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Cosumnes River College is a public community college in Sacramento, California. It opened in 1970, taking its name from the Cosumnes River which flows just a few miles to the south. As of Spring 2017, enrollment was at 13,091 students at its main and satellite campus in Elk Grove, California. Folsom Lake College, a former satellite campus, attained independence in 2004.

History
The concept for Cosumnes River College was included in a Master Facility Need Study that was approved by the Board of Trustees of the Los Rios Community College District in February 1967. A campus site of  was obtained and construction proceeded on a library building, a science building, an automotive and technology complex, a women's physical education building, and a swimming pool. In the fall of 1970 the college opened with an initial enrollment of about 2,100.

The architect who designed the original buildings of the college is Nacht & Lewis Architects of Sacramento. They also designed the Learning Resource Center in 2005.

In September 1975, the Business/Social Science building was dedicated, which included computer laboratories. In the spring of 1989, the California state finals for the National Geography Bee were first held within the recital hall. They have been held there in April ever since. In fall of 1990, the cafeteria building was opened, with facilities for both staff and student dining, and also for the instructional food service program. The next phase of construction was in the summer of 1991, which added the College Center building with space for the Admissions/Records, Financial Aid, Business Services, Administration and the book store. In fall of 1995 a visual and performing arts complex was opened, completing the roster of facilities in the college's original plan.

A permanent Child Development Center was completed in March 2002, and in December 2003 staff moved into a new Southeast Office Complex.

In 2004, the Folsom Lake Center was accredited and renamed as Folsom Lake College, becoming the fourth community college under Los Rios Community College District.

In 2004, construction on the Operations and Public Safety (OPS) building was completed. The building houses a variety of support services and departments. This includes a Health Services office staffed by college nurses, the Operations Department offices (housing the offices for Custodial/Maintenance Services and for Facility Use Processing), a Mail and Printing Center, and a substation of the Los Rios Community College Police Department.

The two-story Learning Resource Center was dedicated in 2005 with classroom space, and special computer labs for English as a Second Language, Digital Media, Journalism, and a Math Center.  These buildings were funded in part from a voter-approved community college district bond, Measure A.

The college's plans also include construction of an Elk Grove Center in the southern part of Elk Grove, California, United States. The center site was dedicated with a ground breaking in 2011.  Construction also began in 2011 on the $18-million Winn Center for Construction and Architecture which will provide instructional space for Construction, Construction Management Technology, Pharmacy Technology, and Photography among other programs. The building was supported by a $1-million gift from Mike Winn and family.

In partnership with the Sacramento Regional Transit, (SACRT) construction the CRC/Regional Transit Parking Structure began in 2011. In 2015, the college received light rail service when the Blue Line was extended to terminate at a new station on Bruceville Road on the east side of the campus.

Campus
The college occupies a campus of  on the south side of Sacramento.

Organization and administration
The college is part of the Los Rios Community College District.

Student life
Cosumnes River College is home to The Connection, an award-winning biweekly newspaper. An opinion zine, The Voice, is also published on campus.

Cosumnes River College is also home to the environmental student organization 'Students for a Sustainable Future Club' or SSF Club.  Established in 2011, this group exists to promote sustainability and environmentalism through education, advocacy, and activism both on campus and in the community. This club is an official chapter of the California Student Sustainability Coalition as well as an affiliate of the Sierra Student Coalition.

Athletics
The college was a factor in area college sports from the very beginning.  It opened up the 1971 football season against reigning state champion College of the Redwoods and nearly pulled off an upset. That team was coached by Coit Conant.  During the short period of time that the school fielded a football team 1971-1978, it was the predominant area power in that sport.  The school has provided powerful teams in all other sports since the inception of the school winning several conference titles.

In 2006, the college became home to the now-defunct Sacramento Heatwave of the American Basketball Association (ABA). In 2012, The Cosumnes River Hawks Baseball team took home the school's first ever state championship. In 2012 and 2013, the college's Community Athletic Center hosted the California Community College Athletic Association state basketball Final Four and Championship tournament.

Major construction of new athletic fields on the north side of campus was completed in 2012-13, including two soccer fields, softball complex, baseball complex (renamed Conway Field), and complete remodeling of the shared-use football stadium with the addition of artificial turf.

Notable alumni

 Mike Diva - VFX artist and director
 Jermaine Dye - Major League outfielder for the Chicago White Sox and 2005 World Series MVP
 David Hernandez - Major League relief pitcher for the Arizona Diamondbacks and Baltimore Orioles

References

External links
 Official website

California Community Colleges
Educational institutions established in 1970
Schools accredited by the Western Association of Schools and Colleges
Universities and colleges in Sacramento County, California
1970 establishments in California


Howard Rehs of Rehs Galleries offers this comment on the Doha sale of Orientalist paintings. Which prompts some worthwhile debate.
Rehs points out that the Doha sale was no different from the Winter and Fall Orientalist sales. That is to say uneven with strong prices for some works and many that failed to find buyers. The market churn (recently purchased works placed back on the market at higher estimates) is especially strong in this field.
According to the posted results, of the 78 lots offered only 37 found buyers, leaving 41 unsold … that is a 52.56% BI rate — not a very strong showing. In addition, 50 were sold within the last 2 years and 29 of those were among the BIs.
The Doha sale offered Orientalist paintings to an Orientalist group of buyers … and those that found a work of interest bid. Great works will always find a buyer and the Ernst paintings were top notch examples … at least from the photos. The work that really shows how the overall market has done is the Fabio Fabbi — that sold in 2002 for $47,800 … 7 years late $320,500.


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Q: How to register an application to a uri scheme in Mac OS X Mac OS Applications can register for custom uri schemes through their Info.plist file by specifying CFBundleURLTypes. In order to add another uri scheme the Application bundle needs to be modified.
The question is: how do I add an additional uri scheme for an already installed application, without changing the Application itself. Bonus points if this can be done from the command line.

A: I personally use RCDefaultApp preference pane, which is free. I think it manages these CFBundleURLTypes (and more) for you.
It's point and click. I'd like to hear about a command-line option, too.

A: defaultapp is a simple command line tool that does this. You need to download and built it yourself though.
You can then use a command like defaultapp ftp Transmit to set Transmit as the default app for ftp.

A: You can use LinCastor (http://onflapp.wordpress.com/lincastor/) for that. Can associate an URL protocol scheme with an AppleScript, shell script or existing application.

redpajama_set_name: RedPajamaStackExchange


text:
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Become part of a talented and dynamic team committed to your growth, development, and success. As trusted advisors to some of the world's largest companies, we help our clients solve their most complex problems and achieve outstanding outcomes. At Ducker Carlisle, your work will be challenging and impactful — across the firm and around the globe.
The strength of our collective is what makes us unstoppable. We're looking for passionate, ambitious individuals to join our team. If you strive for excellence, are excited to make a difference, and are dedicated to delivering the highest service value to clients, explore a career path at Ducker Carlisle.
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redpajama_set_name: RedPajamaCommonCrawl


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Q: Get result from REG QUERY I run below script to get the Symantec Endpoint Protection version but I just want to achieve the version number only. What should be rectified ?
@echo off
setlocal enabledelayedexpansion

For /F "tokens=3 delims= " %%A in ('reg query "HKEY_LOCAL_MACHINE\SOFTWARE\Symantec\Symantec Endpoint Protection\currentversion\public-opstate" /v "DeployRunningVersion"') do echo %%A
PAUSE

A: I would use powershell as a one liner from my batch file.
I do it all the time for things that suck to get to from cmd.exe.
As in (out of one of my .bat files):
for /f %%a in ('powershell -Command "Get-Date -format yyyy_MM_dd__HH-mm-ss"') do ECHO %%a
Try this (because it works FOR SURE):
@echo off
SetLocal

for /f "delims=" %%a in ('powershell -Command "Get-ItemPropertyValue -Path 'HKCU:Control Panel\Colors\' -Name ActiveBorder"') do Set ActiveBorder=%%a
echo ActiveBordervalues are %ActiveBordervalues%

EndLocal

I don't use Symantec Endpoint Protection so I can't actually query your key, but if I did.. I would try something like...
@echo off
SetLocal

for /f "delims=" %%a in ('powershell -Command "Get-ItemPropertyValue -Path 'HKLM:SOFTWARE\Symantec\Symantec Endpoint Protection\currentversion\public-opstate' -Name DeployRunningVersion"') do Set DeployRunningVersion=%%a
echo DeployRunningVersion is %DeployRunningVersion%

EndLocal

If you need the individual 1.2.3.4, set your "tokens=4 delims=." and read %%a, %%b, %%c, and %%d
Yep, right there inline in your batch file. :)
If you try to use special queries that use batch no-no delims like | or inner quotes, you will need to mess with your query by escaping them. It can be a real PITA to figure out within the for loop (that needs 'command').
Good Luck!
I hope it works.


