text:
Gabriele Rommel, geb. Oelsner, (* 1953 in Leipzig) ist eine deutsche Germanistin.

Sie promovierte 1978 und habilitierte sich an der Universität Leipzig. Das Thema ihrer 1979 vorgelegten Dissertation A lautet Der Mensch als Universum. Die Verteidigung des Humanismus in den Studien und Fragmenten Friedrich von Hardenbergs (Novalis). Von April 1992 bis August 2019 war Gabriele Rommel Direktorin der Novalis-Forschungsstätte und Novalis-Museum Schloss Oberwiederstedt. In dieser Funktion gestaltete sie mehrere Ausstellungen und legte zahlreiche wissenschaftliche Publikationen zum Dichter der Frühromantik, Friedrich von Hardenberg, und dessen Umfeld vor.

Ehrungen
Im April 2022 erhielt sie als Novalis-Museumsdirektorin den Bundesverdienstorden verliehen.

Weblinks

Einzelnachweise

Germanist
Novalis
Träger des Bundesverdienstkreuzes am Bande
Deutscher
DDR-Bürger
Geboren 1953
Frau


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text:
John Malcolm Greany, meist J. Malcolm Greany (* 23. April 1915 in Philadelphia; † 27. Juli 1999 in Hood River, Oregon), war ein US-amerikanischer Naturfotograf.

Leben
Greany wuchs in Detroit auf und kam 1936 kam zum ersten Mal nach Juneau, Alaska, wo er das Fotografien erlernte. Im gleichen Jahr begleitete er Reverend Bernard Hubbard auf einer Expedition entlang des Taku River. Nach seiner Heirat 1938 siedelte Greany mit seiner Frau dauerhaft nach Juneau über. Im Zweiten Weltkrieg arbeitete er als Fotograf der US-Armee, unter anderem auf der "MS Brown Bear" im Gebiet der Aleuten. Auf der westlichsten Aleuten-Insel Attu fotografierte er im Sommer 1941 die Einheimischen und ihre Lebensweise. 1942 wurde die Insel von der japanischen Armee eingenommen und die Bevölkerung deportiert. Nur 25 der ursprünglich 47 Einwohner überlebten, die Siedlung auf Attu wurde nie wieder neu errichtet. Greanys Fotos sind daher die letzten Dokumente über die Bevölkerung Attus. Im September 1944 begleitete Greany als Fotograf eine Suchexpedition der Armee nach einer in unkartiertem Gebiet östlich des Mount McKinley abgestürzten Douglas DC-3.
 Später war Greany als freier Fotograf und für verschiedene öffentliche und staatliche Ämter in Alaska tätig, zuletzt für den US Forest Service in Missoula. Seine Naturfotografien wurden international bekannt und erschienen unter anderem im Time Magazine und bei National Geographic. Bekannt wurden auch seine Porträtaufnahmen von Ansel Adams, mit dem ihn eine langjährige Freundschaft und Zusammenarbeit verband. Im Gegenzug fertigte Adams auch Aufnahmen von Greany an.

1974 setzte sich Greany in Hood River, der Geburtsstadt seiner Frau Irene, zur Ruhe. Mit Irene war er 61 Jahre, bis zu seinem Tod 1999, verheiratet, das Paar hatte fünf gemeinsame Kinder.

Veröffentlichungen
 Alaskan Cookbook. Howell-North, 1960 (mit Fotografien von M. Greany)

Weblinks
 J. Malcolm Greany Papers and Photographs, Aleutian Islands, 1941. Alaska Digital Archives

Einzelnachweise

Naturfotograf
US-Amerikaner
Geboren 1915
Gestorben 1999
Mann

redpajama_set_name: RedPajamaWikipedia


Air Velocity Sensor Structure: Conventional twisted vane arms and low-friction ball-bearing design.
Operating Conditions: Temp: 0 to 50 (32 to 122 ). Humidity: Less than 80 % RH.
Accuracy: 3% FS process gas: 32 to 122°F (0 to 50°C); 4% FS process gas: -40 to 32°F 122 to 212°F (-40 to 0°C 50 to 100°C).
Temperature Limits: Process: -40 to 212°F (-40 to 100°C); Ambient: 32 to 140°F (0 to 60°C).
- 0.2 - 20.0 m/s, high precision for low air velocity measurement, Telescope probe.
- m/s, ft/min, km/h, knots, mile/h, oC/oF.
- Max., Min., Data hold, RS-232.
In order to keep pace with never ending demands of clients, our company offers Anemometer.


Description Mina Bruer, Jenny Ware, John N. Bruer, Nora Bruer, and Reverend John Poehl sit on a sofa in a parlor. The room in this 4" x 6" black and white photograph has floral wallpaper, a framed portrait on the wall behind the sofa, and a window with a lace curtain. There is a piano on the right side of the photograph with a piece of sheet music on it. The two men in the photograph are wearing suits and ties, and the young women are wearing blouses and long skirts. Mina, the youngest girl, wears a dress with plain trim and a matching plaid bow in her hair.
Notes This photograph was taken in the Bruers' formal parlor as Reverend Poehl was courting Miss Nora Bruer. John H. Bruer is pictured in the photo on the wall. John Poehl was a Methodist Preacher in Crawford for a short time in early 1900s.


