The Turner BioSystems TD-700 Laboratory Fluorometer in combination with Molecular Probes' RiboGreen™ RNA quantitation reagent provides a method for ultrasensitive quantitation of RNA in solution. Detecting and quantitating small amounts of RNA is extremely important for a wide variety of molecular biology procedures. These include measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot analysis, S1 nuclease assays, RNase protection assays, cDNA library preparation, reverse transcription PCR and differential display PCR.
The most commonly used technique for measuring nucleic acid concentration is the determination of absorbance at 260 nm (A260). The major disadvantages of the A260 method are the large relative contribution of proteins and free nucleotides to the signal, the inability to distinguish between DNA and RNA, the interference caused by contaminants commonly found in nucleic acid preparations, and the relative insensitivity of the assay (an A260 of 0.1 corresponds to a 4 µg/mL RNA solution). The use of fluorescent nucleic acid stains alleviates many of these problems.
The RiboGreen RNA quantitation assay implemented with the TD-700 Fluorometer can detect as little as 1 ng/mL RNA, (Figure 1) exceeding the sensitivity of ethidium bromide–based fluorometric assays(1) by 200-fold and A260 measurements by 1000-fold. The linear quantitation range extends over three orders of magnitude in RNA concentration, using two dye concentrations. Using one concentration of RiboGreen reagent and the recommended assay protocol, researchers can quantitate 20 ng/mL to 1 µg/mL RNA. By diluting the RiboGreen reagent 10-fold further, 1 ng/mL to 50 ng/mL RNA can be quantitated. Linearity is maintained in the presence of several compounds commonly found to contaminate nucleic acid preparations. Although the RiboGreen reagent also binds to DNA, pretreatment of mixed samples with DNase can be used to generate an RNA-selective assay.
Figure 1. High-range (A) and low-range (B) ribosomal RNA standard assays performed using RiboGreen RNA Quantitation Reagent and the TD-700 fluorometer. Separate instrument sensitivity calibrations were carried out for the two assay ranges.
TD-700 Fluorometer with standard PMT and 10 mm x 10 mm cuvette adaptor (P/N 7000-009).
Fluorescein filter kit (P/N 10-086R) which includes 486 nm excitation filter (P/N 034-0486) and 510-700nm emission filter (P/N 10-109R-C) and two Blue Mercury Vapor lamps (P/N 10-089).
RiboGreen RNA Quantitation Kit, supplied by Molecular Probes, Inc., Eugene, OR (catalog number R-11490). The kit contains 1 mL of RiboGreen RNA quantitation reagent stock solution in DMSO, 25 mL of 20X TE assay buffer (200 mM Tris-HCl, 20 mM EDTA, pH 7.5 in DEPC (diethylpyrocarbonate)–treated water) and 1 mL (supplied as 5 x 200 µL) of 100 µg/mL 16S and 23S ribosomal RNA standard (from E. coli), in TE buffer. The kit contents are sufficient for 200 high-range (20 ng/mL to 1 µg/mL) RNA assays using 2.0 mL samples in 10 mm x 10 mm cuvettes. RiboGreen RNA Quantitation Reagent (1 mL in DMSO) is also available from Molecular Probes as a separate item (catalog number R-11491). Handling, storage and the use of the reagents should be performed in accordance with the product information sheet supplied by Molecular Probes, Inc.
Two different dye concentrations are required to achieve the full linear dynamic range of the RiboGreen RNA quantitation assay. Different working solutions of RiboGreen reagent are prepared for the high-range assay (20 ng/mL to 1 µg/mL RNA) and the low-range assay (1 ng/mL to 50 ng/mL RNA), as described below in Section 3.3.
On the day of the experiment, prepare an aqueous working solution of the RiboGreen reagent by diluting an aliquot of the concentrated DMSO stock solution into 1X TE. If performing the high-range assay, dilute 200-fold. For example, to prepare enough working solution to assay 20 samples in 2 mL volumes, add 100 µL RiboGreen RNA quantitation reagent to 19.9 mL TE. If performing the low-range assay, dilute 2000-fold. For example, to prepare enough working solution to assay 20 samples in 2 mL volumes, add 10 µL RiboGreen RNA quantitation reagent to 20.0 mL TE. Prepare these solutions in sterile, disposable, polypropylene plasticware rather than glassware, as the reagent may adsorb to glass surfaces. Protect the working solutions from light by covering them with foil or placing them in the dark, as the RiboGreen reagent is susceptible to photodegradation. For best results, these solutions should be used within a few hours of their preparation.
Prepare a 2 µg/mL solution of RNA in TE using nuclease-free plasticware. Determine the RNA concentration on the basis of absorbance at 260 nm (A260) in a cuvette with a 1 cm pathlength; an A260 of 0.05 corresponds to 2 µg/mL RNA. The 16S and 23S ribosomal RNA standard, provided at 100 µg/mL in the RiboGreen RNA Quantitation Kit, can simply be diluted 50-fold in TE to make the 2 µg/mL working solution. For example, 40 µL of the RNA standard mixed with 1.96 mL of TE will be sufficient for the standard curve described below. It is sometimes preferable to prepare the standard curve with purified RNA similar to the type being assayed. In general, equivalent amounts of single-stranded RNA from different sources produce approximately equal fluorescence intensity readings. The assay remains linear in the presence of several compounds that commonly contaminate nucleic acid preparations, including nucleotides, salts, urea, ethanol, chloroform, detergents, proteins and agarose. However the fluorescence intensity may be affected (see Molecular Probes product information sheet MP11490 for details) and therefore the RNA solution used to prepare the standard curve should be treated the same way as the experimental samples and should contain similar levels of such compounds.
For the high-range standard curve, dilute the 2 µg/mL RNA solution into disposable cuvettes (or nuclease-free plastic test tubes for transfer to quartz cuvettes) as shown in Table 1. For the low-range standard curve, first dilute the 2 µg/mL RNA solution 20-fold with TE buffer to make a 100 ng/mL RNA stock solution and use this to prepare the dilutions shown in Table 2.
Table 1. Protocol for preparing high-range standard curve.
Table 2. Protocol for preparing low-range standard curve.
Add 1.0 mL of the appropriate aqueous working solution of RiboGreen reagent (prepared in Section 3.3) to each cuvette. The high-range working solution (200-fold dilution of stock) should only be used for performing the high-range assay and the low-range working solution (2000-fold dilution of stock) should only be used for performing the low-range assay. Mix well and incubate for 2 to 5 minutes at room temperature, protected from light.
Set-up the TD-700 fluorometer with a blue mercury vapor lamp (P/N 10-089), excitation filter 034-0486, and emission filter 10-109R-C. Calibrate the fluorometer in simple mode according to section VII of the TD-700 manual using the sample containing the highest concentration of RNA [Note A]. Measure the fluorescence of the remaining samples. To equalize any photobleaching effects, insert samples into the fluorometer for approximately equal time periods.
The fluorescence reading of the reagent blank (RiboGreen reagent + TE buffer only) may be subtracted from that of each sample. Corrected or uncorrected data may be used to generate a standard curve of fluorescence versus RNA concentration.
Dilute each experimental RNA solution in TE to a final volume of 1.0 mL in disposable cuvettes or test tubes. It may be useful to prepare several dilutions of each experimental sample. Large dilutions of the experimental sample may serve to diminish the interfering effect of certain contaminants. However, extremely small sample volumes should be avoided because they are difficult to pipet accurately. In addition, the level of assay contaminants should be kept as uniform as possible throughout an experiment, to minimize sample-to-sample signal variation. For example, if a series of RNA samples contain widely differing salt concentrations, they cannot be compared to a single standard curve. To avoid this problem, simply adjust the concentration of contaminants to be the same in all samples, if possible. See Section 3.6 for information on eliminating DNA from the sample.
Add 1.0 mL of the aqueous working solution of the RiboGreen reagent (prepared in Section 3.3) to each sample. Incubate for 2 to 5 minutes at room temperature, protected from light.
Measure the fluorescence of each sample using the same instrument calibration conditions as used to generate the standard curve (see 3.4.4). To equalize any photobleaching effects, insert samples into the fluorometer for approximately equal time periods.
If the standard curve has been constructed from background-subtracted data (see 3.4.5), subtract the reagent blank fluorescence reading from that of each of the samples.
Determine the RNA concentration of each sample from the standard curve generated in Section 3.4.
RiboGreen reagent also binds to DNA. Fluorescence in samples that is due to RiboGreen reagent binding to DNA can be eliminated by pre-treating the sample with RNase-free DNase, ensuring that the entire sample fluorescence is due to dye bound to RNA.
Prepare 10X DNase digestion buffer: nuclease-free 200 mM Tris-HCl, pH 7.5, containing 100 mM MgCl2 and 20 mM CaCl2.
Add 0.11 sample volume of 10X DNase digestion buffer to each DNA-containing sample (for example, to a 9 mL sample, add 1 mL 10X buffer).
Add about 5 units of RNase-free DNase I per mg of DNA thought to be in the sample.
Incubate the sample at 37°C for 90 minutes.
Dilute the sample at least 10-fold into TE to diminish effects of the digestion buffer salts on the RiboGreen assay procedure.
Perform the RiboGreen assay as described above.
[A]. For optimal detection sensitivity, separate calibrations should be carried out for the high range and low range assays.
2. Sambrook, J., Fritsch, E.F. and Maniatis, T., Molecular Cloning: A Laboratory Manual, Second Edition, Cold Spring Harbor Laboratory Press (1989).
RiboGreen is a trademark of Molecular Probes, Inc. RiboGreen RNA Quantitation Reagent is covered by current or pending U.S. and foreign patents.