The primary duty of the Materials Manager position is to perform administrative work directly related to the business related to production, exercising discretion and independent judgment on matters of significance by assuring the timely flow of materials to manufacturing, creating work orders to support the production plan, identifying, prioritizing, and expediting materials shortages, and maintaining various reports in support of the production plan. Materials Manager will also be responsible for on time deliver (OTD) for the Business Unit.
The Materials Manager develops and supports the execution of a production schedule that ensures the business meets the highest standards of customer satisfaction for on time delivery and responsiveness while achieving its monthly production targets. Using both MRP and sales order backlog information, and input from the business unit leadership team, the Materials Manager exercises discretion and independent judgment on matters of significance, by making determinations about what work will be organized and released for production.
Reviews sales order backlog report for top level assembly and subassembly requirements and exercises discretion and independent judgment to determine if these orders are supported by on-hand component inventory.
Exercises discretion and independent judgment by releasing and controlling work orders to support the production plan based on materials availability.
Exercises discretion and independent judgment for releasing materials to branches while ensuring material needs for the Phoenix branch are still met.
Identifies materials shortages and updates the backlog report with part numbers and due dates.
Exercises discretion and independent judgment by identifying shortages and notifying procurement specialists regarding pending shortages.
Reviews MRP planned orders for assigned commodities and works with procurement specialist to ensure materials are available to support production plan.
Exercises discretion and independent judgment to make decisions regarding inventory levels and works directly with procurement specialist to meet inventory plan goals.
Analyzes MRP to determine the impact of future shortages – create " What if" analysis.
Exercises discretion and independent judgment when implementing management policies to resolve bill of material issues in a timely manner.
Establishes competency in understanding of the MRP system.
Working knowledge of ERP/MRP systems. Upper level college coursework related to supply chain systems can be substituted for direct ERP/MRP system knowledge.
This is a full-time position. Work hours are Monday through Friday and shift start times are determined by your department manager. Overtime will be required as needed.
Bachelor' s degree in Business preferred; Supply Chain Management highly preferred.


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Singapore Airlines to absorb regional wing SilkAir after upgrade
Singapore Airlines to absorb regional wing SilkAir after upgrade /node/1305021/business-economy
Singapore Airlines said it would stump up more than S$100 million on a cabin upgrade for SilkAir, including new "lie-flat seats" in business class and backseat in-flight entertainment in business and economy class. (Reuters)
SINGAPORE: Singapore Airlines said Friday it will absorb its struggling premium wing SilkAir following a multimillion-dollar upgrade as part of a reform drive to stay competitive.
The move comes after the firm, facing tough rivalry in the high-end market from other full-service airlines and in economy class from budget carriers, last year consolidated its low-cost units TigerAir and Scoot into a single entity in a streamlining exercise.
SIA said it would stump up more than S$100 million ($74.5 million) on a cabin upgrade for the wholly owned subsidiary, including new "lie-flat seats" in business class and backseat in-flight entertainment in business and economy class.
The overhaul is expected to start in 2020 and the merger will take place after a sufficient number of aircraft have had their cabins redesigned, the firm added.
Friday's announcement "is a significant development to provide more growth opportunities and prepare the group for an even stronger future," SIA chief executive Goh Choon Phong.
Last year it embarked on a three-year transformation program in a bid fend off competition and defend its reputation as one of the world's leading airlines.
SIA said Thursday the transformation has started to bear fruit, with group net profit climbing 148 percent to S$893 million in the year ended March 31.
But SilkAir, a full-fare carrier that flies largely to holiday spots across Asia, turned in the weakest performance in the group with operating profit tumbling 57 percent to S$43 million.
The merger "should have been done years ago because SilkAir has always been the weakest link within the SIA group," said Shukor Yusof, an analyst with aviation consultancy Endau Analytics.
Shukor noted that SilkAir was losing to the competition because, as a premium airline, it charges full fares while a host of regional budget carriers sell tickets to the same destinations at a cost a fraction of the cost.
"For SIA, the cost of running SilkAir is very expensive," he said.
"As a full-fare airline, flying to a niche resort destination is a very difficult market to make money from because the market these days is focused on carriers offering cheap fares. It's all about costs."
Topics: aviation Singapore Airlines SilkAir Singapore
Singapore Airlines reports highest profit in 7 years
Singapore Airlines set to splash the cash in bid to up seat count by a quarter


Save SAR 800 (20.01%) – Earn 305 Shukrans What is Shukran? Shukran is the Landmark Group's award-winning loyalty programme in the Middle East, which allows you to earn Shukrans when you shop any of our brands.
Tufted for extra comfort and a elegant look, this attractive three-seater sofa sports a classy touch. Featuring a durable and soft fabric, this cushioned piece has wooden legs that add strength to the piece. The wooden support below gives it more support and the carved short legs add to the beauty.


Lin-Manuel Miranda has turned Broadway into his personal playground.
If you haven't listened to the soundtrack of the Broadway hit Hamilton yet, well, all I can say is I told you so, so don't blame me.
But you may not know about Ham4Ham. There is a lottery for Hamilton tickets every night, and those whose names are drawn get tickets for $10. (Thus, a Hamilton for Hamilton). When Lin-Manuel Miranda, author and star of the show, noticed that people were lined all the way around the block for the Ham4Ham lottery, he began bringing cast members outside for brief improvised pre-show performances, so that those who were unlucky would not go away completely unrewarded.
Since the weather has become entirely intolerable, Miranda has moved Ham4Ham indoors, which has allowed him to bring in even more Broadway greats (and other celebrities) as guest stars. And it is incredible. Enjoy the above video, of the great Audra McDonald singing a song from Hamilton in her Tony-winning character of Billie Holiday. And then go to the YouTube channel, where you can see Elmo singing with George Washington and Miranda living his lifelong dream of participating in a Broadway production of Les Miserables.
There's no accounting for taste, but if you don't enjoy this then you probably have no soul.


Art Press Release from Australia. Published by Rebecca Gabrielle Cannon on Monday 21 February 2011.
Funny that it's a DVD called 'The Planet', that sends me back into the lands of region free firmware hacking and ripping software.
Specifically, it was Johan Söderberg, or one of his webmonkeys, who sent the Region 2 encoded disc all the way to Australia (region 4). The Planet is a made for TV environmental documentary, from 2006, but given the quality of his earlier film, Lucky People Centre International, and Soderberg's editing efforts in general, it seemed worth a shot. ( Sodeberg is also famous as the editor of that Iraq war related lip-synced love duet featuring Tony Blair and George W. Bush) Anyway, it had been a while since I'd bought a DVD. The disc goes in, and up pops the reminder of region encoding. Pushed by the motion picture industry so films can be released at different dates at different times, through different distributors, and only effectively managing to annoy people who have paid to watch a film. Way to drive people to piracy.
Include ripping the disc to your hard-drive, and removing the region code restrictions using Mac The Ripper. Takes time and space.
Handbrake will transcode your DVD into a playable movie file. Takes even more time, but less space.
Or – for the adventurous – the mac firmware can be upgraded / de-crippled using free software and instructions from http://forum.rpc1.org/ ( see the mac section ). Once your drive's firmware is changed to region-free, you'll also need Region X to select a region each time.
There, aren't you glad you bought the disc, rather than downloaded a version you could watch straight away?
Sound of Noise is a feature film that uses found objects onscreen as musical instruments, and is made by the musicians involved with '"Music for One Apartment and Six Drummers":http://vimeo.com/7939104 '. Also a Swedish enterprise, and released in Dec 2010.
Pogo from Perth, is developing a global collection / album / DVD by cutting new tracks to footage shot in various locations ( after funding travel there by kickstarter ).


