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Panorama™
Noninvasive prenatal testing (NIPT)
Panorama is a blood-based genetic, prenatal screening test of the pregnant person that screens for common chromosomal conditions that affect a baby's health. Panorama uses SNP*-based technology to deliver highly accurate results and unique insights for both singleton and twin pregnancies.
Panorama can be performed as early as nine weeks gestation. Most results will be returned to your doctor within 5-7 calendar days.
Panorama is a screening test, which means that this test does not make a final diagnosis. A high risk result means that your pregnancy has a higher chance of having a specific genetic condition. However, you cannot know for sure if your baby has that condition based upon the screening result alone. All medical decisions should be made after discussion with your healthcare provider regarding diagnostic testing during the pregnancy, like chorionic villus sampling (CVS) or amniocentesis, or testing the baby after birth.
*SNP, single nucleotide polymorphism
Panorama, the most ordered NIPT, trusted in more than 3 million pregnancies, can assess conditions that can affect your baby's health by doing a simple blood draw on you.1,2
CA residents: Find out more about how NIPT is offered under the California Prenatal Screening program and how Panorama can supplement it by clicking here.*
Personalized results
Panorama offers a personalized report, which indicates whether your baby has a high or low chance for certain genetic conditions. Your report could state the following:
A low risk result means that the chance that your baby has one of the conditions tested by Panorama is very unlikely but not zero — less than 1 in 10,000 for most conditions.1,3
Panorama is a screening test, which means that this test does not make a final diagnosis. A high risk result means that your pregnancy has a higher chance of having a specific genetic condition. However, you cannot know for sure if your baby has that condition based on screening results alone.
If you receive a high risk Panorama result, speak with your healthcare provider (HCP) to discuss which next steps you could decide to do, such as genetic counseling, detailed ultrasound, and the option of diagnostic testing.
All medical decisions should be made after discussion with your HCP regarding diagnostic testing during the pregnancy, like chorionic villus sampling (CVS) or amniocentesis, or testing the baby after birth.
About 1 in 65 tests could receive a no result or other type of result.3 You should speak with your HCP about these result types and whether you should consider having a second blood draw to do the test again. There is also a small chance that Panorama will have a result relating to your genetics or your physical health.1
Conditions Screened For
Panorama screens for common genetic conditions that are caused by extra or missing chromosomes in the baby's DNA. Because Panorama uses a unique technology to distinguish between the pregnant person's and the baby's DNA, it is the only NIPT that tests for triploidy, and it can avoid known sources of error that affect other NIPTs.4 Some conditions, such as Down syndrome, are caused by extra copies of a specific chromosome. Others, such as microdeletions, occur when a chromosome is missing a small piece of genetic information.4
TRISOMIES*
Babies with Down syndrome have three copies of chromosome 21 and have intellectual disabilities that range from mild to severe. Children with Down syndrome will need extra medical care depending on the child's specific health problems. Early intervention has allowed many individuals with Down syndrome to lead healthy and productive lives. The presence of medical conditions, like heart defects, can affect the lifespan in these children and adults; however, most individuals with Down syndrome will live into their 60s. Miscarriage occurs in about 30% of pregnancies with Down syndrome while overall about 1 in 700 babies are born with Down syndrome.
Trisomy 18 (Edwards syndrome)
Babies with trisomy 18 have three copies of chromosome 18 and have severe intellectual disabilities and birth defects typically involving the heart, brain, and kidneys. Babies with trisomy 18 can also have visible birth defects such as an opening in the lip (cleft lip) with or without an opening in the roof of the mouth (cleft palate), a small head, clubbed feet, underdeveloped fingers, and toes, and a small jaw. Unfortunately, most pregnancies with trisomy 18 will miscarry. If born alive, most affected babies with trisomy 18 will pass away within the first few weeks of life. About 10 percent survive to their first birthday. Trisomy 18 occurs in approximately 1 in 3,000 live births.
Trisomy 13 (Patau syndrome)
Babies with trisomy 13 have three copies of chromosome 13 and have severe intellectual disabilities. They often have birth defects involving the heart, brain, and kidneys. Visible abnormalities include extra fingers and/or toes or an opening in the lip, with or without an opening in the palate. Given the severe disabilities, most pregnancies affected by trisomy 13 will miscarry. If born alive, most affected babies with trisomy 13 will pass away within the first few weeks of life. About 10 percent survive to their first birthday. Trisomy 13 occurs in approximately 1 in 5,000 live births.
SEX CHROMOSOME ANEUPLOIDIES**
Monosomy X (Turner syndrome)
Babies with monosomy X are biological females who have one X chromosome instead of two. Unfortunately, a high proportion of pregnancies with monosomy X will result in a miscarriage in the first or second trimester of pregnancy. Babies with monosomy X that make it to term may have heart defects, learning difficulties, and infertility. In most cases, babies with monosomy X will need extra medical care including hormone therapy at various stages of life.
XXY Syndrome (Klinefelter Syndrome)
Babies with XXY syndrome have two X chromosomes and one Y chromosome (XXY). This condition can be associated with learning difficulties and behavioral problems. People with Klinefelter syndrome might be infertile. About 1 in 500 biological males will be born with Klinefelter syndrome.
Triple X syndrome
Babies with Triple X syndrome have three X chromosomes (XXX). Children with this condition could be taller than average and might experience learning difficulties or behavioral problems. Approximately 1 in 800 biological females will be born with three X chromosomes.
XYY Syndrome (Jacob's Syndrome)
Babies with XYY syndrome have one X chromosome and two Y chromosomes (XYY). Most babies with XYY syndrome do not have any birth defects. Children with XYY could be taller than average and have an increased chance for learning, speech, and behavioral problems. Approximately 1 in 1,000 biological males will be born with one X chromosome and two Y chromosomes.
MICRODELETIONS**
*Not available for egg donor or surrogate pregnancies or in cases of dizygotic (non-identical twins)
22q11.2 deletion syndrome
22q11.2 deletion syndrome, also called DiGeorge syndrome or Velo-Cardio-Facial syndrome (VCFS), is caused by a missing piece of chromosome number 22. About one in every 2,000 babies is born with 22q11.2 deletion syndrome. The majority of children with this disorder have heart defects, immune system problems, and specific facial features. Most children with 22q.11.2 deletion syndrome have mild-to-moderate intellectual disability and speech delays; some will also have low calcium levels, kidney problems, feeding problems, and/or seizures. About one in five children with 22q11.2 deletion syndrome have autism spectrum disorder; 1 in 4 adults with 22q11.2 deletion syndrome have a psychiatric illness, like schizophrenia.
Prader-Willi syndrome†
Prader-Willi syndrome occurs when either a small piece of chromosome 15 is missing or when both copies of chromosome 15 come from the same parent (called uniparental disomy, or UPD). Babies with Prader-Willi syndrome have low muscle tone and problems with growth and feeding. Children with Prader-Willi syndrome have delayed milestones, short stature, rapid weight gain leading to obesity, and intellectual disability. About 1 in 10,000 babies are born with Prader-Willi syndrome.
Angelman syndrome†
Angelman syndrome happens when either a small piece of chromosome 15 is missing, or when both copies of chromosome 15 come from the same parent (called uniparental disomy, or UPD). About 1 in 12,000 babies are born with Angelman syndrome. Babies and children with Angelman syndrome have severe intellectual disability, delayed milestones, seizures, and problems with balance and walking.
1p36 deletion syndrome
1p36 deletion syndrome, also referred to as Monosomy 1p36 syndrome is caused by a missing piece of chromosome 1. Children with 1p36 deletion syndrome have intellectual disabilities. Most have heart defects and weak muscle tone. About half of affected individuals have seizures (epilepsy), behavioral problems, and hearing loss. Some children with 1p36 deletion syndrome also have vision problems or additional birth defects of other organs. About 1 in 5,000 newborn babies has 1p36 deletion syndrome.
Cri-du-chat syndrome
A missing piece of chromosome 5 causes Cri-du-chat syndrome, also called 5p- (5p minus) syndrome. The name "Cri-du-chat" was given to this syndrome due to the high-pitched, cat-like cry that babies with this syndrome often make. Babies with Cri-du-chat syndrome typically have low birth weight, a small head size, and weak muscle tone. Feeding and breathing problems are common in infancy. Children with this disorder have moderate-to-severe intellectual disability, including speech and language delays. They may also have growth delays, behavior problems, and some have curvature of the spine (scoliosis). About one in every 20,000 babies is born with Cri-du-chat syndrome. They may also have heart defects, growth delay, behavior problems and some have curvature of the spine.
TRIPLOIDY*
Only NIPT that tests for triploidy
Babies with triploidy have a complete extra set of chromosomes for a total of 69 chromosomes instead of the usual 46. At 10 weeks gestation, one in 1,000 pregnancies is affected by triploidy. It is extremely rare for these pregnancies to reach term as they typically spontaneously miscarry early in pregnancy. Those few liveborns usually pass away within days of delivery due to heart, brain, and kidney problems. Babies with triploidy also often have birth defects affecting the extremities and face.
Carrying a baby with triploidy can increase a mother's risk for a variety of conditions: pre-eclampsia (which can lead to seizures) and excessive bleeding after delivery. In rare instances, triploid pregnancies can persist and progress to a type of cancer called choriocarcinoma. Knowing about triploidy allows the physician to monitor the health of the mother appropriately.
Complete Test Specifications for Singleton, Egg Donor, Gestational Carrier, and Monozygotic (Identical) Twins
Definition of performance terms
Sensitivity is the ability to correctly identify a truly high risk case as high risk. For example, in a group of Trisomy 21 cases, Panorama will correctly identify more than 99% of those cases.
Specificity is the ability to correctly identify an unaffected case as low risk.
Positive Predictive Value (PPV) is the likelihood the result says high risk and the fetus is actually affected. For example, when Panorama shows a high risk result for Trisomy 21, there is a 95% chance that the fetus is affected by Trisomy 21. In other words, 5% of the time, you could get a high risk result when the fetus is not affected by Trisomy 21.
Negative Predictive Value (NPV) is the likelihood the result says low risk and the fetus is truly not affected.
Sensitivity (95% CI)
Specificity (95% CI)
Trisomy 21*3,5
99.0% (CI 97.1-100) >99% (CI 99.93-99.99) 95% >99.99%‡
94.1% (CI 82.9-100) >99% (CI 99.96-100) 91% >99.99%‡
>99% (CI 73.5-100) >99% (CI 99.96-100) 68% >99.99%‡
Monosomy X**5-8
94.7% (CI 74.0-99.9) >99% (CI 99.7-100) 78% >99.99%‡
Triploidy**9,10
>99% (CI 66.4-100) >99% (CI 99.5-100) 11% >99.99%‡
XXX, XXY, XYY**11
73.1% (CI 61.0-85.1) 99.9% (CI 99.90-99.99) 86.4% 99.87%‡
22q11.2 deletion syndrome**12
83.3% (CI 51.6-97.9) >99% (CI 99.91-99.98) 53% 99.9%||(CI 99.9-100)
1p36 deletion syndrome**13,14
>99% (CI 2.5-100) >99% (CI 99.1-100) 7-17%|| 99.98-99.99%||
Angelman syndrome**†13,14
95.5% (CI 77.2-99.9) >99% (CI 99.1-100) 10%§ >99.99%
Cri-du-chat syndrome**13,14
>99% (CI 85.8-100) >99% (CI 99.1-100) 2-5%|| >99.99%
Prader-Willi syndrome**†13,14
93.8% (CI 69.8-99.8) >99% (CI 99.1-100) 5% >99.99%
Female6,7,8
>99.9% (CI 99.4-100) >99.9% (CI 99.5-100)
Male6,7,8
Test Specifications for Dizygotic (Nonidentical) Twins1
70% >99.975%
Find out more about the Panorama test
1Natera internal data on file
2Definitive Healthcare report to identify billing for NIPT based on US Clearinghouse for Medical Claims using CPT codes 81420, 81507, 81422.
3Dar et al. Am J Obstet Gynecol. 2022 Aug;227(2):259.e1-259.e14.
4ACOG Practice Bulletin 226. Obstet Gynecol. 2020 Oct;136(4):859-867.
5DiNonno et al. J Clin Med. 2019 Aug 26;8(9):1311.
6Nicolaides et al. Prenat Diagn. 2013 June;33(6):575-9.
7Pergament et al. Obstet Gynecol. 2014 Aug;124(2 Pt 1):210-8.
8Ryan et al. Fetal Diagn Ther. 2016;40(3):219-223.
9Nicolaides et al. Fetal Diagn Ther. 2014. 35;(3):212-7.
10Kantor et al. Prenat Diagn. 2022;42:994–999.
11Martin et al. 25th International Conference on Prenatal Diagnosis and Therapy Meeting; June 6-8, 2021.
12Dar et al. Am J Obstet Gynecol. 2022 Jul;227(1):79.e1-79.e11.
13Martin et al. Clin Genet. 2018 Feb;93(2):293-300.
14Wapner et al. Am J Obstet Gynecol. 2015 Mar;212(3):332.e1-9.
* CA residents: If your clinician ordered screening through the California Prenatal Screening program using Natera's Vasistera™ NIPT, Panorama™ will only screen for supplemental conditions. If this is the case, trisomies 21, 18 and 13, and fetal sex (optional) will be screened using Vasistera™ NIPT and will be reported separately.
** Not available for egg-donor or gestational carrier pregnancies or in cases of dizygotic (nonidentical) twins. Triploidy and microdeletions except for 22q11.2 deletions are not available for monozygotic (identical) twins.
† This test has been validated on full region deletions of Prader-Willi syndrome/Angelman syndrome (PWS/AS) only and might be unable to detect smaller deletions. It has not been validated for other molecular mechanisms which could cause PWS/AS such as uniparental disomy (UPD) or methylation.
‡ Ongoing clinical follow-up is performed to ensure the NPV does not fall below the quoted value but follow up is not obtained for all low risk calls.
§ PPV for 22q11.2 deletion syndrome and Angelman syndrome in published studies was 53% and 10% respectively when no ultrasound anomalies were seen and was up to 100% when ultrasound anomalies were seen prior to testing.
|| Dependent upon fetal fraction (FF). For 22q11.2 deletion syndrome, only the paternal allele is evaluated at FF ≤ 6.5%. For 1p36 deletion syndrome and Cri-du-chat syndrome, only the paternal allele is evaluated at FF < 7%. For Angelman syndrome, no risk assessment is reported at FF < 7%. For Prader-Willi syndrome, no risk assessment is reported at FF ≤ 2.8%.

