text:
> Celebrity News
Harry Styles, Liam Payne and Simon Cowell break silence on Zayn's One Direction departure
March 26, 2015 - 11:16 GMT hellomagazine.com Harry Styles, Liam Payne and Simon Cowell break silence on Zayn's departure from One Direction
Harry Styles and Liam Payne spoke out for the first time following Zayn Malik's shock departure from One Direction on Wednesday. Harry was the first band member to tweet, writing simply to his 24.1 million fans: "All the love as always – H."
A few hours later fellow bandmate Liam also posted a message: "So glad to be in bed after a long and strange 24 hours."
While Louis Tomlinson remained quiet on the social media front, Niall Horan shared with fans that he was unable to sleep.
Harry and Liam wrote on Twitter following the unexpectated departure of their fellow bandmate Zayn
Simon Cowell, who formed the group after the boys had auditioned separately on X Factor in 2010, reassured distraught fans that the band still had a bright future ahead.
"Sometimes strength is not defined by numbers," he wrote, before continuing: "As always you the fans have shown your amazing support to all the boys. When you have great talent great things happen."
The music mogul signed off for the day with: "Goodnight everyone".
Simon Cowell founded the band in 2010
Zayn announced he was leaving 1D after five years via an unexpected message on the group's Facebook page. The statement said: "My life with One Direction has been more than I could ever have imagined. But, after five years, I feel like it is now the right time for me to leave the band.
"I'd like to apologise to the fans if I've let anyone down, but I have to do what feels right in my heart. I am leaving because I want to be a normal 22-year-old who is able to relax and have some private time out of the spotlight.
Harry broke down in concert in Jakarta, Indonesia
"I know I have four friends for life in Louis, Liam, Harry and Niall. I know they will continue to be the best band in the world."
Emotions were running high, as just hours before the statement was released, Harry broke down in tears on stage after the remaining boys had performed in Jakarta, showing that the band knew of Zayn's decision.
Here's why you should light that gorgeous candle now - don't wait!
More about harry styles
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Harry Styles sells his LA home at a £500k loss – take a peek inside
Harry Styles breaks down in tears as One Direction carry on with the show
Zayn Malik leaves One Direction after five years
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Chief executive Gillian Donaldson is leaving Morton.
MORTON's chief executive Gillian Donaldson has left the club.
A statement from Cappielow confirmed her departure after 15 years of service.
It said: "It is with regret that our chief executive, Gillian Donaldson, has tendered her resignation with immediate effect.
"Gillian, who has been a family friend of the Raes since her schooldays, advised the chairman at the start of the week that it was her intention to leave and take her career on a different direction.
"Everyone at Greenock Morton wishes Gillian all the very best in her new career path and thank her for her devoted service, helping to take the club out of administration 15 years ago.
"Gillian who was one of the youngest bank managers for Royal Bank of Scotland before joining the Club in 2001 has been a fantastic servant to GMFC and will be sorely missed by all her friends and colleagues at the club, the SFA and the SPFL."


Running a business of any size is no easy task, there are so many variables and risks involved it's no wonder that over 30% of businesses fail within the first year. In order to give your business the best opportunity for success, you have to employ a sound strategy in all divisions of labor—sales, marketing, purchasing, customer service, and many other departments.
The one area where many companies hit a speed bump is in marketing—and rightfully so with all of the complexities that envelop creating a sound marketing strategy. Most companies will hire outside consultants from a reputable digital marketing agency to help develop and manage their marketing and SEO to cut down on payroll while getting dedicated expert help.
In fact, 62% of companies in the U.S. alone outsource their digital marketing—it has many attractive advantages but there's a caveat with outsourcing if you aren't careful. So when choosing a digital marketing agency in Houston to handle your digital marketing and SEO, make sure you don't make one of these top 5 mistakes that can cost your company clients as well as millions in losses.
This is actually a far more common mistake than you might think—but in reality, it's an easy mistake to make. If you are familiar with the saying, "Believe none of what you hear and only half of what you see," then pay attention and believe this.
One of the biggest misconceptions about digital marketing agencies is that if they present an amazing marketing pitch for you with fancy charts, high-tech terminology, and beautiful graphics and video—then this is the same service you will get for your customers.
Let Us Burst That Bubble Right Away—That's Not Usually The Case.
SEO agencies that put a lot of money and fluff into their sales presentations typically won't give you, the customer that same effort and energy. Nevermind the cool promos, video presentation and Powerpoint shows—logic it out. Every organization is going to have limited amounts of resources, so how they spread those resources around gives you a clue about their priorities.
If a company spends more money on sales staff than they do on account services, that tells you they're focused more on sales than on servicing their clients. That is a big red flag right off the bat and is a sign that they are a company that talks a good talk but doesn't back it up. You want a company with a balanced focus otherwise you're just another number.
For example, at SiteJab our salesforce is actually the smallest department in our agency while our account advocates, social media management and content creation teams comprise the majority of our workforce. Why? Because we seek out clients that match what we are looking for in clientele. We build relationships with our clients so we focus on the quality of clientele vs. quantity. We want to make sure that we have clients share values that we can personally be vested in. That being said, our advice? Choose the agency where service is evidently the backbone of the agency. Don't get sucked into jargon-filled pitches that are all fluff and no substance. Real SEO agencies speak in transparency and know that we know nothing more than you can learn with some research. We just know you want to spend your time on what you do best—running your company and let us handle what we do best for you.
Rolling right along from the first mistake, this one is tied closely to it. If you have a digital marketing agency that has promised you the benefits of their "exclusive SEO secrets," or "proprietary algorithms"—throw their card in the trash right away. Why?
They are just flat out lying to you. It's not creative wording, it's not branding—it's just lying and if there is one thing we hate about the SEO industry—it's some of the dishonest tactics some companies employ to grow business.
The processes and strategies of SEO are thoroughly documents and understood by multitudes of experts around the world. SEO is not rocket science but it does require a lot of analysis, time-consuming optimization and acute attention to details. The only difference between having an effective SEO campaign and a broken one is your strategy and execution of common knowledge concepts.
The old adage rings true: "If something is too good to be true, it's probably a lie." So don't fall for an SEO agency in Houston that puts on a magic show —the only thing that they can make appear out of thin air is a hefty bill. Find an agency that shows you a proven track record with honest principles—that's where the magic happens.
When it comes to digital marketing in Houston, you get what you give—hands down.
Sure you can choose from the gamut of fly-by-night SEO agencies that offer their services for as low as $99.00 a month—but are you even getting $99.00 worth of quality SEO work?
In fact, you may actually end up doing more damage than good as most cheap SEO agencies use tactics that are penalized by Google. Search engines including Google have known about exploits and shortcuts to try and manipulate search results and they catch hundreds of sites per day utilizing those tactics.
When Google penalizes your site, you might as well kiss your traffic goodbye—literally. Google takes search engine manipulation attempts very seriously and has a zero-tolerance policy. They have the power to make your site disappear in search results.
So the lesson here is: Cheap is never good and good is NEVER cheap. If you can't afford a digital marketing agency's service that you like, at least ask if they do consulting so you can make sure you aren't unknowingly doing damage to your business with bad tactics.
We're not against supporting local businesses, not at all. However, in choosing a digital marketing agency, you shouldn't feel geographically limited. A good agency can be found 10 miles from your business or 100 miles from your business—it won't affect their ability to deliver quality SEO solutions. The awesome thing about the web is that it is accessible from anywhere and can accommodate virtual meetings as well. While it's true that face-face interaction is important in business dealings, an agency should care enough about your business to come to you. SiteJab regularly invests in sending our account advocates to our clients anywhere in the US to discuss their projects.
Now with that being said, you still want to keep your SEO business stateside. Sure you can buy really cheap digital marketing bundles from "SEO click farms" overseas and "agencies" but this will more likely damage your company than help it.
Even if the company is legitimate, it's the cultural nuances and slang that must be understood thoroughly to translate into content and online articles. You need the tone and language to sound natural and unfortunately, that is never guaranteed with foreign companies.
Listen, SiteJab didn't earn Google Partner status by not knowing SEO inside and out. We build relationships with our clients that last for years.
When it comes to producing the numbers—our track records speaks for itself. Contact one of our business consultants and let's talk about what SiteJab can do for you.


