Shoe Trees are inserts of any shape that keep your shoes in amazing shape as they age. This means that even crunched up newspaper or old cardboard stuffed into shoes technically qualify as 'Shoe Trees'.
That said, quality shoe trees made of raw cedarwood and shaped like feet has a plethora of additional benefits: absorbing moisture, preventing lining rot, freshening the interior, and preventing creases and cracks more effectively. This drastically extends the life of your shoe – especially important if you have splurged on them!
Why do I need shoe trees?
Although pricey, fine footwear is capable of lasting literally a lifetime and maybe more – but you'll have to take care of it. Quality Shoe Trees are an investment, much like a durable Spigen phone case for your new iPhone! A good pair of shoes cost between $300 – $1500, excluding bespoke shoes, whereas a pair of shoe trees only costs $35 – an insignificant amount when considering that they extend the average lifespan of the leather upper from 3 years to 30 years. That is 1000% more value for about 3.8% more that you pay. No wonder the highest-end shoes come with shoe trees, retailers cannot risk them spoiling before sale!
Shoe Trees work a lot like hangers, keeping your shoes in shape and preventing creases. If you do not store your best shirts without a hanger, why would you store your shoes without Shoe Trees?
At the microscopic level, leather is made up of a tangle of fibers held together with protein bonds. Fats and oils keep the protein bonds from breaking.
When water (from your sweat or from the rain) penetrates into leather, it forms temporary bonds with the oils that bond the leather fibers then floats them to the surface as it evaporates. The leather fibres become brittle and cracks when flexed.
Quality Shoe Trees made from cedar wood is porous and absorbs moisture before it can penetrate the leather, maintaining the strength of your leather for decades!
Cause smelly feet and feet infections, including athletes foot.
The absorbent properties of Shoe Trees destroy that moist environment and inhibits bacterial and fungal growth. In addition, aromatic wood species like cedar emit an invigorating scent that also freshens your shoe!
When should I use shoe trees?
You should insert shoe trees everyday immediately after taking off your shoes, when the leather is wettest from a whole day of sweating. This helps remove moisture before it can penetrate into the leather. By unfurling the sole and filling out the leather upper as the shoe dries, it makes sure the shoe dries into the proper shape without creases. There is no need to bring along shoe trees when visiting your relatives, but once you reach home, the shoe trees should be in for a night's of work.
Whether you were caught in the rain, or you had something spilled onto your precious footwear, you should dry it up with some newspaper, then get a pair of unfinished (without any coating) cedar shoe trees into your shoes sooner rather than later to wick all that moisture out. This will minimize the loss of essential oils from the leather due to water, keeping it strong and supple.
How should I use shoe trees?
Holding the knob, push the head of the shoe tree in until the Twin-tube compresses and fit the heel in.
If the Shoe Trees do not fit on maximum compression, they are too large. If they rattle around when fully extended, they are too small. At The ShoeTree Project, you get a FREE Size Exchange in these cases!
Spring shoe trees probably shouldn't qualify as Shoe Trees at all. These mass produced objects not only do not keep your shoes in shape, they run a high risk of distorting them.
The head of these shoe trees are inserted and the tail is bent and lodged into the heel of the shoe. Because the tail is so narrow instead of being shaped like a heel, it places excessive pressure on one point of the shoe and overstretches the shoe away from the shape of a regular human foot.
They are mass produced in one size only, so the spring has to be extra long, meaning that they nearly always place too much pressure across the shoe, unless you have monster-sized feet.
Full-toe Shoe Trees usually have a spring mechanism along its length, which helps to unfurl the sole and prevent some creases. However, the head is a simple solid block and does not fill out the toebox. Full-toe Shoe Trees are also less versatile, unable to accomodate a large range of shoe shapes. It's generic head shape does not imitate your feet well, so it may not dry your shoe in the ideal shape. This is a cost-friendly option for cheaper shoes, though the absolute savings are only about $10 from a proper Split-toe pair.
Combination Shoe Trees combine the Split-toe and Full-toe designs into one for a (marginally) cheaper option to the Split-toe. The Combination Shoe Tree is able to both extend to unfurl the sole, and expand sideways to fill the toebox. Like the Full-toe Shoe Trees however, they utilise a generic head that is easy to mass produce. Hence the expansion may deform the front of your shoes away from the shape of your feet.
Split-toe Shoe Trees are a 3-part Shoe Tree (aka Epic Shoe Trees) that have been engineered to closely approximate the shape of your feet, instead of using a generic symmetrical head like the Full-toe and Combination Shoe Trees.
Split-toe Shoe Trees usually employ two spring mechanisms that exert biplanar (along the shoe and across the toebox) pressure, imitating the pressure of your feet against the shoe upper. The spring-loaded Twin tubes push a fully crafted heel and ergonomic head to unfurl your sole with even, distributed pressure, while the Split-toe (also spring loaded) stretches out the vamp of your shoe. Together, they work to keep your shoe in the correct shape and prevent creases without distorting the shape of your shoe.
Because of the width of the head can be varied, Split-toe Shoe Trees can fit a very wide range of shoe shapes, and provide the next best fit after lasted shoe trees – for a tiny fraction of the cost.
Lasted Shoe Trees are copied from the shoe last – the mold upon which a shoe is constructed, which determines the shoe's size and shape. This means that a lasted shoe tree will fit your shoe perfectly, but only on that pair it was built for. Lasted Shoe Trees are able to keep your shoe in its original shape without the Split-toe mechanism as all the dimensions have been made to measure.
You can get lasted Shoe Trees from your shoemaker. However, they are quite pricey costing upwards of $100 as they have to be made specially for you. Are they essential or practical? Not really, but neither is putting in custom interiors into your Ferrari. You do it because it looks good, and completes the purchase. You could live with the stock interior or the cheaper shoe trees. It won't deteriorate the product, only make it less attractive. If you do get the >$5000 bespoke shoes that are made exactly to the shape of your feet though, lasted shoe trees in the shape of your feet will likely be included for free.
Plastic Shoe Trees are light, cheap, and easy to produce by the thousands via injection molding. They do help to keep your shoe in shape. However, they do not have the absorbent properties of wood to wick moisture from the leather linings, and may even inhibit its drying by reducing contact with air. This leads to all sorts of problems in the long run, including lining rot, cracked leather, and really smelly shoes.
Getting plastic shoe trees for its price is like pumping unleaded fuel into your Lamborghini – saving a few dollars and spoiling thousands.
These are Shoe Trees made from wood, but finished with a layer of varnish to make them shiny and more elegant. However, they are also water proof, meaning that they are essentially a more expensive, heavier, and more aesthetic version of plastic Shoe Trees. Hence, they will also pose the same problems as plastic imitations, namely lining rot, cracked leather, and smelly shoes.
Usually, these Shoe Trees utilize lower quality sapwood (instead of heartwood) that are not resistant to decay, hence the need for a protective layer. Sapwood is also structurally weaker.
Unfinished (or raw) Cedarwood is the prime option for a pair of Shoe Trees. Without any external coating, Shoe Trees made from this porous material are able to absorb moisture and prevent lining rot.
Cedar wood absorbs the odour of your feet and replaces it with its signature crisp, tangy fragrance. You'll look forward to wearing your shoes and never fear taking them off in public again.
If your cedar Shoe Tree is made from heartwood (wood from the center of the trunk), it will be resistant to fungal decay.
The aroma of cedar not only freshens your shoe interior, it also repels insects. The last thing you need is to insert your feet into your shoe for a nasty bite from a nesting creeper!
The decay-resistant properties and durable structural makeup mean that cedar Shoe Trees last literally a lifetime.
This is true even for its unique fragrance – as soon as it weakens, simply sand the Shoe Tree lightly with sandpaper* and the aroma will return strong as ever!
The ShoeTree Project only uses the most durable, unfinished heartwood from the Juniperus Virginiana (American Red Cedar), which is the most fragrant species of cedar. You differentiate this premium material from its distinct reddish-pink hue with white strips.
Beech and Schima Superba wood are alternatives to cedar and cost around the same as well. They are usually in a yellowish-white colour, which some people may prefer for its looks.
Beech and Superba are less capable than cedar at wicking moisture from your leather interior, with Superba being slightly less effective than Beech. Both Beech and Superba do not have any natural fragrances, and therefore do not provide a freshening effect for your shoe interior.


text:
Bagnoli ist der 18. von den 30 Stadtteilen (Quartieri) der süditalienischen Hafenstadt Neapel. Er liegt am Meer in der Bucht von Pozzuoli und gehört zur westlichen Peripherie Neapels.

Geographie und Demographie
Bagnoli ist 7,96 Quadratkilometer groß und hatte im Jahr 2009 23.648 Einwohner.

Geschichte

Der Name Bagnoli leitet sich wahrscheinlich vom altgriechischen Wort Balneolis ab, da es bis zur Ansiedlung der Stahlindustrie mehrere Thermalbäder gab.

Zu Beginn des zwanzigsten Jahrhunderts fasste in Bagnoli erstmals die Stahlindustrie Fuß, wodurch sich der Ort nachhaltig industrialisierte. Zu jener Zeit errichtete die Società Anonima Ilva, aus der später der Konzern Italsider wurde, ein Stahlwerk mit einer Kapazität von schließlich 2,3 Mio. t. Zwei Hochöfen wurden Ende der sechziger Jahre neu installiert. Aufgrund von politischen Konflikten wurde der Bau eines Warmwalzwerks unterbrochen. Das Werk arbeitete in den 1970er Jahren und vermutlich auch später stark defizitär. 1991 wurde das Werk aufgrund der Stahlkrise geschlossen.
Bis 2005 wurde es abgerissen.

2016 versuchte der damalige italienische Ministerpräsident Matteo Renzi, das Areal zu sanieren und neue Firmen anzusiedeln.

In den Jahren von 1946 bis 1951 bestand ein Flüchtlingslager der Internationalen Flüchtlingsorganisation. Im Rahmen der Operation Keelhaul haben die Alliierten von dort in den Nachkriegsjahren tatsächliche oder ehemalige Sowjetbürger zwangsweise in die Sowjetunion repatriiert.

