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Expert Physician Assistant & Nurse Practitioner Insights on the Management of Plaque Psoriasis from Real-World Data : Episode 2
Evolution of Plaque Psoriasis Treatment Landscape
By Jayme M Heim, MSN, FNP-BC
Matthew T Reynolds, PA-C
Matthew T. Reynolds, PA-C, shares his treatment approach to plaque psoriasis based on the expanding therapeutic landscape.
EP: 1.The Pathogenesis of Plaque Psoriasis
EP: 2.Evolution of Plaque Psoriasis Treatment Landscape
EP: 3.Initiating Patient Conversations for the Management of Plaque Psoriasis
EP: 4.Multidisciplinary Care in the Management of Plaque Psoriasis
EP: 5.Role of IL-23 Inhibitors in the Treatment of Plaque Psoriasis
EP: 6.Administration and Dosing of IL-23 Inhibitors in Plaque Psoriasis
EP: 7.Safety and Efficacy of IL-23 Inhibitors for Plaque Psoriasis
EP: 8.Implications of Long-Term Data of IL-23 Inhibitors in Plaque Psoriasis
EP: 9.Using IL-23 Inhibitors in Patients Over 60 Years of Age With Plaque Psoriasis
EP: 10.Considerations When Approaching Treatment for Plaque Psoriasis
EP: 11.Practice Pearls for Advanced Practice Providers Managing Patients With Plaque Psoriasis
Jayme Heim, MSN, FNP-BC: Could you talk about the implications of the current expansion of the therapeutic landscape? Over the last years, especially the last 15 years, it's evolved quite a bit. There are medications available for treatment of plaque psoriasis that continue to evolve. We also have a problem identifying which of those medications to use sometimes with the patients with plaque psoriasis. Can you tell me more about your treatment approach for patients with plaque psoriasis?
Matthew T. Reynolds, PA-C: Absolutely. I believe wholeheartedly that this truly is the golden age of psoriasis treatment. We've come a long way in our options, in our armamentarium, with treating patients. I truly feel like we have a toolbox where we can walk into any patient at any time and have a variety of options to not only pick for the patient, but to have them help guide treatment decisions. We now have treatment options for children and adults that provide outstanding skin clearance rates and improve overall quality of life for our patients. With the expansion of the IL-17 [interleukin-17] and IL-23 [interleukin-23] classes, we now have a multitude of drugs to treat our patients to complete clearance, whereas a long time ago, we didn't have that as an option. PASI [psoriasis area and severity index] 75, PASI 50 were really good response rates not just a decade ago. The significance in these new treatments is that we can confidently assume that most of our patients are going to be at least 90% better in their skin score rates of their psoriasis and across both classes of drugs, the IL-17 and IL-23 classes. Secondly, these drugs are becoming easier to prescribe due to a lack of overall adverse events and insurance access. Upper respiratory tract infections, tinea infections, MACE [major adverse cardiovascular] events, malignancies, inflammatory bowel disease rates are very, very low across both classes of drugs. Lastly, with the widespread awareness of these medications and their rapid expansion into the dermatology space, more and more prescribers are now using them, which is great for patients and then great for the overall health care system. We now know that biologic prescription rates are increasing faster than they ever have in previous years, and these biologic agents are being written more and more by advanced practice providers like nurse practitioners and physician assistants. Now, certainly every APP doesn't only see plaque psoriasis patients. We see many types of general dermatology patients. But often the APP is now assuming that role of identifying appropriate plaque psoriasis patients for biologic therapy and managing their disease.
Jayme Heim, MSN, FNP-BC: Thank you, Matt. In your opinion, if as an APP you're working in an academic setting or a private practice setting, or even a community-type setting, what would be the differences within practice in dermatology?
Matthew T. Reynolds, PA-C: I meet a lot of people from around the country who practice in 1 or both settings. I think the differences between these 2 settings specifically are fairly stark. I know in my area in central Arkansas that the academic center has very restricted rules on allowing pharmaceutical industry access to the dermatology center or to the residents or the PAs [physician assistants], PNs [practical nurses] or students. Therefore, education and access to vital information for writing prescriptions may favor older therapies for patients with more insurance or no insurance as a way of saving costs in the academic setting. In the community setting, we would most likely provide those patients with newer therapies or samples or access to, say, a clinical trial. Those are becoming more and more popular in private setting. An academic setting is also more likely to use infusible products due to the access and proximity to [an] infusion center. There are drugs that are specifically infused in psoriasis or provided better in an infusion-type setting. A patient would most likely receive, for instance, adalimumab in a community setting, whereas at an academic setting they may receive certolizumab so that the academic center may capture additional reimbursement for that medication. The same is true of the IL-23 class and tildrakizumab. Now as an APP, there's an extreme sense of flexibility in working in the community setting that we seemingly have more access to our pharmaceutical reps, our sales reps, our MSLs [medical science liaison], more access to samples, and a little bit more prescription authority versus, say, an academic setting with harsher rules on access to drugs, access to filling out prior authorizations for drugs, and things of that nature.
Study Suggests Efficacy of Guselkumab in Psoriasis Patients with Inadequate Ustekinumab Response
How Determi-Nation Promotes Diversity in Psoriasis Research and Treatment
Positive Association Observed Between Anxiety Disorders and Psoriasis
Rebecca Kazin, MD: Cosmetic Dermatology Trends, Technologies, and Practices
April 23rd 2021
Psoriasis Patients and Their Adherence to Topical Treatments
Study Indicates Deucravacitinib Superior to Apremilast, Placebo for Plaque Psoriasis Patients
January 3rd 2023


Cholesterol absorption inhibitor and statin combinations are compounds that prevent cholesterol from rising in the small intestine and the circulatory system. Exercise and eating right are always important, but if that's not enough to bring down your cholesterol, taking these medications will help. Cholesterol absorption inhibitor and statin combinations are a mixture of medicines taken together when taking just one type of medications isn't helping. They aid each other in the process of managing certain conditions. Using statins alone sometimes isn't enough. Cholesterol absorption inhibitors are sometimes also not enough. Mixing cholesterol absorption inhibitors and statin combinations are extremely helpful when fighting high cholesterol.
Drugs that are classified as cholesterol absorption inhibitor and statin combinations are listed below.
This drug helps people that are not affected by statins by themselves. Statins are drugs that help lower cholesterol. Unfortunately, they don't always get the job done by themselves. That's why statins are often mixed with another type of drug. Cholesterol absorption inhibitors will help control high cholesterol and keep it down. That is why these two are often combined.These inhibitors also lower the total cholesterol and LDL. LDL is low-density lipoprotein. Lipoproteins transport fat throughout the body. LDLs can contribute to blockage in the artery. Artery blockage puts you at risk for heart disease which can lead to heart attacks. Cholesterol absorption inhibitor and statin combinations can help lower the risk of these adverse side effects.
You should always ask your doctor about the side effects of the specific medication you've been prescribed. Common side effects occur from taking this drug, but are often known to go away with prolonged usage.
Like any other drug, cholesterol absorption inhibitor and statin combinations may interact with other drugs. Below you will find drugs that may interact with cholesterol absorption inhibitor and statin combinations. Note that not all interactions are listed here.