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Working with IP&C
Patent Process
Proof of Principle grant
Education Seminar Series
ShowcaseJelena Djurkic2021-11-13T04:01:11+00:00
Save the Date: May 17, 2022
The SickKids Innovation Showcase is an annual event that celebrates the most advanced health and life sciences ideas from the labs of SickKids researchers. Attendees get unparalleled access to emerging therapeutic and diagnostic technologies with high potential for market disruption and impact.
See below for details on the 2021 SickKids Innovation Showcase
Jacki Jenuth, PhDPartner | Lumira Ventures
Jacki Jenuth, PhD
With over 20 years of life science, IT and business development executive-level experience, Jacki is a key member of the senior investment team sourcing, conducting diligence on, structuring deals terms for and working closely at the board level with portfolio companies. Jacki has a strong reputation for providing the focus, clarity and cohesion required to drive projects from efficient inception to effective completion. Jacki also directs all aspects of Lumira Ventures' information technology initiatives having developed a world class venture capital analytics platform.
Prior to joining Lumira Ventures, Jacki worked at Base4 and Open Text Inc. where she developed, sold, and provided support for enterprise content management solutions targeted to the biotechnology and pharmaceutical industry in North America and Europe.
Deborah Palestrant, PhD, MBAPartner, Head of 4:59 | 5AM Ventures
Deborah Palestrant, PhD, MBA
Deborah Palestrant, Ph.D., M.B.A joined 5AM Ventures in 2018 as Partner, Head of 4:59. Previously, Dr. Palestrant was Vice President of Corporate Development & Strategy at Relay Therapeutics, where she executed business strategy including alliances, partnerships, and other collaborations and led communications. She has over 15 years of life sciences industry experience including drug discovery, company creation, operations, business development, and strategy.Dr. Palestrant holds a Ph.D. in biochemistry and molecular biophysics from Columbia University, an M.B.A from Northeastern University, and was Damon Runyon Cancer Research Foundation Postdoctoral Fellow at The Scripps Research Institute. She is based in the Boston, MA office.
Allyson Tighe, MBACo-Founder and Investor | Amplitude Ventures
Allyson Tighe, MBA
Allyson Tighe is a Co-Founder and Investor at Amplitude Ventures, a capital catalyst for highly innovative companies at the point of value acceleration. Amplitude works with promising Canadian healthcare companies that share their vision of bringing ground-breaking technologies to patients with a focus on building world-class Canadian companies in precision medicine and next-generation medical devices. Previously, Allyson was an investor at the BDC Healthcare Fund where their team managed $270 million in capital with investments in the drug, devices, diagnostics and digital health sectors. Allyson holds a Bachelor in Science in Genetics and a Masters in Science in Physiology, both from Western University, and an MBA from the Richard Ivey School of Business.
Matthew ClanceyDirector, Corporate Development & Licensing | Labcorp
Matthew Clancey
Matthew Clancey is a Director of Corporate Development and Licensing at Labcorp. In this role, he is responsible for leading diligence efforts around new technologies and testing opportunities, as well as executing on Labcorp's partnership strategies. His team manages deal flow for both diagnostics and CRO segments at Labcorp.Prior to his current role, Matthew spent five years in Labcorp Research & Development, leading the development and evaluation of novel technologies.
Prior to LabCorp, Matthew received his B.S. in Genetics and Cell Biology and B.A. in English Literature from the University of Minnesota – Twin Cities.
Wouter Meuleman, PhD, MBAPartner | Illumina Ventures
Wouter Meuleman, PhD, MBA
Wouter is a Partner at Illumina Ventures, a life sciences VC firm in the San Francisco Bay Area, investing in tools, diagnostics and therapeutics companies with a particular emphasis on genomics. Prior to Illumina Ventures, he worked at Illumina, Inc. in various roles including R&D, Product Development, and Corporate Development.A physical chemist by training, he began his career in life sciences as a founding team member at the Oxford University spin-out Oxamer, co-founded by Prof. Sir Edwin Southern. Following the company's acquisition by Oxford Gene Technology, he continued working alongside Prof. Southern leading R&D programs in areas such as single cell gene expression analysis and novel applications for DNA microarrays.
He obtained his undergraduate and Master's degree in Chemistry from the University of Ghent, Belgium; a PhD in Chemical Engineering from the University of Newcastle, U.K; and an MBA from the University of Cambridge, U.K.
Shobha Parthasarathi, PhDVP, External Innovation & New Ventures | Xontogeny
Shobha Parthasarathi, PhD
Shobha joined Xontogeny as Vice President, External Innovation & New Ventures. Shobha brings a combination of 20+ years of research, business development, strategic partnerships, and venture investing experience to development of new medicines and emerging healthcare technologies. Her career highlights include portfolio financings that have led to FDA drug approvals/marketed products, company acquisitions and IPO.Prior to joining Xontogeny, she was Vice President, Strategic Alliances and Business Development at Harrington Discovery Institute, a unique international initiative created to translate scientific discoveries from academia to development of therapeutics.
Shobha obtained Ph.D. in Molecular Genetics and Microbiology from Rutgers University. She serves on advisory Boards of several academic institutions and life sciences accelerators.
A sneak peek of each of our highlighted technologies. Registered attendees will also receive our Showcase Pitch Book – a non-confidential brief for each of these technologies.
P. Lynne Howell, PhD
Senior Scientist, Molecular Medicine
Novel therapeutic compositions for degrading bacterial and fungal biofilms
Bacteria and fungal colonies produce a protective coating barrier called a biofilm, which makes it difficult for traditional antibiotics to penetrate the organisms. Dr. Lynne Howell is a Senior Scientist in the Molecular Medicine program at SickKids, and her team is focused on understanding how these biofilms are formed. In collaboration with the Sheppard lab at McGill University, they discovered a group of natural enzymes that break down biofilms to enhance the effectiveness of traditional antibiotics. These enzymes are easily manufactured, stable, and non-toxic, and can be used as anti-infectives for pulmonary diseases like cystic fibrosis and chronic obstructive pulmonary disease (COPD). In addition, the enzymes can prevent colonies from attaching to device surfaces such as catheters and implantable devices, decreasing the probability of infection. In vivo, these enzymes have increased the antibiotic effectiveness for wound infections, and their use to prevent biofilm formation on surfaces in vitro and in vivo are underway.
Roman Melnyk, PhD
A potent tumor-targeted RAS biotherapeutic for cancer
Dr. Roman Melnyk has brought his industry experience from Merck & Co. to his role as a Senior Scientist at SickKids. The Melnyk lab has developed a novel intracellular delivery platform that is capable of transporting a wide range of protein-based cargo into cells, including an enzyme that specifically cleaves RAS oncoproteins. Nearly one in every three human cancers are driven by mutational activation of one of the three RAS isoforms: KRAS, NRAS and HRAS. Despite being one of the most highly coveted target families in cancer biology for the past three decades, RAS has proven to be virtually undruggable. Dr. Melnyk and collaborators have developed a therapeutic that targets all oncogenic mutants and isoforms of Ras; the modular design of the platform allows for targeting specifically to receptors enriched on different tumors. In vivo work in animal models has demonstrated drug penetration into xenografts and inhibition of tumour growth, exemplifying a successful intracellular delivery platform and a novel therapy for several currently untreatable cancers
Christopher Pearson, PhD
Senior Scientist, Genetics & Genome Biology
Methods of treating trinucleotide repeat expansion diseases
Dr. Christopher Pearson is a Senior Scientist at SickKids with over 25 years of research in molecular genetics. The Pearson lab works on rare conditions that are caused by unnatural slips and loops in the DNA, such as Huntington's disease, ALS, and 40+ other neurodegenerative diseases. In affected patients, these loops expand in size as the patient ages and eventually this results in the onset of disease. The Pearson lab has discovered a small molecule that binds selectively to the loop preventing size increase, forming the basis for a therapeutic platform. In the lab, the research team was able to successfully reduce the repeat expansions in the brain of a Huntington's disease mouse model, as well as in cells extracted from tissues of individuals affected by Huntington's disease with no off-target effects.
Martin Post, PhD
Senior Scientist, Translational Medicine
Engineered human alveolar-like macrophages as a cell therapy for respiratory diseases
Currently, there are inadequate therapeutic options for major respiratory diseases caused by prolonged inflammation leading to tissue damage and infection. Regenerative medicine for lung diseases has largely focused on the lung tissue lining, but the lung immune system has often been overlooked in approaches to disease treatment. The most abundant cell population in the lung airways are the alveolar macrophages (AM), which are part of the innate immune system and play a critical role in inflammation clearance. Dr. Martin Post, a Senior Scientist in the Translational Medicine program at SickKids leads his research group with the focus on lung-related development. The Post team has generated human alveolar-like macrophages (hALMs) from stem cells as a cell therapy for lung diseases including respiratory syncytial virus (RSV) and bacterial infections due to cystic fibrosis, which may mitigate disease severity and progression. hALM introduction in rodent studies showed lung specificity and did not elicit an immune response. These engineered hALMs also have the ability to express various factors including IL-10 and provide a non-immunogenic method to replenish alveolar macrophage populations in individuals with compromised lung immune systems.
Diagnostics & Research Tools
Robert Hamilton, MD
Staff Cardiologist
Senior Associate Scientist, Translational Medicine