text:
Home/Technical Advisory Council
Technical Advisory CouncilGreg2021-09-23T16:14:32-07:00
Dr. Russell Harmon, Chairman
Dr. Russell Harmon is a geochemist, now retired after a nearly 50-yr professional career in the geosciences. From 2011-17, Russell was Director of the International Research Office of the US Army Engineer Research and Development Center. Prior to that, he served from 1993-2011 as Program Manager for Terrestrial Sciences at the Army Research Office. Russell also has worked in the Lunar Receiving Laboratory and Geochemistry Division at the NASA Manned Spacecraft Center, at the Scottish Universities Research and Reactor Center, in the UK Natural Environment Research Council and has held faculty positions at Michigan State University and Southern Methodist University. He is a Fellow of the Geological Society of America and National Speleological Society, past Chair of the Geological Society of America Division of Mineralogy, Geochemistry, Petrology, & Volcanology and a former President of the International Association of GeoChemistry. His current research interests include riverine geochemistry and laser-induced breakdown spectroscopy. Russell holds a BA from the University of Texas, MS from the Pennsylvania State University, and PhD from McMaster University.
Dr. David Hedley MacDonald Alderton
Dr. Alderton is an Honorary Research Associate in the Department of Earth Sciences at Royal Holloway, University of London, UK. Formerly a lecturer in Geology at Royal Holloway with over 35 years of experience teaching at undergraduate and postgraduate levels, his research using field and laboratory-based studies has been carried out at numerous locations around the globe. The results of this research have been widely published, with the focus on two broad themes: the characteristics and genesis of hydrothermal, metalliferous mineral deposits, and the geochemistry of mining-related pollution. Dr. Alderton's collaboration with the mining and engineering industry has concentrated on the chemical and mineralogical characterization of mining waste and minimizing its effect on the environment.
Professor R. Baskar
Prof. R. Baskar is a Professor in the Department of Environmental Science and Engineering, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India. He has also been an Academic Guest in the Swiss Federal Institute of Technology (ETH), Zurich, Switzerland, Technical University of Munich, Germany, Centre for Geobiology, Norway, Stockholm University, Sweden, VTT, Finland, Jagiellonian University, Poland and Slovak Caves Administration, Slovakia. He actively takes part in several national and international conferences, workshops, field work and training programs, including outreach activities. Prof. Baskar has been professing for the seamless integration of geology and microbiology and has been one of the pioneering Indian workers in cave geomicrobiology. He has published several research papers along with other workers, which has resulted in the significant advancement of fundamental knowledge about mineral-microbe interactions. Prof. Baskar believes that public engagement with science is essential for a high level of outreach activities and delivers popular scientific lectures in schools, colleges, universities, and publishes popular science articles.
Dr. Hamida Diab
Dr. Hamida Diab holds degrees in Geology from the University of Annaba, Algeria (PhD) and the University of Tebessa (BSc and MSc). She has more than 11 years of experience in minerals exploration and exploitation, sedimentary geology, geochemistry, environmental geology, structural and field geology, petrology, and geotechnical applications. She has experience with several mining companies in technical and administrative positions, including as the Technical Coordinator at the National Office of Geological and Mining Research (ORGM). She is currently a Project manager at the National Iron Mining Company (SOMIFER).
Dr. Diab has authored or co-authored more than 10 scientific publications, books, and abstracts, as well as several presentations at national and international conferences in the field of earth science. She has a great passion for geology and aspires to use it to improve the lives of people and communities.
Dr. Mike Katz
Dr. Mike Katz received a BS in Geology from Michigan Tech in 1960, a MSc from McGill in 1963 and a PhD from the University of Toronto in 1967. He was a senior lecturer in Applied Geology from 1971 to 1988 and Director Key Centre for Mines International (KCMI) 1988 to 2009, University of New South Wales (UNSW), Sydney, Australia.
Mike has over 50 years international experience starting up with a Canadian Government assignment for the establishment of the first Department of Geology in Sri Lanka from 1967 to 1970 and later as a Councillor for the AGID from 1976 to 1984. With the KCMI, he has worked with AUSAID, UNDP, WB and ADB on over 70 projects in 25 countries. From 1960 to 1967, Mike worked in Canada in mineral exploration and as a geologist for the GSC and the Quebec Government. On retirement from the UNSW in 2010, he has worked for the UNDP in Cambodia, the APEC mining task force, the IM4DC and the Australia Award Africa program. Mike is now a reviewer for the IUCN UNESCO World Heritage geological sites and has recently initiated a social responsibility for geoscience education project.
Dr. Yousif K. Kharaka
Dr. Yousif Kharaka is a senior research hydrogeochemist (emeritus since, 2012) with the U.
S. Geological Survey, Menlo Park, California. As a Research Scientist at the University of California, Berkeley (1971-1995), and at USGS since 1975, he has been conducting field and laboratory geochemical investigations in the broad areas of water-gas-rock interactions in a variety of natural and contaminated systems. His current investigations cover naturally occurring organics, organic-inorganic interactions, CO2 sequestration in saline aquifers and depleted oil and gas reservoirs, remediation of contaminated agricultural drainage, environmental impacts of water produced with petroleum, and the role of fluids on the dynamics of the San Andreas Fault system.
Dr. Kharaka received his B.Sc. (honors) from Kings College, London, in 1963, and his Ph.D. from the University of California, Berkeley, in 1971. He is currently an associate editor of Applied Geochemistry. Dr. Kharaka was the Secretary General for the Seventh International Symposium on Water-Rock Interaction (1992) and was the Chairman of the Working Group on Water-Rock Interaction of International Association of GeoChemistry (IAGC) from 2001 to 2007. He was also a Member of the AAPG Global Climate Change Committee (2007-2010).
Dr. Gabriela Perlingeiro Knesel
Dr. Knesel holds degrees in Geology from The University of Queensland (PhD) in Australia and University of São Paulo (BSc) in Brazil, as well as an MBA in Finance from Rome Business School in Italy. She has over 13 years of experience in earth sciences, particularly in the areas of geochemistry, geochronology and petrology, and has conducted fieldwork on four continents. Dr. Knesel works for the Lhoist Group, currently managing the overall mine plan of an 8.5 Mt mine in Texas, following posts within Lhoist's Global R&D and North American Mining & Exploration teams. She represented Australia as part of the YES Network Leadership Team until she moved to Belgium in 2013, and was the lead organizer of the 2nd World YES Congress, held within the prestigious 34th International Geological Congress in Brisbane in 2012 (with 6000+ attendees). She is a supporter and advocate for women in the mining and metals industry.
Mr. Alex Kwatampora Binego
Mr. Alex Kwatampora Binego is a geoscientist, a geotechnical engineer, and a mining, and engineering geologist with 28 years of experience. He is the Executive Managing Director of Mpora Geo-Tech Consultants Ltd. in Uganda and has worked as a Senior Engineering Geologist-Geotech/Materials Engineer with Fichtner Gmbh & Co. Kg in Germany, as Project Manager of Kilembe Mines (copper and cobalt mine), as Senior Geologist and Transaction Advisor to DLA PIPER (USA), and as a Technical Consultant to M2 Cobalt Corp. (Canada) and JERVOIS Mining Ltd. (Australia)
He has an MSc in Geoscience (Geotechnical Engineering) from Atlantic International University, a BSc (Hons) in Mining/Engineering Geology, Diploma in Earth Science, Seismology Hazard Assessment and Risk Mitigation, from Middleham University and the University of Pretoria, and certificates in Mineral Resources Exploration, GIS & Remote Sensing (Korean Institute of Geosciences and Mineral Exploration, South Korea), Public Administration and Management (Makerere University, Uganda), Geophysics and Seismology (National Research Institute of Astronomy and Geophysics, Egypt), Seismology, Nuclear Radiation, and Safety (Institute of Seismology, Nuclear Radiation, and Detection, Helsinki) and in Development Studies – Poverty Alleviation (Zhejiang University, China).
Alex is a member of the International Association for Promoting Geo-Ethics (IAPG # 2843), a Life member of the Geological Society of Uganda, and a member of the Uganda Seismic Safety Association, the Association of Environmental & Engineering Geologists (AEG) and the Uganda Chamber of Mines & Petroleum (UCMP), as well as an ISO certified Auditor QMS 9005 – 2015.
Dr. William Berry Lyons
Dr. Lyons is a Distinguished Professor, College of Arts and Sciences, School of Earth Sciences, and Senior Research Scientist at the Byrd Polar and Climate Research Center, The Ohio State University. Lyons and his research group currently conduct research on three specific topics: 1. the biogeochemistry of Antarctic terrestrial/aquatic ecosystems and how they respond to climate change, 2. the interactions and rates of chemical weathering, erosion/sediment transport and carbon dynamics, especially in small, mountainous watersheds, and 3. the impact of urbanization, suburbanization and agricultural activities on water quality. He is a Fellow of GSA, AAAS and AGU. He has been the lead investigator of the McMurdo Dry Valleys Long Term Ecological Research program, one of the two Antarctic LTER sites funded by the National Science Foundation. Dr. Lyons is also a U.S. representative on the Geosciences Scientific Group of the Scientific Committee for Antarctic Research (SCAR), and the former Director of the School of Earth Sciences, and the Byrd Polar and Climate Research Center at OSU.
Dr. Francisco E. Nullo
Dr. Francisco E. Nullo was born in Buenos Aires, Argentina. He was a senior researcher at the National Geological Service (SEGEMAR) from 1967 to 1999, and a principal research scientist at Argentina's National Council for Scientific and Technical Research (CONICET). He has carried out numerous investigations in regional geology, mining, environmental geology, volcanology and paleontology. He was a professor of Regional Geology at various universities in Argentina and Brazil: Buenos Aires, La Pampa, Rio Cuarto, Córdoba, Bahía Blanca and Rio Grande do Sul. More than 20 years ago, Dr. Nullo and his son founded Newphoenix SRL consulting, carrying out research in various specialties of applied geology. He participated as an expert in the UN's seafloor mining program and was an advisor to the IDB in the Republic of Paraguay. Dr. Nullo has directed numerous research projects at Masters and PhD levels. He is currently studying the environmental conditions for the installation of numerous waste repositories in the country, financed by international credit organizations.
Mr. Nathaniel G. Wessel
Mr. Wessel holds a BSc in Computer Science and a BSc in Psychology from Colorado State University. He is currently a Lead Firmware Engineer and Architect for Micron Engineering, where he develops non-volatile storage devices. In those moments when he is not working, he can be found backpacking, changing diapers, chasing toddlers, gardening, riding his dirt bike, or being tackled by his dogs. Mr. Wessel is well traveled and exceptionally versed in internet applications to marketing and development. He has also worked with a number of companies to maintain and upgrade their corporate computer systems, implemented predictive analytics, provided customer support for a variety of platforms and mobile devices, and worked with other scientists and engineers to develop new products for biological applications.
Chaired by Dr. Russell Harmon, GPI's Technical Advisory Council provides scientific and technical guidance and oversight of existing and proposed activities and programs as requested by the Board. The TAC members are highly respected and qualified geoscientists who can address a wide variety of geologic issues in all environments.

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Having 2 responsive Divs Side By side So basically I am trying to make a page with 2 responsive columns, the same size side by side and instead of using px for measurement I'm sizing them using percentage. No matter what I do, setting both divs to have a margin of 5% and width of 40% they should sit side by side in a container with 'display: inline-block'. But for some reason it's not.
Here's the J-Fiddle demonstrating my issue. I have content above and below these divs on the page I'm working on... so they can't interfere with that, using, declaring float positions just seems to complicate things further.
http://jsfiddle.net/avh9s6pa/
If you guys could help I'd really appreciate it. It'll be something simple no doubt, but it's driving me nuts.
.post-reg-columns {
    width: 100%;
    display:block;

}

.firstcolumn {
    display: inline-block;
    max-width: 40%;
    margin:5%;
    padding:10px;

}

.firstcolumn button {

    color: #fff;
    background-color: #6496c8;
    text-shadow: -1px 1px #417cb9;
    border: none;
    font-size: 1.4em;
    font-family: 'Bree Serif', serif;
    font-weight:bold;
    width: 100%;
    padding:15px;

}

.firstcolumn button:hover {
    background-color: #416386;

    }

.secondcolumn {
    display: inline-block;
    background:#fff7ca;
    max-width: 40%;
    margin:5%;
    padding:10px;

}

 Basic Listing

            <button>Test Button</button>
            ewfwefw efwefwefw fwefwef wefwefwef wefwefwe fwefwef wefefw efwe fefwefwefw eiofj erio jweriojgjphi owriog jerioj gerijg ejfwefwef wefj weijfwe jfjiw efjwej wef weijf hello this is a test blah blah blah! My name is Chris Mayberry and this is a test

            Lorem ipsum dolor sit amet, consectetur adipiscing elit. Sed euismod sollicitudin magna, sed placerat dui pretium quis. Vivamus sit amet velit nisi. Etiam consectetur mauris ligula, id fermentum felis fermentum ac. Phasellus pharetra a lorem ac dictum. Nullam vitae tempor ex. Mauris in vehicula augue. Maecenas sit amet porttitor enim, eu vehicula orci. Aliquam id nisl non sem mattis varius in sed nulla. Nulla ultrices fringilla erat, vitae tincidunt turpis malesuada vitae. Cras vehicula ex at arcu eleifend cursus. Sed varius dignissim risus eu fringilla.

A: As per your code, both divs have 40% width which means total 80%. Further, 5% margin which mean 5*4 =20%. So total becomes 100% here. And in your second div it has also 5% margin which force it to break as (100%+20%) there is no more space. You need to remove margin:5%; from .firstcolumn.
Check this fiddel

A: Remove margin:5%; from .firstcolumn class.
Demo here
Update answer
.post-reg-columns {
    width: 100%;
    display:block;
    margin:5%
}

Demo Here

redpajama_set_name: RedPajamaStackExchange


text:
Lukas Lekavičius, who is trying to forget the painful defeat at EČ so far, has participated in four "Žalgiris" training sessions where strong defense is emphasized.
Kaunas basketball player "Zalgiris" will play the final off-season match on Thursday evening in the training hall of "Zalgiris" Arena. The final test of strength before the official start of the season will be conducted by ក្រុមalgiris against Riga VEF.
Before the match, which will start at 18:00 and will be broadcast live by "galgiris Insider" to the client of MVP plan, defender Kaunas Lukas Lekavičius spoke with "galgiris TV" about his situation and the team before The end of the season. Preparation.
"Of course there was not much training, maybe they missed a bit because we were recently involved. We may have four coaches, but the good thing is we know the coaches. We know his system in almost every combination. There are differences, but we are still learning. "I think everything is fine and we will be ready," Lekavičius explained.
The attacking midfielder took part in the team's training after last week's European Men's Basketball Tournament and in Monday's non-season match against Wolves he ran on the floor in less than 10 minutes.
According to Lekavičius, after joining the team, he saw a positive image – a team capable of actively defending and attacking.
"It is very difficult. The coach gave him some rest. I tried to remove my head from the national team, we really had a painful defeat. Coming to the game was not easy, there was little training, but the team left a good impression. I think we are very energetic, we are very defensive, we play very well. This scene really makes me happy.
Speaking about the team's game and its possibilities, Lekavičius mentioned that the "galgiris" coaches, who are younger and more energetic, emphasize the work of Zalgiris on the side of their pitch.
"The coach emphasizes in training that we will try to put pressure on opponents, trade defenders, be aggressive, not allow the ball, not give other teams a chance to breathe. We have and offensive weapons – we will be able to run for quick attacks. Also, we are very good players. "I think this is where our strengths will be."
L. Lekavičius, 28, is preparing for his seventh season in Kaunas so he can be called one of the most experienced basketball players in the locker room. The defender smiles when asked about his veteran condition.
"It's a bit strange to be a veteran. I was sitting next to Kalnietis in the dressing room. I approached the veteran in the locker room. The feeling is interesting. It always happens that new players come in and old ones leave. Lekavičius said.
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text:
Xie Wenjun ( * 11. Juli 1990 in Shanghai) ist ein chinesischer Hürdenläufer, der sich auf die 110-Meter-Distanz spezialisiert hat.

