magic and Enchantment lived a young man named Zyll who dreamed of becoming a Master of Black Magic. Fortunately, all Zyll could do was fail - his potions never perked, the spells seldom worked. Still, Zyll was determined to practice the dark magic and promised to one day take over as Ruler of the Realm. The people banished Zyll from the land for his evil plans.
One day after spoiling his latest potion, Zyll hurled the flask to the ground. He watched in amazement as smoke billowed and a black orb appeared before him, suspended in air. Cautiously approaching the sphere, Zyll felt a surge of energy race through his body. This was the mystical Black Orb his ancient books of magic had described! It was written that whoever possessed the orb would have magical powers greater than any other sorcerer.
Using his new powers, Zyll took revenge against the land. He stole the magnificent Great Treasures that had been hidden in secret vaults for years and used the Black Orb to turn the once beautiful and wealthy country into a barren wasteland.
You, daring adventurer, decide to challenge the powers of Zyll. Magically, you are transported to a place near the Castle Mitain, Zyll's home. You must capture the mystical Black Orb and carry it home with you to restore the countryside to its former beauty. There is only one way to return home - the instant that four or more of the Great Treasures are brought together, you will be transported back to the Land of Magic and Enchantment.
Each time you play Zyll, many objects are randomly placed throughout the game. By pressing the Esc key while the music plays at the beginning of the program, you can cause those objects to appear in the same place each time. This is a good way to learn the game or challenge your friends in tournament-style play since the objects will be in the same spots for each tournament player.


support children as they develop confidence in their ability to use science to understand and positively impact the world.
Who lives in the Cary forest, and what are they up to? This summer our Eco-Discovery campers will study the forest ecosystem from the ground up and will get to know the plants, animals, and microbes that keep the forest ticking.
Campers can look forward to hiking, exploring, asking scientific questions, and playing plenty of games in the woods. We hope that by the end of the week they'll have a healthy curiosity about forest ecology and a desire to serve as forest stewards for the future!
How do campers spend their week?
At the Cary Institute's Ecology Camp, children have a unique opportunity to experience ecological science with our skilled ecology educators and research scientists. During Eco-Discovery Camp, children entering grades 2-7 explore the hills, valleys, ponds, and streams of our 2,000-acre Dutchess County campus. Throughout each 1-week session campers conduct scientific investigations, learn about the natural history of the area, and participate in team building activities.
Each year the camp has a different theme, allowing our many returning campers to have unique experiences year after year. Past camp themes have included: Decomposition (2014), Stream Pollution (2015), Nature's Structures (2016), and Bugs, Bacteria and Beyond (2017), and "What's In Our Water?" (2018).
Visit the camp Flickr photo gallery to see just how much fun our campers have!
Each week of camp will have a approximately 12 campers and will be dedicated to either younger campers (entering grades 2-4) or older campers (entering grades 5-7).
Two educators with extensive experience in ecology and education will teach each week. We're also fortunate to have a high school-aged Eco-Leader volunteer helping with camp each week.
Eco-Discovery Camp for 2nd -4th graders runs from 9am to 3pm, Monday through Friday, with a late pick up (4pm) option available. For 5th – 7th graders, the camp day runs from 9am to 4pm. This year, the first week is a pro-rated four day session due to the July 4 holiday.
Can campers attend multiple sessions in one summer?
Unfortunately, demand is so high that we are only able to invite each camper to attend for one session per summer. In addition, each week of camp follows the same curriculum, and therefore campers may participate for one session only. We typically fill each session to capacity, so be sure to reserve your preferred week early. However, middle school students are invited to participate in both our Eco-Discovery camp and our Art + Science course.
Our one week sessions cost $260 and $300 for younger and older campers, respectively. Session 1 is pro-rated to $210 because camp will be closed on July 4.
Late pick-up for younger campers (4pm) – add $50/week.
Withdrawal from camp prior to June 7, 2019 refunded total fee less $25.00 for administrative costs. No refund for any reason after June 7, 2019.
Through the generosity of community members and the Dyson Foundation, we are proud to offer a limited number of scholarships to families who could not normally afford to send their children to camp. Scholarship recipients attend camp for a nominal registration fee of $20.
To be eligible for a scholarship students must qualify for free or reduced lunch, as outlined by federal income eligibility guidelines. While we encourage all eligible students to apply, this year we are especially interested in supporting students from English Language Learner families. We can provide most pre-camp materials in Spanish upon request. Scholarships are awarded on a first come, first served basis. Typically all scholarships are awarded by the end of April, so please apply early.
Please return the application form to Shelly Forster via email (forsterm@caryinstitute.org) or mail (2801 Sharon Turnpike, PO Box AB, Millbrook, NY 12545).
Our Eco-Leaders Program is for students entering grades 8-12. Each Eco-Leader assists educators during one Eco-Discovery camp session while also leading their own activity and assisting in data collection. This is similar to a junior counselor program, and includes a required training session prior to camp. Eco-Leaders must apply to the program by March 15, 2019.
Middle and high school students are invited to participate in our weeklong Art + Science program. Students will spend one to two weeks exploring Cary's field, forests, and streams through the art of scientific observation and will create a beautiful field book of ecological discoveries.
For more information about the Cary Institute's Ecology Camp, contact Shelly Forster at (845) 677-7600 ext. 303 or via email at forsterm@caryinstitute.org.


