text:
Q: Nginx uwsgi (104: Connection reset by peer) while reading response header from upstream Environment is Nginx + uwsgi.
Getting a 502 bad gateway error from Nginx on certain GET requests. Seems to be related to the length of the URL. In our particular case, it was a long list of GET parameters. Shorten the GET parameters and no 502 error.
From the nginx/error.log
[error] 22113#0: *1 recv() failed (104: Connection reset by peer) while reading response header from upstream, client: 192.168.1.100, server: server.domain.com, request: "GET <long_url_here>"

No information in the uwsgi error log.

A: I was getting the same nginx error and also there was no information in uwsgi log. The problem was that in some cases the application was not consuming the whole request body as advised in http://uwsgi-docs.readthedocs.org/en/latest/ThingsToKnow.html:

If an HTTP request has a body (like a POST request generated by a form), you have to read (consume) it in your application. If you do not do this, the communication socket with your webserver may be clobbered. If you are lazy you can use the post-buffering option that will automatically read data for you. For Rack applications this is automatically enabled.

Of course, this is not a problem in your case, but it may be useful for others who are getting the same nginx error.

A: We just need to increase the attribute "output_buffering" value, in php.ini, to a greater value like 65535 or another appropriate value.

A: After spending a lot of time on this, I finally figured it out. There are many references to Nginx and connection reset by peer. Most of them seemed to be related to PHP. I couldn't find an answer that was specific to Nginx and uwsgi.
I finally found a reference to fastcgi and a 502 bad gateway error (https://support.plesk.com/hc/en-us/articles/213903705). That lead me to look for a buffer size limit in the uwsgi configuration which exists as buffer-size. The default value is 4096. From the documentation, it says:

If you plan to receive big requests with lots of headers you can increase this value up to 64k (65535).

There are many ways to configure uwsgi, I happen to use a .ini file. So in my .ini file I tried:
buffer-size=65535

This fixed the problem. You can adjust that to taste. Maybe start with the max and work back until you have an acceptable value, or just leave it at the max.
This was frustrating to track down because there was no error on the uwsgi side of things.

A: When we receive a message like (104: Connection reset by peer) while reading response header from upstream, most often, we could blame the upstream side of this kind of error.
As described, the connection was reset by the upstream peer, not by nginx itself. Nginx as a client can barely do anything to make it right.
I'm suspecting if modifying buffer-size will do the magic. Basically the command changes the buffer size where response headers are cached. This would take effect when the response header is too big, of which case we receive a message saying upstream sent too big header while reading response header from upstream, and that is totally different thing from connection reset by peer.
Since this kind of error is trigger randomly, I would suggest you check whether nginx uses keepalive when talking to upstreams. If this was the case, the connection might be reset by upstream server when the idle timed out whereas nginx had no idea that the connection had been dropped, hence forwarding the request using the same connection.
There's no elegant solution to fix it as far as I know. You could do retry or set a keepalive_timeout value to the upstream connection pool in nginx to avoid the problem.
referencing:
Apache HttpClient Interim Error: NoHttpResponseException
http://tengine.taobao.org/document/http_upstream_keepalive_timeout.html

A: --post-buffering 32768
worked for me as suggested (and discouraged) here NGINX + uWSGI Connection Reset by Peer
I don't have time to investigate it further at the moment (quick prototyping mode :), but since it took me a lot of time to find this hack, it might be worth posting here.

A: It doesn't come up occasionally.
I guess the most possible reason of that is the size of your php-fpm.log is oversize. Try to change your log_level to upper level in php-fpm.conf and clear the logs.
Anyway, it works for me.

A: This can happen if your request/response headers are quite large.
To fix it, in /etc/uwsgi/apps-available/your-app.ini add buffer-size=65535