Sportliche Laufbahn
Erste internationale Erfahrungen sammelte Xie Wenjun bei der Sommer-Universiade 2009 in Belgrad, bei denen er mit 13,93 s im Halbfinale ausschied.2012 qualifizierte er sich erstmals für die Olympischen Spiele in London, bei denen er mit 13,34 s im Halbfinale ausschied. Im Jahr darauf nahm er an den Weltmeisterschaften in Moskau teil und schied dort mit 13,59 s im Vorlauf aus. 2014 erreichte er bei den Hallenweltmeisterschaften in Sopot über 60 m Hürden das Halbfinale, wurde beim Leichtathletik-Continental-Cup in Marrakesch Vierter und siegte bei den Asienspielen im südkoreanischen Incheon in 13,36 s.

2015 siegte er bei den Asienmeisterschaften in Wuhan und qualifizierte sich damit für die Weltmeisterschaften in Peking, bei denen er mit 13,39 s im Halbfinale ausschied. Im folgenden Jahr erreichte er bei den Hallenweltmeisterschaften in Portland das Halbfinale und schied bei den Olympischen Spielen in Rio de Janeiro mit 13,69 s in der ersten Runde aus. 2017 nahm er ein weiteres Mal an den Weltmeisterschaften in London teil und erreichte dort erneut das Halbfinale, in dem er mit 13,36 s ausschied. Bei den Hallenweltmeisterschaften in Birmingham erreichte er abermals das Halbfinale und siegte Ende August in 13,34 s erneut bei den Asienspielen in Jakarta. Im Jahr darauf siegte er bei den Asienmeisterschaften in Doha mit neuer Weltjahresbestleistung und persönlichem Rekord von 13,21 s. Damit qualifizierte er sich erneut für die Weltmeisterschaften, die ebenfalls in Doha stattfanden und gelangte dort bis in das Finale, in dem er in 13,29 s den fünften Platz belegte. 2021 startete er erneut bei den Olympischen Spielen in Tokio und schied diesmal mit 13,58 s im Halbfinale aus.

2022 schied er bei den Weltmeisterschaften in Eugene mit 13,58 s in der ersten Runde über 110 m Hürden aus.

In den Jahren 2008 und 2012 sowie 2015, 2018 und 2020 wurde Xie chinesischer Meister im 110-Meter-Hürdenlauf. Er absolvierte ein Marketingstudium an der Tongji-Universität in Shanghai.

Persönliche Bestzeiten
 110 m Hürden: 13,17 s (+0,7 m/s), 18. Mai 2019 in Shanghai
 60 m Hürden (Halle): 7,60 s, 16. Februar 2013 in Birmingham

Weblinks

Einzelnachweise

110-Meter-Hürdenläufer (China)
Olympiateilnehmer (China)
Teilnehmer der Olympischen Sommerspiele 2012
Teilnehmer der Olympischen Sommerspiele 2016
Teilnehmer der Olympischen Sommerspiele 2020
Teilnehmer an den Asienspielen (Volksrepublik China)
Universiadeteilnehmer (China)
Teilnehmer der Sommer-Universiade 2009
Asienspielesieger (Leichtathletik)
Asienmeister (110-Meter-Hürdenlauf)
Chinesischer Meister (Leichtathletik)
Sportler (Shanghai)
Chinese
Mann
Geboren 1990


text:
occasional words about gaming and tractors
The Alexis Kennedy Thing
A Cordial Reminder
Let It Go – A Modest Proposal
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The Unbearable Lightness Of Stranglethorn Vale
May 18, 2009 0 Scott Jennings Uncategorized
Richard Bartle explains in great detail exactly what goes through an MMO designer's mind when playing one of the more painful zones in WoW. Except he rather likes it, see.
So, my view is a bit different. As I noted, I actually see Stranglethorn Vale (STV) as one of Blizzard's less well designed zones. To wit:
It's too large, and until very recently there was no easy way to move from one end of the zone to the other. While ideally, as Bartle noticed, there is a slow progression from one end of the zone to the other, realistically players will not play through the entire zone in one sitting. This is especially annoying for Alliance players – they have a small NPC hub, without a "innkeeper" resting area, in the northern end of the zone, while Horde players have a more central location, with an innkeeper, to work from. This is really the largest problem with the zone – it's just too large. And because it's too large, it keeps you there far too long. What may have given you a sense of place and wonder at level 30, to put it mildly, no longer does by level 45. (Another zone, Dustwallow Marsh, was recently revamped specifically to give players a place to escape to during that level range.)
The quest design relies far too much on "kill 10 of these. OK, kill 10 of these! OK, hey, kill 15 of these." Yes, that's inherently what WoW (or any Dikumud PVE) game play is. But those sorts of concentrated kill quests, while gravy to powergamers looking for the easiest way to leverage the mindless button pressing that destroys them of everything that makes them human, really highlight the artificiality of the enterprise. And that's what most WoW quest design manages to hide very well. You're not just killing 10 wolves, you're saving a troll village from starvation or whatnot. Sure, it's just a storytelling veneer, but it's important veneer. It also helps break up the inherent tedium involved in "kill 10 of this, fetch 5 of that" questing. And because WoW is usually so good at this smoke-and-mirror hand waving style of quest-driven storytelling, when it breaks down, it's notable. And STV is an excellent example of where this breaks down.
Hitting more on the specifics of faulty quest design as opposed to the content, STV is where players begin to be punished in earnest by poorly thought out world design. When you have too many players hunting the same thing in the same area, you either encourage cooperation or competition. However, WoW by its very nature as a solo-friendly MMO rabidly discourages cooperation (at least until it's hit forcibly over your head when you switch to end-game raiding), so very few people actually think "Hmm – we're all hunting for 10 panthers, we should group up and kill them together!". Instead, they think "Hmm, we're all hunting for 10 panthers, I BETTER TAG THEM FIRST!". Other poorly thought out mechanics include the "Green Hills of Stranglethorn" mega-collection quest (which the author himself is on record as regretting as "the worst quest in WoW") which usually serves as a focus of inventory-related frustration for the intended new player audience and as powergaming grist for those already familiar with the zone, and some quests with an insanely low drop rate for quest-related drops that, again, encourage frustration over fun.
So, that's generally what I think of when I remember that zone – long, tedious, lots of panthers, and an abiding hatred for Hemet Nesingwary. A hatred, by the way, which Blizzard gave a knowing wink to in Northrend – after Nagarand, aka STV 2.0, reuses the kill-20-panthers quest design yet again to even more wretched excess – when you can actually start killing off Hemet's buddies. Generally, if a well-regarded part of your content involves killing off a quest giver, that may be a sign people didn't like those quests.
A lot of what Bartle writes on STV is interesting, especially as it relates to its quest design. He definitely comes at looking at STV from a different angle than I do. Specifically:
Well no, because these quests are stepped: the levels appropriate for the tiger mastery steps are 31, 33, 35, 37; for the panther mastery steps they're 31, 33, 38, 40; for the raptor mastery steps they're 34, 36, 41, 43. The final boss is also 43, but elite (so "bring friends"). This interleaving allows for variety, and it despatches the players off to various different parts of STV where the target creatures lie, thereby causing happy interactions with other quests relating to areas they pass through. However, even though this is very well done, it's basically just well-accomplished craftsmanship. No, what we also have here is some actual art.
The stepped nature of these hunting quests mean that whatever level you first encounter the Nesingwary camp in STV, there's going to be a quest of an appropriate level for you. It's like a net, spread wide to catch players.
Well, no. Thanks to how WoW quest chain dependencies work, you actually have to start at the beginning no matter what your level, and work your way through the chain. It would be awfully nice if the quest givers did actually recognize that, yes, thanks to being Level Awesome you can dispense with the Somewhat Mighty Junglecat slaying and move straight on to the Fiercely Mighty Junglecat part of the quest. (Which Warhammer Online also tried to implement, by the way.) At least, it would be if you were playing the game as designed. Players, who are playing the game to win much of the time, would then resent the loss of experience and faction and gold and everything else, and hammer away at the lower level quests despite their being level-inappropriate, because they don't want to lose any rewards due them at all. (The fact that they will then kvetch about that content being tedious is entirely beside the point.)
Bartle's primary point, to move away from nitpicking semantics, however, is that the entire Hemet Nesingwary saga is an artful storytelling device which funnels you through the wonder of the jungle, forcing you to ask if you were predator or prey, as you travel down a road which mirrors your character's growth and confidence. And as designed, the core of STV – which can easily be a metaphor for WoW's character development model itself – does indeed work that way. Proper game design (at least as one cynical wag put it) doesn't present you with a complex challenge, but tricks you into believing you've conquered a complex challenge. And in WoW, that "complex challenge" is the investment of time. Invest enough time in STV – or WoW itself – and you will eventually win. That's its inherent promise, and to a large degree the polish in which that promise has been delivered is why WoW is so incredibly popular, even years after its release.
And yet, even with that well-executed promise, there are problems along the way. Server queues. Lack of meaningful social gameplay. Class imbalance. Lack of meaningful PvP. Same old diku, different day. And STV mirrors that as well – even with all of WoW's promise, and even with STV's world design and immersive environment, there are times when it falls flat on its face.
And so we have Dustwallow Marsh. Which is everything STV isn't – a hub-spoke model of world design, less immersive world crafting, more attention to detail and interesting quest mechanics. And with a game and community the size of WoW's, this is really the solution to STV's problems – simply create so many options that everyone can be happily grinding their way to vir
tual nirvana.
SUNSWORD: NO CD FOR YOU! [Author: lum]
POLITICS IS STILL POLITICS, BULLSHIT IS STILL BULLSHIT, LETS ALL WANK OFF TO UNDERWEAR CATALOGS [Author: myschyf]
CHE, KOKO WA DOKO NANDA!? BALHAE? JODAN JA NAI! [Author: wirehead]
Next And I Beheld When He Had Opened The Sixth Seal
Previous Champions delayed to September 1
Broken Toys © 2020. All Rights Reserved.


