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President Mohamed Waheed Endorses The WHOLE WORLD Water Campaign
WHOLE WORLD Water
- Maldives Aims to Become the First Country to Eliminate Plastic Bottled Water
NEW YORK, March 22, 2013 /PRNewswire/ -- WHOLE WORLD Water announced today that Dr. Mohamed Waheed, President of the Republic of the Maldives, will celebrate World Water Day by signing the WHOLE WORLD Water Referendum for Clean and Safe Water. The Referendum encourages the hospitality and tourism industry to replace branded bottled water with filtered water sold in recycled, reusable glass bottles, and to donate 10 percent of the proceeds to the WHOLE WORLD Water Fund. The Referendum will be signed during an on-air Google+ Hangout, today, March 22, at 11am GMT.
The WHOLE WORLD Water Google+ Hangout will highlight how governments can work with the private sector to drive positive, sustainable change. Participants in the Hangout will include President Waheed; Sir Richard Branson, founder of the Virgin Group and Virgin Unite; Sonu Shivdasani, Chairman of Soneva Resorts & Spas and co-Founder and Trustee of WHOLE WORLD Water; Dinda Elliott, Global Affairs Editor at Conde Nast Traveler; Mike Bettes, Meteorologist at the Weather Channel; Michael d'Estries, co-founder of Ecorazzi.com; Jenifer Willig and Karena Albers, co-founders of WHOLE WORLD Water.
Considered a top tourism destination by many, the Maldives is among the most vulnerable of the small island states to the consequences of climate change, and faces acute development challenges such as a shortage of potable water. With 28 percent of the GDP coming from tourism, this industry has a significant role to play in helping to mitigate these challenges.
"What our world urgently needs to achieve sustained development will require significant changes in what we produce, and how we consume our resources," said President Waheed. "It is my hope that by endorsing this initiative, all hotels and resorts in the Maldives will join WHOLE WORLD Water and that the Maldives will serve as a global example of how governments can work with the private sector to drive positive, sustainable change for all."
"We are honored to have our campaign endorsed by President Waheed," said Karena Albers, co-founder of WHOLE WORLD Water. "This is an extraordinary story of a small island state taking an astounding leadership position – setting a global example of how governments and the private sector can work together. It is important to note that funds raised by local resorts will be invested back into clean water initiatives here in the Maldives."
"Solving our world's great challenges requires screwing business as usual," said Sir Richard Branson, Founder at Virgin Group and advisor to WHOLE WORLD Water. "Through the cooperation of government and the private and social sectors through projects such as WHOLE WORLD Water, we can develop lasting business and humanitarian solutions."
Industry members and travelers everywhere are invited to tune into the WHOLE WORLD Water Google+ Hangout, today, March 22, at 11:00am GMT. For more information about WHOLE WORLD Water, please visit www.wholeworldwater.co.
About WHOLE WORLD Water:
Developed to end the global water and sanitation crisis, WHOLE WORLD Water works to engage the hospitality and tourism industry to filter, bottle, and sell its own water, and contribute 10% of the proceeds to the WHOLE WORLD Water Fund. Founded in 2012 by award winning documentary filmmaker Karena Albers, and Jenifer Willig, former CEO of the (RED) campaign, the core belief of WHOLE WORLD Water is that if it is not good for business, it is simply not sustainable. For more information, please visit www.wholeworldwater.co, and join the conversation on Twitter @WHOLEWORLDWater.
WHOLE WORLD Water Members:
To date, current members include: Soneva, Six Senses Resorts & Spas, Virgin Limited Edition, Virgin Hotels, Banyan Tree, Auberge du Soleil, TAO Restaurant Group, The Ritz-Carlton Charlotte, The Ritz-Carlton Lake Tahoe, The Ritz-Carlton San Francisco, Oberoi Hotels and Resorts, Dusit Hotels and Resorts, JetWing Hotels, The Ranch at Live Oak Malibu, Yoo Hotels, and Tsogo Sun.