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Northeastern US: Fewer thunderstorms to come at price of increased cooling costs this week
By Kristina Pydynowski, AccuWeather senior meteorologist
June 24, 2019, 12:49:46 PM EDT
The northeastern United States will not face another onslaught of downpours despite showers and thunderstorms returning this week, but residents will be cranking up air conditioners more than in recent weeks.
An end to the nice weather across the Northeast will come early this week, with showers and thunderstorms forecast to be present across a part of the Northeast each day this week. However, not every community will receive rain on a daily basis.
That is definitely good news for farmers waiting for fields to dry out, construction crews looking to get projects done and anyone else with outdoor plans.
"High pressure will begin to move out of the Northeast on Monday, but Boston and the rest of New England and upstate New York will stay dry and pleasant," according to AccuWeather Meteorology Intern Adam Sadvary.
"Those planning on spending time outdoors in New York City or going to the game between the Yankees and the Toronto Blue Jays in the evening should not worry about seeing any showers," Sadvary stated.
New York City, however, will join all of the mid-Atlantic in turning more humid on Monday.
Woman captures chance photo of rare, mesmerizing cloud phenomenon and attracts waves of interest online
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Men vs. women: Which gender is more likely to be fatally struck by lightning?
Atlanta to Pittsburgh, Detroit at risk for severe weather into Monday night
A stray thunderstorm may rumble over Washington, D.C., and Baltimore on Monday, but places along and west of the Appalachian Mountains may face the stormiest conditions.
Pittsburgh and Erie, Pennsylvania, will be among the communities across the eastern Ohio Valley and northward to around Lake Erie at risk for downpours and severe thunderstorms on Monday and Monday evening.
Rain and thunderstorms will continue to advance across the Northeast Monday night into Tuesday.
"Thunderstorms can still produce gusty winds as they track across the rest of Pennsylvania and the southern tier of New York on Monday night and into early Tuesday," according to AccuWeather Meteorologist Jake Sojda.
Some rain and thunderstorms can slow down the Tuesday morning commute from New York City to Philadelphia before drier weather returns in the afternoon.
The wet weather will make the rain gear a necessity and cause disruptions to outdoor activities for many in upstate New York and New England. Temperatures may fail or struggle to climb out of the 60s from Portland, Maine, to Boston and Providence, Rhode Island.
On the other hand, most of the central Appalachians and mid-Atlantic will be dry with only spotty showers and thunderstorms dotting a few communities.
Heat will surge back across the mid-Atlantic with temperatures approaching or cracking the 90-degree mark northward to around Philadelphia and Harrisburg, Pennsylvania.
Philadelphia is on track to have its first heat wave (three consecutive days of highs at or above 90) of the year as the heat holds across the mid-Atlantic through late week. Warmth and humidity will also build back across upstate New York and New England with widespread highs in the 80s from Wednesday to Friday.
Residents who have yet to put in window air conditioning units may find themselves completing that task this week. Those who work outdoors will also have to take necessary precautions to avoid heat exhaustion.
Many fields across the Northeast are still too wet after the recent onslaught of downpours. A tractor left tracks in this field near Mansfield, Pennsylvania, on Saturday, June 22, 2019. (Bill Baker)
The sticky air can continue to fuel thunderstorms across only a fraction of the Northeast during the second half of the week.
The theme of drier weather is expected to continue into early July, according to AccuWeather Lead Long-Range Meteorologist Paul Pastelok.
"The period from the final three days of the month to the start of July may even be drier than normal for most areas as high pressure can be dominant for a couple of days," he said.
Download the free AccuWeather app to receive a more detailed forecast for your community. Keep checking back for updates on AccuWeather.com and stay tuned to the AccuWeather Network on DirecTV, Frontier and Verizon Fios.
Comments that don't add to the conversation may be automatically or manually removed by Facebook or AccuWeather. Profanity, personal attacks, and spam will not be tolerated.
More Weather News
Weather News - July 16, 2019, 5:26:41 PM EDT
One of the most extraordinary achievements in United States history occurred 50 years ago. Here's what the Americans who helped produce a "giant leap for mankind" had to say about the mission.
Barry may still pack a punch with heavy thunderstorms, localized flooding
Over the weekend, people in the Northeast watched as Barry made landfall on the Gulf Coast as a hurricane. Now, the tropical rainstorm continues its slow march and will bring those people heavy rain and thunderstorms.
US heat wave to hit at a 'critical time' for crops and farmers
An AccuWeather analyst says areas that aren't expected to get rain could see things 'go downhill'
More than 70 dogs rescued from Arkansas animal shelter after Barry's rain triggers flooding
Weather News - July 16, 2019, 10:00:38 PM EDT
The tropical rainstorm continues its move inland, weakening as it pushes north, but drenching areas that lie in its path with heavy rainfall and causing flash-flooding emergencies in parts of Arkansas.
British Open 2019: Rain, gusty winds to bring daily challenges for golfers
Weather News - July 16, 2019, 10:58:36 AM EDT
The world's oldest golf championship returns to Northern Ireland for the first time in 68 years and the weather may be a factor in the outcome.
More than 100 killed in flooding, mudslides as monsoon downpours drench India, Nepal
Heavy rainfall has triggered deadly flooding and mudslides across parts of Nepal and northern India in recent days and more rain is on the way.
Stifling heat, humidity to follow Barry in southern US
AccuWeather RealFeel Temperatures are about to soar to as high as 110 degrees in some parts of the southern U.S. now that Barry has moved on out.

redpajama_set_name: RedPajamaCommonCrawl


I found a post by sargenthp in May about the same basic setup.
My problem isn't that I cannot find the menu to adjust chime and turn signal volume, I was able to find with the help of phone support.
My problem is that the chime and turn signal sounds are coming through the 2 wire speaker that came with the kit, instead of through the stereo. I checked OnStar last night (which I have never used), and it is playing through the receiver as expected.
I have done the master reset from them Maestro Audio setup in the receiver. I adjusted the chime and turn signal to a volumes to 1, as I mounted the kit speaker on the dash right behind the gear shift. It was deafening at default levels.
Unless your speaker is defective, a volume of 1 should be whisper quiet. Most people mount the speaker in the driver's side underdash, firing toward the footwell of the vehicle. I could see that if you have the speaker pointed toward you, it could definitely sound louder than if you mounted it in the underdash.
Tech support yesterday was pretty sure the chime and turn signal should be coming from the main system, not the additional speaker. That is my question. OnStar comes through primary system, chime and turn signal are coming from the GM5+ speaker.
Where those sounds come from depends on the trim of audio system you have.
In a non-amplified vehicle, chimes, turn signals and onstar come through the external speaker.
In a Bose vehicle, chimes and turn signals come from the external speaker, and Onstar is generated by the amp, which is why it comes from the vehicle speakers.
In a premium bose vehicle, the amplifier generates everything, so all of the things would come from the door speakers.
No chime sound from doors no sound from speaker no sound from signal lights as well...I'm stuck lost and confused.I did disconnect the middle speaker but I didn't think it would mute the sound. It all happened at once nothing has changed since. I have a 09 Cadillac STS with bose 15 speaker system. O and by the way everything on the radio works just no sound.
STS caddy, you might want to give us a call to troubleshoot in real time; it will be MUCH easier and faster. If you have that much stuff that isn't working, it likely won't be a simple answer that we could guess over written text.


