text:
Regal Cinemas Parent Cinemark to Close All Theaters in US …
Regal Cinemas Parent Cinemark to Close All Theaters in US and UK
Regal Cinemas owner Cineworld is closing all of the chain's locations in the U.S., as well as its theaters in the U.K. in the wake of MGM and Universal's decision to delay the release of "No Time to Die" until next year, according to Variety.
The new closures, set to take effect as soon as next week, come just a few months after the company began reopening its locations amid the coronavirus pandemic earlier this summer. Cineworld operates 128 venues in the U.K. and Ireland in addition to Regal's 546 theaters in the U.S.
According to the Sunday Times, which first reported news of the Cineworld U.K. closures, the move puts up to 5,500 jobs at risk in that country alone.
*Also Read:* James Bond Film 'No Time to Die' Moves Release Date Again to 2021
The decision to close its locations comes a day after MGM and Universal announced that the latest James Bond film, "No Time to Die" would be pushed back again, with a statement from the filmmakers citing a need for the film "to be seen by a worldwide theatrical audience."
"No Time to Die" was initially set to hit theaters last April, but due to the coronavirus pandemic, it was moved to Nov. 20, then Nov. 25, and now to next April.
Following Disney's move to change release dates for many of its films — most notably "Black Widow," which was set for release on Nov. 6 but was moved to summer 2021 — the loss of "No Time to Die" leaves theaters with a dearth of major releases for the remaining months of 2020.
*Also Read:* AMC Theatres Credit Rating Downgraded Again by S&P Global, With Default Imminent
Last month, Cineworld reported a $1.6 billion loss in the first half of 2020, with group revenues sinking to $712.4 million from $2.15 billion in the first six months of 2019. The company said at the time it had been able to reopen 561 of its 778 locations worldwide.
"If governments were to strengthen restrictions on social gathering, which may therefore oblige us to close our estate again or further push back movie releases, it would have a negative impact on our financial performance and likely require the need to raise additional liquidity," the company said.
*Related stories from TheWrap:*
James Bond Film 'No Time to Die' Moves Release Date Again to 2021
'No Time to Die': Billie Eilish Music Video Teases New Footage From James Bond Film (Video)
'No Time To Die': Meet Rami Malek's 'Unsettling' Bond Villain in New Teaser (Video)
Entertainment Industry to Get $15 Billion in Aid as $900 Billion Stimulus Bill Passes
The Wrap 22 Dec 2020
Less than two weeks before year's end, Congress is set to finally pass a $900 billion stimulus package that will provide some..
AMC's Stock Surges 22% on New York Theaters Reopening
How '90s Disney Classics Like 'Hocus Pocus' Are Scaring Up Box Office Amid Pandemic Slump
New York Movie Theaters Outside of NYC Can Open at 25% Capacity, Cuomo Says
Chicken Soup for the Soul Entertainment's Screen Media to Bring 'The Outpost' Back to Theaters for Special Veterans Day Screenings
Midmorning With Aundrea - October 7, 2020 (Part 1)
WCBI 07 Oct 2020
(Part 1 of 4) With many colleges shut down or accepting only a limited number of students, many people are finding refreshing..
AMC Theatres Says It Will Be Out of Cash by Early 2021
As movies slip and Regal shuts doors again, many theaters may not survive the maelstrom
Pixar's 'Soul' bypasses theaters, will stream on Christmas
SeattlePI.com 08 Oct 2020
Regal Cinemas to temporarily close all U.S. theaters, including one in the Valley
bizjournals 07 Oct 2020

redpajama_set_name: RedPajamaCommonCrawl


text:
For Sale: Truman Capote's Ashes (Like, of His Body)
Filed to: things you could do with your moneyFiled to: things you could do with your money
things you could do with your money
joanne carson
why tho
julien's auctions
Photo via Getty Images.
If you've ever wanted to own the mortal remains of a famous 20th century author, here is perhaps your only shot: Truman Capote's ashes are going up for auction in September. You'll just have to beat the Addams Family to the punch.
That's according to Vanity Fair, which reports that in late September, Julien's Auctions will be holding a sale they're billing as a "peek inside the lives of some of Hollywood's most private stars," whose lots include Capote's ashes contained within "a carved Japanese wooden box," expected to sell for $4,000 to $6,000.
"I am sure people are going to think this is disrespectful," admitted CEO Darren Julien. Nevertheless!
"But this is a fact: Truman Capote loved the element of shock. He loved publicity. And I'm sure he's looking down laughing, and saying, 'That's something I would have done.' He was a larger-than-life character."
He also spoke a bit to the ethical issues involved.
"Yeah, but it's really body parts [that you have to worry about]," Julien said. "You can't sell things like that. But, I will say, Christie's sold Napoleon's penis years ago. And we sold William Shatner's kidney stone for $75,000. There's all kinds of precedents for this. Like I said, if it wasn't Truman Capote, we would pass because we wouldn't want to be disrespectful. And the antics he was always up to, and how much he loved press—it's no question that that is something he would have wanted done."
Apparently, Capote left part of his ashes to dear friend Joanne Carson, wife to Tonight Show host Johnny. (The rest supposedly went to his partner, Jack Dunphy.) The ashes have had an eventful afterlife.
According to Page Six, Carson kept the ashes in an urn in the room where he died. The remains were stolen twice, however—once during a 1988 Halloween party (before being mysteriously returned), and again at a party Carson hosted (with the urn in attendance) for a play about Capote. The culprit, however, did not make it out the door with the remains. In 2013, the ashes were even invited to the opening-night gala of Broadway's Breakfast at Tiffany's. ("We did try to get him here," a Breakfast rep confirmed at the time. "Joanne says he always wanted to (see) Holly Golightly open on Broadway, and we thought it would have been poignant for the entire company.") Alas, Carson did not want to risk another theft.
Carson died last year and, "basically, the estate didn't know what to do with them," said Julien. If this all gives you the willies, just consider it a testament to the importance of very clear and specific estate planning.
Biographer Unearths Unknown Harper Lee Article About the Clutter Murders
Liz Smith Shares Her Opinion on Basically Everyone Ever
Celebrities Insist They Actually Like Derek Blasberg


text:
Q: Regex select a (-) but ignore the selection if it is inside certain words (start-up|stop-off) I want to select and replace the dashes/hyphens ("-") with spaces (" ") in certain words (ex: "start-down" changes to "start down"), while ignoring the replace for other words (ex: "start-up" stays "start-up") using the PHP's preg_replace().
This is the regex that I have come up with:

(?<!(start))-(?!(up))|(?<!(start))-|-(?!(up))

Using the above regex on this data:

*

*start-up

*start-off

*anything-up

*stop-off

*start-off

*stop-up

Returns the following:

*

*start-up

*start down

*anything up

*stop off

*start off

*stop up

It works perfectly for start-up.  But I know down the road I'll need to add other exceptions to the list such as stop-off (ex: "stop-off" stays "stop-off").
So the question is this:
Should I do it via PHP's function, such as str_replace() and if else/switch case with an array of "unchangeable" words, loop through those and make appropriate changes if necessary or is there a way in regex to ignore some select if the select is part inside a certain word?

A: My php is a bit rusty, but here's what I'd suggest:
function do_replace($m) {
    return strlen($m[1]) > 0 ? $m[1] : ' ';
}

preg_replace_callback('/(start-up|stop-off)|-/', 'do_replace', $input);

If your version of PHP supports anonymous functions, you can do this:
preg_replace_callback(
    '/(start-up|stop-off)|-/',
    function($m) {
        return strlen($m[1]) > 0 ? $m[1] : ' ';
    },
    $input
);

The real benefit of this method is that it's very easy to extend to any number of 'special words' that you want to exclude.

A: You can use the pattern reset (\K) trick with preg_replace, example:
$input = 'passe-montagne, passe-partout, passe-murail, start-up, stop-off';

echo preg_replace('~\b(?>start-up|stop-off)\b\K|-~', ' ', $input);

All that is before \K is checked but excluded from the match result.
Notice: your pattern can be more efficient with this kind of tricks:
~\bst(?>art-up|op-off)\b\K|-~

redpajama_set_name: RedPajamaStackExchange


text:
# Creating a custom home page
>**Note: This part of customization example is currently not working. Will be fixed soon**

In this tutorial we'll update the application to use a customized home page.

> You can find the code of this tutorial [here](../../custom-webapp/gui/src)

## Prerequisites

1. You've completed the [getting started guide](../Getting-started.md)
2. You are familiar with [TypeScript](https://egghead.io/courses/up-and-running-with-typescript), [JavaScript (ES6)](https://egghead.io/courses/learn-es6-ecmascript-2015), [Webpack](https://webpack.js.org/) and [React](https://egghead.io/courses/react-fundamentals)

## Starting the application in debug mode

See [Starting the application in debug mode](./Change-the-skin.md#starting-the-application-in-debug-mode).

## Creating a new component which we will use as our home page

As a first step we'll create a new component called `Home`.

1. Create a new directory called `custom-components` inside the `gui/src` directory
2. Create a new file called `Home.tsx` in this directory
3. I've chosen to add a Welcome message and a link to the product family list page as content of my Home component

```typescript
import * as React from "react";
import { Link } from "react-router";
import { Utils } from "@sdl/delivery-ish-dd-webapp-gui";
import "./styles/Home";

const { path } = Utils;

const Home = (): JSX.Element => {
    return (
        <section className="custom-home-component">
            <h1>Welcome!</h1>
            <div>
                <Link to={`${path.getRootPath()}productfamilylist`}>Continue to the product family list</Link>
            </div>
        </section>
    );
};

export default Home;
```

4. We'll also add some styles to this by creating a less file called `Home.less` inside the `gui/src/custom-components/styles` directory

```less
@import (reference) "~theme-styles";

.custom-home-component {
    position: relative;
    top: 50px;
    padding-top: 1px;
    max-width: @screenXl;
    margin: 0 auto;

    h1 {
        display: inline-block;
    }
}
```

## Change the application routing to use our newly created page as the new home page

In the previous step we've created a new component. Let's enable this component for the `/home` url.
I'll also add routing for the `/productfamilylist` url where I'll use the `ProductFamiliesList` component.

To do this we'll need to add some children to the `App` component which is owning the routing of the application on the gui.