redpajama_set_name: RedPajamaCommonCrawl


If you need credit repair, debt settlement could be one of the reasons. A debt settlement can really damage your credit, and it will take some time to rebuild it successfully. Here are a few steps that you could take to repair your credit score after debt settlement.
The first thing that you have to do is start using credit again. After you have just settled a large amount of debt, your instinct may be to avoid using credit all together. You do not want to have to worry about the possibility of accumulating more debt than you can handle. However, you need to start using credit on a smaller scale again in order to build it back. If you do not use credit, it dries up and your score will suffer from it even more.
Open up some type of credit account if you can and make a few purchases with it. If you can open a credit card, this might be the easiest route to take. If your credit was too severely damaged by the debt settlement to open a traditional credit card account, you may have to look at other options. For example, you may have to open a secured credit card or a prepaid one. A secured credit card is actually tied to some asset instead of just giving you an unsecured line of credit to use. This makes it safer for the lender and will still allow you to use credit. Once you get this credit account, you should make only a few small purchases periodically. This is not an invitation to max out your credit card. Use it within reason.
Once you have charged something on your credit account, you need to make sure that you pay the bill before the due date. Completely pay off the balance each month: do not allow the balances to accumulate interest. You should get in the habit of paying your credit account bills every single month.
In addition to that, you need to make sure to pay all of your other bills on time as well. Your utilities, your car payment, mortgage, and everything else needs to be on time every single month. This can have a huge impact on your credit score overall. When credit bureaus calculate your credit score, as much as 35 percent of the equation is made up of how you pay your bills. Therefore, it is the single largest factor in determining your credit score.
As you start to rebuild your credit, you need to try to get a nice mix of credit accounts. Lenders like to see that you can handle different types of credit before they give you a large loan. For example, if you have a credit card, a store account, a student loan, car loan, and mortgage, you have a nice mix of different types of credit. If you utilize them properly, this can have a nice effect on your credit score.