The UFC today announced that American Charles Rosa will step in, with just a week's notice, to face Dennis Siver at UFC Fight Night Stockholm presented by Unibet.
The change comes following a ruling by the Swedish Mixed Martial Arts Federation regarding Taylor Lapilus, who was due to fight Siver on 4 October.
The Swedish Mixed Martial Arts Federation ruled that Lapilus, fighting out of Paris France, was not a suitable opponent for Siver.


(1888PressRelease) October 22, 2018 - Hong Kong-based LiDAR pioneer, Data Control Technitic is set to partner with a commercial drone manufacturer wishing to tap interest among consumers for enhanced 3D mapping functionality. The commercial drone market has ballooned in recent years thanks to strong uptake among enthusiasts keen to enjoy the versatility of the highly maneuverable gadgets.
Data Control Technitic recently said that it was looking to diversify into sectors and industries outside the key driverless automotive space. It says it has been approached by a well-known Hong Kong-based drone maker keen to bolster the LiDAR sensing and mapping capabilities of its premium products.
"We were somewhat surprised when they made initial overtures," explained Data Control Technitic's Chief Technology Officer.
Drone technology has progressed significantly since first variants emerged on the consumer market. With flimsy, plastic models being supplanted by hi-tech, carbon fiber-bodied models controlled by sophisticated modules, demand has increased for better mapping technology as well as higher definition cameras.
The drone manufacturer has not been named because, according to Data Control Technitic, it has an existing arrangement with a supplier that it does not wish to alert to the fact that it is approaching alternative partners.
"We'll be working closely with them to construct a carbon fiber housing for our LiDAR sensor in a bid to reduce weight since the heat resistance capabilities of the housings used in our automotive installations won't be required for flight," said the Data Control Technitic Chief Technology Officer.


text:
Q: How to check if a single letter (which has been input as a string variable) is equal to any character in another string? I am trying to make a hangman game at the minute and this is the code so far:
word = raw_input("Please enter a word")

correctguesses = []
wrongguesses = []

guesscorrect = False

while guesscorrect == False:
    guess = raw_input("Guess a letter")
    if len(guess) != 1:
        print "Your guess was more than one letter"
    for i in word:
        if guess == i in word:
            print "correct"
            correctguesses.append(guess)
    print "here are your correct guesses so far" ,(''.join(correctguesses))
    for i in word:
        if guess != i in word:
            print "incorrect"
            wrongguesses.append(guess)
    print "here are your wrong guesses so far:", (''.join(wrongguesses))

my output:
correct/
here are your correct guesses so far:/ e/
incorrect/
incorrect/
incorrect/
incorrect/
here are your wrong guesses so far:/ eeee/

It is doing that because it isn't the correct letter for the 4 other letters in hello (which was the word).

A: word = raw_input("Please enter a word")

correctguesses = []
wrongguesses = []

guesscorrect = False

while guesscorrect == False:
    guess = raw_input("Guess a letter")
    if len(guess) != 1:
        print "Your guess was more than one letter"
        continue #to prompt for input again
    for i in word:
        if guess == i: #i will be a letter in the word
            print "correct"
            correctguesses.append(guess)
    print "here are your correct guesses so far" ,(''.join(correctguesses))

    for i in word:
        if guess != i: #put this case in the else block of the if in the previous loop and remove this loop
            print "incorrect"
            wrongguesses.append(guess)
    print "here are your wrong guesses so far:", (''.join(wrongguesses))

I have commented some of the details.
This course might help with basics of python and programming.

