Get Rid of Skin Tags Home Remedies - Safely Skin Tags Removing Guides.
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If you want to get rid of various skin tag removal process will help!
In this day and age skin tags that are also known all over the globe as acrochordons actually bother so many men and women all around the world. As long as you want to find a proper home remedy for yourself then you ought to know that you may learn how to remove a skin tag with string, some say that it is the best way, in other words, sort of a safely remove. But you ought to remember that when you are getting proper drugs for skin tags removal you have to consult a doctor before over the counter drug will get to your system. There are various places on which you may have skin tags, before skin tag removal take a look at your sore armpits and see whether or not there are a lot of skin tags there. In case you see that the most problematic part of your body that is full of skin tags is your face then you ought to be extremely careful with skin tags removal. So many men and female actually require skin tag freeze but as long as you think that this kind of a process is not actually safe at all then you may purchase our castor oil for skin known as revitol. Our prices are actually incredibly fair and therefore with it, you will be able to remove color from skin after skin tags removal. Or in case you do not like the fact that one part of your body has a huge skin tag or a birthmark then with our products, you will forget about this kind of skin problems once and for all.
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In order for us to realize the whole process of skin tags removal and how to get rid of skin tags, we have to pay attention to the exact definition what skin tag is. Actually skin tag, to be frank, is a certain part of your skin, usually, it is relatively small and it is actually hanging from your body, but in very small amounts. All people have skin tags but this kind of skin issues actually can bring cancer in your life or any relative skin disease in general. There are various relative names for skin tags, but the most popular one actually is fibroma or papilloma. There are so many different thought and ideas about how to remove skin tags and the question on everyone's lips is what causes skin tags. By all means, there are various reasons for it that is why before you will decide that you actually want to undergo through a procedure of removing skin tags you have to read our article about how to get rid of skin tags. There are actually various products that you may utilize at home and at the same time such CVS drugs, from Walmart, Walgreens actually cost not very cheap at all. Actually, you may see that you have a skin tag and require removal on any part of your organism in general. Usually, this kinds of papillomas, in other words, skin tag are actually external. Right now we are going to tell you where this kind of skin tags usually can be found and how can you spot this kind of skin tags for removal in time.
A lot of men and women actually have skin tags on their eyelids, on this part of the body removing skin tags is actually very difficult but still it is possible as long as you will find a proper and most suitable way for removing skin tags and with us you will know how to remove skin tags fast and painlessly.
Women and men who are getting older seem to notice that their skin tags are actually getting bigger and more noticeable on their armpits. This kind of skin tags may actually lead to serious skin issues mainly because on your armpits you may manage to hurt and even cut off a skin tag with your shirt or another piece of clothes.
Every man will be aware of the fact what causes skin tags after reading it!
As far as you want to find out about various causes of skin tags and on what parts of your skin you will see skin tags in general then you ought to continue reading.
First of all, you ought to know that women actually have a lot of skin tags under their breasts, that is why it is actually essential for women to be careful while there are putting on their clothes and a bra in particular.
Be careful with a groin you may see that there is actually a very insecure zone full of skin tags.
Men are more likely to have a problematic skin full of skin tags removing which is going to be complicated on their upper chest part.
In case you have a lot of skin tags all over your neck then it is actually time for you to get skin tags oil or any kind of a product that you may find here on our online website pharmacy.
Choose the one that you prefer and after that, it will be better to talk to the doctor about certain kind of medication that you will use as a skin tag removal.
How to get rid of skin tags on dog – with Walmart it is simple for sure!
We have prepared so many interesting facts about skin tags and various kinds of papillomas for you, as long as you are interested in learning about skin tags then all you ought to do is to keep reading our article that was created just for you.
As you may or may not know already skin tags are actually certain types of benign tumors that are visible only on the surface of your body.
There are certain men and women who are actually more likely to have progressive cancer after skin tags than others.
In case you have a lot of skin folds all over your body then you will see that you have skin tags all over these parts of your body.
If you are one of those men who actually enjoy eating a lot and your lifestyle is actually very poor then you are more likely to have skin tags and complications after it.
As you have figured out already obesity is actually a very common trigger of the developing of skin tags on your body.
Usually, men and women decide that they want to get rid of skin tags just in order to have a better appearance.
In case you have skin tags all over your body and a lot so they are mainly on your face then you definitely have to get rid of skin tags on this part.
We all want to know what causes skin tags and right here you find out!
Sometimes you want to find out about various ways of getting rid of skin tags but you will find it extremely problematic to realize why they actually occur on the body. We want you to know that skin tags can be removed either by excision or on some other level you may actually utilize freezing or special oil for getting rid of skin tags and other kinds of appaloosas.
A lot of people actually assume that when you remove skin tags you will prologue others to appear.
As long as you realize that you need to get rid of skin tags then you will have to go to the doctor and tell him what actually is bugging you and whether or not skin tags actually are getting damaged by your movement or your clothing's.
If you will choose a proper cure and order from Walmart then you will manage to have a smooth skin and the risk of you having problems with cancer and other serious illnesses in this field will decrease.
By all means, the skin tags removal process is not simple but we will aid you!
In case your do not know a lot about skin tags then we want to inform you that those are small tumors that usually do not come with so many various symptoms. They are not simple birthmarks because usually, they are hanging a little bit but at the same time, they may cause problems with health in your life. For instance, in case you have been scratching a lot of skin tags and they were getting red and buffed, or you damaged one of the skin tags with a certain piece of jewelry then you have to think about how to remove a skin tag.
Usually skin tags they consist of certain fibers, by the way, it can be a fat cell or epidermis.
In case you have a lot of skin tags and you want to find out how to get rid of these kinds of papillomas then you ought to remember that a lot of people can actually inherit a lot of skin tags all over the body.
If you want to get rid of skin tag that is bugging you on the face or any other part of the body then all you have to do is to freeze it with our outstanding product.
For those of you who want to know how to improve the total health and never get under risk of having problems with cancer then removing skin tags is actually the best decision for you.
Be careful and never scratch your skin tags at all.
This way you may actually infect skin tags one way or the other.
Various products will help you to avoid skin tags at home!
There are a lot of people who have plenty of skin tags all over the body but at the same time, they fail to notice that these kinds of things are actually present until these appaloosas are scratched or bleeding. If you see that your papillomas can not go away on their own or you have hurt yourself with a razor or other thing then you ought to go to the wellqualified doctor.
A lot of people assume falsely that these kinds of skin tags may actually disappear on its own one day but mainly it is not happening at all. We advise you never to scratch your skin tags even when they are actually itchy because this way you are more likely to have infected papillomas in the future. You ought to realize that as soon as you will be able to go to the doctor and decide on the best way for you to get rid of skin tags then the chine of increasing lines or canсer in your life will drop noticeably. You should remember that no one else is going to take care of your total health apart from you that is why it is your entire responsibility. You have to spot every illness in time and in case you want to prevent various illnesses and diseases than you ought to get rid of skin tags right away. Do not hesitate and think that various illnesses are going to be avoided, you ought to take certain kinds foal precautions in order to be sure of it.
Right now you know that diabetes and obesity actually can cause a skin tag, and as longer as you are eating too much junk food and other kinds of food you are more likely than other to get problems in this area. Try to go on a diet, eat fewer cakes and products that consist of too much fat. As soon as you will be able to control your diet then you will feel healthy and with our aid, you will know what causes skin tags and how to remove skin tags in a heartbeat.


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text:
Q: Laradock: Install image magik I am trying to install image magik inside laradock
https://github.com/laradock/laradock
I have setup nginx , mysql, redis and elasticsearch.
I have tried installing the image magik inside php-fpm with
RUN apt-get -y update && \
    apt-get install pkg-config libmagickwand-dev -y && \
    pecl install imagick
RUN docker-php-ext-enable imagick
But still image are not generated.

A: I got it to working by adding following into the docker file of php-fpm for docker image of https://github.com/laradock/laradock
RUN apt-get update && apt-get install -y
git libmagick++-dev
--no-install-recommends &&
git clone https://github.com/mkoppanen/imagick.git &&
cd imagick && git checkout phpseven && phpize && ./configure &&
make && make install &&
docker-php-ext-enable imagick &&
cd ../ && rm -rf imagick

Also set PHP_FPM_INSTALL_EXIF=true in the .env next to docker-compose.yml
Remove the previous containers and images and create new build

A: In the .env file there is a variable for installing ImageMagick (In Laradock v7.x )
It's false by default but setting it to PHP_FPM_INSTALL_IMAGEMAGICK=true should do it.