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Former RTL Group CEO Bert Habets To Head Up Antenna Group
By Max Goldbart
Max Goldbart
International TV Editor
@Goldbart1
More Stories By Max
UK Government Freezes BBC License Fee For Two Years And Confirms Major Review Of Corporation's Funding Model
WarnerMedia Italy, Spain & Portugal Boss Barbara Salabè To Step Down After A Decade
Pitch Film Fund 2022 Unveils Winners; Big Zuu To Star In UKTV Sitcom; Hillary Clinton's HiddenLight Launches Formats Division – Global Briefs
November 2, 2021 2:30am
Bert Habets
EXCLUSIVE: Former RTL Group CEO Bert Habets has been appointed CEO of global media outfit Antenna Group. He replaces Jonathan Procter, who has returned to his native South Africa to be Group CEO of Primedia Group after a lengthy stint in charge of Antenna.
Habets, who left Fremantle owner RTL in 2019, will oversee the free TV, pay TV, OTT, content, radio, digital, music, publishing and education divisions on all platforms for Antenna, which says it currently reaches a global audience of more than 150M.
Habets replaced Anke Schäferkordt to become Co-CEO of European giant RTL Group in March 2017 alongside Guillaume de Posch, taking on the role solely later that year. He resigned in 2019 citing personal considerations and has since been a founding partner of the Dutch Museum for Electronic Museum Culture and sat on Dubai entertainment business OSN's board.
Antenna Chairman Theodore Kyriakou praised Habets' "vast operational experience and strategic mindset ."
"He will significantly contribute to our growth plans as we continue to embrace new technologies and new markets," added Kyriakou.
Habets said he had been attracted by the "ambition to grow and lead the ongoing transformation in the media industry."
Headquartered in the Netherlands and with offices in London, New York and Athens, Antenna, which launched with one TV station in Greece in 1989, now operates a wealth of free-to-air and pay-TV channels, along with its various other business units and investments in the likes of Facebook, Twitter and Spotify. Its advisory board includes former UKTV CEO Darren Childs and Aristocrat Digital CEO Mike Lang.
Last month, Sony Pictures Television sold its entire network portfolio in Central and Eastern Europe to the group, covering 22 pay-TV channels and two OTT services in 12 territories.
This article was printed from	https://deadline.com/2021/11/habets-to-head-antenna-group-1234866210/


text:
Q: PHP/MySQL If FROM Statements sorry for the extremely basic question!! I'm very new to PHP/MySQL
How would it be possible to do an if statement referencing wherever or not data was from a certain table.
Would this work?
if ( $search FROM "table2" )
{
function for table2.. etc
}

TABLE:INSTRUMENTS
COLUMNS:
 id   instrument    grade   standard    comments
      instrument2   grade2  standard2   comments2
      instrument3   grade3  standard3   comments3
      instrument4   grade4  standard4   comments4
      instrument5   grade5  standard5   comments5

TABLE: PEOPLE
COLUMNS:
id  first  last  snumber  course  email  graduate  inumber

Basically a person from the PEOPLE table is linked via ID to instruments in the INSTRUMENTS table, I have an e-mail search function that I need to send out the relative data to the relative instruments.
I want to get the comments[i] , grade[i], standard[i] of the matching instrument[i]

A: Somewhere in your code you must already have specified the table to select from. You can use the same logic to see which table you initially used?
For example:
$sTable = 'table2';
$rResult = mysql_query(sprintf($sQuery, $sTable));
if ($sTable == 'table2') { // use $rResult }

A: You know what table it came from, because you retrieved it from that table.
Update
Perhaps:
$search = trim(stripslashes($_POST['search']));
$search = mysql_real_escape_string($search);

//Find instruments searched for:

$query = "
  SELECT *,
         ('$search' IN `instrument`)  AS `matched1`,
         ('$search' IN `instrument2`) AS `matched2`,
         ('$search' IN `instrument3`) AS `matched3`,
         ('$search' IN `instrument4`) AS `matched4`,
         ('$search' IN `instrument5`) AS `matched5`
   FROM `instruments`
  WHERE '$search' IN (`instrument`, `instrument2`, `instrument3`, `instrument4`, `instrument5`)
";

Explore the results and find out how to use them to your advantage.
This isn't the most glamourous solution and you can no doubt improve this with a different approach, but it's something to get you started.

A: Hmm,
The tables need a redesign IMHO.
I would change table instruments to.
id, people_id, instrument, grade, standard, comments

This query:
SELECT
  people.email
  ,instruments.instrument
  ,instruments.grade
  ,instruments.standard
  ,instruments.comment
FROM people
INNER JOIN instruments ON (instruments.people_id = people.id)
WHERE people.id = 10

Will give you all instruments for person number 10.
You can change the where clause to where people.snumber = x or whatever you feel like.
Or add extra clauses to limit the number of instruments by adding something like : AND instrument.grade > 7 at the end
With this setup people can have any number of instruments.
It feels a bit odd to -reverse link- the instruments to people like this, but believe me... it works.
I recommend reading up on joins (google 'mysql join') and always use explicit joins using the join keyword, it makes understanding your queries much easier.
If this is the result you where looking for, then you can drop the inumber field from the people table, since we moved the link between people and instruments to the instrument table.
On an 1-to-many link the linking field should always be on the 'many'-table.

A: You would need to store what table the search result was from in a variable, and compare the two variables.
if($search === "table2")

There is no from operator in PHP.