Update `gui/src/Main.tsx` as followed.

```typescript
import * as React from "react";
import * as ReactDOM from "react-dom";
import { Components, Services, IState, configureStore } from "@sdl/delivery-ish-dd-webapp-gui";
import { Provider } from "react-redux";
import { Store } from "redux";
import { Route } from "react-router";

// Custom imports
import "./custom-styles/skin-overwrites";
import Home from "./custom-components/Home";

const { App } = Components.AppComp;
const { PageService, PublicationService, TaxonomyService, SearchService } = Services.Client;
const { localization} = Services.Common;
const { ProductFamiliesList } = Components.ProductFamiliesListComp;

const mainElement = document.getElementById("main-view-target");

/**
 * Set instances for services
 */
const services = {
    pageService: new PageService(),
    publicationService: new PublicationService(),
    localizationService: localization,
    taxonomyService: new TaxonomyService(),
    searchService: new SearchService()
};

const store: Store<IState> = configureStore({});

localization.setStore(store);

const render = (AppComp: typeof App): void => {
    if (!mainElement) {
        console.error(`Unable to locate element to render application.`);
    } else {
        ReactDOM.render(
            <Provider store={store}>
                <AppComp services={services}>
                    <Route path="home" component={Home} />,
                    <Route path="productfamilylist" component={ProductFamiliesList} />
                </AppComp>
            </Provider>, mainElement);
    }
};
render(App);
```

To do this we've added two extra `Route` components inside the `AppComp`.
One to use our custom `Home` for the `/home` url and one to show the `ProductFamiliesList` for the `/productfamilylist` url.

We also imported `Route` from `react-router` and our custom `Home` component on the top of this example.

## Update GUI dev environment build script

In order to have the GUI build working for the new route we need to change `gui/build/gulp-tasks/serve.js`.

```javascript
// ...

const publicationContentRegex = /^\/[0-9]+.*$/gi; // All urls starting with a number
const publicationsListContentRegex = /^\/publications.*$/gi;  // Publication list
const productFamiliesContentRegex = /^\/productfamilylist$/gi; // Custom product families page
if (
  req.url.match(/^(\/home(;jsessionid=[\w\d]+)?)?$/gi) ||
  req.url.match(publicationContentRegex) ||
  req.url.match(publicationsListContentRegex) ||
  req.url.match(productFamiliesContentRegex)
) {
  req.url = "/index.html";
}

// ...
```

## Add a new controller to the Java backend

To have deep linking working we'll need to add a controller to match the new url.

1. Create a new controller class (`src/main/java/org/company/controllers/CustomController.java`)

```java
package org.company.controllers;

import com.sdl.webapp.common.api.model.page.PageModelImpl;
import org.springframework.stereotype.Controller;
import org.springframework.web.bind.annotation.RequestMapping;

import javax.servlet.http.HttpServletRequest;

import static com.sdl.webapp.common.controller.RequestAttributeNames.PAGE_MODEL;
import static org.springframework.web.bind.annotation.RequestMethod.GET;

@Controller
public class CustomController {

    /**
     * Custom routes for gui entry points
     *
     * @param request
     * @return
     */
    @RequestMapping(
            value = {"/productfamilylist"},
            method = GET
    )
    public String productFamilyList(HttpServletRequest request) {
        request.setAttribute(PAGE_MODEL, new PageModelImpl());
        return "home";
    }
}
```

2. Add a class to initilialize sprint configuration (`src/main/java/org/company/Initializer.java`)

```java
package org.company;

import org.springframework.context.annotation.ComponentScan;
import org.springframework.context.annotation.Configuration;

/**
 * Initializes Spring context for web application.
 */
@Configuration
@ComponentScan(basePackages = "org.company")
public class Initializer {
}
```

3. Update the web app initializer (`src/main/java/com/sdl/delivery/ish/webapp/WebAppInitializer.java`) to load the `Initializer` class

```java
package com.sdl.delivery.ish.webapp;

import com.sdl.delivery.ish.webapp.module.SpringInitializer;
import com.sdl.delivery.ish.webapp.module.controller.PageController;
import lombok.extern.slf4j.Slf4j;
import org.company.Initializer;
import org.springframework.web.WebApplicationInitializer;
import org.springframework.web.context.ContextLoaderListener;
import org.springframework.web.context.support.AnnotationConfigWebApplicationContext;
import org.springframework.web.servlet.DispatcherServlet;

import javax.servlet.ServletContext;
import javax.servlet.ServletException;

import static com.sdl.webapp.common.util.InitializationUtils.loadActiveSpringProfiles;
import static com.sdl.webapp.common.util.InitializationUtils.registerListener;
import static com.sdl.webapp.common.util.InitializationUtils.registerServlet;

/**
 * WebApp initializer.
 */
@Slf4j
public class WebAppInitializer implements WebApplicationInitializer {

    /**
     * Executed when the app starts.
     *
     * @param servletContext
     * @throws ServletException
     */
    @Override
    public void onStartup(ServletContext servletContext) throws ServletException {
        log.debug("Initializing servlet application context");
        AnnotationConfigWebApplicationContext servletAppContext = new AnnotationConfigWebApplicationContext();

        // Custom spring configuration is added to the end
        servletAppContext.register(SpringInitializer.class, PageController.class, Initializer.class);

        log.debug("Registering Spring ContextLoaderListener");
        registerListener(servletContext, new ContextLoaderListener(servletAppContext));

        log.debug("Registering Spring DispatcherServlet");
        registerServlet(servletContext, new DispatcherServlet(servletAppContext), "/").setLoadOnStartup(1);

        loadActiveSpringProfiles(servletContext, servletAppContext);
    }
}

```

redpajama_set_name: RedPajamaGithub


text:
FDA clears AI-based system to detect diabetic retinopathy
April 13, 2018, 7:19 a.m. EDT
The Food and Drug Administration has approved the first medical device to use artificial intelligence to detect more than a mild level of diabetic retinopathy in adults who have diabetes—a condition that leads to vision loss for about 24,000 Americans annually.
"Early detection of retinopathy is an important part of managing care for the millions of people with diabetes, yet many patients with diabetes are not adequately screened for diabetic retinopathy since about 50 percent of them do not see their eye doctor on a yearly basis," says Malvina Eydelman, MD, director of the Division of Ophthalmic, and Ear, Nose and Throat Devices at the FDA's Center for Devices and Radiological Health.
Eydelman adds that FDA clearance "permits the marketing of a novel artificial intelligence technology that can be used in a primary care doctor's office."
The IDx-DR device is a software program that uses an AI algorithm to analyze images of the eye taken with a specific retinal camera—called the Topcon NW400—and according to the regulatory agency is the "first device authorized for marketing that provides a screening decision without the need for a clinician to also interpret the image or results, which makes it usable by healthcare providers who may not normally be involved in eye care."
Also See: Most diabetic patients favor telehealth eye exams, survey finds
The device was reviewed under the FDA's De Novo premarket review pathway for some low- to moderate-risk devices that are novel and for which there is no prior legally marketed device. The agency evaluated data from a clinical study of retinal images obtained from 900 patients with diabetes at 10 primary care sites.
"In the study, IDx-DR was able to correctly identify the presence of more than mild diabetic retinopathy 87.4 percent of the time and was able to correctly identify those patients who did not have more than mild diabetic retinopathy 89.5 percent of the time," the FDA announcement states.
According to Michael Abramoff, MD, founder and president of IDx, the device is the first autonomous, AI-based diagnostic system authorized for commercialization by the FDA.
"The FDA's authorization to market IDx-DR is a historic moment that has the potential to launch a transformation in the way U.S. healthcare is delivered," says Abràmoff. "Autonomous AI systems have massive potential to improve healthcare productivity, lower healthcare costs, and improve accessibility and quality. As the first of its kind to be authorized for commercialization, IDx-DR provides a roadmap for the safe and responsible use of AI in medicine."
Abramoff adds that IDx is developing other AI-based diagnostic algorithms for detecting Alzheimer's disease, cardiovascular disease, glaucoma, macular degeneration and stroke risk.
RadiologyArtificial intelligenceDiagnosis and treatmentDiseases and conditionsFDA regulations


So i sat down with my laptop, notebooks and a big hot cup of Earl and got started.
I also remembered I hadn't taken a look in this month's Damernas (swedish fashion mag that I'm starting to like!) I like it and its become less old-lady like !


text:
1958 Cadillac Eldorado Brougham
Details of car above: One of 304 units built in 1958. The stainless steel top was the Brougham signature. These cars were built fully loaded with all options including memory seat.
Manufacturer Cadillac
Parent company General Motors
Production 1953–2002
Class Full-size personal luxury car
The Eldorado model was part of the Cadillac line from 1953 to 2002. The Cadillac Eldorado was the longest running American personal luxury car as it was the only one sold after the 1999 model year. Its main competitors included the Lincoln Mark Series and the lower-priced Buick Riviera.[citation needed]
Although cars bearing the name varied considerably in bodystyle and mechanical layout during this long period, the Eldorado models were always near the top of the Cadillac line. Nevertheless, and except for the Eldorado Brougham models of 1957–1960, the most expensive models were always the opulent, long wheel-based Series 75 sedans and limousines, not the Eldorado.
The name "Eldorado"
The name was proposed for a special show car built in 1952 to mark Cadillac's Golden Anniversary; it was the result of in-house competition won by Mary-Ann Marini (née Zukosky ), a secretary in the company's merchandising department. Another source, Palm Springs Life magazine, attributes the name to a resort destination in California's Coachella Valley that was a favorite of General Motors executives. However, the Eldorado Country Club in Indian Wells, California was not founded until 1957 – five years after Cadillac's naming competition. In any case, the name was adopted by the company for a new, limited-edition convertible that was added to the line in 1953.
The name Eldorado was derived from the Spanish words "el dorado", "the gilded one" or "the golden one"; the name was given originally to the legendary chief or "cacique" of a South American Indian tribe. Legend has it that his followers would sprinkle his body with gold dust on ceremonial occasions and he would wash it off again by diving into a lake. The name more frequently refers to a legendary city of fabulous riches, somewhere in South America, that inspired many European expeditions, including one to the Orinoco by England's Sir Walter Raleigh.
Assembly Detroit, Michigan, United States
4-door coupe
Layout FR layout
Engine(s) 365 ci 310 hp (230 kW) V8
331 ci 270 hp (200 kW) V8
Wheelbase 126 in (3,200 mm) (SWB)
129.5 in (3,290 mm) (1957-58 LWB)
129 in (3,300 mm) (1955-56)
Length 223.4 in (5,670 mm) (1958 LWB)
216.3 in (5,490 mm) (1957-58 SWB)
222.1 in (5,640 mm) (1957 LWB)
222.2 in (5,640 mm) (1956)
For 1955, the Eldorado's body gained its own rear end styling with high, slender, pointed tailfins. These contrasted with the rather thick, bulbous fins which were common at the time and were an example of Eldorado once again pointing the way forward.
For 1956, a two-door hardtop coupe version appeared, called the Eldorado Seville.
1957 saw the Eldorado (in both Biarritz convertible and Seville hardtop bodystyles) with a revised rear-end design featuring a low, downswept fenderline capped by a pointed, in-board fin. The rear fenders were commonly referred to as "chipmunk cheeks". This concept was used for two years, but did not spawn any imitators.1957 was chiefly notable for the introduction of one of GM's most memorable designs, the Eldorado Brougham. This four-door hardtop with rear-hinged rear doors was an ultra-luxury car that cost an astonishing $13,074 — more than the Rolls-Royce Silver Cloud of the same year. It featured a stainless steel roof, air suspension, the first memory power seats, and every other comfort and convenience feature available at GM at the time.