A: Please try to rebuild the docker containers via the following command.
docker-compose build --no-cache

A: in .env file turn WORKSPACE_INSTALL_IMAGEMAGICK to true and
in workspace's Dockerfile add apt-get update &&\ on IMAGEMAGICK section like this:
    ###########################################################################
# ImageMagick:
###########################################################################

USER root

ARG INSTALL_IMAGEMAGICK=false
ARG IMAGEMAGICK_VERSION=latest
ENV IMAGEMAGICK_VERSION ${IMAGEMAGICK_VERSION}

RUN if [ ${INSTALL_IMAGEMAGICK} = true ]; then \
    apt-get update && \
    apt-get install -y libmagickwand-dev imagemagick && \
    if [ $(php -r "echo PHP_MAJOR_VERSION;") = "8" ]; then \
      apt-get install -y git && \
      cd /tmp && \
      if [ ${IMAGEMAGICK_VERSION} = "latest" ]; then \
        git clone https://github.com/Imagick/imagick; \
      else \
        git clone --branch ${IMAGEMAGICK_VERSION} https://github.com/Imagick/imagick; \
      fi && \
      cd imagick && \
      phpize && \
      ./configure && \
      make && \
      make install && \
      rm -r /tmp/imagick; \
    else \
      pecl install imagick; \
    fi && \
    echo "extension=imagick.so" >> /etc/php/${LARADOCK_PHP_VERSION}/mods-available/imagick.ini && \
    ln -s /etc/php/${LARADOCK_PHP_VERSION}/mods-available/imagick.ini /etc/php/${LARADOCK_PHP_VERSION}/cli/conf.d/20-imagick.ini && \
    php -m | grep -q 'imagick' \
;fi

redpajama_set_name: RedPajamaStackExchange


text:
we-ef VLR100 Series
Available from 7.5W-37.5W, the series includes five standard lengths, from 328mm to 1,528mm, with customised lengths available in 100mm increments on request. The luminaires can be tilted up to 180°, enabling the light direction to be adapted. A variable suspension technique allows post-installation, fine-tuning adjustments to be made on-site to ensure precision light distribution. The VLR100 series is available in [LB] wide; [LM] medium; [LE] narrow; [LEE] very narrow symmetric beam distributions and an asymmetric version [LA10]. The shorter version is fitted with a separate driver while longer versions have an integrated driver.
www.weef.de