redpajama_set_name: RedPajamaStackExchange


Mortgage Refinancing in Vaughan, Ontario Made Easy!
I'm Lucia Gugliuzzi and I'm an experienced Mortgage Broker working in Vaughan and the surrounding areas. Let me help make this the start of a new financial life for you and your family. We'd love to help you crunch some numbers to see what kind of life you could be living. Talk to us about scheduling a free, no-obligation review of your situation. We guarantee you'll be glad you did.
Lower your debt, boost your monthly cash flow, access equity in your home and be mortgage-free quicker!
Certain life stages or financial plans may require that you access the equity that you've built up in your home. This is where refinancing your mortgage allows you to take advantage of the equity in your home and direct it to other priorities including: Debt Consolidation, Financing home renovations, Freeing up funds for investment situations, supporting children's post-secondary education and more.
Make this the start of a new financial life. We'd love to help you crunch some numbers to see what kind of life you could be living! Talk to us about scheduling a free, no-obligation review of your situation. We guarantee you'll be glad you did..
What is Mortgage Refinancing and How Does It Work?
When it comes to planning for your future, your mortgage will play a big part in your life decisions, therefore one of the options on hand for you to explore is mortgage refinancing in Vaughan. You might have heard about it from family and friends and how they have leveraged their mortgage to control their household finance better. They could all be commended for the solutions they have shared because it has helped not only improving the cash flow but also managed finances better with less stress.
They couldn't have explained it any better! Mortgage refinance options in Vaughan give you the chance to be in control of your finances. There are a lot of times where debt and financial obligations have pushed you to the back seat. You were just worried every month not knowing what to expect next, which added to your financial stress and anxiety. Attention is to be given to one's budget when purchasing a home or getting into debt. Let's explore further…..
In Canada, for example, homeowners cannot refinance over 80% of the home value. This rule was implemented to avoid overspending and helping the homeowner with maintaining the equity.
Unfortunately, sometimes circumstances change and unexpected situations may come up. People resort to credit cards and sometimes those become unmanageable.
If this is your first time in considering mortgage refinance in Vaughan or even if you are from other areas, I can help and guide you through the process. Take a look at what one of my previous clients have to say about my services.
Mortgage refinancing can be quite tricky for homeowners simply because of the process, time, and the specialization it takes to get the job well done. A lot of experts might give you the idea that it is all about interest rates. As much as this is an integral part of the decision making process on your end, I also underscore the importance of cash flow and easiness in money management.
When you talk about refinancing, it may also referred to as breaking your mortgage contract early. This is because when you undertook the mortgage loan, you entered into a contract with your lender which you agreed to honor up until the time of the expiry of the mortgage term. If you want to amend or even get out of that contract, essentially you are breaking away from that agreement.
Before we go into the details of what a mortgage refinance loan is all about, you need to understand that a mortgage loan is not a one-size-fits-all type of agreement. Simply put, a mortgage loan is a highly customizable solution depending on your needs and present financial situation. This means that the mortgage loan should be able to fit your finances and should be tailored to your particular situation.
When you are refinancing, in essence you taking out a new mortgage. Given the mortgage refinance options and available, you may have the option of a variable or a fixed rate mortgage. Consideration is to be given to the length of repayment, and to some extent to the interest rate. At this point, you already know that buying a house is quite a big investment. It might even be one of the biggest purchases of your life. This further underscores the importance of doing it the right way while keeping in mind the household expenses and obligations.
You might be wondering at this point why you need to refinance your loan when you already have so much leeway at the very beginning. The ability to decide on so many important mortgage factors is at the beginning. It is important to work with an experienced mortgage brpler that will go beyond the call of duty and guide you through your finances and options. This should give you the peace of mind to see it through until the end. However, change is inevitable and mortgage situations can change.
When you originally took out the mortgage, you needed to keep in mind that your needs could widely change in the coming months or years. These could be from family situations to a professional career. All these can make you rethink your financial decisions from the past including your mortgage loan. This is why mortgage refinancing in Vaughan sometimes becomes an option.
When refinancing your mortgage, you need to keep in mind that you are not limited to working with your current lender. You have the option of bringing your business elsewhere especially if your needs will give you a better service with a new lender. I always recommend that you work with a mortgage broker that is well connected because we have the resources available under one roof from which you may benefit. I make it a point to connect with the correct channels so that we can help with the circumstances.
There are a number of debt relief programs out there at present. This is simply because people are looking for ways to manage their financial obligations. Debt consolidation is one of the more popular options you can look into and mortgage refinancing gives you that opportunity to consolidate your debt obligations. Refinancing your mortgage to consolidate your debts under one account will work best if you have enough equity in your home. This way, you are not adding to your debt payments but simply "borrowing" from your home equity.
Whichever way you look at, breaking your mortgage contract because you can get a lower interest rate will save you money down the road. This happens when the housing market and even the economy is doing good while resulting in lower interest rates. It is not uncommon for homeowners to choose mortgage refinance in Vaughan and to take advantage of it. Keep in mind that saving on interest rates will mean more money in your pocket.
There will be times when you might come across an investment opportunity that you feel will pay off in the long run. When this happens, refinancing your mortgage might just give you that extra funds you need to take advantage of that investment opportunity. You may not want to miss on the opportunity, therefore exploring mortgage refinancing could be the best option. I always say "make your mortgage for you, don't work for your mortgage".
If you have children who are about to start college, one of the worries you may have is the cost. High tuition fees in some colleges and universities are no joke. It will cost tens of thousands of dollars to support post-secondary education. This is one of the reasons why many parents take opt for mortgage refinancing – to help their older children manage their college studies and other expenses.
Financial education assistance in Canada has become harder and harder to obtain, therefore mortgage refinancing may be the only option.
Your house will need home improvements over time and the only thing you can do about it is to be proactive and attend to repairs as soon as possible. You do this because you either love your house or you want to sell it in the future. Whatever the reason is, improvements can become costly especially if you did not include it in your household budget. This is where refinancing can help you get the needed cash to help you get those home repairs and maintenance under way.
Sometimes people like to take equity out of their home for reasons either than debt refinance. They may want to go on vacation or make investments or simply help their family. The home owner may revert to this option for any of the reasons above. In some cases, seniors or the silver generation, may want to use the property for their enjoyment, help their family or simply have the cash available for other reasons.
The "rate" refers to the interest rate you pay, while "term" refers to the period of time the financing agreement covers. Most terms available are: 6 month, 1,2,3,4,5 year terms, and the interest rates will be fixed for whatever term one chooses.
That being said, rate-and-term refinancing loan means you will be making some adjustments on either your interest rate, your repayment term or even both. This means that if you are at a 15-year mortgage amortization you can refinance for a term available and desired.
There may be circumstances where you may not qualify for a mortgage refinance with with a traditional lender, better yet, with one of the chartered banks. This is where we come in and arrange alternative lending solutions. This would be a short term solution to give you time to work on rebuilding and re-establishing you credit. A strong discipline has to be implemented as alternative lending can be rather expensive. I recommend to Follow my guidance so you can accomplish your goal, that is very important. This is where I think commitment is necessary.
Much like when you took out your mortgage in the past, mortgage refinancing will entail closing costs and other fees. Here are some of the mortgage refinancing fees to keep in mind.
Mortgage prepayment penalty – This is when you refinance the whole mortgage entirely.
You can have other options either than refinancing the whole mortgage. Some home owners may choose to take out a line of credit, a secured visa or a private second mortgage. However, there may be some restrictions.
When you choose to break your mortgage earlier than your payoff date, it will come with a penalty. The penalty will differ depending on whether you have a fixed-rate or a variable rate mortgage as well as the bank that holds your mortgage . For a variable-rate mortgage, usually the penalty is three months interest payments or the interest rate differential (IRD), whichever is higher. The IRD is computed based on the interest rate offered prior to being discounted. Some banks will charge based on the pre-discounted rates and some others based on the contract rate. We are always very cautious in relying this because every bank has different guidelines and not always understood by the consumer. This is why it is important to discuss it with your mortgage broker. You will get a better understanding from the beginning, this is why it is worth to talk to a professional to walk you through. After all, it is important to be prepared earlier than finding out when it's too late. At that point, you may not have the options that you need to resolve your problem.
Whether you are working with the same or with a different lender, this fee always applies when restructuring your mortgage. If your mortgage refinance means switching to a different lender, you need to pay for the discharge fee, usually this is all included in the closing costs. The amount differs from every bank or province and lender, but the average is anywhere between $300 to $400. This is subject to change depending on the lender.
It is to be noted however, that some banks will cover the cost and may offer a special perk.
Regardless of whether you are working with a new lender or refinancing with your current one, you need to pay this fee, this is considered part of the legal cost. This is the process where the lender assigns a new mortgage amount on the title of your property. The amount is dictated by the provincial government but it is usually about $70 and up.
You could also consult a real estate lawyer who will handle documents review. I can also direct you to review your new terms and conditions and get you to get clarification by the lawyer undertaking the transaction.. Take a look at what one of my previous clients mentioned about my services.
This basically refers to the market in your areas since you are refinancing to have better payment options. Timing is crucial in your mortgage refinance plans. I can help you understand the market and we can identify if current rates are beneficial for you. Take a look at one of my previous clients.
Do you remember the first time you took out a mortgage? If so, the documents needed would be quite similar. You might remember that these includes pay stubs as well as tax documents, in a nutshell, proof of income. Having the correct and current proof of income is a crucial component in the quality and speed of the transaction.
Proof of income in the form of T4's and Notice of Assessment or NOA. Your NOA is a statement sent out by the Canada Revenue Agency detailing income and taxes paid.
Proof of employment in the form of an employment letter from your current job as well as pay stubs.
Secure a copy of your mortgage statement showing your balance as well as the terms of your loan.
Be aware of your credit score as well as your current assets and debt obligations.
Self-employed individuals will also need proof of self-employment. The length of this will depend on the type of lender funding the transaction.
The idea of a mortgage refinance process is to help you gain a better financial advantage by using your home's equity. It might seem to be a simple enough process but it can start to get overwhelming especially when you dive into the whole process. This is where I can come in and help you from start to finish while taking the stress and pressure off. Let me leave you with a testimonial from one of the people I have had the honor or helping for over a decade.


text:
// Copyright (c) 2009-2012, Andre Caron (andre.l.caron@gmail.com)
// All rights reserved.
//
// Redistribution and use in source and binary forms, with or without
// modification, are permitted provided that the following conditions are
// met:
//
//  * Redistributions of source code must retain the above copyright
//    notice, this list of conditions and the following disclaimer.
//
//  * Redistributions in binary form must reproduce the above copyright
//    notice, this list of conditions and the following disclaimer in the
//    documentation and/or other materials provided with the distribution.
//
// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS
// "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT
// LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR
// A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT
// HOLDER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL,
// SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT
// LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE,
// DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY
// THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
// (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
// OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

/*!
 * @file w32.io/StandardOutput.cpp
 * @author Andre Caron (andre.l.caron@gmail.com)
 */

#include <w32.io/StandardOutput.hpp>
#include <w32/Error.hpp>

namespace {

    ::HANDLE get ()
    {
        const ::HANDLE handle = ::GetStdHandle(STD_OUTPUT_HANDLE);
        if ( handle == INVALID_HANDLE_VALUE )
        {
            const ::DWORD error = ::GetLastError();
            UNCHECKED_WIN32C_ERROR(GetStdHandle, error);
        }
        return (handle);
    }

    ::HANDLE set ( ::HANDLE replacement )
    {
        const ::HANDLE current = get();
        if ( ::SetStdHandle(STD_OUTPUT_HANDLE,replacement) == FALSE )
        {
            const ::DWORD error = ::GetLastError();
            UNCHECKED_WIN32C_ERROR(SetStdHandle, error);
        }
        return (current);
    }

}

namespace w32 { namespace io {

    StandardOutput::Redirection::Redirection ( OutputStream& output )
        : myPredecessor(set(output.handle()))
    {
    }

    StandardOutput::Redirection::~Redirection ()
    {
        set(myPredecessor);
    }

    StandardOutput::StandardOutput ()
        : OutputStream(Object::claim(::get()))
    {
    }