Taking your classic Bug or Bus on holiday abroad this summer? Don't spoil the classic lines of your VW with a magnetic GB badge or sticker.
This Cast Aluminium Detailed Black & Polished GB Badge is the perfect choice for installation on your Classic VW to keep yourself legal without spoiling the look of your car.
Supplied with a Stainless Steel bracket to allow an option for fitting; this can be adapted to suit most vehicles with some thought and an adapter bracket from your bumper mounts or similar.


text:
HomeRaymond AlmazanNorman Black thinks Raymond Almazan suffered major knee injury: 'He couldn't move his leg'
Norman Black thinks Raymond Almazan suffered major knee injury: 'He couldn't move his leg'
Raymond Almazan had an MRI at the Makati Medical Center following his knee injury. Ivan Saldajeno
QUEZON CITY--Prior to the PBA Governors' Cup Finals, many thought Meralco finally got the inside presence it needs to battle Ginebra's big men in Raymond Almazan.
But the best-of-seven series took a dramatic and potentially crucial turn early into Game 3 when Almazan hurt his left knee while trying to stop Japeth Aguilar.
[Related Story: Huge blow for Meralco as Raymond Almazan suffers knee injury]
Almazan never returned to the game, and worse, Coach Norman Black said afterward that the six-foot-seven center could be done for the series.
"We found out at halftime that we probably would lose Raymond possibly for the rest of the series," Black said.
Although the Bolts still managed to keep the game tight for the rest of the first half, Almazan's absence was felt in the third quarter, when the Barangay dropped 35 points to open a 20-point lead.
"From my viewpoint, they came out of the locker room really flat," Black told what he observed with his players during the halftime break. "The guys were a little bit down and lacked the energy and intensity going into the third quarter."
It turned to be enough for Ginebra to hang on as Meralco's fourth quarter rally came up short, and the latter conceded the 84-92 defeat at the Smart Araneta Coliseum.
[Related Story: Ginebra storms past Meralco to retake Governors' Cup Finals lead]
Almazan quickly left the arena, and according to Black, he went to the Makati Medical Center despite the current weather condition due to the Taal Volcano eruption to have an MRI for the extent of the knee injury. But based on what Almazan told Black at halftime, it looks like it may be a bad one.
"When I talked to him at halftime of the game, he couldn't move his leg, and being a former player myself, that's never a good sign," Black bared. "Having a swollen knee in the middle of a championship series is not something you can just bounce back from easily."
basketball Meralco Bolts Norman Black PBA Raymond Almazan


text:
Inebriated Shakespeare down for the count, with just 3 shows left
Actors attempt to "soliloquy under the influence" with Inebriated Shakespeare. There are only 3 performances left this season.
Inebriated Shakespeare down for the count, with just 3 shows left Actors attempt to "soliloquy under the influence" with Inebriated Shakespeare. There are only 3 performances left this season. Check out this story on Tennessean.com: https://www.tennessean.com/story/life/arts/2018/05/23/inebriated-shakespeare-down-count-just-3-shows-left/629271002/
Melinda Baker and Amy Stumpfl, Special to Nashville Tennessean / USA TODAY NETWORK – TENNESSEE Published 11:00 a.m. CT May 23, 2018
Mackenzie Smith as Oberon and Asa Ambrister as Titania in "A Midsummer Night's Dream."(Photo: Courtesy of PLC Photography)
Del Shores' brings 'Six Characters in Search of a Play' to Darkhorse on Friday-Saturday.
David Lusk Gallery opens 'Vestige' on Wednesday.
'Alan Cumming Sings Sappy Songs' at TPAC on May 31.
Final 'Happening in Nick Cave: Feat.' at Frist Art Museum on June 1.
Inebriated Shakespeare season winds down
If you like your theater with a little twist, Wildcard Productions' Inebriated Shakespeare has just the ticket. But time is running out, with just three performances remaining for the season — "A Midsummer Night's Dream" on Friday at New Heights Brewing Company and June 9 at Mercy Lounge, and "Much Ado About Nothing" on June 2 at Twin Kegs II.
The set-up is simple — a crew of daring actors begins the evening by drinking shots and then attempting to "soliloquy under the influence." Audience members can purchase shots for the actors (a $5 donation, which helps support the nonprofit theater company) — and maybe a few for themselves. (It's important to note that Inebriated Shakespeare encourages responsible drinking and designated drivers for both cast and audience.)
Tickets are $10, available at https://inebriatedshakes.com. Visit the website for complete details and schedule. Intended for mature audiences.
Poster image from Del Shores. (Photo: Submitted Art)
Del Shores' 'Six Characters in Search of a Play' at the Darkhorse
KB Productions will present Del Shores' "Six Characters in Search of a Play," this weekend only at the Darkhorse Theater.
Directed by Emerson Collins, this hilarious one-man show, which offers a twist on the classic Pirandello title, introduces us to six colorful characters that Shores has met in real life, but haven't quite found their way into one of his shows. These include: "Yvonne," the anti-vegetarian Dallas waitress; "Jimmy Ray," the evolving, Magic Mike-loving latent Georgia redneck; "Loraine," the once-brilliant drama teacher who has lost her mind and is now obsessed with porn; "Marsha," the monkey-hating lesbian with COPD; and "Aunt Bobby Sue," the racist Republican with a heart of gold.
Performances are at 7 p.m. Friday and Saturday at the Darkhorse Theater, 4610 Charlotte Ave., in Nashville. Tickets are $25, available at https://kbpresentsdelshores.brownpapertickets.com.
Kathleen Robbins, "Gravesite at Ryles Chapel," 2009, archival pigment prints, 30x30". (Photo: Image courtesy of David Lusk Gallery)
'Vestige' at David Lusk Gallery
On Wednesday, David Lusk Gallery opens a photography exhibition guest-curated by Sam Easley, president and founder of Crown Merchandise, and Jason Owen, president of Sandbox Entertainment. The influential music industry duo are also exemplary art collectors and "Vestige" showcases selections from their extensive photography collection that explore the ghostly remnants of human impact.
The exhibition includes work by Caroline Allison, Kevin Cooley, John Duckworth, William Eggleston, Catherine Erb, Huger Foote, Kristi Hargrove, Shannon Randol, Kathleen Robbins, Jack Spencer, Jeane Umbreit and William Wegman.
The exhibition is up through June 30 and an opening reception will take place 5-8 p.m. June 2, during the First Saturday Arts & Music crawl at Wedgewood-Houston. The gallery is at 516 Hagan St. Its hours are 10 a.m.-5:30 p.m. Tuesday-Friday and 11 a.m.-4 p.m. Saturday. Admission is free.
Alan Cumming at Carnegie Hall,. (Photo: TrŽ)
'Alan Cumming Sings Sappy Songs' at TPAC
Alan Cumming has dazzled audiences worldwide, earning a Tony Award, an Olivier and an Emmy. Now, this multitalented actor, singer, writer, producer, director and humanitarian brings his highly-acclaimed cabaret show, "Alan Cumming Sings Sappy Songs," to the Tennessee Performing Arts Center.
Most recently seen on Broadway in the 2014 Roundabout Theater Company revival of "Cabaret," Cumming premiered "Sappy Songs" in 2015 at New York's legendary Cafe Carlyle. He has since toured the show throughout the U.S., Canada, Australia and the U.K. In February 2016, he returned to New York for a sold out, solo debut at Carnegie Hall, releasing a live album of the same name.
The performance is at 7:30 p.m. May 31 at TPAC's James K. Polk Theater, 505 Deaderick St., in Nashville. Tickets start at $50, available at tpac.org or by calling 615-782-4040.
Installation from Nick Cave "Feat." at Frist Art Museum. (Photo: John Schweikert)
Final 'Happening in Nick Cave: Feat.' at Frist
"Nick Cave: Feat." has been up at Frist Art Museum since November, and if you haven't seen it yet or want to re-experience it in new ways, the Frist will host the last of three installments of "Happening in Nick Cave: Feat." at 7 p.m. Friday June 1. Each event has allowed viewers to engage with Cave's work in unique ways, and for this "happening," local performers stationed throughout the galleries will respond to the works and engage with viewers to create an inspiring and memorable experience.
Nick Cave is best known for his exuberant "soundsuits," human-shaped wearable sculptures made from found materials that when worn create a fantastic, multi-sensory experience that powerfully express social issues. "Feat" presents a diverse survey of Cave's acclaimed work and will close on June 24.
The Frist Art Museum is at 919 Broadway. Its hours are 10 a.m.- 5:30 p.m. Monday-Wednesday; 10 a.m.- 9 p.m. Thursday and Friday; 10 a.m.- 5:30 p.m. Saturday; 1 p.m.-5:30 p.m. Sunday. Admission is $12; $9 for seniors and college students; $7 for active military; free for members and kids 18 and younger.
A stoneware Chibi Oni sculpture by Jo Mechan, Old School Farm Pottery's studio assistant. (Photo: Image courtesy of Converge)
'Potential of Clay' at Converge Nashville
Be sure to add Converge Nashville, the local curatorial collective in Wedgewood-Houston, to your regularly scheduled art program if you haven't already. Founded by husband and wife team Eric Malo, architectural designer, and Alysha Irisari Malo, artist, poet and curator, the organization is dedicated to presenting interdisciplinary, project-based art and design, lifestyle and cultural programming that has a positive social impact.
Its latest exhibition, "Potential of Clay," presents an array of pottery work from Old School Farm Pottery, a local nonprofit that produces unique dinnerware and provides impactful employment for adults with development and intellectual disabilities. In addition to showcasing the clay work of employees, the exhibition includes personal work by founder Julia Whitney Brown, pottery teacher and coordinator Rebecca Blevins and via OSFP's Artist Incubator Program, studio assistant Jo Mechan.
A reception will take place 6-9 p.m. June 2, during the First Saturday Arts & Music crawl at Wedgewood-Houston, and will feature Julia Whitney Brown doing live demonstrations of wheel throwing.
The show is up through July 6 and will be on display concurrently at Converge, located at 1224 Martin St. on the second floor of the SNAP building, and at Extension 1, their new satellite space located one block away at 1260 Martin St. Normal hours of each space are by appointment and admission is free.
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Read or Share this story: https://www.tennessean.com/story/life/arts/2018/05/23/inebriated-shakespeare-down-count-just-3-shows-left/629271002/
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You are at:Home»News»Industry News»The Scottish Are Britain's Biggest Cruise Spenders
The Scottish Are Britain's Biggest Cruise Spenders
By Claire Wilde on	 Industry News, News
Royal Caribbean has revealed that Scottish cruise passengers are more likely to splash the cash on a cruise holiday than any other British guests. Research demonstrates the Scottish are more prone to spend money on cabin upgrades and are significantly more likely to book another cruise within two years.
Royal Caribbean's UK managing director, Stuart Leven, revealed the statistics during the Scottish Passenger Agents Association (SPAA) annual dinner in Glasgow before announcing the cruise line was pumping additional funding into luring even more Scots onto the seas by widening the appeal of cruise holidays.
With new ships, sailing out of the UK, due to enter into service this year and a wide range of new fun features and activities to enjoy, cruise holidays are appealing to a wider demographic than ever before. A total of £3bn worth of new ships are set to launch in the next four years.
SPAA council member and cruise expert, Kennedy Cree, is enthusiastic about the growing cruise industry in Scotland.
"It is the big thing in travel at the moment, but there is overcapacity. Passengers have never had it so good, with so many different places to go. Every major operator is building new ships, and trying to find something different to offer, with Royal Caribbean the trend-setters.
"They provide a 'resort feel' to their ships – providing as much aboard as you would find on land."
P&O Cruises' Britannia is due to enter service in less than two weeks (14 March 2015) – set to be the largest ship permanently located in the UK. Royal Caribbean's Anthem of the Seas is due to take to seas for the first time next month, and will spend its first season sailing out of Southampton before relocating to New Jersey to complete Bahamas and Caribbean itineraries throughout the winter.
Images sourced via Royal Caribbean Press Center and Flickr Creative Commons. Credits: Dave Conner
Royal Caribbean has revealed that Scottish cruise passengers are more likely to splash the cash on a cruise holiday than any other British guests.
Claire Wilde
Claire has worked in the travel industry since leaving college in 1994. One of this blog's most regular contributors, Claire covers cruise news and industry trends.