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Home » US NEWS » Child with Garrett Hedlund: Emma Roberts shows her first baby photo
Child with Garrett Hedlund: Emma Roberts shows her first baby photo
Wednesday January 13th 2021
Child with Garrett Hedlund
Emma Roberts shows first baby photo
Emma Roberts and fellow actor Garrett Hedlund have been a couple since 2019. In the summer of last year, the 29-year-old made public that she was expecting her first baby. That is now born. Now Roberts is giving her fans a look at the youngsters for the first time.
At the end of August, Emma Roberts announced on Instagram that she was expecting her first child. The baby's father is Garrett Hedlund, with whom the American Horror Story actress has been dating since 2019. At the time, she posted a photo of herself with a baby bump and also the first photo of her father. Now there is also the first photo of the offspring on Instagram.
In the picture you can see Roberts in an orange dress and matching shoes sitting on a striped outdoor sofa while she lovingly holds her newborn son in her arms. "Thank you 2020 for doing something right," she wrote about the picture where she is holding her little boy in her arms. Roberts also revealed the baby's full name: "Our bright light Rhodes Robert Hedlund", wrote Julia Roberts' niece.
Hedlund participates in anti-drug program
Recently, the child's father made less positive headlines. Garrett Hedlund was arrested for drink-driving in February last year and was only released on bail of $ 100,000. He was then charged on two counts with "DUI" (short for "Driving under the influence", ie driving under the influence of alcohol or drugs). According to the US celebrity portal "Page Six", he was sentenced in November to a 36-month suspended sentence and three days of community service. Hedlund must also take part in a nine-month anti-drug program. According to a spokesman, the 35-year-old did that directly.
The first rumors about a relationship between Emma Roberts and Hedlund, known from "Tron: Legacy" among others, came up less than two years ago. In early 2019, Roberts broke up with former co-star Evan Peters, whom she met while filming in 2012. She was previously with Alex Pettyfer. Hedlund was in a relationship with Kirsten Dunst from 2012 to 2016.

redpajama_set_name: RedPajamaCommonCrawl


Mid nineteenth century gilt bronze and enamel taper stick.
This fine quality gilt bronze taper stick was made in France in the middle of the nineteenth century. Its function was that of a desk accessory, holding a taper or small candle for melting sealing wax for letters. The beautifully modelled and cast gilt bronze cherub sits on an onyx base which in turn is mounted on a gilt bronze stand with champleve enamel decoration. The prduction of chamleve enamel involves carving the pattern out of the item to be decorated, then filling the resulting recesses with coloured enamel.
This superb gilt bronze taper stick measures 9.5cm wide, 7.3cm deep and stands 8cm high. (Measurements approximate). It is in excellent condition, showing wear appropriate to its age. It has no damage and no restoration.


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Чемпионат Украины по фигурному катанию на коньках 2006 года () — украинский национальный чемпионат по фигурному катанию сезона 2005—2006.

Спортсмены соревновались в категориях мужское и женское одиночное катание, парное катание и танцы на льду. Чемпионат прошёл в Киеве с 23 по 25 декабря 2005 года.

Результаты

Мужчины

Женщины

Пары

Танцы

Ссылки
 Результаты чемпионата 2006 на сайте planete-patinage.com

2006
2005 год в фигурном катании
Украина
Спортивные соревнования в Киеве

redpajama_set_name: RedPajamaWikipedia


Be at the BRITS 2015 with Mastercard!
You could be at the BRIT Awards 2015 with MasterCard at the O2 in London on Wednesday 25th February!
We've got a pair of balcony tickets to the show, free rail travel and overnight accomodation to give away, and it could be you winning this amazing prize! Just click on the link below to find out more.


The Kate Show currently sits on the iTunes Business Top 200 Podcasts chart and averages over 3K subscribers / listeners per month.
Do you serve interior designers, home stagers or window treatment professionals? Get your services and products in front of Socialite's loyal audience of home professionals. Apply below for a spot in Sociailte's exclusive list of podcast sponsors and preferred vendors.
Includes listing in Socialite's membership platform, Vault, which serves home industry professionals in the United States, United Kingdom, Australia, and Canada.
Includes a 60 second ad spot on two podcast episodes per month and tagging on social media when those episodes are shared.
Includes both Preferred Vendor & Basic Sponsor features with your choice of ad placement (intro, mid-show, or end).
Thank you! We will review your application and be in touch.


Since starting our in-seat Embedded Device Exploitation class, we've been getting queries about offering the class online.
Well, good news: it's coming! But, we need to gauge interest before deciding to go all-in, so if you want to see EDE offered online, go to www.edetraining.com and submit your email address. We'll notify you as soon as online registration is available!


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Tiffany Evans Drops New Song, 'Money Ain't Everything'
by Singersroom June 19, 2018
Tiffany Evans uses her own experiences to prove a valid point, "Money Ain't Everything."
On her latest release, the R&B powerhouse inspires others to take heed of the intangible moments in life, singing, "I don't know what you've been told; Nothing last, nothing last forever," she sings.
"I wrote and recorded this song four years ago when I was in a really vulnerable space in my life," says Evans. "I remember being fed up with the world being so materialistic to the point where we hurt others just to get what we want."
She continues, "I just wanted to spread a message that MONEY AIN'T EVERYTHING. It doesn't guarantee life or happiness or true love. Inner peace, compassion for others and your purpose is really all that matters in the end. In the wake of what's happening in the world right now, I hope this song speaks to every soul out there that is seeking peace."
"Money Ain't Everything" is not an official single, but Evans plans to release a new project later this year. It will be her first project since 2015's All Me, which has over 5 million streams worldwide.
TaggedTiffany Evans
Veteran R&B Trio Next Unveil Sexy Video For 'I Want It'
Stream Christina Aguilera's New Album, 'Liberation'
Delilah – Never Be Another
Mishon Offers His Version of 'Hotline Bling'
Chris Brown – Yo (Excuse Me Miss)
Shanice – Another Lonely Day In California
Melissa Jay – KTN (Kill That Ni**a)
Mateo Amarei – First Car Feat. Ricquo Miguel Jones


Bento is a Japanese word for home packed meal.
My daughter is turning 2 next month and I want to prepare something light and cute for her Sunday school's friends. She likes Elmo so much but I had no luck with Elmo bento. I want the Bento to be an individual serving, or at least in a box so I don't have to deal wit serving and cleaning.


Arctic Silver Metallic Cabriolet with Black Full Leather and Black Top. Great colours on this 2004 Turbo Charged car! Factory options include Tiptronic S, Metallic Paint, Sport Techno Wheels, Stainless Steel Exhaust Pipes, Metal Doorsills with Model Insignia, Aluminum Shifter and Handbrake, Heated Seats, Sport Seats, Aluminum Instrument Dials, BOSE High End Sound System, Navigation for PCM and Three Spoke Leather Steering Wheel. This Canadian car is also outfitted with an X50 Turbo Power Kit, factory installed engine enhancement performance package that increases horsepower to 450 bhp. This package includes modifications to the turbocharger, air intake cooler, electronic control unit, exhaust system, as well as a strengthened transmission. The X50 package is only available as an option from the Porsche factory.
Previously sold and serviced by the Porsche lovers here at Weissach, this powerful and sport cabriolet is ready for you today!