Perfect personalised gift for nana, nanna, mummy, mum, nan, nanny, gran, granny, aunt, aunty, auntie.
This beautiful family name keyring is a feature product for Stamped A Lot.
Price stated is for the heart only. Name tags are additional.
Stamped using aluminium which is lightweight but strong and will not tarnish. These have a lovely ting sound as they are free to move around.


Welcome to sharonhubbardarts.com, the on-line gallery for Canadian artist Sharon Hubbard.
With an artistic purpose Sharon is inspired by the many artistic and photographic opportunities nature provides.
All of the material on this site, including but not limited to text, photographs, images and graphics is owned by Sharon Hubbard. This material is protected by international copyright, trademark, and other intellectual-property laws. No part of this site may be reproduced by any mechanical, photographic, or electronic process, nor may it be stored in a retrieval system, transmitted, or otherwise copied without prior written permission from Sharon Hubbard. Unless explicitly noted otherwise, you may not modify, publish, transmit, or otherwise distribute material from this site, in whole or in part, whether over the Internet or otherwise, and whether or not for payment, without prior written permission from Sharon Hubbard. Permission is hereby granted, to anyone who wishes to do so, to provide links from other Internet sites to this one.


In California, currents converge and cut new streams. Asian Pacific sensibilities permeate California's landscape from one end to the other, in its major cities--San Francisco, Sacramento, Los Angeles, San Diego--its rural outposts, and even the Silicon Valley.
The traditions of Californians of Asian and Pacific Islander descent are remembered and shared throughout California State Parks' monuments, historic parks, museums and visitors centers. The centerpiece of the China Camp State Historic Park is China Camp, the oldest (1880s) and last Chinese fishing village on San Francisco Bay. A small cluster of preserved buildings remains from the Chinese shrimp-fishing village. Tour historic structures and an interpretive display to get a feeling for life in the 20 to 30 fishing villages that once flourished in the San Francisco Bay Area.


With Mental Health Day last week, organisations are using the opportunity to reflect on their own activities and assess whether they have the right support in place. Here are five ways workplaces can ensure they are supporting their employees' mental health and creating a mentally healthy workforce.
Promoting regular conversations around wellbeing is vital and checking in regularly with members of their team, even if it's just a ten-minute conversation to ask how they are, could make all the difference to help someone open-up about their mental health.
Through sharing resources employees can be encouraged and empowered to take ownership of their own mental health. There are a number of free and practical guides available from leading mental health organisations.
If you want Wellbeing to be a focus for 2019, why not join as at the 13th Annual Workplace Wellbeing and Stress Forum in November? Click here to find out more.


Double this dose rate for very cloudy water with high levels of suspended paticulate matter.
In the event of impurities being precipitated on the pool floor, remove them by vacuuming directly to waste.
Caution Regularly check sand filter pressure and if it becomes too high, backwash and rinse to obtain a normal pressure. Cartridge filters should be chemically cleaned and rinsed regularly when using this product.


Crab cracks may be rare but the blue crab gets plenty of pertaining to charleston crab cakes in HD resoutions for free. This wallpaper was added in Tuesday, 20 March 2018 which is part of the Crab Cakes collection. It's native resolution is 682x1024 pixels.