SOURCE WHOLE WORLD Water


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redpajama_set_name: RedPajamaCommonCrawl


The hereditary sensory and autonomic neuropathies (HSAN), which are also referred to as hereditary sensory neuropathies (HSN) in the absence of significant autonomic features, are a genetically and clinically heterogeneous group of disorders associated with sensory dysfunction. These disorders are genetically heterogeneous and may be inherited in an autosomal dominant or recessive fashion.
Hereditary sensory and autonomic neuropathy type 1A (HSAN1A) is an axonal form of hereditary motor and sensory neuropathy charcaterized by prominent early sensory loss and later positive sensory phenomena, including dysesthesia and characteristic "lightning" or "shooting" pains. Loss of sensation can lead to painless injuries, which, if unrecognized, result in slow wound healing and subsequent osteomyelitis requiring distal amputations. This form of HSAN is often associated with progressive sensorineural deafness. Motor involvement may be severe and is usually present in advanced stages of the disease. Muscle wasting and weakness first involves distal extremities, but then progresses to proximal involment, so that wheelchair may be necessary in the sixth or seventh decade. Occasional findings may be consistent with drenching sweating of the hands and feet and pupillary abnormalities. Visceral involvement is rare. Disease onset is reportedly between the second and the fourth decade, although particularly severe cases with congenital onset have also been described. HSAN1A is autosomal dominant and is casued by mutations in the SPTLC1 gene. The pheontype may resemble the one of Charcot-Marie-Tooth disease type 2 (CMT2) with prominent sensory loss with foot ulcers and shooting pains (and, in fact, CMT2 is part of differential diagnosis of HSAN1A).
HSAN1B is also known as HSN1 with cough and gastroesophageal reflux (GER). Unexplained chronic cough, which could progress to cough syncope, may be the first symptom. Sensory loss begins in the feet and legs between the third and fifth decades. No gene is known yet for HSAN1B.
HSAN1C is caused by heterozygous mutation in the SPTLC2 gene and is inherited in an autosomal dominant manner. The neuropathy is phenotypically similar to HSAN1A but usually without autonomic signs (although autonomic dysfunction such as anhidrosis has been reported in one case). Nerve conduction velocity studies indicates a mixed axonal and demyelinating sensorimotor neuropathy. Onset may be from 5 to 50 years. Presenting symptoms imay include loss of touch and vibration in the feet, dysesthesia and severe panmodal sensory loss in the upper and lower limbs, and distal lower limb sensory loss with ulceration and osteomyelitis necessitating amputation of the right great toe. Some patients may also show distal muscle weakness. Reported additional features include scoliosis, focal epilepsy, hyperreflexia of the upper limbs, and clenched hands.
HSN1D is caused by heterozygous mutation in the ATL1 gene and is transmitted in an autosomal dominant manner. HSAN1D is characterized by adult onset of a distal axonal sensory neuropathy affecting all modalities, often associated with distal ulceration and amputation as well as hyporeflexia, although some patients may show features suggesting upper neuron involvement.
HSN1E is an autosomal dominant neurodegenerative disorder characterized by adult onset of progressive peripheral sensory loss associated with progressive hearing impairment and early-onset dementia. HSN1E is casued by heterozygous mutations in the DNMT1 gene.
HSN1F is an autosomal dominant sensory neuropathy affecting the lower limbs. Distal sensory impairment becomes apparent during the second or third decade of life, resulting in painless ulceration of the feet with poor healing, which can progress to osteomyelitis, bone destruction, and amputation. There is no autonomic involvement, spasticity, or cognitive impairment. HSN1F is caused by heterozygous mutation in the ATL3 gene (autosomal dominant inheritance).