There are many nail art and ideas about nail designs. However, out of many, acrylic nail ideas we are going to bring here to you.
Moreover, nail art designs and colors are such as, acrylic nails, coffin nails, almond nails, stiletto nails and short nails also long nails for women satisfaction for their nail fashion.
By the way, 15 Acrylic Nail Ideas here explaining with images in many colors, in many designs to bring the best for your pick for any season, any occasion.
'Simple is the best.' And, this acrylic nail is very simple and natural in look. In case, you like the simple ways of style, then for your nails this can be just perfect.
By the way, plain orange color on nails with butterfly can be cool. As you are looking for nail ideas, here, this design is just nice for you.
Floral nail art and also purple to give your nails a gorgeous look. However, by applying combination of colors, you can bring the best art design on your nails.
Variation of colors on nails, also in gold color. You can choose that suitable for you as you nail style.
Moreover, this amazing art on nails, is really looking fantastic.
And, shade of soft pink is glittering on nails as to catch eyes. Gorgeous!
Have a look at this picture of nails to find out the secret of nail art. However, glossy and glittering nails are looking great.
As symbol of purity white is always preferable for any kind of fashion, style. And, here for acrylic nails ideas white and rose is apply on nails. And, the nail art is looking great.
Meanwhile, navy blue is for nails. Moreover, bright navy blue on nails looks nice.
For example, here in black and white nails are enough attractive and looking lovely, as well. You are going to feel happy.
Also, black and pink acrylic can make your nails gorgeous as the picture here. And, you will feel comfort with your outfits in any color.
And, here you are with the idea of long coffin nail shape in vintage soft raspberry pink gel polish, which is definitely to make nails beautiful.
However, while you are looking for ideas for acrylic nails, here is another one in green and gold glitter color. And, it will look good on short or long nails anyway.
Obviously, this nail art idea is really fantastic in black on your nails. Moreover, plain black or in mix design with black, you can give your nail a gorgeous look.
At the end, here is another stunning pretty sparkling pastels and pink flowers on nails for you to inspire as well. However, have a look to find in details the art on nails. Certainly, looks gorgeous.


As you age, you think you are in good shape. You've completed plans for your retirement funds and finalized your will. If you have been divorced, however, you may want to think again. You may have overlooked ways of how your former spouse can inherit from you!
Wills, for instance, don't have the final say about who gets the assets in your IRA or 401k. Lack of oversight regarding beneficiaries can result in your former spouse inheriting that money. In addition there are rules and laws which can also allow a former spouse to draw Social Security based on your earnings.
As changes occur in life, people often overlook changing beneficiaries on important accounts. Steps to do this may vary depending on changing employers and rules. For a current employer, simply request a change-of- beneficiary form from the company's human resources department.
To change the beneficiary on a 401k also requires a visit to the human resources department. To leave benefits to someone besides a spouse, you must present a paper signed by the spouse showing agreement to give up their beneficiary claim.
401ks from previous employers need to be rolled over into an IRA with proper beneficiary forms.
All documents should have secondary beneficiaries named in case of death of the primary beneficiary first.
Federal laws also allow former spouses certain benefits from your Social Security and Military Retirement.
These areas involving financial planning are just some of the reasons it is a good idea to retain a good attorney for assistance. They understand the nuances of the laws regarding overall estate planning including wills, probate and updating beneficiaries. They know how to avoid disruption of your estate plans and reduce estate taxes.
The potential complexities of estate planning don't have to create anxiety for you. We can provide the knowledge, skills and help you need to assure everything is in order. Be sure to contact us soon for an appointment for a consultation.
Special Needs Planning - When Should You Plan For Guardianship?
What is the Burden of Proof in Trust and Will Contests?


The Indonesian Trading Company is based on the concept of responsible business and fair trade.
We do our utmost to ensure that within the company we adhere to tenets of equitable trade and environmental responsibility.
At Indotraders, we believe that the best way to help ourselves and our company is to help everyone who works with us. In light of this philosophy, we ensure that everyone is paid a fair price for their work – from our craftsmen to our office staff. We do not believe in "squeezing" anyone dry to maximize our own profits.
Our staff are paid good wages, provided with child support, and provided with interest free loans (when required) to avoid the high interest rates charged by local banks. As a result, many of our staff have been able to become home and property owners.
At Indotraders, we believe in equality. Salaries are gender-blind and women make up over 85% of the workforce in our office and warehouse.
The tenets of fair trade, which we strive to adhere to, demand a safe and healthy working environment. At Indotraders, we ensure that our craftsmen do not use child labour in the production of their goods and we do not hire children to work in our office or warehouse. The health and wellbeing of our staff is of utmost importance to us and all spaces owned by Indotraders uphold rigorous safety standards. Furthermore, all our staff and their children are fully covered for medical issues.
To go a step further, we are determined to provide for the future of our staff and their children. All costs associated with the education of their children (school fees, uniforms, books, academic excursions, private tutoring) are covered by the company.
Finally, in line with the principles of fair trade, Indotraders endeavours to do its best for the environment. All packing materials are recycled, and all our staff have been educated about responsible waste management and recycling.
If you have any questions about how The Indonesia Trading Company upholds particular principles or functions as a whole, please feel free to contact us with your questions. We understand that you will want to ensure that as your supplier, we are upholding the ideals of responsible business.