text:
August/2018 vol. 4
Shisha waterpipe use and awareness of health risks among young adults in a semi-rural underprivileged community in North West England
Paula Jane Whittaker 1
, Happe Hoque 1, 2, Tracy Jones 2, 3
University of Manchester, Manchester, United Kingdom
Pennine Care NHS Foundation Trust, Lancashire, United Kingdom
Tameside Metropolitan Borough Council, United Kingdom
Paula Jane Whittaker
University of Manchester, Room 2.545, Stopford Building, Oxford Road, M13 9PT Manchester, United Kingdom
Submission date: 2018-05-11
Final revision date: 2018-07-30
Acceptance date: 2018-08-22
Tob. Prev. Cessation 2018;4(August):31
DOI: https://doi.org/10.18332/tpc/94507
References (12) Citations (1)
health attitudes
smoking prevalence
Study, Population Based
Waterpipe smoking has become increasingly popular among young adults across the globe. Evidence suggests waterpipes have overtaken cigarettes in popularity among university students in the UK. This survey aimed to measure the prevalence of use, awareness of the tobacco content and associated health risks of waterpipes among young adults in a non-university semi-rural underprivileged community in England.
A self-completed questionnaire was distributed by six schools and colleges to young adults aged 16–25 in Tameside, North West England.
A total of 210 young adults completed the survey, of these 12% smoked cigarettes and 16% smoked waterpipes. Of those that smoked waterpipes, 45% smoked at home and 88% smoked in shisha bars. Of the respondents, 62% did not know that shisha waterpipes contained tobacco and 18% believed that waterpipes were less harmful than smoking cigarettes. There was no difference in knowledge of tobacco content, or of the associated health risks, between those who smoked waterpipes and those that did not. The majority of respondents (81%) stated that if they wanted to know more about how shisha tobacco could affect their health they would access information via the internet. Social networking websites was by far the most popular route for communication for messages about the health risks associated with smoking shisha waterpipes.
These results suggest that waterpipes may have overtaken cigarettes as the method of choice for smoking tobacco among the young adult population in the UK.
Waterpipe smoking (also called hookah, shisha, narghile, hubble bubble) is popular among young adults across the globe. Over half of university students in Jordan1 and adolescents in Saudi Arabia2 smoke waterpipes. One in five American college students reported smoking waterpipes and believed that waterpipe smoking is less harmful than cigarettes3. A survey of UK university students found that 14% smoked waterpipes in the previous month4.
Relative to cigarette smoking, waterpipe use is associated with greater carbon monoxide, similar nicotine, and dramatically more smoke exposure5. Daily use of waterpipes produces a urinary cotinine level equivalent to smoking 10 cigarettes per day, and a single session of waterpipe use produces a urinary cotinine level equivalent to smoking two cigarettes in one day6.
In towns and cities across the UK, the number of shisha bars has increased dramatically in the past decade. In 2007 there were 179 shisha bars compared to 566 in 20127. The packets of favoured tobacco sold in shisha bars often carry no health warnings, in direct defiance of the UK Trading Standards regulations and the WHO advice that waterpipe tobacco should be subjected to the same regulation as cigarette and other tobacco products8.
Most of the reported data on waterpipe use in young adults has examined its use in cities and among university students. This report assessed waterpipe use in young adults in a semi-rural suburban town that contained no known shisha bars, although a large number of local shops and market stalls sell shisha paraphernalia and tobacco.
This survey aimed to measure the prevalence of waterpipe use, awareness of the tobacco content and associated health risks of waterpipes among young adults in Tameside in order to design an appropriate social marketing campaign targeted at this group.
A self-completion questionnaire was piloted with young adults before distribution to secondary schools and higher education colleges across Tameside. This resulted in the survey being shortened to the questions shown in Table 1 in an attempt to maximize uptake and completion.
Survey of young adults in Tameside; use and knowledge of shisha waterpipe tobacco smoking
Participant demographics Gender n (%) Age (years) n (%)
Female 104 (49.5%) 16–18 187 (89%)
Male 106 (50.5%) 19–24 20 (10%)
>25 3 (1%)
Do you smoke? Yes 43 (20%) Smoking methods Cigarettes 25
No 165 (79%) Waterpipes 33
Waterpipe venue At home 15
At shisha bar 29
Do shisha waterpipes contain tobacco? Yes 80 (38%)
No 54 (26%)
Don't know 76 (36%)
Is smoking a shisha pipe less harmful than smoking cigarettes? Yes 38 (18%)
Don't know 118 (56%)
If you wanted to know more about how shisha affects your health, where would you look? College 16 (8%)
Television Internet 14 (7%) 171 (81%)
Facebook 15 (7%)
Friends 27 (13%)
Other 16 (8%)
What is the best way to give you information about how shisha affects your health? Social networking sites 73 (35%)
Leaflets Posters 52 (25%) 50 (24%)
Text/BBM messages 41 (20%)
Information from college 40 (19%)
Pens 34 (16%)
Billboards 25 (12%)
Business card size info 16 (8%)
Screen savers 12 (6%)
Local newspaper 9 (4%)
Tameside is a semi-rural suburban area; poverty and unemployment levels are higher than average for England and the prevalence of cigarette smoking among adults is higher than the national average9. The targeted participants were people aged 16–25 years attending school or college. This included sixth form within school, sixth form college and higher education community college. The participating schools and colleges took the responsibility of conducting questionnaires with samples of young adults in their establishments. The paper questionnaire was distributed to students over the age of 16 years and completed independently and anonymously by the students.
The significance of the differences in responses between those that reported smoking waterpipes and those that did not was calculated using the z-test for the difference between two independent proportions.
The total number of eligible full-time students enrolled at the six participating schools and colleges was 2624. A total of 210 questionnaires were completed with a response rate of 8%. Males (106) and females (104) were equally represented among the respondents. The vast majority of respondents were aged 16–18 (133), with just 23 people over the age of 19 years participating (Table 1).
Survey responses
Survey responses are summarized in Table 1, and 20% of respondents identified themselves as smokers. Of the 43 self-reported smokers, 16 (37%) were female and 27 (63%) were male, while 30 were aged 16–18 years, 11 aged 19–24 years, and 2 were aged over 25 years. In all, 25 people (12%) reported that they smoked cigarettes and 33 (16%) reported smoking shisha waterpipes. Of those that smoked waterpipes, 15 (45%) smoked at home and 29 (88%) smoked in shisha bars.
Of the total respondents, 62% did not know that shisha waterpipes contained tobacco. Of those that smoked waterpipes, 18 (55%) knew that they were smoking tobacco, 10 (30%) reported that waterpipes did not contain tobacco and 5 (15%) did not know. A total of 177 of the respondents did not smoke waterpipes and of these, 62 (35%) stated that it contains tobacco (z-score=2.17, two-tailed p=0.03), 44 (25%) stated it did not contain tobacco (z-score=-0.58, two-tailed p=0.56) and 71 (40%) did not know (z-score=-2.75, two-tailed p=0.006). The young people who smoked waterpipes were significantly more likely to report that waterpipes contain tobacco, and significantly less likely to report that they did not know whether waterpipes contained tobacco, than those that did not smoke waterpipes.
When asked if smoking waterpipes was less harmful than smoking cigarettes, 18% of respondents reported that waterpipes are less harmful than smoking cigarettes, and 56% answered that they did not know. Of those who smoked waterpipes, 7 (21%) thought that waterpipes were less harmful than cigarettes, 12 (36%) thought they were not less harmful and 14 (42%) did not know. Of those who did not smoke waterpipes, 31 (18%) thought waterpipes were less harmful than cigarettes (z-score=0.51, two-tailed p=0.61), 42 (24%) thought they were not less harmful (z-score=1.52, two-tailed p=0.13) and 104 (59%) did not know (z-score=-1.74, two-tailed p=0.08). There was no statistically significant difference between those that smoked waterpipes and those that did not in their beliefs about whether or not waterpipes are less harmful than cigarettes.
The vast majority of respondents (81%) stated that if they wanted to know more about how shisha tobacco could affect their health they would access information via the internet.
Social networking websites was by far the most popular route for communication for messages about the health risks associated with smoking shisha waterpipes, with 35% of respondents preferring this route, compared to 25% preferring the next most popular route of leaflets.
This survey has demonstrated that the use of shisha waterpipes amongst young adults in a semi-rural, underprivileged area in North West England is similar to that in university students in large cities7. The proportion of young adults who reported using waterpipes (16%) was higher than the proportion who reported smoking cigarettes (12%), reflecting the trends found in other young adult populations, and suggesting that there is no difference in the popularity of waterpipes in the young adult university population compared with the non-university population. It has previously been reported that smoking waterpipes has become more common than smoking cigarettes among UK medical students10, and US university students11. This survey suggests that waterpipes may be replacing cigarettes as the method of choice for smoking tobacco among the young adult population in the UK.
Despite there being no known shisha bars in the study area, 88% of waterpipe users reported smoking in shisha bars. This suggests that either young people are travelling into neighbouring cities in order to visit shisha bars, or that illicit venues exist in the local town. These results suggest that the increased use of waterpipes by young adults cannot solely be attributed to the increased number of shisha bars in cities and large towns.
Most young people in this survey were unaware that shisha waterpipes contain tobacco; however those that smoked waterpipes had much greater awareness of the tobacco content than those that did not. There was no difference in this sample between those that smoked waterpipes and those that did not in their beliefs about whether or not waterpipes are less harmful than cigarettes. Previous work has identified widespread misconceptions about the tobacco content and health risks of smoking waterpipes, however we did not find, as Grekin and Ayna did among American students, that waterpipe smoking is more common among those that believe waterpipe smoking is less harmful than cigarette smoking3.
The preferred route for the communication of information about waterpipes and health in this sample was via internet social marketing. This has important implications for those working in public health who wish to raise awareness of the health risks associated with waterpipe use among young adults. It has been noted that local government and public health in the UK has been slow to respond to the increasing popularity of waterpipes as a means of tobacco use12. Traditional routes of communication, such as local newspaper articles, may not reach this group.
The number of both cigarette and waterpipe users identified might be underestimated by this survey due to respondents being unwilling to identify themselves as tobacco users in the school or college setting. This survey only included young adults engaged in education. A large proportion of young adults in Tameside are not engaged in education, and these results may therefore not be representative of the wider young adult population of Tameside.
This survey shows the low awareness of the tobacco content and of the associated health risks of waterpipes among young adults in an underprivileged area of England. Awareness needs to be raised about the tobacco content and associated health risks of waterpipe smoking through traditional and social media, so that young people can make fully informed decisions related to their health.
Go to reference
Khabour, O.F., Alzoubi, K.H., Eissenberg, T., et al. Waterpipe tobacco and cigarette smoking among university students in Jordan. The International Journal of Tuberculosis & Lung Disease. 2012;16(7):986-992. doi: 10.5588/ijtld.11.0764
Amin, T.T., Amr, M.A., Zaza, B.O., & Kaliyadan, F. Predictors of waterpipe smoking among secondary school adolescents in Al Hassa, Saudi Arabia. International Journal of Behavioral Medicine.2011;19(3): 324-335. doi: 10.1007/s12529-011-9169-2
Grekin, E.R., Ayna. D. Waterpipe smoking among college students in the United States: a review of the literature. Journal of American College Health.2012; 60(3): 244-249. doi:10.1080/07448481.2011.589419
Jawad, M., Abass, J., Hariri, A. et al. Waterpipe smoking: prevalence and attitudes among medical students in London. The International Journal of Tuberculosis & Lung Disease.2013;17(1):137-140. doi:10.5588/ijtld.12.0175
Jawad, M., Choaie, E., Brose, L., et al. Waterpipe Tobacco Use in the United Kingdom: A Cross-Sectional Study among University Students and Stop Smoking Practitioners. PLoS One2016;11(1): e0146799. doi:10.1371/journal.pone.0146799
Barnett, T.E., Smith, T., He, Y., Soule, E.K., Curbow, B.A., Tomar, S.L., McCarty, C. Evidence of emerging hookah use among university students: a cross-sectional comparison between hookah and cigarette use. BMC Public Health 2013;13(1):302. doi:10.1186/1471-2458-13-302
British Heart Foundation. Rise in 'shisha bars' prompts warning on dangers of waterpipe smoking. http://www.bhf.org.uk/default..... Accessed 23 August, 2013.
Eissenberg, T., Shihadeh, A. Waterpipe tobacco and cigarette smoking: direct comparison of toxicant exposure. American Journal of Preventive Medicine. 2009; 37(6):518-523. doi:10.1016/j.amepre.2009.07.014
Maziak, W. The waterpipe: an emerging global risk for cancer. Cancer Epidemiology.2013;37(1):1-4. doi:10.1016/j.canep.2012.10.013.
Neergaard, J., Singh, P., Job, J., Montgomery, S. Waterpipe smoking and nicotine exposure: a review of the current evidence. Nicotine & Tobacco Research 2007. 9(10): 987-994. doi:10.1080/14622200701591591
Public Health England . Tameside Health Profile 2017. http://fingertipsreports.phe.o.... Accessed 27 June, 2018.
WHO Study Group on Tobacco Product Regulation (TobReg). Waterpipe Tobacco Smoking: Health Effects, Research Needs and Recommended Actions by Regulators. World Health Organisation, Geneva, Switzerland (2005) ISBN 92 4 159385 7 .http://www.who.int/tobacco/glo... .Accessed 27 June, 2018.
CITATIONS (1):
Tobacco use among male inmates and their attitudes toward its prevention in Khartoum State: A cross-sectional study
Elhadi Awooda, Dina Shashati
Tobacco Prevention & Cessation
Tobacco use patterns and predictors among college students in Mangalore, South India: Findings from the Global Adult Tobacco Survey
Barriers and facilitators to cessation among tobacco users with concomitant mental illness attending group behavioral tobacco cessation: A qualitative study
Associations between Appalachian youth tobacco consumption and communication channel use
Tobacco use in Lao People's Democratic Republic: Results from the 2015 National Adult Tobacco Survey
INTRODUCTION METHODS RESULTS DISCUSSION CONCLUSIONS REFERENCES CITATIONS