sanding it, and sealing it was surprisingly easy and resulted in a unique set of natural tree limb coasters for morning coffee or a long tall glass of iced tea. You only need a few tools to make your own old tree limb set of coasters.
6. Wrap up your new set of nature's coasters with a pretty ribbon and give to your dear Mom to show her you still like to make her handmade gifts for Mother's Day.
Optional: Throw in a set of coffee mugs or iced tea glasses.
In my family, we have a motto: You can never own too many clamps.
For miter sawing a limb, I use one or two very small wedges to get the limb set, then clamp the limb in place. I put my left hand on the limb pretty far from the blade so I can keep a keep for what's happening, then saw with my hands and body fairly clear of anything that might go wrong.
any thoughts on the view that the coasters should not be sealed? the theory is that sealed, non-absorbant coasters allow condensation from a cold drink to run onto the surface the coaster is supposed to protect.
what siez miter saw do you use for the 4" or so coasters?
Question(s): Can I use fresh/green wood? Does it need to be dried (and if so, then how?). Also, is the stain necessary step? Thanks!
Please explain how to get branches to be consistently the same thickness. I end up with slanted, not flat, various sized discs that are uneven. How do you begin the first cut so all following are uniform in thickness? Is there a trick to this I just haven't figured out?
I love this project! It's so unique and beautiful. Thank you very much for sharing the tutorial. I just featured a link to this on my blog which you can check out here. I don't have a miter saw, so I'm going to have to wait until I visit my parents so I can use my dad's saw, but I can't wait until I can make this!
Looks like it was just some glue I had on hand for glass and metal but you could use that really sticky fabric glue too.
What kind of glue did you use to put the felt on the bottom?
This is super cool but I have to add a word of caution. I have made several items out of tree limbs and after lots of successful cutting on my chop saw I had one limb twist unexpectedly and, fortunately, just give me a major bruise and a broken saw, not a missing digit. Since then I have always cut uneven wood pieces (like limbs) by hand using a japanese hand saw. It takes forever but is totally worth it and much safer.
Fantastic!!! What a great finishing touch to rustic decor!
I totally love the simplicity, and the gorgeous results!


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package io.lumify.core.config;

import java.io.File;
import java.util.Map;

public class HashMapConfigurationLoader extends ConfigurationLoader {
    public HashMapConfigurationLoader(Map initParameters) {
        super(initParameters);
    }

    @Override
    public Configuration createConfiguration() {
        return new Configuration(this, getInitParameters());
    }

    @Override
    public File resolveFileName(String fileName) {
        return new FileConfigurationLoader(getInitParameters()).resolveFileName(fileName);
    }
}


text:
En matemàtiques, les primitives de certes funcions elementals no es poden expressar com a funcions elementals. Un exemple clàssic de funció d'aquest tipus és , la primitiva de la qual és (tret d'una constant) la funció error, que es troba habitualment en estadística. Altres exemples són  i .

Cal dir que la noció de funció elemental és merament una qüestió de convencions. Es pot decidir d'afegir la funció error a la llista de funcions elementals i, amb aquesta nova llista, la primitiva de  és elemental. Ara bé, no importa quant s'estengui la llista de funcions elementals, sempre hi haurà funcions a la llista tals que llurs primitives no hi seran.

La maquinària de la teoria diferencial de Galois permet determinar quan la primitiva d'una funció elemental es pot expressar ó no com una funció elemental. La teoria diferencial de Galois és una teoria que es basa en el model de la teoria de Galois. Mentre que la teoria algebraica de Galois estudia les extensions d'un cos algebraic, la teoria diferencial de Galois estudia les extensions dels cossos diferencials, és a dir cossos amb un operador derivació, D. La major part de la teoria diferencial de Galois és paral·lela a la teoria algebraica de Galois. Una diferència fonamental entre ambdues construccions és que els grups de Galois diferencials solen ser grups de matrius grups de Lie, mentre que en la teoria algebraica els grups de Galois solen ser finits.

Definicions
Per a qualsevol cos diferencial F, hi ha un subcos

Con(F) = {f de F | Df = 0},

anomenat les constants de F. Donats dos cossos diferencials F i G, G es diu una extensió logarítmica de F si G és una extensió transcendent simple de F tal que

Dt = Ds/s per algun s de F.

Això té la forma d'una derivada logarítmica. Intuïtivament, es pot veuret com el logaritme d'algun element s de F, en aquest cas, la condició és anàloga a la regla de la cadena ordinària. Però cal recordar que F no està necessàriament equipat amb un únic logaritme; es podrien afegir moltes extensions "pseudo-logarítmiques" a F. De forma semblant, una extensió exponencial és una extensió transcendent simple que satisfà

Dt = tDs.

Amb la prevenció anterior al cap, aquest element es pot veure com un exponencial d'un element s de F. Finalment, es diu que G és una 'extensió diferencial elemental de F si hi ha una cadena finita de subcossos des de F fins a G on cada extensió de la cadena és o bé algebraica, o bé logarítmica, o bé exponencial.

Exemple
Com a exemple, el cos C(x) de les funcions racionals d'una sola variable, té un operador derivada donat per la derivada habitual respecte d'aquesta variable. Les constants d'aquest cos són precisament els nombres complexos C.

Teorema basic
Se suposa que F i G són cossos diferencials, amb Con(F) = Con(G), i que G és una extensió diferencial elemental de F. Sian a de F, y de G, i se suposa que Dy = a (en paraules, se suposa que G conté una primitiva de a). Llavors existeix c1, ..., cn de Con(F), u1, ..., un, v de F tal que

En altres paraules, les úniques funcions que tenen "primitives elementals" (és a dir primitives que pertanyen, en el pitjor dels casos, a una extensió diferencial elemental de F) són aquelles que es poden escriure d'aquesta forma que prescriu el teorema. Així, a nivell intuïtiu, el teorema estableix que les úniques primitives elementals són les "funcions simples" més un nombre finit de logaritmes de funcions "simples".