A: You need to re-install PHP:
apt-get install --reinstall php5-fpm


text:
Land Use & Development
Plans & Policy
King County's Comprehensive Plan Major Update Finds Approval
Stephen Fesler
The Metropolitan King County Council met last week to discuss and vote on the County's Comprehensive Plan major update, a process that occurs once every four years. In a brief three weeks ago, we outlined a variety of land use and zoning changes proposed at the committee review level. The package of amendments proposed at that time were approved at committee hearing two weeks ago, but further changes were proposed at last week's full County Council meeting. The proposed amendments to the approved Comprehensive Plan are summarized below, but of interest to most urbanists are land use changes. The Metropolitan King County Council voted on two primary amendments related to that topic, but by and large the approved Comprehensive Plan contracts King County's Urban Growth Area–though there are minor changes related to very small notch expansions–and increases infill development capacity within pre-existing Urban Growth Areas.
King County Looks Toward Land Use Changes
Amendment 1: Omnibus Technical Amendments
Councilmember Rod Dembowski's Amendment 1 was an omnibus amendment to address technical changes to the text of the proposed Comprehensive Plan related to agricultural lands and delay of the Skyway-West Hill area planning study. The amendment passed.
Amendment 2: Growth Targets
Councilmember Kathy Lambert had originally proposed to make a technical amendment to the growth targets appendix for the Urban Growth Area.
Key factors used in setting the UGA include population forecasts, growth targets, and land capacity. Population forecasts are predictions about future behavior based on past trends. Growth targets are a jurisdiction's policy statement on ((how many)) the minimum number of net new housing units it intends to accommodate in the future based on population forecasts and the expected size of the average household. Land capacity is derived from an estimate of vacant land plus the redevelopment potential of land already partially developed or underutilized. Discount factors are applied to the estimate of land capacity to account for probable constraints to actually developing the land.
Councilmember Lambert noted that local jurisdictions traditionally treated apportioned growth targets as a floor instead ceiling, but that recent changes to the region's VISION 2040 plan has turned the head on that thinking. Growth targets are projections of population, housing, and jobs that are apportioned through a collaborative process by cities, counties, and the Puget Sound Regional Council, the steward of VISION 2040. Councilmember Lambert, however, expressed particular concern that some cities–like North Bend–have been forced to hold off growth for long periods of time and even turn away certain types of jobs to meet the goals of the regional vision. In her remarks, Councilmember Lambert said that her philosophy is to allow local jurisdictions decide where and how much growth they should take on with the understanding that growth targets aren't an upper maximum.
Councilmember Lambert's concerns arguably have recently manifested. Earlier this year, the PSRC put pressure on outlaying jurisdictions like Carnation and Covington to curb their proposed infill policies and development regulations, or risk decertification of their Comprehensive Plans. The threat of decertification could mean that those jurisdictions would be denied scarce federal transportation dollars that flow through the PSRC. But the intent of the growth policy for outer urban jurisdictions is to slow growth outside or near the edge of the central Urban Growth Area in King County to focus most of the growth in Metropolitan, Core, and Larger cities.
While Councilmember Lambert withdrew her proposed amendment, it would have had the effect of setting growth targets by the King County Growth Management Planning Council as a minimum as opposed to a maximum, in much the same way that Seattle is treating its updated Comprehensive Plan.
Amendment 3: Revising Development Code Language
Councilmember Dembowski proposed a technical amendment to revise the County's development code so as to align language related to "Rural Area" and "Natural Resource Lands" that were incorporated in the new Comprehensive Plan by the TrEE Committee earlier in the legislative process; the amendment passed.
Amendment A-1: Omnibus Amendment
Councilmember Dembowski offered another omnibus amendment that focused on an updated executive summary statement, minor language revisions on topics of sustainable farming and land use subarea studies, wholesale policy changes surrounding the issues of gun violence and limiting lead exposure, delaying the subarea planning work for the Skyway-West Hill area until 2017, and adding a water study to the County work program in response to the recent Hirst Decision (Whatcom County v. Western Washington Growth Management Hearings Board) by the Washington State Supreme Court.
The latter addition to the work plan is particularly important from a land use perspective since the court case deals with permit-exempt wells in rural areas, adequacy of in-stream flows and water availability, and the inherent intersection of policy in development codes and Comprehensive Plan. The amendment set a timeline for an initial report on water policy for December 1, 2017, followed by a final report and transmittal of policy amendments to the Comprehensive Plan by July 1, 2018. The amendment passed as amended.
Amendment A-2: Water Availability
Building upon Amendment A-1's water study, Councilmember Lambert offered an amendment that would require County planners, as part of the study, to "…analyze methods to accommodate current zoning given possible water availability issues and will look at innovative ways to accommodate future development in any areas with insufficient water by using mitigation measures (e.g. water banks)." The amendment passed.
Amendment A-3: Amendment to Attachment A
As noted above for Amendment 3, the purpose of that amendment was to bring consistency between select section of the County's development code with the Comprehensive Plan. Amendment A-3 was the parallel Comprehensive Plan text amendment to revise language in the Comprehensive Plan to use the "Rural Area" and "Natural Resource Lands" terminology and topics. Sponsored by Councilmember Dembowski, the amendment passed.
Amendment A-4: Fully Contained Communities
Redmond Ridge East as seen from above. (Google)
Councilmember Lambert had planned to offer an amendment to strike language related to full contained communities (i.e., Redmond Ridge and Redmond Ridge East) from the Comprehensive Plan, but made a motion to withdrawn it. Before doing so, however, Councilmember Lambert explained why she felt it was important to revisit the issue in future years:
We had an employ come up this morning and say "I love living in a masterplanned community that I just moved to." I hear that often from people who live in fully contained communities. Fortunately, most of them are in my district and people love them, but we've decided that we are not going to build any in the future.
The language as it is written is pretty harsh right now and I was trying to get it softened because we don't know in the future exactly what the future may bring. And if you read yesterday's Seattle Times, which I'd like to talk about at the end, it's pretty startling what could happen if an earthquake hit this area, and we may want to build some fully contained communities.
So I am sad that we have so abrupt–I think is the right word–on how we are going to deal with this type of housing construction in forming communities. It is a great way of having people be able to work and play and live in a close proximity.
The adopted language (Policy U-181) in the Comprehensive Plan states:
Except for existing Fully Contained Community designations, no new Fully Contained Communities shall be approved in King County.
Amendment A-5: Rural Area Policy On Business Activities
Councilmember Lambert proposed three-word change to a Comprehensive Plan policy in the Rural Areas and Natural Resources Element. The amendment centered on the phrase "for nearby residents" (see below) which is an acknowledgement that non-residential uses that provide local products and services should not be scaled for larger markets (e.g., Costco, Walmart, or even Safeway).
Nonresidential uses in the Rural Area shall be limited to those that:
a. Provide convenient local products and services ((for nearby residents));
b. Require location in a Rural Area;
c. Support natural resource-based industries;
d. Provide adaptive reuse of significant historic resources; or
e. Provide recreational and tourism opportunities that are compatible with the surrounding Rural Area.
Councilmember Lambert expressed concern that the policy was unenforceable and unfair to rural residents and business owners.
Planning staff were called upon by Councilmembers to clarify application of the policy. Staff noted that the specific text constituted policy contained within the Comprehensive Plan–policy that has existed within the Comprehensive Plan since 2004–but had been proposed for further "tightening" earlier in the legislative process. As a policy, the language essentially serves as a box that subsequent development regulations (codified land use ordinances) must be formed within by decision-makers. Staff did note, however, that there are instances of land use permitting that decision-makers (e.g., administrative review staff, Hearing Examiner, or County Council) may rely upon the policy–through say conditions for a Conditional Use Permit or SEPA–but that the policy would only be considered in the larger context of decision criteria, development regulations, and other relevant policies.
The amendment failed on vote of the Metropolitan King County Council.
Amendment A-6: Watershed Planning
King County is in the process of working through a watershed planning effort specific to the Snohomish Valley Agriculture Production District. The process was included as a policy in the Comprehensive Plan detailing the intent to implement related recommendations that derived from the Snoqualmie Fish, Farm, and Flood Advisory Committee. The policy sets an expectation that the committee will continue to monitor the progress of task forces and evaluate County's watershed planning approach for the agricultural region, and that permanent policies will be recommended for the next major update to the County's Comprehensive Plan. Councilmember Lambert offered an amendment to clarify that the planning approach and recommendations for the Snohomish Valley is unique and should not "broadly applied in other Agricultural Production Districts." The amendment passed.
Amendment A-7: Public Spending
King County has a policy (Policy F-208) that speaks to how the County prioritizes public spending to facility local needs. The original version of the policy spoke only to investments related to growth and coordination through Capital Facility Plans (CFPs). CFPs are mandated to be updated annually by the Growth Management Act to ensure that the delivery of public services are adequately aligned with goals and objectives of the Comprehensive Plan. Councilmember Lambert offered an amendment to indicate the County's intention to maintain existing services outside of the Urban Growth Area–an obligation that the County has:
Public spending to support growth should be directed to the Urban Growth Area and to maintain existing unincorporated infrastructure, and should be prioritized ((and coordinated)) through the Capital Facility Plan((s)) to comply with the concurrency requirements of the Growth Management Act.
There was some concern amongst councilmembers over a change to the text and the implications that it might have, but the amendment ultimately passed.
Amendment A-8: Unincorporated Area Services
King County has a policy (Policy F-209a) that outlines some of the local services that the County will provide for unincorporated areas. These include: permitting, courts, land use controls, law enforcement, parks, transportation, natural resources management assistance, and surface water management. Councilmember Lambert wanted to add one item to the list, that being "economic development." The amendment passed.
Amendment B-1.A and B-1.E: Amendment to Fairwood A
Future Land Use Map change proposed in Fairwood. (King County)
For a little background, a series of four parcels were proposed to received Future Land Use Map and zoning map amendments. The King County Executive's Recommended Plan earlier this year only proposed to increase residential densities on the northern most parcel from Urban Residential Medium (um) to Urban Residential High (uh) with a corresponding rezone from R-6 to R-18. Meanwhile, the southern three parcels were proposed to remain unchanged.
The Metropolitan King County Council's land use planning committee proposed an amendment to the redesignate and rezone the southern three parcels of land as well, subject to specific conditions and denoted on the proposed zoning map with a special "P" suffix. The conditioned zoning would required any future multi-family residential project to include some combination of senior residential single-family, senior citizen assisted housing, day care facilities, and nursing and personal care facilities, or if none of those, the project would have to provide at least 20% of the new residential units as affordable for moderate-income households.That amendment was approved at the committee level.
Proposed zoning for the Fairwood parcels. (King County)
However, Councilmember Reagan Dunn, who represents the area in Fairwood, sought to offer an amendment (B-1.A) that would have:
Removed the the uh land use designation to keep the parcels as um;
Removed the R-18 zoning to the parcels as R-6; and
Removed the specific conditions set on the properties.
Councilmember Dunn cited wide ranging concerns of residents in the area, such as lighting, crime, building heights, environmental impacts, and traffic congestion resulting from higher density development, despite development likely taking the form of senior housing. Councilmember Dave Upthegrove spoken in response to Councilmember Dunn's comments saying:
If we aren't able to accommodate growth within the Urban Growth Boundary, then we're going to continue to have problems with housing affordability. Growth is coming whether we like it or not, just look at the statistics and growth in this region. The PSRC says that we will experience 25% growth in the next 25 years. This neighborhood and neighborhoods like it will be seeing increased…population density. That's why we have an urban growth area. There's things inside and outside. Change is difficult, I understand that….If I were going to have growth in my community, I would probably prefer it to have this level…[of] senior [housing desnity] which has lower…traffic patterns. I'd like to see a proposal like this one that has a significant set-aside–60% of the land preserved as greenbelt open space, 20% of the units affordable. And so I think if we get to the point that we're not able to accommodate increased density within our urban growth areas…that we'd have a real problem with having pressure on the urban growth boundary and rural areas.
The vote on amendment B-1.A failed.
Councilmember Dembowski then offered a friendly amendment (B-1.E) to address some of the concerns that Councilmember Dunn raised. Packaged into the amendment were additional conditions:
Requirements for a conservation easement along the western edge of the four properties;
Establishment of a maximum building height of 65 feet on the northern three parcels;
Limitations on permitted land uses for the northern three parcels to only single-family residences for seniors, senior citizen assisted living housing, senior day care facilities, and nursing and personal care facilities;
Establishment a sunset clause for December 31, 2023 for the Council-approved land use designation and zoning contingent upon submission of a development application; and
Requirements for a Conditional Use Permit public process that has light design review elements to evaluate issues like building design, lighting, parking and traffic impacts, and setbacks
The conservation easement would have to be recorded against the properties prior to development permits being applied for and would need to encumber all critical areas and a buffer area west of them to provide separation from lower-density residential areas adjacent to the site. The friendly amendment passed allowing the land use designation and rezone changes to occur on the properties.
Amendment B-2: Reserve at Covington Creek
The land use proposal for Reserve at Covington Creek. (King County)
A final land use amendment was offered by Councilmember Dembowski to amend zoning conditions attached to a Four-to-One development near Kentlake High School in the Black Diamond. The amendment proposed to:
Eliminate a pre-annexation agreement requirement with Black Diamond and instead condition future properties with a no-contest covenant for annexation;
Revise allowed densities on the property so that a maximum of 80 dwelling units is permitted and that the average density not exceed four units per acre on 50% of the site;
Add language that requires 160.53 acres be put into conservation status through various means (e.g., on-site conservation easements, purchase of Transfer of Development Rights, and conservation of high priority sites elsewhere in King County);
Eliminate a condition requiring consistency with Black Diamond development regulations; and
Revise language related to transportation concurrency.
The amendment passed.
Ultimately, the Metropolitan King County Council approved the amendment Comprehensive Plan ordinance, paving the way for the new ordinance to become effective once King County Executive Dow Constantine signs off. The next major update to the County's Comprehensive Plan will occur in 2020 with minor annual amendments in the intervening years.
Attachment A – King County Comprehensive Plan – 12-05-16 by The Urbanist on Scribd
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Stephen is an urban planner with a passion for promoting sustainable, livable, and diverse cities. He advocates for smart policies, regulations, and implementation programs that enhance urban environments by committing to quality design, accommodating growth, providing a diversity of housing choices, and adequately providing public services. Stephen primarily writes about land use and transportation issues.
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AJ December 14, 2016 at 9:51 am
Amendment 2 is a tough one for me. I get the policy position to hold the line on the UGB and to channel growth into the core cities, but if a city puts forward a smart, urbanist plan for development I think that should be encouraged.
Some quotes from the Times article:
"Covington is planning for a denser, more walkable downtown with six-story, mixed-use buildings that feature ground-floor retail and some affordable-housing units. But its Comprehensive Plan was rejected by the PSRC because it assumes almost three times as much growth in housing — 4,000 new units — as King County calls for in its targets, which Hart notes were set six years ago." – Covington is currently a classic suburb – all SF homes and strip malls. Wouldn't it be great to evolve it's commercial core into something more Urbanist.
"At the edge of Duvall, the city has approved plans for a 99-unit housing development on a former 34-acre farm. The project will feature higher-density, two- and three-story fourplexes, with trails and open space set aside for the public." Similar to my comment on planned communities – converting a farm into homes is textbook 'sprawl,' but if it's fourplexes that's denser than most of Seattle's SF zones!
Given the housing shortage in the region, I think we need to figure out how to have "good sprawl" in addition to robust infill growth in our growth centers.
Why no more planned communities (A-4)? While they are (usually) built on greenfields, and people need to drive (or park & ride) to job centers, they can be very pedestrian & bike friendly, with parks and school within walking distance.