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Instruction for use: Citol
Dosage form: coated tablets
Active substance: Citalopram*
N06AB04 Citalopram
Pharmacological groups:
The nosological classification (ICD-10)
F32 Depressive episode: Adynamic subdepression; Astheno-adynamic subdepressive states; Asthenoadressive disorder; Astheno-depressive disorder; Asthenodepressive state; Astheno-depressive state; Major Depressive Disorder; Vyaloapatichesky depression with retardation; Double Depression; Depressive pseudodement; Depressive illness; Depressive mood disorder; Depressive disorder; Depressive mood disorder; Depressive state; Depressive disorders; Depressive syndrome; Depressive syndrome larviated; Depressive syndrome in psychoses; Depressed masks; Depression; Depression Depletion; Depression with the phenomena of inhibition within the framework of cyclothymia; Depression is smiling; Involutional depression; Involutionary melancholy; Involutional depression; Manic-depressive disorder; Masked Depression; Melancholic Attack; Neurotic depression; Neurotic depression; Shallow Depression; Organic depression; Organic depressive syndrome; Simple depression; Simple melancholic syndrome; Psychogenic depression; Reactive depression; Reactive depression with moderate psychopathological symptoms; Reactive depressive states; Reactive depression; Recurrent depression; Seasonal depressive syndrome; Severostatic depression; Senile Depression; Symptomatic Depression; Somatogenic depression; Cyclotymic depression; Exogenous depression; Endogenous depression; Endogenous Depressive Conditions; Endogenous Depression; Endogenous depressive syndrome
Composition and release form
Tablets, coated with a coating.
citalopram 20 mg; 40 mg
auxiliary substances: corn starch; lactose; PVP; avicel PH200; magnesium stearate; hydroxypropylmethylcellulose; polyethylene glycol 40, titanium dioxide
in the package contour cell 28 pcs .; in a pack of cardboard 1 (Table 20 and 40 mg) or 2 (Table 20 mg) packaging.
Description of dosage form
White elliptical tablet-shaped tablets, with the logo "Ai" - on one side and the dividing risk - on the other.
Antidepressant, from the group of selective serotonin reuptake inhibitors (SSRIs).
Pharmachologic effect
Pharmacological action - antidepressant.
Has a strong ability to inhibit the reuptake of serotonin, has no or has a very weak ability to bind to a variety of receptors, including histamine, muscarinic and adrenoreceptors. To a very small extent inhibits cytochrome P450 2D6 and, therefore, does not interact with drugs metabolized by this enzyme. Thus, side effects and toxic effects are manifested to a much lesser degree.
The antidepressant effect usually develops after 2-4 weeks of treatment.
Has no effect on the conduction system of the heart and blood pressure, on hematologic indices, liver and kidney function, does not cause an increase in body weight.
When administered, the bioavailability of citalopram is about 80% and is virtually independent of food intake. Cmax in plasma is achieved 2-4 hours after administration. Binding to plasma proteins is below 80%. The plasma is present unchanged. At doses of 10-60 mg / day pharmacokinetic parameters have a linear dependence. The volume of distribution is 12 l / kg. Css with a daily one-time reception is established after 7-14 days. Penetrates into breast milk.
Metabolized by demethylation, deamination and oxidation involving cytochrome P450 (isozymes CYP3A4 and CYP2C19) with the formation of less pharmacologically active metabolites.
T1 / 2 of the drug is 1.5 days. Excretion is performed by the kidneys and with feces.
Indication for the Citol
Depressive disorders of various etiologies.
hypersensitivity;
simultaneous administration with MAO inhibitors (including the period within 14 days after their cancellation), sumatriptan and other serotonergic drugs;
children's age (efficacy and safety of use not established).
Carefully:
hepatic and / or renal insufficiency;
convulsive seizures (including in the anamnesis);
pregnancy;
lactation period;
elderly age.
The undesirable effects of Citol ® have a transient character and are poorly expressed. As a rule, they are observed during the first 1-2 weeks of treatment and usually significantly weaken as the patients improve. In very rare cases, convulsions were observed.
Side effects can be systematized as follows.
From the cardiovascular system: often - bradycardia, postural hypotension, arterial hypotension; rarely - arterial hypertension, tachycardia, puffiness, angina, extrasystole, arrhythmia, heart failure, myocardial infarction; in exceptional cases - transient ischemic attacks, phlebitis.
From the nervous system: rarely - asthenia, excessive fatigue, drowsiness or insomnia, anxiety, tremor, impaired concentration, agitation, amnesia, apathy, extrapyramidal effects, mood reduction, aggressive behavior, hallucinations, depersonalization, confusion, emotional lability, euphoria , manic disorders, panic behavior, suicidal attempts, paranoid reaction, psychosis, serotonin syndrome (agitation, confusion, diarrhea, hyperthermia, hyperreflexia, ataxia, tremor, increased sweating, agitation, uncontrolled behavior), rarely - drug dependence, catatonic reactions.
On the part of the digestive tract: rarely - dry mouth, nausea, vomiting, hypersalivation, flatulence, diarrhea, abdominal pain, anorexia, gastritis, gastroenteritis, stomatitis, hemorrhoids, dysphagia, gingivitis, esophagitis, an increase in "liver" transaminases and alkaline phosphatase; in exceptional cases - colitis, stomach ulcer, cholecystitis, duodenal ulcer, gastroesophageal reflux, glossitis, jaundice, diverticulitis, hiccough.
From the hemopoietic system: thrombocytopenia, purpura, bleeding disorders, bleeding.
From the musculoskeletal system: rarely - arthritis, muscle weakness; in exceptional cases - bursitis, osteoporosis.
From the endocrine system: in exceptional cases - hypothyroidism, gynecomastia.
From the senses: rarely - mydriasis, paresis of accommodation, a taste disorder.
On the part of the reproductive system: often - violation of sexual function (violation of ejaculation, decreased libido, impotence, menstrual irregularities); galactorrhea, breast augmentation, vaginal bleeding.
On the part of the respiratory system: often - cough; rarely - bronchitis, rhinitis; sinusitis; shortness of breath, pneumonia; in exceptional cases - asthma, laryngitis, bronchospasm.
From the genitourinary system: often - polyuria, dysuria; in exceptional cases - hematuria, oliguria, pyelonephritis, kidney pain.
Skin reactions: often - skin rash, hair loss, itching; rarely - increased reaction to light, hives, acne, eczema, alopecia, dermatitis, psoriasis epidermal necrolysis, in exceptional cases - hypertrichosis, decreased sweating, keratitis, cellulitis, itching of the anus.
Other: rarely - mastodynia, hyponatremia, yawning, gnashing of teeth, increase or decrease in body weight, dyspnea.
If side effects develop, immediately consult a doctor.
Strengthens the effect of sumatriptan and other serotonergic drugs. Does not affect the effects of ethanol, drugs Li +, benzodiazepines, antipsychotic drugs (neuroleptics), narcotic analgesics, beta-blockers, phenothiazines, tricyclic antidepressants, antihistamines and hypotensive drugs.
To an insignificant degree inhibits cytochrome CYP2D6, and therefore weakly interacts with drugs metabolized with its participation.
With simultaneous administration with MAO inhibitors, the development of hypertensive crisis (serotonin syndrome) is possible.
Cimetidine increases the concentration in the blood and increases the effect of citalopram. At simultaneous appointment with warfarin PV increases by 5%.
Dosing and Administration
Inside, 1 time per day, regardless of meals, at any time of the day. The initial dose is 20 mg / day, if necessary, increase the dose. The maximum daily dose is 60 mg.
The recommended daily dose for the elderly is 20 mg. Depending on the individual reaction and severity of depression, the dose can be increased to a maximum of 40 mg / day.
In case of liver failure, the drug intake should be limited to the minimum recommended doses. With a mild to moderate degree of chronic renal failure, correction of the dosing regimen is not required.
Symptoms: dizziness, drowsiness, dysarthria, sinus tachycardia, nodal rhythm on the ECG, prolongation of the QT interval, pirouette arrhythmia, ventricular arrhythmia, increased sweating, vomiting, cyanosis, hyperventilation of the lungs, tremor, amnesia, confusion, rhabdomyolysis, seizures, coma.
Treatment: gastric lavage, symptomatic and maintenance therapy; there is no specific antidote.
There is very little clinical experience with the use of Citol® in the conduct of electroconvulsive therapy.
When developing manic state the drug should be canceled.
Treatment with MAO inhibitors can be initiated no earlier than 7 days after stopping citalopram.
Care should be taken when prescribing during breastfeeding because of the risk of drowsiness in infants, a reduction in the sucking reflex, and weight loss.
In elderly patients, the area under the concentration / time curve (AUC) and T1 / 2 citalopram increases, which requires a reduction in its dose.
During the treatment period, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions, as well as when taking alcohol.
Storage conditions for Citol
At a temperature of no higher than 25 ° C.
Shelf life of Citol
Do not use after the expiry date printed on the package.
Instruction for use: Citalopram
Instruction for use: Coaxil
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Retail's role in a plastic-free future
Catherine Conway, founder of Unpackaged, explains how independent retailers can lead the charge on sustainable packaging
Sustainability has been a key word of 2020, and the food and drink sector has come leaps and bounds in past few years when it comes to single-use packaging – but there are still more changes to be made, according to Catherine Conway, founder of Unpackaged – an innovative business offering retailers of all sizes refill and reuse formats.
"So much of it is about knowledge," Catherine says. "I'm so amazed when I go to packaging trade shows at the 98% conventional plastic packaging and just 2% innovative options. A Plastic Planet has their stand where they show off of these different materials and applications, and I'm astounded that packaging designers don't think about how their packaging is going to be disposed of when it's designed."
Consumers appear to be the ones driving the charge. "The consumers of tomorrow don't want single use packaging, and they're going to be both the consumers and employees of the future," she explains. "We have a world-class packaging industry, and while I'm often positioned in opposition to packaging manufacturers I just want them to shift their focus from designing single use packaging to designing durable, reusable, refillable."
So what can retailers do to spur change in the industry? Unpackaged has worked with independents and multiples alike – from Planet Organic to Waitrose and Marks & Spencer – to help food stores implement reuse and refill systems as a way of solving the single-use packaging crisis.
But these solutions might not be right for every business. "Retailers first have to consider who their customer base is; if a shop is selling nothing but ready meals, there's no point putting in bulk aisles of arborio rice because that's not what their customers are buying or where the impact lies," Catherine says.
And while 80% of the market is still in-store, there is also now a home delivery window that offers new opportunities for reuse and refill. "There's a lovely mobile market stall/truck in Hackney that goes round people's streets and they can refill their products," Catherine says. Indeed, as the zero waste movement has grown, the industry has seen a growing fleet of mobile zero-waste shops. "It's not just the big guns that can do home delivery."
Even taking a critical eye to your product offering could help you reduce your plastic footprint. Catherine explains: "Because of what happened with Covid, supplies drying up and space needing to be reallocated to other things, retailers have rationalised their range – in doing so avoiding unnecessary packaging in their stores."
Independent food retailers, many of whom have seen a boost in business since the pandemic hit, also have an educational role to play. "We now need to help NGO campaigners to be championing reuse, trying to educate people on the reuse and refill model. There's a great swathe of customers who can make this change and should be doing so," Catherine explains. "We need a big shift, in marketing, operations, in-store experience – it's a long term project, and we should all be doing something."
Looking for more ways to boost your eco credentials? Download your free copy of A Sustainable Future 2020, produced in partnership with Speciality & Fine Food Fair for more exclusive insight from sustainability pioneers.
Anthony Davison, Big Barn: "People are realising that local is the right way to go"
Anthony Davison, founder of Big Barn explains the benefits of sourcing locally – and why the industry needs more local advocates
What a Brexit stockpiling crisis could mean for indies
Independent food retailers pulled ahead during Covid panic buying – can they do it again if Brexit causes more stockpiling?
UK organic exports get the green light
The European Union's decision to recognise Britain's organic products comes as a "huge relief" to the sector – but over the long term, questions still remain