Einzelnachweise

Weblinks

Stadtteil von Neapel

redpajama_set_name: RedPajamaWikipedia


The Senior Center provides a variety of services to the community. Examples include Information and Referal, Benefit Screening/Application Assistance, Group Support, SHINE Medicare Counseling, and Danvers Triad. Click the icons below to learn more.
If you have more questions you can call us at 978-762-0208.


text:
United States National Youth Risk Behavior Survey 2009
Microdata access: Download
United States National Youth Risk Behavior Survey (YRBS)
Nationally representative
Subnationally representative
The United States National Youth Risk Behavior Surveillance System (YRBSS) was developed to provide data on health risk behaviors and the prevalence of obesity and asthma for representative samples of 9th through 12th grade public and private school students in the United States. Youth Risk Behavior Surveys (YRBS) are implemented at the national level by the Centers for Disease Control and at the state, territorial, tribal and local levels by area departments of health and education. Conducted every 2 years, the YRBS includes a national high school, local high school, and middle school questionnaire that collects information on physical inactivity, alcohol and illicit drug use, unhealthy diet, and behaviors that contribute to STDs, unintended pregnancies, injuries and violence. For the 2009 YRBS, 16,460 national questionnaires were completed in 158 schools and 42 state, and 20 local surveys were conducted with sample sizes ranging from 965 to 14,870.
Adolescents, Age at first sex, Alcohol use, Asthma, Birth control pills, Condoms, Contraceptives, Drug consumption, Education, Ethnicity, Fruits and vegetables, Health education, Height, Illicit drug use, Injectable contraceptives, Interpersonal violence, Intimate partner violence, Leisure activities, Lifestyle risk factors, Mass media, Mental and behavioral disorders, Physical activity, Preventive interventions, Race, Reproductive and sexual risk factors, Safety, Seat belts, Self-inflicted injuries, Sexual abstinence, Sexual behavior, Sexual violence, Sleep, Tobacco, Tobacco smoking, Traditional birth control, Violence, Weight, Smokeless tobacco use, Body mass index, Bullying, FFQ
Centers for Disease Control and Prevention (CDC). United States National Youth Risk Behavior Survey 2009. Atlanta, United States of America: Centers for Disease Control and Prevention (CDC), 2010.
GHDx Entry last modified on: Aug 5, 2021

redpajama_set_name: RedPajamaCommonCrawl


text:
Teen activist Thunberg urges leaders to admit climate crisis
by: FRANK JORDANS, Associated Press
Posted: May 28, 2019 / 11:41 AM EDT / Updated: May 28, 2019 / 02:21 PM EDT
United Nations Secretary-General Antonio Guterres, Swedish climate activist Greta Thunberg, Austrian President Alexander Van der Bellen and former California Gov. Arnold Schwarzenegger, from left, pose before the R20 Austrian world summit at Hofburg palace in Vienna, Austria, Tuesday, May 28, 2019. (AP Photo/Ronald Zak)
BERLIN (AP) — Teenage climate activist Greta Thunberg called on world leaders Tuesday to acknowledge the seriousness of global warming and that not enough is being done to curb it.
Speaking at a conference in the Austrian capital, Vienna, Thunberg suggested it was wrong to portray the worldwide shift necessary to rein in climate change as "primarily an opportunity to create new green jobs, new businesses, green economic growth," as some political and business leaders have done.
"This is above all an emergency and not just any emergency. This is the biggest crisis humanity has ever faced," she said, adding: "This is not something you can like on Facebook."
The 16-year-old's activism, which started with her protesting alone in front of the Swedish parliament last August, has inspired regular student protests around the world. Green parties in Europe have credited Thunberg with helping propel the issue of climate change into the limelight, boosting their results in last week's European Parliament elections.
Thunberg has often struck a much darker tone than some of her fellow activists and refused to hold back from criticizing her audiences.
"Politicians one second say climate change is very important, it is the most important topic and we are going to do everything we can to stop it," she said. "And the next second they want to expand airports, build new coal power plants and motorways. And then they fly off in a private jet to attend a meeting on the other side of the world."
U.N. Secretary-General Antonio Guterres, who has invited world leaders to a climate summit in New York in September, said countries aren't doing enough to meet the Paris climate agreement's goal of keeping global warming well below 2 degrees Celsius (3.6 Fahrenheit) by the end of the century compared with pre-industrial times.
Guterres called for an end to fossil fuel subsidies, saying taxpayers' money shouldn't be used to harm the planet.
"Many people still think that to give fossil fuel subsidies is a way to improve living conditions of people," he said. "Nothing (could be) more wrong. What we are doing is to use taxpayers' money, which means our money, to boost hurricanes, to spread drought, to melt glaciers, to bleach corals, in one word: to destroy the world."
"I believe that as taxpayers we would prefer to see our money back than to see our money used to destroy the world," said Guterres.
More Uncategorized Stories
US 42 between SR 736 and Hickory Ridge Road reopens after crash
UNION COUNTY (WCMH) – Authorities say US 42 is back open after a crash.


Simply follow the steps below to register your loyalty card or download the 'My New World' app straight to your mobile device.
Cards must be registered within 28 days of first use to be valid. If you'd like to ask any questions on this process, please email myrewards@nwtc.uk.com.


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Toronto, ON (February 13, 2014) — NexJ Systems Inc., (TSX: NXJ), a provider of cloud-based software, delivering enterprise solutions for the financial services, insurance, and healthcare industries, today announced that financial results for the fourth quarter and fiscal year-end 2013 will be released on Thursday, February 27, 2013 at approximately 4:00 p.m. ET.
A replay of the call will be available beginning February 27, 2014 at 8:00 p.m. ET through 11:59 p.m. on March 3, 2014 and can be accessed by dialing 1-855-859-2056 and using password 29926948.


Last edited by b100w11 on Fri Dec 15, 2006 10:41 pm, edited 1 time in total.
I want only to say Welcome to EBT board. I hope to see your euro coins here and have a hit with you!
Just a warm WELCOME to all Slovenian EBT-users !!!!
And -of course- also to those who are curious about this community.
Feel free to ask things you want to know about EBT.
Welcome to all the Slovenians.
I have an idea for promoting EuroBillTracker in Slovenia.
You could mail to the Slovenian media, so they can also say something about EuroBillTracker on the first of januari, when the Euro is big news in Slovenia. You can associate the Euro with EuroBillTracker in the media.
Regardnig the promotion of EBT in Slovenia! It won't be nessecary. Everything connected with the euro after jan 1st will be very popular in SI (looking and collecting coins with different national sides, watching shows regarding topics on TV, everything on the internet incl. EBT etc like you had in 2002).
Thanks to my slightly distant current location, I'm probably not gonna get any hits with Slovenia, but what the heck. Still cool to have new people among us!
And about advertising.. Of course everything related to Euro will make a top story, but it won't help if nobody ever mentions the press that EBT exists. So, send those messages to the reporters.
I would like to welcome Slovenia into the eurozone in the end of this month. Hopefully many people will track eurobills in this beautiful country. Unfortinatly I forgot to track any euro's when I was there in 2005 (I wasn't that fanatic at that time, and more interrested in the Tolarjev coins).
Personally I like tracking eurobills in as many locations as possible. A nice tool to see the statistics is NIG. It contains many locations information, like municipalities or provinces. I have created a file that calculates the Slovenian postcodes into municipalities (Občina). Hopefully it will be available in the NIG download soon.
I hope I haven't made to many mistakes, as I don't speak much Slovenian and based my information on wikipedia and posta.si.
Dakkus wrote: And about advertising.. Of course everything related to Euro will make a top story, but it won't help if nobody ever mentions the press that EBT exists. So, send those messages to the reporters.
Exactly. If things are going now in Slovenia as they were in Portugal when Euro was being launched this is precisely the best time to send press realeases.. Press will grab anything Euro-related Just send a few e-mails to newspapers, Tv.. there are only 5 slovenian users this month, we want more!
and soon welcome to the eurozone! I hope EBT will be as great as in Finland!
AND let's hope meeting each other at the next EBT-Meetings!!!


text:
Richard Brown The Engineer'S Office
Gallery -> Richard Brown -> The Engineer'S Office
My Biography View the Richard Brown Gallery
The Engineer'S Office
14h x 17w
Heavy freight has always been the basic work of railroads, generating the majority of train miles. Throughout the first half of the twentieth century, railroads were the veins and arteries of the North American economy.
And steam locomotives in particular were the backbone of rail operations for 120 years (1830-1950), the period in which our industrial economy reached full maturity.
Skill of the steam-era crew member – engineer, fireman, conductor, or brakeman – was key to this
growth.
Glamour may have gone to the crew on the fast express. But it was the crew on the heavy freight that earned the railroad's keep.
This image is my acknowledgement of what happens behind the scenes.
If freight is what pays the bills, then the engineer's office is where the work was done.
The boiler idles at 150 psi; the throttle is the diagonal lever; two brake handles are at the lower right; and the water glass and gauge cocks are at upper left.
The Engineer's Office was drawn in graphite and carbon pencil on 14" x 17" Strathmore Bristol Vellum.
Midland, Ontario
Canada, L4R 4L3
Enter your contact info reguarding The Engineer'S Office below!