Highly sensitive diagnostic tests for the prevention of sudden cardiac death
Sudden Cardiac Death (SCD) causes more years of potential life lost than any other non-cancer disorder. The diagnosis of some SCD disorders, including Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) and Brugada Syndrome (BrS), is difficult and expensive using current clinical assessments, and after complete workup 2/3 of ARVC patients still go undiagnosed. Dr. Robert Hamilton, a clinician scientist at SickKids, led the team that identified and developed accurate but simple tests that detect more than 98% of ARVC and BrS cases to inform treatment and prevention of SCD. These blood/saliva-based tests detect autoantibodies with high sensitivity and specificity, offering an accurate, cost-effective, and accessible diagnostic solution to all demographics vulnerable to SCD.
Jason Maynes, PhD/MD
Chief, Anesthesia and Pain Medicine
Scientist, Molecular Medicine
MATCH: Machine learning algorithms for toxicity and cardiac health
Current drug discovery and animal models of cardiac function do not accurately predict cardiac activity or toxicity, resulting in the failure of 30% of drug candidates in development, market removal of 16% of approved drugs, and as a result, the loss of billions of drug development dollars. To identify cardiotoxic compounds earlier in the drug discovery continuum, Dr. Jason Maynes, the Director of Research for Anesthesia and Pain Medicine and a Staff Anesthesiologist at SickKids, has led a team in the development of a machine-learning based platform called MATCH. MATCH incorporates multiple gold-standard tests of cardiac function into a unified, predictive report, and has proven its utility in existing preclinical drug discovery programs to efficiently identify the cardiotoxicity profile of investigational drugs.
Adam Shlien, PhD
Associate Director, Translation Genetics
Department of Paediatric Laboratory Medicine
Uri Tabori, MD
Staff Physician, Haematology/Oncology
Senior Scientist, Genetics & Genome Biology
Machine learning-driven NGS-based diagnostic tests to optimize clinical response in oncology
Next-Generation Sequencing (NGS) is proving to be an invaluable asset in the fight against cancer. First-generation analysis of tumor mutational burden (TMB) through NGS has improved the utility of therapeutic agents such as immune checkpoint inhibitors (ICI) in certain tumor types. However, TMB fails to accurately identify the ideal target patient population in numerous other cancers. Further leveraging NGS, SickKids researchers, Dr. Adam Shlien, an Associate Director of Translation Genetics in the Department of Paediatric Laboratory Medicine at SickKids, and Dr. Uri Tabori, a paediatric oncologist and principal investigator at The Arthur and Sonia Labatt Brain Tumour Research Centre, have developed a next generation complex biomarker analysis based on tumor-specific transcriptional output, called RNAmp. Through analysis of 10,000 patient samples with their proprietary machine learning algorithm, tumors identified with increased transcriptional output were found to express more mutations, which is a hallmark for improved ICI response. From preliminary clinical testing on more than 100 patients, RNAmp is a better prognostic indicator of ICI response as compared to TMB. RNAmp, combined with other diagnostic tests, such as genomic hyper mutant analysis, MSI, SNV, MMRD and POLE signatures developed at SickKids, provides a company creation/investment opportunity with a unique position in the industry.
Ryan Yuen, PhD
Scientist, Genetics & Genome Biology
Assistant Professor, Department of Molecular Genetics, University of Toronto
Whole-genome detection and interpretation of repeat expansions in autism and related disorders
Advancements in genome analysis have greatly improved gene discovery and clinical diagnosis for many human diseases, with genome sequencing becoming the current standard. While genome-sequencing data has enabled the identification of all classes of genetic variation, there are still difficulties in resolving genetic changes in more complex disorders, such as autism spectrum disorder (ASD). Despite over 100 genetic factors identified as being associated with ASD, the underlying genetic cause of 80% of all ASD is still unknown. 6% of the human genome is comprised of tandem repetitive DNA, and certain repeats have been associated with ~40% of ASD cases. Dr. Ryan Yuen, a Scientist in Genetics & Genome Biology (GGB) at SickKids, and Dr. Stephen Scherer, a Senior Scientist in GGB and Director of The Centre for Applied Genomics at SickKids, have led their teams in determining the impact of tandem repeats on the genetic risk of developing ASD. They have developed a method to detect tandem repeats allowing identification of gene candidates involved in ASD, which can be applied to other complex genetic disorders. From an analysis of clinical data of more than 17,000 samples and controls, this method provides a more sensitive approach in capturing ASD diagnoses that would be otherwise missed using current standards.
Want to learn more about commercialization opportunities at SickKids? Contact us today.
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I'll be honest... one deciding factor for whether or not I could picture myself at a grad school depended on whether or not the college had a decent football team (and I honestly considered applying to Oregon solely for that reason).
While they aren't the Clemson Tigers, the UCLA Bruins are a cheer-worthy team (who were ranked highly at the beginning of the 2014 season...), and they play in the Rose Bowl Stadium - how cool is that?
Traffic wasn't too bad until Pasadena. We were sent circling through neighborhoods, trying to follow the route to parking. I think we looped all the way around the stadium first. Then when we finally arrived at the lot, it was full. So I ended up parking along a residential street, which worked out surprisingly well when we didn't have to pay $25 to park and also left the game to no traffic.
We just missed kick-off, so we really missed tailgating which was a bit of a bummer because it looked pretty extravagant... we'll be sure to get there further before kick-off next time!
Rather than carrying around my DSLR, I brought my Nikon 1 J1 Compact Camera with the 30-110mm lens which is lightweight and fits nicely in my purse.
Now, something that I'm learning now that I'm at UCLA is that I was really spoiled at Clemson. There are a lot of "extras" that are included in the (very reasonable in-state) price of tuition at Clemson that are not at UCLA. One of those "extras" is football tickets. At Clemson, tickets are free to all students on a first come, first serve basis. At UCLA, students must purchase tickets to football and basketball games. They encourage students to purchase the Den Pass which includes tickets to all home football and basketball games and is the only way to get a ticket for the USC football rivalry game. What I did not know is that at the beginning of the summer, they sent out emails offering the Den Pass at a very reasonable price of $66... but that price increases substantially over time. The cost of the same Den Pass now is $176!!!
Individual game tickets for students are typically $15. However, UCLA emailed us with a "new student free game" offer (probably to entice us to buy the Den Pass), so I was able to go to the Oregon game at no charge. So I guess they do include some things.
The student sections are huge, and students are seated on a first-come, first-serve basis. There are no pre-assigned seats. We were able to find seats in Section 8 which was the last section with seats (Sections 5-8 have individual seats). The other sections all had bleacher seating... which is what I'm used to at Clemson, anyway.
It was incredibly hot at the Rose Bowl (but it was nowhere near as miserable as the first Clemson home game versus SC State this year). They had distributed rally towels, and all of the students were using them as hats and soaking them to keep themselves cool.
The student section at Clemson is much more condensed... and I used to organize our camp-outs for tickets so that we always had a spot near the very front (and during the 2012 season, my friends and I spent every home game on the front row). So I'm not sure if it's because UCLA's student section was over twice as large, or if because I was sitting much further back, but I didn't feel that sense of community that I always experience at the Clemson games.... doing cheers together, jumping up and down and high-fiving strangers.
Of course, I also must keep in mind that UCLA was not performing very well. While we held up okay during the first half, Oregon completely destroyed us in the third quarter.
I love learning school's unique game traditions. UCLA rings a bell and puts three fingers in the air when the defense holds the opposing team to third down. Of course, I'm not sure how effective this ritual is because once when we were all holding three fingers in the air, Oregon scored a touchdown.
I wanted more cheers, though. Mostly, I wanted to yell, "Goooooo!" and point on first down. Jump up and down to Zombie Nation and sing "Woah oh oh oh oh oh oh," Shake my hand in the air on kick-off. Other than the three fingers on third down routine, I wasn't picking up on much tradition.
The band performed at halftime, and apparently they performed on the Amazing Race. The show involved competing against USC, and of course UCLA won. It's funny because both schools I've gone to, all of the students hate USC with a burning passion.
So of course I thought a lot about what to wear to the game. Friday night, I was thinking about going shopping for a game day dress.... and that's when I realized that UCLA girls might not wear game day dresses.
In the south, football is a social event, as well as a time to make a school-colored fashion statement. Girls wear dresses and guys wear polo shirts and button-ups... and the poor frat boys will even go to the games in blazers and sport coats. Game day attire is very important, and I have made shopping trips just to acquire more orange and purple to wear the next day.
At UCLA, this is not the case. The standard uniform here is a tank top or t-shirt with high-rise blue jean shorts. And some girls wore just sports bras... and there were several shirtless guys. Thankfully, the outfit I had come up with was a fitted UCLA t-shirt (that Dad bought me at open house) and a high-waisted blue jean circle skirt.
Once we started getting our asses handed to us, the student section cleared out.
So it sucked that we lost, but playing in the Rose Bowl stadium was pretty cool. And next time, I need to get there in time for Bruin Walk before the game.