redpajama_set_name: RedPajamaCommonCrawl


text:
HomeGamingPC GamingGameStop to host 'Mass Effect 3' Midnight Events
GamingPC GamingPlaystation 3xBox 360
GameStop to host 'Mass Effect 3' Midnight Events
By Dave McCarty
GameStop will host Mass Effect 3 Midnight Launch events across the U.S. on Monday, March 5. Over 3,600 stores will be open to sell the latest EA game priced at $59.99 for the standard version, and $79.99 for the Digital Deluxe Edition. Those who pre-order the game will receive exclusive bonus items including the N7 "Valkyrie" Assault Rifle and N7 "Defender" Armor. GameStop customers who purchase Mass Effect 3 before March 11 can also get $50 off a Kinect Sensor. The Mass Effect 3 DLC "From Ashes" is also available to pre-order for $9.99 (releasing on 3/6/12). Mass Effect 3 is published for Xbox 360, PlayStation 3, and Windows PC.
Previous article'The Twilight Zone' complete series coming to Blu-ray
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105680005 has 8 divisors (see below), whose sum is σ = 126887832. Its totient is φ = 84496128.
The previous prime is 105679979. The next prime is 105680011. The reversal of 105680005 is 500086501.
It can be written as a sum of positive squares in 4 ways, for example, as 17489124 + 88190881 = 4182^2 + 9391^2 .
It is not a de Polignac number, because 105680005 - 219 = 105155717 is a prime.
It is a super-2 number, since 2×1056800052 = 22336526913600050, which contains 22 as substring.
It is a polite number, since it can be written in 7 ways as a sum of consecutive naturals, for example, 5857 + ... + 15673.
It is an arithmetic number, because the mean of its divisors is an integer number (15860979).
Almost surely, 2105680005 is an apocalyptic number.
105680005 is a deficient number, since it is larger than the sum of its proper divisors (21207827).
105680005 is an equidigital number, since it uses as much as digits as its factorization.
105680005 is an odious number, because the sum of its binary digits is odd.
The sum of its prime factors is 11975.
The product of its (nonzero) digits is 1200, while the sum is 25.
The square root of 105680005 is about 10280.0780639059. The cubic root of 105680005 is about 472.7856376913.
The spelling of 105680005 in words is "one hundred five million, six hundred eighty thousand, five".


Everyone was freaked out when the candles broke off from their waxy mother and started to walk around. Everyone.
But they were beautiful company at the party, dancing and mingling wherever it was safe….and so they were welcomed into the family.
And so the fun began……..


text:
A Nederlandse IJshockey Bond (NIJB; em português: Federação Neerlandesa de Hóquei no Gelo) é o órgão que dirige e controla o hóquei no gelo dos Países Baixos, comandando as competições nacionais e a seleção nacional.

Organizações dirigentes do hóquei no gelo
Organizações esportivas dos Países Baixos
Organizações esportivas fundadas em 1933

redpajama_set_name: RedPajamaWikipedia


Objective To analyze the influence factors of medical expenses of the elderly, explore the effect of different health in- surance on medical expenses and discuss how the medical insurance as the main payment to influence medical expenses. Methods Kruskal- Wallis test and general multivariate linear regression model were used to analyze the influence factors based on the data from CLHLS in 2011 - 2012. Results The participating in the new rural cooperative medical insurance scheme (NCMS) and urban residents basic medical insurance (UR-BMI) were significantly related to the level of the elderly's medical fees, medical expenses of the elderly were mainly paid by themselves, the NCMS and commercial medical insurance as the main payment eased the pressure of medical expenses for the elderly. Con- clusions The expanding coverage of basic medical insurance and reimbursement ratio of the NCMS, encouraging the elderly to participate in commercial medical insurance, expanding social assistance institutions or pension institutions could alleviate the pressure on medical expen- ses for the elderly.


When Jo Symons was found to have cancer, there was an extra complication: doctors could not tell what type of cancer she had.
Tumors were found in her neck, chest and lymph nodes. But those tumors had spread there from someplace else, and her doctors could not determine whether the original site was the breast, the colon, the ovary or some other organ. Without that knowledge, they could not offer optimal treatment.
Such mystery tumors are estimated to account for 2 percent to 5 percent of all cancer, or at least 30,000 new cases a year in the United States, making them more common than brain, liver or stomach cancers. For patients, such a diagnosis can amount to a double agony — not only do they have cancer, but doctors cannot treat it properly.
"You don't believe that in the 21st century it is possible for the medical profession not to know where the cancer is coming from," said Ms. Symons's husband, John.
But now 21st-century medicine may help. New genetic tests may pinpoint the origin of the mystery tumors. The tests, which cost more than $3,000 each, still need to prove their worth better, experts say, though some of them are hopeful.
"I can tell you there have been several patients I've had where their therapy was altered" based on the test results, said Dr. F. Anthony Greco, director of the Sarah Cannon Cancer Center in Nashville and a leading expert on cancer of unknown primary, or CUP, as the mysterious disease is formally known.
Dr. Greco said it appeared that in many cases the primary tumor was too small to be detected, and in other cases it may have disappeared. "Why the primary tumor didn't grow and get bigger we have no idea," he said.
Such tumors are typically found in the liver, the lymph nodes or the bones, but can be in other places as well. But when tumor samples, taken either from a biopsy or from surgical removal, are examined under a microscope, they do not resemble cancers that would originate in the places they are found. Nor do the cells clearly resemble those from breast, colon or other types of cancer.
The problem is that cancers are treated based on their origin. If a cancer that originated in the breast is found in the liver, it is still classified as breast cancer and treated with breast cancer drugs.
Lacking such a classification, doctors can use drugs that work for a variety of cancers. But such treatment presumably is less effective than one using drugs matched to the type of cancer.
So the discovery of an unclassified cancer often sets off a frantic search for the original tumor.
"I had every test out there — PET scan, M.R.I., colonoscopy, mammogram — I even swallowed a pill with a camera on it" to take pictures of the digestive tract, Lori Young of Huntsville, Ala., wrote on a Web site for people with cancer of unknown primary. But her original tumor could not be found.
Ms. Young, 39 and a mother of two, was found to have tumors that had spread to her liver in October 2007. She is being treated with drugs typically used for lung cancer.
Patients say the inability to find the original tumor adds to their anxiety.
It is even hard for patients to explain their situation to friends and family, or to get advice from them. The new tests may solve some mysteries. Already there are four such tests on the market, and at least one other is being developed.
Generally the tests analyze which genes are active or inactive in a tumor sample. They compare that genetic fingerprint with the fingerprints from known tumor types, trying to come up with the best match.
The Tissue of Origin test from Pathwork Diagnostics of Sunnyvale, Calif., measures the activity of 1,500 genes. The CancerType ID, from BioTheranostics, based in San Diego, looks at 92 genes. The CupPrint test from Agendia, which is based in the Netherlands, looks at about 500 genes. That test is not available yet in the United States.
The MiRview Mets test from Israel-based Rosetta Genomics takes a different approach, analyzing microRNAs, which are tiny snippets of genetic material that help control the activity of genes.
Only the Pathwork test has been approved by the Food and Drug Administration, although the approved version has been superseded by a more practical version that is not approved. Tests can be offered by laboratories without F.D.A. permission, even as they are still being validated.
The tests are generally 80 to 90 percent accurate, according to published studies.
But that is when they are used on tumors whose origin is known. In practice, the tests would be used on tumors whose origin is unknown. And those may by their very nature be harder to classify, said Dr. Lawrence Weiss, chief of pathology at the City of Hope cancer center in Duarte, Calif.
A study published last September in The Journal of Clinical Oncology reported that the Agendia test correctly classified 83 percent of known tumor samples. But the test could classify only 64 percent of unknown tumors.
And of course, if the tumor origins are truly unknown, how does one even know if the genetic test is coming up with the correct answer?
One way, Dr. Greco said, is that there are rare cases in which the primary site becomes known months later, like when a patient suddenly starts feeling pain at that site.
Dr. Greco collected the original biopsy samples from some of these patients and found the BioTheranostics test to be about 70 percent accurate in classifying the tumors, compared with only 10 percent to 20 percent for the most advanced pathology techniques.
How valuable the tests will be still remains to be seen. Some biopsies do not provide enough genetic material for analysis. Ms. Droman, for instance, could not get any answer from the Rosetta test, and Mr. Kargul could not get one from the BioTheranostics test.
Dr. Weiss of City of Hope said that pathologists now used antibodies that can latch onto telltale proteins in the tumor. That technique, called immunostaining, can classify about two-thirds of tumors that would have been considered unknown primaries about 30 years ago, Dr. Weiss said. That leaves only one-third, or about 1 percent of all cancers, that might benefit from the newer genetic tests.
Still, for those patients, however many there are, any clue could be helpful. Dr. Martin A. Martino, a gynecologic oncologist at Lehigh Valley Health Network in Allentown, Pa., said he recently used the Pathwork test to classify a patient's tumor as ovarian. That allowed her to enroll in a clinical trial testing a new drug for ovarian cancer.
The real proof of the value of the tests would be to show that patients live longer after undergoing the tests, presumably because they would then receive treatment better matched to their tumors.
M.D. Anderson treats 250 to 350 patients a year with cancer of unknown primary. It is using the genetic tests in selected circumstances. "We try to ask ourselves, 'Is this information going to change the treatment we recommend for the patient?' " Dr. Abbruzzese said.
Jo Symons took the Agendia test, but not before being treated with two different chemotherapy regimes, both unsuccessful. The test showed that she had pancreatic cancer, so she was given chemotherapy for that cancer.
But pancreatic cancer is notoriously difficult to treat, and she died in September 2006, only seven months after her initial diagnosis. To help other patients, Mr. Symons set up the Cancer of Unknown Primary Foundation, also known as Jo's Friends, after his late wife (www.cupfoundjo.org).