redpajama_set_name: RedPajamaStackExchange


text:
ashoka university admission 2020 last date
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For admissions to this course, candidates need to apply online, along with the following –, Fill up the online application form, and provide –, The 2 documents above have to be emailed to physics.phd@ashoka.edu.in. in any branch of Computer Science/Mathematics/Statistics/Computer Applications / MCA equivalent, Minimum 55% marks in MA / M Phil in English. ), Mathematics and Computer Science (B.Sc Hons. Ashoka University UG Admission 2020: Applications will be invited by Ashoka University from the eligible candidates for admission to Undergraduate programmes for the academic year 2019-20.Candidates who are interested in taking admission UG Programme in this university for the upcoming session have to fill Ashoka University UG application form as per prescribed schedule. The Undergraduate Degree programme offers Pure Subject Majors in: Computer Science (B.Sc. A. Ashoka is a research university based near New Delhi, India. Ashoka University is a UGC-recognised multidisciplinary university situated in Sonepat, Haryana. ), Political Science (B.A. Calcutta University Admission 2020 PG Courses – Last Date to Apply Extended. The last date for submission of Round 1 applications is 13 November, 2019. Hons. A brief statement of research interests (max 1 page), M.Phil/Ph.D in Science - Doctorate (Science), MBA/PGDM - Masters (Business Administration), BBA/BBM - Bachelors (Business Administration), Bachelor of Animation - Bachelor (Animation), Bachelors (Animation & Graphic Design) - Bachelor (Arts), Bachelor of Physiotherapy(BPT) - Bachelor (Medical), B.Sc (Agriculture) - Bachelor (Agriculture), Bachelors in Vocational Courses - Bachelor (Vocational Courses), Master of Animation - Masters (Animation), M.Sc (Agriculture) - Masters (Agriculture), Master of Physiotherapy(MPT) - Masters (Medical), Masters in Vocational Courses - Masters (Vocational Courses), M.Phil/Ph.D in Paramedical - Doctorate (Paramedical), M.Phil/Ph.D in Medicine - Doctorate (Medical), M.Phil/Ph.D in Pharmacy - Doctorate (Pharmacy), Ph.D in Veterinary Science - Doctorate (Veterinary Sciences), M.Phil/Ph.D in Mass Communication - Doctorate (Mass Communications), M.Phil/Ph.D in Management - Doctorate (Management), M.Phil/Ph.D in Architecture - Doctorate (Architecture), M.Phil/Ph.D in Commerce - Doctorate (Commerce), M.Phil/Ph.D in Computer Applications - Doctorate (Computer Applications), M.Phil/Ph.D in Dental - Doctorate (Dental), M.Phil/Ph.D in Agriculture - Doctorate (Agriculture), M.Phil/Ph.D in Design - Doctorate (Design), M.Phil/Ph.D in Hotel Management - Doctorate (Hotel Management), M.Phil/Ph.D in Engineering - Doctorate (Engineering), M.Phil/Ph.D in Education - Doctorate (Education), A person who can be contacted for any further enquiry. Ashoka University's admission process varies for each course. The faculty of Computer Science has prepared a guideline on what to expect. Candidates who had applied for the test will be notified of the same between January 8-13, 2021. Ashoka University PG Course Admission Eligibility Criteria Ashoka University (AU): M.A, Ph.D Admission 2020 Updated On - Monday, 02 March 2020 Ashoka University (AU) offers following programs for the academic year 2020-2021 Hons.). It provides a wide platter of options. Last Merit BS 2019. Last Date to Submit Registration Fee: Single Fee 4090/-13 july 2020 to 30 October 2020: Single Fee 4090/- + 1000/- Late Fee = 5090/-31 October 2020 to 31 December 2020 : Double Fee 8180/-01 January 2020 to 26 Februray 2021: Who Can Apply for Punjab University Private Admissions 2020 for Associate Degree Programs. GJU conducts an entrance test to shortlist the aspirants for admission in the university. Hons. April-May 2021. Apply For Admission. Ashoka University UG Course Admission Eligibility Criteria. The University offers admission in various UG and PG programmes in the fields of Engineering, Economics, Management and Commerce fields. The admission forms will be available from date 01-09-2020 and the last date for submission of admission application form is 21-09-2020. Ashoka University announced the appointment of Dr. Shahid Jameel as Director of th, Follow & Share this college to get information about admission, COPYRIGHT © 2021 COLLEGEDUNIA WEB PVT. Admissions will be based on a written test and interview. ), Politics, Philosophy and Economics (B.A. Gauhati University Latest Notification on M.A/M.SC/M.COM PG Admission Schedule 2020 & Results 2020 . No need to remember deadlines as I get timely updates now. AIOU Admission 2021 – 2022 Last Date to Apply Online: Aiou admission procedure is very simple and symbolic for all degrees. 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text:
Editorial counsil
B.V. Boytsov (editor-in-chief)– doctor of technical sciences, professor, honored worker of science of RF, head of chair 104 "Technological design and quality management" of FGBOU PO "Moscow aviation institute (national research university)", first vice-president of MOO "Academy of quality problems", Moscow
N.S. Kruglov (first deputy editor-in-chief) - chief scientific secretary of MOO "Academy of quality problems", Moscow
E.A. Sidorov (deputy editor-in-chief) - candidate of economic sciences, chief executive of MOO "Academy of quality problems", Moscow
D. Kempbell – doctor, deputy director of the European center for quality, England
M.Yu. Kuprikov – doctor of technical sciences, professor, vice rector for study of FGBOU VPO "Moscow aviation institute (national research university)", Moscow
O.A. Gorlenko - doctor of technical sciences, professor, honored worker of science of RF, head of quality department of education in the University FGBOU VPO « Bryansk state technical University», vice-president of Bryansk regional office of MOO "Academy of Quality Problems", Bryansk
G.N. Ivanova – candidate of economic sciences, associate professor, head of Body for certification of systems of management LLC "Test-St.Petersburg", St. Petersburg
I.A. Sosunova – doctor of sociological sciences, professor, vice-president of the Russian Society of Sociologists, Moscow
V.P. Marin - doctor of technical sciences, professor, honored worker of science of RF, FGBOU VPO "Moscow state technical university of radio engineering, electronics and automatic equipment", Moscow
U.I. Deniskin – doctor of technical sciences, professor, vice rector for quality and informatization of FGBOU VPO "Moscow aviation institute (national research university)", Moscow
V.Ya. Kershenbaum – doctor of technical sciences, professor, honored worker of science of RF, head of the department "Standardization, certification and quality management of production of the oil and gas equipment" of FGBOU VPO "Gubkin Russian state university of oil and gaz", Moscow
E.V. Dubinskaya (responsible secretary) – candidate of technical sciences, head of department of information technologies of MOO "Academy of Quality Problems"; Moscow
G.I. Elkin (chairman) – doctor of economic sciences, general director of Joint-stock company "Awards of the Labour Red Banner research institute of the automatic equipment of the academician V. S. Semenikhin", Moscow
A.V. Abramov - head of Federal agency for technical regulation and metrology, Moscow
Yu.P. Adler – candidate of technical sciences, professor of chair of certification and analytical control FGAOU VPO "National research technological university "MISiS"", president of office "Statistical methods and monitoring of quality" of MOO "Academy of quality problems", Moscow
V.N. Azarov – doctor of technical sciences, professor, director of the European center for quality, president of office "High school" of MOO "Academy of quality problems", Moscow
V.N. Bas – doctor of economic sciences, general director of FBU "Rostest-Moscow", president of Moscow regional office of MOO "Academy of quality problems", Moscow
F.V. Bezyazichniy – doctor of technical sciences, professor, honored worker of science of RF, head of the chair "Technology of aviation engines and general mechanical engineering" of FGBOU VPO "Rybinsk state technical university of P. A. Solovyov", president of the Yaroslavl office of MOO "Academy of quality problems", Rybinsk, Yaroslavl region
V.Ya. Belobragin – doctor of economic sciences, professor, deputy chief editor of the magazine "Standards and Quality", Moscow
B.V. Boytsov (editor-in-chief) – doctor of technical sciences, professor, honored worker of science of RF, head of chair 104 "Technological design and quality management" of FGBOU PO "Moscow aviation institute (national research university)", first vice-president of MOO "Academy of quality problems", Moscow
I.N. Bokarev – doctor of medical sciences, professor of GBOU VPO "Sechenov First Moscow state medical university" of Ministries of Health of the Russian Federation, Moscow
V.A. Vasiliev – doctor of technical sciences, professor, head of chair "Instrument maker" of FGBOU VPO "Penza state university"; Penza
S.A. Vasin – doctor of technical sciences, professor, honored worker of science of RF, head of chair "Design" of Tula state university, president of Tula regional office of MOO "Academy of quality problems", Tula
V.G. Versan – doctor of economic sciences, professor, general director of JSC "VNIIS", Moscow
G.P. Voronin – doctor of economic sciences, doctor of technical sciences, professor, president of the All-Russian organization of quality, editor-in-chief of the magazine "Standards and Quality", Moscow
A.N. Geraschenko – doctor of technical sciences, professor, rector of FGBOU VPO "Moscow aviation institute (national research university)", Moscow
O.A. Gorlenko - doctor of technical sciences, professor, honored worker of science of RF, head of quality department of education in the University FGBOU VPO « Bryansk state technical University», vice-president of Bryansk regional office of MOO "Academy of Problems of Quality", Bryansk
Yu.A. Gusakov – doctor of economic sciences, professor, vice-president of All-Russian organization of quality, Moscow
S.G. Emelianov – doctor of technical sciences, professor, rector of FGBOU VPO "Southwest state university", Kursk
L.K. Isaev – doctor of technical sciences, professor, deputy director of FGUP "BNIIMS" for scientific works, Moscow
Yu.S. Karabasov – doctor of technical sciences, professor, honored worker of science of RF, president of FGAOU VPO "National research technological university "MISiS", president of office "Metallurgy" of MOO "Academy of quality problems", Moscow
I.A. Korovkin – candidate of economic sciences, executive director of NP "Merger of Car Makers of Russia"; Moscow
Yu. V. Kryanev – doctor of philosophy, professor, honored worker of science of the RF, head of the department of philosophy of FGBOU VPO "Moscow aviation institute (national research university)", president of office "Quality Philosophy" of MOO "Academy of quality problems", Moscow
V.I. Kulaikin – candidate of psychological sciences, director of NIITE MGTU MIREA, president of office "Quality problems of design and ergonomics of MOO "Academy of quality problems", Moscow
A.M. Muratshin – doctor of technical sciences, director of FBU "State regional center of standardization, metrology and tests in the Republic of Bashkortostan", Ufa, the Republic of Bashkortostan
V.V. Okrepilov – doctor of technical sciences, professor, honored worker of science of RF, academician of RAS, general director of FBU "Test-St. Petersburg", president of St. Petersburg's regional office of MOO "Academy of quality problems", St. Petersburg
G.V. Pankina – doctor of technical sciences, professor, rector of GOU DPO "Academy of standardization, metrology and certification", Moscow
M.L. Rahmanov – doctor of technical sciences, professor, deputy general director of JSC "VNIIS", Moscow
A.A. Rizhkin – doctor of technical sciences, professor, honored worker of science of RF, head of chair "Tool production" of FGBOU VPO "Don state technical university", Rostov-on-Don
Yu.A. Rizhov – doctor of technical sciences, professor, academician of RAN, head of chair 105 "Aerodinamics LA" of FGBOU VPO "Moscow aviation institute (national research university)", Moscow
A.K. Skvorchevskiy – doctor of technical sciences, professor, the head of the laboratory of ergonomic researches of a human factor of FGBUN "Institute of Engineering science of Blagonravov of the Russian academy of sciences (IES RAS), Moscow
P.B. Shelisch – candidate of philosophy, chairman of the All-Russian union of the public associations "Consumers Union of the Russian Federation", Moscow
B.A. Yakimovich – doctor of technical sciences, professor, honored worker of science of RF, rector of FGBOU VPO The Izhevsk state technical university of M. T. Kalashnikov"; Izhevsk, Udmurt Republic