Enllaços externs
 Differential Galois Theory, M. van der Put and M. F. Singer

Vegeu també
 Algorisme de Risch

Equacions diferencials
Integració simbòlica
Teoria de cossos

redpajama_set_name: RedPajamaWikipedia


text:
theOneliner.com: Handling the Truth
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Terrible vampire action, terrible teen romance. Now with added terrible.
Released in 2008, certified UK-12A. Reviewed on 24 Jan 2009 by Scott Morris
There's nothing new, I suppose, in the allure of vampires to girls of a certain tweenage, if the outbreak of ladypart dribbling over the deeply unremarkable Interview with a Vampire in girls of a certain tweenage during my formative years was anything to go by. Apparently, and as I am no longer down with the hoodie clad ASBO laden youth of today I must take this on faith alone, the current wet dream inducing franchise is the series of Twilight novels from Stephenie Meyer, these addressing the market directly rather than simply being incidentally attractive to it. This makes it obvious fertile ground for adaptation demographics, if not hope for a decent film.
As such it's not much of a surprise to find out that this a is a rubbish film that's made money hand over fist, but I guess I'm getting rather ahead if myself. Twilight sees the relatively quiet and reserved Bella (Kristen Stewart) move from her mother's baking hot Arizonan gaff to the cold, overcast, practically Scottish town of Fork, although to be frank 'town' is something of an overstatement, to be with her even more quiet and reserved father. The new school provides new friends, although the only one of any interest to us at the moment, although to be frank 'interest' is something of an overstatement, is Edward (Robert Pattinson).
Edward, and his extended family whom are simply not interesting enough to mention, are vampires. Sorry if I ruined the surprise. You can tell this, if not from their superhuman strength and speed also from their complexion, which isn't so much 'pale and interesting' as it is 'baker in a Norman Wisdom sketch that clumsily ends up covered in flour'. They are all, however, good vampires, inasmuch as they're paid up members to the local chapter of Blood Drinkers Anonymous. So that's fine then.
Bella is for some reason interested in the desperately unhealthy-looking Edward, although I suppose saving her life from an impending crushing by car would pique one's interest, but initially it seems that he wants nothing to do with her. Boo hoo. It soon transpires that although Edward is indeed interested, her unique scent also makes him want to take her out for a meal in the more traditional vampiric sense just as much as in he romantic way.
Cue an agonisingly long time of the pair making goo goo eyes at each other and spewing sappy dialogue that would make Attack of the Clones blush, before eventually another bunch of less socially integrated vamps show up and decide more or less at random to eat Bella, prompting a spot of chasing and violence that sadly looks as if it will spill over into the inevitable sequel. Oh, and all of this takes place next to a reservation of Native American werewolves. In case any of that seemed too sensible for you.
Now, if there's at least one slender hope for films what done have vampires in them, it's that they will, at some point, ruin someone's shit in an interestingly bloody fashion. Despite their many, many flaws, even the execrable Underworld series had the common decency to provide that. Thanks to our featured hero vampire family being, for want of an equally descriptive polite term, pussies, Twilight doesn't even deliver that. Hell, you could probably replace the concept of vampirism with being Amish and wind up with an identical tedious relationship drama. Admittedly with a somewhat less dynamic tacked on action ending, but seeing as that was just as disappointing as the rest of the film anyway I suppose it really wouldn't have made much odds.
It explores, I guess, the well worn theme of star crossed lovers, paths intertwined by fate and all that, in a sort of Shakespeare dropped on his head many times as an infant kind of way. It is, and let's be quite clear about this, dreadful on every level I can think of. Its action sequences, if indeed it's deserving of the plurality, are banal, it's central love story is so deeply dull and derivative that it quite literally makes Baby Jesus cry, and the acting from, well, everyone, is barely worthy of the term.
I suppose, if I'm being rational about it, that I have seen many films far worse than this one. However, it's still bland drivel of the lowest order and feeding this to teenagers is not an act to be encouraged, unless you want to acclimatise them to the disappointment so often found in multiplexes these days. Certification be damned, anyone of any age even contemplating seeing Twilight would be far better advised to seek out The Lost Boys or 30 Days Of Night. You have access to the Internet, don't you?
Were I in the business of passing quantifiable judgements, I'd award this 1/5 TippyMarks.
Kristen Stewart (Bella Swan)
Robert Pattinson (Edward Cullen)
Billy Burke (Charlie Swan)
Ashley Greene (Alice Cullen)
Kellan Lutz (Emmett Cullen)
Peter Facinelli (Dr. Carlisle Cullen)
All original content © 2002-2018 theOneliner.com. All images © their respective studios.


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RDM Technology BV
Weapons & Weapon Systems
Towed howitzer
Building on its experience in the production of modernisation packages for the 155 mm M114 towed howitzer, fully covered in a separate entry, RDM Technology has developed an upgrade package forthe widely deployed US 105 mm M101 series of towed howitzer originally developed over 60 years ago.
When upgraded, the M101 can fire more modern ammunition with enhanced range and lethality. The modernisation is accomplished by using a maximum of existing gun parts and only adopting new components where required.
In late 1990, an upgraded M101/33 howitzer was demonstrated to the Canadian Armed Forces in Canada.
By late 1993, three prototypes of the upgraded RDM Technology 105 mm M101/33 howitzer had been completed. The third weapon underwent extensive trials in Indonesia, which were completed late in 1993.
In 1992, RDM Technology and Royal Ordnance of the UK reached an agreement whereby the two companies will co-operate in marketing their 105 mm artillery systems.
In March 1994, RDM Technology was awarded a contract by Canada to upgrade 96 M101 (plus an option on another batch of 36 which has yet to be exercised) into the M101/33 calibre configuration for the Canadian Armed Forces with the complete programme to be carried out in Netherlands.
First weapons were shipped back to Canada late in 1995 and all work has now been completed.
All of the barrels for these conversions were supplied by Royal Ordnance Nottingham.
Chile has more recently awarded Royal Ordnance a contract to upgrade a substantial number of M101 s and details of this contract are given later in this entry under the RDM Technology/Royal Ordnance teaming arrangement.
The major modification includes the installation of a new Royal Ordnance 105 mm 33 calibre barrel with progressive rifling and a new muzzle brake. The M101 is also modified in a number of other areas including the incorporation of larger capacity equilibrators, new metering and recoil rod in the recoil system and new seals, replacement of the original elevating arc and reinforcement on the drawbar.
The new 105 mm 33 calibre barrel is ballistically similar to the latest generation of 105 mm artillery ammunition and is suitable for high pressures, with the design being for 4,500 bars.
It has progressive rifling (1.35 to 1.18) over a length of 2,794 mm whereas rifling is constant (1.18) over the last 306 mm (muzzle end). The barrel has 36 lands and grooves and provides a shot travel of 3,100 mm with a chamber volume of 2,507 cm2. This is identical to the standard M101, allowing the upgraded weapon to fire all existing types of 105 mm ammunition.
The modified breech mechanism is still of the horizontal sliding type, but due to the higher forces generated on firing, the original breech ring is replaced by a stronger one which allows it to use all modern ammunition types.
The remaining parts of the original breech mechanism can still be used including the firing mechanism. In order to reduce the increased load on trunnions and recoil when using new ammunition, a three-slotted muzzle brake is fitted to the threaded end of the barrel. This muzzle brake provides for a substantial reduction in the recoil forces while still maintaining blast overpressure within acceptable limits.
A modification to the recoil system was required due to the increase of the recoil momentum, resulting from the use of the 33 calibre barrel and more modern ammunition. The increased recoil momentum is absorbed partly by the muzzle brake and partly by the recoil mechanism. The original control rod with the recoil cylinder is replaced and tailored with respect to the increased recoil momentum of the heavier cannon. To limit recoil the diameter of the recoil cylinder is increased. The recoil distances have not been changed and are still the same as the original. The original seals are replaced in order to retain the larger fluid pressure generated during the recoil.
As the original two-spring equilibrator is unable to compensate for the increased tipping movement, a new equilibrator has been mounted in such a way that it now houses three nested springs instead of the original two. The new equilibrator reduces the weight moment at all angles of elevation.
The cradle system does not need to be changed, although a small modification is required in order to connect the new equilibrator. No modifications are required to the carriage of the M101. A small reinforcement on the drawbar connection of the trails is required as well as reinforcement of the trails.
The original M101 howitzer provides for a maximum elevation of +65°, but in order to increase the overlap in ranges the original elevation arc has been replaced which allows elevation to +70°.
RDM/Royal Ordnance teaming
Early in 1994 it was announced that Royal Ordnance of the UK had teamed with RDM Technology to offer a number of upgrade packages for the 105 mm M101/ M101A1 towed howitzer.
Marketing lead for projects will be undertaken by either country according to perceived strength within any given market. Generally, Royal Ordnance will be responsible for the ordnance and RDM Technology for the carriage.
The original RDM upgrade, and the one selected by Canada, uses a 105 mm 33 calibre barrel, but now an additional two upgrades are being offered, one with a 30 calibre ordnance which is compatible with the Royal Ordnance L119 Light Gun and the second with a 37 calibre ordnance which is compatible with the Royal Ordnance L118 Light Gun.
The105 mm 30 calibre allows the standard US family of M1 ammunition to be fired to a maximum range of 14,200 m, or using the M913 rocket-assisted projectile a range of 19,500 m can be achieved. Firing the Eurometaal ERM1 (Extended Range M1) base bleed projectile a range of 18,500 m is achieved.
The 105 mm 37 calibre version allows a standard RO L31 high-explosive projectile (originally developed for the Abbot self-propelled gun) to be fired to a maximum range of 17,200 or 20,500 m with an extended range high-explosive projectile.
The RO L31 high-explosive projectile has 25 per cent greater lethality than the old M1 which was developed many years ago. The 37 calibre version has a larger 5 litre chamber which gives a stretch potential for new ammunition in the future.
The prototype of a Brazilian 105 mm M101 system upgraded to the M101/37 calibre system has now been successfully demonstrated with 100 rounds being fired, including Abbot charge super at high temperature.
Full inspection after the UK trials revealed no strength problems and the muzzle blast overpressure was acceptable.
Late in 1997, Royal Ordnance Nottingham was awarded a contract for an undisclosed amount by FAMAE Ordnance Ltda of Chile for the supply of a large number of upgrade kits forthe old US supplied 105 mm M101 towed artillery systems deployed by the Chilean Army.
This is the first upgrade contract for which Royal Ordnance has been selected as prime contractor since signing the co-operation agreement with RDM Technology of the Netherlands covering the joint marketing of the RDM designed upgrade.
Under the terms of the contract, Royal Ordance will supply the 105 mm 33 calibre barrels to RDM Technology, the main subcontractor, who is supplying the other parts including new muzzle brake and breech ring, larger capacity equilibrators, new metering and recoil rod in the recoil system and new seals, replacement of the original elevating arc and reinforcements for the draw bar and trails. The first six complete kits were sent to FAMAE late in 1998, who will upgrade the actual weapons under the supervision of staff from RDM Technology. FAMAE will also supply some components for this upgrade. Once the weapons have been assembled and tested FAMAE will deliver them to the Chilean Army.
The upgraded M101 fitted with a 33 calibre barrel will fire a standard High Explosive (HE) M1 projectile to a maximum range of 11,900 m, or an Extended Range M1 (ERM1) projectile with R0663A2, zone 2 charge, to a maximum range of 19,200 m.
Barrel length (calibres)
Firing range (m)
M101 quantities:
Qnt:
Recon Optical Awarded Contract for Stabilized Remotely Operated Weapon Systems (04.01.2007)


Recognizing the need for good stewardship of the parish community's resources, the Church mandates that each parish have a finance council to advise the pastor on the proper maintenance and development of parish financial resources. The council makes suggestions on how best to utilize, protect, and invest parish funds. They also review and approve the annual budget of the parish.
The council meets at least three times a year to monitor the financial matters of the community and to make recommendations for the future. Members are appointed by the Pastor and serve for a three-year term that is renewable.
The Finance Council at Saint Paul Catholic Church invites you to consider a new way of giving your offertory to the parish by tithing online. You and the parish benefit with this program. Making sure your contribution is made automatically each week or month eliminates the minor frustrations of writing frequent checks or forgetting the checkbook. The parish benefits from a consistent and predictable cash flow and less paperwork.


text:
Q: When does browser delete HTML5 Web Storage data? I'm using for a project the HTML5 Web Storage, and I need to keep the values forever. These are the functions that I'm using:
localStorage.setItem("data_name" , "value") ;
localStorage.getItem("data_name") ;

I'm working on a Raspberry Pi 3 using Chromium browser. Users are not able to do it but, is there any way with which the browser could delete the data? And if yes, how can I completely avoid this?
Thanks in advance

A: HTML5 storage stores data persistently means that it does not expire with a session.If you browse away from the site that saved the data or close the browser, you will notice that the data is still there when you open it again or check for it locally.
If you want to prevent end user from deleting HTML5 storage, Refer below link:
How to Explicitly Request End User to Not Remove Local Storage Data?