Are you bothered by the skin discoloration on your face? You can once again enjoy a bright and even complexion with a few simple steps.
This video explains why dark spots develop and what you can do to prevent and alleviate them. Though discoloration can sometimes appear because of acne and other skin conditions, it often presents due to excessive sun exposure. UVA and UVB rays can damage skin tissues and cause dark spots. So the best way to avoid an uneven complexion is to protect yourself from the sun with sunscreen, sunglasses, and hats. If you already have dark spots, talk to a skin expert about the services and products that can reduce their appearance.
Blackhawk Plastic Surgery offers laser resurfacing to correct facial dark spots. For more information, call our Danville office at (925) 272-2464.


text:
// @flow

/**
 * Downloads a JSON object.
 *
 * @param {Object} json - The JSON object to download.
 * @param {string} filename - The filename to give to the downloaded file.
 * @returns {void}
 */
export function downloadJSON(json: Object, filename: string) {
    const data = encodeURIComponent(JSON.stringify(json, null, '  '));

    const elem = document.createElement('a');

    elem.download = filename;
    elem.href = `data:application/json;charset=utf-8,\n${data}`;
    elem.dataset.downloadurl = [ 'text/json', elem.download, elem.href ].join(':');
    elem.dispatchEvent(new MouseEvent('click', {
        view: window,
        bubbles: true,
        cancelable: false
    }));
}