redpajama_set_name: RedPajamaCommonCrawl


text:
Omics score: 25
Transcription profiling of mouse heart, brain, and skeletal muscle to determine the rffect of age, calorie restriction and resveratrol on gene expression
ABSTRACT: Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed mice from middle age (14-months) to old age (30-months) either a control diet, a low dose of resveratrol (4.9 mg kg-1 day-1), or a calorie restricted (CR) diet and examined genome-wide transcriptional profiles. We report a striking transcriptional overlap of CR and resveratrol in heart, skeletal muscle and brain. Both dietary interventions inhibit gene expression profiles associated with cardiac and skeletal muscle aging. Gene expression profiling suggests that both CR and resveratrol may retard some aspects of aging through alterations in chromatin structure and transcription. Resveratrol, at doses that can be readily achieved in humans, fulfills the definition of a dietary compound that mimics some aspects of CR. Experiment Overall Design: Heart, neocortex tissue, and gastrocnemius muscle was collected from young and old mice at 5 and 30 months of age, respectively; mice were subjected to either a calorie restricted diet or a control diet supplemented with resveratrol
ORGANISM(S): Mus musculus
SUBMITTER: Jamie Barger
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice.
Barger Jamie L JL Kayo Tsuyoshi T Vann James M JM Arias Edward B EB Wang Jelai J Hacker Timothy A TA Wang Ying Y Raederstorff Daniel D Morrow Jason D JD Leeuwenburgh Christiaan C Allison David B DB Saupe Kurt W KW Cartee Gregory D GD Weindruch Richard R Prolla Tomas A TA
PloS one 20080604 6
Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed mice from middle age (14-months) to old age (30-months) either a control diet, a low dose of resveratrol (4.9 mg kg(-1) day(-1)), or a calorie restricted (CR) diet and examined genome-wide transcriptional profiles. We report a striking transcriptional overlap of CR and resveratrol in heart, skeletal muscle and brain. Both dietary interven ...[more]
Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle
Project description:Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed mice from middle age (14-months) to old age (30-months) either a control diet, a low dose of resveratrol (4.9 mg kg-1 day-1), or a calorie restricted (CR) diet and examined genome-wide transcriptional profiles. We report a striking transcriptional overlap of CR and resveratrol in heart, skeletal muscle and brain. Both dietary interventions inhibit gene expression profiles associated with cardiac and skeletal muscle aging. Gene expression profiling suggests that both CR and resveratrol may retard some aspects of aging through alterations in chromatin structure and transcription. Resveratrol, at doses that can be readily achieved in humans, fulfills the definition of a dietary compound that mimics some aspects of CR. Keywords: aging intervention study Overall design: Heart, neocortex tissue, and gastrocnemius muscle was collected from young and old mice at 5 and 30 months of age, respectively; mice were subjected to either a calorie restricted diet or a control diet supplemented with resveratrol
Resveratrol prevents diet-induced arterial degeneration and stiffening in nonhuman primates
Project description:Cardiovascular (CV) disease is a leading cause of morbidity and mortality in Western societies. Even after accounting for traditional CV risk factors (e.g. obesity, smoking and hypertension), the inflammation-driven thickening and stiffening of central arteries is a strong predictor of adverse outcomes. Arterial wall changes are universally associated with advancing age and show unparalleled worsening in metabolic syndrome. In mice, resveratrol ameliorates a high-fat diet induced arterial wall inflammation and slows age-associated physiologic deteriorations within the arterial wall. Here we tested resveratrol in adult male rhesus monkeys, an experimental model relevant to humans. A diet rich in fat and sucrose (HFS) led to an increase in body weight as well as thickening and stiffening of the aortic wall, marked by diffuse inflammation, fibrosis and fat infiltration. Dietary resveratrol supplementation prevented diet-induced structural and functional alterations within the aortic wall, and abrogated the deleterious vascular endothelial and smooth muscle responses. Integrative genomic and proteomic analyses of aortic tissues revealed molecular signatures consistent with improved vascular functions. Thus, resveratrol conferred protection against the initiation of diet-induced inflammatory events that progress to pathological thickening and stiffening of large arteries. Dietary resveratrol may therefore hold promise as a novel therapy to ameliorate metabolic stress-induced CV disease. After baseline assessment, four male rhesus monkeys remained on the healthy standard diet (SD), 10 male rhesus monkeys were begun on a high fat/high sucrose (HFS) diet and 10 male rhesus monkeys were begun on a high fat/high sucrose (HFS) diet plus Resveratrol, 80mg/day. After one year of dietary intervention, the amount of resveratrol was increased to 240mg/day for one additional year. Tissues were then harvested for the array experiments.
Resveratrol Diet Aging (Heart, Liver, Muscle and Fat Tissue)
Project description:Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending lifespan A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related diseases in laboratory animals is greatly sought after. We and others have shown that resveratrol mimics effects of DR in lower organisms. In mice, we find that resveratrol induces gene expression patterns in multiple tissues that parallel those induced by DR and every-other-day feeding. Moreover, resveratrol-fed elderly mice shows a marked reduction in signs of aging including reduced albuminuria, decreased inflammation and apoptosis in the vascular endothelium, increased aortic elasticity, greater motor coordination, reduced cataract formation, and preserved bone mineral density. However, mice fed a standard diet did not live longer when treated with resveratrol beginning at mid-life. Our findings indicate that resveratrol treatment has a range of beneficial effects in mice but does not increase the longevity of ad libitum-fed animals when started mid-life. Male C57BL/6NIA mice at 11 months of age were maintained on a standard purified mouse diet (AIN-93G) for one month prior to the start of the experiment. Beginning at one year of age, SD and EOD groups were fed a standard AIN-93G diet or AIN-93G plus 0.01% or 0.04% resveratrol for the duration of the study. Three separate groups were placed on an HC diet (AIN-93G modified by the addition of hydrogenated coconut oil to provide 60% of calories from fat) or HC + 0.01% or 0.04% resveratrol 6 weeks later and remained on those diets throughout the study. SD and HC mice were fed ad libitum. EOD mice were fed ad libitum on alternate days then moved to a separate cage without food for 24 h. Food intake and body weight were measured on a weekly basis for the duration of the study.
A weekly alternating diet between caloric restriction and medium fat protects the liver from NAFLD in middle aged C57BL/6J mice
Project description:SCOPE: We investigated whether a novel dietary intervention consisting of an every-other-week calorie-restricted diet could prevent nonalcoholic fatty liver disease (NAFLD) development induced by a medium-fat (MF) diet. METHODS AND RESULTS: Nine-week-old male C57BL/6J mice received either a (i) control (C), (ii) 30E% calorie restricted (CR), (iii) MF (25E% fat), or (iv) intermittent (INT) diet, a diet alternating weekly between 40E% CR and an ad libitum MF diet until sacrifice at the age of 12 months. The metabolic, morphological, and molecular features of NAFLD were examined. The INT diet resulted in healthy metabolic and morphological features as displayed by the continuous CR diet: glucose tolerant, low hepatic triglyceride content, low plasma alanine aminotransferase. In contrast, the C- and MF-exposed mice with high body weight developed signs of NAFLD. However, the gene expression profiles of INT-exposed mice differed to those of CR-exposed mice and showed to be more similar with those of C- and MF-exposed mice with a comparable body weight. CONCLUSIONS: Our study reveals that the INT diet maintains metabolic health and reverses the adverse effects of the MF diet, thus effectively prevents the development of NAFLD in 12-month-old male C57BL/6J mice. Male C57Bl/6J mice were divided to 4 dietary intervention groups: Control (AIN-93W), 30% calorie restriction (CR; AIN-93W-CR), medium fat (MF; AIN-93W-MF; 25% energy from fat) and intermittent diet (INT; weekly alternating diet between AIN-93W-MF ad lib and 40% CR of AIN-93W). We performed various measurements on metabolic parameters and gene expression analysis on the liver. This entry represents the microarray data of the liver gene expression of each mouse.
Resveratrol supplementation does not improve metabolic function in non-obese women with normal glucose tolerance
Project description:Resveratrol has been reported to improve metabolic function in metabolically-abnormal rodents and humans, but has not been studied in non-obese people with normal glucose tolerance. We conducted a randomized, double-blind, placebo-controlled trial to evaluate the metabolic effects of 12 weeks of resveratrol supplementation (75 mg/day) in non-obese, postmenopausal women with normal glucose tolerance. Although resveratrol supplementation was well-tolerated and increased plasma resveratrol concentration without adverse effects, it did not change body composition, resting metabolic rate, plasma lipids, or inflammatory markers. A two-stage hyperinsulinemic-euglycemic clamp procedure, in conjunction with stable isotopically-labeled tracer infusions, demonstrated that resveratrol did not increase liver, skeletal muscle, or adipose tissue insulin sensitivity. Consistent with the absence of in vivo metabolic effects, resveratrol did not affect its putative molecular targets, including AMPK, Sirt1, Nampt, and Pgc-1α, in either skeletal muscle or adipose tissue. These findings demonstrate that resveratrol supplementation does not have metabolic effects in non-obese women. We compared gene expression profile in subcutaneous abdominal adipose tissue and skeletal muscle (vastus lateralis) biopsy samples obtained from non-obese people before and after 1) placebo (PLC), 2) resveratrol (RES), and 3) calorie restriction (CR) intervention.
Skeletal muscle PGC-1a mediates mitochondrial, but not metabolic, changes during calorie restriction.
Project description:Calorie restriction (CR) is a dietary intervention that extends lifespan and healthspan in a variety of organisms. CR improves mitochondrial energy production, fuel oxidation and reactive oxygen species scavenging in skeletal muscle and other tissues, and these processes are thought to be critical to the benefits of CR. PGC-1a is a transcriptional coactivator that regulates mitochondrial function and is induced by CR. Consequently, many of the mitochondrial and metabolic benefits of CR are attributed to increased PGC-1a activity. To test this model for the first time, we examined the metabolic and mitochondrial response to CR in mice lacking skeletal muscle PGC-1a (MKO). Surprisingly, MKO mice demonstrated a normal improvement in glucose homeostasis in response to CR, indicating that skeletal muscle PGC-1a is dispensable for the whole-body benefits of CR. In contrast, gene expression profiling and electron microscopy demonstrated that PGC-1a is required for the full CR-induced increases in mitochondrial gene expression and mitochondrial density in skeletal muscle. These results demonstrate that PGC-1a is a major regulator of the mitochondrial response to CR in skeletal muscle, but surprisingly show that neither PGC-1a nor mitochondrial biogenesis in skeletal muscle are required for the metabolic benefits of CR. Control (FLOX) and PGC-1a skeletal muscle specific knock out (MKO) mice were placed on a control diet [C] or a calorie restriction diet [CR] for 12 weeks. RNA was isolated from TA/EDL muscles for microarray analysis. The following numbers of mice were analyzed from each group: C FLOX: n = 6; C MKO: n = 7; CR FLOX: n = 6; CR MKO: n = 7. Mice were mixed C57/BL6 and 129 background.
Intermittent calorie restriction largely counteracts the adverse health effects of a moderate-fat diet in aging C57BL/6J mice
Project description:Calorie restriction (CR) has been shown to extend life- and health-span in model species. For most humans, a life-long CR diet is too arduous to adhere to. The aim of this study was to explore whether weekly intermittent CR can 1) provide long-term beneficial effects and 2) counteract diet-induced obesity in male aging mice. In this study, we have exposed C57Bl/6J mice for 24 months to an intermittent (INT) diet, alternating weekly between CR of a control diet and ad libitum moderate-fat (MF) feeding. This weekly intermittent CR significantly counteracted the adverse effects of the MF diet on mortality, body weight and liver health markers in male 24-month-old mice. Hepatic gene expression profiles of INT-exposed animals appeared much more comparable to CR than to MF-exposed mice. At 12 months of age, a subgroup of MF-exposed mice was transferred to the INT diet. Gene expression profiles in the liver of the 24-month-old diet switch mice were highly similar to the INT-exposed mice. However, a small subset of genes was consistently changed by the MF diet during the first phase of life. Weekly intermittent CR largely, but not completely, reversed adverse effects caused by a MF diet. Overall design: Male C57Bl/6J mice were divided to 3 dietary intervention groups: Control (AIN-93W), 30% calorie restriction (CR; AIN-93W-CR) and medium fat (MF; AIN-93W-MF; 25% energy from fat). Dietary interventions started at the age of 9 weeks and sacrifice was performed at the age of 6, 12, 24 and 28 months. We performed various measurements on metabolic parameters and gene expression analysis. This entry represents the microarray data. The array data from the 6-, 12- and 24-month-old mice exposed to the Control, CR and MF diet have been published before, and are also available under GEO accession number GSE84495.
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on a high-fat, high-sugar diet.
Project description:Obesity is associated with a chronic, low-grade, systemic inflammation that may contribute to the development of insulin resistance and type 2 diabetes. Resveratrol, a natural compound with anti-inflammatory properties, is shown to improve glucose tolerance and insulin sensitivity in obese mice and humans. Here we tested the effect of a 2-year resveratrol administration on the pro-inflammatory profile and insulin resistance caused by a high-fat, high-sugar (HFS) diet in white adipose tissue (WAT) from rhesus monkeys. Eighty mg/day of resveratrol for 12-month followed by 480 mg/day for the second year decreased adipocyte size, increased sirtuin 1 expression, decreased NF-kB activation and improved insulin sensitivity in visceral but not subcutaneous WAT from HFS-fed animals. These effects were reproduced in 3T3-L1 adipocytes cultured in media supplemented with serum from monkeys fed HFS +/- resveratrol diets. In conclusion, chronic administration of resveratrol exerts beneficial metabolic and inflammatory adaptations in visceral WAT from diet-induced obese monkeys. Twenty-four adult (7-13 years old) male rhesus monkeys (Macaca mulatta) were housed individually in standard nonhuman primate caging on a 12h light/12h dark cycle, room temperature (78 +/- 2 degrees F), and humidity at 60 +/- 20%. One pairing was maintained throughout the study; all other monkeys had extensive visual, auditory, and olfactory but limited tactile contact with monkeys housed in the same room. Monkeys received 2 meals per day at estimated ad libitum levels throughout the study. Water was always available ad libitum. Monkeys were monitored minimally 3 times daily by trained animal care staff. During baseline assessments, all monkeys were maintained on a commercially available closed formula monkey chow. After baseline assessment, four male rhesus monkeys remained on the healthy standard diet (SD), 10 male rhesus monkeys were begun on a high fat/high sucrose (HFS) diet and 10 male rhesus monkeys were begun on a high fat/high sucrose (HFS) diet plus Resveratrol, 80mg/day. After one year of dietary intervention, the amount of resveratrol was increased to 480mg/day for one additional year. Tissues were then harvested for the array experiments.
Omega-3 fatty acids partially revert the metabolic gene expression profile induced by long-term calorie restriction
Project description:Calorie restriction (CR) consistently extends longevity and delays age-related diseases across several animal models. We have previously shown that different dietary fat sources can modulate life span and mitochondrial ultrastructure, function and membrane fatty acid composition in mice maintained on a 40% CR. In particular, animals consuming lard as the main fat source (CR-Lard) lived longer than CR mice consuming diets with soybean oil (CR-Soy) or fish oil (CR-Fish) as the predominant lipid source. In the present work, a transcriptomic analysis in liver and skeletal muscle was performed in order to elucidate possible mechanisms underlying the changes in energy metabolism and longevity induced by dietary fat in CR mice. After 8 months of CR, transcription downstream of several mediators of inflammation was inhibited in liver. In contrast, proinflammatory signaling was increased in the CR-Fish versus other CR groups. Dietary fish oil induced a gene expression pattern consistent with increased transcriptional regulation by several cytokines (TNF, GM-CSF, TGF-b) and sex hormones when compared to the other CR groups. The CR-Fish also had lower expression of genes involved in fatty acid biosynthesis and increased expression of mitochondrial and peroxisomal fatty acid b-oxidation genes than the other CR diet groups. Our data suggest that a diet high in n-3 PUFA, partially reverts CR-related changes in gene expression of key processes, such as inflammation and steroid hormone signaling, and this may mitigate life span extension with CR in mice consuming diets high in fish oil. Sixteen male C57BL/6 mice were purchased at 14 weeks of age from the Jackson Laboratory (Sacramento, CA) and fed a commercial rodent chow diet (Harlan Teklad #7012). The mice were allowed ad libitum access to food and their food intake was monitored for two weeks. At 4 months of age, the animals were randomly assigned to four groups. The Control group received 95% of the daily ad libitum caloric intake (13.6 kcal/day) to avoid excessive weight gain and obesity, and the other three groups received 60% of the ad libitum consumption (8.6 kcal/day). A total of 31 mice samples (eight control, eight fish, eight lard and seven soy distributed in liver (n=16) and muscle (n=15) tissues) were analyzed by RNA-Sequencing. However, 2 samples (1071 control liver [JFM42H], 1125 fish muscle [JFM45D]) were discarded for further analysis after performing cluster analysis (they were clustering in a different groups). Also their RIN values were not as high as those of the other samples, indicating lower quality of the RNA.
Comparative transcriptomic profiling of peripheral blood mononuclear cells (PBMNCs) isolated from pigs exposed to an atherogenic diet (AD) or to an AD supplemented with Grape Extract (GE) and/or Resveratrol (RES).
Project description:We used Affymetrix microarrays to investigate gene expression changes in PBMNCs isolated from female and male pigs to determine significant modulatory effects that may have been induced by the intake of GE and (or) RES during 4 months in animals fed an atherogenic diet (AD) . The aim of this work was to determine whether the intake of low doses of a Grape Extract (GE; 1 g/70 Kg animal body weight) and (or) Resveratrol (RES; 18 mg/70 Kg animal body weight) exerted any modulatory effects, at the level of gene expression, in PBMNCs isolated from female and male pigs exposed to an atherogenic diet (AD) for 4 months. We isolated PBMNCs, and the corresponding total RNA, from 2 female and 2 male pigs for each group. Pure RNA was extracted from the PBMNCs for microarrays analyses (Affymetrix) and gene differential expression determined between the AD fed animals and control (CT) animals (to determine the effects of a high-fat consumption) and between the AD fed animals supplemented with GE and (or) RES and the animals fed the AD diet alone (to determine the effects of GE and (or) RES on the fat consumption). In addition, the effects of the consumption of GE and RES against a standard control diet (CT) were also determined. Differential gene expression: 1) AD vs CT (response to exposure to a high-fat diet); 2) AD-GE vs AD (modulatory effects of the intake of a grape extract on high-fat fed animals); 3) AD-GE-RES vs AD (modulatory effects of the intake of a resveratrol-enriched grape extract on high-fat fed animals); 4) AD-RES vs AD (modulatory effects of the intake of resveratrol on high-fat fed animals); 5) CT-GE-RES vs CT (modulatory effects of the intake of a resveratrol-enriched grape extract on animals fes a standard pig chow).