EqualLevel's comparison shopping marketplace platform provides a fluid and consistent shopping experience across all sellers, with the ability to compare like products based on price and other attributes. To avoid purchasing incorrectly priced, out-of-stock, or unavailable products, the platform interfaces directly with sellers at their highest level of capability (API, Data Feed, Level II Punchout), ensuring product data is fresh. Contract audit and tracking features ensure shoppers are buying from approved contracts, and are following the correct compliance steps. Everything is captured in the marketplace, available for real-time analytics, and can be archived for up to five years if required by law. Best of all, your marketplace is ready-to-shop in less than 30 days, with zero user training required.
Using our business Network, suppliers with existing punch-out sites can quickly test and submit their punch‐out catalog and order delivery credentials. Once validated, their site is available for buyer acceptance testing and rollout.
EqualLevel provides a no-charge, punch‐out storefront. Sellers can quickly implement a punchout storefront with buyer specific prices, item management, and custom landing pages.
Search multiple approved external sites from one user interface. Now, employees can find anything they need with a single view of search results.
Procurement can monitor compliance against contract pricing of their punchout site. Price discrepancy notifications are automatically sent, and in-process requisitions halted and flagged for review.
With the flexible workflow engine, approval chains can be quickly configured to follow ideal requisition paths for broad visibility and maximized savings realization.
A central location to receive all items with the click of a button, and complete a two or three-way match from a single interface.
Integrating your marketplace with your Enterprise Resource Planning (ERP) can help you maximize your investment. EqualLevel integrates with more than 20 financial systems from familiar market-leading systems to proprietary State sponsored systems.
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When traveling with your spouse, you have to compromise a lot, such that, at times after a visit to one of the best places in the world, you leave with an anti-climax, a feeling that you have not fully absorbed the attractions of the place. Another surprise is that Somalia has not had a functioning central government in over a decade. Then of course we have the wonderful Italian option with Italy being a favorite of many and with cities such as Florence, Venice, Rome and Milan what is not to enjoy. The Nepalese government encourages increased tourism to Everest and Nepal. Oktoberfest is always a popular time to come to German Village.
Udaipur and Jaipur are two most outstanding and beautiful cities of Rajasthan. , Romania Forget about the 21st and 20th centuries and explore this pastoral region of timeless villages, donkey carts, wooden churches, and medieval peasant life. Goa is one of the most popular holiday destinations which draw many tourists from all over the world. A few of the well known resorts are Heritage Resorts, Sneh Resorts and Aravalli Hills Resorts etc. The most important thing for a music travel to be interesting and amusing for you is the choice of destination.
This manmade, 17 mile long, illuminated lake is the largest fresh water SCUBA resort in the world, with visibility of over 100 feet at all times. This attracted criticism, with claims that the film company had damaged the island's environment, an accusation the film's makers contest. Here are a few of the attractions that await visitors to Minnesota:. We will travel to some very well known celestial bodies:. Every part of this city takes you to the new world of enjoyment.
To get information about kindly visit his brand new website about. This made her a world renowned singer and made her attract millions of fans. It was only in 2011 that the state of Sudan finally split apart due to civil war and a new state, the Southern Sudan, was established. Along the Mekong Delta you'll find sleepy villages and incredible fish markets with delicious fresh caught fish. Although Branson is considered a country music destination, all music lovers can find something to sing about in the "live music show capital of the world.
India is the true paradise for the travel buffs, as it offers a diverse range of travel destination. Hike through the region from one eye-popping valley to the next, visiting a wealth of ancient frescoed churches and homes, and relax each night before a majestic sunset over the dizzying landscape. It is a very popular detour from the bustling Buenos Aires. The Champagnes, Red Wines and White Wines served here are some of the best in the country. If you're in the northern hemisphere (where the summer months are June, July, and August), the following travel destinations are great places to go on your summer vacation.
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Environment | News
| Oct 7, 2019 at 12:01 am.
Shell Oil Corporation Burning Gas for Months Because They Can't Sell It
The huge fires can be seen and heard from miles away.
(TT) — The Shell oil corporation is burning off large volumes of ethane because they can't sell it to their regular customer, which is a plant on the same property owned by ExxonMobil. The location is officially known as "Mossmorran," and is used by numerous oil and gas companies. Residents near the property where the ethane is burning are complaining of pollution, light, and noise coming from the site.
Residents were hoping that the burning would only be happening for a short amount of time, but the ExxonMobil plant won't be operational again until at least November. The plant is currently under a construction process that will cost at least £140m and is expected to last through November. Until then, Shell intends to continue the fuel burnings, insisting that they have nowhere to store it and no choice but to burn it.
According to BBC, a Shell Fife Natural Gas Liquids spokesman said, "The (ExxonMobil) Fife Ethylene Plant is currently the primary customer for ethane supplied by the Shell Fife Natural Gas Liquids plant, and processes ethane into ethylene. Our ground flares are burning excess ethane as the Fife Ethylene plant is currently not available for receiving the ethane to process it into ethylene.
"We have taken measures within the North Sea (SEGAL) supply system to help to manage the situation and are actively exploring alternative ethane outlets during the temporary shutdown. However, the volume taken by the Fife Ethylene plant is significant and any solution is likely to be for some volume rather than the full volume of ethane the Fife Natural Gas Liquids plant produces," the statement added.
The burns have been going on for months and making life horrible for the surrounding community. However, the site has been a point of frustration for locals and environmental activists for many years, because this sort of activity is unfortunately extremely common.
Residents have posted videos to social media, showing how the fires from the plant light up the sky at night.
Very loud and unsettling noise from mossmorran tonight 😔 #Mossmorran pic.twitter.com/neoeL2KDQH
— Danni JP Newlands (@ProctorDanni) April 21, 2019
The company insists that the fires are safe and heavily controlled, but the entire surrounding area is very concerned about their health and safety.
All safe is it? Nothing to worry about they say?#mossmorran pic.twitter.com/4YVgF2um6U
— claire graham (@cg19801) April 24, 2019
The fires can be seen and heard from miles away.
@exxonmobil_fep want to sleep but cant because #mossmorran is so loud maye may not sound like it but so loud pic.twitter.com/KRKBqiaTmr
— annabel murphy (@AnnabelMurphy95) April 23, 2019
The Scottish Environment Protection Agency has received at least 1,400 complaints this year relating to the site, most of which are from local residents concerned about their health and well-being, according to BBC.
James Glen, chairman of the Mossmorran Action Group, said that his organization has received hundreds of reports from people concerned about their health.
"People are suffering breathing difficulties, headaches and sore eyes but they are also concerned about rare cancers rates as well as common cancers," Glen said.
There are also many children with asthma in the area, who end up having increased difficulty breathing on days when the burns are stronger.
Things have gotten worse than ever at the site since Shell has begun burning such large volumes of ethane, but pollution, loud noises and flashes of light throughout the evening is common for the area. When the ExxonMobil plant is fixed, many of these problems will continue to persist, but likely won't be as bad.
By John Vibes | TruthTheory.com | Republished with permission
The views in this article may not reflect editorial policy of The Mind Unleashed.
Bizarre | News
| Jan 21, 2020 at 10:31 pm.
John Vibes
Furries to the rescue!
Awareness | News
Free Thought Project
Plot twist: The biggest threat to police are themselves.


I received an invitation this morning to the opening of Joan Sallas' "Gefaltete Schönheit", an exhibition of folded napkins. I shan't be attending, but it looks very impressive. If you're anywhere near Vienna, try to see it.