redpajama_set_name: RedPajamaGithub


text:
Serving the Principia Community by Fostering Honest Discussion
ROLM phones roll out
By: Will Pappas Posted on May 4, 2012 December 26, 2014
The number 23 is significant for a few reasons. Michael Jordan wore jersey number 23, Julius Caesar was stabbed 23 times, and there's even a movie titled 23. The most relevant fact about the number 23 to the Principia community is that it's the number of years the current Principia phone system – scheduled to be changed next year – has been in place.
"What's that you say? An upgrade?" Yes, it's safe to say that our archaic phone system is in need of replacement. Richard Booth, Chief Technology Officer of both Principia campuses, has been working on establishing a new system at Principia for some time now. Booth said the outdated phones are becoming more difficult to repair as the system falls out of use. He explained: "We're at risk of having a part breaking [in the current system], and not being able to replace the part, and in essence, not having part or all of a phone system if that were to happen." According to Booth, the current phone set-up is not sustainable – the original manufacturer no longer exists. "It feels like the room phone is kind of past its prime. It's no longer where the action is for anybody and . . . mobility is what's driving all of us," said Booth.
The current phone system is scheduled to change over in December 2012 to a "mobility integration" system. Booth explained that whether you are a student, faculty or staff member, a wide range of devices will be able to be used to make calls with the extension given to each member of the Principia community. Devices such as basic phones, smart phones, iPod touches, iPads, and computers can all be integrated to send and receive phone calls via one's extension. "[The devices] can be used to act like a system phone in many ways," said Booth.
By December, the current phones will be taken out of all rooms and will not be replaced. The phone network of Principia will be run completely wirelessly through personal devices. For those who lack this technology, Booth recommended an upgrade. Since over 98 percent of Principia students at least own a personal computer, there is a very small percentage of people that will have to look into buying a device that can be used to support their Principia phone extension.
The application for this integration is called Jabber. Whether one is on a smart-phone, computer, or Wi-Fi device, he or she will be making and receiving calls through Jabber. According to Booth, the Jabber app looks very similar to the phone app on a smart phone, the only difference is that the Jabber user is limited to calls within the Principia system. Furthermore, according to Zach Retzlaff, the Telecom Director, faculty, staff, and students will be able to use the Jabber app off-campus to make and receive calls using the 4-digit Principia extension. All that's needed is a WiFi hotspot or a cell carrier's data network. Christian Richardson, Student Body President and CIS representative for Student Senate, said, "It's a much more direct way of communication." With the system gone mobile, students no longer need to be in their rooms to receive a call. They can be anywhere on or off-campus and if their 4-digit extension is dialed, they will receive the call. The new system allows everyone to be more accessible and available, and the ability to reach someone will be even easier.
Richardson worked with Richard Booth in seeking student input about the desired look of the future system. This input was taken into consideration when discussing and implementing the new phone system for next year.
One of the most appreciated features of the new system could very well be the larger storage space allotted for voicemail. The current system allows a maximum of 10 messages to be stored collectively between new and saved messages. Although storage won't be unlimited on the new phone system, Retzlaff assured us that "there will be a lot more storage available for a lot less cost to maintain it." Users also will have the option to have voicemails sent to their e-mail, which will include a sound file attachment of their message. This will allow for unlimited storage of voicemail messages.
Categories: News, Student Life
Meet Your New Senate
Meeting the Middle East…at Stanford
Subscribe to Pilot Online via Email
Enter your email address to subscribe to The Pilot online and receive notifications of new posts by email.
Copyright © 2021 All Rights Reserved | Magpaper by Theme Palace


Became One of the Fastest Growing Companies with Transition from Sales Team-Based to Marketing-Focused Corporation, That Included Implementation of a Key Marketing Executive Role and Several Other Executive Placements.
Achievers created an industry-leading employee engagement platform based on rewards and feedback. Adoption of their platform was growing and they needed to change their business model, which was why they engaged us as their recruitment partners.
When we began working with Achievers, the company was known as I Love Rewards. They had just landed $8.9M in funding to propel their transition to a marketing-driven model.
Shifting from a sales-team driven organization to employing a marketing-based approach is a complex task. They needed a Senior Marketing Executive with specific experience and qualifications that was capable of overseeing the move.The candidate needed an extensive strategic digital marketing background and would be expected to implement Eloqua and Salesforce. It was crucial that the Senior Marketing Manager role be filled by an individual capable of managing and overseeing the changeover on-the-fly.
The candidate we identified was on the market because his strategic marketing efforts had driven revenue growth to the point where his company was acquired for over $200M. We made the introduction and Achievers made an offer.
Named Fastest Growing Company at the American Business Awards.


In four simple steps, you can enroll in our Voice Print System. In a matter of minutes, the entire process can be completed and you'll enjoy the peace of mind that comes with enhanced security.
When prompted, say "I'm not enrolled." An Investment Representative will verify your identity, explain the simple enrollment process and answer any questions you might have. You will then be connected to the automated enrollment system.
Create your unique client identifier.
You will be asked to select a 10-digit telephone number – the phone number that you will most easily remember. This will serve as your primary phone number and unique client identifier. When prompted by the enrollment system, say this primary phone number.
Say your voice verification phrase.
When prompted, say the short verification phrase, "my voice is my password."
Record your secret date and hint.
When prompted, record your secret date which only includes a month and day. For example, June 10th. It should be easy to recall, but hard for others to guess, like a special anniversary or a friend's birthday. After the date is spoken, you will then be asked for a hint as a reminder. Remember to keep this information secure and do not share it with others.
Congratulations! You are now enrolled in the Voice Print System.
From now on, when you call us and say your primary phone number and secret date, your voice will be used to confirm your identity. You will then be connected with an Investment Representative to assist you with your transactions.
If you wish to make changes to your Voice Print, simply call 1-800-465-5463 and an Investment Representative will assist you.
For more information, or to enroll, call 1-800-465-5463.