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Brewing some mid-day coffee in the Colorado Rockies in November on a chilly and rain-soaked day.
This is a multi-part series about my trail-tested backpacking stove systems. Start reading with the Introduction, or view all posts in the series.
While preparing for a backpacking trip in the Colorado Rockies this coming weekend (early-November), I had to consider the appropriateness of my ultralight alcohol stove and my powerful remote canister stove systems. I concluded that both would be functional, but that with an extra $50 purchase I could have a perfectly optimized kit.
Not deterred by the relatively high fuel expense, relative to alcohol and liquid fuel (e.g. white gas).
For some backpackers, Fast & Light will be perfect year-round, or at least outside of the winter months. But for me, I take it along only on solo trips in the shoulder seasons when large volumes of hot water will be desired, to help keep me comfortable despite brisk daytime conditions, long nights, sub-freezing overnight lows, and perhaps only low or moderate physical exertion. Imagine making each day a hot breakfast and morning coffee, mid-day coffee or tea, hot dinner, and hot nighttime tea.
For such extensive cooking I could use my alcohol stove. But its slow boil times would frustrate me, and its low fuel efficiency would partially offset its feathery base weight. Alternatively, I could use my remote canister stove. It would be faster and more fuel efficient, but unnecessarily heavy and overkill (because I wouldn't fully utilize its sturdiness or its cold-weather performance).
This setup has sufficient firepower to melt snow, but I would not make a habit of it. Other stoves are better suited for this application, notably my winter backpacking stove system.
My stove system for solo backpacking trips in the shoulder seasons, when I'm willing to carry a few extra ounces so that I can quickly heat up large amounts of water. With a larger pot and an additional eating container, mug, and utensil, this system would be suitable for couples, too.
My complete kit is below. It need not be replicated exactly, but it's a good starting point.
Save weight by using the 3.9-oz fuel canister (3.5 oz empty, 1.6-oz reduction) and a plastic or metal mug (or none at all, up to a 3.3-oz reduction). And drop the cost by purchasing a $2 Starbucks mug, and a stove and pot made of heavier aluminum and/or steel, not titanium.
To use this setup as a two-person stove, make these changes.
Use a larger pot, at least a 1.3L if not a 2L. Note my discussion below about heavy pots and stove strength.
Bring an eating container (my recommendation: a 1L grease pot for $10), plus an extra hot drink container and utensil.
The stove is the most interesting item in this kit, but let me quickly address some of the other categories.
My pot is the most expensive item in this kit, at $60. The reason: I have used the Evernew Titanium Ultralight 900 ml for over a decade (I'm on my third, I think), and I already own it.
A wide-and-short pot like the Evernew will be more fuel-efficient than a deep pot, although it's not a deal-breaker like it can be for the Super Cat Stove. The ability to "nest" a canister into the pot is not an advantage, IMO, as it simply transfers dirt into the pot. Instead, fill the pot with extra food, and let the canister float inside your pack.
When I pack this stove, the conditions are often such that I enjoy a hot drink to go. With its screw-top lid, the Nalgene allows this. Also, with its wide-mouth opening, pouring hot liquids into it is relatively easy and safe.
If you don't need a hot drink to go, then use a $2 reusable plastic cup from Startucks or spend substantially more on the Snow Peak Double Wall 450 or similar.
The SupaLite and Snow Peak LiteMax are both made by Kovea and are nearly identical. The biggest difference is that the SupaLite retails for $50; the Litemax, for $60. A penny saved is a penny earned.
The Supalite should not be paired with large pots. I will primarily use it with the 900 ml Evernew, and on occasion maybe a two-liter MSR. But if I were regularly using a 2L+ pot, I would use a stove like the MSR Pocket Rocket or Snow Peak Gigapower (or Gigapower Auto) that is more sturdily designed, in terms of its materials and architecture. I could easily argue that the Supalite/Litemax is "stupid light" because of this issue.
I was indifferent to this feature, which adds weight and expense, and which is redundant with the Bic lighter that I always carry on backpacking trips (for fire-starting, if for no other reason).
The Soto OD-1R Micro interested me because it is the lightest regulated stove and therefore will perform better in cold temperatures than non-regulated upright canister stoves. But I concluded that this feature was unimportant to me: I plan to use the Supalite to heat up a maximum of 1.5 liters of water at a time in temperatures ranging from 10's to 50's. That will take less than 10 minutes.
For cold ambient temperatures to have a significant effect on the stove performance, the stove run time would have to be longer. In very cold temperatures, I can bring the canister up to body temperature by keeping it in my jacket or sleeping bag prior to use.
The superior fuel efficiency of integrated stoves does not offset the higher base weight unless the stove is used extensively, like on long trips and by large groups. Even then, it's a marginal difference. The true advantage of an integrated stove is its convenience.
The Dirtbag and Cadillac are lighter, with most of the weight-savings being due to the stove and the fuel bottle/canister. Both burn alcohol, which is more widely available than gas canisters but has less firepower.
So, if you are willing to carry a few extra ounces in exchange for faster boiling times, and if you can reliably purchase replacement canisters, then opt for Fast & Light. If you prioritize weight above speed, and/or if replacement canisters will be difficult to find, then go with alcohol.
Hot & Heavy is more suitable for larger pots (e.g. one- or two-gallon sized): its design is more stable and its pot supports are stronger. In contrast, upright stoves are scarily top-heavy if paired with large pots, and ultralight upright stoves like the Kovea Supalite may not have the long-term strength to support the weight. Finally, Hot & Heavy shares the same core components as my winter backpacking stove.
To use one- or two-gallon pots, which are too heavy and tip-prone for upright canister stoves.
Questions or feedback? Please leave a comment.
Looks like a great system and very similar to one that I use. All weights are in ounces, fuel bottle not included as the size varies depending on the trip.
What do you use for a windscreen?
A small piece of aluminum that hangs off the bottom of the pot that covers about 75% of the circumference. It's a design that I'm still not 100% sure on yet, so far it seems to help as that BRS is a bit susceptible to wind. The windscreen hangs down to just below the burner head.
I don't seem to have as much of a wind issue with my Litemax though, which was the stove I was using prior to the BRS. The fiddle factor to save 1/2 an ounce is still up in the air as far as if it's worth it. But at the cost of the BRS I just had to have one to try out.
I cut it and roll it with a rolling pin to flatten it. Then I fold the edges and roll them so it's not sharp. It measures about 9″x14″. I have it folded in thirds and it fits inside my freezer bag cozy. And it weighs 23 grams. It fits around my stove and pot and leaves one side open, so the canister doesn't overheat. And I find that it helps boil faster because it directs the heat up the side of the pot.
I use my BRS without a windscreen and manage to keep it out of the wind and running efficiently by choosing a protected place to cook. A protected spot behind a rock or log is nearly ubiquitous in backcountry settings, and pretty much required for any type of stove short of a Coleman two-burner.
Upright canister stoves are very susceptible to wind. Without a windscreen, how do you shield the stove in windy conditions?
In the photos you have the pot handles removed. I do the same in warm conditions but given that you're pouring large amounts of boiling water into a nalgene, is that a bit "stupid light"?
1. I take great pains to avoid windy campsites. In the event that it cannot be avoided, or I care not to avoid it, I can bring the stove inside my shelter (which, importantly, I would keep well ventilated) or I can shield it with my backpack or rocks.
I also went for this pot set which again is cheaper but heavier and has more than some would want to carry along. I personally like having the little "tea pot" along with a traditional pot so I can have extra water while I'm eating my meal.