text:
RR 435: Alternatives to Adding React with Graham Conzett
Episode 443 · October 22nd, 2019 · 59 mins 28 secs
Graham Conzett has been a developer for 12 years. He has worked with Ruby and Rails for half of that, and currently works for a company that does large format touchscreens. Graham gave a talk at RailsConf 2018 called "Old School JavaScript and Rails" where he talks about the experience of JavaScript fatigue. The world of JavaScript changes very quickly, and sometimes it feels like there's a new framework every week. Because there is no clear winner among these frameworks, many Rails developers feel compelled to reach for something like React. However, there are many strategies for doing JavaScript in Ruby and in Rails that existed before these frameworks, so you can accomplish what you want to get done without bringing one in. Remember that all of them can coexist side by side, so you don't have to pick one strategy. The panel discusses the effect that adopting a new technology can have on the team, such as the learning curve and hiring people that specialize in it.
To illustrate this, Graham talks about the company he works for. Their app is a 90% is a Rails app, and one component has a lot of React. He talks about how they came up with that strategy and how they have kept React isolated to that page. It's crept into some other little places, but there is a document in the team charter that defines where and why they use certain things, and that has kept it limited.
Graham talks about the tradeoffs between choosing to stay in Rails or introduce React. If you bring in React, you have to bring in a different testing framework. React also has a bigger learning curve than standard HTML or CSS. There are far less conventions around React than Rails, so you have to spend time coming to a consensus as a team. Webpacker helps with this to a degree, but it also pulls in a bunch of third party plugins, so Rails is no longer writing the rules and you may have to debug random plugins.
If you want to avoid adding a framework like React, consider using ujs, or Unobtrusive JavaScript. These are JavaScript 'helpers' included in the Rails bundle that you can add to various buttons that help you decorate and enhance. You don't have to change much of your HTML frontend code but it makes it more interactive. Graham talks about he uses them and why he likes them. The panel compares using ujs to other strategies like using Stimulus or 'sprinkles' of JavaScript. For small JS sprinkles, Graham advises to keep that focused on a single HTML element and bound to a single event handler. Ujs works best when you piggyback off of that Rails/Rest related stuff, and Stimulus is more about manipulating parts on the page that don't have a need for asynchronous request. You can really use ujs everywhere, so the three techniques are not mutually exclusive.
Graham gives advice to developers considering pulling in a frontend framework. He says to start with minimal JS and then talk to your team about when it feels right to do it, because that's a tricky conversation to know what your expectations are and problems you're trying to solve. Sometimes things will force the issue and make you want to explore using frontend frameworks. When it's a time saver, it makes your team scale better, or when you have something you just can't do without it, then that might be the right time to use React.
The show concludes with the panel discussing their experiences with different compiling languages like TypeScript. They talk about what influences the tools people choose. They agree that the most important thing is getting working code out there, it doesn't really matter how it's written, but to only pull things in when you know you need it.
David Kimura
With special guest: Graham Conzett
Old School JavaScript and Rails at RailsConf 2018
React Native Web
Rails-ujs
Turbolinks
Stimulus Reflex
Actionview components
St. George Marathon
David Kimura:
WeDo 2.0 by Lego
Workflow Automation Self Hosted
Andrew Mason:
Publish to Github action
JustDunning.com
Company of One by Paul Jarvis
IndieHackers
Graham Conzett:
Basecamp's Shape Up
Pigeonforteachers.com
IKE Smart City
Follow Graham @gconzett on Twitter and Github
Graham Conzett


●Guru "No Time To Play"
●Roger Nichols & The Small Circle Of Friends "Don't Take Your Time"
●Biz Markie "Busy Doing Nuthin'"
●The Heavy Blinkers "Didn't Have Time To Dream It"
●Brand New Heavies Feat. Gang Starr "It's Getting Hectic"
●ROUND TABLE "MEXICAN DRAG RACE"
●Elvis Costello & The Attractions "Busy Bodies"
●Beastie Boys "Now Get Busy"
●Matthew Sweet "Save Time For Me"
●Chet Baker "Little Man You've Had a Busy Day"
●The Smiths "These Things Take Time"
●Harpers Bizarre "There's No Time Like Today"
●The Durutti Column "Take Some Time Out"
●Richard X. Heyman "When It Was Our Time"
●Built To Spill "Time Trap"
●Sylvester Weaver "I'm Busy And You Can't Come In"
●Gang Of Four "Outside The Trains Don't Run On Time"
●The Hollies "Give Me Time"
●Kero One Feat. Clara C, Dumbfoundead "In Time"
●Floor "No Waste Of Time"


text:
FROM mcr.microsoft.com/dotnet/core/sdk:3.1.101 AS build
RUN apt-get update
RUN apt-get -yqq install clang zlib1g-dev libkrb5-dev libtinfo5
WORKDIR /app
COPY PlatformBenchmarks .
RUN dotnet publish -c Release -o out -r linux-x64

FROM mcr.microsoft.com/dotnet/core/runtime-deps:3.1 AS runtime
WORKDIR /app
COPY --from=build /app/out ./

ENTRYPOINT ["./PlatformBenchmarks", "--server.urls=http://+:8080", "KestrelTransport=LinuxTransport"]

redpajama_set_name: RedPajamaGithub


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text:
Dakota, CC-129/C-47/DC-3
Tail #: 12963
Dimensions: Wingspan: 28.95m, Length: 19.64m
Max Weight: 11,793kg
Max Speed: 369 km/h
Crew: 2 pilots, 3 crew, 36 passengers
Role: Transport, Trainer, Target Towing, and Search & Rescue
In service: 1943-1989
In January 1944, the aircraft was delivered to the RAF and given the serial number FZ658. While with the RAF, it served with 512 Squadron (Broadwell) and 48 Squadron (Down Ampney). On the night of June 5, 1944, FZ658 was one of 32 Dakotas from 512 Squadron to drop paratroopers of the 6th Airborne Division behind enemy lines in Normandy for Operation Tonga (part of the larger Operation Overlord and D Day landings).
In September 1945, FZ658 was tasked for use in India, with the RCAF's 435 and 436 Squadrons. Like many other Dakotas, the Museum Dak's job was to transport supplies and troops from India to the British Army in Burma during the war in the Pacific. When the war ended, it was the last Canadian aircraft to leave Burma. It returned to England with 435 Squadron and in 1946 it was officially transferred to 436 Squadron of the RCAF fleet. Because of this, the Museum's DC-3 was repainted in the "Canucks Unlimited" Burma colours. After the Second World War, it served in various squadrons in Canada until its retirement in 1989.