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University of Iowa, police investigate reported racist attack
(Reuters) – The University of Iowa and police said on Wednesday they are investigating as a hate crime a report that a black student was beaten by a group of white men in a racially motivated attack.
Marcus Owens, a 19-year-old freshman from Naperville, Illinois, was beaten after he left a bar on Saturday night by three white men who yelled racial abuse at him, according to an ABC television affiliate in Chicago.
The attack left Owens with a damaged eye socket. He also had his front teeth knocked out and needed about a dozen stitches to close a cut on his lip, ABC-7 in Chicago said.
An individual came to the Iowa City police department late Monday to report that he had been assaulted, police said in a statement. Police declined to identify the victim and suspects, saying they do not release the identities of victims and citing pending charges against the suspects.
The victim told the police that on late Saturday, an individual struck him multiple times in an alleyway and then he was struck several more times by other people while being called racial slurs, the statement said.
The victim later was treated for non-life threatening injuries at a university hospital, the statement said. Owens was released from the hospital on Monday, the station reported.
The suspects were described as three white males, about 19 to 22 years old, and of average height, the statement said.
The university was "deeply disturbed" and was seeking more details of the attack, officials said in Twitter posts after being contacted by the broadcaster.
Owens had just left an off-campus bar when three men approached and began punching him, his uncle Darrell Owens told the news station.
"This is 2016. You shouldn't expect this to happen," he said.
(Reporting by Brendan O'Brien in Milwaukee and Suzannah Gonzales in Chicago; editing by John Stonestreet, Bernard Orr)
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The Consortium Welcomes 20 New Corporate Partners Seeking Diverse MBA Talent
Under the direction of the Development Department, The Consortium welcomed 20 new corporate partners in less than a year. The companies span all industries and partnership levels, but the one thing they have in common is their commitment to advancing The Consortium's mission to enhance diversity and inclusion in global business education and leadership — as well as a desire to hire top diverse MBA talent.
We offer a warm welcome to the following companies:
Premiere Plus Level
Align Technology
As a premiere plus corporate partner, Align Technology intends to leverage the Consortium's diverse talent pool and increase the number of MBAs in its workforce to help drive continued innovation and adoption of the Align digital platform. "Align's leadership in digital orthodontics reflects the passion and purpose of our employees who represent many different backgrounds, beliefs and perspectives," says Edward Turner, senior marketing program leader. "We are excited to be working with The Consortium to further strengthen and expand our diverse talent."
Promoter Level
FTI Consulting
With the goal of achieving gender parity in hiring and increasing its presence at diversity events, FTI Consulting has set specific targets with regard to campus and graduate recruiting. As such, the business advisory firm made the decision to partner with The Consortium this year. "The Consortium mission is in alignment with FTI Consulting's Diversity, Inclusion, and Belonging Strategy as we are committed to attracting diverse professionals to ensure we are building an inclusive firm and culture," a company representative said.
Committed to the values of diversity and inclusion, H&M focuses its efforts on providing opportunities for everyone within its communities to succeed. "The Consortium's mission of connecting high-caliber underrepresented students with top-tier MBA programs is about creating opportunities for greater success," says Donna Dozier Gordon, head of inclusion and diversity, H&M USA. "This work is closely aligned with H&M's commitment to I&D, particularly our focus on empowering members of the communities in which we live and work to be more and do more through our support. We are thrilled to find and partner with those who are similarly motivated like The Consortium."
With diversity, equity and inclusion an integral part of its mission for more than 60 years, medical technology company Medtronic joined The Consortium to have even greater impact. "Naturally, supporting the advancement of The Consortium's mission supports our own mission to alleviate pain, restore health, and extend life around the world," a company representative said. "We understand that we are better positioned for resilience and business performance when our teams are diverse."
One way Vertex Pharmaceuticals demonstrates its commitment to inclusion, diversity and equity is by developing a diverse pipeline of talent. "We know that when we embrace our unique perspectives and strengths, we are positioned to innovate at our best and solve some of the most difficult challenges in science and medicine," says Diana Cruz Solash, vice president, talent and inclusion, diversity and equity, Vertex Pharmaceuticals. "We are proud to partner with The Consortium as its mission — to enhance diversity and inclusion in global business leadership by reducing the underrepresentation of African Americans, Hispanic Americans and Native Americans — aligns with our ambition to realize the full potential of our rich diversity to deliver on our mission for patients."
Advocate Level
The Consortium's mission aligns with American Airlines' ongoing effort to create an open, inclusive culture and workplace where people from all backgrounds feel welcome and valued. Through its focus on advancing The Consortium's mission, American Airlines is also on the path to realizing one of its most pressing goals. "We're working to restore our company as the greatest airline in the world and can only do that with employees who are as diverse as the customers we serve," says CEO Doug Parker. "So we must work to recruit, develop, retain and engage the very best people — those with unique perspectives and ways of thinking who can help us become the global leader we're poised to be. Leaders of the company are then accountable for cultivating an inclusive work environment that helps unleash all of our employees' potential, celebrating everything that a dynamic workforce has to offer."
ChampionX
ChampionX is a global leader in upstream and midstream oilfield technology solutions, digital offerings, chemistry programs and services. ChampionX has a rich history built on over a century of experience — dating back to the petroleum industry's infancy. With nearly 7,000 personnel globally, including 400 scientists and technologists in 60 countries, ChampionX is trailblazing technologies to support the industry's net-zero emissions goals and seeking the workforce to do it. "As an advocate, we are committed to expanding The Consortium's mission of diversity and inclusion in our workplace," a company representative said. "Through our membership, we hope to build a diverse pipeline of talent for leadership roles now and in the future at ChampionX."
Innosight
Honored to support The Consortium's mission, management consulting company Innosight hopes to use the opportunity to work toward achieving its own. "To fulfill Innosight's own mission — empowering forward-thinking organizations to navigate disruptive change and own the future — we know that we need to draw on the strengths of people from all backgrounds and experiences and empower our employees to achieve at their highest potential," a company representative said. "By partnering with The Consortium, we hope to accelerate our ambition to build a more diverse and inclusive team, while also learning and growing as an organization."
Empowered by recent nationwide events, fintech company Intuit has focused on accelerating its efforts to ensure it is delivering on its commitment to diversity and inclusion. Partnering with The Consortium is one way Intuit is working to meet its goal of increasing the representation of underrepresented minorities to 18 percent of its U.S.-based workforce by FY 2024. "Diverse representation is a key step in creating an inclusive and equitable environment where all employees can do the best work of their lives. Without representation, we cannot deliver for customers and achieve our mission," says Gabrielle Woody, university talent attraction manager. "To make meaningful strides in representation, we're increasing the aperture for recruiting to ensure we're employing diverse talent across every level of the organization."
Social media company Snap Inc. joined as a Consortium partner this year with the goal of strengthening its workforce. "The Consortium provides us with an opportunity to maximize our diversity recruitment efforts and build a strong workforce that ultimately reflects the market available talent pool," a company representative said.
To Xcel Energy, a partnership with The Consortium means the ability to attract innovative, diverse and exceptional talent to help achieve sustainability goals. As a trailblazer in energy innovation, Xcel Energy's vision is to provide 100 percent carbon-free electricity by 2050. "Xcel is leading the clean energy transition, promoting renewable energy, enhancing our customer experiences, keeping bills low and giving back to our communities," a company representative said. "We understand the importance of harnessing energy from top individuals with diverse perspectives. Xcel Energy supports the mission to enhance diversity within the utility industry and across the energy sector. A partnership with The Consortium is key to recruiting, retaining and promoting top talent across the vibrant careers that our company offers."
STEP Level
New Balance Athletics Inc.
New Consortium corporate partner New Balance believes in the power of diversity to drive success and is using the partnership as a means to do so. "At New Balance, we believe in promoting a culture that supports awareness, learning and the open exchange of ideas with our colleagues. Ensuring diversity in global business education and leadership gives more companies like ours the opportunity to benefit from different perspectives and achieve long-term success," a company representative said. "We recognize the value diversity brings to our personal experiences, to our work, to the products we create and to the events we produce. Fostering an environment of inclusivity and belonging is part of our cultural fabric and plays a critical role in our ability to live up to our standards of excellence, and achieving our growth objectives requires access to the best possible pool of talent."
Ocean Spray Cranberries
With a belief in the power of diversity, equity and inclusion, Ocean Spray partnered with The Consortium to create meaningful opportunities for people who have historically been underrepresented in business education and leadership. "The Consortium's mission is one that all organizations should look to support and advance. The systemic barriers that have led to the underrepresentation we see today can only be broken down if we strive for equity, inclusion and the advancement of people of color," says Alice Monteiro, talent acquisition and DEIA manager. "We are proud to lead alongside The Consortium in creating opportunities and cultural environments where people of color can lead and thrive. It makes Ocean Spray, and businesses like ours, better and stronger."
Reckitt is the consumer packaged goods company behind brands such as Lysol, Mucinex, Airborne, Airwick, Enfamil and Durex, which exist to protect, heal and nurture in Reckitt's relentless pursuit of a cleaner, healthier world. Beyond that, the company is leading the fight to make access to quality hygiene, wellness and nourishment a right and not a privilege. Reckitt's products fall into three categories: Hygiene, Health and Nutrition. The company joined the Consortium in 2021 with the intention of supporting its commitment to inclusion and representation, which supports Reckitt's leadership behaviors and shape the future of the organization. "At Reckitt you will have the #FreedomToSucceed," a company representative said.
With the goal of creating better products and experiences for consumers, video game company Ubisoft launched a partnership with The Consortium this year. "A core pillar of Ubisoft's company culture is to provide an open and respectful environment with diverse talent from different backgrounds, beliefs, gender identities, sexual orientations, abilities and geographical locations whose skills and individual qualities complement each other," says Ashley Swisher, HR program manager. "This partnership with The Consortium, and its mission to increase the representation of African Americans, Hispanic Americans and Native Americans in global business management, will support our goal of bringing more diverse voices to our teams in order to create even more memorable and enriching entertainment experiences."
Also joining The Consortium this year were AstraZeneca, Chewy, Gilead Sciences, Hilti and Loomis Sayles.
CGSM Staff | December 9, 2021
Simon Alumna T'Keyah Andrews Shares How her Mental Health Struggles Transformed her MBA Experience and Life
For T'Keyah Andrews, the MBA experience taught her far more than she could have ever imagined. Although she never envisioned graduating from a top-tier institution — let alone, at the age of 27 — she found herself joining The Consortium's…