All first round contributors to my indiegogo campaign will get their thank you gifts sent in the mail today!
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Candy Boyd, left, owner of Boyd Funeral Home, is helped as she brings in the body of Lydia Nunez, who died from COVID-19, during a funeral service at the Metropolitan Baptist Church, July 21, in Los Angeles. When people began dying from the coronavirus in the United States, for a few weeks funeral home owner Boyd declined to receive the remains of such patients. (AP Photo/Marcio Jose Sanchez)
MacArthur asserts 'there is no pandemic'
NewsMark Wingfield | September 3, 2020
The Los Angeles megachurch pastor who has been at war with the city, county and state over COVID-19 health and meeting restrictions told his congregation last Sunday the truth has finally come out: "There is no pandemic."
The congregation of Grace Community Church erupted in applause with these words from their pastor, who has international standing among conservative evangelicals and Calvinists as an author, teacher, preacher and radio show host.
John MacArthur preaches at Grace Community Church on Sunday, Aug. 16, in defiance of a court order on public health.
"I don't want to offer myself as any kind of an expert, but a rather telling report came out this week, and, for the first time, we heard the truth," he said in his Aug. 30 sermon. "The CDC … said that, in truth, 6% of the deaths that have occurred can be directly attributable to COVID. 94% cannot. Of the 160,000 people that have died, 9,210 actually died from COVID. There is no pandemic."
MacArthur's carefree message about a global pandemic runs counter to all reputable scientific reporting on the subject and misrepresents the CDC data.
"What is embarrassing for MacArthur is that this has been known for months. The CDC has released reports before showing the underlying health conditions of deaths and hospitalized patients," wrote Warren Throckmorton, professor of psychology at Grove City College in Pennsylvania, who has been tracking MacArthur and other church responses to the virus online. "Yet, in ominous tones, MacArthur makes it appear he is revealing some previously concealed truth. While his scary announcement may serve his persecution narrative, it also makes his congregation and followers more vulnerable to the virus."
For his part, MacArthur said he doesn't know anyone who has been ill with the virus.
"We've all been suspicious of the fact that we've been meeting together now for weeks and weeks and weeks, and we don't know anyone who's ill," the pastor said. "Nobody in our congregation has ever been to the hospital with this."
"We know there are reasons for this that have nothing to do with the virus. There's another virus loose in the world, and it's the virus of deception."
Then MacArthur spun his non-expert opinion on epidemiology to make a point about spiritual warfare: "We know there are reasons for this that have nothing to do with the virus. There's another virus loose in the world, and it's the virus of deception, and the one who is behind the virus of deception is the arch-deceiver, Satan himself. And it's not a surprise to me that, in the midst of all this deception, the great effort that is going on is to shut down churches that preach the gospel."
Within hours of the sermon being posted online, commentators began rebutting MacArthur's grasp of the CDC data and questioning where he was getting his interpretation. Links were cited to the conspiracy theory network known as QAnon. And others pointed a finger at MacArthur's attorney in his fight with county officials, Jenna Ellis, who also represents President Donald Trump as a lawyer. Earlier Trump had tweeted similarly misleading information about the CDC data but that tweet was later removed.
Experts and watchdogs took quick aim at MacArthur's statements and labeled them dangerous.
The so-called co-morbidity rate refers to people who were killed by coronavirus but also had some other underlying health condition, whether heart disease or diabetes or asthma. Experts say those people still were killed by coronavirus, not by their underlying condition. In other words, they would not have died at this time from those earlier diagnoses, but did in fact die from coronavirus.
MacArthur's attention-getting declaration came just days before he and the church face off with Los Angeles County public health officials in one of the most-watched legal actions related to public health mandates against churches meeting for in-person worship.
Also, on Wednesday, Sept. 2, Grace Church announced that the City of Los Angeles was cancelling a 45-year-old lease agreement that allows the church to use city-owned property for parking and egress and ingress.
Ellis, the church's attorney, cited this as another example of government persecution of the church: "The only reason the county is attempting eviction is because John MacArthur stood up to their unconstitutional power grab. This is harassment, abusive and unconscionable."
It is hard to overstate MacArthur's influence in the most conservative wings of American evangelicalism.
Pastor D.J. Jenkins of Anthology Church in Studio City, Calif., wrote a post explaining this and accusing MacArthur of bearing false witness.
"I am only 39, have been in ministry only 17 years, and have a church of 35 people. No one cares much what I think," Jenkins wrote. "But John MacArthur has been in ministry for more than half a century, has helped create his own college and seminary, and has an influence parachurch ministry. When he says that the government response to COVID is part of a Satanically influenced 'virus of deception' to stop churches from gathering, Christians will believe him. Well-meaning people in my own congregation have brought up similar conspiracy-related theories."
The younger pastor concluded: "Christians in a pandemic need to be graciously shepherded to faithfulness through the hardship, not encouraged with false narratives which, if acted upon, could ultimately lead to the spread of the virus and increase deaths in their own communities."
MacArthur says Trump called to support his defiance of COVID-19 orders
Standoff continues between MacArthur and Los Angeles County
MacArthur defies late-night court order against indoor worship
How John MacArthur loves the Bible but not his neighbor
John MacArthur retains Trump lawyer in fight over COVID restrictions
MacArthur sues LA County, county countersues in fight over COVID restrictions
Tags:Mark WingfieldJohn MacArthurCOVID-19
Mark Wingfield