text:
Adam Gerstenfeld
Share Three Takeaways for Charter Schools from the 2019 School in America Report to TwitterShare Three Takeaways for Charter Schools from the 2019 School in America Report to Facebook
Over the last few years, public charter schools have faced increasing hostility in state and federal legislatures and in the media. A once bipartisan issue has become emblematic of partisan politics, highlighted by the release of several anti-charter platforms from candidates for the Democratic presidential nomination.
While choice in education has become more polarizing, the release of EdChoice's seventh annual report on public opinion of schooling suggests that students and their families have maintained solid support for charter schools.
Here are a few things we learned on parent opinion and charter schools:
Parents are more satisfied with charter schools
The report shows parents who have enrolled their children in a charter school are more satisfied with that choice (77%) than families who have enrolled their children in a district school (67%). This has been a consistent and widening trend over the last several reports. In general, parents—regardless of where they send their children to school—are more likely to rate charter schools with an "A" or a "B" (61%), than they are to rate district schools with an "A" or a "B" (48%).
Bottom line: parents want choice in their communities—and when given that choice, they are usually satisfied with the results.
Parents are choosing charter schools for a reason
The report also lists reasons why parents turn to charter schools. According to the survey results, the top three reasons why parents choose charters are their academic reputation (32%), proximity to home/work (28%), and a safe environment (27%). For comparison, proximity to home/work (49%), assigned school (37%), and peers/socialization (32%) are the top three reasons parents indicated they choose a district school.
While parents may have opted to live in the area of the district school in question, the fact that over a third stated that their decision was due to assignment rather than active choice suggests that there may be unmet demand for charter schools. This is underscored by the fact that real-world enrollments do not match parents' first choice for enrollment:13 percent of parents said sending their children to charter schools would be their first choice, even though only 5 percent of parents surveyed actually had a child in a charter school.
Increased knowledge of charter schools leads to increased support
Additionally, the report highlights a key aspect of the debate on charter schools—as people become more informed about what charter schools are, their approval for them increases.
This year reflected the highest support for public charter schools since the report's inception. When given a description on charter schools, public support ticks up by 13 points, to a 64% approval rating. Teacher support increases to majority support after a description, up six points to 55%. Current school-age parent approval rating hits the highest mark of all with almost 70% of parents favoring charter schools after hearing a definition.
This is part of a growing trend we see with charter schools—as people learn more about them and experience them, support grows.
Taken together, these three takeaways show that parents want more educational opportunities for their children and, as charter schools continue to receive negative attention in media and political arenas, it is important that charter school advocates voice their support and take opportunities to counter misconceptions and misinformation. Charter schools have a unique opening to show they are putting student needs first—and advocates should take this opportunity to provide an accurate picture of the school choice landscape.
Adam Gerstenfeld is the manager, data and research for the National Alliance for Public Charter Schools.
Top 10 Posts on The Charter Blog in 2019


We tend to think about our healthcare sector as a leader in the development and use of advanced medical technology and biotechnology, such as expensive imaging machines or devices that we implant into patients.
But in many aspects of conducting the business of healthcare, our healthcare system is still in a pre-digital era. For example, healthcare may be the last sector where significant amounts of communication are still done via fax and regular post.
This is not to say that significant changes are not happening. Radiology is increasingly using digital technology but the interpretation of these images is still manual. Electronic health and medical records are also being introduced widely but there is little communication between collectors.
The digital revolution in healthcare that is currently slowly unfolding will use data and technology to improve the healthcare of patients. It will also increase safety and quality, and improve efficiency in the healthcare system.
One example of how technology can be used to deliver better healthcare is a recent trial by CSIRO and our partners that provided screening for eye diseases among people in remote parts of Western Australia and Queensland.
Using the NBN's satellite broadband service, we screened more than 1,200 people in their communities for diseases such as diabetic retinopathy. This disease often causes irreversible blindness, and it affects the Indigenous population at nearly four times the rate of the non-Indigenous population.
Local health workers were trained at capturing high-resolution images of a patient's retina with a low-cost retinal camera. These images were stored then uploaded over the NBN satellite to ophthalmologists in Brisbane and Perth.
The screening program identified 68 patients who were at high risk of going blind, including those with macular edema. In the most case these patients received treatment locally. However, some patients needed transfer to major hospitals for immediate treatment.
Once patients were identified as being at risk of significant eye disease, they were provided with care plans that involved local follow up consultations and regular screening the tele-eye care screening program.
For diabetic patients this included advice on controlling their diabetes, which improves their overall health as well as reducing the risk of blindness.
Overall, the trial showed the effectiveness of providing a "store and forward" tele-ophthalmology service using satellite broadband. These types of services have previously been held back by unreliable broadband services and the lack of digital systems in our health services to interact with them.
Reliable broadband connectivity together with increased use of digital systems by health services means that these methods of health service delivery can now become the normal way healthcare is provided.
But for these tele-enabled models of care to really take off, patient data must be shared between providers. At the moment, different healthcare providers – GPs, specialist doctors and emergency departments at local hospitals – all separately collect information about the same patients.
This means that the services that a patient receives are generally uncoordinated. With the increase in chronic diseases, such as diabetes and eye-disease, coordinated care will lead to better health outcomes.
For providers to share data requires their computer systems to be able to send and receive data, and make sure that the data is added to the correct patient's electronic record.
This is where the type of algorithms that power search engines such as Google – semantic web and information retrieval technologies – can be tailored for healthcare systems. Shared properly, the data can be used to make sure that patients receive appropriate services.
Sharing this data will also mean that there is a bigger volume of data about a patient with each healthcare provider. This will require computers to do more to analyse the data and alert patients, clinicians and health care providers when there should be follow up action.
The increase in the use of digital technologies will not only boost healthcare. This is a sector where there will be a significant boost in the number of IT professionals, including data scientists, needed to work.
Big data analytics will be required to analyse the large volumes of different types of data that are being collected at an increasing rate.
But it is not just about applying these new technologies in healthcare. There is also a need to work with clinicians and health service executives to understand what data is – or could be – collected. This may lead to a new way of providing clinical care, a new health service, or even make existing processes more efficient.
For data analysts and IT professionals working in healthcare, the opportunities to make a difference to patients are almost boundless.
David Hansen is CEO, Australian e-Health Research Centre at CSIRO.
It's safe to say that the only constant in this space is change. Research suggests that expectations for more personalised, better and faster services and more well-designed experiences will continue to increase.
Virtual tours are now possible at the National Museum of Australia.
Australia's eight national, state and territory art organisations hold archives that, if laid out flat end-to-end, would span 629km. This is on top of a staggering 100,000 million artworks, books and audio-visual items in Australia.
As a country, not only do we need to get moving when it comes to digitising our collections, we also need to explore new and innovative ways to do this. Traditionally, digitisation has meant scanning flat documents, photographing objects or creating electronic versions of catalogue data.
There are about 28.5 million head of cattle in Australia. Each one produces between ten and 12 cowpats a day, at an average 2.5kg each. Over a 14-day period, that's about 14 million tonnes of dung. And every one of those cowflops can generate about 3000 flies in that time. But you may have noticed that Australia hasn't been buried in manure or completely blanketed in flies. That's because, for more than 40 years, we've been working to make sure cow dung doesn't hang around, polluting pastures and waterways and providing the ideal breeding ground for flies.
This is a special week for us. One of our two new species of European dung beetle is ready for field release. The other is planned for release in 2015.
Our scientist, Dr Jane Wright, personally carried her shy but important companions, Onthophagus vacca, (a native of France and Spain) from Canberra to Western Australia. The spring-active dung beetles will be burrowing into new homes at field sites around Kojonup in Western Australia. These sites were chosen because they are home to numerous large herds of cattle, which means a lot of cow dung is available.
Here they are, making themselves at home.
Up until now, there has been a gap between one species of beetle settling down for a well-earned break and the next gearing up for action. These new beetles have been carefully selected to fill the seasonal break in activity in early spring across southern and western Australia. By introducing the spring-active beetle, the long term goal is to ensure dung is buried in early spring, getting the nutrients into the ground and accessible to the plant roots. The result is increased pasture productivity and reduced runoff of nutrients into waterways. Another benefit is that the beetles will compete with bush flies for the dung, thus slowing the buildup of fly numbers over spring, enabling the existing beetles to have a greater impact on fly populations over summer.
With financial support from Meat and Livestock Australia and WA Agriculture and Food, we imported two new species of dung beetle in 2012. These were placed in quarantine and set up to breed. Then their eggs were surface-sterilised following AQIS protocols. Following that the eggs were taken into the laboratory outside quarantine and transferred to artificial brood balls. These beetles were the start of a laboratory colony that has allowed us to produce sufficient beetles for field releases, like this one.
If you'd like to learn more about these little scuttling wonders, there's a more in-depth article over at The Conversation.
Recently speculation has been rife that the end of 2014 will see an El Niño event — the change in Pacific ocean and atmosphere circulation that is known to produce drought, extreme heat, and fire in Australia. The Bureau of Meteorology's latest statement predicts that Pacific Ocean temperatures may approach El Niño levels by early winter, but the jury is out beyond the end of this year.
Given the catastrophic effects El Niño can have, should we be getting prepared anyway?
An El Niño for 2014?
A small number of models have predicted an El Niño later in the year. But these models generally suffer from what scientists call an "autumn predictability barrier". During the southern hemisphere autumn it is hard to distinguish the development of an El Niño from background variability.
But a recent high-profile paper in Proceedings of the National Academy of Sciences adamantly predicted an El Niño later this year, using a new framework that explores how ocean temperatures are connected between the equatorial Pacific and other regions. The paper claims to overcome the autumn predictability barrier, quoting a 70% success rate in simulating prediction of historical El Niño events.
To better ready ourselves for an El Niño event, we need to know what the impact might be. El Niño affects our lives in many ways.
One important consideration is Murray River, which supports economic activities estimated at tens of billions of dollars each year, including our irrigated agriculture and water supply in regional areas.
El Niño can also happen in conjunction with other climate cycles. When an El Niño coincides with the positive phase of the Indian Ocean Dipole, there is usually a dramatic reduction in annual inflow.
A prediction of an El Niño will trigger consideration of water allocation by our water managers, taking into account of the need for environmental flow to ensure the long-term health of the river.
Another consideration is drought, which has a direct impact on our ecosystems and farming communities. Our farmers are very skilled in using El Niño prediction information. They use the information to decide what crops to plant and level of cropping activities. Sometimes it is better not to grow anything, to limit losses.
An incorrect prediction can be costly too. So our farmers make ongoing decisions using updated information (normally on a monthly basis). From time to time they will need help to get through tough times, and so our federal government needs to budget for drought relief.
A further consideration is extreme weather. More heatwaves, bushfires and dust storms will have an impact of human health, infrastructure, and emergency services. For example, our senior citizens are most affected by heat stress.
In the week of the recent January heatwave in Victoria, the number of deaths more than doubled. It's a common-sense matter of getting well prepared to ensure relief is available when needed. If a cooler is needed, it is too late to install it after you hear the weather forecast.
This year, and in summer 2013, southeast Australia experienced significant and unprecedented heatwaves, both associated with bushfires. These kinds of events usually take place in an El Niño year.
In fact, an average El Niño increases the global mean temperature by 0.1C. One example is the extreme El Niño of 1982-83, in which a string of heatwaves preceded the Ash Wednesday bushfires, amid severe drought conditions.
But 2013 and the summer just past were not a result of El Niño. In fact these record-breaking heatwaves occurred at a time when the increase of global surface temperatures has slowed, although regionally temperatures continue to increase. Inland Australia — the source of heat in south east Australian heatwaves — continues to warm.
The reason for the slowdown in the rising global surface temperatures is another ocean and atmosphere cycle: the Pacific Decadal Oscillation (PDO). Currently in a negative phase, the PDO is encouraging heat to be stored in the ocean thanks to changes in trade winds. Likewise, during a positive PDO, less heat is stored in the ocean, which can enhance the effect of El Niño as in the 1982-83 event.
So there are a range of scenarios depending on a number of different climate cycles. Imagine this one: global warming continues unmitigated by a "hiatus", and then an El Niño or extreme El Niño occurs. Such an alignment of warming, positive PDO and El Niño is likely to occur several times over the next 20 years. While we can't predict exactly when the PDO might shift to a positive phase, we might expect the current negative phase to last another four to five years.
If we didn't like what we experienced in 2013 and early 2014, we're unlikely to enjoy this worst-case scenario. Heatwaves will be not only more frequent, but hotter too. The associated drought would eventually break, but it will be longer and more severe. Are we ready?
Cathy Foley reflects on her time as Woman of the Year.