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Galway Rural Development Invitation to access a Homework Support Programme in Galway
Galway Rural Development - Wednesday, June 22, 2016
GRD are currently the lead on the County Galway Integration and Diversity Strategy (2013-2017). As part of a new initiative, GRD is now inviting applications from suitably qualified organisations/schools, with experience of working with children at risk of early school leaving but particularly those from the Traveller and minority ethnic communities, to access a PILOT Homework Support Programme in County Galway in 2016.
GRD Commitment:
- GRD will manage the programme in conjunction with the steering committee.
- GRD will employ one Home-work Club Co-ordinator per project supported. These will be employed for a maximum of 8 hours per week (to allow for four afternoons per week with 1 ½ hour homework club and ½ hour preparation time each day)
- GRD will liaise with relevant parties to ensure that the children most in need are targeted.
- GRD will draw up a service level agreement to support the successful implementation of the programme in each area.
Requirements for involvement:
- The organisation/school should have a proven track record of dealing with travellers/ethnic minorities and have a strong community development ethos
- The organisation/school must have access to a suitable venue and cover the costs of heat/light and electricity
- The organisation/school will be responsible for their own insurance
- The organisation/school must undertake to provide a healthy daily snack
- The organisation/school will be responsible for the provision of additional support staff if necessary.
- All parties involved will adhere to the relevant Child Protection Polices
- The organisation/school will report on activities and outcomes to Galway Rural Development
- The organisation/school will become part of the steering committee for the Home work club
Please complete the application form via the link here: Application to participate in Homework Support Programme
Return to Breda Coyle, Education Officer, Galway Rural Development Co. Ltd., Mellows Campus, Athenry, Co. Galway or bcoyle@grd.ie no later than 5pm on Friday 8th July 2016.
Further information can also be sought from Breda Coyle at bcoyle@grd.ie
Note: The implementation of this project is subject to availability of funding.


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This month marks the 21st anniversary of the first Moor Laser Doppler Imagers to ship; a product that has helped to define Moor Instruments as a world leader in microvascular assessment. Over the years, LDI has helped fuel the growth of our business and enabled development of the new product ranges offered today.
Laser Doppler Imaging revolutionised research into the dynamics and spatial variations of the microvasculature by providing quantitative colour coded images of microvascular blood flow without contact. It has enabled a number of routine applications, from Clinical Burn Assessment to Angiogenesis Modelling (critical to wound healing and cancer suppression drug development and stem cell therapy research).
21 Years on, Moor is the only global provider of laser Doppler Imagers. We recognise that LDI maintains important advantages over newer technologies (such as laser speckle –also available from Moor).
First – the penetration depth. The algorithms used together with a focussed beam or laser line directed to the tissue penetrates further than blanket illumination used in laser speckle. This allows visualisation of tissue beds that are further below the surface than laser speckle. In the hind limb model for example, this allows clear visualisation of the femoral artery and collateral vessel formation that cannot be clearly seen with laser speckle.
Second – large area capability. LDI is the only technique to offer a single image up to 50 x 50 cm. That is particularly useful for clinical burn assessment where large area burns can be quickly assessed with a single image, rather than trying to patch together a map of 4-5 smaller image files that laser speckle would offer.
Thirdly – scan duration and resolution. This is an area where laser speckle has a clear lead and those features fit certain applications exceptionally well – we offer our own laser speckle option, moorFLPI2 in these cases. However, the unique LDI technology patented and still used today in our laser Doppler imagers (continuous moving beam technology) has always allowed us to generate "upper torso" images that are clinically useful from just 40 seconds– a small part of the overall assessment time when considering the full work flow. Using Laser Doppler line scanning (LDLS) will result in much quicker scans (albeit smaller), from just 4 seconds.
Finally – we are the only company to have undertaken rigorous multi-centre clinical trials and secured regulatory approval which allows us to offer the only medical device (of any kind) for clinical diagnosis of Burns.
We have continuously refined laser Doppler Imaging for 21 years based on the technique pioneered originally by Tim Essex and Byrne of Newcastle – the current product is now in its sixth generation and we are pleased to continue this support for applications where LDI is still preferable and useable.
We will also support and develop the newer laser speckle technique, continuing our tradition of adding application-specific functions for better data acquisition and extensive utilities for image analysis.
So here is to the coming of age of laser Doppler Imaging – Many Happy Returns!
Contact us to discuss your application in confidence and to set up a demonstration – we are always happy to advise.


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The Dissent Of Man
By JF Derry
A book exploring the influence of Darwin on everyone
Three Ducks
Apologies if you were hoping for an insightful examination of Anatidae (ducks, swans, geese, waterfowl per se), but the titular 3 ducks refer to the third week in a row with no pledge on the book. But, hey, what's 21 days out of the 1524 days that have elapsed since launch date? 1.3779528% to save you reaching for the calculator. Now, some crowd-funded authors might be reaching for the gin or Ginza (catalogue of Samurai sword specialists Ginza Choshuya), or both, however, I am a very patient person. Thinking in evolutionary time has that effect. So, to help you reach the same karmic peace in awaiting D-Day (that's Darwin Day, not Duck Day), here is a snippet from a previous book "what I wrote". Because I'm cheating by taking already written writing, you could call this, a nick of time. (Or not).
Anyway, pour yourself a nice long steaming hot bath of ice cold bubbly, kick back and set your book reading robot to it's Max Relax setting (anywhere between Kathleen Turner and Richard Burton), and enjoy this lesson in gradualism,
Scottish Geology
How slow ye move, ye heavy hours (Rab Burns)
The rate of change has always been central to evolutionary theory: slow gradualism versus abrupt saltation (from the Latin saltus meaning 'leap') in its several forms. Darwin's own understanding in gradualism came out of his appreciation of geological time and Earth's grand old age, and again Edinburgh features large in the history of this revelation. Edinburgh-born James Hutton was fascinated by local rock formations encountered on travels throughout Scotland, to Galloway, Arran, Jedburgh, the Cairngorms, famously at Siccar Point near Berwick-upon-Tweed, and also right within the capital, in the Salisbury Crags on Arthur's Seat. Hutton just couldn't connect what he was seeing with Abraham Werner's widely accepted Neptunism (Neptune, god of water and the sea in Roman mythology) which held that rocks had sedimented out of ancient flood waters, that some Neptunists, such as Robert Jameson, interpreted to be the biblical flood.
Instead, Hutton proposed a naturalistic Plutonist (Pluto, god of the underworld) argument that rock was produced from a molten Earth's interior and manipulated and mixed and eroded over a great period by forces, into the formations that he had observed. Not least, he surmised that those processes must be ongoing, giving rise to an attitude of uniformitarianism, the constancy of processes. Hutton's friend John Playfair, and companion to Siccar Point, recalled that 'the mind seemed to grow giddy by looking so far into the abyss of time'. Suddenly the Young Earth based on biblical time and catastrophically sudden developments was insufficient to accommodate the evidence for these gradual processes, and the vital concept of 'deep time' was born, or at least reborn, given that the Chinese polymath Shen Kuo (1031– 1095) had first recognised the gradual process of sedimentation in the 11th century.
Darwin absorbed Hutton's influence, especially regarding the continuity of nature and the true antiquity of the earth. His own formal geological training did little to instruct him in the core concepts. Attending Robert Jameson's courses during the second year in Edinburgh he should have been stimulated by lessons on stratigraphic geology, learning about the studies of Georges Cuvier (1769–1832) with mineralogist Alexandre Brongniart on the geology around Paris, which formed a direct precursor to the ageing of rocks and the dating of fossils. Instead, he found the lectures so 'dull' that '[t]he sole effect they produced on me was the determination never as long as I lived to read a book on Geology, or in any way to study the science'. In later years, he referred to his Neptunist professor as 'that old brown, dry stick Jameson', and reflected that he
heard Professor Jameson, in a field lecture at Salisbury Craigs, discoursing on a trap-dyke, with amygdaloidal margins and the strata indurated on each side, with volcanic rocks all around us, and say that it was a fissure filled with sediment from above, adding with a sneer that there were men who maintained that it had been injected from beneath in a molten condition. When I think of this lecture, I do not wonder that I determined never to attend to Geology.
Although Jameson's course did nothing to inspire the young man, perhaps it did seed in Darwin a title for the Origin of Species,1 and it also brought immediate benefits in giving him a chance to help with the collections in the University Museum, where he became an assistant and was awarded desk space. Tending the collections would have provided a flashback to his indiscriminate collecting as a childhood hobby, a status not radically different from that of the post- pubescent scientific amateurs who dominated British geology throughout this 'heroic age', until the founding of the British Geological Survey in 1835. The Survey formally made professionals of these gentlemen geologists. Jameson himself was a doctor by training who had been inspired into geology by John Walker (1730–1803), his Professor of Natural History at the University of Edinburgh from 1779 until 1803, and previously 30 years a Presbyterian parish priest – perhaps understandable, then, Jameson's biblical interpretation of Werner's flood, although, years later, he was to change his outlook in favour of Hutton.
Hutton's geological 'deep time', popularised by Lyell, and which could accommodate gradual evolution by natural selection, was hotly contested by William Thomson, later 1st Baron Kelvin (1824–1907), a mathematician and engineer at Glasgow University. Thomson had contradicted uniformitarianism by using thermodynamics to calculate the age of the sun, and the subsequent cooling time of the earth, to be insufficient for evolution to have occurred: 'I may say, strenuous on this point, that the age of the earth is definite. We do not say whether it is twenty million years or more, or less, but we say it is not indefinite. And we can say very definitely that it is not an inconceivably great number of millions of years... is earth, certainly a moderate number of millions of years ago, was a red-hot globe'. Unfortunately, Thomson had omitted nuclear fusion and radioactivity from his calculations, and so the potential for a star to burn bright for billions of years. e capacity of the earth to generate its own heat, thereby appearing younger than reality, had escaped him, but understandably so, as this was not known until the early 20th century.
Meanwhile, in the absence of this knowledge, Darwin was concerned by Thomson's calculations inasmuch as he estimated a longer period necessary for evolution before the Cambrian than afterwards. is much he confessed to James Croll (1821–1890), self-taught geologist and expert on glaciers who was appointed Resident Geologist and keeper of maps and correspondence at the British Geological Survey offices in Edinburgh from 18672: 'I am greatly troubled at the short duration of the world according to Sir W. Thomson, for I require for my theoretical views a very long period before the Cambrian formation'.
Thomas Henry Huxley (1825–1895), 'Darwin's bulldog' and Acting Professor of Natural History at the University of Edinburgh from 1875 to 1877, attacked Thomson, calling to doubt his information sources: 'Mathematics may be compared to a mill of exquisite workmanship, which grinds your stuff to any degree of fineness; but, nevertheless, what you get out depends on what you put in; and as the grandest mill in the world will not extract wheat flour from peas cods, so pages of formulae will not get a definite result out of loose data'. However, Darwin had little recourse other than to maintain his convictions, foremost in his own powers of deduction: '[P]re-Silurian creatures must have lived during endless ages else my views wd be wrong, which is impossible – Q.E.D.'; and then also in Lyell's methods, about which he admitted to having insufficient understanding of the appropriate mathematics, 'which profound ignorance gives, but I cannot help observing that when applied to uncertain subjects, such as geology, it gives as uncertain results as geologists arrive at by other means; for instance, how Thomson and others differ about the thickness of the crust of the earth and the rate of cooling'. But, on this subject, Croll was qualified to comment:
I think that you may quite fairly assume a very long period before the Cambrian formation, even according to Sir William Thomson's theory; for, supposing the earth to have originally been in a molten condition, a solid crust would very rapidly form, and if this crust would not break up and sink, the globe at the surface would be cool and suitable for life, although a short way down below the surface the heat was intense. This results from the slow rate at which the crust is able to conduct the heat from within.
Thanking Croll ('It is consolatory to me that you are inclined to give a little more age to the world'), Darwin reveals that Croll's contributions helped him to maintain confidence in his work, and reinforce his armour against his other critics.
1st edition hardback
ebook edition and your name in the back of the book