text:
The Aerospace Corporation
Mission Success
Resilient Space
Beyond Space
isakowitz
Back to the Moon
NASA has plans to put humans on the moon. Here's how Aerospace is helping to make that happen.
NASA wants back on the moon. While the agency has enjoyed success with the International Space Station and Mars rovers, no astronaut has set foot on the moon since Apollo 17 in 1972. Now, acting under the mandate established by Space Policy Directive 1 and signed by President Donald Trump on Dec. 11, 2017, the agency is charged with creating a human presence on the moon. NASA has embarked on several programs to achieve that goal, and The Aerospace Corporation is closely involved with several projects crucial to returning humans to the moon.
The center of NASA's lunar plan is called the Gateway, which will be a small space station that would orbit the moon and serve as a staging platform for trips to the moon's surface. Aerospace engineers are closely involved with the overall design as well as systems engineering and integration of the various modules that will comprise the Gateway.
NASA engineers and astronauts perform tests at the agency's Johnson Space Center in Houston to help engineers refine requirements for the design of a deep space habitat, one of several elements comprising the Gateway. (Photo: NASA)
Part of that integration includes designing and testing the living quarters, or habitation module, for the Gateway. Aerospace employees are part of the NASA Gateway Ground Test Team, which has been tasked with evaluating five habitation module mockups built by various contractors — Northrop Grumman, Boeing, Lockheed Martin, Sierra Nevada Corporation, and Bigelow Aerospace. A sixth firm, Nanoracks, has proposed a habitation concept. Aerospace employees are participating as ground test experts, subject matter experts, and engineering test subjects to accomplish these evaluations. Astronauts and engineers will work in each of the mockups, performing activities that simulate three days of astronaut crewmembers living and working aboard the Gateway.
"The results of those ground tests will be provided to NASA program management to help them understand what capabilities we need to build into our hab module to make it safe, comfortable, efficient, and productive for our crews," said Jason Poffenberger, engineering specialist with the Aerospace Human Exploration and Spaceflight Division at the Johnson Space Center.
During Exploration Mission-1, Orion will venture thousands of miles beyond the moon during an approximately three-week mission. (Image: NASA)
Aerospace engineers are also involved in the development of the Orion capsule, which will transport astronauts to the Gateway. On the Orion space capsule, which will be attached to NASA's Space Launch System rocket, Aerospace has taken a key role in designing and testing the avionics, which includes data handling subsystems, interfaces with other parts of the capsule, flight software, power, and wiring. Aerospace engineers work closely with Lockheed Martin on all aspects of the Orion avionics.
As NASA firms up its plans for returning to the moon and going beyond, Aerospace will be ready to assist with its expertise gained from nearly 60 years of innovative and ground-breaking science and engineering.
Testing Orion's Impenetrable Shield
The Orion spacecraft will endure temperatures of 5000 degrees when it re-enters our atmosphere. Aerospace engineers developed a new tool to make sure the spacecraft -and those inside- survive the ride...
Trusted AI and Autonomous Systems
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Role of the human supplementary eye field in the control of saccadic eye movements.
The precise function of the supplementary eye field (SEF) is poorly understood. Although electrophysiological and functional imaging studies are important for demonstrating when SEF neurones are active, lesion studies are critical to establish the functions for which the SEF is essential. Here we report a series of investigations performed on an extremely rare individual with a highly focal lesion of the medial frontal cortex. High-resolution structural imaging demonstrated that his lesion wa...
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Parton, A., Nachev, P., Hodgson, T. L., Mort, D., Thomas, D., Ordidge, R., Morgan, P. S., Jackson, S., Rees, G., & Husain, M. (2007). Role of the human supplementary eye field in the control of saccadic eye movements. Neuropsychologia, 45(5), 997–1008.
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Parton, A., et al. "Role of the Human Supplementary Eye Field in the Control of Saccadic Eye Movements." Neuropsychologia, vol. 45, no. 5, 2007, pp. 997–1008.
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Parton, A, P Nachev, TL Hodgson, D Mort, D Thomas, R Ordidge, PS Morgan, S Jackson, G Rees, and M Husain. 2007. "Role of the Human Supplementary Eye Field in the Control of Saccadic Eye Movements." Neuropsychologia 45 (5): 997–1008.
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10.1016/j.neuropsychologia.2006.09.007
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Tonight the 68th San Remo Festival in Italy finished and we have the results.
Annalisa, La Stato Social and Ermal Meta & Fabrizio Moro made it through to the Superfinal where a further vote took place.
But will Ermal Meta & Fabrizio Moro choose to go to Eurovision? Soon we will find out.