 OUTREACH--IT'S IN OUR NAME!
Stokesdale Church of God is a ministry involved in going outside of the four walls of the church into the communities of the Triad areas. We offer free food, new clothes, new toiletries, and encouragement to area neighborhoods. We share the love of Christ without criticism or judgement to the lost and hurting souls of our brothers and sisters.
S.C.O.G. offers a unique worship experience for all! We minister to "the whole man" in order for "man to be made whole" again.
The SCOG Van Ministry picks up those desiring to attend services.
It's almost that time! Check back for dates and times.
SCOG is at the Bethesda Center!
and the love of God in our community!


text:
Bobby Valentine Tells Boomer & Gio Donald Trump Photo Sunk Him
PGA Tour Expects Mic'd Players To Be Common For 2023 TV Broadcasts
"Valentine ran as an unaffiliated candidate and fell to Democratic State Rep. Caroline Simmons in the Stamford mayoral race."
Russ Heltman
Courtesy: WFAN
Former MLB manager and ESPN baseball analyst Bobby Valentine joined WFAN's Boomer and Gio this week to discuss his mayoral campaign in Stamford, Connecticut.
Valentine ran as an unaffiliated candidate and fell to Democratic State Rep. Caroline Simmons in the race. He claims that a decades-old picture with him and former President Donald Trump sunk his chances.
Boomer & Gio with Bobby Valentine pic.twitter.com/5juCTrtxr9
— Morning Show with Boomer & Gio (@WFANmornings) November 16, 2021
"We had a photo taken together in 2000 for the World Series and so the last day of the campaign all around the neighborhoods, a picture of Donald and Bobby with the quote 'only poor people and dumb people pay taxes,'" Valentine told Boomer and Gio about the photo that circulated around the town on Election Day.
"That really helped with the minority vote in my town," Valentine said sarcastically.
It wasn't all bad news for Valentine, who was enamored with the campaign-building process, among other things.
"Built it [the campaign] from scratch, which was a wonderful experience" Valentine explained. "Figuring out how to get volunteers together, and money together, and office, and headquarters together. We actually ran a six-month—perfectly clean—campaign. Not one negative word mentioned the entire time. Got 14,000 votes, more than any non-Democrat ever got in our city, and almost won that thing.
"I'm glad that I was the candidate, and I'm also glad that I'm not the mayor because it's really a tough job. I got four years of my life back when the votes came in."
Valentine worked at ESPN for a few years in the early part of the 2010s before re-entering the managing circuit with the Boston Red Sox. He famously managed the Mets to one of their two World Series appearances this century in 2000.
"It's a little bit of the seven-year itch," Valentine said when asked why he's always looking for the next obstacle. "I did seven years in Texas; seven years in New York; seven years in Japan; seven months in Boston. Then I did seven years at Sacred Heart. So, yeah, it's all about the sevens."
Russ Heltman is a daily news writer for BSM. He is the morning host and producer for 89.3 WMKV in Cincinnati, OH. He also works in gameday communications for FC Cincinnati and additionally contributes to the AllBengals blog for Sports Illustrated. Russ can be found on Twitter @RussHeltman11 or you can reach him by email at Heltmandm@yahoo.com.
Related Topics:Barrett Sports MediaBobby ValentineBoomer and GioBoomer EsiasonBoston Red SoxBSMESPNGregg GionnattiJason BarrettSports Media NewsSports Radio NewsStamford Mayoral RaceSunday Night BaseballWFAN
Michael Irvin Tells Parkins & Spiegel How He Learned What Guacamole Was
Tony Rizzo To Baker Mayfield Critics: I Hope You're Happy
Does Mike & The Mad Dog Reunion Really Have Broad Appeal?
Jamie Erdahl Reflects On First Season of Good Morning Football
"The Cowboys in the Super Bowl against the Chiefs would've shattered all viewership ratings."
The matchup in this year's Super Bowl is set, and the game will undoubtedly be the most-viewed program on TV this year. But if the Dallas Cowboys were taking part in the game, it's safe to say the ratings would be astronomical.
The Cowboys divisional playoff game against San Francisco drew 45.7 million viewers. It was the second-most watched divisional round contest on record.
The NFC championship between San Francisco and Philadelphia drew 47.5 million.
On 105.3 The Fan in Dallas, K&C Masterpiece host Kevin Hageland said had the Cowboys made it to Philly, the viewership would've been even better.
"I know the game sucked, but that just shows you, because the Cowboys were like almost 8 million above every other divisional game, this could've gotten to 58 (million)," Hageland said.
Kevin added that if Dallas had gone all the way, the audience tuning in would've easily eclipsed some of the highest-rated programs of all-time.
"The Cowboys in the Super Bowl against the Chiefs would've shattered all viewership ratings," he said. "Even with the new system and so many people streaming and everything like that."
Usually the Super Bowl averages around 100 million viewers. Hageland said a Cowboys Super Bowl appearance in this day and age would've set the new top ratings mark for years to come.
"My estimation would be you would add approximately an extra 30 million people," he said.
Jordan Bondurant is a features reporter for Barrett Sports Media. He works full-time as a multimedia specialist at the Virginia State Corporation Commission, while also putting in part-time work for News Radio WRVA and 910 The Fan in Richmond. Additionally, you can find Jordan contributing coverage of the Washington Capitals for the blog NoVa Caps. His prior media experiences include working for the Richmond Times-Dispatch, the Danville Register & Bee, Virginia Lawyers Weekly and ABC 8News. He can be reached by email at jordan.e.bondurant@gmail.com or follow him on Twitter @J__Bondurant.
BSM Writers1 day ago