We wanted a country cottage feel, warm, early spring feel, And everyone to feel relaxed and comfortable.
We did not feel that we would have been able to achieve the look we wanted with DIY and Heart Invites expert advice, flexibility with colours and design proved we were right.
We saw Heart Invites nomination in a wedding magazine, checked out the website and saw designs that were very unique and exactly what we wanted, and with the flexibly of changing colours and design made Heart Invites the perfect choice! The final products were perfect and we had some fantastic feedback from our guests!
Planning planning planning! Set yourself deadlines to achieve and book things and make sure you stick to them as much as you can because time runs away from you especially the closer you get to the big day!


A bill to reauthorize the National Oilheat Reliance Alliance Act of 2000, and for other purposes.
Congratulating the Surety and Fidelity Association of America on its 100th anniversary.
A resolution commemorating the 100th anniversary of the founding of the Greater Philadelphia Association of Realtors.
Recognizing the ongoing work of The United States Sweet Potato Council and expressing support for designation of a "Sweet Potato Month".
A resolution commending the Association for Advanced Life Underwriting on its 50th anniversary.
To provide temporary duty reductions for certain cotton fabrics, and for other purposes.


text:
Survey seeks academic snapshot
Survey to improve "educational experience"
karen herland
For the first time, Concordia will participate along with 600 other North American universities and colleges in the National Survey of Student Engagement (NSSE).
"This is a theoretically justifiable and valid way to measure university quality and performance," said Bradley Tucker, who is the senior analyst of academic planning in the Office of the Provost. This conceptual and statistical rigour is not necessarily found in many of the newspaper-commissioned polls and academic rankings published throughout the year.
The NSSE was established by a private trust in 1999 to provide participating institutions with an independent measure of student satisfaction with their academic experience.
The 20-minute online survey assesses student satisfaction in five areas: level of academic challenge, active and collaborative learning, student-faculty interactions, enriching educational experience and supportive campus environment.
The key to the success of the initiative is student participation. Tucker's office has used a series of criteria to find students "in all walks of life" who fall into two distinct categories: those finishing their first year at Concordia, and those with enough completed credits to graduate this year. Within each category, students have been selected to ensure that the faculties, campuses, and other characteristics of Concordia are adequately represented.
The NSSE offices will randomly select 2,500 students in each category next month. Each student will be asked to participate in the survey with an email invitation from President Lajeunesse.
Tucker is counting on an 80 per cent return rate to ensure accurate and useful results. The Concordia Student Union supports the project and has been working closely with Tucker to ensure the goal is met.
Each participating institution predetermines what information they want to examine through the survey's standardized questions. The initial numbers are crunched at Indiana University by the team that administrates the survey, and then the numbers are returned to the participating institutions for their own use.
"It's a treasure-trove of data that will help us understand how students view their academic experience. We intend to translate these data into real change." Tucker said.
The administration team also provides information on how best to use the results. The results can then be compared against benchmarks of all participating schools, similar institutions, nearby institutions or in any other way that will prove useful.
"Our academic plan is designed to move us forward; these results will help us measure our progress toward providing even better overall educational experiences for our students," said Martin Singer, Provost and Vice-President, Academic Affairs.
Nearly 1,000 institutions have participated in this survey since its inception. Tucker said it is not economically viable to participate year after year, because "institutional change is a process that requires patience."
However, the opinion of a cross-section of 4,000 to 5,000 students — on everything from whether they were able to do internships or lead classroom discussions, to how quickly they were able to get feedback from professors on assignments and whether the university offered non-academic support — should help set the course for that change.
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At only 28, Raquel Dispenziere may be one of Riverhead's youngest entrepreneurs, but her business savvy belies her years.
Dispenziere, owner of Gabriel Loren the Salon, has taught college classes on the business of salon management in California, where she lived for 10 years before moving back to Riverhead earlier this year.
Dispenziere opened the doors of her new shop on Howell Avenue for the first time this morning. Along with her father Mike, sister Chelsea and stepmother Susan Tocci, Dispenziere has been working to build, equip and decorate the 1,400-square-foot space for the past few months. The result is a sleek, modern space with eight work stations.
"I had so much help from my family. I could not have done this without them," Dispenziere said.
She already has three stylists at work — Kaitlyn Hernandez, Marielle Pugliese and Ashley Fogarty — and says several others will be joining the staff shortly.
Gabriel Loren the Salon — named for her young son Gabriel — features a Paul Mitchell color bar where customers can peruse the available options.
The salon will also offer facials and massage services in private rooms that are not yet furnished. She was concentrating on getting the salon itself in shape for opening day, Dispenziere explained.
Gabriel Loren the Salon will celebrate its grand opening on January 10 with a ribbon-cutting, special promotions and giveaways, Dispenziere said. The salon is located at 215 Howell Avenue, across from town hall. The freestanding building it occupies had been vacant for several years; it was last occupied by a laundromat.
More information about the grand opening will be posted to the salon's Facebook page.


Manifesto of Catherine the Great - 1763 List of Immigrants 1929/30 - "Harbiners"
Printed Resources - Harrison Co.
Printed Resources and Lookups - Scott Co.
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Archives for these and other wills and original records.
Greetings, News and Photo Updates!
GenRing - The LARGEST Genealogy Ring on the 'Net!
This page accessed times plus more than 2,289 that got rolled back and racked up on Edition I.


text:
Join PAC
PAC President's Letter to President Biden on Increased Russian Military Presence Near Ukrainian Border
President Joseph R. Biden, The White House, 1600 Pennsylvania Avenue NW, Washington, DC, 20500 More»
Oświadczenie Prezesa PAC na temat kryzysu na granicy Polski z Białorusią
Oświadczenie Prezesa Kongresu Polonii Amerykańskiej na temat kryzysu na granicy Polski z Białorusią. More»
The Official Statement of PAC NY Downstate Division re: Desecration of Father Jerzy Popieluszko Statue
"On May 3, 2021 the day commemorating the Polish Constitution, unknown vandals spray painted anti-Polish slogans on the statue; they drew a Nazi symbol of Hitler's mustache on the face, placed a plastic trash bag over its head and strew garbage around the statue..." More»
President Joseph R. Biden, The White House, 1600 Pennsylvania Avenue NW, Washington, DC, 20500
Oświadczenie Prezesa Kongresu Polonii Amerykańskiej na temat kryzysu na granicy Polski z Białorusią.
"On May 3, 2021 the day commemorating the Polish Constitution, unknown vandals spray painted anti-Polish slogans on the statue; they drew a Nazi symbol of Hitler's mustache on the face, placed a plastic trash bag over its head and strew garbage around the statue..."
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Today, the Polish American Congress is an "umbrella" organization – a federation of more than 3,000 Polish American organizations, clubs, and veterans' groups. The individual membership is organized into twenty-nine State Divisions and nine Chapters. In the aggregate, there are more than one million members of the PAC nationally. The organization maintains offices in Chicago and Washington, D.C.
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Promoting knowledge about Polish Americans and the Polish American community, its history, accomplishments and contributions.
Closely monitoring U.S. legislation and policies that could directly or indirectly affect Polish Americans, e.g. the inclusion of Poland in the Visa Waiver Program, section 245(i), H1-B Visas, the Diversity Visa Lottery, and Immigration Reform
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text:
Adeline is a feminine given name meaning 'noble' or 'nobility'. It is of German origin and derived from Old High German "adal" which means noble. It lives on in the Modern High German words Adel (nobility), edel (noble) adelig (noble). It is a related to Adèle. Adeline was introduced to England by the Normans in the 11th century and was very common in the Middle Ages. Its variants include Adelin, Adelina, Adaline, Adalyn, Adalynn, Adelyn, Adalene, Adeleine, Aada, Ada, Alina, Aline, Adelita and Alita, Zélie.

Notable people with the name include:

 Adeline Pond Adams (1859–1948), American writer and wife of Herbert Adams
 Adeline, Countess of Cardigan and Lancastre (1825–1915), wife of James Brudenell, 7th Earl of Cardigan
 Adeline André, French fashion designer and the head of one of the ten haute couture design houses in Paris
 Adeline Canac (born 1990), French pair skater, currently skating with Yannick Bonheur
 Adeline Genée DBE (1878–1970), Danish/British ballet dancer
 Adeline Geo-Karis (1918–2008), Republican politician and a member of the Illinois Senate for the 31st District
 Adeline Hazan (born 1956), French politician, MEP for the east of France, and mayor of Reims since March 2008
 Adeline Kerrar (1924–1995), infielder and catcher, played in the All-American Girls Professional Baseball League in 1944
 Adeline Knapp (1860–1909), American journalist, author, social activist, environmentalist and educator
 Adeline Masquelier (born 1960), Associate Professor of Anthropology at Tulane University in New Orleans, Louisiana
 Adeline McKinlay, American tennis player of the end of the 19th century
 Adeline Miller, alias Adeline Furman, American madam and prostitute
 Adeline Rittershaus (1876–1924), philologist, a scholar in old Scandinavian literature, and champion for the equality of women
 Frances Adeline "Fanny" Seward (1844–1866), daughter of United States Secretary of State William H. Seward
 Frances Adeline Seward (1805–1865), born in 1805, the daughter of Judge Elijah Miller and Hannah Foote Miller
 Louise Adeline Weitzel (1862–1934), German-American writer
 Adeline Dutton Train Whitney (1824–1906), American poet and writer of books for girls
 Adeline Virginia Woolf (1882–1941), British modernist author
 Adeline Wuillème (born 1975), French foil fencer who competed in three Olympic games
 Adeline Yen Mah, Chinese-American author and physician
 Lisa Adeline Mainiero, American writer and management professor

References

Feminine given names

redpajama_set_name: RedPajamaWikipedia


text:
Hutton Oil Field är ett oljefält i Storbritannien. Det ligger i den norra delen av landet,  km norr om huvudstaden London.

Terrängen runt Hutton Oil Field är varierad.  Det finns inga samhällen i närheten.

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The locally filmed television series "Swamp Thing" has found itself bogged down by some unexpected news.
The currently in-production project is being shut down earlier than expected as its producer, Warner Bros., evaluates the future of its DC Universe streaming service, on which the series was scheduled to premiere May 31, according to several sources within the local industry.
Local crew members were notified of the unexpected development Tuesday night, and were told the project would wrap production on episode 10 and then halt as writers and producers rewrite an ending. Initially, the show was scheduled to film 13 episodes through May.
I haven't really touched too much of their original content, mostly focusing on the comics and episodes of the Batman animated series, but this is a bummer if WB is already looking into pulling the plug.
I feel sorry for all the talent with this weight attached to their ankles.
That's a very pretty car.


text:
Q: Plotted function looks different from expected using matplotlib python I have defined a function and I expect its graph to look like the graph below:

However, when I try to plot it in Python using matplotlib it looks a little different from what is expected and I have not been able to figure out where it has gone wrong. I thought the reason may be operator precedence in Python, but I think I have included a superfluous number of brackets in so that it should not even matter.