We get the rainbows but not the cockatoo, (thankfully ) but they are so pretty. Great photos.
I never tire of sights like this in the garden. Lovely photos!
Our feathered friends are always fun to watch Sandi!
The cockies do make a ruckus don't they, but they are lovely to have around. We don't get the rainbow lorikeets, but the crimson rosellas make up for it. We are so blessed to have such colourful visitors to our gardens.


text:
Dirty, dirty
Got a question for Stewart Mandel – if Houston Nutt is a "certifiably dirty" coach by this standard…
… The definition of "dirty" seems to vary based on one's affiliation, but surely we can all agree on at least one designation: A dirty coach is willing to eschew his integrity if doing so might pay off in a couple more W's. He's not so much a winner as a survivalist. He's not even necessarily a rule-breaker because he creates his own loopholes.
… exactly where does Derek Dooley rank in the firmament of "dirty" coaches today?
Filed under Crime and Punishment, Media Punditry/Foibles
August 3, 2010 · 12:17 PM
Better as a Gator backup than a Georgia starter?
This post at A Bulldog in Exile, comparing Aaron Murray's and John Brantley's credentials, inspired a hypothetical. Presume for a moment that Murray succumbed to the charm of going to his state school and became a Gator instead of a Dawg. It's likely that he'd be backing Brantley up this season.
So here are my questions: were that the case, how many pundits do you think would be promoting the idea as the year progressed that Murray the backup, feasting on opponents at garbage time, would be good enough to start for "x" number of SEC teams? And how large a number would that "x" be?
I'll hang up and listen to your answers.
Filed under Gators, Gators..., Georgia Football, Media Punditry/Foibles
This is kind of a minor, yet fun, point to consider, but has anybody thought about how Walsh and Butler will do in the thinner air in Boulder?
Matt Melton has compiled some data on how Colorado's kickers have performed on kickoffs over the past two seasons which indicates that may not be a small factor:
The Air Up There
One of the most difficult variables to account for when evaluating home/road splits is schedule strength. Some teams may play better at home, not because they have a great homefield advantage, but because they happened to play much weaker teams at home. Similarly a reverse split could exist because team's road schedule was much easier. However, there is one facet of football for which the ability of the opponent has practically no effect on a team's performance. Kickoffs. I'm not referring to returns here, which has very much to do with the blocking and return skills of the opposing team. I'm talking about the action of kicking off and trying to force the opposing team to down the ball in their own endzone. Commonly referred to as a touchback by those in the know. In the past 2 seasons, Colorado has had 2 players kickoff for them, Aric Goodman and Jameson Davis. Goodman has converted 15 touchbacks in 53 kickoffs and Davis converted 15 in 48 kickoffs. Thus, as a team, the Buffs have combined for 30 touchbacks in 101 attempts. However, when we look at how they have performed at home versus on the road, one can easily tell Goodman and Davis have been aided tremendously by the thin air in their home stadium.
I think Fabris would have driven us crazy handling the challenge, were he still around.
Maybe Walsh will get a shot at kicking a 60+ yard field goal.
Filed under Georgia Football, Stats Geek!
"People who look to attack have more fun."
Don't hate on me for writing this, but Mark Bradley's post about the changes on defense is a worthy read, if only for the player quotes. An example:
… In 2010 Justin Houston was a defensive end, which means, in football argot, that he aligned himself by sticking his hand in the dirt. Now he's an outside linebacker, and not just any old OLB — he's the weakside backer, which was Lawrence Taylor's position and is DeMarcus Ware's.
Ware has had 64 1/2 sacks over five NFL seasons. Not coincidentally, he plays for the Dallas Cowboys, where Grantham was previously employed as the defensive line coach. Not surprisingly, he has become Justin Houston's model.
"I watch DeMarcus Ware almost every night," Houston said. "I've got my own personal cut-up [a DVD that isolates Ware]." Then this: "If I could be half as good … "
There's a chance Houston, who had 7 1/2 sacks as a down lineman in 2009, will double that number in 2010. If the 3-4 is built for anyone, it's for big men who can come hard off the corner. Asked how often he figures to blitz this season, Houston said: "It all depends on the game plan."
Were he designing the game plan, how often would he have himself blitz? Said Houston, laughing: "One hundred percent of the time."
Sooner or later, they always know the score in Montana.
One of the things I took a vacation from last week was Stewart Mandel's Mailbag, so I'm a little tardy reacting to this exercise in after-the-fact backpatting:
Georgia in '08, Ole Miss in '09. What team this year is most likely to be the "sexy" pick that falls far short of expectations?
— Jared, Columbus, Ohio
A little context: Georgia went 10-3 in '08, Ole Miss 9-4 in '09, and both played in semi-major bowls (Georgia beat Michigan State in the Capital One Bowl, Ole Miss beat Oklahoma State in the Cotton Bowl.) However, because the Dawgs had been touted as a preseason No. 1 team and Ole Miss as high as fifth, their seasons were considered letdowns. Yet, in neither case were people all that "surprised" by their "downfall" because most considered them "overrated" to begin with.
One question: how does a team that "most people" consider to be "overrated" (love those scare quotes, Stewart) get voted preseason No. 1 in the first place?
Filed under Georgia Football, Media Punditry/Foibles
Steele talks turnover margin.
Arkansas Expats has a three-part interview with Phil Steele worth reading in its entirety if you're interested in getting a handle on the Razorbacks' prospects this season (hint: he's pretty optimistic about their chances), but here's the Q&A exchange that grabbed my attention:
Expats: One of the bright spots last year was that they forced a lot of turnovers. Is that something that you expect to happen again or is that kind of a random occurrence?
Steele: I've done studies on turnovers since actually the first year of my magazine. I started an article called "Turnovers Equals Turnaround." Basically it shows that teams that are plus-double digit in turnover margin one year, about 75 percent of the time they have a weaker record the next year, which is a little disconcerting for me for Arkansas.
But keep in mind, if it is 75 percent, that still means there's 25 percent of the teams out there that actually are the same or improve the next year. So there are teams that are able to avoid that particular predicament.
You look at Arkansas in 2008, for example: they were 5-7, and they were minus-nine in turnovers. That basically qualified them for the "turnovers equals turnaround." They were one away from a double-digit [turnover margin].
Last year, they changed up to plus-15 and improved to 8-5. As mentioned, this is a team poised to be better than that. I don't think they're going to be plus-15 in turnovers this year. I would think the level would come down to more of a plus-3, plus-4. It's just the way my research has shown. There's very few teams that can put together back-to-back plus-double digit turnover seasons.
It will be interesting to see how Arkansas shapes up in that category.
Interesting, indeed.
If anything, Steele overstates the possibility that the Hogs repeat their plus-double digit turnover success in 2010, at least based on the conference's track record over the past eight seasons. From 2002 through 2009, that feat was accomplished only once, by Arkansas in 2002 and 2003.
Comments Off on Steele talks turnover margin.
Filed under Arkansas Is Kind Of A Big Deal, Phil Steele Makes My Eyes Water, Stats Geek!
Searels may not say much, but when he does…
Day 1 of fall practice is in the book. For some perspectives on what went on, you can read this, this and this, but I'm not really sure you need much more than Stacey Searels' summary:
"We really kicked butt in walk-through this morning. We were awesome. . . .Walk throughs, we are world-beaters." Then, sternly: "You don't walk through a football game."
I don't think there'll be a humility problem in fall camp this season.