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A Q&A with Kelly Holstine: on advancing educational equity for LGBTQ students
After 12 years of teaching, the 2018 Minnesota Teacher of the Year switched to advocacy work to further expand her impact.
Kelly Holstine: "I'm still an educator — it's just that my classroom got bigger."
MinnPost photo by Erin Hinrichs
Riding a wave of celebrity that came with the designation of 2018 Minnesota Teacher of the Year, Kelly Holstine still honors requests for local keynote addresses. She also fits in travel to fulfill her national duties as a state Teacher of the Year, which extend through 2019.
Last week she delivered a Ted Talk in New York and addressed educators at the MEA conference back home. Then she scheduled a classroom visit for Monday with an English teacher who'd invited her to model a lesson on teaching students about pronouns.
In her new role as director of educational equity for OutFront Minnesota, an LGBTQ advocacy group, Holstine will continue to spend time in the classroom. She'll also spend time helping educators create more inclusive learning environments — by doing things like including LGBTQ authors in the curriculum, creating gender-neutral bathrooms, and asking students to line up according to their birthday month rather than by gender.
After 12 years of teaching, Holstine switched to advocacy work to further expand her impact. She has her sights set on improving school climate and outcomes for some of the state's most marginalized students: LGBTQ youth.
According to the 2019 Minnesota Student Survey, LGBTQ students are three times as likely to say they've seriously considered attempting suicide and four times as likely to attempt suicide as their heterosexual peers. Transgender students in the 11th grade are the most likely to attempt suicide. And 42 percent of these students say they have attempted suicide, compared to 9 percent of their cisgender peers in the same grade.
Ahead of the new student survey release, MinnPost sat down with Holstine at her office in Minneapolis to learn a bit more about her own experiences navigating the education system as a gay student-turned-teacher, and about her new efforts to improve school safety and mental health for LGBTQ students across the state.
MinnPost: Do you think you're better suited to support LGBTQ students in your current role?
Kelly Holstine: I don't know if it's better or worse. I think it's different. As a teacher, I was able to directly support individual students and groups of students. At the two mainstream schools I was at before Takota Learning Center, I had GSAs (Gender and Sexuality Alliances) — so I was able to provide support groups for students. And at Takota, every day we would have flex schedule, where we could have sessions with different titles, and I would try to lead sessions related to LGBTQ students. Now, I'm still an educator — it's just that my classroom got bigger. I'm able to help support educators with their work with LGBTQ students: how to be there for those folks, how to answer questions, how to provide support, how to start GSAs, and how to include LGBTQ curriculum.
MP: How do you approach this work in a way that doesn't overwhelm …
KH: … my spirit? I've been here three months. So I do think I'm still trying to figure that out. But I definitely have a vision that I'm trying to follow — which is to involve all of the stakeholders in the process: policy makers, administrators, superintendents, school boards, educators, students, paras. And we have a youth advisory council. It's definitely not a small task. But I feel excited at the opportunity to try and make schools safer for our LGBTQ humans — both educators and students.
MP: How do you build inroads in school communities where you know there's an unmet need that LGBTQ students have, but the community isn't as receptive?
KH: I think it's starting with the folks in those communities who are ready and who are looking for that support, because sometimes they might be just one, or be one of a few. I have noticed that some districts feel more comfortable having me come in as Teacher of the Year — so trying to build those relationships and helping educators see I'm not coming in with a desire to judge or to put people down or to question their past behaviors. I get that there has to be that level of safety there. It's vulnerable to not always be the expert in something. And it's vulnerable to have to learn something that's new to you.
MP: Can you give an example? When you are inside a school, what's a common training that you do?
KH: There's the LGBTQ+ 101 and intersectional equity training. It's a 90-minute training with educators, school boards, administrators — whoever wants to come to the table. It's teaching concrete strategies about how to make classrooms in schools more LGBTQ+ inclusive. It's also teaching terms about identities and orientations. So we're going over specific terms. But we're also taking some time to process that to process: What does gender mean for us as individuals, for kids?
MP: Do you care to share a bit about your experiences as a student, growing up?
KH: I was a tomboy as a kid. I'm from a small community in southern Minnesota. And I got picked on a lot. I had some really supportive teachers and some supportive friends, but there were some folks that were afraid of things they didn't understand. And so I got bullied quite a bit — kicked and beat up and spit on and called names. That was tough. So teachers are the ones who made me feel safe. I'm sure that contributed to my desire to want to create such a safe place for kids.
In high school I wasn't allowed to be a tomboy anymore. My parents decided that wasn't an option. So I had really long, curly, blonde hair and was super feminine looking. So my external was feminine and the bullying decreased. But my depression increased. And that was really a difficult time for me — to be in feminine drag and to not identify with that as an external gender expression.
I went to college. My freshman year, one of my best friends came out as gay. So I became an ally and learned everything I could to support him. Sophomore year, I was in Ireland on a J-term, looking out over the Cliffs of Moher, and I had that "ah-ha" moment. I realized that I had a crush on someone on the trip. It was like all of these puzzle pieces connected at that moment. Everything made sense. The next day we were in Galway and I got my hair cut short, and started wearing glasses, stopped wearing makeup. I was playing this part and then I got to be me again.
MP: So that's always been a part of who you were, as an educator, as well?
KH: I took an education class in college and actually did very poorly in the class because it was an elementary ed class that was all multiple choice tests. Also, it took me so long to figure out my orientation and then to be out. What I was hearing is it was really hard to be an out teacher. I was thinking: "I can't go back into the closet. I just can't do it." So I ended up majoring in communications and worked in TV and media. Then I got into social services. Then in my 30s I was working in the field of child sexual abuse. After doing that for a couple of years, I started to feel like it really impacted my hope — to hear those stories and feel that pain these kids were feeling. I wanted to be part of the whole picture. I wanted to do more preventative work. That's when I decided I was ready to be an out teacher. So I went back and got my teaching license in communication arts and literature.
MP: As a teacher, you advised a couple of GSAs. What are the sorts of things these student groups are doing in schools that are so impactful?
KH: It used to be the GSA was the Gay-Straight Alliance. Now it's the Gender and Sexuality Alliance. And some people call themselves SAGA — which stands for Sexuality and Gender Alliance. There could be social components. Making sure that folks don't feel isolated is really, really important — and that they feel supported, understood, that they feel that their identity is not just tolerated, but celebrated. When I was a GSA leader, we'd go roller skating, we went to the Pride parade. Some LGBTQ students feel, depending on where they live, that some of those social opportunities are more challenging if you're one of the only ones. There's a group that does a queer prom. OutFront, with the help of other organizations, puts on an event called Youth Summit in the spring and we meet with legislators. There are a lot of GSAs interested in policy work.
MP: How else are you working to improve school environments for LGBTQ students?
KH: I know of at least five districts that have passed a gender inclusion policy (ISD 622, St. Paul, Minneapolis, St. Louis Park and Richfield). I'm really hoping to support districts in that work because just having a gender inclusion policy communicates to your students that you want to provide a safe environment for them to learn. It's education around policies. It's support around how do you help your students who are being bullied. It's support around how do you help your students who are figuring out who they are? It's support around adding LGBTQ curriculum so kids can see themselves in the curriculum. It's support around helping teachers work with their own implicit and explicit bias, so students don't feel they're being discriminated against. It's working with curiosity over judgment. There's a lot of work to do and a lot of support that I'm hoping our program can give.
MP: Are there less publicized LGBTQ issues that you want to flag?
KH: I think graduation rates. We're not tracking that right now. We are tracking it for race, and Minnesota has one of the worst opportunity gaps in the nation. It's hard to track, because not everyone's going to disclose. But I would guess that the graduation rate for LGBTQ kids is also really low. That's a huge issue. If you don't have your high school diploma, you're very limited in your options. Also, there are five states now where it's mandated that teachers have to include LGBTQ curriculum. I would love Minnesota to be one of the next ones. What that means in these states is that teachers have to include LGBTQ folks and history in their curriculms. If you're in a history classroom and you're talking about American history, you're also gonna talk about the LGBTQ movement. In English class, you're going to have authors and characters who are LGBTQ. In health ed and sex ed, you're also going to be talking about what that means for people who are LGBTQ.
MP: Is there anything else you wanted to talk about, or let folks know about?
KH: I just think it's really helpful for folks to realize that they have LGBTQ people in their life, even if they don't realize it, especially in school. You have LGBTQ students — statistically, at least 10 percent. You have LGBTQ educators in your school. My hope is that we can get even more folks to accept and celebrate people that are already in their community — as a way to decrease isolation, increase opportunities for students and teachers to thrive. My definition of educational equity is finding out what students need academically, social-emotionally and everything in between and getting it for them. And that's what this is about for me: educational equity. And it's skills building. If you can learn how to do that for folks who are LGBTQ, then you are going to be better at it with folks from different races and cultures, and with kids with disabilities and mental health issues.
Erin Hinrichs
Erin Hinrichs is MinnPost's education reporter. She can be reached at ehinrichs@minnpost.com, and you can follow her on twitter at @Erin_Hinrichs.
How COVID-19 has interrupted — and modified — teacher licensure in Minnesota
How Minnesota school leaders are advancing equity work in a shaky back-to-school environment
Minnesota's social studies standards are up for review — and BIPOC committee members seek major reforms
More Education articles