Going uber light has it's place but I think most people are willing to carry extra ounces for a bit of ease and comfort.
In addition to being 1/4 the price, that remote canister stove gives you much more stability than an upright. That's what I love about the Windpro — I never worry about putting a huge pot atop it. The Windpro has the option of a liquid feed, however, which makes it a viable winter stove. This Dpower stove would not be.
Hilariously, the top link now sends you to anti-snore strips.
I'd say just search for Dpower stove for future reference.
It works fine with my Evernew pot for morning hot water chores. It is stupid small, light, and seems pretty efficient. After weeks of use I have no complaints.
This is very similar to what I took for my last few trips with my wife. I have the evernew pot and Soto OD1R. I haven't needed a hot water container. Also, the stove and a small fuel canister (upside down) stow nicely inside the pot and last 5+ days for us. It's compact, fast to boil, flexible – individually swapable components , and much lighter than the jetboil and msr options.
On my last two shoulder season trips (Beartooths with lows of 25F, Banff with lows of 15F), I brought both the "Cadillac" and a system similar to the one you describe here to compare performance. The only significant difference is that I used a remote canister stove weighing .75 oz more than the Supalite.
In the Beartooths we had wind gusts up to 100mph and despite being in a sheltered campsite and using my pack and rocks, borrowing the windscreen from the Cadillac made a big difference. I felt that the extra 1.4 oz was worth it, even had I not brought the alcohol stove. I felt it was a tossup between the two systems otherwise.
In Banff, the alcohol stove was frustratingly slow. Somewhere between 25F and 15F, the canister solution won out.
Hi Andrew. Do you ever notice gas leaking out of the canister when attaching your stove? I've had this issue with my SnowPeak Litemax stove recently. Any help and advice is appreciated. Happy Halloween! Thanks.
That is normal. The male piece on the stove penetrates the canister before the threads are air-tight. It's like filling up a bicycle tire with Schrader valves.
At less than an ounce and only about $14, the BRS 3000t has caused me to give up on alcohol stoves completely. It's a game changer for me on solo trips. I still marvel at how effective and light the tiny BRS is when cooking for one person. Pot support isn't great for larger pots, but I've had no problem with small pots.
For larger pots or on Boy Scout outings, I am very impressed with the DPower remote canister. In my opinion, it is perfect for scouts cooking in patrols. It weighs about the same as a Gigapower but is much more stable. The price is very cheap and it has held up extremely well given the abuse that scouts can put on gear. It has excellent simmer control which allows for more elaborate meals than just "boiling water". Bang for the buck, its hard to beat.
After switching from a Snow Peak Gigapower to a Caldera Cone in 2008, I have never been able to figure out a situation where an integrated stove (like a jetboil) made sense even on an 11 day trip in 2015, the Caldera Cone was still lighter. My dad is going with me back to Alaska for 11 or 12 days next summer and if we boil water for oatmeal in the morning and dinner at night, one of the lightest jetboils does come out lighter, but not by a ton. It doesn't work out with a heavier jetboil or MSR Reactor/Windboiler (which seam like better stoves otherwise).
For trips a week or less, I never could make the numbers work, unless you boil tons of water, which I don't.
You are not looking at it from the right perspective. It's not about weight-savings. It's about convenience. Canister stoves are generally very user-friendly, and integrate stoves take it to the next level with an even easier assembly (screw two pieces together, that's it) and with extremely fast boil times.
To nest all my solo cook kit together with the 900 mL Evernew pot, I purchased a Pioneer Woman 13 fl. oz. round container as a cup. It weighs 1.5 oz. without the lid. Approx. $3 from W.Mart. It comes in green and blue colors. Small Snow peak Giga power 110g canister, turning upside down, will drop into this cup nicely. To offset the small canister capacity, I built a homemade cozy to cover the pot's exterior. Reflectix cozy weights 0.8 oz. I sewed my cozy, rather using sticky tape to save a few tenth of an ounce. I found using sticky tape has a tendency to peel in the field.
Pioneer Woman cup with no lid, Snow Peak Giga power 110g canister, Supalite stove, BIC lighter and shorten spoon can all fit into the 900 mL Evernew pot to minimize volume. Then, I enclose my pot with a homemade cozy.
I just want to share this tip with the forum.
I'd love to use the Supalite or even a Gigapower. However, wind is almost always a problem for me in the Sierras. Since I usually backpackin groups of 2-3, need wind protection, and need stability, a remote canister (MSR Windpro II) works best for me.
What is your opinion of the heat-echanger equiped pots (http://www.campsaver.com/olicamp-xts-pot-cookware-pots)? Fot a bit of extra weight, you can extend your fuel and shorten your heat times considerably. I think break-even for pot weight to fuel weight savings is four man-days during summer temps. Probably shorter with colder air temps.
I know of such pots but I have not used one. As you said, it's a tradeoff between base weight and fuel efficiency. Not sure where the break-even point is. But sometimes that does not matter — if the stove becomes more usable in, say, windy conditions, you might overlook easily the difference of an ounce.
I am a big fan of your Cadillac set up! My current UL stove set up is just a Snowpeak 700ml cup/pot with the Snowpeak litemax canister stove and a piece of foil as a windscreen. This set up is basically only good for heating water for freeze-dried meals, not so much for actual cooking. I have been inspired by your food and stove posts and I am seriously considering the Cadillac as my next stove system.
My question – The cost of the Cadillac is cost prohibitive to me. As much as I would like the Caldera Ti-Tri, the aluminum Caldera Cone seems more financially viable. Can you speak to the durability of the Caldera Cone? Will it last a couple years? Is there a chance it could collapse under the weight of the pot? I am worried that it will be flimsy or dent very easily. I typically go on 2 or 3 weekend type backpacks a year, with a longer 1 to 3 week trip every other year. Is this a situation where the extra $45 is really really worth it?
Buying an $80 metal cone is a hard sell to my (pregnant) wife….
I think you'd be okay with the aluminum version. It is not as durable, and it is not as packable as the Ti version. But if you take care of it, it will take care of you. For the ultimate answer, I would simply call Trail Designs — one of the owners will probably answer the phone. Please tell them I sent you along.
I have had the same Aluminum Caldera Cone since 2008 and it has been used extensively. It looks pretty rough but is still functional. My 12-10 stove is the original too and it looks worse and the epoxy between the inner and outer can has come loose (so it rattles a bit) but I have noticed no loss in efficiency or functionality. The newer cones have a titanium re-inforcement on the dove-tail but I have had no problems with mine without.
Unless you really want to burn wood – buy the aluminum one – for most users the Ti version is a waste.
Andrew, have you considered using the HDPE 16oz Nalgene? Pros seem to be that it's slightly lighter, has better impact resistance, but seems to hold smells more than the regular plastic, which isn't an issue if it's a dedicated coffee mug/hot water bottle.
I have some of those bottles. You could definitely swap one in this case, and save a little bit of weight and a few dollars.
Putting them in the dishwasher solves the smell issue. Several times a year I put my peanut sauce recipe in these bottles, and they're as good as new after one cycle in the dishwasher.
I also noticed what appears to be an reusable coffee filter in the picture up top. Can you speak to how this has worked for you, and how it works in conjunction with the 16oz Nalgene?
I believe that a wide-mouth is just wide enough for that coffee filter, and if you pour slowly you'll be okay.
But the filter is better used with a wide mug, or a second pot. That photo was taken a few years ago, but if I recall correctly I think I would heat up the water and grounds in my pot, then filter out the grounds over my buddy's pot. We'd heat up the coffee again if necessary, then we'd decant the coffee into our respective mugs/bottles.