The specific function I am using to plot it is as follows:
def f(x):
    return 50 * (1/(1 + ((50/5) -1 ) * e ** (-max(0, 0.1 * x))))

and the entire code is as follows:
import matplotlib.pyplot as plt
import numpy as np
from math import e

# 100 linearly spaced numbers between -10 and 100
N=200
x = np.linspace(-10,100,N)

def f(x):
    return 50 * (1/(1 + ((50/5) -1 ) * e ** (-max(0, 0.1 * x))))

f_eval = np.zeros(N)
for idx, i in enumerate(x):
    f_eval[idx] = f(i)

# setting the axes at the centre
fig = plt.figure()
ax = fig.add_subplot(1, 1, 1)
ax.spines['left'].set_position('center')
ax.spines['bottom'].set_position('zero')
ax.spines['right'].set_color('none')
ax.spines['top'].set_color('none')
ax.xaxis.set_ticks_position('bottom')
ax.yaxis.set_ticks_position('left')

# plot the function
plt.plot(x,f_eval, 'r')

# show the plot
plt.show()

Edit: nevermind - only after I had tried to figure this out for hours had and posted the question on here had I realised that the graph was right all along but the y-axis was just drawn differently.
The line that says:
ax.spines['bottom'].set_position('center')
should be changed to:
ax.spines['bottom'].set_position('zero')


text:
H-1B: Bills introduced in House, Senate to ax…
H-1B: Bills introduced in House, Senate to ax per-country green card limits
Bay Area politicians Lofgren, Harris part of bipartisan legislation push
MERCURY NEWS PHOTO BY MERI SIMON 7/18/2000 Asif Siddique goes through a pile of papers containing his visa and other immigration documents. He has been working in the U.S. on an H-1B visa but his visa expired before he was approved for a green card. He can no longer work in the U. S. but he stays here while he waits hoping to get his green card. Siddique has been in the US since 1987. He went to school at Ohio State University. He is originally from Pakistan.
By Ethan Baron |
PUBLISHED: February 7, 2019 at 5:57 pm | UPDATED: February 9, 2019 at 5:53 am
Members of the U.S. Senate and House of Representatives on Thursday introduced matching bills that would throw out per-country limits on employment-based green cards.
Current law caps the annual percentage of green card recipients from any one country at 7 percent.
That restriction hits Indian citizens hardest, because of the high numbers of Indians in the U.S. who are eligible for green cards. Indian citizens on the H-1B visa and other visas can wait years or even decades for a green card. Chinese citizens also face long delays.
The "Fairness for High-Skilled Immigrants Act" bills from the House and Senate would also adjust per-country limits for family-based green cards.
The House bill was introduced by Democrat Bay Area Congresswoman Zoe Lofgren and 113 other representatives, both Democrat and Republican. The Senate bill was introduced by Democrat California Sen. Kamala Harris and 14 other senators from both parties.
Sen. Mike Lee of Utah said in a press release that the Senate bill's supporters include Google, Walmart and the Information Technology Industry Council, which represents major Silicon Valley tech companies and also outsourcing firms that receive vast numbers of H-1B visas.
Lofgren said the U.S. immigration system has been broken for decades. "At the heart of this broken system are the outdated employment- and family-based immigration systems, which suffer under decades-long backlogs," Lofgren said in a statement. "In combination with the per-country limits, these backlogs keep nuclear families apart for decades, while preventing U.S. employers from accessing and retaining the employees they need to stay competitive."
John Miano, a lawyer for the Center for Immigration Studies, which pushes for reduced immigration to the U.S., said the proposed legislation, if passed, would bring about "the most massive change in the history in immigration policy" and create a "train wreck" in America's immigration system.
"The effect of the bill is to replace America's system of diversity immigration with an India-first system," Miano said in an email Friday. "Because India has monopolized the H-1B system, it would take over the employment-based green card system as well. The long-term effect is that about 75 percent to 80 percent of employment-based green cards would go to India."
Read about the big lottery change and get more H-1B visa coverage – Click here to read the stories
Ethan Baron
Bill to scrap per-country green card cap passes House with bipartisan support
Marin supervisors adopt new rules for 5G
Man shot by police amid alleged LSD rampage is YouTube engineer
Border Patrol probes agents who reportedly joked about dead migrants in private Facebook group


This article appeared in the June 2, 2008 edition of The Nation.
Paradoxically, the next few years under the new democratic dispensation saw the gutting of government investment capacity. As in Mexico the World Bank and IMF, working on behalf of international creditors, pressured the Corazon Aquino administration to make repayment of the $26 billion foreign debt a priority. Aquino acquiesced, though she was warned by the country's top economists that the "search for a recovery program that is consistent with a debt repayment schedule determined by our creditors is a futile one." Between 1986 and 1993 8 percent to 10 percent of GDP left the Philippines yearly in debt-service payments--roughly the same proportion as in Mexico. Interest payments as a percentage of expenditures rose from 7 percent in 1980 to 28 percent in 1994; capital expenditures plunged from 26 percent to 16 percent. In short, debt servicing became the national budgetary priority.
Spending on agriculture fell by more than half. The World Bank and its local acolytes were not worried, however, since one purpose of the belt-tightening was to get the private sector to energize the countryside. But agricultural capacity quickly eroded. Irrigation stagnated, and by the end of the 1990s only 17 percent of the Philippines' road network was paved, compared with 82 percent in Thailand and 75 percent in Malaysia. Crop yields were generally anemic, with the average rice yield way below those in China, Vietnam and Thailand, where governments actively promoted rural production. The post-Marcos agrarian reform program shriveled, deprived of funding for support services, which had been the key to successful reforms in Taiwan and South Korea. As in Mexico Filipino peasants were confronted with full-scale retreat of the state as provider of comprehensive support--a role they had come to depend on.
And the cutback in agricultural programs was followed by trade liberalization, with the Philippines' 1995 entry into the World Trade Organization having the same effect as Mexico's joining NAFTA. WTO membership required the Philippines to eliminate quotas on all agricultural imports except rice and allow a certain amount of each commodity to enter at low tariff rates. While the country was allowed to maintain a quota on rice imports, it nevertheless had to admit the equivalent of 1 to 4 percent of domestic consumption over the next ten years. In fact, because of gravely weakened production resulting from lack of state support, the government imported much more than that to make up for shortfalls. The massive imports depressed the price of rice, discouraging farmers and keeping growth in production at a rate far below that of the country's two top suppliers, Thailand and Vietnam.
The consequences of the Philippines' joining the WTO barreled through the rest of its agriculture like a super-typhoon. Swamped by cheap corn imports--much of it subsidized US grain--farmers reduced land devoted to corn from 3.1 million hectares in 1993 to 2.5 million in 2000. Massive importation of chicken parts nearly killed that industry, while surges in imports destabilized the poultry, hog and vegetable industries.
During the 1994 campaign to ratify WTO membership, government economists, coached by their World Bank handlers, promised that losses in corn and other traditional crops would be more than compensated for by the new export industry of "high-value-added" crops like cut flowers, asparagus and broccoli. Little of this materialized. Nor did many of the 500,000 agricultural jobs that were supposed to be created yearly by the magic of the market; instead, agricultural employment dropped from 11.2 million in 1994 to 10.8 million in 2001.
This is not simply the erosion of national food self-sufficiency or food security but what Africanist Deborah Bryceson of Oxford calls "de-peasantization"--the phasing out of a mode of production to make the countryside a more congenial site for intensive capital accumulation. This transformation is a traumatic one for hundreds of millions of people, since peasant production is not simply an economic activity. It is an ancient way of life, a culture, which is one reason displaced or marginalized peasants in India have taken to committing suicide. In the state of Andhra Pradesh, farmer suicides rose from 233 in 1998 to 2,600 in 2002; in Maharashtra, suicides more than tripled, from 1,083 in 1995 to 3,926 in 2005. One estimate is that some 150,000 Indian farmers have taken their lives. Collapse of prices from trade liberalization and loss of control over seeds to biotech firms is part of a comprehensive problem, says global justice activist Vandana Shiva: "Under globalization, the farmer is losing her/his social, cultural, economic identity as a producer. A farmer is now a 'consumer' of costly seeds and costly chemicals sold by powerful global corporations through powerful landlords and money lenders locally."
According to Oxfam, the number of sub-Saharan Africans living on less than a dollar a day almost doubled, to 313 million, between 1981 and 2001--46 percent of the whole continent. The role of structural adjustment in creating poverty was hard to deny. As the World Bank's chief economist for Africa admitted, "We did not think that the human costs of these programs could be so great, and the economic gains would be so slow in coming."
Malawi's defiance of the World Bank would probably have been an act of heroic but futile resistance a decade ago. The environment is different today, since structural adjustment has been discredited throughout Africa. Even some donor governments and NGOs that used to subscribe to it have distanced themselves from the Bank. Perhaps the motivation is to prevent their influence in the continent from being further eroded by association with a failed approach and unpopular institutions when Chinese aid is emerging as an alternative to World Bank, IMF and Western government aid programs.
Farmers' groups have networked internationally; one of the most dynamic to emerge is Via Campesina (Peasant's Path). Via not only seeks to get "WTO out of agriculture" and opposes the paradigm of a globalized capitalist industrial agriculture; it also proposes an alternative--food sovereignty. Food sovereignty means, first of all, the right of a country to determine its production and consumption of food and the exemption of agriculture from global trade regimes like that of the WTO. It also means consolidation of a smallholder-centered agriculture via protection of the domestic market from low-priced imports; remunerative prices for farmers and fisherfolk; abolition of all direct and indirect export subsidies; and the phasing out of domestic subsidies that promote unsustainable agriculture. Via's platform also calls for an end to the Trade Related Intellectual Property Rights regime, or TRIPs, which allows corporations to patent plant seeds; opposes agro-technology based on genetic engineering; and demands land reform. In contrast to an integrated global monoculture, Via offers the vision of an international agricultural economy composed of diverse national agricultural economies trading with one another but focused primarily on domestic production.
Once regarded as relics of the pre-industrial era, peasants are now leading the opposition to a capitalist industrial agriculture that would consign them to the dustbin of history. They have become what Karl Marx described as a politically conscious "class for itself," contradicting his predictions about their demise. With the global food crisis, they are moving to center stage--and they have allies and supporters. For as peasants refuse to go gently into that good night and fight de-peasantization, developments in the twenty-first century are revealing the panacea of globalized capitalist industrial agriculture to be a nightmare. With environmental crises multiplying, the social dysfunctions of urban-industrial life piling up and industrialized agriculture creating greater food insecurity, the farmers' movement increasingly has relevance not only to peasants but to everyone threatened by the catastrophic consequences of global capital's vision for organizing production, community and life itself.