What are Skopje's expectations from the Romanian presidency?
The Romanian presidency of the European Union is facing big challenges, however, as far as FYROM is concerned, there's a positive atmosphere in terms of the reforms and in terms of addressing the criteria for European integration. This is the opinion of the Romanian ambassador to Skopje, Viorel Stanil who presented the priorities of his country during this presidency.
"There are three key priorities for the Romanian presidency of the EU: the Union's activities regarding Western Balkan countries and the Union's enlargement policy, joint security and defence policies and Brexit", Stanil said.
As far as FYROM is concerned, Stanil said that Romania will support the positive decision to launch accession talks.
Deputy PM for European Affairs, Bujar Osmani says that the fact that the EU's presidency is being held by a friendly country in such an important period, is a positive thing.
"I hope that the Romanian presidency will enter the history of our country once we launch the accession talks with the EU", Osmani said.


text:
Das Dorf Schwenge ist eine Wüstung im heutigen Gebiet des Ortsteils Oberzella in der Stadt Vacha im Wartburgkreis in Thüringen.
Schwenge lag etwa einen Kilometer nördlich von Oberzella an der Ortsverbindungsstraße nach Vitzeroda.

Geschichte

Schwenge wurde am 31. August 786 erstmals erwähnt. Im Dreißigjährigen Krieg lag der Ort erstmals wüst.

1816 kam der Ort gemeinsam mit Vitzeroda, Abteroda, Gasteroda, Oberzella, Niederndorf und Heiligenroda von Hessen an Sachsen-Weimar. 1879 gab es im Ort vier Wohnhäuser mit 27 Einwohnern; 62,9 ha Gesamtfläche; davon Höfe und Gärten 1,6 ha; Wiesen 16,1 ha; Ackerfläche 38,3 ha. Wald 0,64 ha; Teiche, Bäche und Flüsse 0,01 ha; auf Wege, Triften, Ödland und Obstbauplantagen entfielen 6,18 ha.

Nach 1945 lag Schwenge unmittelbar an der innerdeutschen Grenze, die ab 1952 massiv befestigt wurde.

Am 3. Oktober 1961 wurden die ersten Bewohner im Rahmen der "Aktion Kornblume" zwangsausgesiedelt, am 12. bis 13. Februar 1974 mussten die letzten Einwohner den Ort mit der Begründung einer verbesserten Grenzsicherung verlassen. Am 15. Februar 1974 wurden die Höfe in Schwenge abgerissen und eingeebnet.

Weblinks
 Ortsbeschreibung auf www.widdershausen.de

Wüstung im Wartburgkreis
Geschichte (Vacha)
Geographie (Vacha)


The Bladen hacking jacket is a timeless jacket which looks great with a pair of cords, chinos or nowadays a pair of jeans!
The classic mens hacking jacket is available in two tweeds - the classic olive overcheck and the biscuit blue and red windowpane check, both of which are a 620 gram Supasax cloth and lined wih a gold satin lining and real horn buttons. The tradittional mens hacking jacket has three buttons, a tapered fit, ticket pocket and a single vent.
Founded in 1917, Bladen is committed to maintaining the highest standards of traditional craftsmanship and meticulous attention to detail. A Bladen jacket takes up to six weeks to create involving a highly skilled process of over 120 separate operations, many of them by hand.
In the current range Bladen have returned to their original heritage of high quality Scottish tweeds; very much a collection that is country orientated but is equally at home in town.
Natural Canvas interlining, including 100% horsehair.
Four piece chest set to ensure a near perfect lasting fit across the chest and shoulders.


Worcestershire Seconds had to be content with a point from their Second Eleven Trophy clash with Durham at Kidderminster which was abandoned because of rain.
There were several interruptions for rain but Durham finally totalled 283-5 from 35 overs before the final stoppage ended hopes of a positive result for either side.
Worcestershire have now a total of three points from their opening two games following their win over Unicorns at the same venue on Wednesday.
Durham elected to bat and openers Graham Clark and Jack Clark figured in an opening stand of 158 in 23 overs.
Graham Clark had an early let off, dropped at cover on nought from the second ball of the innings from Liam Smith.
He eventually made 104 from 74 balls with three sixes and 14 fours – one of four wickets for skipper Alexei Kervezee.
Graham Clark was dismissed for 64 from 68 balls with two sixes while Calum MacLeod provided even more impetus with 54 off 27 deliveries with four sixes and three fours.
But then the heavens opened and the game was finally abandoned at 5.45pm.


text:
Over Lin Wood's Election Lawsuit in Georgia
Appeals Court Grants Expedited Review
Epoch Times, by Mimi Nguyen Li
Posted By: earlybird, 11/26/2020 9:44:38 AM
The 11th Circuit Court of Appeals on Wednesday granted Lin Wood's emergency motion seeking an emergency review of a lower court's decision that had rejected his efforts to delay the vote certification in Georgia. However, the court said that the appeal could only proceed if Wood could address certain jurisdictional issues. Wood, an attorney with Trump's reelection campaign, announced on Twitter, "Thanksgiving Eve News! 11th Circuit granted my Emergency Motion for Expedited Review of lawsuit challenging validity of GA election procedure. (Snip) The appellate court presented Wood with two questions about jurisdiction (pdf): "Please address whether the district court's November 20, 2020 order denying the 'Emergency Motion for Temporary Restraining Order'
Reply 1 - Posted by: earlybird 11/26/2020 10:18:12 AM (No. 617062)
Included in this article is a narrative of legal remedies that Lin Wood has been pursuing in Georgia. We won't have heard about these on any evening news - even on Fox - nor will we have read about them in the mainstream news. Read it and you'll understand what I am talking about - and why I don't panic when I think "nothing's happening!!!!"
Reply 2 - Posted by: MDConservative 11/26/2020 1:20:39 PM (No. 617202)
It appears that the Woods and Powell filings parallel one another, attacking from different angles. Still, it all comes down to the legitimacy of the vote counting. The problem is that ultimately the court can do whatever it does, and the legislature will doubtlessly name its chosen electors under its Constitutional authority.
Reply 3 - Posted by: RedWhite&Blue2 11/26/2020 1:43:14 PM (No. 617214)
GUILTY Open up Gitmo Pack in the rat bastids! Four More Years!
Apparatchik John Kerry, Climate Czar 10 replies
The Pipeline, by Lisa Schiffren Original Article
Posted by earlybird — 11/27/2020 6:23:25 PM Post Reply
Suppose you are a man with a long history of personal mediocrity in important positions. You aren't quite as publicly toxic as, say, Hillary Clinton. But no one really respects you either. You're old, 76. You're definitely a "me too" lothario. You have said nothing notable in 35 years in the public eye, first as a U.S. Senator, then failed presidential candidate, and finally Secretary of State. Your biggest success was in being the face of Obama's Iran deal, the entire premise of which was to set up an untrustworthy, fundamentalist regime hell-bent on acquiring nuclear weapons,(Snip) So which job do you get in a Joe Biden Administration?
Pennsylvania Court Rejects Trump Appeal,
Campaign Lawyers Say It's 'On to SCOTUS' 15 replies
The U.S. Third Circuit of Appeals in Pennsylvania on Friday rejected President Donald Trump's campaign appeal in their challenge of the state's election results, a move that Trump's lawyers said will allow them to expedite their lawsuits to the U.S. Supreme Court. "The activist judicial machinery in Pennsylvania continues to cover up the allegations of massive fraud. We are very thankful to have had the opportunity to present proof and the facts to the [Pennsylvania] state legislature," Trump lawyers Jenna Ellis and former New York City Mayor Rudy Giuliani wrote in response. "On to SCOTUS!" they wrote, referring to the Supreme Court.
Live Updates: Iran's Top Nuclear Scientist
Killed in Attack, State Media Say 20 replies
New York Times, by Farnaz Fassihi Original Article
Posted by earlybird — 11/27/2020 11:10:03 AM Post Reply
Iran's top nuclear scientist, who American and Israeli intelligence have long charged was behind secret programs to design an atomic warhead, was shot and killed on Friday as he was traveling in a vehicle in northern Iran, Iranian state media reported. The scientist, Mohsen Fakhrizadeh, believed to be 59, has been considered the driving force behind Iran's nuclear weapons program for two decades, and continued to work after the main part of the effort was quietly disbanded in the early 2000s, according to American intelligence assessment.
Legal Group Files Lawsuit Challenging
Over 200,000 Ballots in Georgia 5 replies
A legal group on Wednesday filed a lawsuit alleging over 100,000 illegal votes were counted in Georgia, while tens of thousands of legal votes weren't counted. According to the suit, the estimated number of such votes exceeds 200,000. "Because of these irregularities, no one knows who really won Georgia's presidential election. So, the election result should be nullified and the appointment of the electors should revert to the state legislature, as provided in Article II of the United States Constitution," the 28-page document states. The Amistad Project of the Thomas More Society brought the suit on behalf of John Wood, president of the Georgia Voters Alliance.
Poll Watcher Describes Pennsylvania
Election Irregularities, Including 47
Missing USB Cards 2 replies
A Republican poll observer from Pennsylvania's Delaware County, told a Senate GOP Policy Committee hearing in Gettysburg on Wednesday, that he witnessed a range of Election Day irregularities, including 47 USB cards that went missing. Greg Stenstrom, who, besides being a poll watcher, said he is an expert in security fraud, told the hearing that he witnessed a number of chain-of-custody violations, including around mail-in ballots, the balance of votes from drop boxes, and the handling of USB card flash drives—all of which he said broke rules defined by the Delaware County Board of Elections and the election process review. "They didn't follow one," Stenstrom said. "It shocked me that this could
Multilateral Dreamin' 4 replies
American Greatness, by Angelo Codevilla Original Article
Posted by earlybird — 11/26/2020 12:41:11 PM Post Reply
The prospective renewal of the establishment's full powers in a Democratic administration secures its longtime foreign policy personnel's influence; yet it also puts them in the position of trying to convince Americans that they would use that influence to accomplish something other than the diminution of American security that they delivered to us over the past generation. Unable to argue that the same actions and attitudes would produce different results, they mix generalities about multilateralism with straw-man characterizations of those who understand that foreign governments pursue their proclivities—not their private dreams. They have another problem. The American people strongly approve of President Trump's emphasis on an "America First" foreign policy, and
Updated: Very Brief Election Challenge
Update 2 replies
Meaning In History, by Mark Wauck Original Article
I made the decision that I wouldn't attempt to track all the details of the ongoing election challenges. (Snip) the election laws in each state are unique to that state--and that's especially the case with regard to precisely those provisions that cover the types of voting most susceptible to fraud: absentee and mail in voting. It's impossible for me to keep up with the developments in a truly informed way. However, there have been some positive developments that offer hope for the Trump challenges. Note that not all of these challenges are being conducted by the Trump campaign organization. Some involve the local GOP and some involve private groups or
The New SCOTUS 10 replies
I still haven't read the Powell complaint. The reason is because I've been trying to get a handle on the SCOTUS issuance of injunctive relief against Cuomo's draconian and targeted restrictions on the Free Exercise of Religion in New York. This is a big story. Part of the story is that the Court was evenly divided on the First Amendment issues after Ginsburg's death--with Roberts siding with the liberals against the First Amendment (I say that with a purpose). That had resulted in decisions that left anti religious freedom decisions in place in California, because of the 4-4 split. There's no split any longer with Justice Amy on the Court,
Sidney Powell Files Lawsuit in Georgia
Alleging 'Massive Election Fraud' 10 replies
Epoch Times, by Mimi Nguyen Li Original Article
Attorney Sidney Powell filed a federal lawsuit late Wednesday alleging "massive election fraud" and multiple violations of the Constitution and Georgia's state laws in the 2020 general election, as well as issues pertaining to Dominion Voting Systems. The civil action alleges that the purpose of the scheme was for "illegally and fraudulently manipulating the vote count to make certain the election of Joe Biden as president of the United States." A similar separate suit was filed in Michigan. The Georgia suit (pdf) was filed in the U.S. District Court Northern District of Georgia Atlanta Division against Georgia Gov. Brian Kemp, Secretary of State Brad Raffensperger, and other election officials.
Some Milwaukee Neighborhoods Reported
Unusually High Election Turnout 10 replies
Epoch Times, by Petr Svab Original Article
Posted by earlybird — 11/26/2020 9:55:21 AM Post Reply
Some 13,000 fewer people voted in Milwaukee in the 2020 election, compared to 2016. But in several neighborhoods, the number of ballots cast dramatically increased. In one city ward, more than 105 percent of the eligible voting population cast ballots, based on demographic data from 2010—the most recent the city makes available. Another four wards had turnout over 92 percent.(Snip) Milwaukee, a city of nearly 600,000, is divided into more than 300 wards, each reporting election results for its residents. Ward 235 recorded 1,768 votes of which 1,391 were for Biden and 339 for Trump. But the ward only had a voting-eligible population of 1,680, according to the Milwaukee
Over Lin Wood's Election Lawsuit in Georgia 3 replies
Legal group files lawsuit challenging more
than 200,000 ballots in Georgia 8 replies
Just the News, by Daniel Payne Original Article
A conservative legal group filed a lawsuit Wednesday arguing that more than 200,000 votes in Georgia may have been either illegally counted or improperly uncounted, a number that dwarfs the current lead Joe Biden enjoys over President Trump in the state's official tally. The Thomas More Society's Amistad Project announced its latest battleground state litigation, claiming government data indicates that "well over 100,000 illegal votes [in Georgia] were improperly counted, while tens of thousands of legal votes were not counted." (Snip) alleged that "systematic failures by state and local election officials" were facilitated by "private monies donated by Facebook founder Mark Zuckerberg through a leftist organization called the Center for