Marshall, the family-owned dealer group, has announced today the completion of its acquisition of the Lincoln Jaguar business from the Cooperative Society.
This acquisition brings to four the total number of Jaguar dealerships in the Marshall Group and means that Marshall has now doubled its representation with Jaguar in the last 3 years. The Group's other Jaguar dealerships are in Peterborough, Cambridge and Ipswich.
Speaking about the acquisition, Daksh Gupta, Chief Executive Marshall Motor Holdings, said: "This is a great acquisition for Marshall as it now gives us a larger contiguous territory, which serves the East of England from the Humber down to East Anglia".
"Since 2008 we have been reshaping our portfolio and focusing on key and core brand partner relationships. This acquisition is consistent with this strategy to increase the depth of our representation".
"It is also consistent with our strategy to de-risk our previous over exposure to Cambridge and Peterborough. We have represented the Jaguar brand for nearly 40 years now and are delighted to be growing with Jaguar, especially at a time when their investment plans for the growth of their own business are so exciting".
colleagues to the Group and we look forward to meeting them in the next few days as we introduce them to their new colleagues across the rest of the Marshall Group".


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HomeEncyclopedia of Communist BiographiesGGuest David
Guest David
September 19, 2008 admin G 0
David Guest
Guest was a noted Communist intellectual, first class scholar at Cambridge and International Brigadier who was killed during the battle of the River Ebro in July 1938.
He was born in 1911, his father being Dr Hayden Guest, Labour MP for Southwark (1923-27) and Islington North (1937-50), for whom a hereditary peerage – a Baronetcy – was created on his retirement from the Commons.
His mother was Muriel Carmel Goldsmid,daughter of Colonel Albert Edward Williamson Goldsmid, a career army officer from a historic family of financiers. An ardent Zionist, in 1895 he founded the Jewish Lads and Girls Brigade.
David became a student at Cambridge University in 1929, securing a first honour's degree in Mathematics. He went on to study Mathematics & Philosophy at Göttingen, in Germany, from between 1930-1931. Seeing the growing threat of fascism first hand, he first became involved in anti-fascist activity while in Germany, for which he received two weeks jail. On his return to Cambridge, it was therefore not surprising that he joined the Communist Party in 1931.
Guest, along with Maurice Cornforth, James Klugmann, John Cornford (see alphabetical entries on the site for each of these), John Lehmann (the poet and associate of Isherwood and Auden) and four or five others established a Communist cell at CambridgeUniversity. By 1935, it had risen to 25 members and then jumped to about 150 across the whole university soon after. TrinityCollege alone had 12 members and weekly meetings in the students' rooms.
This reflected a conscious drive by the Communist Party to orientate some of its work towards students. In 1932, the Communist Party Federation of Student Societies (FSS) was established, under the watchful eye of Dave Springhall, YCL national organiser.
Initially the FSS had about twenty organizations affiliated, including at the LSE (a Marxist Society was established in 1931), Oxford (the October Club, established 1932) and the universities of London, Reading, Durham, Leeds, Manchester and Cambridge (where there was a long-established student Socialist Society). The Federation of Student Societies journal was the "The Student Vanguard". It was during this period of the early 1930s, that enthusiasm for the party secured the election of Philip Toynbee as the Communist Party's first Oxford Union President (OxfordUniversity) and a Communist MP for the CardiffUniversity constituency.
Willie Gallagher visiting CambridgeUniversity in 1934 set the tone in stating: "We want people who are capable who are good scientists, historians and teachers … we need you as you are; if you have a vocation, it's pointless to run away to factories. We want you to study and become good students." Out of this meeting came the slogan, "Every Communist student a good student". Dennis Healy, a Communist student at Oxford University in 1937, has recalled that "Communists started shaving, tried to avoid being drunk in public, worked for first-class degrees and played down Marxism-Leninism".
The students themselves wrote the following ironic ditty:
Dan, Dan, Dan
The Communist Party man
Working underground all day
In and out of meetings
Bringing fraternal greetings
Never seeing the light of day.
In 1933 Guest moved to Battersea, South London, lodging with the Simes family in Bolingbroke Grove, to work in the Party's "Peoples' Bookshop" at 115 Lavender Hill. He soon became active in Battersea Young Communist League. Bob Gorham, Battersea YCL's Secretary, said of Guest that: "David would go out whitewashing until 2 or 3 in the morning". While working at the bookshop he joined the shop workers union. In May 1935, he organised a Youth Peace Parade of fifty young people, some dressed as nurses, others with gas masks and with stretchers, to warn of war.
Guest also lectured to Communist Party classes on Mathematics and Angela Guest, his sister, commented on his work in Battersea that: "Here David learned things about the working class life that few who are not workers can appreciate in full. He saw families sell their furniture stick by stick so they could buy food. He saw families thrown into the street for the heinous crime of spending their rent money on food. He saw families refused relief without cause."
For a period of time he taught in Moscow but returned to England to lecture at UniversityCollege in Southampton. In 1938 he declared his joining of the International Brigade: "Today we have certainly entered a period of crisis, when the arguments of 'normal times' no longer apply, when considerations of most immediate usefulness come in. That is why I have decided to take the opportunity of going to Spain…There is … the need to show that there is no division between party workers and intellectuals over this matter, particularly in view of the large numbers of young workers who have gone from Battersea."
As well as David Guest, Battersea activists included: Ralph Fox (killed Cordoba, December 1936), Tom Oldershaw (killed Aragon, March 1938), Martin Messer (killed Boadilla, December 1936), David Halloran (killed Jarama Feb 1937), Michael Kelly (killed Brunete, July 1937), Bert Simes, George Leeson, Joe Ilean, Percy Cohen, Eddy Bee, Clive Branson, G W Baker, Bill Davison, Angela Guest and the (unnamed) future medical director of Battersea's Public Health Department.
Guest threw himself into the Republican struggle. In a letter home from Spain, Guest wrote: "I have…a lively desire to explore whole fields of theoretical work, mathematical, physical, logical … but of course, this is not possible now – today the struggle". Despite Guest's "thin and emancipated" body, his friend, Bill Davison of Battersea, reported that "he had some guts, did Dave". Rhonnda miner, Billy Griffiths, stated that he performed "Herculean tasks" in the fighting.
In July 1938, at the battle of Ebro, the British Battalion was ordered to take Hill 481, known to the men as `The Pimple'; they got within a few metres of well-fortified positions on the summit before, over the next six days, these brave attempts by the Battalion to take the Hill were repulsed. It was during this battle that Guest was killed.
After his death, notes he had made while lecturing at the Marx Memorial Workers' School were published as `A Text Book of Dialectical Materialism in 1939. His sister, Angela, who had also served in the International Brigade in Spain, became a doctor in 1945 and worked for the World Health Organisation, but was tragically killed in a car crash in Africa in 1965.
Sources: Jim Fryth `The signal was Spain'; N Branson `History of CPGB (1927-1941); Francis Beckett `Enemy Within'; J Hopkins `Into the Heart of the fire'; M Squires `Aid to Spain in Battersea'; David Guest "Reasons for my decision"; Carmel Haden Guest (ed) `A scientist fights for freedom – a memorial'.
Conway Jim
Mullins Jack
Nicholson David
July 20, 2013 admin N 0
David Nicholson Nicholson was born in Nottingham in 1956 and educated at Forest Fields Grammar School. He graduated from Bristol Polytechnic with a history and politics degree and began work in the health sphere. At […]
Ramsay David
June 24, 2012 admin R 0
Dave Ramsay Dave Ramsay was a pattern maker by trade and a member of the Amalgamated Society of Engineers, then of the AEU. He was a member of the Socialist Labour Party in Leicester. An anti-war […]
Jones David Ivon
October 11, 2011 admin J 0
David Ivon Jones D I Jones was born in 1883 in Aberystwyth, Wales. Jones was orphaned as a young child and brought up by his grandparents, but his grandmother also died when he was […]