HSAN2 is distinguished by progressively reduced sensation to pain, temperature, and touch. Onset can be at birth and is often before puberty. The sensory deficit predominantly affects lower limbs. Unnoticed injuries and neuropathic skin promote ulcerations and infections that result in spontaneous amputation of digits or the need for surgical amputation. Osteomyelitis is common and painless fractures may be a complication. Autonomic dysfunction may include hyperhidrosis, tonic pupils, and urinary incontinence in advanced stages of the disease. HSAN2A is caused by mutation in the WNK1 gene, HSAN2B is caused by mutation in the RETREG1 gene (formerly known as FAM134B or JK1), HSAN2C is caused by KIF1A mutation, and HSAN2D is caused by SCN9A mutation.
HSAN3, also known as familial dysautonomia, is caused by homozygous or compound heterozygous mutation in the ELP1 gene (formerly known as IKBKAP gene) and is inherited in an autosomal recessive fashion. Autonomic disturbances are very prominent in HSAN3. Clinical features may include defective lacrimation, episodic hypertension, hyperhidrosis, cyclic vomiting, skin blotching, absence of lingual fungiform papillae with impaired taste, vasomotor instability, glomerulosclerosis, hypoactive or absent deep tendon reflexes, relative indifference to pain and temperature, incoordination, and emotional instability. Somatic growth is poor, and by 10 years of age, 85% of patients have scoliosis. Seizures with decerebrate posturing can follow breath-holding episodes.
HSAN4, also known as congenital insensitivity to pain with anhidrosis (CIPA), is caused by homozygous or compound heterozygous mutation in the NTRK1 gene (autosomal recessive inhertiance). The onset is in early infancy with episodic fevers, extreme hyperpyrexia and recurrent febrile convulsions (due to anhidrosis) as well as self-mutilation. The cardinal feature of HSAN4 is absence of or markedly decreased sweating. Pain and temperature perception are absent. Sensory insensitivity leads to self-mutilation, auto-amputation, and corneal scarring. Hypotonia and delayed developmental milestones are frequent in the early years, but normalize with age. Scoliosis may be present (20%).
HSAN5 is caused by homozygous mutation in the NGF gene (autosomal recessive inheritance). Only a small number of cases have been described in the literature. HSAN5 is characterized by loss of pain perception and impaired temperature sensitivity, in the absence of any other major neurological anomalies. Additional features include ulcers, self-mutilation and damaged joints.
HSAN6 is thought to be cause by mutations in the DST gene with autosomal recessive inheritance. However, just one family has been reported, so additional evidence should be warranted to confirm the disease-gene association. HSAN6 is a severe autosomal recessive disorder distinguished by neonatal hypotonia, respiratory and feeding difficulties, lack of psychomotor development, and autonomic abnormalities including labile cardiovascular function, lack of corneal reflexes leading to corneal scarring, areflexia, and absent axonal flare response after intradermal histamine injection.
HSAN7 is caused by heterozygous mutation in the SCN11A gene (autosomal dominant inheritance). The clinical history may be variably characterized by congenital inability to experience pain since birth resulting in self-mutilations, slow-healing wounds, multiple painless fractures, failure to thrive secondary to intestinal dysmotility, ongoing abdominal and urinary discomfort with chronic constipation. Mild muscle weakness and delayed motor development is also seen. The autonomic involvement is suggested by hyperhidrosis and gastrointestinal dysfunction necessitating temporary parenteral nutrition.
HSAN8 is caused by homozygous mutation in the PRDM12 gene (autosomal recessive inheritance) and is characterized by congenital insensitivity to pain resulting in ulceration to the fingers, tongue, lips, and other distal appendages. Affected individuals may also have decreased sweating and tear production.
HSAN and HSN are genetically quite heterogenous. Both autosomal dominant and recessive inheritance have been reported. So far, pathogenic mutations have been reported in the following genes: ATL1, ATL3, DNMT1, DST, ELP1, KIF1A, NGF, NTRK1, PRDM12, RETREG1, SCN11A, SCN9A, SPTLC1, SPTLC2, WNK1.