Early voting begins on Saturday and runs through March 23 for the March 30 primary election.
From 8:30 a.m. to 6 p.m. daily — except Sundays — voters can go to the Covington Office of Voter Registration at 601 N. Jefferson Ave. or the Slidell Office at 520 Old Spanish Trail. The Mandeville office at 21490 Koop Drive will be closed for the election.
Identification is required to vote. For more information, call (985) 809-5500 or (985) 646-4125.
The major stakeholders in Louisiana public education have joined forces to co-host a series of town hall meetings over the next several weeks.
The Louisiana Public School Coalition includes the Louisiana Association of Educators, Louisiana Association of Principals, Louisiana Association of School Superintendents, Louisiana Federation of Teachers, Louisiana School Boards Association and Louisiana Retired Teachers Association.
The coalition collectively represents the interests of tens of thousands of education professionals, paraprofessionals, employees, lawmakers and retirees, and plans to host 11 meetings across the state through April 4.
The town halls will spur solutions-oriented discussions with legislators and members of the public on funding, teacher/employee pay raises, and recruitment and retention of teachers.
Keep Slidell Beautiful will hold its spring citywide cleanup and beautification day from 9 a.m. to 11 a.m. on April 6 at Heritage Park. After the cleanup volunteers will meet back at Heritage Park for a pizza luncheon and will receive KSB T-shirts.
Volunteers are needed to help plant flowers in gardens around the city as well as pick up trash in certain areas.
For more information about the cleanup, go to www.keepslidellbeautiful.org.
The St. Tammany Democratic Executive Committee has gained four new members.
At its Jan. 28 meeting, it elected Lynne Craven, of Covington, to represent District 1, and Robin Schulberg, of Covington, to represent District 6. At its Feb. 25, meeting, it elected Gertrude Ivory, of Slidell, to represent District 14, and Jim Francis, of Covington, to fill an at-large seat left by former member Jim Harlan.
Craven has lived in Covington with her husband for seven years. She runs a video production company and recently ran for the St. Tammany Parish School Board in District 2.
Schulberg is a retired attorney who clerked for U.S. Circuit Judge Henry A. Politz, taught at Tulane and Loyola law schools, and served as an assistant federal public defender. She lives on a small farm in north-west St. Tammany.
Ivory is an educational consultant who works with the Louisiana Children's Museum. She also serves on the board of Lantern Light Ministry.
Francis ran for U.S. Congress in 2018 to represent the First Congressional District and lives in Covington with his wife Nicole and their son, Cooper. He runs his own consulting and software development company and builds custom guitars in his free time.
The St. Tammany Democratic Executive Committee represents the parish's Democratic voters and works to spread the Democratic message, uphold progressive values and elect Democrats to office.
Mayor Mike Cooper has announced that for the seventh consecutive year the Certificate of Achievement for Excellence in Financial Reporting has been awarded to the City of Covington by the Government Finance Officers Association of the United States and Canada (GFOA) for its comprehensive annual financial report (CAFR). The Certificate of Achievement is the highest form of recognition in the area of governmental accounting and financial reporting, and its attainment represents a significant accomplishment by a government and management.
"The City of Covington is tremendously proud to once again be recognized as a recipient of this prestigious award. I, and members of the Covington City Council, wish to acknowledge and commend Chief Administrative Officer Gina Hayes and Finance Director Alisa Faciane for their adherence to the best financial practices. They are an asset to our City and to my administration. My thanks are also extended to the CPA firm of Carr, Riggs & Ingram, who formally submitted the annual financial report on the City's behalf," said Mayor Cooper.
The GFOA is a nonprofit professional association serving approximately 19,000 government finance professionals with offices in Chicago, IL and Washington, DC.