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« 8. TRUST ME COMMODITY
10. CH-CHING »
9. LISTEN UP
8 am. Wednesday 21th October 2048.
McGuire Management Corporation's conference hall, 53rd at Third, Manhatton.
Mark McGuire comes to the podium. In front of him several hundred media personal. On the walls and on the ceiling, several thousand media companies are linked in virtually. This broadcast will immediately reach eight billion people.
[Mark McGuire]:
"Welcome ladies and gentlemen. A fabulous New York morning welcome to you all. First, thank you all very much for coming at such short notice. Apologies for the slight delay. Last minute clarifications as always. Hopefully, we've been able to keep you all fed and watered. And…. Well let's get into it.
Let me take a moment to acknowledge that this world is a very different and a much better place in 2048 than it was just thirty years ago. As a result of our global political unity the number of murderous conflicts has dropped to a tenth that of the early 21st century. Our actively promoted, and generously funded, Global Interdependence Initiative has resulted in major scientific and medical breakthroughs. Ladies and gentlemen, our kids, all of them, get better education, better nutrition and better mentoring than even the most privileged nations and families could earlier provide. We have so much to be grateful for. Thank God. Or thank goodness.
Of course, challenges remain and new challenges arise. There will always be challenges. I'm confident that we'll meet them head on and collaboratively just as we have being doing so successfully. And success breeds success. By remembering what's been done, and how, and with what fortitude and inspiration, well, we'll have the right thinking and implementation tools to provide a better and better platform for humanity, for our humanity, to shine in the sun.
Let me briefly remind you of one of the remarkable episodes and certainly the most remarkable personality that got us to where we are today."
McGuire signaled, the room darkened and a video clip started to play. It was from a very famous 2025 broadcast of Channel V's 'John Cole Consults' current affairs program. The program had been filmed at the White House and included the host John Cole, President Colin Hohenstern and Layla.
Amazingly, this was the first time Layla had set foot in America. The American people, who had only witnessed Layla's sensational feats second-hand through the media, carpeted Dulles airport a million deep which was quite a sight. John Cole had just introduced the President and Layla in suitably deferential terms.
[John Cole]:
"Mr President, concerning the proposed military escrow arrangement, is the US likely to agree to it, if so when and, if not, do you have alternative proposals?"
[President Hohenstern]:
"America supports, and is greatly encouraged by, the recent work done on national demilitarization within Europe, China and Asia. We feel that we are all moving in the right direction for greater peace, trust and cooperation.
We believe great caution and surety of step is now required. We love the concept of the military escrow, a smooth transition and accumulation of military personal and technology to a trusted third party who then cedes to the globally agreed institution.
What we say though, is that yes we love the concept, we are happy with the concept but now, as we think about implementation, we need to apply risk management to it. America has invested heavily in thinking about how we can make this work. The best solution is for the American military to be the 'escrow' institution. We have most of the military resources already so that cuts down the cost and risk of failure enormously – less transition and accumulation and little need for final handover. Additionally, we show a good record of not abusing our military strengths over the last century. John, we haven't tried to take over the world despite being able to. It's part of our national character to value freedom and democracy."
"Layla, the US preference for being the provider of 'global military services' to a 'yet to be elected' global government has been a deal-breaker so far. Is it an insurmountable problem or do you think an agreement can be reached?"
[Layla]:
It is essential that the military aspect of the global government reports directly to it. An outsourcing option is not possible. An important aspect of the escrow plan is to do with the unbundling of current internal national power structures and the rebundling of their resources into structures that consistently support a varied military capability within a single global authority. True, the same sort of checks and balances that are found within the American military are required at the global level. However, the decision concerning the funding of the military must rest globally and that's impossible if America becomes a monopoly supplier. Indeed the invocation of client/supplier service provision terminology is not relevant here. Remember it is likely that the size and cost of the military will vastly decrease over time. That will positively impact on the whole population. If America is being paid to maintain and run the global military then it's unlikely to want that payment to decrease and, if pushed, would have the military strength to back itself up in negotiations. No, that's not what is wanted at all.
"With the greatest respect Layla, America has by far the most experience of handling complex military operations. We can't throw out the baby with the bath water. Equally, the risk to America posed by an immature organization holding the military button is far too high for any President to accept so…"
"You are not listening Colin."
Layla abruptly jumped up from her seat stomping her right foot, clapping her hands and shouting 'Now listen' simultaneously.
Layla's unexpected offensiveness caused mayhem among the secret service agents arranged off-camera. As the president lurched back as if shot, the ten agents had already scrambled as if off a starting block. Six got to and covered the president, two covered a panic-stricken John Cole, two aimed and fired at Layla in an attempt to 'put her down'. She didn't go down. she stood her ground, unimpressed. The covering agents were furiously looking around for movement, looking at the camera operators, at the other crew members, at Layla and, in absolute disbelief, at their two colleagues standing acquiescently near Layla.
As the 'looking about' frenzy ebbed, Layla walked very close to President Hohenstern and, through a heap of agents, quietly said "I look forward to meeting with you in Melbourne next week". Then she walked out of the studio, not dead, not injured, not ruffled and not followed.
The president was attended to. He was blind and dumb but his hearing was fine. He insisted that no-one impede Layla's leaving of America (in writing!). And, as history recorded, he made a full recovery on the flight home from Melbourne.
The video clip ended.
"Yes, you just can't tire of that eh? Anyway, this brings me to why we're here today. Three years ago, beautiful Layla, incomparable Layla, blessed Layla left. In what way and under what circumstances, no-one knows. Layla, who peeled the bitter skin from our planet to give us the sweet juice inside, is no longer available to give us further perfect encouragement. It's been a period of grieving for most of us that is only now turning to acceptance. Yes, we all remember her and will never forget. Hers was a miraculous life well documented in articles, programs and interviews. Even with all that we want more. Ladies and gentlemen, we have more!
In ancient times, the divine knowledge and the actions of prophets were passed down through generations via oral tradition. More recently we have written accounts by the prophets themselves or their followers.
Today, just starting today, well just made public today, the life of Layla Parkin is documented on…. digital video."
The media people were a little perplexed. What was McGuire ranting on about? McGuire let the perplexion simmer for a while.
"Yes, I mean what I say. The excerpt you have just seen did not come from any previously recorded public or private media materials. It couldn't have! Let's just play a bit of it again. And without the audio please guys. That's it. Where do you think the camera is?
I'll tell you where it seems to be. Two metres in front of the host, Layla and the President. And no, there's no zoom. Here's why. Look, our 'camera' has turned around and is recording the secret agents running past those Channel V cameras and now, the agents are running through our 'camera'. Okay, stop it now guys and run the Channel V feed.
Okay, with the Channel V feed you can see it appears further back, but of course that could be manipulated, and… there go the agents past Channel V cameras and …. no other camera, nothing. Empty space. That's right folk. Believe me. Go check your own archives.
Ladies and gentlemen, a McGuire Management Corporation client has received a digital recording of the life of Layla Parkin. The method of recording is definitely – Not Of Our World.
Our client is staggered and very humbled at being selected to be the recipient of this important testimony and believes it only right and proper that it be shared with the whole world as soon as possible. Right now McGuire Management Corporation is very privileged to be assisting our client with locating appropriate distribution partners. We are currently talking to a number of interested parties and we will release updates as negotiations conclude. This is a momentous day and this is the end of our announcement. Thank you, everyone, very much and I'll take a small number of questions now. Yes, Keith?"
"Yes, Keith Woodfeld, CNN. Mr McGuire, who is your client and how did they come into possession of this footage?"
"Keith, my client wishes to remain anonymous and, quite correctly I believe, feels that attention is much more deservedly turned to this repository of Layla's life than to themselves, the temporary trustee. I am unable to go into details about the circumstances of procurement. However, my client has confirmed that no laws were broken and all was very much above board."
"Anna Griel, Reuters. Mr McGuire, you mentioned you are talking to distribution partners. Who are they and just how much money are we talking?"
"Yes, Anna – I am unable to discuss the details of our ongoing negotiations at this point. However, concerning money, believe me, that's not relevant here. By far the biggest motive our client has in this matter is to ensure that everyone on this planet has an opportunity to gain access to this fantastic treasure. Our client has acted with tremendous foresight in appointing McGuire Management Corporation. Our terms of reference are to manage the process of gathering a team of distribution partners whose infrastructure capabilities synergize in order to gain access to every single person in the most effective way for that person.
Of course there is a cost to all of this that needs managing and MMC will, of course, pay careful attention to all matters fiscal. Our client though, as mentioned, has pure motives.
Indeed, our client has indicated that a generous slice of any monies received will be immediately directed to charities and good works as Layla would surely have wanted."
"Ayesha Hassan, Al Jazeera. Mr McGuire does this recording show what happened to Layla Parkin and if she is still alive today?"
"Great question. I have talked about the need for distribution partners. What I haven't yet put into context is the sheer enormity of the logistics associated with this exercise. It's a large part of the reason that a mix of distribution partners with far reaching resources is necessary. First, Ayesha, let me say that the first question off my bat was the same as yours. The initial information given to me was that it probably does not show what happened. I say probably because we are not positive on that yet and our technical folks are still working on it. What we are sure about, and listen up folks, is that this starts at conception, yep conception, and goes for about sixty years. This isn't a trailer. Or a series of seminal moments. This is an epic. We have about a hundred people scanning and cataloging right now and we haven't touched the edges.
Okay everyone. That's it for now. Again, thanks for coming. Enjoy your day."
Posted in america, global government, media, military, press conference, washington, white house |


A local 80's station has arrived to help me skip along the path down memory lane. While driving home from the airport Friday night, I heard "I Still Haven't Found What I'm Looking For," "You're One of My Kind," "Major Tom (Coming Home)" and "Lonely Ol' Night," just to name a few.
Of course, yesterday while driving to the market after church with the family, I absent-mindedly switched on the radio, typically parked at NPR, only to quickly turn it off again. Billy Idol just wasn't the tone I was looking for.
NPR?? What? You like to get mad?
RWS- I listen to NPR because I like to have my mind sharpened, so to speak. I want to shape and form my own opinions rather than vomit up the ones feed by conservative talk show hosts. That's not to say I disagree with the conservatives at all; I just want to know why, and what I am specifically disagreeing with. As we listen, I will tell the girls why I disagree or how the perspective presented is being skewed to fit the ideology or to lead the listener to a certain opinion. I will explain the flip side or proper way to examine statistics and maybe say what isn't being said by the speaker.
I also do like the cultural pieces that NPR produces, as do my girls.
I think you mean "Need You Tonight," assuming we're thinking of the same INXS song. I used to love me some INXS and then Michael had to go off himself in such a strange way.
As for NPR, I too enjoy it from time to time, particularly "All Things Considered." Those who avoid "the other side" gain nothing by living in an echo chamber, other than a myopic worldview.
I am so cultured! I listen to NPR because they don't have that annoying morning banter that makes me want to rip someone's head off and... ok, deep cleansing breath, Mountain Pose.. there, much better.
Now see, I was coming in here to say, it's "Need You Tonight" by INXS, because even though Michael Hutchence looked like Justine Bateman, he still deserves correct song title quotations. :-) But Andy up there beat me to it.
The 1967-1979 and the pre-1967 lists aren't nearly complete yet. :-) Nice blog!
Kim- thanks :D Another 80's afficonado? Woo-hoo.