Because of its genetic heterogeneity, it is recommended to test for HSAN and HSN by means of a next generation sequencing panel of genes. Breda Genetics offer HSAN and HSN genes in panels based on either Mendeliome, exome or full genome sequencing. As both point mutations and large deletions/duplications have been reported, both standard sequence analysis and copy number variation (CNV) analysis are recommended. Both studies are possible when doing next generation sequencing, thanks to the use of two differnt bioinformatics algorithms. The confirmation of one large deletion or duplication might require a second method in some cases (e.g. MLPA or qPCR). If the panel is negative, one may proceed to an add-on panel to test the genes included in the differential diagnosis or to the upgrade of the analysis of all data from exome or genome sequencing.
Posted in Academia, Disease cards, Last Update, Medical Genetics and tagged ATL1, ATL3, congenital insensitivity to pain, DNMT1, DST, ELP1, hereditary sensory and autonomic neuropathy, HSAN, HSN, KIF1A, NGF, NTRK1, PRDM12, RETREG1, SCN11A, SCN9A, SPTLC1, SPTLC2, WNK1.


Being involved in the breakdown of a relationship can be a time of intense anxiety. You may be experiencing a range of emotions – anger, resentment, fear and helplessness. It is important that you have sound, sympathetic and constructive advice about the options available to you and the possible consequences of any decision that you may be considering.
We have a very experienced team of family lawyers, including members of Resolution (formerly Solicitors' Family Law Association) and the Family Law Panel.
Our aim is to help you find the best solution based on clear and practical legal advice. We will discuss with you whether mediation may be appropriate in your particular circumstances, as an alternative to negotiation between Solicitors and Court proceedings. We will always aim to resolve any disputes by adopting a constructive and conciliatory approach but we can be tough negotiators when required!


Mobile Phone Ringing Tone Philharmonic Concert in front of the State Opera House - Vienna, Austria.
WHEN: SAT December 9th, 2006. 19:00hs sharp!
WHERE: In front of the Wiener Staatsoper.
DURATION: At least 5 minutes!
REPERTOIRE: Any MOZART ringing tones you like!
HOW: Show up there at 19:00hs and have someone you know call you at that exact time. Let your phone ring with the Mozart tone for as long as you can. Since you will obviously not pick up the phone have your friends family re-dial your number at least 3x times so we can get a nice couple of minutes of Mozart ringing tones in the air!
When done simply go in any direction you like!
Hint: Dont forget to have your mobile phone with you and make sure that your battery is fully charged. Preset your favorite Mozart ringing tone and set the phone to LOUD so even God will hear it!
Note: If you do not have a Mozart ringing tone, then fake it with Bach, Beethoven, Haydn, or any other composer of your liking. We wont tell the difference that is for sure!


Good morning! There's something special about the quiet interior of a home as the sun rises. I love the peacefulness of these paintings by painter & photographer Maria Stabio, which capture that mood perfectly.


Overcoming a phobia such as Tetanophobia- fear of lockjaw, tetanus is something I never thought about before.
Phobia Release worked for me. I have overcome my fear about lockjaw and now I am not so fussy when it comes to cuts and things like that.
This book was great. I did not believe that it would help me, but to my surprise, it did help me.
I would recommend this book to anyone that needs help overcoming his or her fear.
Thank you for making this book so available. I can appreciate good advice coming from someone that knows what they are talking about.


KickMyGraphics enables you to create and edit animated GIF images based on various media files, including .gif, .jpg, .png, .bmp, .avi, .wmv, mp4 and other formats.
The application features a frame strip allowing you to view and select the frames you want to use for your animation, a built-in player to preview the result and lots of useful editing options.
You can cut unwanted frames or skip some, select all frames and crop them simultaneously, resize and rotate the animation, set delays and repeat times, adjust quality and change the transparent background color.
Moreover, the application allows you to extract multiple video frames and save them as individual .gif images. The animation can also be opened in your default browser.
Anyone can use this software to create and edit animated GIFs from various input files.


Garlic currently is recognized as a treatments in Germany and Switzerland, where its made use of to deal with high-cholesterol amount and hypertension. Manage broadly and give a boil.