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"The strategy was not to lose" - Eteri Kublashvili interviews Ian Nepomniachtchi
by Eteri Kublashvili
5/6/2021 – Ian Nepomniachtchi won the Candidates Tournament 2020/2021, and in November he will play against Magnus Carlsen for the world title. In an extensive interview with Eteri Kublashvili after the Candidates, Nepomniachtchi talked about his preparations for the second part of the Candidates and revealed why he once was so frustrated during his preparations that he threw his "iPhone into the wall". He also talked about his key to success, Magnus Carlsen - "a very nice dude" - and why "there is never enough time to prepare". | Photo: Lennart Ootes
The Big Database 2022 contains more than 9.2 million games from 1560 to 2021 in the highest ChessBase quality standard with ChessBase opening classification with more than 100,000 key positions, direct access to players, tournaments, middlegame themes, en
Ian, you won one of the most important events in every chess player's career and qualified for the World Championship Match. It's a great achievement, congratulations! So, how do you feel now?
Thank you. I feel really exhausted because it was an incredible tournament in many, many senses of the word. First of all, I guess it took 400 days from start to finish, it is kind of outstanding. Well, when you read about chess history, players were travelling by sea, from America to Europe and so on… In our times, you know, it's not romantic at all because of the global pandemic thing.
I think the most difficult part was not playing chess, but these 13 months between the first and second legs, during which one somehow needed to keep one's focus, needed to prepare constantly thinking about other guys: what were they doing, how did they prepare, what were they going to play, because basically, it's one year between the tournaments and only seven games to prepare for. So, you should be ready that you're going to face completely different players in a completely different situation.
Yes, it was a very long and nervous period of expectation and negotiations, but still, in one of his interviews, Anatoly Karpov said that this one-year break would do you good because probably you would save more energy for the second part. Do you agree with this?
Well, especially now when I know the result – yes. Indeed, I'm not the person who should whine about this long break, since in the end, I won the whole thing. However, I'd say that this also would help other guys, because, you know, the Candidates Tournament is a very difficult competition, the stakes are very high, and there's only one place, so it doesn't matter if you finish on +1, or +2, or earn some rating: you should score the maximum amount of points, you should take the first place. Basically, you can earn some rating, you can play some good games, but all this will never make you happy unless you win the Candidates.
Complete interview at the website of the FIDE...
Eteri Kublashvili Eteri Kublashvili is a chessplayer and reports and photographs from all official tournaments for the Russian Chess Federation.


8 years agoFix admin, carousel and edit page. Upgrade modules.
Fix admin, carousel and edit page. Upgrade modules.
9 years ago The news block is now OK. Begin the implementation of the article templating.
The news block is now OK. Begin the implementation of the article templating.


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Posts Tagged 'August 4th'
Deep Purple – 08-04-15 – Freedom Hill Amphitheatre, Sterling Heights, MI
Deep Purple performs on August 4th, 2015 at Freedom Hill Amphitheatre in Sterling Heights, Michigan – photos by Chris Schwegler
Aug 05, 2015 | 1 Comment »
Keith Urban – 08-04-13 – Light the Fuse Tour 2013, DTE Energy Music Theatre, Clarkston, MI
Keith Urban performs on August 4th, 2013 during "Light the Fuse Tour 2013" at DTE Energy Music Theatre in Clarkston, Michigan – photos by Chris Schwegler
Little Big Town – 08-04-13 – Light the Fuse Tour 2013, DTE Energy Music Theatre, Clarkston, MI
Little Big Town performs on August 4th, 2013 during "Light the Fuse Tour 2013" at DTE Energy Music Theatre in Clarkston, Michigan – photos by Chris Schwegler
Dustin Lynch – 08-04-13 – Light the Fuse Tour 2013, DTE Energy Music Theatre, Clarkston, MI
Dustin Lynch performs on August 4th, 2013 during "Light the Fuse Tour 2013" at DTE Energy Music Theatre in Clarkston, Michigan – photos by Chris Schwegler
Five Finger Death Punch – 08-04-12 – Trespass America Tour, Meadow Brook Music Festival, Rochester Hills, MI
Five Finger Death Punch perform on August 4th, 2012 during the Trespass America Tour at Meadow Brook Music Festival in Rochester Hills, Michigan – photos by Chris Schwegler
Killswitch Engage – 08-04-12 – Trespass America Tour, Meadow Brook Music Festival, Rochester Hills, MI
Killswitch Engage perform on August 4th, 2012 during the Trespass America Tour at Meadow Brook Music Festival in Rochester Hills, Michigan – photos by Chris Schwegler
Trivium – 08-04-12 – Trespass America Tour, Meadow Brook Music Festival, Rochester Hills, MI
Trivium perform on August 4th, 2012 during the Trespass America Tour at Meadow Brook Music Festival in Rochester Hills, Michigan – photos by Chris Schwegler
Emmure – 08-04-12 – Trespass America Tour, Meadow Brook Music Festival, Rochester Hills, MI
Emmure perform on August 4th, 2012 during the Trespass America Tour at Meadow Brook Music Festival in Rochester Hills, Michigan – photos by Chris Schwegler
Jack Bruce – 08-04-10 – Hippiefest, DTE Energy Music Theatre, Clarkston, MI
August 4th, 2010 – Jack Bruce of Cream performs live on Hippiefest at DTE Energy Music Theatre in Clarkston, Michigan. Credit: Chris Schwegler.
Rare Earth – 08-04-10 – Hippiefest, DTE Energy Music Theatre, Clarkston, MI
August 4th, 2010 – Rare Earth performs live on Hippiefest at DTE Energy Music Theatre in Clarkston, Michigan. Credit: Chris Schwegler.
Mitch Ryder – 08-04-10 – Hippiefest, DTE Energy Music Theatre, Clarkston, MI
August 4th, 2010 – Mitch Ryder performs live on Hippiefest at DTE Energy Music Theatre in Clarkston, Michigan. Credit: Chris Schwegler.