} }

redpajama_set_name: RedPajamaGithub


text:
Trump makes 15 new friends in Davos, three of Indian originhttps://indianexpress.com/article/world/us-president-trump-new-friends-davos-indian-origin-wef-switzerland-5040661/
Trump makes 15 new friends in Davos, three of Indian origin
Trump, who arrived here Thursday afternoon, told Schwab -- who on his part said the US President's strong leadership is open to misconceptions and biased interpretations -- that he has made "15 new friends" here in Davos.
By PTI |Davos | Updated: January 26, 2018 11:59:04 pm
A chilling letter by a billionaire warning against 'business as usual' has Davos chattering
WEF: Donald Trump takes his America First policies to Davos globalists
DAVOS : U.S. President, Donald Trump, left, shakes hands with German Klaus Schwab, Founder and Executive Chairman of the World Economic Forum, WEF on the last day of the annual meeting of the World Economic Forum, WEF, in Davos, Switzerland, Friday. (AP/PTI)
US President Donald Trump on Friday declared before a full house at Davos that he has made "15 new friends" whom he did not know before at a dinner last night — including three of Indian origin. After a 'band' welcome and a nearly 20-minute speech, Trump sat down for a brief question and answers session with WEF Founder Klaus Schwab on the last day of the annual pow-wow of rich and powerful from across the 'fractured' world and began by complementing him for putting together this "really great" economic forum, reports PTI.
Trump, who arrived here Thursday afternoon, told Schwab — who on his part said the US President's strong leadership is open to misconceptions and biased interpretations — that he has made "15 new friends" here in Davos. "We had dinner last night with about 15 leaders of industry — none of whom I knew, but all of whom I have read about for years — and it was truly an incredible group," Trump said.
"And I think I have 15 new friends. So this has been really great what you have done in putting it together, the economic forum," he said. These 15 industry leaders from Europe — whom Trump described as "very powerful businesspeople of the world" and asked them to introduce themselves one by one and say a few words at the dinner table, as per a White House release —included Swiss pharma giant Novartis' incoming CEO Vas Narasimhan, Nokia CEO Rajeev Suri and Deloitte CEO Punit Renjen.
Others were heads of Bayer, Anheuser-Busch InBev, Siemens, AB Volvo, SAP, Adidas, Statoil, Nestle, ABB and HSBC. At the dinner, Renjen said, "Mr President, thank you for having me. Punit Renjen from Deloitte. On behalf of 265,000 employees across the globe, 70,000 in the US, thank you again for having us".
As per the White House release, Trump replied, "Great company. Thank you very much. Great job." Suri said Nokia runs the world's second largest telecom network and has 15,000 people in the US and one of its strongest R&D setups in the world is spread throughout the US.
He further said, "We have half of the acquisition of Alcatel-Lucent. We own Nokia Bell Labs, which is in New Jersey. We do a lot of stuff in the West Coast, in Chicago, and throughout the country, really. So just under half of our people do research and development, and the rest are doing services and 4G networks and 5G. So I'm very happy and pleased with your infrastructure focus…"
Narasimhan said Novartis is one of the largest health care companies in the world and its focus is on innovative medicines, generics, as well as eye care. He elaborated that Novartis has about 22,000 employees in the US across 21 sites and invests about USD 14 billion every year in the US, including USD 3.5 billion in research.
Further, he described US as one of the key markets and also key places where it drives innovation. "And we are really pleased with the tax reform, but also very pleased with the great progress being made at FDA. We believe you have a great leadership team there and they are doing all the right things to accelerate innovation," he said.
Best Of Express
Trump replied, "Scott is great, and Alex is great. You know, Alex is just starting, and he's highly respected. So that's fantastic. Scott Gottlieb, as you know, is a star," referring to his FDA Commissioner and Health and Human Services Secretary, respectively. Narasimhan said further, "He (Scott) is a star. And I think his vision for tobacco and trying to improve — reduce the use of tobacco around the world is also very inspiring."
After everyone's introduction, Trump said, "I want to thank everybody. Really, you have done incredible work, incredible jobs. These are some of the great companies of the world, many of the great companies of the world".
1 Algerian army kills eight armed men in Khenchela province -ministry
2 China's development push in poor countries worries non-profits
3 Will ensure Afghanistan never again becomes terrorists' safe haven: Donald Trump

redpajama_set_name: RedPajamaCommonCrawl


I'm a nanny because I love kids, I am and early childhood education major. I enjoy the energy that they have along with the bright imagination that comes with them. I enjoy being around kids, it would be my ideal job for my 7 week winter break, along with my summer break.
My past childcare experience I am currently a nanny 3 days a week for two boys, ages 5 and 7. During the summer I prepared all three meals for them and took them to activities. Now that school is in I take them to and from school. And make them breakfast and dinner and pack their lunch. During the summer I also prepared crafts for them to do and took them to the park and library. I have been babysitting since at least 7th grade. I have cared for a family of 4 with children ages; 1,3,7,10. I have also watched infants and I have also cared for 2 children ages 4 and 6. The most experience I have would be due to my 3 year old brother, who I have cared for and helped every step of the way. I have cared for all ages of kids and at all different levels of care taking.


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Japan's rural charm comes alive in this traditional alpine village
By JSG Staff | July 30, 2021 | No Comments | Postcards from the Jet Set Generation Blog
With Olympic coverage shining a spotlight on Tokyo, Japan's dynamic urban beauty is on full display. Far from the noise and excitement of the city, Japan's rural countryside holds oft-missed beauty of a different kind to match its metropolitan counterparts. Japan's rural areas provide a glimpse of the past, a preserved picture of classic Japanese Architecture in the shadow of ancient forests and frosted mountains.
You don't need to journey as far north as snowy Hokkaido, with its world-famous skiing, to experience the splendour of rural Japan. 3.5 hours west of Tokyo by train, tucked away in the mountains of the landlocked prefecture of Gifu, you'll find the historic village of Shirakawa-go, stunning in its unspoiled, traditional beauty. Originally established specifically for its remoteness, Shirakawa-go, untouched by time, enables visitors to unplug into the quiet calm of daily life from a bygone era. Composed of roughly 100 thatched roof Japanese gassho-zukuri farmhouses, Shirakawa-go offers guests rustic shelter from the snows of winter and the heat of summer. The largest village, Ogimachi, is flush with sightseeing opportunities and museums, and acts as the perfect staging point for venturing into the alpine valley beyond.
Recognized as a UNESCO world heritage site, an overnight or multi-night stay at one of Shirakawa-go's fairytale farmhouses is the perfect way to experience Japan's humble roots, and get far, far away from the concerns and worries of a post-COVID world. Warm yourself by a roaring farmhouse fire in the cool nights and enjoy traditional Japanese countryside comforts at a picturesque village from another era.
For more information on Shirakawa-go, visit https://www.japan.travel/experiences-in-japan/en/2879/.
Source: Japan National Tourism Organization
Tagged Asia, Japan
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The view from the Menjangan Dynasty Resort, Beach Camp and Dive Centre in Northwestern Bali, Indonesia.
A glamourous camping resort will open in Northwestern Bali in mid-August 2016. It is located on an isolated peninsula, which is surrounded on three sides by ocean and a calm lagoon.
The Menjangan Dynasty Resort, Beach Camp and Dive Centre will offer a glamorous camping, a.k.a. "glamping", experience.
The resort is set amid 16 hectares and has views of the ocean, Menjagan Island, aNational Park, and three mountains on nearby Java: Mount Raung, Mount Ijen, and Mount Baluran.
The resort has 24 beach camp tents as well as, two one-bedroom and two two-bedroom cliff tent villas, which are African Safari tents imported from South Africa.
Tents have all of the amenities you would expect at a five-star resort. Tent villas have private infinity pools.
Facilities include a 158-square-metre infinity swimming pool, a beach club and bar, a dive centre, a spa with private waterfront spa rooms, an exercise room, and a space for weddings, events, or retreats.
There is a white sandy beach. A buggy services transports hotel guests around the property.
Northwestern Bali is off the well-trod tourism track of Jimabaran Bay, Kuta, Nusa Dua, Seminyak, and Ubud. It offers visitors a chance to chill out in a pristine environment.
Bali tourist attractions can be crowded. For ecotourists and active travelers, this is is one of the best places to visit in Bali.
Activities in this part of Bali include diving, snorkeling, trekking, cycling, and horseback riding. There are hot springs, waterfalls, a pearl farm, and a quiet village nearby.
Menjangan Dynasty Resort is the sixth property to be managed by Prime Plaza Hotels and Resorts in Bali and its eleventh property in Indonesia.
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text:
Le tepuy Tramen est un des tepuys du Venezuela, jusqu'en 1978 il a été confondu avec le tepuy Ilú car la vallée les séparant était inconnue.

Voir aussi
 Tepuy

Sommet au Venezuela
Tepuy
État de Bolívar

redpajama_set_name: RedPajamaWikipedia


Climatologist Richard Alley, an NAS member and professor of geosciences at Penn State, mentioned on CNN what is inflicting the file-low temperatures within the United States and Canada. In August 1948, Lysenko gave a public handle to the Lenin Academy of Agricultural Sciences.
Evaluation of historic information means that science, on many events has proved to be a curse for humanity moderately than a blessing. We work closely with the scientific neighborhood to assist transformative applied sciences to empower and advance all of science. A compulsory mission encourages students to appreciate the environmental, social and ethical implications of science. PNAS February 5, 2019 116 (6) 1940-1945; revealed ahead of print February 5, 2019.


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Children nowadays live in a media-rich environment, which can make parenting a daunting task. This inaugural lecture discusses three aspects of parental mediation of children's media use.
First, a sketch of the media saturated world of children is presented, because that is the media situation parents have to act on. It is concluded that, although several surveys on children's media use in Europe exist, none of them gives a complete overview of the media ownership and use by children from early infancy until early adolescence. Therefore, a new media monitor is proposed.
Next, the research on parental mediation is reviewed. It is argued that despite the many studies done so far, we still have little knowledge on how and when parents guide their children when using the media. Especially studies on the effectiveness of parental mediation, and on the mediation of children that are more at risk and that are very young are lacking.
Finally, it is argued that parents are in need of formal and informal forms of parenting support, which they can get from various sources. The information given by institutional sources with regard to parental mediation, however, in the Netherlands often is not validated or evidence-based, because the professionals are not yet well informed about children, media, and parental mediation.