text:
Homestead Post-Race Report
No. 34 Speedco/Rotella Ford
Started: 24th | Finished: 28th
2018 Points Finish: 26th
"We had a really fast Speedco/Rotella Ford, but unfortunately we had a couple flat tires that caused us to pit under green and lose laps. But, everybody did a good job. We had a good season. It's a shame we didn't get to finish it off with a top-20 run, but we had a car that could've done it. We're already looking forward to 2019."
McDowell on Homestead: 'You Run All Around'
McDowell on Homestead"Homestead is a great racetrack just because you run all around. You can run the fence, or I was able to run the bottom last year and had a pretty decent finish. You definitely have options there. More than anything, the season's winding down and there's a lot of excitement around Ford Championship Weekend. Obviously, we're not in the playoffs, but hopefully we can do everything we can to get a Ford back into Victory Lane and a championship. They've had the speed this year, so hopefully they can finish it off.
"We have Speedco and Shell Rotella on our No. 34 at Homestead, which are part of the Love's family. We've had a great season with Love's Travel Stops. They're such a great partner to work with, and they know how to use their program with Front Row Motorsports to enhance their business relationships. We had a good finish last weekend at Phoenix, and we'll fight hard to end the season with another good finish for them."
McDowell Homestead Stats
8 starts, 1 top-10
Sunday, Nov. 18, 10:20am - Ford Performance display (Homestead Miami Speedway Fan Zone)
Phoenix Post-Race Report
No. 34 Love's/Luber-finer Ford
Started: 23rd | Finished: 16th
""It's definitely the best run I've had here, and I'm really proud of the guys. I made mistakes on pit road instead. It's kind of a trick pit road now with curves and straights, and I was just pushing it too hard. We were able to rebound. I'm glad to get a top-20 with our Love's/Luber-finer Ford and get some momentum back going to Homestead."
McDowell Says ISM Raceway Changes Could Impact Finish
McDowell on Phoenix"Nothing about Phoenix is a short track anymore. I'm just excited to go see what they've done there with all the renovations and all the effort that's gone into revitalizing Phoenix. It's such a great track, and it's my hometown race. The fans there are incredible. We always have a huge turnout. We've got Luber-finer back with Love's for a second race, so we want to get them some attention at my home track.
"I've tried to wrap my head around the idea of not knowing where the start-finish line is. There's so much muscle memory and rhythm and habits. The track's probably still going to feel the same. I'll probably still call it Turn 1. But the start-finish line being on the other side is going to change up restarts and finishes and overtime lines. But overall, you're going to approach everything the same.
"It could make for a crazy finish coming out of that corner. And that's why they did it, to create a little bit of drama. We've seen a lot of green-white-checkereds there in the past. You think about Ryan Newman and some other guys that have stolen some wins there by staying out. It's a place where you can do that. You've just got to time everything just right."
McDowell Phoenix Stats
Best finish: 22nd
Texas Post-Race Report
No. 34 Love's/Luber-finer Ford
"It took us the early part of the race to get the Love's/Luber-finer Ford handling the way we wanted it to. After that, we had pretty good speed. Unfortunately, we had two pit road speeding penalties early on that really hurt us and were tough to recover from. But the team made good adjustments, and we'll get back on track for Phoenix and finish these last two races strong."


Do you wish to improve your genealogy research skills? Whether you're a beginner or an intermediate-level genealogist, you have room to hone your skills to make your research better, more accurate, and more thorough, so you can discover more about your ancestors. There are books you can read on the subject, and they can be quite helpful in improving your skills. However, nothing is quite like improving your skills through a class.
You will actually get hands-on practice that will help you remember what to do when you're out in the field doing it on your own. You don't have to go to a college or adult education facility to take a genealogy research class. The Internet offers plenty. Here are the three best ones you should consider taking if you are serious about getting your research skills to the next level.


text:
Schima is a genus of evergreen trees belonging to the tea family, Theaceae.

The genus inhabits warm temperate to subtropical climates across southern and southeastern Asia, from the eastern Himalaya of Nepal and eastern India across Indochina, southern China, Taiwan, and the Ryukyu Islands. There are about 30 species, 21 species distributed in China (six endemic), among which Schima superba is the most common.

Fossil record
Fossil fruits of Schima have been described as †Schima nanlinensis, from the Miocene of Nanlin Formation in Longchuan Basin, Dehong Autonomous Prefecture, Yunnan Province, China. The fossil fruits are 5-loculed capsules with flat reniform seeds. The genus Schima is known as fossils from the Palaeogene and Neogene of Germany and Austria. †Schima nanlinensis represents the first fossil record of the genus in Asia.

Species (accepted)
 Schima brevipedicellata Hung T. Chang
 Schima crenata Korth.
 Schima khasiana Dyer
 Schima multibracteata Hung T. Chang
 Schima noronhae Reinw.
 Schima parviflora W.C. Cheng & Hung T. Chang
 Schima remotiserrata Hung T. Chang
 Schima sericans (Hand.-Mazz.) T.L. Ming
 Schima sericans var. paracrenata (Hung T. Chang) T.L. Ming
 Schima sinensis (Hemsl. & E.H. Wilson) Airy Shaw
 Schima superba Gardner & Champ.
 Schima villosa Hu
 Schima wallichii Choisy

Species (unresolved)
 Schima argentea E.Pritz. ex Diels
 Schima bambusifolia Hu
 Schima bancana Miq.
 Schima beccarii Warb.
 Schima boninensis Melch.
 Schima boninensis Nakai
 Schima brevifolia Baill. ex Stapf
 Schima dulungensis H.T.Chang & C.S.Ye
 Schima excelsa Blume
 Schima hypochra Pierre
 Schima hypoglauca Miq.
 Schima lobbii (Hook.f.) Pierre
 Schima lowii Pierre
 Schima mairei Hochr.
 Schima mertensiana Koidz.
 Schima mollis Dyer
 Schima monticola Kurz
 Schima oblata Kurz
 Schima polyneura H.T.Chang
 Schima pulgarensis Elmer
 Schima rigida Miq.
 Schima sericea Airy Shaw
 Schima sulcinervia Miq.
 Schima wallichii (DC.) Korth.

References

 The Plant List entry

Theaceae
Ericales genera
Flora of Nepal


With the onset of Summer, many of us get conscious of the body. We want to have a "bikini-ready" body even if we don't wear a bikini. We just want to feel good, be fit and happy. For many, the task of losing excess weight can become disheartening, especially if there is a lot to shed. But getting a step ahead, engaging in exercise routines, and eating smart and right means you can sooner achieve the bikini body you have been aiming.
The Vanquish treatment is one of the latest FDA-approved nonsurgical procedures that treat stubborn fat deposits. The procedure utilizes radiofrequency that initiates a programmed death of fat cells at the superficial fat layer of the skin. However, this treatment is only best for small fat reductions on the abdomen and thighs.
During the treatment, patients lie underneath a machine with adjustable panels. The apparatus heats the underlying fat to 120°, eliciting a warm feeling to patients undergoing the procedure. One treatment session lasts for 30 to 45 minutes with the successive sessions one week after other.
3D Liposuction is another advanced non-surgical procedure available to patients who want to sculpt their body. This procedure is best in shaping the body, particularly the upper arm, around the neck and jawline, abdomen, inner and outer thigh, flanks, and the buttocks.
3D Liposuction lasts for 30 minutes to an hour and a half. Depending on your desired results, plastic surgeons recommend at least six to eight session with an interval of one week per session. Moreover, it combines four body contouring methods in one treatment: fat freezing, ultrasound cavitation, radiofrequency, and dermology.
Cryolipolysis – Known as fat freezing, this procedure uses cold temperature to eliminate fat cells. During cryolipolysis, a vacuum application is placed on the treatment site and freezes the surrounding skin to about -6°C. At this temperature, the water content of fat cells solidifies and triggers the cell to undergo programmed cell death. The cells are then disposed through the body's elimination processes.
Ultrasound Cavitation – This method uses transducer plates that emit low-frequency ultrasound after the application of a gel over the target site. The low frequency ultrasound initiates the formation of bubbles in the fat cells, which causes them to collapse due to extreme heat and pressure. The destroyed fat cells are then excreted as waste from the body.
Radiofrequency – Radiofrequency is usually performed on smaller areas. Temperature ranging from 38° to 41° is applied to the treatment site, causing fat cells to liquefy. It also targets the skin layer where collagen and elastin are abundant. Radiofrequency is beneficial if you also want to have smoother and firmer skin as it stimulates the production of collagen and elastin while inducing fat reduction.
Dermology – Dermology works in two ways: it refines the skin and reduces the cellulite in the target areas through the roller and vacuum suction action of the applicator. Other benefits include increased and improved blood and lymph circulation.
The most popular FDA-approved non-invasive body contouring procedure is CoolSculpting. Based on the science of cryolipolysis, it utilizes cold temperatures to solidify fat cells, causing them to die and be discharged through the body's lymphatic system. CoolSculpting can be used on stubborn fat bulges found in the chin, arms, abdomen, thighs, flanks, back, and buttocks.
During CoolSculpting, a vacuum applicator that lightly pinches the target area administers the cold temperature to freeze the fat cells just beneath the skin. The cool temperature prompts the fat cells to crystallize and disintegrate. Afterward, the treated site is briefly massaged to reduce swelling. CoolSculpting lasts for an hour but may take longer depending on the number of areas to be treated.
A well-planned workout and eating a healthy and balanced diet are undoubtedly still the best techniques to have a beach-ready body. But the aftereffect of such a lifestyle can be further improved through non-invasive body contouring treatments like Vanquish, 3D Liposuction, and CoolSculpting. These non-surgical treatments can help you achieve your desired body contour without the inconvenience of having a lengthy recovery period.
But before going for these procedures, be sure to take the time to think things through. Consulting with a plastic surgeon is the best course of action to ascertain your suitability for each treatment. Their extensive study and training allow them to expertly suggest the best type of treatment that can help you achieve an aesthetically attractive and beach-ready body!