Product prices and availability are accurate as of 2019-04-20 07:21:55 BST and are subject to change. Any price and availability information displayed on http://www.amazon.co.uk/ at the time of purchase will apply to the purchase of this product.
We are happy to present the brilliant NGT Carp Fishing Set Green Insulated Carryall 3+3 Made Up Rod & Reels Holdall.
With so many available right now, it is great to have a name you can trust. The NGT Carp Fishing Set Green Insulated Carryall 3+3 Made Up Rod & Reels Holdall is certainly that and will be a superb purchase.
For this reduced price, the NGT Carp Fishing Set Green Insulated Carryall 3+3 Made Up Rod & Reels Holdall comes highly recommended and is always a regular choice amongst lots of people. NGT have included some excellent touches and this equals great value for money.


text:
Q: Carregar todos as dependências dinamicamente No ficheiro index.php faço o include de todos os controllers:
<script src="app/app.js"></script>
<script src="app/ctrl_A.js"></script>
<script src="app/ctrl_B.js"></script>
<script src="app/ctrl_C.js"></script>
//etc...

Isso não é bom, uma vez que estou a carregar ficheiros javascript que não fazem falta, por exemplo, na homepage.
No .config da app estou a fazer referência ao controller da seguinte forma:
app.config(['$urlRouterProvider', '$stateProvider', '$locationProvider',
function($urlRouterProvider, $stateProvider, $locationProvider) {
    $urlRouterProvider.otherwise("/login");
      $stateProvider
        .state('login', {
            url: "/login",
            templateUrl: "view/login.html",
            controller: 'ctrl_A'
        })
//...

Como faço para que as dependências (controller, factory, directive, ect...) sejam carregadas dinamicamente sem declarar no index.php?