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Capitalist Modernity in Crisis
In the 21st century, humanity finds itself in an unprecedented systemic crisis. Whether the ecological catastrophe, the escalation of wars, the political crisis of parliamentary democracies, or the global advance of nationalism and fascism, they are all expressions of the deep crisis into which Capitalist Modernity has plunged humanity and nature. The capitalist system, with its boundless pursuit of maximum profit and ruthless exploitation of people and nature, continues not only to trap billions of people in poverty and misery, but is today in the process of destroying our ecological basis of life. Climate change, overexploitation, the displacement of a natural-social way of life, and the inexorable destruction of habitat, especially indigenous peoples, are just a few indications of a large-scale collapse. Social isolation, the disintegration of social structures and the downward transfer of the consequences of the crisis are leading to a worsening of the crisis and the rapidly increasing impoverishment of a large part of humanity.
Instead of developing solutions to the most pressing problems of humanity, the established social sciences are incapable of finding answers to social questions and all too often degenerate into a prop of the ruling system. The social sciences produce and reproduce ideologies and ways of thinking that significantly shape social conditions, coexistence, our culture and way of life. However, instead of seeking radical solutions and a way out of the crisis, the social science enterprise has contributed greatly to the legitimization of patriarchy, racism, and capitalist exploitation through its theories and applied methodology over the past two centuries. Since the dominant scientific enterprise is both theoretically and methodologically intertwined with power, and in many ways dependent on the dominant system, there is an urgent need for a radical critique of the existing social sciences, as well as new methodologies and institutions with a different perspective.
The crisis of the democratic forces
The capitalist system is also trying in vain to find a way out of its desperate situation. Not least the doomed "green capitalism" makes it clear that there can be no solution whatsoever within the logic of the existing system. Any attempt to reinvent the old system can perhaps delay the impending collapse, but it cannot point to a way out of the crisis. What makes this hope for betterment with the old dangerous is the associated perpetuation of the given state of crisis.
The growth of new feminist, ecological, anti-colonial and democratic movements must be understood as a reaction to the general systemic crisis. But their current theoretical and practical situation feeds doubts about their ability to build an alternative to the existing system. The democratic forces either strive for power themselves and are increasingly absorbed by the system, or they leave the political sphere untouched and thus cannot form a practical alternative. In order not to fall under the influence of neoliberalism, a real opposition to the system and a radical moral, political and intellectual renewal are needed.
A Way Out of the Crisis: Democratic Modernity
The assault of Capitalist Modernity against society makes the alternative of Democratic Modernity a compelling necessity. In doing so, we can look back on a rich intellectual and scholarly heritage of revolutionary awakenings, ranging from utopian and scientific socialism, anarchism, the Frankfurt School, French philosophy of the second half of the twentieth century, anti-colonial liberation struggles, to the awakenings of the new left, the feminist and ecological movements beginning in the 1970s, and the emergence of postmodern schools of thought since the 1990s.
The perspective of Democratic Modernity, developed by the Kurdistan Freedom Movement, also builds – among many others – on these experiences and represents today a concrete response to the prevailing capitalist patriarchy. The paradigm of Democratic Modernity, with its three pillars of radical democracy, women's liberation and ecology, is not a concept that is relevant only to the societies of Kurdistan and the Middle East, but far beyond. The experience of the revolution in Kurdistan has helped democratic and socialist forces worldwide find new orientation and inspiration in the paradigm of democratic modernity. The successes of social self-organization in democratic confederalism have renewed hope and faith in the possibility of a world beyond the current capitalist one.
Based on the realization that a solution can only become possible through the development of our own system as an alternative to the three pillars of capitalist modernity – capitalism, industrialism and the nation state, we think it is time to deepen these discussions and take the necessary steps towards organizing and building. The Democratic Modernity, based on a democratic society, an ecological industry and the political system of Democratic Confederalism, we understand as the counter-system to be built.
The Construction of Democratic Modernity
The intensity of the crisis of Capitalist Modernity is noticeably increasing for people worldwide and the rejection is growing. The question of alternatives is now being raised and discussed in broad circles. From our analysis of the world political situation, we understand that global resistance is growing and the construction of democratic alternatives is advancing. In the mass protests and uprisings of recent years, the reawakening of a global women's movement, the young climate justice movement, the protest movements against racism and white supremacy, and also the mass strikes in industry and agriculture, especially in the global South, Democratic Modernity is becoming tangible and taking shape in the global awakening of humanity. The old world and the new world, Capitalist Modernity and Democratic Modernity already exist side by side and intertwined. However, while the Capitalist Modernity is a highly organized and global system, the alternative remains to this day disorganized, fragmented and without a strategic and unifying proposal of common organization. As Academy of Democratic Modernity, we see our task in building Democratic Modernity, in educational work to create a new understanding of democratic politics, social enlightenment and a new political-moral consciousness, which are the foundations of a free society. At the same time, we consider the creation of new networks and connections between democratic forces as a fundamental prerequisite for the construction of Democratic Modernity. Through the creation of forums and platforms, we want to contribute to the strengthening of the international exchange of experiences and connect existing struggles.
Our work includes the following three areas:
Social education work – spreading and discussing the paradigm!
The social education work of the Academy of Democratic Modernity is oriented towards the aim: rethink, reexamine and build new institutions! In order for the social sciences to contribute to the development and implementation of social, political and economic alternatives, they must free themselves from material and ideological dependence on the system and see themselves as part of the resistance against capitalist modernity. For autonomous educational work, the establishment of independent academies is a prerequisite. Their task is to contribute, according to social needs, to the development of a society based on radical democracy, ecology and women's liberation. All scientific work must be carried out by and for the moral and political society. We want to provide a platform to discuss approaches to local problems as well as the fundamental contradictions of the prevailing system. Just as fundamental social change is inconceivable without building the necessary organization, organization is nothing without a coherent and solid theoretical foundation. It is therefore necessary to intensify the critique of the existing, to think alternatives, to educate ourselves and to organize ourselves.
Connect democratic forces – create networks and learn from each other!
Starting from the situation of the democratic forces, we consider it our strategic task to connect the existing struggles and to create global networks of exchange and solidarity. Through exchange of experiences and dialogue we want to create mutual understanding and collective consciousness. In doing so, we aim to overcome ideological divides and bring our shared values and interests to the forefront. We want to create an awareness of the historical and global interconnectedness of all struggles against exploitation and oppression in order to help our struggles worldwide gain new strength. In order to break through the powerlessness, we must learn to think and act socially and thus unite the various social and ecological struggles. Today, more than ever before, the solution to the most urgent problems of humanity requires the creation of global platforms and structures. The ecological catastrophe alone makes it clear that individual isolated local approaches to solutions are doomed to failure. Only the connection of local work with a global perspective can open a way out of the crisis.
Concretize the alternative – build the Democratic World Confederalism!
For the unfolding of the democratic and overcoming of the capitalist modernity, concrete local and global institutional structures are also needed. In this sense we consider our activities as a contribution to the building of the Democratic World Confederalism. With the dissemination of ideas, the elaboration of a theoretical basis and the mobilization and networking of the existing organizational potential, we want to pave the way to build Democratic Modernity by means of permanent structures. If we succeed in expanding democratic politics in everyday life – through alliances, councils, communes, cooperatives, academies – the huge political power of society will unfold and be used to solve social problems. Through the expansion of democratic politics and the building of Democratic World Confederalism, the much-needed offensive of the paradigm of Democratic Modernity will succeed.
Let us work together to bring our visions and utopias to life. Another world is not only possible – given the world situation, it is sorely needed. Let us start building our future world together in the present, because to wait any longer would be madness.


text:
package com.wallace.spark

import com.wallace.common.LogSupport

/**
  * Created by huangbiyu on 16-6-7.
  */
object Boot extends LogSupport {
  def main(args: Array[String]): Unit = {
    val a: StringBuffer = new StringBuffer
    a.append("wallace").append(",").append("hello").append("!")
    log.info(a.toString)
  }
}