Tattoo Care Sunscreen, Ointment for Tattoo Sun Protection, UVA UVB SPF 30+ 50+ Sunblock, Natural Ingredients, Highlights Tattoo Colors, Inked and Tanned, Sun Sleeves, Convenient Beach Tube, 1,35 oz.
Product prices and availability are accurate as of 2019-04-22 17:42:13 UTC and are subject to change. Any price and availability information displayed on http://www.amazon.com/ at the time of purchase will apply to the purchase of this product.
A unique ointment with an active formula and special structure with high ink and high skin protection. This new formula doesn't just block out the sun's harmful UVA and UVB rays but also puts a second ink-barrier to help keep your tattoos and skin safe.
Sun is the worst enemy of tattoos. It has been proven to have the strongest impact on the tattoo fading, changing ink colors, and ageing of skin. Tattoo Care Sun Protection with SPF 30+ gives your tattoo double protection. It actively helps prevent color fading and tattoo ageing, and its structure gives your skin a high level of protection and long-lasting water resistance.
Tattoo Care Sun Protection is made from carefully selected natural ingredients including Calendula, Cocoa Butter, Bisabolol, Almond and Jojoba oil, Vitamin E and more. It has been developed by Pharmacists and professional Tattoo Artists; dermatological testing shows that our skin tolerates it very well. It contains no parabens or allergens and was not tested on animals. It is also suitable for everyday skin care.


Game Shape Revitalized Rubber Products helps us all meet the growing commitment to creating a cleaner planet. Game Shape is made from recycled rubber. The majority of Game Shape products contain approximately 90% post consumer waste rubber and one is manufactured from 100% recycled rubber.
The use of Game Shape Revitalized Rubber Products helps reduce the mountains of tire casings polluting soil and streams all over the world. Game Shape Products are environmentally friendly by today's standards and we believe will continuue to be in the future because it can be recycled at anytime without detrimental effects to the environment. Specifying Game Shape products is a great way for a school, company, organization, government agency, or any of us as individuals to demostrate a commitment to saving the Earth for the children of today and the children of tomorrow.


Lifestyle Deals are available across Spain and the Islands offering quality daily deals and offers to hundreds and thousands of members throughout Spain, in English, Spanish & German. Lifestyle deals offer you a way of trying something new letting you find the best things to do in your local city with up to 70% off. Enjoy Spain at a fraction of the cost.
It is totally free to join. We love what we do & we live what we do – we'll only ever tell you about the best quality deals & events because those are the same bars, restaurants, salons & local businesses that we love going to. Oh, and if you see us there, do say hello we are a friendly bunch!
We extensively advertise and market the offers and Deals – advertising on radio, newspapers and magazines along with on social networking sites in and around Spain in several languages.
Want to feature your business on Lifestyle?


Image Title: Hampton Bay Patio Furniture Outdoors The Home Depot Inside Daytona Beach Plan 10. Filename: hampton-bay-patio-furniture-outdoors-the-home-depot-inside-daytona-beach-plan-10.jpg. Image Dimension: 400 x 400 pixels. Images Format: jpg/jpeg. Publisher/Author: ungrounded. Uploaded Date: Monday - May 21st. 2018 04:38:26 AM. Category: Architecture. Image Source: housetohome.co.uk.
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Arkansas, Tennessee & South Carolina State QSO Party Contest Logs are Now Available!
Just in time for this weekend's contest, Tennessee QSO Party Contest Log 1.0 is now available! In addition, I've just completed logs for the Arkansas and South Carolina contests that are coming up in the next couple of weeks as well!
These additional programs, as always, are free to N3FJP Software Package users! Just enter the state QSO party password we sent with your package list and you will be all set!
Beta Testers Needed for AC Log and W4EPL's Interface to the DM 780 digital program!
Ed, W4ELP has been working hard, developing an interface between all my software, including AC Log and the DM 780 digital program. Ed's at a point where he really needs user feedback to move forward. If you have an interest in the digital modes, Ed would really appreciate your input!


text:
Q: How to get the second value of this xpath? Below is the html.

Electricity Bill Payment

Gas Bill Payment

I want to get the second h2 value i.e. "Gas Bill Payment". I wrote xpath as
//div[@id='pay-bills']//div//h2[@class='head ng-binding'][2]

The issue is I am unable to get the second value with "[2]". although when i insert "[1]" i get two values.

A: Why this doesn't work :
//div[@id='pay-bills']//div//h2[@class='head ng-binding'][2]

You're looking for an h2 element whith a position equals to 2. All h2 elements in your sample data are in first (1) position.
You can use the solution proposed by @chrisis or could go with :
(//div[@id='pay-bills']/div/h2)[2]/text()

Use () to specify you want the second displayed result of the XPath enclosed by ().
Be sure also to remove the unnecessary // from your expression (should be / since the second div and h2 are child elements).

A: Hope it may help.
>>> html = """

...
...

...
Electricity Bill Payment

...

...
...

...
Gas Bill Payment

...

...
...
"""

>>> html
'
\n\n
\n
Electricity Bill Payment
\n
\n\n
\n
Gas Bill Payment
\n
\n\n
'

>>> from pprint import pprint

>>> pprint(html)
('
\n'
 '\n'
 '
\n'
 '
Electricity '
 'Bill Payment
\n'
 '
\n'
 '\n'
 '
\n'
 '
Gas Bill '
 'Payment
\n'
 '
\n'
 '\n'
 '
')

>>> from scrapy.http import HtmlResponse

>>> response = HtmlResponse(url='my html string', body=html, encoding='utf-8')

>>> response.xpath('//div')
[<Selector xpath='//div' data='
, <Selector xpath='//div' data='
, <Selector xpath='//div' data='
]

>>> response.xpath('//div').getall()
['
\n\n
\n
Electricity Bill Payment
\n
\n\n
\n
Gas Bill Payment
\n
\n\n
', '
\n
Electricity Bill Payment
\n
', '
\n
Gas Bill Payment
\n
']

>>> response.xpath('//div//h2').getall()
['
Electricity Bill Payment
', '
Gas Bill Payment
']

>>> response.xpath('//div//h2').getall()[1]
'
Gas Bill Payment
'

>>> response.xpath('//div//h2/text()').getall()[1]
'Gas Bill Payment'

A: You want the second div, what you've tried would give you the second h2 inside the div if there was one.
Try
//div[@id='pay-bills']//div[2]//h2[@class='head ng-binding']