I truly enjoyed EVERYTHING about this book. I have never written those words before. The story has a great twist at the end that I was not expecting. This is what I particularly loved. With so many characters, all with traits you can embrace and at the same time dislike, it was not easy to guess whodunnit. Magpie Murders is a must read, or in this case, listen. The narrators were both easy on the ears.
I love this series, but the narrator isn't right for Lexi. I'm sorry to say, its very difficult to listen to this narrator change Lexi's character into a shrill nag. I wouldn't put up with this tyrant in real life so why should I spend my leisure time enduring her vocal rants and raves, especially toward Slash. I don't think Slash's character would put up with it as well.
I don't like to post negative reviews, but it also sounds like the narrator just got new braces. I would really love to hear this series done by a really good narrator and include alot more about hacking! Sorry for the bad news.
Again, set the speed to .85 and you'll love it.
As in the previous book of this series, I set the speed to .85 and the narration was great. John Meagher really mastered the women's voices in this second book as opposed to the first. The series is fast and OMG, there was a twist I NEVER saw coming. I never would have even imagined it.
I loved the history and information about the Vatican. I had to go on Google so I could better see some of the places Rollins writes about. Fun.
I wish I could afford to travel the world and see all these places, but at least with series like these, Google images & Google EARTH, I can get a prety good picture. Thank you, James Rollins.
I really enjoyed this book after I set the speed down to .85. I don't know if the auther reads really fast or if the speed has been tampered with, but once it's set to .85 the narrator's s sounds aren't that noticible and he does a really good job. The women's voices were funny, but in the second book the narrator masters the ladies voices.
The plot had everything you could ask for in this type of genre. A fast pace with lots of twists and turns to keep you listening. Delightful writing created delightful characters.
When I agreed to stand by my best friend, Basia, on her big day, I had no idea what I was in for. Bouquets and unflattering evening wear I can handle. But between disgruntled dates, a beach venue, and suspicious packages, what else can go wrong? Oh, right - my parents don't know I've moved in with Slash. Oops? Thankfully, I've got everything semi under control, at least as far as Basia and Xavier know. They can leave for their honeymoon happy, knowing Elvis, Slash, and I will keep things safe at home.
Texas transplant Pru Parke has put down roots in England, but she never dreamed she'd live in a grand place such as Greenoak. When her former employers offer Pru and her new husband, former Detective Chief Inspector Christopher Pearse, the use of their 19th-century estate while they're away for a year, she jumps at the chance. Sweetening the deal is the prospect of further bonding with her long-lost brother, Simon, who happens to be Greenoak's head gardener. But the majestic manor has at least one skeleton in its closet.
As Always, Interesting! A Great Book!
On a new job, Pru gets to spend more time with her long, lost brother who is also a gardener. I loved the addition of a nephew, who really brings a light to the story.
I loved hearing the accents the narrator expertly performed. Listening to a narrator who has really taken the time to craft their art brings a lot of joy. I pulled up the Edinburgh Botanical Garden and Edinburgh in general to see the places the writer describes. It is awesome. Maybe someday I can go there. The internet expands the pleasure of an armchair traveler so much.
Pru Parke has her dream job: head gardener at an 18th-century manor house in Sussex. The landscape for Primrose House was laid out in 1806 by renowned designer Humphry Repton in one of his meticulously illustrated Red Books, and the new owners want Pru to restore the estate to its former glory - quickly, as they're planning to showcase it in less than a year at a summer party.
Good story. Too much on romance of main character.
This second book was a delight to listen to and now it feels as if Pru and Christopher are old friends. Pru is the head-gardener of quite a large project about an hour outside of London. I loved listening to the gardening ideas and her efforts and wished I could be in that garden too.
I was sad to see old Ned dead and gone, I quite liked the old fellow.
October in Cascade Springs means tourists are pouring in for the annual Food and Wine Festival, and Daisy hopes to draw those crowds to the store. She asks Violet and the local writing group, the Red Inkers, to give a reading of the works of Edgar Allan Poe on the shop's front porch to entertain the revelers. Everyone eagerly agrees. Yet their enthusiasm is soon extinguished when Violet discovers one of the writers dead in the shop moments before the event.
I never saw the ending coming, or who the killer turned out to be until the very last. Most of all, I loved listening as the characters in the town came to life through the great narration. The pictures painted for me were delicious and it was hard to see the book come to an end.
Listening to Crime and Poetry gave me many hours of pleasure. Amanda Flower knows just what her readers want and her series is fresh and lovely. The narrator is particularly gifted. I highly recommend this series. I can't wait to read the next book.


One of the biggest challenges facing bloggers with blogs that have been around for longer than a few months is to come up with fresh content on a regular basis.
Today your task in the 31 Days to Build a Better Blog challenge is to do an exercise that will identify a range of post ideas that you can use when stuck for an idea in future.
The key with this process is not to put yourself under pressure to come up with completely new and out of the blue ideas for every post you write. Instead – this process taps into what you've recently written on your blog and helps you to identify ways to extend those ideas.
The beauty of this is that you actually end up building a sense of momentum on your blog where your posts build upon and relate to what you've previously written rather than just writing a collection of posts that don't really build in any one direction.
Here's the mind mapping method that I've used (note: I've talked about this previously so it could be familiar to some).
The list could go on – really it is about finding ways to take ideas in a previous post and expanding upon and extended them.
For each idea draw a line out from the circle, draw a square (or use a different color) and write the idea inside of it.
From the example above you can see that I've come up with 15 ideas (not bad for 5 minutes of brainstorming) – some of them for multiple posts (series and ongoing weekly columns). Do it with more than one post and you will find that you'll often come up with more posts than you can actually use on your blog.
Your Task Today is to come up with a list of at least 10 future topics to write about. At this point your list should be not much more than the topic or title of your post. If you're feeling inspired you might like to choose one of them to begin to shape into an actual post – but don't feel you need to do that yet. Tomorrow we're going to take the list of topics and help you to take them to the next step by creating an editorial calendar for your next week of blogging.
I know that some bloggers doing the 31 Day challenge have very new blogs and perhaps don't have too many posts in their archives to base mind mapping upon. If this is you – you can take the same principle but instead of making your five starting circles previous posts – make them 'categories' that your blog might cover.
Update: Share your ideas and see how others are doing over at the forum post for the 31DBBB Day 11 Daily Task!
Semi backfiring on me, this task. Instead of blogging topics I'm getting ideas for my Newsletter.
I think the most important suggestion here from my perspective is keeping an eye on categories. If you think very clearly of your blog as a Web site on a given topic and then carefully choose sub-topics that break down your main topic, you can't go wrong. Come up with a handful of sub-topics from day one, sub-topics you want readers to be able to explore when they visit your blog. Soon you'll be on fire not worrying so much about what to write about next but what categories are under-represented and keep your blog from being as well-rounded as you want it to be. Sub-topics can also be broken down…and so on and so on. It becomes an obsession.
Thank you for this post it really helped me on getting my blog started. I was having trouble coming up with topics and took your ideas and they really got me going and sparked my creative side. My blog is on sports so their is plenty to talk about it was just coming up with some specific things to actually post.
This is a great exercise in planning. I find myself looking for inspiration to slap me across the face – and thankfully it has done so often in the two months that I've had my blog. But I know that won't sustain. Planning like this will be key to my success! Thanks for this tip.
ps. I've done one or two of these already – but not intentionally.
Love the 31DBBB challenge! Hadn't done mind mapping in a while, and used to do it with staff to brainstorm program ideas. Thanks for the reminder! And yes, I find that doing this away from the computer is often better. When doing this with staff I had everyone stand up (if they could) and timed it (five minutes) while writing down the ideas on a white board as fast as possible, then connecting concepts.
About writing slumps: for me coming up with ideas is easier than writing about them. One way I discipline myself is to light an incense stick and force myself to write until it's burned out. I've heard of others doing the same with a candle, or by writing while listening to a cd start to finish.
Thanks for presenting the nice facts and information.
As always i like your post.
I find it is best to sometimes plan out your blog posts ahead of time. Putting together an excel spreadsheet and planning out well in advance usually helps and triggering new ideas.
Although we'll get many post ideas, but is it Ok to stick to a single topic??
Mind Mapping is great way to push past barriers of writer's block.
My partner and I use iMindMap. You can do a lot of cool creative things with design and color which help feed those imagination muscles.
Good task for today. I'll be working on expanding what I have posted already. Very useful techniques.
We got a lot out of this task in terms of a lot of new fresh blogs to write about. I love it !
Great idea for coming up with new ideas for blog posts, I'll have to try this exercise.
I also keep a running list of topics that I want to cover; and I always keep it on me so that whenever an idea pops into my head I can jot in down immediately.
Thanks for the advice. It has certainly helped me with my new blog at http://www.blogs.chowjobs.com. 'Looking forward to reading more of your blog.
An interesting post and hopefully I shall never have to use your great advice.
From a personal point of view, because I'm actually writing about my quest for real life encounters, I'm hopeful that I shall never run out of experiences to write about.
Great technique for coming up with new posts! Never really thought of this one, but will start using it from now on!
I'm really surprised by how many ideas I came up with while doing this exercise. Some of them are not directly related to my previous posts, but just poped into my head while doing this. I had a small amount of things on my "Things to Blog About" list, but now I have 32 things on that list!
Some great ideas there. This is the best advice yet.
I like this exercise. Many years ago, I did a similiar exercise with my business to create many "legs" under my table. I'm sure this will give me a better directed approach to blogging.
I love this idea. I came up with ways to expand posts that I have made recently. Great to have a list to go to on days I don't have an idea.
Great idea. Now I'm finding that I have way too many ideas to write about :) THough, I do find that planning out the topics is kind of a 'recommended' roadmap for me when a better idea pops up during the week! Steno pad is my method of keeping track of the ideas.
I did the exercise for about 5-10 minutes and came up with twelve post ideas for my personal blog. I can only imagine how many other ideas I'll come up with for my other blogs!
hi Darren, seems I've been left behind so far. what a shame! but trust me, giving up will never show up in my dictionary, that's why I'm still here.
honest, I've always been excited reading EVERY post in this 31day plan, but it is this one that inspired me to comment, as you just read blogger's mind and find out what problems they are facing.
yes, topics running out is a problem for me, not serious but I could feel it sometimes. this brainstorming post is really great and helps a lot. I've had about 70 posts in my blog and try my best to update in daily basis. btw I have a fashion blog. surely I will do the homework today after my commenting here. but also, I will fulfill your suggestion on category exploration, I trust this will help me extend my coverage without ruining the Elevator Pitch I made.
On to the next task, thanks.
This works for me as I am a visual learner… charts and pictures agree with me. I have been facing some difficulties generating post ideas of late. Came to realise that while coming up with ideas are relatively simple as compared to crunching out content for a particular post.
Another thing you could do is to take 5 good posts on other blogs that you read, and turn them around, and come up with a few more ideas.


text:
Q: I can not start HTTP server Admin on AS400 The error message is...
 CPF9898 Escape 40 19/03/16 11:11:55.552230 QLWISVRA QSYS *STMT QLWIIHSMOD QHTTPSVR *STMT

 From module . . . . . . . . : QLWIMSG 5761SS1 V6R1M0 080215 Job Log MLCNAS05 19/03/16 11:11:55 Page 2

 Job name . . . . . . . . . . : ADMIN

 User . . . . . . : QTMHHTTP

 Number . . . . . . . . . . . : 022548

 Job description . . . . . . : QZHBHTTP

 Library . . . . . : QHTTPSVR

 MSGID TYPE SEV DATE TIME FROM PGM LIBRARY INST TO PGM LIBRARY INST

 From procedure . . . . . . : sendStartStopMessage__10LwiMessageFPcsN31

 Statement . . . . . . . . . : 55

 To module . . . . . . . . . : MOD_IBMLWI

 To procedure . . . . . . . : startLwiServer__FP10apr_pool_tP10lwi_conf_t

 Statement . . . . . . . . . : 105

 Message . . . . : INTEGRATED WEB APPLICATION SERVER Admin1 FAILED TO START. SERVER Admin1 NOT FOUND IN REGISTRY.