redpajama_set_name: RedPajamaGithub


text:
Times of San Diego
Local News and Opinion for San Diego
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New Claims Added in Wrongful Death Lawsuit For Woman Killed in La Jolla Crash
Home » Crime » This Article
San Diego Woman Sentenced to 70-Month Term for Ponzi Scheme
Posted by Debbie L. Sklar on December 9, 2019 in Crime | 539 Views
| Comments | Leave a Comment
Justice Department flag in Washington. File photo
A woman was sentenced Monday in Santa Ana to nearly six years in federal prison for operating a multimillion-dollar Ponzi scheme through two San Diego-based companies, in which investors were defrauded out of more than $6 million.
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Susan Margaret Werth, who pleaded guilty May 2 to wire fraud, was also ordered by U.S. District Judge James V. Selna to pay nearly $6.3 million in restitution to her victims, one of whom lost two-thirds of his savings and had to go back to work at the age of 72.
Another victim, who is 62, had to postpone her retirement when she lost $800,000, according to federal prosecutors.
Werth, 58, of San Diego, ran the scam out of Commercial Exchange Solutions Inc. and Exchange Solutions Company Inc., both based in San Diego, according to the U.S. Attorney's Office.
Werth and her subordinates solicited millions of dollars from investors with claims the money would be used to obtain short-term construction loans from other clients, who would use a method to defer capital gains taxes through a tax break for selling an investment property and using the proceeds to reinvestment in a similar property of equal or greater value, prosecutors said.
The defendant told investors that their investments were "risk-free" and completely guaranteed by her company's collateral, prosecutors said. Werth created bogus bank accounts that duped investors into thinking there was a balance of $7.2 million and sent them phony emails indicating she was an employee of the bank, prosecutors said.
The investors were promised a rate of return of at least 15%.
"In reality, Werth knew the representations were false and fraudulent because she operated CES and ESC as a Ponzi scheme, in which the vast majority of its incoming revenue was comprised of victim-investor funds, which defendant Werth used to repay prior victim-investors, to pay her personal expenses, to withdraw cash, to repay investors' principal, and to make fictitious profit payments to some investors," according to the U.S. Attorney's Office.
Werth's "conduct affected honest citizens who entrusted [her] with significant amounts of money, some, their retirement funds and savings," the prosecution's sentencing memorandum stated.
Last December, a default judgment was entered in a Securities and Exchange Commission lawsuit against Werth.
San Diego Woman Sentenced to 70-Month Term for Ponzi Scheme was last modified: December 10th, 2019 by Debbie L. Sklar
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Posted in Crime | Tagged Commercial Exchange Solutions Inc., Exchange Solutions Company Inc., Ponzi scheme, San Diego, sentenced, Susan Margaret Werth
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On April 23, 2017, in the Ferguson Ballroom on the University of Alabama's campus, the first annual Forza Financial High School Business Plan Competition was held.
Lawson Hill (Prop-Smith Cosplay) took home the $500 grand prize in the first annual Forza Financial High School Business Plan Competition.
Thirty-one students from Paul W. Bryant High School and The Capitol School registered for the competition to form a total of 11 teams. Each group wrote a business plan for a hypothetical or pre-existing company of their creation, which were graded by several employees in advance based on parameters designed by the Strategy Department. Participants then pitched their ideas in person on the competition date, which were graded by a panel of judges. The judges consisted of two professionals, Ms. Tommie Syx and Dr. Ying Qin, and several Forza employees including CSO Rick Lewis. Final scores were calculated by averaging each team's plan and pitch scores together.
Madison Horton (Xceptional Creationz) shows off her homemade cosmetics to the judges.
Lawson Hill of The Capitol School took home the $500 grand prize. Hill's company, Prop-Smith Cosplay, designs and creates custom costumes for comic conventions and similar events. Lawson started making his own costumes when he was in elementary school and recently turned his hobby into a profitable custom costume creation service.
Bee Box, a hypothetical company designed to sell portable beehives, won second place. With great energy and charisma, Tristion Gilmore, Griffin Fishel, and Maya Sample of The Capitol School explained how Bee Box would allow even amateurs to harvest their own fresh honey while helping the ecosystem at the same time.
Madison Horton of Paul W. Bryant High School took home third place with Xceptional Creationz, a company she created around an already existing hobby of selling homemade cosmetics. Madison showed two of her products to the judges: her rosewater spray and one of several lip glosses.
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text:
Griffith Theses
Theses - Higher Degree by Research
Delineating the overlapping roles of the single-stranded DNA binding proteins Ssb1 and Ssb2 in the maintenance of genomic stability and intestinal homeostasis
Nag, Purba_Final Thesis_Redacted.pdf (7.186Mb)
Nag, Purba
Primary Supervisor
Lopez Ramirez, Jose Alejandro
Khanna, Kum Kum
Other Supervisors
Bain, Amanda
Single stranded DNA (ssDNA) binding proteins (SSBPs), are known key players of DNA damage response (DDR) pathway and play an essential role in stabilising fragile ssDNA generated during DNA replication, transcription and repair. The canonical SSBP is the heterotrimeric Replication Protein A (RPA) which is involved in a number of key cellular processes including replication and repair via Homologous Recombination (HR) in the course of DNA damage. Our lab recently described two new SSBPs, termed SSB1 and SSB2 (also known as NABP2/OBFC2B/SOSS-B1 and NABP1/OBFC2A/SOSSB-2, respectively) which form independent co-complexes with ...
View more >Single stranded DNA (ssDNA) binding proteins (SSBPs), are known key players of DNA damage response (DDR) pathway and play an essential role in stabilising fragile ssDNA generated during DNA replication, transcription and repair. The canonical SSBP is the heterotrimeric Replication Protein A (RPA) which is involved in a number of key cellular processes including replication and repair via Homologous Recombination (HR) in the course of DNA damage. Our lab recently described two new SSBPs, termed SSB1 and SSB2 (also known as NABP2/OBFC2B/SOSS-B1 and NABP1/OBFC2A/SOSSB-2, respectively) which form independent co-complexes with two additional proteins, the Integrator complex subunit 3 (INTS3) and the chromosome 9 open reading frame 80 (C9ORF80), a small acidic 104 residue polypeptide. Previously, we demonstrated that whilst Ssb1/Nabp2 KO in mouse caused perinatal lethality, Ssb2/Nabp1 KO did not lead to any phenotypic abnormalities. Interestingly, ablation of Ssb1 led to stabilisation of Ssb2 and vice-versa, indicating functional redundancy between these two proteins. This was recently demonstrated in-vivo by the generation of Ssb1 and Ssb2 (together referred as Ssb1/2) double-knockout (DKO) mice, which caused early embryonic lethality in a constitutive model and acute bone marrow failure and intestinal atrophy using the inducible Rosa26-CreERT2 system. To delineate the functional redundancy between these two proteins at the molecular level, we have generated inducible DKO mouse embryonic fibroblasts (MEFs) using the Rosa26-CreERT2 system, which will be described in the first research chapter. We found that cumulative loss of Ssb1/2 in the primary as well as SV40-immortalised MEFs led to acute proliferation arrest and cell death following TAM administration. This was associated with accumulation of genomic instability via endogenous replication stress. Although loss of Ssb1/2 in-vivo and in-vitro is associated with accumulation of R-loops, the overall DKO phenotype was not able to be rescued with overexpression of RNaseH1, which resolves R-loops. Additionally, we investigated the roles of Ssb1/2 following treatment with different DNA damaging agents to determine their roles in the DDR system. Interestingly, DDR signalling in DKO was normal following ionizing radiation, ultraviolet C and camptothecin but with hydroxyurea treatment that causes replication stress, we observed a delayed signalling response in DKO. Together, this chapter defines the phenotypic changes that take place in-vitro when Ssb1 and Ssb2 are deleted. The second research chapter describes our finding that loss of Ssb1 and Ssb2 together leads to reduced levels of several Integrator components and thus, has an equivalent profound effect on the misprocessing of the Sm- associated small nuclear RNAs (snRNAs) to that of the Integrator catalytic components- IntS9 and IntS11. Here, we show that upregulated snRNAs are not only misprocessed, but extend up to several hundred to a thousand base pairs past their native termination site, and are polyadenylated. Additionally, we demonstrate that loss of Ssb1/2 led to changes in the dynamics of alternative splicing, likely due to perturbation of the splicing machinery by aberrant snRNAs. We further show that a number of regulators of transcription and the cell cycle are affected by these changes, which might contribute to the loss of viability observed in DKO cells. Together, these findings reveal the critical role of Ssb1/2 and their association with the Integrator complex in regulating cellular proliferation and spliceosomal function. The third chapter of this thesis further investigates the intestinal atrophy observed upon loss of Ssb1 and Ssb2 in the DKO mice from our lab. For this, we have generated a small intestine (SI) specific Ssb1/2 DKO mouse- the VillinCreERT2 Ssb1flox/flox; Ssb2flox/flox model. This mouse model is a unique system to study the undefined roles of Ssb1/2 in the small intestine (SI) by bypassing the confounding effects of the bone marrow phenotype in the ubiquitous Rosa26-CreERT2 DKO model. We have found that loss of intestinal Ssb1/2 leads to exhaustion of the stem cells in the crypts, resulting in loss of the normal crypt-villus axis anatomy which causes acute morbidity within six days of induction. Interestingly, the stem cells are pushed to proliferate immediately after the loss of Ssb1 and Ssb2, followed by the exhaustion of these cells. This is demonstrated by sequential proliferation studies using the known thymidine analogue 5-bromo-2'deoxyuridine (BrdU) as well as quantitative reverse transcription polymerase chain reaction (qRT-PCR). Therefore through this model, we have demonstrated a fundamental role of Ssb1/2 in the maintenance of intestinal homeostasis. In conclusion, through the inducible abrogation of two SSBPs- Ssb1 and Ssb2 together, we have demonstrated several novel roles of these proteins in the maintenance of genomic stability both in-vitro and in-vivo that were previously masked in single KO studies. Further, we have defined the molecular mechanisms underlying the acute lethality observed upon abrogation of these two proteins.
Thesis (PhD Doctorate)
Degree Program
School of Environment and Sc
https://doi.org/10.25904/1912/1437
The author owns the copyright in this thesis, unless stated otherwise.
Single-stranded DNA
Binding proteins (SSBPs)
Genomic stability
Molecular mechanisms


This week will be pretty hectic, so I am trying to get in as much blogging as I can, as I will be MIA next week.
I have a product rave, something I've never done on my blog, but after using this product I needed to share it! Recently I did a blog post about my Lush haul, which you can see here. I purchased the new bath bomb called Granny Takes a Dip, which you can purchase here for $6.95, and I highly suggest that you do! I need to make another trip to a Lush store. I tried this on Saturday night and I put the whole bath bomb into the bath tub (which I didn't need to, but I didn't know when I would be able to use it again, so I figured why not just use it all?).
It's just amazing. This bath bomb made my skin SO soft. I have really dry skin, especially in the winter, I am always applying lotion after I shower, but with this bath bomb, I didn't even bother using lotion. This kept my skin soft all night and the whole next day. Not to mention it smells like Fun Dip!
(I apologize for the dark photos. I didn't have good lighting in my bathroom).
Not only does it create a lot of bubbles but it changes your water all different fun colors!
Have you tried any of Lush's Bath Bomb's? Which ones are your favorites?
I definitely need some suggestions, I'd love to try more of them.


Nowadays, the free software movement and the diversity of open source tools encourage designers, artists and developers to question the nature of the tool they are using and its place in their creative process. They are invited to learn, modify and create their own tools. Creating tools forms an integral part in the work of a graphic designer. The tool shapes the work. Can we imagine new kind of publishing tools that change the way we present our works, create printed matter and more?
Sarah Garcin tries to answer this question, by creating the PJ Machine (Publishing Jockey Machine), a box with arcade buttons to control web interface for live publishing. The Machine allows to create layout design with text and images, and generate a pdf to print.
In the same way, the participants were invited to imagine and prototype new and open source publishing tool. The tools created there offered new kinds of interactions and revolutionized the publication process.


text:
"Shelter Me" is a song by American glam metal band Cinderella. It serves as the lead single from the band's third studio album, Heartbreak Station. It peaked at #36 on the Billboard Hot 100.

Music video
The music video features appearances by  Little Richard, Shelley Duvall, Pamela Anderson, Dweezil Zappa, and Harry Shearer.

The video was named on the New York Times list of the 15 Essential Hair-Metal Videos.

Charts

References

1990 songs
Cinderella (band) songs
Songs written by Tom Keifer
Mercury Records singles

redpajama_set_name: RedPajamaWikipedia


" For almost a year now, we have been working up a business case for the use of the Old Social Work Building. It has long been suggested that the building would make an ideal Gateway for the town centre. In calling for businesses to participate in the project we were contacted by a playgroup facility that was keen to expand their operation. We worked for many hours on an exciting plan; hammered out a funding package; produced detailed plans and got as far as obtaining builders quotes for the renovation of the premises." More on the NICE website.
Sadly NICE haven't delivered much at all have they?
totally agree with Anonymous at 8.16am, i'm all for organisations that do good for our town, but to perfectly honest NICE seem to be all talk and no action, what exactly have they achieved here for nairn so far ?