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McMurray Musings
BY THERESA WELLS — Email
Not Your Usual Suspect… Ashley Laurenson
When she arrived in 2008 from New Zealand it was because her father, who had been offered an exciting employment opportunity, asked her if she wanted to go on an adventure in Canada. The then 18-year-old Ashley Laurenson packed her bags and came to Fort McMurray, a decision she regretted for the first three months, often wishing to go home. Yet in 2014, when her parents left Fort McMurray to relocate to another community in Alberta, Laurenson made the decision to stay in Fort McMurray. She says it is because while her immediate "real" family is very close and tight knit her other family, one formed of friends and colleagues, is now found in Fort McMurray.
"When I first got here I did nothing for a long time," says the perky Laurenson, her native accent still distinct despite her many years in Canada. It was only when she began working and meeting people that she began to develop a support network, a network in which a social media application called Twitter played a crucial role. It was through Twitter that she began to connect with people like Toddske and Tito of YMM Podcast and it was these connections that began to foster her strong relationship to the community of Fort McMurray and the development of a family of friends.
Having worked at a local clothing retailer, selling condos, managing a jewelry store and working for an oil sands company, Laurenson forged strong bonds with her new friends, including appearing on YMM Podcast and then venturing into the world of filmmaking with an acclaimed film short called "Arkham Rising". When the film short began to attract local, national and even international attention, Laurenson and her fellow filmmakers began to find themselves the focus of significant requests from other local filmmakers who were seeking assistance with their own film projects. The need they expressed led to the formation of the Fort McMurray Filmmakers Association, an organization dedicated to the promotion of film making in the region and providing assistance to aspiring filmmakers.
Since her early days in Fort McMurray of "doing nothing", Laurenson has progressed to being a key community member, noted not only for her social media presence and contribution to local filmmaking but her participation in a variety of non-profit causes and organizations. Laurenson says it all started when she simply made the choice to get involved.
"Without the community here I would not stay," says Laurenson, flashing a gleaming smile. "We have an awesome school system, we have great places like MacDonald Island Park, and it's a good place to raise a family – but you have to get off the sofa and do something," she adds.
Laurenson's successful transition from New Zealand to her new home in Canada is definitely the narrative of someone who may have started as "not your usual suspect", but who over time has contributed to the community in a ways that have made her not only a known figure, but a much respected member of the up and coming demographic of young community leaders.
Previous Article McMurray Musings
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THERESA WELLS
A freelance writer, blogger and professional communicator who is passionate about her child, her work, her pets, her community and the power of words, Theresa Wells believes perfection in life is achieved when she is surrounded by amazing people, fantastic stories, cold gin and really hot shoes.
Website: www.mcmurraymusings.com/
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Union County, South Dakota
Purpose & Mission
DWI Information
Juvenile Court/Process
Chamber Page – Check Policy
Information to a Victim of Crime
Victim's Letter to the Penitentiary
Community Health Nurse
Director of Equalization
Pandemic Information
Extension Office & Union County Fair
Courthouse Buildings & Ground
Weed & Pest
Commission Minutes
Commission Agendas
2010 – Press Releases
11/15/2010 Trent Himmingsen, a 37 year old rural Elk Point man, was sentenced on November 8, 2010 to fifteen years on one count of sexual contact with a child under sixteen and sentenced to seventy years with forty suspended on one count of first degree rape.
11/15/2010 Gary Wilson, a 50 year old Sioux Sioux City Nebraska man, was sentenced on Novemeber 8, 2010 to five years of supervised probation and a $1000 fine on one count of possession of a controlled substance charge.
10/29/2010 Michael Little, a 21 year old Sioux City Iowa man, was sentenced to five years with one year suspended for having violated his supervised probation on the original charge of escape.
10/29/2010 Jolene White, a 43 year old Dakota Dunes woman, was sentenced to 2 suspended years to the state penitentiary and 60 days in the county jail with a $1000 fine on the charge of 3rd offense driving under the influence.
10/29/2010 San Jose & Eric Castillo-Tello, two brothers both from Texas, both plead guilty to one count each of Grand Theft.
10/25/2010 Dustin Oberg, a 19 year old Beresford man, was sentenced to 15 years with 11 years suspended on one count of first degree burglary and one count of sexual contact.
10/25/2010 Chris Fodness, a 19 year old Beresford man, plead guilty to one count of third degree burglary of Fiesta Foods in Beresford SD.
10/06/2010 Renee Krumvieda, a 27 year North Sioux City SD womain, was sentenced to three 20 year sentences, all to run concurrent to each other on two counts of second dgeree burglary and one count of possession of controlled substances. All charges were enhanced to the Defendant being charged with a habitual offender information.
10/06/2010 Mikeal Moffatt, a 19 year old Hawarden IA man, plead guilty on August 16, 2010 to one count of second degree burglary.
10/06/2010 Gary Wilson, a 50 year old South Sioux City man, plead guilty on October 4, 2010 to one count of possession of controlled substance. Sentencing is set fo November 8, 2010, at 10:00 a.m.
10/01/2010 Alexis Tracy is hired as new county deputy state's attorney to replace Jeff Rarick who resigned his possition with the county to take a teaching position with ROTC at the University of South Dakota.
9/27/2010 Justin Emmick, a 33 year old Sioux City Iowa man, plead guilty and was sentenced to a suspended 60 day sentence and a fine of $2000 plus costs to one count of engaging in business without obtaining a sales tax license.
9/27/2010 Larry Gotch, a 35 year old McCook Lake man, was sentenced to 8 years concurrent with his Iowa felony charges on one count of receiving stolen property.
9/27/2010 Chad Gotch, a 34 year old McCook Lake man, was sentenced to 8 years concurrent with his felony Iowa charges on one count of receiving stolen property.
9/27/2010 Amandi Cota, a 25 year old Sioux City Iowa female, received a 7 year sentence with 4 years suspended after admitting to a probation violation on an origial charge of possession of controlled substances.
9/27/2010 Gerald Clay, a 20 year old Sioux City Iowa man, was re-sentence to a suspened 5 year sentence with 3 years of supervised probation after admitting to violating his probation on the origial charge of first degree escape.
9/27/2010 Vanessa Perez, a 27 year old Sioux City Iowa woman, was re-sentenced to a suspended 7 year sentence with 4 years of supervised probation after admitting to a violation of her probation on the original charge of possession of controlled substances.
9/27/2010 Autumn James, a 24 year old South Sioux City NE woman, was re-sentenced to a suspended 5 year sentence with supervised probation for 2 years after admitting to violating her probation on the original charge of possession of controlled substances.
9/01/2010 Dustin Oberg, a 19 year old Alcester SD man, plead guilty to one count of first degree burglary on August 30, 2010. Sentencing is set for October 25, 2010, at 10:30 a.m.
8/24/2010 Bill O'Quinn, a 39 year old Dixon NE man, was sentenced to a 4 year sentence with 2 years suspended on one count of possession of controlled substance.
8/24/2010 Alfred Cosentino, a 31 year old Omaha NE man, was sentenced to 7 years with 4 year suspended on one count of possession of controlled substances. Cosentino was also fined $500 on the charge of driving under the influence.
8/24/2010 Michael Brzostowski, a 47 year old Jefferson SD man, was sentenced to 180 days with work release in county jail and fined $1500 and placed on probation for 5 years for the charge of 4th offense driving under the influence charge.
8/24/2010 Melanie Newman, a 22 Yakima WA woman, was sentenced to 7 years with 4 years suspended on the charge of possession of controlled substances.
8/23/2010 Jason Schafer, a 39 year old Elk Point SD man, was sentenced to 100 days in county jail on the charge of misprision of a felony.
8/23/2010 Mikeal Moffatt, a 19 year old Hawarden IA man, plead guilty on August 16, 2010 to one count of second degree burglary.
8/20/2010 Alan Skogan, a 49 year old rural Elk Point man, was fined $350 on each of the two counts of inhumane treatment of an Animal.
8/20/2010 Lance Dunlap, a 25 year old Sioux City IA man, was sentenced to a suspended 2 year sentence and placed on supervised probation for one year and fined $750 on one count of Making False or Fraudulent Tax Returns. Dunlap was fined $300 on the misdemeanor charge of tattooing a minor.
7/26/2010 Thomas Varvais, a 19 year old Sioux City IA man, was sentenced to 40 years with 25 years suspended on the charge of second degree rape.
7/23/2010 Donald Voorhees, a 36 year old Sioux Falls SD man, was sentence to 5 years with 30 months suspended following a probation violation hearing wherein Voorhees was found to have violated his probation on the original charge of Possession of Marijuana (one to ten pounds).
7/22/2010 James Streuli, a 42 year old Jefferson SD man, was sentenced to 2 years with 6 months suspended and fined $750 on the charge of 3rd offense driving under the influence.
7/22/2010 Penny Birkley, a 41 year old Sioux City IA woman, was sentence to a suspended 10 year sentence with 10 year of supervised probation and fined $1000 and a restitution order for $24,902.81 on the charge of grand theft by embezzlement.
7/22/2010 Daniel Mincks, a 32 year old Vermillion SD man, was sentenced to a suspended 10 year sentence and supervised probation for 10 years with 90 days to the county jail on the charge of possession of controlled substance. Mincks was also fined $400 on a DWI charge.
7/22/2010 Kalen Hahn, a 29 year old Harrisburg SD man, was sentence to a 5 year sentence with 30 months suspended and fines and other cost totaling $1675.64 on the charge of 4th offense driving under the influence.
7/22/2010 Marie Meinen, a 31 year old Sioux City IA woman, received a suspended 10 year sentence with 7 years of supervised probation, a fine of $2000, and a sentence of 90 days in the county jail on the charge of grand theft by embezzlement.
7/22/2010 LeRoy Hawk II, a 22 year old Tulsa OK man, was sentenced to 180 days with 90 suspended in the county jail and a fine of $750 on the charge of possession of controlled substances.
7/22/2010 Sasha Eickholt, a 22 year old Sioux City woman, was sentenced to 5 years with 3 years suspended and a $500 fine for the charge of forgery.
7/22/2010 Temporarily Disabled Link
5/24/2010 Union County State's Attorney Office participates in Tobacco Inspections again this year.
5/24/2010 Christopher Jones, a 38 year old Sioux City IA man, was sentence to a 15 year sentences on each count of 3rd degree rape following his trial earlier this year.
5/24/2010 Thomas Varvais, an 18 year old Sioux City man, plead guity today to one count of second degree rape. Varvais remains in custody with his sentencing set for July 12, 2010 at 10:30 a.m.
5/21/2010 Alan Skogan, a 49 year old rural Elk Point man, was arrested on May 18, 2010 on eleven counts of Inhumane Treatment of an Animal. Each count is a class one misdemeanor.
5/17/2010 Matthew White, a 42 year old Beresford SD man, was sentenced to 15 years with 8 suspended on one count of possession of a controlled substance. White was sentenced to a consecutive sentence of 5 years for indecent exposure involving a child. White's sentence was enhanced due to his status as a habitutal offender.