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December 22, 2022 18.xii.22 Advent IV / America / Culture War / Features / Lifestyle / Politics / The Daily Telegraph / The Telegraph / War
Zelensky's speech to Congress in full: 'We defeated Russia in the battle for minds of the world'
Ukrainian president delivered an historic address to the US Congress, declaring that his nation is 'alive and kicking'…
President Volodymyr Zelensky delivered an historic speech to the US Congress on Wednesday, declaring that Ukraine is "alive and kicking" and would "never surrender".
In a 20-minute speech, repeatedly interrupted by standing ovations, the Ukrainian president invoked the spirit of the Second World War and the American War of Independence.
He told senators and members of Congress his soldiers needed more weapons, including planes, and that US spending on Ukraine was not "charity" but an "investment in global security and democracy".
Read his speech in full below…
Evening Meditations for the Fourth Thursday in Advent ~ St Alphonsus Liguori
A Road Map for Catholic Families — Integrated Catholic Life™


Philippe Coutinho squad number: Barcelona star leaves No.7 free for new signing – but who?
BARCELONA still have the No.7 shirt available – but who could take it?
Barcelona have handed Philippe Coutinho the No 14 shirt following the departure of Javier Mascherano – but that leaves one major number free for a potential new transfer.
The No 7 shirt remains open for a world class signing, with many suggesting Antoine Griezmann – Atletico Madrid's current No 7 – could be that man.
Barca have been linked with plenty of attacking options during the January transfer window, including several Premier League stars.
The £142million deal for Coutinho wasn't enough to gift him the iconic number, leading to big questions over who is worthy of taking the shirt.
Take a look through the gallery to reveal seven players linked to Barcelona who could take the No 7 kit.


On November 2, Vladimir Putin will address the fourth Soobshchestvo active citizens' forum, which will be held in Gostiny Dvor.
The discussion will focus on the development strategy of the country and civil society. The participants will take part in a number of panel discussions on the strategic areas of development mapped out in the Presidential May Executive Order.
The President will also meet with the winners of the contest for socially meaningful projects My Project For My Country, which include leaders of non-profit organisations, heads of social projects and socially proactive individuals.
The Civic Chamber has held the Soobshchestvo forum since 2015. It is aimed at creating a venue for the exchange of opinions between civil society, business and the authorities.


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John F. Gorman  (1859–1889), nicknamed "Stooping Jack", was a 19th-century professional baseball outfielder and third baseman.  He continued to play in the minor leagues through 1888.

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Wells Fargo Mortgage – How to Apply?
Today, more and more individuals are looking to buy their own homes. Even millennials are starting to see the importance of investing in a place they can call their own. Whether it's saving for the future and maximizing their profits or simply desiring to settle down, buying a home is now more important than ever.
If you have been thinking about purchasing your own parcel of land or buying a house on the market, the Wells Fargo Mortgage might be the best thing you can get your hands on. Apart from helping you finance your dream home, this mortgage program can also help you get affordable interest rates and closing cost credit. To know more about this type of mortgage, read on.
Whether you are thinking of buying a house, actively shopping, or you already found your dream place, a Wells Fargo Mortgage can give you the help you need. Aside from helping you choose from fixed-rate mortgages or adjustable-rate mortgages, you can also avail of loan term options that have a longer period of time. Through these features, you can better budget your monthly payments.
Even better, depending on the type of mortgage you choose, you can protect yourself from being affected by rising interest rates, helping you get the most of your investments.
The best of all, you can find rates that are suited for your lifestyle and your personal journey. Using the Wells Fargo online calculator, you can already explore how much you may be able to borrow and how much you can afford. If you are ready to purchase, you can get pre-approved and have the chance to gain access to enviable deals and discounts.
Getting your own Wells Fargo Mortgage is easy. All you need to do is head on to their website and fill out an online application. You can also apply over the phone or find a local consultant near you.
To proceed with your application, you will need to provide details of your financial information. Other important details you need to provide include proof of billing address, contact number, personal information, and income details. You will also need to declare your assets and liabilities, real estate properties, and demographic information.
If your Wells Fargo Mortgage application is approved, you can get financing ranging from $20,000 to $300,000 depending on your creditworthiness.
Purchasing rates for the Wells Fargo Mortgage program range from 3.625% to 4.512% depending on the agreed term period. Individuals can pay their loans on a fixed rate from 15 to 30 years. Meanwhile, ARM loans are also available for 5/1 and 7/1 terms.
For example, those who are borrowing a $243,000 loan when purchasing a house in Camden County, New Jersey will need to shell out $1,180 per month. This has a given interest rate of 3.875% and an APR of 4.217% with a credit score of 759.
If you need help purchasing your first home, the Well Fargo Mortgage program is one you shouldn't miss. Apply now and you might just get preferential rates today.
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