redpajama_set_name: RedPajamaStackExchange


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text:
MRD Reported Undetectable After Liso-cel CAR T-cell Therapy in CLL
In the phase I/II TRANSCEND CLL 004 study, chimeric antigen receptor T-cell therapy lisocabtagene maraleucel led to undetectable minimal residual disease in patients with relapsed/refractory chronic lymphocytic leukemia.
Tanya Siddiqi, MD
In the phase I/II TRANSCEND CLL 004 study (NCT03331198), chimeric antigen receptor (CAR) T-cell therapy lisocabtagene maraleucel (liso-cel; JCAR017) led to undetectable minimal residual disease (MRD) in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL).
Patients with CLL or small lymphocytic lymphoma (SLL) who had received 2 previous lines of therapy were given liso-cel at either dose level (DL) 1 of 50 × 106or DL2 of 100 × 106total CAR-positive T cells. Therapy was administered to 15 patients by liso-cel infusion, and 7 patients received bone marrow biopsies. These patients were then monitored for treatment-emergent adverse events, and doses were adjusted based on the emergence of adverse events.
Toxicities were manageable, with the most common toxicities including hypertension and cytopenias. Three patients had grade 3 neurotoxicity, and 1 patient presented with grade 3 cytokine release syndrome (CRS).
Phase II/III data presented during the 15th International Conference on Malignant Lymphoma (ICML) revealed that most patients (88%) had responses to therapy 30 days into the study. There was a high overall response rate (ORR; 83%), which was maintained for 6 months. Sixty-seven percent of patients had undetectable MRD by day 30.1
TRANSCEND CLL 004 showed that CAR T-cell therapy is a promising alternative for patients with CLL who failed previous forms of therapy. The study is ongoing, and the researchers expect to present a follow-up soon.
In an interview withTargeted Oncology, Tanya Siddiqi, MD, an assistant clinical professor in the Department of Hematology and Hematopoietic Cell Transplantation, City of Hope in Duarte, California, explained how novel agents are improving the treatment landscape for CLL with examples from the TRANSCEND CLL 004 trial.
TARGETED ONCOLOGY: How have novel agents changed the treatment landscape for CLL?
Siddiqui:There have been a lot of improvements in CLL therapy within the last few years, starting with ibrutinib (Imbruvica) and so many other agents coming down the pike. The latest advancement has been the venetoclax (Venclexta) plus obinutuzumab (Gazyva) CLL14 clinical trial, showing that the venetoclax arm is better than the chlorambucil plus obinutuzumab arm. [This result] was expected, but it's good to see it in hard data.
This is frontline therapy for patients with comorbidity, but in reality, I have a lot of patients who are younger and interested in finite therapy and even older patients who are interested in finite therapy since they don't want to be on ibrutinib indefinitely. It's a very good option as an alternative to sticking to 1 year of venetoclax plus obinutuzumab therapy and giving them a break to see what happens overtime. It's one of the best agents that have come out this year.
TARGETED ONCOLOGY: How do you see acalabrutinib (Calquence) fitting in to this space based on the results of the phase III ASCEND trial?
Siddiqui:It's an excellent option for patients to have if it does come on the market. We presume that acalabrutinib has a slightly better toxicity profile than ibrutinib, which means that it may have fewer hypertension events, bleeding events, and less atrial fibrillation events. All in all, I think it is a very good second option for patients to have if it comes to market.
It clearly showed that things look better with acalabrutinib than they do with idelalisib (Zydelig) and also with bendamustine (Treanda) and rituximab (Rituxan) combinations. Idelalisib isn't used that much in real practice, but this is the first time so far that a study has been reported comparing 2 novel agents to each other. There are a lot of studies ongoing, but nothing has been reported yet. So, for the first time, we are seeing that acalabrutinib is better than idelalisib which is great to know.
TARGETED ONCOLOGY: Are there any other recent developments outside of novel agents in the CLL landscape that you are excited about?
Siddiqui:CAR T-cells are the biggest thing. I presented the results of the Transcend CLL 004 study, which is a study in R/R CLL patients who have all failed ibrutinib previously. More than half have also failed venetoclax previously. This population is pretty poor-acting, so to speak, and are running out of options. Their disease behaves more aggressively. We treated 23 patients with liso-cel, and we found very encouraging results. [There was] a high overall response rate and high CR rate, and even undetectable MRD in the bone marrow and blood was pretty high at 60% to 65%, as early as 30 days after CAR T-cell therapy.
Overall, it's an excellent option. So far, we've seen about 3 or 4 patients beyond the 12-month mark who are still in a complete remission (CR) with detectable CAR T cell in their blood still and also undetectable MRD for CLL which is great. That's probably the most excited.
TARGETED ONCOLOGY:What was the rationale for conducting this study?
Siddiqui:We know that CLL is an incurable disease so far. We've come a long way to improve patient responses compared to just using chemoimmunotherapy. We take patients down to MRD undetectability with novel agents, especially combinations of novel agents. If we try to do fixed-duration novel agent therapy or monotherapy with ibrutinib or venetoclax alone, for example, we can't get patients down to undetectable MRD that reliably. We also can't keep them at undetectable [MRD] reliably.
The thought was, is there a way to actually cure these patients? Can you actually get them undetectable to MRD and never have the CLL come back? One of the ways we thought would be a good idea is to use their own immune system and make CAR T cells out of their T cells and see if they can fight the CD19-positive CLL cells as we did for aggressive lymphoma.
We are seeing the results, at least with the liso-cel monotherapy, is extremely good on this trial. What's more encouraging to me is that others medical centers like the University of Pennsylvania and the Fred Hutchinson Cancer Research Center are doing CLL studies with their CAR T cells, but their monotherapy CAR T cells don't seem to yield results. They're now combining CAR T cells with ibrutinib to improve on those results, and looks like they are going to do that. We thought with liso-cel, the monotherapy results were fabulous, but now we are doing a phase I cohort in which we're adding ibrutinib to the liso-cel to see if we can improve patient response even further. It's exciting.
TARGETED ONCOLOGY: What have been some of the hurdles with integrating CAR T cells into CLL treatment?
Siddiqui:The biggest hurdle is there are so many good, easy oral options for patients so we have to be picky with the patients we take CAR T cells, at least initially until we know that we can cure them. By definition, we can't say that for sure until 5 to 10 years that we have cured them.
I think if patients have aggressive-behaving CLL, it usually comes with the poor-risk features, like deletion 17p and complex cytogenetics. Even the novel agents may not control that type of disease for too long. The argument against CAR T cells being a little more intensive and involved is that those [aggressive] cases might benefit from it a lot, whereas people who are doing good on "watch and wait" may never need treatment and we should leave them alone. For patients with deletion 13q or mutatedIgVH, if they don't need any aggressive treatment like CAR T cells, just leave them on their pills. I think that has been the biggest criticism with CAR T cells for CLL. It's such an easy disease to treat but not for that subset of patients that has aggressive CLL.
I've also seen research presented about complex cytogenetics and their effect in the CLL14 trial, and it seems like the complex genetics have reduced risk and weaker response to the novel agents, especially highly complex cytogenetics. Educationally, that's good for us to be aware of [so that] we can stratify or think about more aggressive treatments for the more bad-acting CLL cases like those with a high number of complex cytogenetics. It was very good to see that data.
TARGETED ONCOLOGY: What did the safety profile look like for liso-cel in the TRANSCEND CLL 004 trial?
Siddiqui:For the TRANSCEND CLL 004 study, we saw easy-to-manage CAR T-cell therapy-related toxicities. The majority of the grade 3 and higher toxicity was cytopenia from chemotherapy. The cytokine release syndrome and neurotoxicity are the main CAR T-cell therapy-related side effects we saw. About 70% of patients had some grade CRS, but only 2 of the 23 patients had grade 3 CRS and no grade 4 or 5 CRS. For neurotoxicity, there were about 39% of patients that had some neurotoxicity, but only 5 patients had grade 3 or 4 neurotoxicity events. There were no grade 5 neurotoxicity events. [Liso-cel] was reasonably well tolerated, or I should say very well-tolerated in this situation.
There were also about 4 tumor lysis syndrome (TLS) events. We didn't see that much TLS in the lymphoma trial, but when you have circulating, abnormal CLL cells in the blood, there's usually more of a TLS risk, like we saw with acute leukemia. We had 4 events of the 23 that were TLS. A couple of them were manageable with allopurinol (Zyloprim) and pills. There were a couple of patients who needed rasburicase and 1 patient who needed dialysis as well.
There were 2 dose-limiting toxicity (DLT) events on level 2. One was severe hypertension, which is unusual because CAR T cells usually cause hypotension, but in this case, it was very severe hypertension at the end of the DLT periods, [which was] around day 28. The other toxicity was some neurotoxicity that latest more than 7 days [and] became a DLT by definition. That patient also had grade 4 TLS, requiring the dialysis, which made is a DLT event.
TARGETED ONCOLOGY: What does the future look like for CAR T-cell therapy in CLL?
Siddiqui:It looks really good in the sense that there is definitely a space for it. I believe we proved that there are some patients who will do extremely well. If you look back to 2011, the first time I read about the CAR T cells was in theNew England Journal of Medicinepaper printed by University of Pennsylvania, and it reported 3 patients with CLL who had just failed every pos
sible line of therapy and they were given CAR T cells. Apparently, 2 of 3 patients are still in a CR 8 years later.
There is certainly something to be said about the potential for a cure in CLL, which is an incurable disease to-date. Secondly, 1 of the things we struggle with on a lot of trials for R/R CLL patients is that if we can get them to undergo through CAR T-cell therapy at earlier stages while they are still fit and haven't failed say, 5 lines of prior therapies, then, maybe we can have a better shot at trying to cure them.
For instance, in the second-line, if a patient failed a novel agent in the frontline and relapse, their prognosis is already poor. At that point, they can go straight to CAR T cells, and if that does the trick that's great. If it doesn't, you still have backup venetoclax or the alternative novel agents, PI3K delta inhibitors and other things down the line. If we can move it closer to frontline over time, that would be an excellent step for CLL.
Siddiqi T, Dorritie KA, Soumerai JD, et al. TRANSCEND CLL 004: Minimal residual disease after lisocabtagene maraleucel in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma.Hematol Oncol. 2019;37(suppl S2):109-110. doi: 10.1002/hon.71_2629.