 Cause . . . . . : This message is used by application programs as a general escape message.

Where the Admin1 configure?
 How can I resolve it?

A: Any messages prior to that in the joblog?
You may want to look in the Apache log(s):
/QIBM/UserData/HTTPA/admin/logs/HTTPAdmin.log
/QIBM/UserData/HTTPA/admin/logs/error_log
More troubleshooting steps here


text:
← Taking the Long Road home – the Milltown Brothers interview
In from the rain again – doubling up with Inspiral Carpets and The Rainkings →
Looking Glass Girl by Cathy Cassidy – a writewyattuk review
In the year Lewis Carroll's Alice's Adventures in Wonderland turns 150, we can expect a number of events set around that influential work and all it led to.
Alice is a little too Marmite for some tastes, and I totally understand if a certain film or stage adaptation or past edition of the book itself put you off for life.
But there's no denying the impact Charles Lutwidge Dodgson's ground-breaking 1865 children's story made, inspiring generations of children and adults, including several authors.
You can add recent writewyattuk interviewee Cathy Cassidy to all three categories, the best-selling children's writer revisiting Carroll's tales again and again over the years.
So when she was asked by the team at Puffin to write her own Alice-themed children's book to help mark that big anniversary, she jumped at the chance …. or down the rabbit hole perhaps.
Despite that leap, in some respects Cathy is on solid ground with Looking Glass Girl, tackling some of the staples of her past success – issues like fitting in, bullying and peer pressure, friendship and first-love. There's even the odd foray into cake and chocolate. All part of CC's winning recipe for young fiction.
But here she gets to do all that in a slightly darker setting, immersing herself into that labyrinth of wrong turns Carroll carved out all those years before. Yet despite the potential pitfalls, she manages to come through the other side of the mirror (okay, that's enough throwaway Alice imagery now).
This is no clumsy retelling, Cathy instead crafting the story of modern-day Alice Beech as she tries to make her way through the maze of adolescence, in a book chock-full of Wonderland imagery.
Cathy's Alice is trying to come to terms with a change in the friends she got on so well with before high school, but who then dropped her like a stone to join the popular set.
Alice Spin: Cathy Cassidy has created her own twist on Carroll's classic (Photo: Louise Llewelyn)
She's also learning to stand on her own feet – waking up to her true self rather than just blindly fitting in, despite that reluctance to stand out from the crowd, something the majority of young readers can relate to.
Ms Beech's love of drama has helped, a passion that led to her landing the key part of her namesake in her previous school's Wonderland stage production.
That premise shouldn't put off those who feel Alice isn't for them though. And similarly it shouldn't put off those who love the book and feel this might be a watered-down or unfaithful take on it all. Because it isn't.
As we join the tale, our protagonist is unconscious and on her way to hospital after falling down stairs in suspect circumstances during an Alice-themed sleepover at 'queen of the school' Savannah's house.
What follows is something of a reconstruction of what happened that night, piecing together Alice's memory through flashbacks and Wonderland-related dream sequences as she battles back amid bedside vigils from family, friends and possible foes.
There's no cheap moralising, and even the less-palatable characters are believable. And while the coma gives the story a darker edge, it's no more sinister than the original text.
It appears effortless for all the carefully-constructed content, Cathy subtly inter-weaving various characters from the original text into her narrative, suggesting similarities between them and her own creations.
In the way the original stories are surreal and somewhat unsettling, there are elements of that too, not least the part-nightmare, part-fantasy world of Alice's dreamlike state.
Drink Me: A compelling book deserves an inviting cuppa (Photo: Cathrine Linden Sea)
As Alice looks to understand her classmates' motives, there's that sense of danger too, her fellow teens pushing the boundaries, not least through their modern twist on the original 'drink me' sequence and their secretive invite for a group of boys to this girls-only party.
Alice's blossoming relationship with Luke is also key, the lad who played the Mad Hatter in that school play still holding a candle for her, to the dismay of one of those old friends.
And throughout the coma sequences we get echoes of Carroll's tales, Alice – so au fait with the story – meeting the White Rabbit, the Duchess, the Lory, Tweedledum, Tweedledee, and many others who seem to hold the key to her memory.
All play a part in that potential unlocking, the White Queen's conundrum of living backwards or forwards just one dilemma translated to Alice's amnesia and a determination to unravel this mystery.
Meanwhile, the confusion brought on by her cerebral bleed fits perfectly with the Queen of Hearts' 'off with her head' command, Alice feverishly trying to comprehend exactly what happened to her and somehow get safely home.
In the same way that you can read Alice's Adventures in Wonderland and Through the Looking-Glass and What Alice Found There from a child's perspective and an older reader's point of view, you can do that here too.
Of course, I won't need to win over Cathy Cassidy fans. They've read enough to happily snap up anything with her name on it. All the same, Looking Glass Girl is a winning departure for her, and it's worth noting the author's respect for the original texts, doing Carroll's rich legacy justice.
Looking Glass Girl by Cathy Cassidy (Puffin) is available in hardback, paperback and e-book and audio formats from all good independent booksellers, online, and through various other sources, not least your local library.
For a recent in-depth interview with Cathy Cassidy on this blog, head here. And for more about the author, her past work and forthcoming book events and visits, try her website.
Meanwhile, check back on this blog shortly for a special feature marking the 150th anniversary of the original Macmillan publication of Lewis Carroll's Alice's Adventures in Wonderland.
About writewyattuk
A freelance writer and family man being swept along on a wave of advanced technology, but somehow clinging on to reality. It's only a matter of time ... A highly-motivated scribbler with a background in journalism, business and life itself. Away from the features, interviews and reviews you see here, I tackle novels, short stories, copywriting, ghost-writing, plus TV, radio and film scripts for adults and children. I'm also available for assignments and write/research for magazines, newspapers, press releases and webpages on a vast range of subjects. You can also follow me on Facebook via https://www.facebook.com/writewyattuk/ and on Twitter via @writewyattuk. Legally speaking, all content of this blog (unless otherwise stated) is the intellectual property of Malcolm Wyatt and may only be reproduced with permission.
View all posts by writewyattuk →
This entry was posted in Books Films, TV & Radio and tagged Alice in Wonderland, books, Cathy Cassidy, Charles Lutwidge Dodgson, Lewis Carroll, Libraries, looking Glass Girl, Macmillan, Puffin, young adult fiction. Bookmark the permalink.
6 Responses to Looking Glass Girl by Cathy Cassidy – a writewyattuk review
pagesbythesea says:
Insightful review of wonderful book. Thank you 🙂
Jackie Morris says:
I love the cover too by my lovely friend Erin Keen. Really want to get my hands on a copy of this.
Pingback: Rediscovering Alice's Wonderland – a 150th anniversary celebration | writewyattuk
loving the book so caputureing and for thats saying something because i persnolly do not like reading but i never wanta put this down. Great job.
writewyattuk says:
Glad you enjoyed it, Tamara. And this week we learned that Cathy's Looking Glass Girl has been nominated for the 2016 Carnegie Medal.
Pingback: Review | Looking Glass Girl by Cathy Cassidy – Peaceful Oblivion


Modullar non-return valve system which is fitted to drain tube of siphon opens automatically with flow of waste water and it provides discharge of waste water to sevvage system . In case of lapse of waste water, non-retum valve system closes auttomatically and it avoids overflovv of waste water, smell and insects which may come from sewage system. 2- Avoiding smell of water which drifted in siphon with bucket. 3- Double grid system which is on siphon provides on or off position of grid drains by means of grid lock hanle. Thus it provides effective protection system at case which place can not used for a long time.


As a patent attorney, Christine Cirl has special professional experience in drafting and managing German, European and international patent applications, drafting oppositions and nullity suits and preparing expertises, including extensive searches in relation to FTO expertises, IP landscaping and portfolio analyses.
Christine Cirl speaks German, English, French (basic skills) and Japanese (basic skills).
Studied Biology with focus on Technical Biology at Technical University (TU) Munich, Max-Planck Institute for Biochemistry, Munich, and at GSF (Helmholtz Center Munich, department: Gene vectors), specializing on Rational Protein Engineering; post-gradual studies and PhD (Dr. rer. nat.) and PostDoc at Institute for Medical Microbiology, Immunology and Hygiene, TU Munich; professional experience in the (re)insurance business (MunichRe and Allianz; areas: risk management, sustainability, due-diligence).
Legal training at an international law firm with accompanying legal studies at the Distance-Learning University of Hagen, at the German Patent and Trademark Office and the Federal Patent Court in Munich. Patent Attorney (Germany) since 2014, European Patent Attorney since 2015. At Eisenführ Speiser since 2015.