A: Acredito que a melhor forma seja usar o angularAMD. Ele basicamente une o AngularJS com uma definição de carregamento assíncrono de módulos Javascript chamada AMD, que faz justamente o que você espera.
Seu index ficaria apenas com um script desta forma:
<script data-main="app/app.js" src="app/libs/require.js"></script>

Transformar o seu código em módulos AMD traz benefícios a manutenibilidade do seu projeto não é uma tarefa difícil.

redpajama_set_name: RedPajamaStackExchange


Air freight is known to be the best transport alternative for high-value and low-volume shipments. But are there any other reasons for using air freight? Sure there are. In this blog post, I share the top 6 benefits of air freight.
In this blog post, I share some of the essential facts about the new IMO regulation, how it will affect ship operations, and protect marine life.
Driverless vehicles beaming through the air and capsules transporting goods in the blink of an eye. Sounds like a sci-fi movie? The truth is, the future is not very far away.
In honour of the International Women's Day, we want you to meet three of our many amazing women at Greencarrier. They have green logistics and solutions in mind every day at work. Get to know Christina, Åsa and Minna!
Derived from shared values and engagement, Greencarrier Freight Services helped Haglöfs with two main challenges. The result?
The growth of E-commerce, digitalisation of supply chains and the development of automation technologies bring great potential to the container shipping industry now and in the future.


text:
Cololabis is a genus of sauries found in the eastern and northern Pacific Ocean.  The name is derived from the Greek word kolos, meaning "short", and the Latin word labis, meaning "forceps", referring to the short beak of the type species Scombresox brevirostris.

Species
There are currently two recognized species in this genus:
 Cololabis adocetus J. E. Böhlke, 1951 (Saury)
 Cololabis saira Brevoort, 1856 (Pacific saury)

References

Scomberesocidae
Taxa named by Theodore Gill
Marine fish genera


text:
Q: Firefox always show development tools Is there a way to always show developer tools when opening a new tab in Firefox?
In the past I always used Firebug, where I used to just detach a window, and it just automatically targetted whichever tab I was on.
However since it's now discontinued, I'm using Firefox's built in developer tools and am having an issue where every time I open a tab, I have to manually enable developer tools, then refresh the page every time.
This is fine most of the time (if not a little inconvenient), however if you are posting data, the extra refresh of the page can cause duplicate submission problems etc.


Starting for 1 January 2018, the Government has introduced Value Added Tax (VAT) at a standard rate of 5% applicable to most goods and services in the UAE. VAT registration is a process of listing the business with the Government. Once a business is registered, it will become eligible for the return of VAT. Businesses will get VAT registration in the form of a VAT certificate containing a unique Tax Registration Number (TRN). This number will be essential for all the tasks to be carried out for VAT in UAE.
A business must register for VAT if their taxable supplies and imports exceed the mandatory registration threshold of AED 375,000 and may choose to register for VAT voluntarily if their supplies and imports are less than the mandatory registration threshold, but exceed the voluntary registration threshold of AED 187,500.
In order to register for VAT, knowledge of tax legislation and procedures is required. Without it, registration application can be interrogated or rejected which will significantly delay business operations. Therefore, many businesses outsource this task to specialists who can assist entire registration and compliance process.
Our firm provides a simple, personalized and cost-effective service. Business entities will not be required any deep knowledge of VAT laws and can benefit from our VAT expert team to obtain the VAT number and other registrations as quickly as possible.
The process of registration is done online. After online VAT registration, business entities will get Tax Registration Number (TRN) from Federal Tax Authorities (FTA) within the duration of 2-3 weeks. Further, to get the hard copy of the tax certificate, business entities will pay an amount of AED 500 and FTA will deliver the certificate by courier to the given address.
Does owner have any other entities?
Is the business is engaged in import and export?
We would be delighted to discuss how we can help you, and your group or company. Please get in touch and contact us at [email protected] or alternatively, contact our office directly.