text:
Texas Supreme Court Hears Case Challenging State's Smokable Hemp Manufacturing Ban
A Pennsylvania bill meant to promote research into the therapeutic potential of psilocybin mushrooms for certain mental health conditions may be in jeopardy, with the sponsor saying that the chair of a key House committee is expressing reservations even after the legislation was amended in an effort to build support.
The legislation from Rep. Tracy Pennycuick (R)—titled the "Psilocybin Data Act"—was originally introduced last year, but it did not advance. A revised version filed this month notably removes a key provision allowing state Department of Health to authorize two entities to cultivate the psychedelic for research purposes.
But the sponsor tells Marijuana Moment that the "watered down version" is still facing a major obstacle in the committee where it's been referred.
Pennycuick said that supporters are "struggling" with the chair of the House Health Committee, Rep. Kathy Rapp (R).
"I am not sure she will even run this," the sponsor said. "To say I am frustrated is mild compared to how I really feel. I have worked this bill for months."
Pennycuick said that she's been working to build support for the legislation for months, but then the chairwoman "shifted course due to an overdose death in her district" allegedly involving so-called "magic mushrooms."
Two points on that: First, the bill would not legalize psilocybin. Second, the psychedelic has a very low toxicity rate. The Drug Policy Alliance explains that "sensationalized media coverage of psychedelic-related deaths [have] misattributed the role of psychedelics like psilocybin in causing suicide or accidental death."
Rapp's office did not respond multiple requests for comment and clarification from Marijuana Moment.
"I don't understand it," Pennycuick, an Army veteran herself who lives with PTSD, said. "It is frustrating."
The lawmaker suffered a traumatic experience as an Army helicopter pilot, left stuck in a vehicle that caught fire following an explosion. She told Philadelphia Magazine that the psychological damage of that event "didn't hit me until five or six years later," and she hopes to be "patient number one" for psilocybin clinical trials as a therapeutic tool for her own condition.
Her newly revised bill, HB 2421, starts with a declaration of purpose stating that the Commonwealth is "in desperate need of innovative and cost-effective mental health treatment to combat this significant public health crisis," citing statistics about increased rates of mental health complications.
"A growing body of research suggests that psilocybin, administered in a controlled setting, may be the most effective tool at our disposal to combat this public health crisis," it says. "This Commonwealth, including this Commonwealth's substantial veteran community, will benefit from establishing a psilocybin regulatory system to combat the worsening mental health crisis."
The legislation would make it so the state health department would need to work with at least one academic institution to conduct clinical trials "for the purpose of collecting and studying the efficacy and cost-benefit optimization of psilocybin and psilocybin-assisted therapy in the treatment of mental health conditions and traumatic brain injury."
Beside traumatic brain injury, researchers would be tasked with investigating the therapeutic potential of psilocybin for PTSD, depression, anxiety, suicidal ideation, eating disorders, bipolar disorder, chronic pain, migraines and substance misuse disorders.
However, it stands to reason that those clinical trials might have been more easily facilitated with language from the original version authorizing limited cultivation within the state that has now been stricken.
That bill, HB 1959, originally contained a provision to permit at least two entities to "plant, grow and cultivate natural psilocybin mushroom product solely for use in the clinical studies of psilocybin."
That would no longer be the case under the revised bill.
Under the legislation, the department, in collaboration with an advisory board, would need to "issue interim reports every 180 days beginning 180 days after the effective date of this section on the data collected from the academic research institution… and a final report by December 31, 2025."
The final report would need to include results of any psilocybin clinical trials, an analysis of existing research into the psychedelic "and similar compounds," a description of federal and state laws concerning psilocybin.
It must also contain recommendations "for legislative actions or other actions to enact a framework for further research of psilocybin and similar compounds" as well as "legislative actions or other actions for the implementation of a regulatory system governing the use of psilocybin and psilocybin-assisted therapy with the goal of minimizing cost and maximizing the public health benefit of treatment."
In a cosponsorship memo released earlier this month, Pennycuick implored her colleagues to support the modest reform.
"It is my hope that this study is the first step in learning more about the benefits of psilocybin and what can be done in the future for the citizens of this Commonwealth who are suffering from mental health conditions," the lawmaker wrote.
There's no deficit of psychedelics reform proposals that are moving through state legislatures across the U.S. this session, in addition to activist-led efforts.
For instance, a Missouri House committee on Monday held a hearing on a GOP-led bill to legalize a wide range of psychedelics for therapeutic use at designated care facilities while further decriminalizing low-level possession in general.
A Connecticut legislative committee approved a bill last week that would set the state up to provide certain patients with access to psychedelic-assisted treatment with substances like MDMA and psilocybin. Connecticut Gov. Ned Lamont (D) signed a separate bill last year that includes language requiring the state to carry out a study into the therapeutic potential of psilocybin mushrooms. A workgroup has since been meeting to investigate the issue.
A Maryland House of Delegates committee held a hearing last week on a bill to create a state fund that could be used to provide access to psychedelics like psilocybin, MDMA and ketamine for military veterans suffering from post-traumatic stress disorder (PTSD).
The Washington State legislature recently sent a budget bill to the governor's desk that includes a proposal to direct $200,000 in funding to support a new workgroup to study the possibility of legalizing psilocybin services in the state, including the idea of using current marijuana regulatory systems to track psychedelic mushrooms.
This month, the Hawaii Senate approved a bill to set up a state working group to study the therapeutic benefits of psilocybin mushrooms and develop a "long-term" plan to ensure that the psychedelic is accessible for medical use for adults 21 and older.
Also this month, the Oklahoma House of Representatives passed a bill to decriminalize low-level possession of psilocybin and promote research into the therapeutic potential of the psychedelic.
A bipartisan coalition of Georgia lawmakers recently filed a resolution that calls for the formation of a House study committee to investigate the therapeutic potential of psychedelics like psilocybin and make recommendations for reforms.
Rhode Island lawmakers introduced a pair of drug decriminalization bills this month—including one focused on psilocybin and buprenorphine that would authorize doctors to prescribe the psychedelic mushroom.
Last month, Utah lawmakers sent a bill to the governor that would create a task force to study and make recommendations on the therapeutic potential of psychedelic drugs and possible regulations for their lawful use.
An Oregon Senate committee also recently advanced a bill to ensure that equity is built into the state's historic therapeutic psilocybin program that's actively being implemented following voter approval in 2020.
A bill to decriminalize a wide array of psychedelics in Virginia was taken up by a House of Delegates panel in January, only to be pushed off until 2023. A separate Senate proposal to decriminalize psilocybin alone was later defeated in a key committee.
California Sen. Scott Wiener (D) told Marijuana Moment in a recent interview that his bill to legalize psychedelics possession stands a 50/50 chance of reaching the governor's desk this year. It already cleared the full Senate and two Assembly committees during the first half of the two-year session.
Washington State lawmakers also introduced legislation in January that would legalize what the bill calls "supported psilocybin experiences" by adults 21 and older.
New Hampshire lawmakers filed measures to decriminalize psilocybin and all drugs.
Legislation was also enacted by the Texas legislature last year requiring the state to study the medical risks and benefits of psilocybin, MDMA and ketamine for military veterans in partnership with Baylor College of Medicine and a military-focused medical center.
A pair of Michigan senators also introduced a bill in September to legalize the possession, cultivation and delivery of an array of plant- and fungi-derived psychedelics like psilocybin and mescaline.
In a setback for the movement, California activists on Wednesday announced that they have come up short on collecting enough signatures to qualify a measure to legalize psilocybin mushrooms for the state's November ballot, though they aren't giving up on a future election cycle bid.
Colorado activists, meanwhile, recently selected one of the four psychedelics reform ballot initiatives that they drafted and filed for the November ballot, choosing to proceed with a measure to legalize psilocybin, create licensed "healing centers" where people can use the psychedelic for therapeutic purposes and provide a pathway for record sealing for prior convictions. A competing campaign filed a different psychedelics legalization last month.
Michigan activists filed a statewide ballot initiative last month that would legalize possessing, cultivating and sharing psychedelics and set up a system for their therapeutic and spiritual use.
At the congressional level, bipartisan lawmakers sent a letter to the Drug Enforcement Administration (DEA) last month, urging that the agency allow terminally ill patients to use psilocybin as an investigational treatment without the fear of federal prosecution.
50 Years Ago Today, A Federal Panel Said Marijuana Should Be Decriminalized—But A President Who Ran On Reform Still Hasn't Done It
Maine Should Decriminalize Drugs, Report From ACLU Says
Rhode Island House Panel Discusses Competing Marijuana Legalization Proposals From Lawmakers And Governor
Nebraska Officials Will Take A Second Look At Signatures For Rejected Medical Marijuana Ballot Measures
"We believe that it's essential that every signature from every Nebraskan be counted." By Paul Hammel, Nebraska Examiner…
Rhode Island Marijuana Legalization Bill Will Be Ready In Early 2022, Top Lawmaker Says
A top Rhode Island lawmaker on Thursday said that a bill to legalize marijuana in the Ocean State…
North Carolina Senators Approve Medical Marijuana Legalization Bill In Committee
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New York Marijuana Officials Are Now Accepting Applications For The First Recreational Dispensary Licenses
People who've been directly impacted by the drug war in New York are now able to submit applications…
Weedmaps Ad Satirizes Plight Of Broccoli Emoji As Marijuana Stand-In On Social Media
The marijuana technology company Weedmaps released a satirical ad on Monday about a man dressed as broccoli who's…
MD & DE legal cannabis bills advance (Newsletter: February 21, 2022)
Top NY lawmaker's PAC has marijuana focus; KY legalization bills; Wells Fargo: Fed cannabis policy hurts workforce; Canadian…


text:
H. Gradidge and Sons
of 36 Artillery Place, Woolwich, London, SE18. Telephone: Woolwich 0293. Cables: "Gradidge Wool"
1870 The company was founded by Harry Gradidge.
Later he was joined by his sons and the company became known as H. Gradidge and Sons.
The company specialised in the manufacture and distribution of cricket bats and was renowned for their quality and expertise in producing some of the finest bats of the time. (Their most famous player was Len Hutton who played for England and Yorkshire).
The company produced almost anything related to sport and kitted-out teams with all their sporting needs. A pricelist from 1911 for local football teams showed that "Jerseys are from 2/-, Footballs are from 7/6 and boots from 6/6 per pair."
1929 Listed Exhibitor. Manufacturers of Cricket Bats, Balls, Lawn Tennis, Real Tennis, Hard and Squash Rackets, and Balls. Badminton Rackets. Fives Balls. Hockey Sticks, Balls. Footballs and every sporting requisite. Factories: Woolwich, Tonbridge and Bolton. (Stand No. AB.17) [1]
1931 Gradidges was acquired by Slazenger Ltd[2]; it became part of the Slazenger, Sykes, Gradidge and Ayres group of companies.
1935 Gradidges entered into the field of golf club production and at the time their products were well regarded by golfers world-wide. Within a few years the brand and products had a strong following and quickly established itself on the world scene.
Their two most famous golfers were Reg Whitcombe, winner of the 1938 British Open (and runner up in 1937). The second, perhaps more famous, was Bobby Locke - four-time winner of the British Open and nine-time winner of the South African Open.
WWII The factory produced many hundreds of thousands of precision rifle stocks essential for the war effort, until it was destroyed in direct and heavy bombing by the Luftwaffe.
↑ 1929 British Industries Fair Page 70
↑ The Times, Feb 25, 1932
James Gradidge via email.
[1] Wikipedia
Retrieved from "https://gracesguide.co.uk/index.php?title=H._Gradidge_and_Sons&oldid=907401"
Town - Woolwich
Sports Goods and Games


text:
Q: how to sort the results of Collectors.groupedBy in same stream statement? Code:
public class Main {

public static void main(String[] args) {

    List<Book> books = new ArrayList<>();

    books = List.of(new Book("Aus dem All", "Horror", "Stephen King"),
            new Book("Evil", "Horror", "Stephen King"),
            new Book("See House", "Fantasy", "Anthony Marc"),
            new Book("Scream", "Thriller", "Larissa Vega"),
            new Book("Killer Hamster", "Horror", "Stephen King"),
            new Book("Who killed Ben?", "Thriller", "Stephen King"),
            new Book("The Hills have Eyes", "Horror", "Manfred Meyer"),
            new Book("Lost Love", "Drama", "Benedikt Hold"),
            new Book("Office Killer", "Horror", "Stephen King"));