Трансмембранные рецепторы семейства Notch, представленные у человека 4 белками (Notch1–4), активируются при непосредственном физическом контакте с клетками, содержащими Notch-лиганды семейств Jagged и Dll. Такое взаимодействие приводит к серии протеолитических расщеплений рецептора, в результате чего его внутриклеточный домен транслоцируется в ядро, и происходит активация транскрипции генов, регулирующих баланс между пролиферацией, клеточной смертью и дифференцировкой. Белки семейства Notch оказывают влияние на внутриклеточные сигнальные пути и межклеточные взаимодействия большинства типов клеток. Notch не только регулирует многие этапы эмбриогенеза, но и участвует в поддержании гомеостаза тканей и органов взрослого организма.
Нарушения активации Notch приводят к различным заболеваниям, в том числе участвуют в канцерогенезе. Наиболее хорошо исследованы нарушения Notch при различных гемобластозах, однако в последние годы выявлено их участие и в инициации и прогрессии солидных опухолей человека. Способность Notch выступать в качестве онкогена или проявлять свойства опухолевого супрессора зависит не только от гистогенетического типа экспрессирующих его клеток, но и от их микроокружения.
В обзоре рассматриваются как канонический сигнальный путь Notch, так и неканонические механизмы его активации, эпигенетическая регуляция, а также современные данные об опухоль-супрессирующих и опухоль-промотирующих эффектах этих белков в злокачественных новообразованиях человека. Отдельное внимание уделено взаимодействию между Notch и другими сигнальными путями, контролирующими процессы эпителиально-мезенхимального перехода, формирования и поддержания фенотипа стволовых клеток и специфических ниш, дифференцировки и ангиогенеза как при нормальном развитии, так и в контексте канцерогенеза. Фармакологическое регулирование активации Notch может быть одним из подходов к терапии многих злокачественных новообразований человека.
1. Рыбко В.А., Копнин Б.П., Хромова Н.В. и др. Роль изменений активности белков Notch в онкогенезе: множественные механизмы и возможности прикладного использования. Клиническая онкогема- тология 2011;4(2):103–10. [Rybko V.A., Kopnin B.P., Khromova N.V. et al. Role of Notch signaling in tumorigenesis: multiple mechanisms and therapeutic potential. Klinicheskaya onkogematologiya = Clinical Oncohematology 2011;4(2):103–10. (In Russ.)].
2. Kidd S., Kelley M.R., Young M.W. et al. Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors. Mol Cell Biol 1986;6(9):3094–108.
3. Greenwald I. The lin-12 locus of Caenorhabditis elegans. Bioessays 1987;6(2):70–3.
4. Ellisen L.W., Bird J., West D.C. et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991;66(4):649–61.
5. Francis R., McGrath R., Zhang J. et al. Aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Dev Cell 2002;3(1):85–97.
6. Schroeter E.H., Kisslinger J.A., Kopan R. et al. Notch-1 signalling requires ligand- induced proteolytic release of intracellular domain. Nature 1998;393(6683):382–6.
7. Strooper B.D., Annaert W., Cupers P. et al. A presenilin-1-dependent gamma-secretase- like protease mediates release of Notch intracellular domain. Nature 1999;398(6727):518–22.
8. Louvi A., Artavanis-Tsakonas S. Notch and disease: a growing field. Semin Cell Dev Biol 2012;23(4):473–80.
9. Demehri S., Turkoz A., Kopan R. Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. Cancer Cell 2009;16(1):55–66.
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13. Bray S.J. Notch signalling: a simple pathway becomes complex. Nat Rev 2006;7(9):678–89.
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15. Alberi L., Lui S., Wang Y. et al. Activity- induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks. Neuron 2011;69(3):437–44.
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21. Weinmaster G., Fischer J.A. Notch ligand ubiquitylation: what is it good for? Dev Cell 2011;21(1):134–44.
22. Jorissen E., De Strooper B. Gamma- secretase and the intramembrane proteolysis of Notch. Curr Top Dev Biol 2010;92:201–30.
23. Borggrefe T., Liefke R. Fine-tuning of the intracellular canonical Notch signaling pathway. Cell Cycle 2012;11(2):264–76.
24. Nagel A.C., Krejci A., Tenin G. et al. Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors. Mol Cell Biol 2005;25(23):10433–41.
25. Oswald F., Winkler M., Cao Y. et al. RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes. Mol Cell Biol 2005;25(23):10379–90.
26. Wallberg A.E., Pedersen K., Lendahl U. et al. P300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. Mol Cell Biol 2002;22(22):7812–9.
27. Hubbard E.J., Wu G., Kitajewski J. et al. Sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev 1997;11(23):3182–93.
28. Fryer C.J., White J.B., Jones K.A. Mastermind recruits CycC: CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol Cell 2004;16(4):509–20.
29. Capaccione K.M., Pine S.R. The Notch signaling pathway as a mediator of tumor survival. Carcinogenesis 2013;34(7):1420–30.
30. Greenwald I. LIN-12/Notch signaling: lessons from worms and flies. Genes Dev 1998;12(12):1751–62.
31. Ohlstein B., Spradling A. Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling. Science 2007;315(5814):988–92.
32. Bicker F., Schmidt M.H. EGFL7: a new player in homeostasis of the nervous system. Cell Cycle 2010;9(7):1263–9.
33. Pompa J.L., Wakeham A., Correia K.M. et al. Conservation of the Notch signalling pathway in mammalian neurogenesis. Development 1997;124(6):1139–48.
34. Mani S.A., Guo W., Liao M.J. et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008;133(4):704–15.
35. Quaegebeur A., Lange C., Carmeliet P. The neurovascular link in health and disease: molecular mechanisms and therapeutic implications. Neuron 2011;71(3):406–24.
36. Perdigoto C.N., Bardin A.J. Sending the right signal: Notch and stem cells. Biochim Biophys Acta 2013;1830(2):2307–22.
37. Carlson M.E., Hsu M., Conboy I.M. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature 2008;454(7203):528–32.
38. Ohlstein B., Spradling A. The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature 2006;439(7075):470–4.
39. Bigas A., Robert-Moreno A., Espinosa L. The Notch pathway in the developing hematopoietic system. Int J Dev Biol 2010;54(6):1175–88.
40. Fernández-Sánchez V., Pelayo R., Flores-Guzmán P. et al. In vitro effects of stromal cells expressing different levels of Jagged-1 and Delta-1 on the growth of primitive and intermediate CD34(+) cell subsets from human cord blood. Blood Cells Mol Dis 2011;47(4):205–13.
41. Pooter R.F., Schmitt T.M., Pompa J.L. et al. Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors. J Immunol 2006;176(9):5267–75.
42. Varnum-Finney B., Brashem-Stein C., Bernstein I.D. Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability. Blood 2003;101(5):1784–9.
43. Ohishi K., Katayama N., Shiku H. et al. Notch signalling in hematopoiesis. Semin Cell Dev Biol 2003;14(2):143–50.
44. Weng A.P., Ferrando A.A., Lee W. et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004;306(5694):269–71.
45. Thompson B.J., Buonamici S., Sulis M.L. et al. The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia. J Exp Med 2007;204(8):1825–35.
46. Chiang M.Y., Xu L., Shestova O. et al. Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia. J Clin Invest 2008;118(9):3181–94.
47. Fabbri G., Rasi S., Rossi D. et al. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med 2011;208(7):1389–401.
48. Ranganathan P., Weaver K.L., Capobianco A.J. Notch signalling in solid tumours: a little bit of everything but not all the time. Nat Rev Cancer 2011;11(5):338–51.
49. Wang Z., Li Y., Banerjee S., Sarkar F.H. Emerging role of Notch in stem cells and cancer. Cancer Lett 2009;279(1):8–12.
50. Lu J., Ye X., Fan F. et al. Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1. Cancer Cell 2013;23(2):171–85.
51. Reedijk M., Odorcic S., Chang L. et al. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 2005;65(18):8530–7.
52. Nguyen B., Lefort K., Mandinova A. et al. Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev 2006;20(8):1028–42.
53. Rangarajan A., Talora C., Okuyama R. et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 2001;20(13):3427–36.
54. Nicolas M., Wolfer A., Raj K. et al. Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 2003;33(3):416–21.
55. Viatour P., Ehmer U., Saddic L.A. et al. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. J Exp Med 2011;208(10):1963–76.
56. Klinakis A., Lobry C., Abdel-Wahab O. et al. A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia. Nature 2011;473(7346):230–3.
57. Agrawal N., Frederick M.J., Pickering C.R. et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011;333(6046):1154–7.
58. Lobry C., Oh P., Aifantis I. Oncogenic and tumor suppressor functions of Notch in cancer: it,s NOTCH what you think. J Exp Med 2011;208(10):1931–5.
59. Wang Z., Li Y., Kong D. et al. Cross-talk between miRNA and Notch signaling pathways in tumor development and progression. Cancer Lett 2010; 292(2):141–8.
60. Leong K.G., Niessen K., Kulic I. et al. Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med 2007;204(12):2935–48.
61. Wang Z., Li Y., Kong D. et al. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res 2009;69(6):2400–7.
62. Sahlgren C., Gustafsson M.V., Jin S. et al. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci USA 2008;105(17):6392–7.
63. Jakowlew S.B. Transforming growth factor-beta in cancer and metastasis. Cancer Metastasis Rev 2006;25(3):435–57.
64. Serini G., Gabbiani G. Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res 1999;250(2): 273–83.
65. Studebaker A.W., Storci G., Werbeck J.L. et al. Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner. Cancer Res 2008;68(21):9087–95.
66. Minter L.M., Osborne B.A. Canonical and non-canonical Notch signaling in CD4+ T cells. Curr Top Microbiol Immunol 2012;360:99–114.
67. Gentle M.E., Rose A., Bugeon L. et al. Noncanonical Notch signaling modulates cytokine responses of dendritic cells to inflammatory stimuli. J Immunol 2012;189(3):1274–84.
68. Vacca A., Felli M.P., Palermo R. et al. Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. EMBO J 2006;25(5):1000–8.
69. Jin S., Mutvei A.P., Chivukula I.V. et al. Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/ IKKβ. Oncogene 2013;32(41):4892–902.
70. Ayaz F., Osborne B.A. Non-canonical notch signaling in cancer and immunity. Front Oncol 2014;4:345.
71. Garzia L., Andolfo I., Cusanelli E. et al. MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. PloS One 2009; 4(3):4998.
72. Wu Z., Wu Y., Tian Y. et al. Differential effects of miR-34c-3p and miR-34c-5p on the proliferation, apoptosis and invasion of glioma cells. Oncol Lett 2013;6(5):1447–52.
73. Wang Z., Banerjee S., Ahmad A. et al. Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways. PloS One 2011;6(6):20537.
74. Ji Q., Hao X., Zhang M. et al. MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PloS One 2009;4(8):6816.
75. Pang R.T., Leung C.O., Ye T.M. et al. MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells. Carcinogenesis 2010;31(6):1037–44.
76. Bu P., Chen K.Y., Chen J.H. et al. A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells. Cell Stem Cell 2013; 12(5):602–15.
77. Ohashi S., Natsuizaka M., Naganuma S. et al. A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors. Cancer Res 2011;71(21):6836–47.
78. Brabletz S., Bajdak K., Meidhof S. et al. The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J 2011;30(4):770–82.
79. Wang X., Lu H., Li T. et al. Krüppel-like factor 8 promotes tumorigenic mammary stem cell induction by targeting miR-146a. Am J Cancer Res 2013;3(4):356–73.


text:
require 'rss'

module AirPlayer
  class Playlist < Array
    def initialize(options = {})
      @shuffle = options['shuffle'] || false
      @repeat  = options['repeat'] || false
    end

    def add(item)
      case type(item)
      when :local_dir
        concat(media_in_local(item))
      when :podcast
        concat(media_in_podcast(item))
      when :url
        push(Media.new(item))
      end

      self
    end

    def entries(&blk)
      loop do
        shuffle! if @shuffle
        send(:each, &blk)
        break unless @repeat
      end
    end

    private

    def type(item)
      if Dir.exist?(File.expand_path(item))
        :local_dir
      elsif Media.playable?(item)
        :url
      elsif item.match(/.+(xml|rss)$/)
        :podcast
      end
    end

    def media_in_local(path)
      Dir.entries(File.expand_path(path)).sort.map do |node|
        Media.new(File.expand_path(node, path)) if Media.playable? node
      end.compact
    end

    def media_in_podcast(path)
      RSS::Parser.parse(path).items.map do |node|
        Media.new(node.link)
      end
    end
  end
end


text:
Eliáš Antonín Dohnal OSBMr, właściwie Antonín Dohnal (ur. 1946) – były czeski duchowny greckokatolicki, bazylianin, tradycjonalista katolicki, patriarcha Bizantyjskiego Katolickiego Patriarchatu na Ukrainie.