We're sure there was much rejoicing in heaven as our 2nd graders celebrated their First Reconciliation! Congratulations! May they always seek the forgiveness of our merciful God as they continue on their journey of faith!


text:
Identity theft still Asia's top concern
Misuse of personal information remains a key security concern in countries such as Singapore and Malaysia, reveals latest Unisys Security Index.
By Victoria Ho | December 11, 2007 -- 09:32 GMT (01:32 PST) | Topic: Tech & Work
update SINGAPORE--Identity theft remains at the top of Singaporeans' security concerns, according to a new study released Tuesday.
The fourth edition of the Unisys Security Index revealed that 83 percent of respondents are anxious about identity theft.
The survey polled 891 respondents, between the ages of 18 and 64, in Singapore to gauge its citizens' perception of security threats. The island-state scored 173 points, out of a possible 300, up slightly from 172 in September but down from the 188 index in May this year.
"The top two areas of concern for the past few surveys have been consistently identity theft and credit/debit card fraud," Scott Whyman, Asia South vice president and general manager at Unisys, said in an interview.
"In spite of healthy discussion and banks putting in tighter security measures, people still feel threatened regarding identity theft," said Whyman, adding that there were similar observations among other countries in the region, such as Malaysia and Hong Kong.
This is not necessarily a negative reflection on the region's security level, he said. "You need a high level of concern to instill changes. Being complacent is an insidious threat to security," he noted.
According to Whyman, health pandemics--at 72 percent--ranked third as a key security concern, though fear of terrorist attacks had been highlighted in this position based on previous releases of the Security Index.
Call for safer air transport
A new question added to this edition of the survey shed light on how Singaporeans felt about existing aviation security standards. Almost all responded favorably to having more done in terms airport security.
Some 96 percent of Singaporeans supported the implementation of one or more security measures at airports, such as consistent baggage screening and tracking. Another 97 percent said they would be personally prepared to undertake measures such as having luggage electronically tagged, providing biometric information and arriving earlier for extra security screening.
However, only 42 percent said they were willing to pay extra for tickets to cover the cost of extra security measures.
"This indicates a need for greater participation and cooperation between the government, commercial organizations and consumers," said David Chambers, Unisys partner of global transportation. He explained that there needs to be increased dialog and subsidies for such measures between the three parties, so that the burden of extra security may not be placed on only one group's shoulders.
"There needs to be a greater need for standardization among different airports and airlines, because security is only as strong as its weakest link," Chambers said.
Security Tech and Work
More from Victoria Ho
Intelligent Singapore
Singapore in 2013: Startups glisten, but broadband needs boost
IdeaSpace applications closing soon for SEA startups
Foreign startups in Silicon Valley still a rarity
TV-recording device gets on Indiegogo to launch in Singapore
EU's GPS satellites have been down for four days in mysterious outage
EU's Galileo global navigation satellite system nears 100 hours of downtime.
On Delta, facial recognition boarding doesn't sound optional
I listened as the gate agent tried to excite passengers about facial recognition boarding. He didn't mention they could opt out. This is how technology forces itself upon you. ...
Woz wants you to get off Facebook right now
The Apple co-founder believes the privacy tradeoff just isn't worth it.
What is a chief growth officer? Beats me
Many companies are now embracing the notion of a chief growth officer. But what is it? And why on Earth is it there?
Sport businesses become digital media companies in the digital media revolution
Another post by my favorite sports influencer and thought leader, Stephen Bourke. He charts the present and the future of an industry that has enormous impact: sports. ...
Facebook has a new way to make you love it. It's quite funny
How does one of the world's most suspicious companies think it can make progress? By getting help from those it used to decry.


text:
Driving tutor hit his pupil with a ruler
Home Folkestone News Article
Escape room plan given green light
By Sean Axtell
saxtell@thekmgroup.co.uk
Published: 15:50, 10 January 2018
An escape room will be the latest addition to Kent's growing array of unusual attractions.
A former car showroom at the Shakespeare Centre in Sandgate Road, Folkestone, will be developed into a room packed with puzzles and clues leading visitors to freedom against the clock.
Shepway District Council (SDC) this month gave the nod for unit two at the centre to be transformed into 168 sq m space, open seven days a week. Existing businesses at the centre will not be affected.
Shakespeare Centre - the new site for Kent's latest escape room
Breaking out across Europe since 2010, escape rooms typically involve physical puzzles and riddle games for guests to solve in small teams, in a series of games similar to the popular Channel 4 show Crystal Maze.
The applicant, listed as Mr Hart on SDC's planning portal, must abide by a series of conditions to get the scheme off the ground.
Development must begin within three years, and Mr Hart must comply entirely with the original blueprints and proposed opening times and ensure the premises isn't used for any other business.
It is unclear how many jobs will be created.
In his design and access statement, Mr Hart said: "The unit consists of the ground floor and basement areas. It is part of a five unit building with an office unit above.
"This property has a well-preserved front facade.
"The property was originally built as a vehicle showroom but was converted to five retail units and an above office space in 1984."
The latest development will be in direct competition with Escape60's exit room based in Town Walk.
Containing two rooms, within 60 minutes visitors must escape either a serial killer's lair or zombie apocalypse.
Since opening last year it has attracted positive reviews on the website TripAdvisor, scoring five out of five from 25 reviews.


American Samoans are the only people born on US soil but denied birthright citizenship.
Well, this is awkward. This month, five people from American Samoa—the only place in the world where babies born on US soil are denied US citizenship—argued in federal court that the government's refusal to grant them birthright citizenship violates the Constitution.
On the other side of the case is the Obama administration, which cited century-old Supreme Court decisions that spoke of "savage," "uncivilized," and "alien races"—and many legal scholars now see as outright racist—to justify continuing to deny citizenship to these US nationals.


Try this grain-free granola alternative next time you're itching for a classic snack. Start by preheating your oven to 300 F. Combine all the nuts, seeds, and coconut into a bowl and mix with melted coconut oil and honey. Once properly mixed, empty contents onto a rimmed cookie sheet and bake for 20 minutes. When the granola is lightly browned, remove from the oven and toss in dried cranberries. Once cooled you can enjoy this on-the-go snack at any point in your day. Just remember, while it is a healthy snack, it is quite energy dense. A little goes a long way with this one!
This recipe was taken from the minds at CookEatPaleo.


text:
Archive for the 'Business' Category
FDA guidance on the use of biomarkers as drug development tools
Back in September the US Food and Drug Administration announced that it was going to delay its publication of draft guidance on the qualification of drug development tools, originally promised for the summer. However, this draft guidance was finally published at the end of October. While still in draft form, the Guidance substantially expands on the outline of the pilot qualification process given in an article written by two members of the Center for Drug Evaluation and Research published in 2007.
The new guidance principally provides information on the proposed administrative process that will be followed by the FDA in order to qualify new drug development tools (DDTs). Qualification is defined as "a conclusion that within the stated context of use, the results of assessment with a DDT can be relied upon to have a specific interpretation and application in drug development and regulatory review." The document discusses two forms of DDT – biomarkers and patient-reported outcome scales. There are couple of points that bear discussion in relation to biomarkers.
Firstly, the new qualification procedure is aimed at enhancing the utility of a qualified biomarker across the industry. Hence, while previously use of a biomarker may have been part of an NDA, IND or BLA, this new programme is designed to make public those biomarkers that satisfy the qualification process, so that future drug development programmes can take advantage of already knowing that the biomarker has been qualified for a particular purpose. Of course, wherever a new biomarker is proprietary, it can be retained as such by not using the new qualification process, but by remaining part of the NDA, IND or BLA. This new programme, it seems therefore, is not particularly aimed at individual companies, but more towards collaborative groups that together can share the burden of the development of the drug development tools and submission to the FDA. Indeed, less than a month after the draft guidance was published, several major pharmaceutical companies and leading academic institutions announced such a collaborative biomarker consortium for COPD.
Secondly, while there is detailed information as to the administrative process, there is no information on the level of evidence required by the FDA to take a biomarker through from submission to qualification. There are a number of discreet stages that have to be undertaken, but nowhere are the criteria on which a new biomarker will be assessed described. The means by which such an assessment may be made are described: In the first stage they include a consultation process between the submitter and the FDA, and formal assessment of the biomarker follows, to include discussion at internal FDA meetings, discipline reviews and potentially even public discussions. However, the level of evidence required for success at each stage is not discussed.
It is tempting to suggest that this gap in the document is due primarily to the difficulty in formalising the criteria required for qualification of a biomarker. The wide range of uses to which biomarkers may be put, whether to preselect individuals for study or treatment, inform about disease progression, predict drug efficacy or toxicity or follow dynamically treatment in an individual, makes it difficult a priori to put together criteria that will apply in all cases. If this supposition is true, and each biomarker will be assessed on its own merits, with no reference to pre-determined criteria, the new qualification procedures do at least give the scientific community the ability to comment and provide feedback on decisions made, since all new qualifications will be published. Indeed the guidance states "Once a DDT is qualified for specific use, the context of use may become modified or expanded over time as additional data are collected, submitted, and analyzed. Alternatively, if the growing body of scientific evidence no longer supports the context of use, the DDT qualification may be withdrawn." Of concern, such scrutiny will not be applied to proprietary biomarkers submitted as part of INDs, NDAs or BLAs, but some scrutiny and sharing of validation study data is at least a move in the right direction. The FDA's qualification process seems likely to stimulate a further increase in the utility of biomarkers as drug discovery tools.
It should be noted that the Guidance Document is still in draft form. Published on October 25, the FDA is asking for comments and suggestions to be submitted to them by January 24, 2011 for consideration when preparing the final document.


Growing up immersed within the West Coast surfing culture, Shawn Stüssy first established his label by producing hand-shaped surfboards, embellished with a signature. The Tennis Polo Shirt is constructed from standard weight cotton and is cut in a regular fit. Finishing this red striped tee is a classic fold-down collar and branded logo on the chest.


text:
Q: UnsupportedOperationException in DSS server I am getting below exception when I try to connect DSS server to mssql 2008 r2. I have already added the sqljdbc4.jar file to wso2dss-3.0.1\repository\components\lib. Anyway still I am getting below error:
SEVERE: Java Runtime Environment (JRE) version 1.6 is not supported by this driver.
        Use the sqljdbc4.jar class library, which provides support for JDBC 4.0.
[2013-09-17 19:40:38,790] ERROR {org.apache.axis2.rpc.receivers.RPCMessageReceiver}
-  Java Runtime Environment (JRE) version 1.6 is not supported by this driver.
Use the sqljdbc4.jar class library,

A: sqljdbc4.jar class library requires JRE version to be 6.0 or later. So sqljdbc4.jar needs to be used when your java version is 1.6 or above. If your java version is 1.5 or less use sqljdbc.jar. You can download sqljdbc.jar here, http://www.java2s.com/Code/Jar/s/Downloadsqljdbcjar.htm


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Check out this article here if you'd like to learn more.
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