    // group list of books by author

    Map<String, List<String>> collect = books.stream()
            .collect(Collectors.groupingBy(Book::getAuthor,
                     Collectors.mapping(Book::getTitle, Collectors.toList()))
    );

    System.out.println(collect);
}

}
collect result:
{Benedikt Hold=[Lost Love], Manfred Meyer=[The Hills have Eyes], Larissa Vega=[Scream], Anthony Marc=[See House], Stephen King=[Aus dem All, Evil, Killer Hamster, Who killed Ben?, Office Killer]}
I want the map key sorted by authors. "Anthony Marc" should be first then "Benedikt Hold" and so on..
i tried to sort the stream before the terminal operation collect with:
.sorted((b1,b2) -> b1.getAuthor().compareTo(b2.getAuthor()))
but the result is the same.
Have anyone a idea how i sort the results in my stream statement? (i dont want sort it after the stream. i want sort it IN my stream statement)

A: The map collected by groupingBy is not guaranteed to be a sorted map. It could be, for example a HashMap, which by its very nature has no order in its key value pairs.
You can specify the type of map you want groupingBy to collect into:
Collectors.groupingBy(Book::getAuthor,
                 TreeMap::new,
                 Collectors.mapping(Book::getTitle, Collectors.toList()))

The default constructor of TreeMap creates a TreeMap that orders the key value pairs by the natural order the keys, which seems to be the order you want here.


The tourist center Marko owns its own swimming pool. Relax after all-day activities in the swimming pool located within our tourist center, surrounded by greenery and beautiful vista.
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While adults are relaxing, kids will find the perfect place to play and have fun.Keep an eye on your youngest while they are having fun and playing safely.
Our children's playground is equipped with selected gadgets of innovative design and encourage children to play a creatively.


text:
The Next Great Paulie Fink (Paperback)
By Ali Benjamin
Village Books - Fairhaven
1 on hand, as of Jan 16 10:03am
(JMGF-)
Kobo eBook (April 15th, 2019): $7.99
Library Binding, Large Print (November 6th, 2019): $20.99
In this acclaimed novel by the author of the award-winning, bestselling The Thing About Jellyfish, being the new kid at school isn't easy, especially when you have to follow in the footsteps of a legendary classroom prankster.
When Caitlyn Breen begins her disorienting new life at Mitchell School--where the students take care of real live goats and study long-dead philosophers, and where there are only ten other students in the entire seventh grade--it seems like nobody can stop talking about some kid named Paulie Fink.
Depending on whom you ask, Paulie was either a hilarious class clown, a relentless troublemaker, a hapless klutz, or an evil genius. One thing's for sure, though: The kid was totally legendary. Now he's disappeared, and Caitlyn finds herself leading a reality-show-style competition to find the school's next great Paulie Fink. With each challenge, Caitlyn struggles to understand a person she never met...but it's what she discovers about herself that most surprises her.
Told in multiple voices, interviews, and documents,this funny, thought-provoking novel from the bestselling author of The Thing About Jellyfish is a memorable exploration of what makes a hero--and if anyone, or anything, is truly what it seems.
Ali Benjamin is a New York Times bestselling author and National Book Award Finalist for The Thing About Jellyfish, and the co-writer for HIV-positive teen Paige Rawl's coming-of-age memoir Positive as well as Tim Howard's national bestseller The Keeper. She lives near Williamstown, Massachusetts.
Praise for The Next Great Paulie Fink:
A ParentsMagazine 30 Best Kids' Books of 2019A LAPL Best Books of 2019A NYPL Best Books of 2019A KirkusReviews Best Children's Books of 2019
A PublishersWeekly Best Books of 2019
A PublishersWeekly Most Anticipated Children's Book of Spring 2019
An Amazon Best Book of the Month for April 2019
"A funny and fast-paced romp."
* "A story with massive heart... A book to make readers think, question, reach, laugh, and strive harder."
* "A witty, tender, and utterly engaging modern school story that draws on the wisdom of the ages."—School Library Journal, starred review
* "Genuinely original, the novel offers thoughtful perspectives on friendship, accepting change, and the many rewarding guises of storytelling, as well as a fully gratifying ending that the characters don't see coming."
—Publishers Weekly, starred review
* "A beautiful, powerful novel about embracing one's own great self, even--or especially--in middle school."—Shelf Awareness, starred review
"Benjamin strikes a nice balance of goofy, often physical comedy...with introspection...for a look at shifting middle-school identities and the strange chaos they bring."
—BCCB
"Takes the reader on a journey of self-discovery."—School Library Connection
"Sympathetic."
"Wise and funny."—The Wall Street Journal
"A middle school story to top all middle school stories."
"An inspirational story about finding your place in an unfamiliar community and learning that normal is not always better."—The Denver Post
"Laugh-out-loud funny."—Horn Book
"You'll love this new favorite about being the new kid at school, and dealing with bullies, and becoming something different."—Romper
Praise for The Thing About Jellyfish:A 2015 National Book Award Finalist
A New York Times BestsellerAn Indiebound BestsellerAn E.B. White Read-aloud Book Award FinalistAn Amazon Editor's Best Book of the 2015A 2015 GoodReads Choice Award FinalistAn Amazon Editors' Fall Favorite Children's BookA Booklist Top Ten First Novel of 2015A Publishers Weekly Best Book of 2015
*"A painful story smartly told, Benjamin's first solo novel has appeal well beyond a middle school audience."—Kirkus Reviews, starred review
*"Reminiscent of works by Jennifer L. Holm and Sharon Creech...a shining example of the highs and lows of early adolescence."—Publishers Weekly, starred review
*"Authentic and poignant...[a] superbly written, heartfelt novel."—School Library Journal, starred review
*"Clean, fluid writing that is highly accessible, yet rich with possibilities for discussion.... An uncommonly fine first novel."—Booklist, starred review
*"Just-right pacing, authentic voices and characters, beautifully crafted plot, and superb writing. Readers will find that this story lingers with them after the book is closed."—VOYA, starred review
"There are...a lot of children who might not only benefit from this book but also find themselves deeply moved by it."—New York Times Book Review
Publication Date: March 31st, 2020
Juvenile Fiction / Social Themes / New Experience
Juvenile Fiction / Social Themes / Friendship
Juvenile Fiction / Social Themes / Bullying
Juvenile Fiction / Social Themes / Adolescence & Coming of Age


Accomodation : The villa offers ten well appointed rooms, all with timber flooring, having attached bathrooms with running hot and cold water and showers. The emphasis is on cleanliness, special comfort, hospitality and the best of personalized service.The attractive rooms boast a host of facilities designed to make your stay as comfortable as possible.
Amenities : * Telephone with call transfer facilities to the rooms.
* Cable T.V. available in all the rooms round the clock.
* Provision for internet browsing and e-mail.
* Doctor on call .
* Car rental, local tours & treks.
* Safe deposit, Baby Sitters.
* Slideshow on local flora, fauna and culture on request.
* Hot water bag , Room heater and hair dryer on request.
Dining : A gracious dining room that opens out to the beautiful garden serving superb Indian, Continental and Chinese cuisine. Tibetan and local dishes are also available on request. Meals served are based on a day to day fixed menu and can be had either at the in house restaurant or outdoors on the lawn dining tables.
Address : Rhenock House (a Luxury Villa) Development Area, Gangtok � 737101, Sikkim India .


A learning experience like no other. The NPR internship program has a rich history, helping us discover nearly 10% of our current staff including Ari Shapiro, Audie Cornish, Guy Raz and many more.
From Day 1, interns at NPR are given real-world, hands-on responsibilities. Working alongside top professionals in the field, interns do meaningful work across a variety of departments at NPR. Find out how you can contribute your diverse talents to gain invaluable experience at the heart of a thriving multimedia organization.
Interns at NPR play a vital role in NPR's daily operations in almost every division of the organization – from NPR News and Music, to Communications and Engineering. Interns are also offered training opportunities. And here's the best part — you don't have to be an intern to start learning. You can access NPR Training's free website today.
We are looking for students and recent graduates who are smart and creative, good researchers and excellent writers. Interns need to both work well on diverse teams and thrive with individual assignments.
Candidates don't need to know everything about NPR or public radio, but it helps to be at least a little familiar. And it doesn't hurt to love NPR.
For more details on unique requirements for individual internship positions (cover letter, writing sample, design portfolio for example), see the internship descriptions for more details.
Interns are expected to work full time (40 hours per week). However, during winter/spring and fall semesters, part-time interns (at least 20 hours per week) will also be accommodated.
All interns are paid $13.25 per hour. The amount received during the internship is based on hours per week and the length of the internship period.
Candidates don't need to know everything about NPR or public radio, but it helps to be a least a little familiar. And it doesn't hurt to love NPR.
Interns may also receive academic credit. NPR does not offer transportation or housing assistance.
Internship positions are offered at our national headquarters in Washington, D.C.; NPR West in Culver City, CA; at the New York and Chicago Bureaus; and in Boston, MA. The location is listed in each of the internship descriptions.
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