2. Staff of the Commission ("Staff") recommends settlement of the allegations against Paradigm and McCarthy (the "Respondents") in accordance with the terms and conditions set out below. The Respondents agree to the settlement on the basis of the facts set out in Part IV herein and consent to the making of an Order against them in the form attached as Schedules "A" and "B" on the basis of the facts set out in Part IV herein.
3. This settlement agreement, including the attached Schedules "A" and "B" (collectively, the "Settlement Agreement") will be released to the public only if and when the Settlement Agreement is approved by the Commission.
4. Staff and the Respondents agree with the facts set out in Part IV herein for the purposes of this Settlement Agreement only and further agree that this agreement of facts is without prejudice to the Respondents in any other proceeding of any kind including, but without limiting the generality of the foregoing, any proceedings brought by the Commission under the Act or any civil or other proceedings which may be brought by any other person or agency.
5. Paradigm is registered in Ontario as a broker and investment dealer. During the material time Paradigm was acting as a co-lead agent in connection with a private placement of special warrants to be issued by Bioscrypt Inc. ("Bioscrypt"), a reporting issuer in Ontario, listed and posted for trading on the Toronto Stock Exchange ("TSX"), under the trading symbol "BYT".
6. McCarthy is a shareholder and institutional salesperson at Paradigm and is registered in Ontario as a salesperson. McCarthy owns a 6.5% equity interest in Paradigm. During the material time McCarthy, on behalf of Paradigm, was actively involved in the sale of special warrants being issued by Bioscrypt by means of a private placement.
7. By letter dated October 11, 2001, Bioscrypt was advised by National Bank Financial Inc. ("NBF") that a syndicate of agents would be formed to work with Bioscrypt in connection with a proposed private placement of special warrants (the "Offering"). NBF agreed to invite Paradigm, as well as other securities dealers, to act as an agent. The letter specified that Paradigm was to be allocated 42.5% of the Offering and that the terms of the Offering were to include the following: that the special warrant would be exercisable for no additional consideration into a common share; that the Offering would be for gross proceeds of $10 million; that the agents would market the Offering on a best efforts basis; that the Offering would close on November 13, 2001; and that the agents' commission would be 6.5% of the gross proceeds of the Offering, as well as compensation options. On October 12, 2001 the President and CEO of Bioscrypt, Pierre Donaldson ("Donaldson"), accepted the terms and conditions set out in the October 11, 2001 letter, subject to a minor amendment specifying that only 5% commission would be paid in connection with gross proceeds received from insiders.
8. On October 11, 2001, Paradigm placed Bioscrypt on a Restricted List. It was the policy of Paradigm at that time to place an issuer on its Restricted List in circumstances where: Paradigm had been asked to act as an underwriter in a public offering; Paradigm was working on an engagement which was sufficiently developed; and, where Paradigm was in a special relationship with the issuer according to section 76(5)(b) of the Securities Act (Ontario) (the "Act"). Pursuant to the Paradigm policy, once a security was placed on the Restricted List, trading in that security was limited to: normal market making; unsolicited orders; and, transactions as part of a basket for hedging, provided that any trading was done by persons who did not have knowledge of any material non-public information. The security could be removed from the Restricted List where the material non-public information had been generally disclosed to the marketplace, for example, upon the issuance of a press release covering all of the relevant facts.
9. On October 17, 2001, a meeting was held at the offices of NBF attended by the members of the syndicate, including Paradigm, and management of Bioscrypt. At this meeting, a dry run was held of the presentation which was to be given during a cross country "road show" which was to commence on October 22, 2001. The dry run included the presentation of the Terms of the Issue (the "Terms") which specified the nature of the security being offered (special warrants), the size of the Offering (approximately $10 million, of which $1 million had been committed to by Donaldson), the closing date (November 13, 2001), the escrow conditions, and the agents on the Offering.
10. By letter dated October 17, 2001, Bioscrypt made an initial request to the TSX to grant price protection in respect of the Offering, noting that the closing price of Bioscrypt's common shares on October 16, 2001 was $2.38. In a further letter to the TSX dated October 22, 2001, Bioscrypt provided additional details in respect of the terms of the proposed Offering including the fact that insiders of Bioscrypt intended to participate in the Offering. By letter dated October 26, 2001 the TSX confirmed that price protection had been granted by the TSX to yield a minimum issue price of $2.12 per special warrant. A subsequent amendment of the price protection was sought by Bioscrypt on October 30, 2001 in order to reflect the closing price of Bioscrypt's common shares of $1.95 on October 29, 2001. The TSX granted the amendment, but only in respect of arm's length purchasers of the Offering. As a result, the special warrants were ultimately issued to arm's length purchasers at $1.60, and to insiders (i.e. Donaldson) at $1.74.
11. In the period October 22, 2001 to October 30, 2001 the road show was conducted. A series of presentations to market the Offering were made to various institutional investors in Montreal, Toronto, Winnipeg and Vancouver by senior officers of Bioscrypt, and representatives from the syndicate. At these meetings, the Terms of the Offering were discussed with the would-be investors. In addition to the formal "road show" presentations, during this same period, the members of the syndicate also solicited the interest of institutional investors via telephone communications.
12. On November 2, 2001 Bioscrypt issued a press release in respect of the Offering announcing that NBF, as lead agent, together with Paradigm as co-lead, and two other securities dealers, had agreed to act as agents on a "best efforts" basis in connection with a private placement of $10 million of Special Warrants to be issued at $1.60 each. The private placement closed on November 14, 2001.
13. On October 18, 2001, McCarthy sent an e-mail to Eden Rahim, a portfolio manager at RBC Global Investment Management Inc. ("RBC GIM"), forwarding a copy of the Terms of the Offering. McCarthy suggested that a meeting be held the following week, at which Bioscrypt's CEO, Donaldson, would attend. Rahim managed the Royal Canadian Growth Fund ("RCGF") which held, at that time, approximately 1,551,100 freely trading shares of Bioscrypt. Approximately 570,000 of these shares had been purchased in the period July 1 to September 30, 2001 in an RBC GIM account at Paradigm in respect of which McCarthy was the institutional salesperson.
14. On or about October 26, 2001, a meeting was held with Rahim at the offices of RBC GIM attended by McCarthy and Donaldson. During the course of the meeting a presentation was made to Rahim in respect of the Offering. By no later than October 30, 2001, Rahim advised McCarthy that he intended to invest $2 million in the Offering on behalf of the RCGF.
15. Contemporaneous with confirming Rahim's interest on behalf of the RCGF in the Offering, McCarthy also discussed with Rahim participating in what McCarthy described as an "overtrade" involving the freely trading shares of Bioscrypt held by the RCGF. An "overtrade" was understood to be an investment strategy that resulted in an investor purchasing freely trading shares in a company from an existing shareholder with the existing shareholder replacing those shares by purchasing shares on a new issue from the company's treasury.
16. On October 31, 2001, McCarthy e-mailed Rahim, stating "I need to talk to you on BYT, we are closing the books tonight and I want to make sure that we are clear on a few things. I have you in the book for $2m plus the overtrade, which we talked about being 450,000 shares at $1.70, but I could make that slightly bigger if you are interested. Please give me a call."
18. During the course of the road show in respect of the Offering, certain institutional investors, including Synergy Asset Management Inc. and Canadian Pacific Management Limited, advised Paradigm that they were not interested in purchasing securities pursuant to the Offering (which securities were subject to certain resale restrictions), but were interested in purchasing freely trading stock.
19. Peter Hodson ("Hodson") was a portfolio manager at Synergy Asset Management Inc. ("Synergy") serving as lead manager for the Synergy Canadian Small Cap Fund. Synergy was a client of Paradigm. On October 23, 2001, Hodson met with officials from Bioscrypt and Paradigm during which time a presentation was made in respect of the Offering. Hodson declined to purchase special warrants under the Offering but advised Paradigm that Synergy would be interested in purchasing freely trading shares of Bioscrypt. On November 1, 2001 Synergy placed an order to purchase up to 150,000 shares of Bioscyrpt at $1.70.
20. Chayanne Fickes ("Fickes") was a portfolio manager with Canadian Pacific Management Limited ("CP") where she managed the Canadian Pacific North American Pension Trust. CP was a client of Paradigm. On or about November 1, 2001, Fickes became aware of a block of Bioscrypt stock being made available. As a result, on November 1, 2001 CP placed on order to purchase up to 450,000 freely trading shares of Bioscrypt at $1.70.
21. On November 1, 2001, trading in shares of Bioscrypt opened at a price of $1.90. In order for Paradigm to complete the "overtrade", which was to be filled at $1.70, it was necessary for Paradigm to displace all better-priced bids in the market to achieve the "crossing" price for the overtrade. By means of 34 sell transactions, totaling 56,100 Bioscrypt shares (which formed part of the 600,000 shares to be sold on the "overtrade" by RBC GIM), the price of Bioscrypt was brought down to $1.70. The purchasers of these 56,100 shares, at an average price of $1.7984, had no knowledge of the Offering at the time their buy orders were filled by Paradigm on November 1, 2001.
22. Once the share price was brought down to $1.70, the cross of the remaining 600,000 shares from the "overtrade" was executed. The 56,100 shares sold to bring the price down were deducted on a pro-rata basis from the orders placed by Synergy and CP. As a result of the "overtrade", Synergy purchased 135,000 shares at $1.70; CP purchased 408,900 at $1.70; and RBC GIM sold 600,000 shares at an average price of $1.7092.
23. In connection with the sale of the 600,000 special warrants to the RCGF and the cross of the 600,000 shares further to the overtrade, Paradigm earned a commission of $43,340. In addition to these commissions, Paradigm also received 24,000 compensation options in connection with the sale of the 600,000 special warrants sold to the RCGF which options were exercised and subsequently sold at a profit to Paradigm of $12,415. Paradigm's total profit with respect to these transactions was $55,755.
• The Paradigm employees who were involved in arranging and executing the overtrade did not intend to breach any aspect of Ontario securities law, but simply failed to appreciate that the overtrade resulted in shares of Bioscrypt being sold by a person who had knowledge of the Offering to persons who had no such knowledge. Paradigm has cooperated fully with Staff's investigation of this matter since the outset. In addition, on its own initiative Paradigm has retained outside counsel to revise Paradigm's restricted list policy to ensure that all of its employees are fully aware of the potential ramifications of overtrades in connection with private placements.
25. McCarthy did not intend to breach any section of the Act or any policy of the Ontario Securities Commission. At the time he believed that the purchasers of the overtrade stock (i.e. Synergy and CP) were aware of the private placement. He did not turn his mind to the fact that the trades necessary to achieve the crossing price for the overtrade, i.e. the 56,100 shares, would or could be sold to persons without knowledge of the private placement which was scheduled to be announced the next day. McCarthy did not himself make those trades, although he was aware that they were being made. There was no commission charged or received with respect to the sale of the 56,100 shares. Although McCarthy is a 6.5% equity owner in Paradigm, he received no direct commission or fee credit with respect to the overtrade or any aspect thereof.
26. Paradigm's conduct was contrary to the public interest in failing to properly supervise and restrict the activities of McCarthy, and other employees, in connection with the conduct of secondary market trading in shares of Bioscrypt, at a time when Bioscrypt was on the Paradigm Restricted List as a consequence of Paradigm agreeing to act as an agent for the purpose of an offering which had not been generally disclosed to the public.
27. McCarthy acted contrary to the public interest by agreeing to facilitate a transaction in the secondary market, the "overtrade", which resulted in shares of Bioscrypt being sold by persons, with knowledge of a material fact which had not been generally disclosed, to persons who had no knowledge of that material fact, despite Bioscrypt having been placed on a Paradigm Restricted List.
30. If this Settlement Agreement is approved by the Commission, Staff will not initiate any proceeding under Ontario securities law in respect of any conduct or alleged conduct of the Respondents in relation to the facts set out in Part IV of this Settlement Agreement, subject to the provisions of paragraph 34 and 35 below.
31. Approval of this Settlement Agreement shall be sought at the public hearing of the Commission scheduled for June 11, 2004 or such other date as may be agreed to by Staff and the Respondents.
32. Staff and the Respondents may refer to any part, or all, of the Settlement Agreement at the Settlement Hearing. Staff and the Respondents also agree that if this Settlement Agreement is approved by the Commission, it will constitute the entirety of the evidence to be submitted respecting the Respondents in this matter, and Respondents agrees to waive their rights to a full hearing, judicial review or appeal of the matter under the Act.
33. Staff and the Respondents agree that if this Settlement Agreement is approved by the Commission, neither Staff nor the Respondents will make any public statement inconsistent with this Settlement Agreement.
34. If the Respondents fails to honour the agreement contained in paragraph 33 of this Settlement Agreement, Staff reserve the right to bring proceedings under Ontario securities law against the Respondents based on the facts set out in Part IV of this Settlement Agreement, as well as the breach of the Settlement Agreement.
35. If the Settlement Agreement is approved by the Commission, and at any subsequent time the Respondents fails to honour any of the Terms of Settlement set out in Part V herein, Staff reserve the right to bring proceedings under Ontario securities law against the Respondents based on the facts set out in Part IV of the Settlement Agreement, as well as the breach of the Settlement Agreement.
36. If, for any reason whatsoever, this Settlement Agreement is not approved by the Commission or an Order in the form attached as Schedules "A" and "B" is not made by the Commission, each of Staff and the Respondents will be entitled to all available proceedings, remedies and challenges, including proceeding to a hearing of the allegations in the Notice of Hearing and Statement of Allegations, unaffected by this Settlement Agreement or the settlement negotiations.
37. Whether or not this Settlement Agreement is approved by the Commission, the Respondents agree that they will not, in any proceeding, refer to or rely upon this Settlement Agreement or the negotiation or process of approval of this Settlement Agreement as the basis for any attack on the Commission's jurisdiction, alleged bias, appearance of bias, alleged unfairness or any other remedies or challenges that may otherwise be available.
38. The terms of this Settlement Agreement will be treated as confidential by all parties hereto until approved by the Commission, and forever if, for any reason whatsoever, this Settlement Agreement is not approved by the Commission, except with the written consent of both the Respondents and Staff or as may be required by law.
39. Any obligations of confidentiality shall terminate upon approval of this Settlement Agreement by the Commission.
40. This Settlement Agreement may be signed in one or more counterparts which together shall constitute a binding agreement.
41. A facsimile copy of any signature shall be effective as an original signature.
Dated this _ 7th ___day of _ June , 2004.
Dated this 9th day of June , 2004 "Michael Watson"
(e) that pursuant to s.127.1, Paradigm make a payment of $30,000 to the Ontario Securities Commission in respect of a portion of the costs of the investigation and this proceeding.