text:
Police Abuse, Misconduct, Negligence
Forums > Incidents and Discussions > Other News Feeds > Police Misconduct >
"Serious social unrest is coming in the next 5-10 years in this country as the police state gets dialed down."
National Police Misconduct NewsFeed Daily Recap 04-18-13
Discussion in 'Police Misconduct' started by CATO Police Misconduct, Apr 19, 2013.
CATO Police Misconduct News Feed
Here are the 8 reports of police misconduct tracked for Thursday, April 18, 2013:
Dallas, Texas: A police officer [Nicole Thomas] has been suspended with pay after she was arrested for drunk driving. She is now on administrative leave. ow.ly/kcE2S
Eureka, California: A police department sergeant [Adam Laird] was arrested following allegations of excessive force by a fellow officer and accusations he filed a false police report. "We will not tolerate misconduct by any of our officers, and I firmly believe and stand behind that Police Officer's Code of Ethics, that each of our officers are expected to conduct themselves under that code," said the police chief. ow.ly/kcswp [in a separate case, previously found liable in the death of Martin Frederick Cotton II, 26]
Martinsburg, West Virginia: The former sheriff [Robert "Bobby" Shirley] will face a sentencing hearing. He has pleaded guilty to charges of using excessive force under color of law for the beating of a since-convicted bank robber [Mark Daniel Haines]. The man suffered a broken nose, a broken jaw, a broken eye socket, and other injuries. ow.ly/kcegQ
Edwardsville, Illinois: The police chief [James Bedell] pleaded guilty to federal charges and admitted stealing roughly $138,000 from the city. He took cash and money orders from a department lock box that contained vehicle impound fees. "I am disgusted and saddened when called upon to prosecute someone who had sworn to uphold the law," said a U.S. attorney. ow.ly/kccVV
Dekalb County, Georgia: A police officer [Scott Biumi, 48] who was waiting in the drive-thru line at a McDonald's is accused of pulling a gun on the customer [Ryan Mash, 18] ahead of him because the officer was angry at having to wait for his food. "I'm just not going to stand for any behavior that goes outside that scope of the law," the chief said. An investigation is underway. ow.ly/kc2Ue
Denver, Colorado: An officer [Michael A. Samuels] has resigned. He has been accused of working another job while simultaneously collecting workers compensation payments. ow.ly/kbDKi [Other recent resignations: Lt. Tim Rusk retired following a DUI arrest, Officer Jairon Katz resigned as he was being investigated for having sex in a patrol car and Officer Scott Kida resigned during an internal affairs investigation of inappropriate conduct in dealing with a female victim in a domestic violence incident]
Charleston, South Carolina: A former police trooper [John Sawyer] pleaded guilty in federal court to using excessive force when he repeatedly kicked an arrested man [Sergio Caridi] in the head and neck following a high speed chase. ow.ly/kaNRa
New Orleans, Louisiana: An officer [Desmond Pratt, 42] was arrested and booked with forcible rape of a 15 year-old girl. He was also booked on charges of sexual battery, and was immediately put on emergency suspension without pay following his arrest. The officer was given a $50,000 bond during a hearing. If he makes bond he must also wear a monitoring device and avoid contact with the victim. ow.ly/kbVb7
National Police Misconduct NewsFeed Daily Recap 04-18-13 is a post from PoliceMisconduct.net
CATO Police Misconduct, Apr 19, 2013
Tags: Dallas, Texas, Nicole Thomas, Eureka, California, Adam Laird, Martin Frederick Cotton II, Martinsburg, West Virginia, Robert "Bobby" Shirley, Mark Daniel Haines, Edwardsville, Illinois, James Bedell, Dekalb County, Georgia, Scott Biumi, Denver, Colorado, Michael A. Samuels, Lt. Tim Rusk, Officer Jairon Katz, Officer Scott Kida, Charleston, South Carolina, John Sawyer, New Orleans, Louisiana, Sergio Caridi, Desmond Pratt
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text:
Families of Spinal Muscular Atrophy and Repligen partner to develop a treatment for SMA
Families of Spinal Muscular Atrophy (FSMA) announced today that it has entered into a groundbreaking exclusive license agreement with Repligen Corporation for the development of a potential treatment of Spinal Muscular Atrophy (SMA).
SMA, the leading genetic killer of children under the age of two, is typically marked by the degeneration of muscle movement including the muscles that control crawling, walking, swallowing or breathing. There are no approved therapies for the treatment of SMA, which affects one in every 6,000 babies. One in every 40 people carries the gene that causes SMA, indicating approximately 7.5 million carriers in the United States.
Families of SMA was started by a small group of parents in 1984 who wanted to raise funds for SMA research and support all affected families. FSMA has funded $50 million for SMA research, raised from individual donations and through fundraising events held by volunteer families and Chapters.
Overactivation of neuroimmune gene leads to schizophrenia-like changes in mice
Post-mortem genetic testing used to find underlying cause of sudden deaths in Amish families
The International Consortium Claims Medical Breakthrough in Malaria Research
FSMA made investments of $13 million during the last decade to bring this specific program to the cusp of clinical development. Through FSMA's leadership, the research has resulted in a drug candidate that treats the underlying cause of SMA. In preclinical studies, the drug has been shown to efficiently cross the blood brain barrier - a critical feature for a neurological drug - and prolong survival significantly in two different mouse models of SMA.
Often an "Orphan Disease," such as SMA, will not be "adopted" by the pharmaceutical industry because there is limited financial incentive to make new medications to treat smaller patient populations. This license agreement marks a significant milestone for the SMA community by securing the commitment of an industrial partner to develop potential treatments through the highly expensive human clinical trial phases.
"At this point in the program, joining forces with a corporate partner to advance into clinical studies is the best way to meet our objective of accelerating drug development for SMA," said Kenneth Hobby, President of Families of SMA. "Repligen is an ideal partner for this program with the necessary resources and expertise to invest in and focus on successfully developing this new treatment for SMA. We are very excited to partner with Repligen and look forward to making our combined efforts successful in delivering an effective treatment to our patients."
"Families of SMA has made remarkable progress in defining a series of highly potent compounds which may be clinical candidates for SMA," stated Walter C. Herlihy, President and Chief Executive Officer of Repligen Corporation. "We look forward to working with FSMA and their collaborators in the development of what we hope will be an important new treatment for SMA."
Through the agreement with Repligen, Families of SMA has the potential to recover its investments through a series of milestone payments if the program successfully progresses through clinical stages and eventually reaches market approval.
Families of Spinal Muscular Atrophy
Tags: Blood, Brain, Breathing, Children, Clinical Trial, Gene, Genetic, Muscle, Muscular Atrophy, Nervous System, Pharmaceuticals, Preclinical, Research, Spinal Muscular Atrophy, Swallowing, Walking
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One-fourth of children with autism miss diagnosis, study finds
Avacta and Daewoong Pharmaceutical announce joint venture to develop novel cell and gene therapies
Scientists identify 'modifier gene' that determines severity of inherited kidney disease
Judo holds promise for reducing sedentary behavior among children with autism


Hello, amn't I a blast from the past?
Hope you are well. Strange that it can be so easy to fall out of a good habit and almost impossible to get back into one. Over the year I have often thought about writing on this blog and sharing some my photos from my less frequent rambles but somehow I just never did. Many times I started, but I just got lost in the photos or daydreams but today is different because here I am!
Over the next few weeks I'll share a mixture of posts from the past year. Most of my mini adventures have been in Australia, Queensland and Tasmania predominately – this country is simply too big to see everything. I'll also share some more about my time in New Zealand at Easter… here's a few to get us reaquainted.
Hi, somehow I am only seeing this now! thanks 🙂 have been out and about a little more recently so there's a few more coming your way.


No matter how it starts, however, it always ends the same. Remember, it's a slippery slope from a questionable infringement justified in the name of safety to all-out tyranny. These are no longer warning signs of a steadily encroaching police state.
We have moved beyond the era of representative government and entered a new age. You can call it the age of authoritarianism. Or fascism. Or oligarchy. Or the American police state. Whatever label you want to put on it, the end result is the same: tyranny.
There were four armed police officers, including one cop who was assigned to the school as a resource officer, on campus during the Florida school shooting. All four cops stayed outside the school with their weapons drawn (three of them hid behind their police cars). Seventeen people, most of them teenagers, died while the cops opted not to intervene. Let that sink in a moment.


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CREATE Ghana is an enterprise development organization focused on enhancing the practice of entrepreneurship in Ghana.
We recruit and coach aspiring entrepreneurs and connect them with a dynamic ecosystem enabling access to finance, markets, and talent. By working with experienced professionals to define and validate compelling new ventures, we create the foundation for building sustainable, scalable businesses that provide attractive employment and investment opportunities.
CREATE VENTURES. CREATE JOBS. CREATE FUTURES.
We are committed to building a new generation of skilled entrepreneurial leaders in Africa.
We focus on cultivating businesses in vital economic sectors including agribusiness, manufacturing, energy, sanitation, and education.
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BUILDING AN ECOSYSTEM. ONE PARTNER AT A TIME.
We partner with like-minded organizations to foster a thriving entrepreneurial community.


Armed police followed a convicted Huddersfield drug dealer for almost 120 miles before stopping his Jaguar in Moldgreen.
Surveillance officers from the National Crime Agency watched 33-year-old Zahid Ali talking with an a criminal associate in a Coventry car park on June 11 this year.
A team of armed officers followed Ali north on the M6.
They stopped his vehicle and arrested Ali at traffic lights on Wakefield Road, Moldgreen. A round of ammunition was found in his jeans wrapped in tissue.
At the time of his arrest Ali, of Newhouse Place, off Highfields Road, Huddersfield, was on licence after being released early from an 11-year sentence imposed in 2011 for storing an "arsenal of weapons" which included a de-activated Uzi sub-machine gun and three semi-automatic handguns – and class A drugs.
He has now been sent back to prison and could have his sentence extended after he pleaded guilty alongside Fitz O'Brian Mahoney, 39, of Coventry, to four firearms offences.
Both had previously been convicted of possessing firearms and ammunition and were on licence at the time of their arrest.
Ali appeared at Leeds Crown Court this week and admitted possessing one round of ammunition without a certificate.
Mahoney pleaded guilty at Birmingham Crown Court to possessing ammunition without a certificate, possession of a firearm when prohibited for life and possession of 10 rounds of ammunition when prohibited for life. A 35-year old man, arrested at the same time as Ali, has also been recalled to prison after breaching the terms of his conditional release. Sakawat Shah, from Cloudsdale Avenue, Bradford, was convicted in October 2011 for conspiracy to possess and possession of a firearm with intent and will now serve the remainder of his eight year sentence.
Mahoney and Ali will be sentenced on September 28 at Leeds Crown Court.
Mark Spoors from the National Crime Agency said: "Both Ali and Mahoney had been released early from prison, yet continued to commit serious crime with blatant disregard to the impact on their communities.
"They have been sent back to prison to serve the remainder of their sentences. Working with West Midlands Police and West Yorkshire Police, I believe we have stopped two career criminals who would have carried on selling and transferring firearms and ammunition.