text:
Q: Layout ocupando toda a tela Estou trabalhando em um projeto onde tenho uma tela que contém alguns elementos separados por tipos de layout diferentes. Todos esses elementos precisaram ser agrupados dentro de um único LinearLayout para que eu pudesse "envelopá-los" em um ScrollView. O problema é que um desses layouts está simplesmente 'jogando' para fora de vista outro, ocupando todo o espaço disponível. O resultado é esse:

Perceba na parte em azul que tem um layout (no caso, um RelativeLayout) esmagado para fora da tela. Esse layout deveria estar fixo na parte de baixo da tela, porém se eu mudar o tipo do preenchimento do LinearLayout imediatamente acima dele, esse é o resultado:

Os botões CANCELAR e SALVAR deveriam ficar fixos na parte de baixo da tela. Esse é o XML usado no layout:
<?xml version="1.0" encoding="utf-8"?>
<ScrollView xmlns:android="http://schemas.android.com/apk/res/android"
    xmlns:app="http://schemas.android.com/apk/res-auto"
    xmlns:tools="http://schemas.android.com/tools"
    android:id="@+id/content_new_color"
    android:layout_width="fill_parent"
    android:layout_height="fill_parent"
    android:clipToPadding="false"
    android:fillViewport="true"
    android:scrollbarStyle="insideOverlay"
    app:layout_behavior="@string/appbar_scrolling_view_behavior"
    tools:context="com.ions.colorcodes.activities.NewColorActivity"
    tools:showIn="@layout/activity_new_color">

    <LinearLayout
        android:layout_width="match_parent"
        android:layout_height="match_parent"
        android:orientation="vertical">

        <LinearLayout
            android:layout_width="match_parent"
            android:layout_height="wrap_content"
            android:orientation="vertical"
            android:paddingBottom="@dimen/activity_vertical_margin"
            android:paddingLeft="@dimen/activity_horizontal_margin"
            android:paddingRight="@dimen/activity_horizontal_margin"
            android:paddingTop="@dimen/activity_vertical_margin">

            <android.support.design.widget.TextInputLayout
                android:id="@+id/input_layout_name"
                android:layout_width="match_parent"
                android:layout_height="wrap_content">

                <EditText
                    android:id="@+id/input_color_name"
                    android:layout_width="match_parent"
                    android:layout_height="wrap_content"
                    android:hint="@string/hint_color_name" />

            </android.support.design.widget.TextInputLayout>

            <android.support.design.widget.TextInputLayout
                android:id="@+id/input_layout_code"
                android:layout_width="match_parent"
                android:layout_height="wrap_content">

                <EditText
                    android:id="@+id/input_color_code"
                    android:layout_width="match_parent"
                    android:layout_height="wrap_content"
                    android:hint="@string/hint_color_code" />

            </android.support.design.widget.TextInputLayout>

            <android.support.v4.widget.Space
                android:layout_width="match_parent"
                android:layout_height="16dp" />

            <TextView
                android:id="@+id/info_preview"
                android:layout_width="match_parent"
                android:layout_height="wrap_content"
                android:text="@string/info_preview" />

            <android.support.v4.widget.Space
                android:layout_width="match_parent"
                android:layout_height="8dp" />

            <LinearLayout
                android:id="@+id/card_preview_wrapper"
                android:layout_width="match_parent"
                android:layout_height="wrap_content"
                android:orientation="vertical"
                android:weightSum="1">

                <android.support.v7.widget.CardView
                    android:id="@+id/card_preview"
                    android:layout_width="160dp"
                    android:layout_height="wrap_content"
                    android:layout_gravity="center"
                    android:layout_margin="@dimen/card_margin"
                    android:elevation="4dp"
                    app:cardCornerRadius="@dimen/card_album_radius">

                    <RelativeLayout
                        android:id="@+id/preview_card"
                        android:layout_width="match_parent"
                        android:layout_height="match_parent">

                        <TextView
                            android:id="@+id/new_color_name"
                            android:layout_width="match_parent"
                            android:layout_height="wrap_content"
                            android:layout_alignParentStart="true"
                            android:layout_below="@+id/new_color_preview"
                            android:paddingLeft="@dimen/album_title_padding"
                            android:paddingRight="@dimen/album_title_padding"
                            android:paddingTop="@dimen/album_title_padding"
                            android:textStyle="bold" />

                        <TextView
                            android:id="@+id/new_color_hex_code"
                            android:layout_width="match_parent"
                            android:layout_height="wrap_content"
                            android:layout_alignParentStart="true"
                            android:layout_below="@+id/new_color_name"
                            android:paddingBottom="@dimen/songs_count_padding_bottom"
                            android:paddingLeft="@dimen/album_title_padding"
                            android:paddingRight="@dimen/album_title_padding" />

                        <ImageView
                            android:id="@+id/new_color_preview"
                            android:layout_width="match_parent"
                            android:layout_height="128dp"
                            android:layout_alignParentStart="true"
                            android:layout_alignParentTop="true"
                            android:background="#ffffff"
                            android:clickable="true"
                            android:scaleType="fitXY" />

                    </RelativeLayout>
                </android.support.v7.widget.CardView>
            </LinearLayout>
        </LinearLayout>

        <RelativeLayout
            android:id="@+id/preview_button_bar"
            android:layout_width="match_parent"
            android:layout_height="wrap_content">

            <LinearLayout
                android:layout_width="match_parent"
                android:layout_height="wrap_content"
                android:gravity="bottom"
                android:orientation="horizontal">

                <Button
                    android:id="@+id/btn_cancel_new_color"
                    style="@style/Widget.AppCompat.Button.Borderless"
                    android:layout_width="wrap_content"
                    android:layout_height="wrap_content"
                    android:layout_weight="1"
                    android:text="@string/btn_cancel" />

                <Button
                    android:id="@+id/btn_save_new_color"
                    style="@style/Widget.AppCompat.Button.Borderless.Colored"
                    android:layout_width="wrap_content"
                    android:layout_height="wrap_content"
                    android:layout_weight="1"
                    android:text="@string/btn_save" />
            </LinearLayout>
        </RelativeLayout>
    </LinearLayout>
</ScrollView>

Onde eu estou errando? Estou procurando soluções por um bom tempo e não consigo encontrar nada que me ajude.