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Moncler Bruant Belted Utility Coat Details Moncler "Bruant" utility coat. Approx. 37"L down center back. Stand collar; two-way zip front. Long sleeves; logo patch at left. Adjustable self-tie waistline. Side slip pockets. Below hip length. Nylon shell and lining. Imported.


For those who are recovering from injury or who live with mental or physical disability, the human-horse relationship can open the door to an entirely new realm of possibilities. Horse and human become partners in a therapeutic relationship which offers a multitude of opportunities to focus on and explore abilities rather than disabilities. Students learn to be at ease, rather than dis-eased.
Physical aging, another component is known to be the cumulative effects of lifestyle choices, and unfortunately, many people with injury/disability necessarily lead sedentary lives. Furthermore, the ability to live independently depends largely on a person's degree of mobility, and sedentary lifestyle contributes to mobility issues. Therapeutic horseback riding improves the strength, tone, flexibility, and reflexes of postural muscles and leg muscles, thereby increasing stability of gait and balance in people with mild to moderate mobility disabilities. Those with more severe disabilities benefit from improved balance, coordination, and postural control essential to healthy respiratory and digestive function.
Carriage driving also addresses postural control, use of diaphragmatic and core muscle groups, eye and hand coordination and socialization and communication skills. Although clients aren't mounted, participation in this program increases physical activity levels even for clients in wheelchairs. These physical benefits contribute to the maintenance of independent lifestyles in individuals recovering from injury or living with disability.
Therapeutic horseback riding improves the strength, tone, flexibility, and reflexes of postural muscles and leg muscles, thereby increasing stability of gait and balance in people with mild to moderate mobility disabilities. Those with more severe disabilities benefit from improved balance, coordination, and postural control essential to healthy respiratory and digestive function. Carriage driving also addresses postural control, use of diaphragmatic and core muscle groups, eye and hand coordination and socialization and communication skills. Although students aren't mounted, participation in this program increases physical activity levels even for clients in wheelchairs. These physical benefits contribute to the maintenance of independent lifestyles in individuals recovering from injury or living with disability.
Individuals recovering from injury or living with disability need to be engaged in healthy, supportive relationships to help enhance their sense of self-confidence and autonomy, and to cope effectively with the challenges of their circumstances. Equestrian pursuits, by their very nature are an exercise in cooperation, connection and relationship building. They require the cultivation of mutual trust and respect, patience and compassion, assertiveness and sensitivity, focus and perseverance. Horses, like people, respond positively in relationships characterized by these elements. As students practice the use of these skills and qualities in the saddle and on the ground, horses respond in kind rewarding and reinforcing clients' development of healthy behaviors and coping mechanisms. These skills and qualities contribute to clients' ability to establish and maintain healthy relationships with family members and friends and helps develop an overall sense of self-confidence and autonomy; all of which enhance the individual's ability to cope with practically any challenge life offers.
Therapeutic horseback riding assists in building a good base for education by aiding in the students ability to learn. Therapeutic riding can help in the basic skill of remedial reading, by assisting students with the foundation of reading, recognizing the different shapes, sizes and colors. These educational lessons can be taught much more easily on horseback, as part of a games and activities. Remedial math is also learned by counting the horses steps, objects around the arena, or even the horses legs. Activities that involve addition and subtraction can be taught throughout a therapeutic riding session with the use of the horse, volunteers, and other students. With these concepts being taught through games willingness to learn and participate in increased.
Many adults recovering from injury or living with disability, particularly older adults, have limited opportunity for social interaction due to multiple factors including transportation, financial restrictions, and health issues. Decreased levels of social interaction and engagement have been shown to contribute to depression, self-neglect, a sense of loneliness and low self-esteem. Students are stimulated and find themselves interacting and engaging with volunteers, instructors, horse-handlers, therapists, other students, and the horses themselves. Moreover, volunteers and students vary in ages, from teens to senior citizens, providing enjoyable intergenerational interaction and the opportunity for students to make new friends and expand their social network.
Like recreational riding, therapeutic riding is an excellent form of exercise therapy that is fun, safe, challenging and socially rewarding. The goals of therapeutic and recreational riding revolve around learning horsemanship, improving basic riding skills and many times learning a specific riding discipline such as dressage or western pleasure. In therapeutic riding, special attention is paid to facilitating improvements in musical strength, coordination, balance, stamina, self confidence and social interaction. Lesson plans may be tailored individually to address clients' special needs. The therapeutic riding instructors are specially trained and certified to instruct students with a wide variety of physical and mental disabilities, as well as students who are not disabled. Therapeutic and recreational sessions are conducted according to each rider's interests, needs, abilities and rate of progress.