Medidata Solutions Inc (NASDAQ:MDSO) shot up 7.5% during mid-day trading on Monday . The company traded as high as $81.22 and last traded at $80.55. 1,423,932 shares were traded during mid-day trading, an increase of 190% from the average session volume of 491,810 shares. The stock had previously closed at $74.93.
A number of brokerages recently issued reports on MDSO. William Blair began coverage on Medidata Solutions in a research report on Monday. They issued an "outperform" rating and a $74.93 price objective on the stock. BidaskClub downgraded Medidata Solutions from a "buy" rating to a "hold" rating in a research report on Monday, January 7th. Zacks Investment Research downgraded Medidata Solutions from a "buy" rating to a "hold" rating in a research report on Monday, January 28th. Leerink Swann began coverage on Medidata Solutions in a research report on Wednesday, January 2nd. They issued a "market perform" rating and a $70.00 price objective on the stock. Finally, TheStreet downgraded Medidata Solutions from a "b" rating to a "c+" rating in a research report on Thursday, December 20th. One analyst has rated the stock with a sell rating, five have assigned a hold rating, seven have issued a buy rating and one has assigned a strong buy rating to the company. The company presently has an average rating of "Buy" and a consensus price target of $82.91.
The company has a quick ratio of 2.71, a current ratio of 2.71 and a debt-to-equity ratio of 0.14. The stock has a market cap of $4.81 billion, a price-to-earnings ratio of 83.91, a PEG ratio of 5.12 and a beta of 1.35.
Medidata Solutions (NASDAQ:MDSO) last released its quarterly earnings results on Tuesday, February 12th. The company reported $0.45 earnings per share for the quarter, beating the Zacks' consensus estimate of $0.37 by $0.08. Medidata Solutions had a return on equity of 10.03% and a net margin of 8.17%. The business had revenue of $167.19 million for the quarter, compared to the consensus estimate of $168.08 million. During the same quarter last year, the business posted $0.41 earnings per share. The company's revenue for the quarter was up 18.1% on a year-over-year basis. Analysts forecast that Medidata Solutions Inc will post 0.8 earnings per share for the current fiscal year.
In other Medidata Solutions news, EVP Daniel Patrick Shannon sold 19,725 shares of the firm's stock in a transaction dated Tuesday, March 12th. The stock was sold at an average price of $75.17, for a total transaction of $1,482,728.25. Following the sale, the executive vice president now owns 70,497 shares in the company, valued at $5,299,259.49. The transaction was disclosed in a document filed with the Securities & Exchange Commission, which is available at the SEC website. Also, CFO Rouven Bergmann sold 12,512 shares of the firm's stock in a transaction dated Wednesday, February 6th. The shares were sold at an average price of $75.00, for a total value of $938,400.00. The disclosure for this sale can be found here. Insiders have sold 47,237 shares of company stock worth $3,568,628 in the last 90 days. Company insiders own 4.70% of the company's stock.
A number of hedge funds and other institutional investors have recently added to or reduced their stakes in the business. Benjamin F. Edwards & Company Inc. increased its holdings in shares of Medidata Solutions by 127.2% in the fourth quarter. Benjamin F. Edwards & Company Inc. now owns 945 shares of the company's stock worth $64,000 after buying an additional 529 shares during the period. Bronfman E.L. Rothschild L.P. increased its holdings in shares of Medidata Solutions by 26.9% in the fourth quarter. Bronfman E.L. Rothschild L.P. now owns 1,286 shares of the company's stock worth $87,000 after buying an additional 273 shares during the period. Oppenheimer Asset Management Inc. purchased a new position in shares of Medidata Solutions in the fourth quarter worth about $90,000. Canton Hathaway LLC purchased a new position in shares of Medidata Solutions in the first quarter worth about $109,000. Finally, Whittier Trust Co. of Nevada Inc. increased its holdings in shares of Medidata Solutions by 1,068.0% in the fourth quarter. Whittier Trust Co. of Nevada Inc. now owns 2,558 shares of the company's stock worth $172,000 after buying an additional 2,339 shares during the period.
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text:
Blackberry Jam is Jammin' on Song Writing
Adrian & Julian "Blackberry Jam"
School could not end fast enough for Adrian and Julian, 16 year old identical twin singing duo who prefer to spend their time making music.
After Rivenmaster announced a chance to win a scholarship to the 2013 Prodigy Camp Project, a summer program that brings together 20 of the most promising teenage songwriters and filmmakers to hone their craft, they actually got a call from the camp encouraging us to apply. Julian said,
"The chance to collaborate with other artists from around the world was really exciting to us."
Blackberry Jam has come a long way since third grade where they got their start entertaining their classmates with comedic singing routines at "Lunchbox Special". This past year, as high school sophomores they took a songwriting class and spent 90 minutes each day writing music and lyrics. For 6 weeks the twins work through the creative process, trying out different lyrics and riffs on their new song Seven Seas. Adrian said,
"Songwriting is hard! The music part is easy, but the lyrics just don't sound right."
A breakthrough came when their teacher suggested they collaborate with Desiree Hazleton, a classmate who was particularly skilled at writing lyrics.
"In the first session we had an entire verse and chorus written. Desiree would just crank out the lyric and it was so easy to put the music and vocals behind her words."
Within a few sessions they had an entire song, and ideas for 4 more projects. Collaboration was the key to success. By the end of the semester, their latest song, "End of the Night", was finished.
"End of the Night" Original By Blackberry Jam
Continue reading "Blackberry Jam is Jammin' on Song Writing"
Author RivenmasterPosted on 30-08-2013 28-03-2014 Categories Adrian Chirtea, Blackberry Jam, Featured, Julian Woodrow, Prodigy Camp, Singing Groups, Thilo BerndtTags Adrian Chirtea, artist, Blackberry Jam, boy, Boys, Desiree Hazleton, End of the Night, Julian Woodrow, Kris Orlowski, Music, musicians, New Music, Noah Gundersen, original, Prodigy Camp, Rick Stevenson, Rivenmaster, Seattle, singers, Singing Duo, Sixteen Year Old, song writers, teen camp, teens, Thilo Berndt, Twins, Washington, Young, youth
Carson Lueders Washington's Wonder Boy!
"I hope to be a positive influence and role model to others through my music and my actions."
Singer, Songwriter, Performer Carson Lueders
It's been a big year of growth for Carson Lueders and his music since first appearing here on Rivenmaster's Place. Carson's fan base has exploded and is reaching around the globe. His YouTube channel continues to gain new subscribers daily and his fan base is now made up from faithful Carson Lueders fans from 109 different countries! (There are 196 total countries so that's over ½ the world watching Carson's videos) It took about 3 years to get his 1st million YouTube views but only 3 months to get his 2nd million!!! Now he has gone over the 3 million mark averaging 10-20K views a day.
Because Carson is so young, having just turned 11, he seems to be standing out and separating himself from the pack of older teen boys that are competing in the saturated music market. He is constantly being compared to other boys in the industry and often being called the next Justin Bieber, little Cody Simpson, or baby Niall Horan. But many of his fans assure him he is not the next of anything but the FIRST & ONLY Carson! Everyday fans send him words of encouragement, compliments and even marriage proposals. Carson appreciates it all, including all the fan videos and picture collages.
Carson has been playing and performing since age five. He has been a guest on local radio since age six, and has been featured on the local news throughout the years. At just the age of nine he also won a national songwriting contest.
Although he started out playing mostly country music, Carson is now leaning more towards pop music. Some have even said that Carson could be a cross over artist like Taylor Swift.
His Mother exclaimed;
"It's been a great honor for many artists to acknowledge and complement Carson on the covers songs he has done. Some artists including Keith Urban, Aaron Carter and Australian teen Cody Simpson have even helped to promote Carson's music through social media sites such as Facebook and Twitter."
I asked Carson if he would do an exclusive interview for this article and I'm pleased that he took the time to do so. The following is an excerpt from that interview:
Continue reading "Carson Lueders Washington's Wonder Boy!"
Author RivenmasterPosted on 25-08-2012 14-12-2013 Categories Carson Lueders, Young Male Artists A-CTags Aaron Carter, Backstreet Boys, Biking, boy, Carson Lueders, Cody Simpson, Disney, Eleven year old, guitarist, Keith Urban, Mary J. Blige, Miley Cirus, Motocross, Radio Disney, singer, songwriter, Spokane, Talent, treble, Tricks, vocalist, Washington, Young, youth