All Center for Exposures, Diseases, Genomics, and Environment (EDGE) investigators are organized into Collaborative Research Teams (CRTs) around thematic, environmental disease-focused topics. Many of our investigators work across two or more of these, but still identify primarily with their designated CRT. See the EDGE Member Directory for details on CRT affiliation.


text:
Bible Verses Like 2 Kings 5:9
"So Naaman came with his horses and with his chariot, and stood at the door of the house of Elisha."
Bible verses related to 2 Kings 5:9 (similar cross-references)
2 Kings 3:12 - And Jehoshaphat said, The word of the LORD is with him. So the king of Israel and Jehoshaphat and the king of Edom went down to him. (Verses like 2 Kings 3:12)
2 Kings 6:32 - But Elisha sat in his house, and the elders sat with him; and the king sent a man from before him: but ere the messenger came to him, he said to the elders, See ye how this son of a murderer hath sent to take away mine head? look, when the messenger cometh, shut the door, and hold him fast at the door: is not the sound of his master's feet behind him? (Verses like 2 Kings 6:32)
Isaiah 60:14 - The sons also of them that afflicted thee shall come bending unto thee; and all they that despised thee shall bow themselves down at the soles of thy feet; and they shall call thee, The city of the LORD, The Zion of the Holy One of Israel. (Verses like Isaiah 60:14)
Acts 16:29-30 - Then he called for a light, and sprang in, and came trembling, and fell down before Paul and Silas,And brought them out, and said, Sirs, what must I do to be saved? (Verses like Acts 16:29)
Acts 16:37-39 - But Paul said unto them, They have beaten us openly uncondemned, being Romans, and have cast us into prison; and now do they thrust us out privily? nay verily; but let them come themselves and fetch us out.And the serjeants told these words unto the magistrates: and they feared, when they heard that they were Romans.And they came and besought them, and brought them out, and desired them to depart out of the city. (Verses like Acts 16:37)


These Aqua Rose Big Borders are 2" long and 1/2" wide, and there are 25 in this package.
Aqua Rose is a four color art glass with clear being one of the color components. One side is slightly textured, the other side is smooth. Often the most intense coloration is on the smooth side. Using both sides of the mosaic tile can create depth and definitely allows you to produce a truly unique piece of mosaic art.


Pray for the students now on Winter Break who will return for classes at the end of July.
Pray for the intensive course being offering the second week of July in Pretoria.
Pray for the ongoing accreditation maintenance and upgrades with the South African educational agencies.
Pray for extra full-time lecturers needed to teach next year in KwaMhlanga and Johannesburg.
Pray the Lord will continue to strengthen the entire Mukhanyo organization as the ministry continues to expand.
Give thanks for the consistent financial support and pray the Lord will continue to provide suitable donations.
Give thanks for good governance by the Board of Directors and pray for management team of the college.


Evans is evaluated as my most unique Personal Portfolio HTML template with clean and modern design. Evans will be a subtle and smart choice for Creative Person like Web Developer ,Web Designer, Graphic Designer. There is no doubt that Evans will make your work look more impressive and attractive to viewers.
This template includes 08 carefully designed HTML pages, which are easy to edit and customize to fit your needs. Template is perfect solutions for the create of unique web projects.


This section includes information on the development of Domestic Violence policy and practice nationally and locally.
The key milestones in the development of specialist services and best practice in Nottingham have progressed alongside national developments. However Nottingham has also at times developed ahead of national improvements in provision and practice.


Prevention First celebrates the positive influence of parents in the lives of their kids and makes the following suggestions to help you start off a meaningful and important discussion in 2011 with your family!
1. Teach your children to trust you by seeing you as a role model.
2. Be patient, not just tolerant. Apologize when you make a mistake or do something you regret.
3. Ask teens what they need from you.
4. Listen to your teens, a lot.
5. Teach your children about ethics, values and principles they can apply in choices and decision making.
6. Help them discover the feeling of gratitude.
7. Keep the promises you make. If you do not keep your word, acknowledge that. Help your teen understand the circumstances or choices that precipitated the change in your plans.
8. Answer your teen's questions and be consistent. When you notice behavioral changes in them, make yourself available and encourage them to talk about what is going on in their life.
9. Be understanding when they have a difficult time and let them know you will love them no matter what.
10. Be diligent. Have ongoing conversations with your kids about the risks of drugs and alcohol.
For the coming New Year, resolve to talk more often with your family about healthy decisions and choices! Research shows that youth who learn about the dangers of drugs from their parents are up to 50 percent less likely to use than those who do not get those important messages at home. For more information please contact us at www.PreventionFirst.net or call our Resource Center at 732.663.1800 ext. 216.