An implantable cardioverter defibrillator, also known as an ICD, is a medical device that is used to track heart rate to help prevent sudden death in high-risk patients with diagnosed ventricular arrhythmias.
An ICD is a battery-powered device that is implanted under the skin with wires running to the heart. If your heart falls out of sync and the device detects an abnormal heart rhythm, the device will send an electric shock to the heart in an effort to restore the normal heartbeat.
Who is candidate for an implantable cardioverter defibrillator?
Also for you to be considered for a ICD, your doctor must have ruled out other causes of your symptoms, including drug toxicity, electrolyte imbalance or inadequate blood flow to the heart muscle.
How is an implantable cardioverter defibrillator implanted?
An ICD, which is approximately the size of a small cookie, is implanted under the skin in the chest or abdomen. Leads will be run from the device to the heart through the blood vessels. X-rays will be used to place the leads correctly in the heart. Once the device is in place, your doctor will test it to ensure it is working correctly.
The ICD batteries last approximately seven years before having to be replaced.
Why get an implantable cardioverter defibrillator?
Implantable cardioverter defibrillators can reduce a person's risk of sudden cardiac death.
Complications from ICD implantation are rare. If you have a serious complication, such as bleeding around the heart, blood leaking through the heart valve where the ICD is place or a collapsed lung, you should seek medical attention immediately.
After your ICD has been implanted, you will stay in the hospital for one to two days. Your doctor and care team will test the ICD before you will be discharged to determine if it is working correctly.
If you experience pain after the implant, you can take pain medication such as Tylenol or Advil. If the pain is severe, your doctor may prescribe stronger medications. Do not take aspirin as it can cause severe bleeding.
Although most patients will be able to drive a week after the implant, some patients are advised not to drive for up to six months if you had a previous heart attack or ventricular arrhythmia. Your doctor may also recommend refraining from contact sports, lifting heavy objects (more than 5 pounds), vigorous activity or exercises for a month or more.
Also, if you are traveling via airplane, your ICD may set off security alarms. Your doctor can give you a card that identifies that you have an ICD.


A few days ago I got a wonderful letter (actually an email), asking about knitting.
The author wanted to see a particular garment from an earlier iteration of my website.
She also wondered why I have so little knitting on this one.
looking for the vest she remembered.
Alas, I found not a single pixel.
Not a single pixel of that sweater, that is.
 But I did find plenty of others.
some of which remain swatches.
Swatch Blanket -- approx 70" x 50"
wrapping around needles, loop through loop, through loop.
I've been knitting steadily and obsessively since my early teens.
Like breathing, it is something I can't seem to stop doing.
Why, then is there so little knitting on this website?
Why a tapestry archive and no knitting one to balance it?
Is the dreaded art/craft hierarchy warping my thinking?
is that my professional life used to be more knitting centric than it is now.
both for the magazine or book in question and for my records.
But as tapestry came to dominate the portion of my work that was "out in the world,"
my knitting became private, my sweaters my everyday clothes.
And who wants to see that?
so I stopped writing down the patterns -- or only as jots on fragments of paper.
while the original sweater lives in a pile with all the others).
But clothes are important. I like making them.
so I don't lose track.
Cloisters; published in Spin Off at some point (can't remember the date just now), but I put it here because it is what I am wearing today.
hardly fit for a knitting archive.
Miracle Medium #1 - Cormo Hoggett Fleece (brown overdyed with indigo). Top down.
They wouldn't have to be terrific photos, would they?
Knitting Pile several years ago. It is bigger now.
One of these fine days, I might actually do it.
Ah, Margaret - my comrade in clothing-- thank you. It is a wondrous thing to be able to have our work out in the world keeping ourselves and our dear ones cozy. This, for me, is what drives it all (well, that and the bliss of yarn in my hands of course). Also a delight to notice color leanings over time! I seem to be entering a yellow phase --or maybe it is that yellow is sneaking up on me, as my two yellow sweaters are not of hand spun, but rather yummy commercial yarn (Palouse Yarn Company and Mountain Meadows), that, for all my spinning and dyeing, I could not go home without. Now I think I need to dye a bit of that sunshine myself. And here I thought I was all about blue and brown and green.... You?
I am a green/rust person but in looking at all my garments I am a bit surprised at how much pink has snuck in their!! Mostly things I have made for family that they no longer wear and have returned. Usually due to a change in body size not rejection. Your photos have inspired me to catalogue all my handspun/handknits into years or people. Probably a combination. My favorites have been the fair-isle jumpers done for my eldest son the fiddler. Mostly designed using EZ's percentage system and Sheila Mcgregors book of designs. Such fun.
I could not find an email to send you this link my apologies if this was not a proper way to attach a link. I thought the different ways these women weave would interest you and perhaps you have already seen this. Love your work.
Your knitting is as beautiful and as varied as your tapestry. My mother taught me to knit when I was about seven years old . iItis me of my cherished memories, along with the memories of her teaching me crochet, sewing, and embroidery. I feel that these were gifts she gave to me and my sister because they have brought us joy and friendship our whole lives.
I so agree Debra, and am endlessly grateful to those who got me going-- both my grandmothers and my mother who, though she didn't care for needlework herself, recognized my passion for it and made sure I had supplies from an early age. The amazing part is how this business of manipulating yarn and thread, of making and embellishing fabric, just keeps unfolding and opening out in new and thrilling ways. Thank you for writing!
Just love all your making, but am really inspired by your tapestry weaving. To me it's the best type of weaving as it allows for a lot of creativity. For some time I had been wondering on how to finish a tapestry and none of the methods seem satisfying, but then I came across the four selvedge tapestry!! Thank you for that.
Would love to follow your blog, but somehow it won't allow me to?!?
Thank you for your kind words, Martina. I am so happy that the four selvedge instructions found you! A life changing technique for many of us.
One way to follow my blog is to sign up for the newsletters which have links to recent posts. I think the sign up thing should be working. If it doesn't, please let me know.
Of course I only write newsletters every few weeks, so I think it is also possible to add the URL of the site to an RSS reader if you have one. I don't know quite how this works, but apparently it lets you know every time I put up a new post. There is also the old fashioned calendar way -- I try to post on tuesdays (with the occasional wednesday), and so far have managed to be pretty consistent.