With expressions such as, "Born in my heart", "Adoption=Love", and "Does your family tree have room for one more?", these custom stamps are a sweet way to spread a little adoption cheer whether you're writing friends and family or just paying the bills.
2) Share your feelings about adoption on your favorite social media outlets.
This is such an easy way to share a bit of your heart with all the people you care about to help them better understand the joy adoption can bring. You never know whose heart you might move to consider adoption by sharing just a little.
3) Buy an adoption-themed book or check one out from your local library.
4) Donate a little time or money to a local agency that helps children find forever families.
Some of these agencies run "Heart Galleries" or "Wednesday's Child" programs to raise awareness for local children who have not yet been adopted. They are always in need of volunteers and donations. With Christmas just around the corner, many children they work with are facing a holiday season without presents. Any little bit you can put together can make a huge difference in the lives of these waiting children. Click here to find a Heart Gallery in your state.
5) Download or order a free adoption poster to share.
The Dave Thomas Foundation for Adoption has a wealth of adoption posters, videos, and other resources available on their website, www.davethomasfoundation.org. You can email them, post them on social media, or even hang them in your church, office, or anywhere else you'd like to spread the word.


Strengthen the role of local governments, their associations and NALAS in implementation of the regional economic development agenda led by RCC and the EC in the frame of SEE 2020 Strategy and MAP-REA.
Increase demand for and utilization of existing methodological tools produced by UPP, NALAS and other partners.
Showcase best practices in local economic development.


Gaylord hockey coach Bill DeLyon had lots to cheer about last weekend. His Blue Devils rallied for a 4-3 overtime win over a rugged Cheboygan team at the Sportsplex on Friday night and followed that with a hard-fought 1-0 victory at Cheboygan the next night. Gaylord finally played up to the promise that had been there from the start of the season, improving its record to 6-8 overall and 2-3 in the Big North Conference.
What pleased DeLyon and his assistant coaches even more than the pair of wins was the manner in which Gaylord played. The Blue Devils showed self-restraint in the two games. They avoided the dumb mistakes that had cost them dearly in previous games.
In nearly four periods of play in Friday's overtime game, Gaylord was whistled for just two penalties. Saturday's game was a similar story. Because the Blue Devils didn't beat themselves, they gave themselves the chance to beat a pretty good Cheboygan team twice in a row.
DeLyon was delighted with his team's performance. "We absolutely saw what we wanted to see," he told reporters after Friday's game at the Sportsplex. "The kids are finally getting the message. You can't win games from the penalty box."
The Blue Devils had held a players-only meeting that lasted an hour-and-a-half two days prior to the opening of the series with Cheboygan.
"We aired things out and talked about how we wanted things to go for the rest of the season," said junior defenseman Dan Lubelan. "We looked at [the Cheboygan series] like it was a new start."
GHS graduate Luke Johnson was among three seniors from the Central Michigan University basketball team featured during halftime of the PBS broadcast of CMU's game with Ohio on Wednesday night.
Johnson and teammates Tim Kisner and Jon Borovich talked about their friendship, the team's turnaround this season and their role as seniors.
Luke has been used mostly as coach Jay Smith's sixth man this season. In Wednesday's exciting 75-69 victory, he was instrumental in putting the Chippewas on top late in the second half when he made a steal and passed to teammate David Webber for a fast-break layup and a 56-55 lead.


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Health professionals and health-affected organizations continue to bring powerful voices to a range of environmental campaigns, building on work that was seeded by Beldon more than a decade ago.
Beldon invested in environmental health both to change policy and to help the larger environmental community more effectively reach people beyond its traditional base. As it surveyed the landscape, Beldon chose to invest deeply in health professionals and in organizations that could speak directly to the health effects of chemicals in the environment. By directly funding organizations led by nurses, breast cancer survivors, and others, Beldon sought to add credibility and political muscle to policy campaigns. Many of the advocates whom Beldon supported continue to be active today, and leaders of state and national coalitions consistently highlight the voices of health constituencies in their policy campaigns.
Evidence of Beldon's ongoing impact can be seen in efforts like the Campaign for Safe Cosmetics, which educates the public and mobilizes consumers to take action. Spearheaded by the Breast Cancer Fund, the campaign has reached mainstream audiences, building awareness about a host of chemicals few people can even pronounce. Among its victories, the Campaign for Safe Cosmetics takes credit for helping to convince Johnson & Johnson to commit to using safer ingredients in the cosmetics it produces and distributes worldwide.
Many observers of Beldon's work point to its signature investment in nurses as both a legacy and a lesson for others. Early on, Beldon recognized the power of nurses as advocates on a local level and power players on federal policy. It invested heavily in the national organization representing nurses, only to discover that internal issues within that organization prevented it from making a meaningful contribution to the effort. This realization disappointed many, and left open the question of whether nurses would disappear from the effort when Beldon's funding ended. Five years later, high-profile organizations of nurses do not figure prominently at the national level, but nurses are still involved as advocates and spokespeople for environmental health campaigns around the country (see snapshot).
As a close colleague and Beldon partner, the John Merck Fund has continued its work to expand the voices of health professionals and health-affected constituencies. Its focus has been on a slightly different set of players, but its work has been directly informed by the Beldon experience. By helping its grantees frame their campaigns around protecting the population from chemical exposure during their first days and months of life, they are working with health professionals who specialize in prenatal and infant care. Advocates report that the leadership of mainstream medical organizations representing obstetricians and reproductive health doctors has actively taken up the cause, becoming advocates for chemicals policy reform on Capitol Hill. For these professionals, reducing human exposure to chemicals is a high priority.
The ultimate evidence of the effectiveness of Beldon's strategy to engage constituencies beyond the environmental base is evident in campaigns outside of the chemicals policy arena. Health professionals are actively recruited to join climate and energy debates and are involved in the growing citizen movement to stop the pollution created by the hydraulic fracturing process. Interviewees emphasized the value of the relationships that were built between environmental advocates and these constituencies during the Beldon years, pointing out that the alliances that were formed are now expanding their focus to other pressing environmental health issues.
Beldon's strategy to cultivate and support nontraditional voices in its environmental health program included making grants to organizations with name recognition like the American Nurses Association and the Breast Cancer Fund. In the midst of this cluster of groups was a less obvious grantee: the University of Maryland School of Nursing.
The grant supported the work of Dr. Barbara Sattler, an Associate Professor in the School of Nursing and the Director of the Center for Occupational and Environmental Health and Justice. Dr. Sattler was working to integrate environmental health into the curriculum of nursing schools. Given Beldon's focus on advocacy and policy change, the University of Maryland might seem an unlikely grantee, but Sattler's passion aligned well with Beldon's vision. She believed that the next generation of nurses needed to understand the connection between the environment and human health, so that they could be better nurses and more effective advocates for patients, and in their workplaces and communities.
An experienced professional and seasoned activist, Dr. Sattler had worked for years to protect communities from the health effects of pollution. She understood the powerful role that nurses can play in educating others, including policy-makers, and was committed to supporting more nurses as informed advocates and community leaders.
Five years of funding from Beldon enabled Sattler to sustain her work at UMD and incubate an idea for creating an organization to spread the work further. Just as Beldon was making its final grants, the Alliance of Nurses for Healthy Environments (ANHE) was born. Sattler draws a direct line between Beldon's early grants and the work she is doing now. "It was the enabling funding that we got from Beldon that helped us launch." And she credits Beldon with invaluable support, advice, and introductions to other donors, including a key funder that stepped in to support the work after Beldon left.
Today, ANHE is a network of more than 3,000 nurses working to integrate environmental health into nursing education, greening their work places, and speaking out in public policy debates. Its members are an integral part of the state and national coalitions working on chemicals policy reform. It is also working to help coordinate state nurses associations to be more engaged in these efforts. Environmental health campaign leaders describe ANHE members as "worker bees" and consider them a core part of the field operation, underscoring the value they provide to the collective effort.
ANHE may not have a high public profile, but Dr. Sattler's commitment to building a national coalition of nurses advocating for a healthy environment is bearing fruit. Although the organization continues to struggle for funding, its members have expanded their scope and are now raising their voices on energy policies, climate change, hydraulic fracturing, and other front-page issues.