Introduction to English Language of Chinese Drug. The anti-oxidant homes help reduce steadily the odds of DNA problems. The natural sulfur substances of Bulbus Allii Cepae, such as the thiosulfinates, thiosulfonates, cepaenes, S-oxides, S,S'-dioxides, monosulfides, disulfides, trisulfides, and zwiebelanes happen just as destruction items from the obviously taking place cysteine sulfoxides (for example.
Comminuted roots, bark, and dried leaves can all seem quite similar, so that as the variety of elements of a place may have various healing virtues, it is essential to see which will be which. |Healing Herbs makes use of information. Thyme try a fragrant plant which makes an excellent extension your preparing, to some extent since it is abundant with anti-oxidants.
Posses anybody turn the transaction regarding the sunglasses and keep hidden labels. The entire herbal of arum is actually poisonous.Only the basis, dry and/or adequately prepared, needs to be put.
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Toplak Galle K.Domestic therapeutic herbs. Nyc: details on document; 2009. Modern-day natural medicinesociety wellness company (whom) estimates that 80 percentage regarding the populace of some Asian and African region currently need natural drug for most element of main medical care. Pharmaceuticals become prohibitively pricey for the majority of around the world's populace, 50 % of who stayed on significantly less than $2 U.S.
Purpose:���Root and leaf are full of mucilage, a compound that applications the liner from the lips and neck, along with the cells that lines the intestinal region. ^"Natural Herbs – Ashoka". Tamilnadu.com. People show which herbs they can not waiting to grow appear spring. Image from Shutterstock. Around 100 various vegetation had been cited, which were made use of till existing times such as for instance sage, water onion, eye, mint, usual centaury, poppy, marsh-mallow, etc.
Trouble in swallowing, hoarseness, labored breathing, weakness, confusion, severe swelling, and sensation of panic.A worse response leads to the closure of the airway or shock (cyanosis as well as a fall in blood-pressure), creating unconsciousness. Preventing the stings or bites is much preferable than the usual cure.
Use tweezers to remove the stinger from your skin. Reactions can happen within within seconds or hours. If treatment isn't sought promptly, death can result. If there is a known allergy to some specific venom, have a physician prescribe a crisis treatment kit. For ant, mosquito, and chigger bites, clean the region thoroughly with soap and water. Apply a paste made from baking soda and water. Forchigger stings, make use of a brush and scrub. Use ice-packs if swelling occurs. For tick bites, don't use home remedies like kerosene, turpentine, or petrolatum. Remove the tick when possible with tweezers, set near your skin and attempting not to abandon the the top or some portion of the tick in the skin. The more rapid the tick is eliminated, thechances of getting Lyme disease are less.Do not touch the tick with yourhands. This minimizes the itching as well as the swelling. Another treatment for bee or wasp stings:the ivy vine-growing on the backyard wall or a tree.
Eastland push, 3rd release, p. medical identity: Taraxacum officinaleCommon brands: Lion���s enamel, blowball, fairy time clock, wetweed, priests CrownFamily: AsteraceaePart utilized: foliage, flora, rootHabitat: Dandelion is actually indigenous to European countries and Asia but expand all over the globe medical identity: Angelica sinensisCommon labels: Dang gui, tang-kuei, danggui, Chinese angelicaFamily: ApiaceaePart applied: RootHabitat: This natural herb try indigenous to Asia, Japan, and Korea Pharmazie, 1987, 42:687���688. Additional typical utilizes with this place happened to be to take care of bust irritation, digestive tract disorders, appendicitis also to promote dairy circulation.
Herbal treatments are noticed by some[who?] as cure to get wanted to pure health substances which were industrially made. In Asia the natural remedies can be so prominent that the federal government of Asia has established a different department AYUSH under the Ministry of Health & families benefit. Diet for renal rock protection, nationwide renal and Urologic DiseasesInformation Clearinghouse.
An infusion associated with natural herb sweetened with honey was slightly laxative and encourages monthly period circulation. Materia medika Indonesia, Jilid VI. Boston, Houghton Mifflin Co., 2002. Five Chinese publications plus one Japanese log comprise handsearched. Minimal dosage of this fruits is believed to promote the nervous system whilst huge dosages depress they, while controlling the heart.