For university students, the second and third year of university generally indicates that you will be living in a house with other fellow students. While this can be one of the most beneficial years in your early life, learning to live with new people and how to deal outside your familial home can, at the same time, be an absolute nightmare.
The first thing I found difficult about house hunting was that it had to be done so early: you move to university in late September/early October, and have had to have decided your potential housemates by the latest of December or January. This undoubtably adds pressure on your first few months of university where you don't really know anyone too well. I f you meet people you automatically click with, then that's great, but when you're thrust into an environment of new people in halls it's very difficult to find people who you will still get along with 2 months down the line. I have heard of many people who were friends in Freshers' Week and then never spoke again – I, similarly, had intended at one point to live with my hall mates, but a few months in, as nice as they were, we just knew we had nothing in common. While some people you meet in halls may be friends for life, I personally drifted between many friendship groups and didn't really establish a solid group of friends with shared interests who I trusted until about March of first year – when it was undoubtedly too late. Is it not unfair to make students decide in January who they will live with in September for a year?
I have seen many people rush into housing decisions which ultimately backfired on them, and conversely people who have had fantastic years. I was unfortunately the former so my second year, despite living with one of my best friends, was uncomfortable and tense. You learn a lot about yourself when you live in a student house for the first time, far more than in halls, and also a lot about other people. The key phrase 'you never know somebody unless you live with them' definitely comes into play here: you discover habits you never knew people had, and these – no matter how small or large, can definitely be a factor. Many people I knew discovered people's drug habits, girlfriends or friends who would live rent-free and never leave, people who never wash up, people who wash up incessantly, people smoking in the house… and I could continue, but you get the idea. The thing is is that you need a deal breaker – some people are fine with the bathroom smelling like marijuana, will this would drive others up the wall. There is no one I know who has got on really well with all their housemates all the time and everyone is bound to annoy each other at one point.
The key, in my opinion, is finding balance. But I do believe in 'less-is-more': there seems to be a tendency in first year to live in BIG houses with LOADS of people (I know a girl who lived with 10 people) which is perhaps fine if you like being surrounded by people and can work, but it also poses a lot more people with potentially a lot more problems. I would recommend living in smaller houses of about 3-5 people if you can, as the most harmonious houses I have heard of seems to be around that number.
Now obviously everybody is different: you may have chosen brilliant people you have got on well with within a manner of weeks, and found the house of your dreams where everyone is calm and gets on. I think the best houses are when everybody has their equal say – delegate tasks between each other, agree on the prices of the houses you are looking for and potential deal breakers, such as a washing machine/bath/dishwasher. I hate the idea of a 'cleaning rota', which I believe is slightly immature but it would work for some people – I had experience where cleaning was very imbalanced, and it became a much bigger issue than it needed to be. I have spoken to many people who felt they were forced or rushed into a decision and I do believe in spending the time discussing everyone's point of views and being direct and honest. In arranging our house for fourth year we have constantly discussed everything in a secret group in Facebook, and this has made me feel a lot more happy and in control of my situation, and quite calm in entering my fourth year.
I feel very fortunate that I have had a year abroad and time to reflect on my housing situation when I go back to university in fourth year. I definitely would not have enjoyed staying in the same location, at the same university for three years in a row. If I had I would have definitely moved houses for third year regardless of whether I loved or hated my second year house, because I knew there were elements (such as price) where I could not have stayed longer. I also feel lucky that I did stay in student halls again in Strasbourg – which was filthy and where I was robbed, and I will now have the experience of living in a student flat in Vienna with two Austrian girls, which I am excited about, because it gave me more insight and experience.
I know I am now reflecting on my experiences at 22 years old, a completely different situation to an 18 year old who is looking for their first student house, but I do with the benefit of hindsight say these things: do NOT rush into a situation you're not happy with, always discuss your deal breakers, make sure everyone has their say, learn to compromise, and unless you're the sort of person who likes living with a lot of people, consider splitting the groups up a bit. Also think – yes, they are my best friend now, but are they a best friend for life? Be objective and don't panic. Yes, there is a scramble for houses which I find unfair, but there will always be options, and ultimately a decision you make very quickly will affect at least a year of your life.
Have you had any problems with student housing? Did you have the best time in your years with other students? Are you looking for a student house at the moment and have any doubts? Are there any other problems you have faced? Or, conversely, am I being too negative? I'd love to hear all your views, as usual, below!


Conversations were recorded between Mohammed Nisar Khan, known as Meggy, and visitors he received while on remand in prison, Bradford Crown Court heard on Tuesday.
Detective Sergeant Zaheer Abbas, of West Yorkshire Homicide and Major Enquiry Team (HMET) said he was tasked to oversee the operation to covertly record prison phone calls and visits of Khan and co-accused Tony Grant.
Khan was in HMP Hull at the time and Grant in HMP Leeds, DS Abbas told the jury.
The calls and visits were recorded, listened to and transcribed, and parts played to the jury. The names of the visitors were not disclosed to the court.
Khan, 41, of Holme Lane, Tong, Bradford, and Grant, 39, of Queens Road, Bradford, deny murdering Amriz Iqbal and attempting to murder Adnan Ahmed in Sandford Road, Bradford Moor, on October 3.
They also deny conspiracy to pervert the course of justice, along with Salman Ismail, 31, of Hollin Road, Shipley, Bradford, and Nadeem Khan, 35, of Gledhow Wood Road, Roundhay, Leeds.
Mr Iqbal, 40, a father of three, of Curzon Road, Bradford Moor, was fatally injured when his head struck a hard object after he was thrown in the air. Mr Ahmed, 32, dislocated his shoulder in the impact.
Prosecutor Peter Moulson QC alleges that a silver Kia Sedona deliberately accelerated towards the two pedestrians when they were in clear view of the driver.
Tony Grant's barrister, Tim Raggatt QC, has told the jury there was "no issue" that his client was in the front seat of the vehicle during the collision.
In a secret recording at Hull Prison in November last year, Mohammed Nisar Khan said he was not in the vehicle at the time.
"An hour before, I got dropped off at home," he states.
Khan also says: "The only thing they've got is me putting petrol in the car.
At one stage, Khan's visitor refers to the passengers in the Kia Sedona at the time of the fatal collision.
"Clutching at straws," his visitor says, referring to the prosecution case.
"Yes, that just shows how desperate they are," Khan replies.
He then again states that he was not driving the vehicle.
Grant says the vehicle has been picked up on CCTV when it is being refuelled.
"It's only circumstantial evidence," he later states.
Grant goes on to say: "I can't name anyone. I ain't going on that route.
If he does, he'll "get his legs broke," he states.
"How many was in the car?" asks a visitor.


UPPERROOM has released its fourth recording and first full-length album, To The One, through The Fuel Music. Available now at iTunes, Apple Music, Spotify, Amazon.com, Google Play and more. The new full-length recording captures nine anthems that have inspired not only the members of UPPERROOM, the church in Dallas' creative Design District that started in 2010, but also millions more around the globe.
The album further features the title track that is meant to magnify the majesty of Jesus, "Healer," a song inspired by Psalm 68 that expresses how God heals even in the aftermath of grief, "You and You Alone,"a grateful anthem that breaks through the wiles of tribulation and struggles in our daily lives, and "Washed," which declares the truth of victory over sin and failure.


text:
Dotson is a Welsh surname originating from the Cheshire region. This surname is a patronymic of the Middle English name "Dodde." Originally derived from the Germanic root "dodd" meaning "something rounded", used to denote a short, rotund man . Notable people with this surname include:

Alphonse Dotson (born 1943), American football player
Amber Dotson, American country singer
Bob Dotson, American broadcast journalist
Carlton Dotson, American college basketball player and murderer
Chastity Dotson, American actress
Damyean Dotson, American basketball player
Demar Dotson (born 1985), American football player
Devon Dotson (born 1999), American basketball player
Earl Dotson (born 1970), American football player
Gary Dotson, American exonerated of a criminal conviction by DNA evidence
Jahan Dotson (born 2000), American football player
Jimmy Dotson (1933–2017), American blues singer, guitarist and drummer
Kevin Dotson (disambiguation), multiple people
Lionel Dotson (born 1985), American football player
Richard Dotson (born 1959), American baseball player
Santana Dotson (born 1969), American football player
Sam Dotson (born 1970), American police commissioner in St. Louis

See also
Dotson, Minnesota
Dodson (disambiguation)

redpajama_set_name: RedPajamaWikipedia


This necklace is stylish and class. You can wear for any occasion.
I thank you kindly read my general conditions of sale before ordering.
Feel free to contact me for any questions on this item or customization.


Ramblings of an Inspired, Lazy Mom: This Ramadan.
Hey my sweet readers. Looks like I have been totally missing on the blog since before Ramadan started. But now that the first week of fasting has gone by, I might be getting the hang of things, somewhat. Happy Ramadan to all of my Muslim readers. Wishing this month brings peace, blessings, and Allah's guidance your way. Ameen.
Just wanted to share some Ramadan related links that have been inspiring me.
- Loving this Back2Quran series where they are adding summaries of Quranic Surahs.
- This post by Aisha Saeed about supporting books on Ramadan and Eid for children.
- 30 days of beautiful Ramadan inspirations via Times.
- Love the tips shared on Productive Muslim to have a Productive Ramadan.
- Loved President Obama's message to Muslims on beginning of Ramadan. Here's a link to the video too.
Plus for new readers, more Ramadan posts from the past.
- When I shared ideas on making your own Ramadan traditions and memories.
And throughout this month I will be pinning inspiring ideas and articles here. Check them out.
Thanks for reading and stopping by. Stay inspired and have a lovely Ramadan.