Prolific author and master of copywriting, Robert W. Bly, will join us to discuss how he makes a significant income from information products, and how you can too! Join us and learn how to leverage your expertise and your audience to make more money.
Bob Bly is a freelance copywriter and marketing consultant with 3 decades of experience in business-to-business and direct response marketing. Bob is the author of more than 70 books including The Complete Idiot's Guide To Direct Marketing (Alpha Books) and The Copywriter's Handbook (Henry Holt & Co.). His articles have appeared in numerous publications such as DM News, Writer's Digest, Amtrak Express, Cosmopolitan, Inside Direct Mail, and Bits & Pieces for Salespeople. For more information, visit http://Bly.com.


text:
"We Like Killing Off The Pretty Boys"
Words by Mr Sanjiv Bhattacharya | Photography by Ms Ye Rin Mok | Styling by Ms Gaelle Paul
Who's the biggest diva on the Game Of Thrones set? It's not who you'd expect.
We're waiting in a photo studio in West Hollywood for the creators of Game Of Thrones, Messrs David Benioff (above, left) and Dan Weiss (above, right). They're late but, like winter, they're coming. With the premiere of season six of the world's biggest TV phenomenon only days away when we meet, the Two Ds, as they're known, are busier than ever. Have they – aha – hit a wall?
Game Of Thrones is now such a success that it's easy to forget its rocky start. HBO was in two minds about the pilot. All those characters and settings. The complicated world of the story. Who and what was it even about, anyway? But it eventually gave the creators a season to prove their worth. "That first year felt very probationary," Mr Benioff told The Hollywood Reporter. And then it took off. With every episode and every season, the audience grew like the armies of Daenerys Stormborn. This is a show that shoots in Northern Ireland, Spain and Croatia, with crews of up to 750 people. It's a monster.
Season six may be the most anticipated of all. Epic stories are converging with lead characters – Arya Stark, Jaime Lannister, Daenerys, Cersei, Bran, Sansa. And this is the first season in which the show departs fully from the books, forging its own path. They've been diverging for a while, but now it's complete. As fans know, the books' author Mr George RR Martin still hasn't finished his latest instalment, The Winds Of Winter.
So we're all wondering: who's going to get slaughtered and in what gruesome fashion? Will the dragons torch the armies of Westeros? Will Arya and Hodor finally... Ah, here they are now. Two tall, Caucasian men marching in – White Walkers, if you will – both glued to their iron thrones, sorry, iPhones.
Let the Game begin.
Mr Dan Weiss
Mr David Benioff
How big is your cast at this point?
Mr Benioff: I haven't counted, but on our call sheets everyone gets a number. Peter Dinklage is number one, and we're up to, I think, 544 now.

 Mr Weiss: Yeah, 544. I remember that guy. Total dick.
Tell us your favourite Mr Peter Dinklage story.
Mr Benioff: On Episode 209, he had to spend every night standing around in the dark, in constant 360º rain, covered in mud for 10 hours. For weeks on end. But there was never a complaint. He would pose for prospective metal album covers with his armour; and his axe.
When you started to catch up with the books, did you consult with Mr George Martin to find out what he was writing?
Mr Benioff: Yeah, it's a constant dialogue. We go to see him in Santa Fe to ask about what he's planning and that's very helpful. But George always says there are two kinds of writers: gardeners and architects. Architects plan everything, they make blueprints, while the gardeners plant seeds and watch them grow. He's a gardener, so he lets the story take him where it will. Which means that once we caught up, he couldn't tell us what was going to happen, because he didn't know yet.
Does he get upset when you diverge from his books?
Mr Benioff: He loved our scene in season two where The Hound and Bronn meet each other in that tavern…
Where there any changes he didn't like?
Mr Weiss: It's hard for George. When we send him outlines of the season, he says it's like looking through a strange lens at the things he's working on. Especially when we cast actors who are different from the mental image he has.
Mr Benioff: Dany was meant to be taller. Littlefinger was meant to be smaller. Xaro was meant to be a lot smaller – and feminine.

 Mr Weiss: And the throne's different, too. The throne he imagined was much bigger. You had to climb up stairs to get to the seat, but it just wouldn't work on TV.
Mr Alfie Allen as Theon Greyjoy and Ms Sophie Turner as Sansa Stark. Photograph by Ms Helen Sloan/HBO
He's late on his book. Does he ever call and say, "Listen, guys, I'm a bit stuck..."
Mr Benioff: No, no, no. The books are entirely George's.
You've shot some pretty visceral scenes. We're thinking of when Cersei does that naked walk at the end, and the woman spits in her face...
Mr Benioff: Yeah, I'm surprised Lena didn't throw up.

 Mr Weiss: It was just some fake spit thing. There are experts who make that stuff. Fake poop, too.
Was it hard to persuade her to go through all that?
Mr Benioff: That was a rough two-day shoot. But Lena had known that scene was coming for a long time. It's a remarkable scene. She's not the kind of actor who stops weeping when we say cut. Whatever she was accessing, it felt very real. She'd gone somewhere dark.

 Mr Weiss: She was probably thinking about the fact that she had to have dinner; with us afterwards.
What's the most challenging scene you've shot?
Mr Benioff: It's in season six, actually. There's a big battle that involved 60 horses. And horses are dangerous. They can freak out. So, of course, we shot a scene with a bunch of horses thundering towards one of our characters and pulling up short. It'd be so easy to fake with visual effects, but for some reason we didn't. And I remember thinking, "Oh god, that actor would be expensive to replace.".
Are horses as demanding as actors on set?
Mr Weiss: The bear; in season three was more demanding. If he did a good take – I'm not joking – everyone on set had to clap: "Good job, Bart!" He'd only work for 10 minutes, then he'd go back to his trailer where he listened to country music really loud, because it calmed him. And he needed a constant supply of whipped cream pies. Total diva.
Do you take a perverse pleasure in killing series leads?
Mr Benioff: I like killing the pretty boys because it makes my wife so angry. So Robb Stark, Jon Snow – they were good.
Jaime Lannister needs to watch his back.
Mr Weiss: He sure does. What a dick!

Mr Benioff: The Danish dick!
When you're going to kill off a key character, do you show up on the actor's doorstep in uniform?
Mr Weiss: No, it's a phone call. The Death Call. People know that if you get a call from the two of us at once, it means you're going to die. It's the bell tolling.

 Mr Benioff: Except we did call Nikolaj once about something else, and it freaked him out.
Do you know how many more seasons are left?
Mr Benioff: Yes, but I'm not allowed to tell you.
Do you feel an obligation to surprise people with the ending?
Mr Benioff: Not really. Maybe for us, the surprising ending is a non-surprising ending. Such as the Breaking Bad ending – that was great, it really worked. But it wasn't shocking.

 Mr Weiss: We can do both, though, because we've got so many characters and plot lines. We won't have just one ending. It'll be a mix.
But you know how it ends?
Mr Weiss: We figured it out by season two. It's like an unfocused image that gradually comes into focus as you get closer.
Mr Weiss: Basically, we started with the ending – Hodor sitting on the Iron Throne – and worked backwards from there.
Season six of Game Of Thrones is showing now


text:
OK State launches website to respond to SI allegations
KFOR.com
STILLWATER, Okla. – As the fourth part of a five-part series was released from Sports Illustrated detailing alleged misconduct by the OSU football team, Oklahoma State President Burns Hargis is speaking out about the accusations.
"As we have said, we will investigate the accuracy of the allegations and take all appropriate action," OSU President Burns Hargis said. "We do not condone or tolerate improper conduct in our athletic programs."
In Friday's statement, Hargis says they will get to the bottom of the accusations and that he believes the current staff is committed to making sure the program is at its best.
He said, "At OSU, sure we want to win. But we want to win the right way."
Watch the full statement here.
University officials said they have contacted the NCAA and advised it of the accusations.
OSU Vice President of Athletics Mike Holder said, "We take the allegations seriously…