Its better for those who involve some ivy tincture in your house. Simple to prepare ivy tincture:Collect ivy leaves and stop a few of the green bark, then pass them through a mincer. When ready, press by means of a sieve, filter and bottle.A few drops of the tincture rubbed softly on a sting will begin to alleviate the pain. Additionally successful, compresses made with seawater to which a few globules of ivy tincture is added. Any of those treatments reduce puffiness and helps neutralize the toxin. In situation of hornet stings, it is advisable to see your physician. Antihistamines offered by injection or by mouth decrease later-showing symptoms. Calamine lotion helps relieve itch.
Instant granules, Ginseng liquidGinseng teas: with German chamomile teas thereby applying brand new dish. Solomon's seal was actually so named most likely from starlike marks in the rootstock, purportedly reminding you in the celebrity of David. Biotin, choline, inositol, iron, lecithin, mucilage, fickle natural oils, PABA, phosphates, proteins, trigoneline, trimethylamine, and nutrients A, B1, B2, B3, B5, B6, B9, B12, and D. If you find yourself sick, manage see a practitioner for an appointment and treatment solution.
imu A European herbal with composite umbels of smaller, white blossoms and finely separated foliage.
Preparing is extremely like carrots, and may feel crushed, boiled, as well as combined with other food stuffs. Mint grows in hydrated, shaded segments and additionally in bright places.
The natural herbs is: JAMA,v. Seed utilized to cure joint disease and endocrine system infection. The natural ingredient yahoo Gan Tang coupled with interferon-alpha confirmed notably much better impacts on approval of serum HCV RNA (general issues 2.54; 95% self-esteem period 1.43 to 4.49) as well as on normalisation of serum alanine aminotransferase task (general danger 2.54; 95% self-confidence period 1.43 to 4.49) than interferon-alpha monotherapy.
Inoue et al. The variety are explained and known as without bearing in mind whether a few of them got formerly come explained someplace. Quantity 4, that was printed during 2009, contains 28 monographs.
The next natural herbs tend to be drawn in teas for exorbitant menstrual.(to reduction stream) Listed here natural herbs tend to be used teas for tardy menstrual.
Poultice: make use of broken dried leaves, or simmer the source in milk products to obtain the correct reliability. Liquorice is actually contraindicated in instances where you will find a propensity towards water retention, edema with a high blood pressure level. The normal identity most likely are a corruption of this French esdragon, produced by the herbal's Latin certain title dracunculus, only a little dragon; p probably very known as due to the brown coiled sources similarity to a cluster of tiny, gnarled serpents.
Biochemical details Aerial section, frequently dried out dried leaves and blooming best yellowish pier was a recurrent herbal; their spindle-shaped, yellowish taproot directs upwards an easy, quite slim base, 1-5 legs highest. Berbidaceae After anattack of shingles, although the sore spots and lesions have left, the individual may go through problems, particularly in older people.
Repel fleas with oils of cedarwood, citronella, eucalyptus, pennyroyal, rue and rosemary. To prevent insect stings, use simple, light colored clothes, avoid wearing whatever is bloomed or dark.Do Not use cologne, sunscreen, hairspray or shiny jewelry. Avoid wearing sandals or loose fitting clothing. Calendula ointment is a great insect repellent and counterirritant. Avoid alcohol, this causes your skin to flush as well as the blood vessels to dilate, which brings mosquitoes and horseflies.


Does Wikipad come with Games pre-installed?
Yes. Wikipad includes great games like MadFinger's DEAD TRIGGER and SHADOWGUN: DEADZONE, Distinctive Games HOCKEY NATIONS TOURNAMENT, All for free and optimized for Wikipad's ergonomic game controller.
Why am I unable to Play Pre Installed Games?
Can I save games and apps on a micro SD card?
What games are compatible with the Wikipad controller?