Główny lider ruchu tradycjonalistów greckokatolickich zwanego ojcami podhoreckimi, którego centrum znajduje się w klasztorze bazyliańskim Zwiastowania Najświętszej Maryi Panny w Podhorcach na Ukrainie.

Życiorys
Absolwent seminarium duchownego w Litomierzycach. W latach 1972–1991 duchowny rzymskokatolickiej archidiecezji ołomunieckiej. Za swoją aktywną działalność duszpasterską prześladowany przez StB. W 1991 r. przyjechał do Polski i wstąpił do nowicjatu Zakonu Bazylianów św. Jozafata w Warszawie.

Od 1992 r. organizował greckokatolickie życie klasztorne na Słowacji. Był założycielem klasztoru w Trebišovie. Jednocześnie pracował jako wykładowca na Wydziale Teologicznym w Preszowie. W 1997 r. otrzymał zezwolenie na utworzenie bazyliańskiej wspólnoty kontemplacyjnej Comunita monasticae vitae. Zgoda na działalność tej grupy została jednak cofnięta w następnym roku. W 1999 roku obronił doktorat z teologii na Uniwersytecie Karola w Pradze.

Na początku XXI wieku stał się głosicielem poglądów o potrzebie zachowania w Kościele greckokatolickim dotychczasowych zwyczajów i o możliwie szybkie zjednoczenie Kościołów unickich w Czechach i na Słowacji z Ukraińskim Kościołem Greckokatolickim, aby uniknęły one działania prądów reformatorskich podobnych do tych jakie miały miejsce w Kościele rzymskokatolickim. Za swoje działania oraz poglądy został obłożony karami kościelnymi.

W 2003 r. stał się jednym z głównych krytyków wyboru na greckokatolickiego egzarchę Czech, Ladislava Hučki. Oskarżył biskupa o współpracę z aparatem bezpieczeństwa Czechosłowackiej Republiki Socjalistycznej oraz o jego możliwe próby reformowania Kościoła greckokatolickiego w Czechach pod dyktando liderów wspólnoty Focolari.

Po wydarzeniach w Czechach nie mogąc się pogodzić z nowym egzarchą wraz z grupą mnichów bazyliańskich wyjechał na Słowację. Następnie na Ukrainę, gdzie osiadł w bazyliańskim klasztorze w Podhorcach. Stanął tam na czele ruchu ojców podhoreckich, który sprzeciwia się wszelkim reformom w Kościołach greckokatolickich.

Wraz z pozostałymi eparchami z ruchu ojców podhoreckich założył Prawowierny Kościół Greckokatolicki i obłożył wraz z nimi imiennie klątwami kościelnymi wszystkich biskupów katolickich na świecie. 5 kwietnia 2011 roku został wybrany przez synod biskupów Prawowiernego Kościoła Greckokatolickiego na urząd patriarchy Bizantyjskiego Katolickiego Patriarchatu na Ukrainie.

Linki zewnętrzne
 Four Words from Ukraine

Biskupi tradycjonalistyczni
Urodzeni w 1946

redpajama_set_name: RedPajamaWikipedia


text:
Robert B. Redman Stadium is an American football stadium on the campus of Bloomsburg University in Bloomsburg, Pennsylvania.  The stadium is used by the Bloomsburg Huskies football and track and field teams.

Construction on Redman Stadium began in 1972 on what is now known as the upper campus. The upper campus is home to all athletic fields and facilities for the Huskies' intercollegiate athletics teams, which compete in NCAA Division II (with the exception of wrestling, which competes in NCAA Division I). Student housing was later added to the upper campus as well.

The stadium was completed in time for the 1974 football season at a cost of $725,000. It was officially opened and dedicated on September 21, 1974. The Stadium is named after former head coach Robert B. Redman, who led the team from 1947 until 1951. He compiled a record of 38 wins, 4 losses and won three PSAC championships during his time as head coach.

Redman Stadium's first major renovation took place in the spring of 2008. The project included a new two level press box with elevator, new restroom facilities, new visitor seating, new parking lot, new ADA-compliant hand rails, track & field facilities, permanent lighting and a new artificial playing surface. The project was completed in time for the 2008 season at a cost of $3.45 million.

Seating capacity at Redman Stadium was 5,000 when originally constructed and is now officially listed at 4,775. Over the years, many crowds have exceeded capacity. The attendance record was set in 1985 when a crowd of 7,483 turned out for the Huskies' homecoming game against Millersville University.

References

External links
 Bloomsburg University athletic facilities

College football venues
Bloomsburg Huskies football
American football venues in Pennsylvania
Buildings and structures in Columbia County, Pennsylvania
Sports venues completed in 1974
1974 establishments in Pennsylvania


This is a game to use with your whole class. There are five different pages, so you could choose to use a different themed page each day, or use the same page over and over. Pick a specific behavior for the day that you want your class to work on. Drag a yes into the bin every time they do the behavior. Drag a no, every time they don't. At the end of the day pull out a token from the bin. If it's a yes, they earn a reward! Enjoy!
Your students will be sure to have fun solving these Christmas themed story problems. This flipchart features many different types of problems that include addition, subtraction, multiplication, and even division operations. Pick and choose which pages to use. The flipchart is interactive. The students can click to see which operation to use, and check the answer after it has been solved. Story problem clues are also included. Enjoy!
What a fun way for your students to learn about the Thanksgiving holiday! This Jeopardy game includes 25 categories, with each category having five questions each. The categories are: Pilgrims, Fun Facts, Math, Grammar, and Turkey! A scoreboard for four teams is included on the main page, as well as all buttons and questions needed to play the game. Page notes are also included. Adorable clip art was purchased from Krista Wallden!
Do your students get confused between their, they're, and there? Teach them the difference between these homophones with this fun, interactive, and engaging flipchart lesson. This lesson includes magic revealers, containers, plus voting for formative, or summative assessment. Links to fun homophone games, as well as a practice worksheet are also included. Enjoy!
You and your students will have fun finding out whoooooo's here each morning! When your students arrive, have them drag the owl with their student number to the "Look Whooooo's Here Today" section of the flipchart. Those owls that are left in the lower portion represent the students who are absent. Graphics purchased and licensed through Pixel Paper Prints. Enjoy!
Your students will LOVE Patty Dod's newest flipchart about number sense and subitizing. This flipchart is interactive, colorful, and incorporates many games and activities that your students won't be able to get enough of! The concept of subitizing (visually recognizing the 'amount' of dots or images without counting) is incorporated throughout her flipchart, along with a number sense concentration style game for your students to play. Enjoy!
Your students will be sure to have fun sounding out words with this newest flipchart lesson by Patty Dod. Containers, restrictors, voting, and a bunch of links to online games make this lesson highly interactive. Students get to listen to short vowel sounds and make words, along with identify the difference between a real word and a made up word. This flipchart is best suited for Pre-K, K, and 1. Enjoy!
This flipchart is a great way to call on your students. Pull their names from out of the treasure chest to come to the board, or complete tasks in your classroom. You could also use it as an attendance taker and leave their names out of the chest. When a student comes in, they drag their name into the chest. You can then easily take attendance. It is also a way for you to group your students randomly. Graphics licensed by Jessica Weible. Enjoy!
This interactive consonant blends flipchart is 70 pages and covers the consonant blends: cr, gl, pl, cr, bl, dr, sc, sn, fl, st, tr, cl, fr, sw, qu, pr, sp, sm, tw sh, gr, sl, sk, and br. This flipchart also includes a pdf file of a consonant blends book for you to print and have your students use during the lesson. Containers and interactive flipchart pages are included along with voting to use as formative or summative assessment. Enjoy!
Your students will be sure to know their numbers to 120 with this 100's Chart Activities Flipchart Lesson from Patty Dod! This lesson features tons of interaction with the board. Students get to play hundred's chart games, guess mystery numbers, solve puzzles, and vote for formative or summative assessment. Page notes are included to guide you through the lesson. This flipchart is over 30 pages! Enjoy!