A: Tente deixar o layout dos buttons fora do ScrollView +- assim:
    <?xml version="1.0" encoding="utf-8"?>
    <LinearLayout xmlns:android="http://schemas.android.com/apk/res/android"
        xmlns:tools="http://schemas.android.com/tools"
        xmlns:app="http://schemas.android.com/apk/res-auto"
        android:layout_width="match_parent"
        android:layout_height="match_parent"
        android:paddingLeft="@dimen/activity_horizontal_margin"
        android:paddingRight="@dimen/activity_horizontal_margin"
        android:paddingTop="@dimen/activity_vertical_margin"
        android:paddingBottom="@dimen/activity_vertical_margin"
        app:layout_behavior="@string/appbar_scrolling_view_behavior"
        tools:showIn="@layout/activity_segunda"
        tools:context="br.myapplication.SegundaActivity"
        android:orientation="vertical"
        android:weightSum="1">

<ScrollView
    android:layout_width="match_parent"
    android:layout_height="416dp"
    android:id="@+id/scrollView">

    <LinearLayout
        android:layout_width="match_parent"
        android:layout_height="match_parent"
        android:orientation="vertical"
        android:paddingBottom="@dimen/activity_vertical_margin"
        android:paddingLeft="@dimen/activity_horizontal_margin"
        android:paddingRight="@dimen/activity_horizontal_margin"
        android:paddingTop="@dimen/activity_vertical_margin">

        <android.support.design.widget.TextInputLayout
            android:id="@+id/input_layout_name"
            android:layout_width="match_parent"
            android:layout_height="wrap_content">

            <EditText
                android:id="@+id/input_color_name"
                android:layout_width="match_parent"
                android:layout_height="wrap_content"
                android:hint="Nome da Cor" />

        </android.support.design.widget.TextInputLayout>

        <android.support.design.widget.TextInputLayout
            android:id="@+id/input_layout_code"
            android:layout_width="match_parent"
            android:layout_height="wrap_content">

            <EditText
                android:id="@+id/input_color_code"
                android:layout_width="match_parent"
                android:layout_height="wrap_content"
                android:hint="Código da Cor" />

        </android.support.design.widget.TextInputLayout>

        <android.support.v4.widget.Space
            android:layout_width="match_parent"
            android:layout_height="16dp" />

        <TextView
            android:id="@+id/info_preview"
            android:layout_width="match_parent"
            android:layout_height="wrap_content"
            android:text="Preview" />

        <android.support.v4.widget.Space
            android:layout_width="match_parent"
            android:layout_height="8dp" />

        <RelativeLayout
            android:id="@+id/card_preview_wrapper"
            android:layout_width="match_parent"
            android:layout_height="wrap_content"
            android:orientation="vertical"
            android:weightSum="1">

            <android.support.v7.widget.CardView
                android:id="@+id/card_preview"
                android:layout_width="160dp"
                android:layout_height="wrap_content"
                android:layout_gravity="center"
                android:elevation="4dp"
                app:cardCornerRadius="5dp"
                android:layout_centerHorizontal="true">

                <RelativeLayout
                    android:id="@+id/preview_card"
                    android:layout_width="match_parent"
                    android:layout_height="match_parent">

                    <TextView
                        android:id="@+id/new_color_name"
                        android:layout_width="match_parent"
                        android:layout_height="wrap_content"
                        android:layout_alignParentStart="true"
                        android:layout_below="@+id/new_color_preview"
                        android:paddingLeft="10dp"
                        android:paddingRight="10dp"
                        android:paddingTop="10dp"
                        android:textStyle="bold" />

                    <TextView
                        android:id="@+id/new_color_hex_code"
                        android:layout_width="match_parent"
                        android:layout_height="wrap_content"
                        android:layout_alignParentStart="true"
                        android:layout_below="@+id/new_color_name"
                        android:paddingBottom="10dp"
                        android:paddingLeft="10dp"
                        android:paddingRight="10dp" />

                    <ImageView
                        android:id="@+id/new_color_preview"
                        android:layout_width="match_parent"
                        android:layout_height="128dp"
                        android:layout_alignParentStart="true"
                        android:layout_alignParentTop="true"
                        android:background="#ffffff"
                        android:clickable="true"
                        android:scaleType="fitXY" />

                </RelativeLayout>
            </android.support.v7.widget.CardView>
        </RelativeLayout>
    </LinearLayout>
</ScrollView>

<LinearLayout
   android:layout_width="match_parent"
   android:layout_height="0dp"
   android:orientation="horizontal"
   android:layout_weight="0.51">
    <Button
        android:id="@+id/btn_cancel_new_color"
        style="@style/Widget.AppCompat.Button.Borderless"
        android:layout_width="wrap_content"
        android:layout_height="wrap_content"
        android:layout_weight="1"
        android:text="@string/btn_cancel" />

    <Button
        android:id="@+id/btn_save_new_color"
        style="@style/Widget.AppCompat.Button.Borderless.Colored"
        android:layout_width="wrap_content"
        android:layout_height="wrap_content"
        android:layout_weight="1"
        android:text="@string/btn_save" />
</LinearLayout>
</LinearLayout>

A: Segundo o que eu percebi, você quer colocar os botões fixos no fundo do ecrã e a scrollview preencher o espaço restante.
Para tal pode fazer do seguinte modo
<?xml version="1.0" encoding="utf-8"?>
<LinearLayout xmlns:android="http://schemas.android.com/apk/res/android"
    xmlns:app="http://schemas.android.com/apk/res-auto"
    xmlns:tools="http://schemas.android.com/tools"
    android:layout_width="match_parent"
    android:layout_height="match_parent"
    android:orientation="vertical">

    <ScrollView
        android:id="@+id/content_new_color"
        android:layout_width="match_parent"
        android:layout_height="0dp"
        android:layout_weight="1"
        android:clipToPadding="false"
        android:fillViewport="true"
        android:scrollbarStyle="insideOverlay"
        app:layout_behavior="@string/appbar_scrolling_view_behavior"
        tools:context="com.ions.colorcodes.activities.NewColorActivity"
        tools:showIn="@layout/activity_new_color">

        <LinearLayout
            android:layout_width="match_parent"
            android:layout_height="match_parent"
            android:orientation="vertical">

            <LinearLayout
                android:layout_width="match_parent"
                android:layout_height="wrap_content"
                android:orientation="vertical"
                android:paddingBottom="@dimen/activity_vertical_margin"
                android:paddingLeft="@dimen/activity_horizontal_margin"
                android:paddingRight="@dimen/activity_horizontal_margin"
                android:paddingTop="@dimen/activity_vertical_margin">

                <android.support.design.widget.TextInputLayout
                    android:id="@+id/input_layout_name"
                    android:layout_width="match_parent"
                    android:layout_height="wrap_content">

                    <EditText
                        android:id="@+id/input_color_name"
                        android:layout_width="match_parent"
                        android:layout_height="wrap_content"
                        android:hint="@string/hint_color_name" />

                </android.support.design.widget.TextInputLayout>

                <android.support.design.widget.TextInputLayout
                    android:id="@+id/input_layout_code"
                    android:layout_width="match_parent"
                    android:layout_height="wrap_content">

                    <EditText
                        android:id="@+id/input_color_code"
                        android:layout_width="match_parent"
                        android:layout_height="wrap_content"
                        android:hint="@string/hint_color_code" />

                </android.support.design.widget.TextInputLayout>

                <android.support.v4.widget.Space
                    android:layout_width="match_parent"
                    android:layout_height="16dp" />

                <TextView
                    android:id="@+id/info_preview"
                    android:layout_width="match_parent"
                    android:layout_height="wrap_content"
                    android:text="@string/info_preview" />

                <android.support.v4.widget.Space
                    android:layout_width="match_parent"
                    android:layout_height="8dp" />

                <LinearLayout
                    android:id="@+id/card_preview_wrapper"
                    android:layout_width="match_parent"
                    android:layout_height="wrap_content"
                    android:orientation="vertical"
                    android:weightSum="1">

                    <android.support.v7.widget.CardView
                        android:id="@+id/card_preview"
                        android:layout_width="160dp"
                        android:layout_height="wrap_content"
                        android:layout_gravity="center"
                        android:layout_margin="@dimen/card_margin"
                        android:elevation="4dp"
                        app:cardCornerRadius="@dimen/card_album_radius">