The Dow Jones Industrial Average gained 1.3%, the Nasdaq Composite gained 1.4%, and the Russell 2000 gained 1.3%. The S&P 500 energy (+3.2%), real estate (+2.9%), consumer staples (+2.9%), and industrial (+2.6%) sectors led this week's advance. On the other hand, the consumer discretionary (-0.1%), financials (+0.1%), and materials (+0.8%) sectors underperformed. What proved to be a rallying cry for the market this week was the Fed. In particular, the idea that the Fed has pivoted from being a foe to a friend with its monetary policy outlook sparked broad-based buying interest and allowed the S&P 500 to break above its 2700 level for the first time since Dec. 7.
Specifically, the Federal Open Market Committee and Fed Chair Powell on Wednesday indicated the Fed is content with being patient with its policy approach and is open to curtailing its balance sheet normalization effort if necessary. Also, the FOMC voted unanimously to keep the fed funds target rate range unchanged at 2.25% to 2.50%, as expected. This week also saw the U.S. and China resuming trade talks in Washington and a host of earnings reports that were generally mixed but were not as bad as anticipated. Regarding earnings, Dow components Apple (AAPL), Boeing (BA), 3M (MMM), Pfizer (PFE), Exxon Mobil (XOM), Chevron (CVX), and Merck (MRK) pleased investors with their results. On the other hand, Caterpillar (CAT), Microsoft (MSFT), Visa (V), DowDuPont (DWDP), McDonald's (MCD), and Verizon (VZ) underwhelmed. In addition, widely-held shares of Facebook (FB) and General Electric (GE) surged following their reports, while Amazon (AMZN) fell on disappointing guidance.
U.S. Treasuries saw increased buying interest following Wednesday's FOMC decision and Fed Chair Powell's press conference. Treasuries pulled back on Friday, though, after a stronger-than-expected Employment Situation Report for January, which showed that nonfarm payrolls increased by 304,000 (Briefing.com consensus 160,000). The 2-yr yield finished the week down 11 basis points to 2.50%, and the 10-yr yield fell nine basis points to 2.69%. The U.S. Dollar Index fell 0.2% to 95.66. WTI crude rose 3.0% to $55.28/bbl.


text:
Richard Childress Racing to announce plans for a third Cup team 'at a later date'
By Nate RyanJul 26, 2017, 11:10 AM EDT
Sarah Crabill/Getty Images
With Paul Menard and his family's home improvement chain sponsorship on the move to Wood Brothers Racing for 2018, Richard Childress Racing has a major funding gap to address.
Menards has adorned the No. 27 Chevrolet for RCR for seven consecutive Cup seasons and is among the last full-season sponsors in NASCAR's premier series. It assuredly is the most lucrative of RCR's sponsorships.
Though the team is committed to fielding Chevys for Ryan Newman and Austin Dillon next season, the impending departure of Menard leaves questions about whether RCR will remain a three-car team in 2018.
In a statement Wednesday morning, team chairman and CEO Richard Childress said the team "will be announcing our plans for a third Cup team and our overall 2018 team lineup at a later date."
Here's the full statement from Childress:
Paul Menard and Menards, Inc. have had a partnership with RCR for seven years. Together, we have enjoyed a tremendous amount of success, including Paul's emotional win at Indianapolis in 2011. He is a very talented driver and a good friend. Everyone at RCR wishes both Paul and Menards nothing but the best in the future.
Our entire RCR organization is 100 percent focused on getting all three of our Monster Energy NASCAR Cup Series programs in the playoffs this year, and bringing another Cup championship to RCR in 2017.
We will be announcing our plans for a third Cup team and our overall 2018 team lineup at a later date.


We use Zweigart linen and Aida fabric for our kit production and we also supply these fabrics by post. The reason for supplying Zweigart fabric is that it is simply the best!
All the linens on this web site (unless stated) are evenweaves - this means that if you counted the threads across and down the fabric, the thread count would be the same. This is why your cross stitches are square!
We supply our materials in fat quarters, long quarters, half metres or metres. A fat quarter is 50cm one way and half the width of the roll the other way. This means that when supplying linen, the fat quarter is almost always 50 x 70cm.


Has anyone tried the Orchard Bank Credit Card Application before?
i want to ask with a secure credit card from orchard bank?
i want to ask about orchard bank credit cards when filling out the application?
Orchard Bank Secured Credit Card?
Any secured card will build your credit, it does not matter who the issuer is, as long as it is reported to the credit bureau.
Orchard bank is a company known for helping people rebuild credit.
How long does it take to receive a secured credit card from orchard or household bank in the mail?
If Orchard said 12-14 days after the application is received, allow 3 weeks. If HSBC said 30-45 days, allow two months.
I have one orchard credit card and I have scored more than 400 points from it. There must be something wrong with your card. Contact with the bank and they will help you in sorting it out. Thanks for asking it here.
Thanks for helping to clear doubt on Orchard Bank Credit Card Application. This is a great site to clarify doubts on investments and share market terms. They have experts who give you the right answers and help you sort out the problems. Do post more such feeds.


text:
Baltimore insurance brokers file complaint accusing Erie Insurance of discriminating against Black customers
Right Stuff: O'Malley serving himself to the very end
By By Mike Collins and Correspondent
As Governor Martin O'Malley prepares to leave office, he is trying a few sneaky moves at the expense of Marylanders.
One of O'Malley's most egregious plans was buying a 255-acre farm with $2.8 million dollars of Program Open Space funds, and leasing it to a big campaign donor for $1 per year for 25 years. In addition, that donor's company would get a half-million grant to start an organic foods distribution hub.
Fortunately, Comptroller Peter Franchot shined light on the deal. The state still bought the farm, but the sweetheart lease may have embarrassed the donor, if not the governor or treasurer, and that part of the proposal was withdrawn.
But O'Malley has a few other tricks up his sleeve and is trying to administratively hamstring Governor-elect Larry Hogan before he can take office.
O'Malley has introduced more than 30 new rules since Election Day. Some, regulations include such mundane things as new fees on barbers and cosmetologists, which would take effect after O'Malley leaves office.
Others, however, are more significant. O'Malley has introduced major regulations on natural gas exploration and extraction that uses a technique known as hydraulic fracturing, or fracking.
Fracking in Western Maryland's coal region has the potential to bring hundreds of good-paying jobs to a region of the state that has not benefited from government's spending binge, the way the I-95 corridor has.
Tapping Maryland's portion of the Marcellus Shale also would make Maryland a major energy producer and exporter through the expanded Cove Point LNG terminal. And as coal-fired electric power plants are decommissioned, cheap natural gas has made production of electricity cleaner and more affordable, which is good for consumers and the environment.
O'Malley's regulations, however, would make energy companies comply with "the strictest rules for drilling in the country," thereby making it uneconomical to do so. This allows him to claim to have permitted energy exploration, while making it impractical to do.
O'Malley is also pushing new agricultural regulations. The proposed rules would reduce phosphate runoff from farms by limiting the use of manure and encouraging use of inorganic fertilizers. This will cost taxpayers an initial $15.5 million dollar subsidy. But it will raise cost on Eastern Shore farmers, hurt Maryland's agricultural industry, and drive up food prices for consumers.
Interestingly enough, the study the phosphate rules were based upon was released three days after the election, and regulations were ready one week later—a land-speed record for government action. They were completed in time to be submitted and become effective before Larry Hogan's inauguration.
As in his midnight deal for political donors, his tough regulations are about politics—and as always, it is about Martin O'Malley.
The sweetheart farm deal and raft of regulations were sprung after the election so as not to hurt the campaign of Anthony Brown and other democrats. There is also more than a little pique at play. The fracking and agriculture rules will stick it to those pesky counties that keep voting Republican and constrain Larry Hogan before he can take office.
O'Malley is also playing a long game. The recent elections strengthened the environmentalist wing of the Democratic Party at the expense of labor. This was best seen in the senate Democrats' filibuster of Senator Mary Landrieu's Keystone pipeline bill, effectively tossing her reelection bid under the bus.
O'Malley appears to have bet that his national political ambitions lay with left wing of presidential primary voters that dominate the Democratic Party and the billionaires who support them.
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There may be merit to O'Malley's proposed regulations. However, his sneaky approach is ungracious, undignified, and self-serving.
The new legislature and governor deserve to be able to have open and vigorous debate on fracking, agricultural runoff, and other issues, and develop solutions that fit the interests of all Marylanders, not just the one who is leaving Government House.
Brian Griffiths: Trump fans losing Twitter accounts aren't being denied free speech | COMMENTARY
Our Say: As redistricting looms, Anne Arundel can expect to get carved up again | COMMENTARY
Hal Burdett: There's poetic justice in the second impeachment | COMMENTARY
Reach Collins at MichaelCollins.Capital@gmail.com.
Larry Hogan
Mary L. Landrieu


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3 people shot in New Llano bar
Micah Pickering
A man from Fort Polk has been taken into custody after he allegedly shot three people at a bar in New Llano early Sunday morning.
The Vernon Parish Sheriff's Office received a call concerning shots fired at The Venue, a bar located in the area of Billy Goat Hill.
VPSO Deputies, New Llano Police Officers and Leesville Police Officers responded to the scene and took control.
During the course of the investigation, witnesses identified Andrez Shamad Jones as the shooter. Witnesses told authorities that the incident began with a disturbance that started in the bar.
The chaos would soon spill out of the bar, and witnesses said that Jones went to his vehicle and retrieved a firearm.
Witnesses stated that all attempts to restrain Jones failed because Jones began shooting in an erratic and reckless manner.
Jones allegedly fired at least six rounds into a crowd of people, injuring three. The crowd soon fled the area with several shoes and other being left behind.
One victim was shot in the calf, and the other two victims told authorities that they were both shots in the ankles. The victims were treated for their injuries at a local medical facility.
A 9mm handgun was found and taken into evidence.
Jones was arrested and charged with three counts of aggravated second-degree battery with a firearm and one count of illegal discharge of a firearm.
Bond has not been set and Jones remains in the VPSO jail.