                        <RelativeLayout
                            android:id="@+id/preview_card"
                            android:layout_width="match_parent"
                            android:layout_height="match_parent">

                            <TextView
                                android:id="@+id/new_color_name"
                                android:layout_width="match_parent"
                                android:layout_height="wrap_content"
                                android:layout_alignParentStart="true"
                                android:layout_below="@+id/new_color_preview"
                                android:paddingLeft="@dimen/album_title_padding"
                                android:paddingRight="@dimen/album_title_padding"
                                android:paddingTop="@dimen/album_title_padding"
                                android:textStyle="bold" />

                            <TextView
                                android:id="@+id/new_color_hex_code"
                                android:layout_width="match_parent"
                                android:layout_height="wrap_content"
                                android:layout_alignParentStart="true"
                                android:layout_below="@+id/new_color_name"
                                android:paddingBottom="@dimen/songs_count_padding_bottom"
                                android:paddingLeft="@dimen/album_title_padding"
                                android:paddingRight="@dimen/album_title_padding" />

                            <ImageView
                                android:id="@+id/new_color_preview"
                                android:layout_width="match_parent"
                                android:layout_height="128dp"
                                android:layout_alignParentStart="true"
                                android:layout_alignParentTop="true"
                                android:background="#ffffff"
                                android:clickable="true"
                                android:scaleType="fitXY" />

                        </RelativeLayout>
                    </android.support.v7.widget.CardView>
                </LinearLayout>
            </LinearLayout>

        </LinearLayout>
    </ScrollView>

    <RelativeLayout
        android:id="@+id/preview_button_bar"
        android:layout_width="match_parent"
        android:layout_height="wrap_content">

        <LinearLayout
            android:layout_width="match_parent"
            android:layout_height="wrap_content"
            android:gravity="bottom"
            android:orientation="horizontal">

            <Button
                android:id="@+id/btn_cancel_new_color"
                style="@style/Widget.AppCompat.Button.Borderless"
                android:layout_width="wrap_content"
                android:layout_height="wrap_content"
                android:layout_weight="1"
                android:text="@string/btn_cancel" />

            <Button
                android:id="@+id/btn_save_new_color"
                style="@style/Widget.AppCompat.Button.Borderless.Colored"
                android:layout_width="wrap_content"
                android:layout_height="wrap_content"
                android:layout_weight="1"
                android:text="@string/btn_save" />
        </LinearLayout>
    </RelativeLayout>
</LinearLayout>

redpajama_set_name: RedPajamaStackExchange


text:
Topical Collections
August 2021 - Volume 53 - Issue 8S
Thought you might appreciate this item(s) I saw at Medicine & Science in Sports & Exercise.
EP-11 Athlete Care and Clinical Medicine
Predictors Of Relief Following Botulinum Injection For Thoracic Outlet Syndrome
Miller Olson, Emily K.; Dyrek, Paige; Fereydooni, Arash; Harris, Taylor Christine; Lee, Jason T.; Kussman, Andrea; Roh, Eugene Y.
Stanford University, Palo Alto, CA. (Sponsor: Michael Fredericson, FACSM)
Medicine & Science in Sports & Exercise: August 2021 - Volume 53 - Issue 8S - p 377
doi: 10.1249/01.mss.0000763644.05744.0a
PURPOSE: Given the challenges of diagnosing neurogenic thoracic outlet syndrome (nTOS), both anesthetic blocks and botulinum toxin injections (BTIs) have been used to assist in the diagnostic algorithm for nTOS prior to surgical intervention. However, data has been mixed as to the benefit of BTI as a therapeutic option. We investigated predictors of relief following BTI.
METHODS: Patients diagnosed with nTOS who received a BTI at a single institution were retrospectively reviewed. Patient demographics, QuickDASH scores, and outcome following injection were collected from all charts.
RESULTS: 77 patients, including 30 males and 47 females, with a mean age of 31.4 +/- 12.3 received a BTI between 2000 and 2020. 60 patients (77.8%) experienced relief after the injection, of whom 32 (41.5%) reported significant (>60%) relief. 11 patients had no relief, and 6 were missing data. Initial QuickDash score (higher), gender (female), race (non-white), history of prior shoulder injury, and having at least one positive physical examination finding for TOS were included in the multivariate analysis. Female gender (OR 6.6, p = 0.049) and a positive physical exam finding (OR 9.0, p = 0.030) were both correlated with greater likelihood of relief following BTI. In regards to which patients had significant relief after BTI (vs mild or moderate), younger age (p = 0.008) and shorter symptom duration (p = 0.027) were found to be statistically significant predictors on univariate analysis.
CONCLUSION: Over three quarters of patients experienced relief after BTI, with 41.5% noting significant relief. Younger patients and those with shorter symptom duration prior to BTI were more likely to have the most benefit. Patients who did not have any positive physical examination findings for TOS may have been less likely to have a true diagnosis of nTOS, which could explain why these patients were less likely to experience relief after BTI. For many patients, particularly athletes who are trying to complete a competitive season, BTI may be an effective therapeutic treatment option. Understanding predictors of relief after BTI may help inform treatment algorithms for patients with nTOS.
Copyright © 2021 by the American College of Sports Medicine
View full article text
Predictors Of Relief Following Botulinum Injection For Thoracic Outlet Syndrome: 1164
Medicine & Science in Sports & Exercise53(8S):377, August 2021.
Articles in PubMed by Emily K. Miller Olson
Articles in Google Scholar by Emily K. Miller Olson
Other articles in this journal by Emily K. Miller Olson
twitter.com/MSSEonline
by the American College of Sports Medicine


and thank you for all your support and friendship during this past year.
I have decided to close this blog on the last day of 2008. I have a couple more things to share with you so will hopefully post a few more times.
I would also like to do a final giveaway, so if you would like to be entered into the draw please leave a comment before the 30th December sharing with us the funniest Christmas present you have ever received .
I hope that you all have a wonderful and peaceful holiday with those you love.
...and for the future who knows?
lots of love to you all....i am now off to wrap presents and hope i get them labelled correctly as i have had a few glasses!
Oh .. well .. I am not sure if you are leaving us for good Ginny.. I do hope not. I for one will miss your inspirational and hugely enjoyable blog.
Well funniest present you say.. not sure about funniest but most unexpected was a floor mop.. I still to this day don't know if it was a joke.
Every year my beloved man gives me some lingerie and every year I queue up in at the customer services desk at M & S to explain that my 36DD bra is more wishful thinking on my beloved's part and please could I exchange it for a 36B!
Wishing you and your family a wonderful Christmas Ginny..
ahhhhh... that's a shame? Do you have to go??
Hope you have a good festive break too.
"Have a happy Christmas day"!
Nooooooooooo! You can't go! Are you still going to be blogging? I very much hope so. The Blogosphere wouldn't be the same without you.
wishing you a very merry Christmas and I'll miss you if you stop blogging.
Does that mean you are starting another blog?
I do hope we can keep in touch !
Sad news Ginny as I have really enjoyed your blog but understand that life carries you forward & things change but will miss your post & the inspiration they bring.
Hope that doesn't mean you'll be vanishing from blogging altogether, I'd miss you.
A dreadful pink and white nylon knitted hat was the worst present I ever got, a shame as it had obviously taken a while to knit.
I am sad that you are stopping this blog as I get so much pleasure from popping over. I will have to see you at Sweet Myrtle instead! The 'funniest' Christmas present I ever received was a frozen Turkey as a present from my boss on Christmas eve!!!
just popping by to wish you a wonderful holiday with your family. I am sorry that you are planning to shut the door of the Flour Loft but quite understand that you feel it is time to move on. Thank you for all the pleasure that I have had reading about your projects and your artistic collaboration with Alice.
I once got a pair of grey nylon tights when I was about 13 but Ben has to have had the best present of all - when he was around 15 he got a plastic soldiers helmet from Uncle Harry and Auntie Margaret (I think they got the labels mixed up). Perhaps thats why he opts out now! Oh and now I recall, the first year that Nick and I were together I thought the large box he presented me with was full of lovely goodies like lingerie, clothes or jewells and instead it contained a Wok???!!! Mind you, it has had a lot of use so maybe not really a crap present. Oh and this year, Mum and Dad gave nick a huge huge bag of kindling wood. Mmmm.
Hi Ginny, hope you've had a lovely couple of days, and you all enjoyed yesterday's entertainment and performances. I can't think of funny or dire presents I've received, but I do remember one year (early teens) giving my father a boxof slug pellets. Strangely he was quite pleased! Looking for ward to seeing you on tuesday.
My funniest present was a pack of foil- wrapped mini chocolate Santas,..except that when they were opened and the foil removed,they were actually chocolate Easter Bunnies. It gave us all a laugh,I can tell you!


Since 2004, ROADI has become a fast developing manufacturer and marketer of diagnostic equipment and instrument in the automotive aftermarket industry. Our products serve three categories: Code Readers, Diagnostic Scan Tools and Instrumentation.
R&D and engineering is the heart of ROADI. Our engineering department comprises a significant portion of our workforce, through continuous improvement and development of new product lines. We work directly with both vehicle manufacturers and automotive governing agencies keep updated on all technical and regulation requirement impacting the automotive market. This ensures ROADI products will meet or exceed customer expectations now and into the future. ROADI are designed with the customer in-mind, so they are easy-to-use and include simple, detailed instructions in multiple languages.
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