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HomeOur ImpactMeet Our ResearchersMarsha A. Moses
Marsha A. Moses, PhD
Julia Dyckman Andrus Professor of Surgery
Director, Vascular Biology Program
Goal: To identify the genes that drive tumor development and growth and develop preventive strategies.
Impact: Dr. Moses is studying how dormant tumor cells – cells that survive treatment and lie sleeping in the body – become active and spread, a process enabled by certain genes and proteins. Her work could lead to new strategies for preventing breast cancer recurrence.
What's next: She and her colleagues will continue to search for biomarkers that can act as a signal when dormant tumor cells have been activated. They are also developing new drug delivery systems that targets triple negative breast cancer (TNBC), a particularly aggressive subtype of breast cancer.
Even when treatment eliminates any detectable cancer, some cancer cells escape the effects of treatment and lie dormant and undetectable in the body. Eventually, these tiny lesions of cancer can break out of their dormant state and become active, causing recurrence in the breast or other sites in the body. Dr. Moses aims to identify both the genes and proteins that activate sleeping tumor cells and biomarkers that signal tumor cell re-awakening.
Research area: Understanding the mechanisms underlying breast tumor development and progression with the goal of developing effective therapeutics, diagnostics and prognostics.
Impact: In order for a small breast tumor to establish itself, grow and metastasize, it must recruit its own blood vessels via the process called angiogenesis. In the absence of angiogenesis, a tumor will remain dormant and, often, clinically undetected. Dr. Moses is conducting studies to identify and target the genes and their proteins that regulate these processes. The information she obtains from these studies will enhance the understanding of the mechanisms underlying breast tumor development and progression and can be used to identify new biomarkers and develop new breast cancer therapies.
Current research: She and her colleagues are studying genes and their proteins that allow a dormant tumor cell to become active. They are working to further identify noninvasive biomarkers that play a role in the escape of tumor cells from dormancy. In addition, they are developing novel non-toxic drug delivery systems to specifically target the identified biomarkers in triple negative breast cancer (TNBC) patients.
What she's learned so far: Dr. Moses and her team have made significant progress in understanding the mechanisms underlying breast tumor development and progression. They have identified and validated a number of noninvasive biomarkers that can be used to detect the presence of breast cancer, its progression and metastasis.
What's next: Her research team will continue their work on a novel drug delivery system to specifically target TNBC incorporating findings from her current studies. Dr. Moses will also utilize the newly discovered biomarkers to non-invasively and continuously monitor drug response and inform prognosis.
Dr. Marsha A. Moses is the Julia Dyckman Andrus Professor at Harvard Medical School and the Director of the Vascular Biology Program at Boston Children's Hospital. She has made significant contributions to our understanding of the biochemical and molecular mechanisms that underlie the regulation of tumor growth and progression. Dr. Moses and her laboratory have discovered a number of inhibitors of neovascularization that function at both the transcriptional and translational level some of which are being developed for potential clinical use in a variety of human diseases. Named a pioneer in the field of Biomarker Medicine by the Journal of the National Cancer Institute, Dr. Moses established a Proteomics Initiative in her laboratory to complement this work which has led to the discovery of panels of noninvasive urinary cancer biomarkers that can predict disease status and stage in cancer patients and that are sensitive and accurate markers of disease progression and therapeutic efficacy of cancer drugs. To complement these studies, she created a Proteomics Initiative at Boston Children's Hospital and has utilized its resources, including an extensive human biorepository and her significant expertise in proteomics, to discover and validate a number of novel, non-invasive, urinary biomarkers for a variety of human cancers as well as non-neoplastic diseases. A number of these biomarkers are being used in clinical trials. To complement her basic and translational findings, she and her team have engineered novel non-toxic, targeted nanomedicines for the treatment of human cancers and their metastases. These drug delivery systems are engineered to deliver a variety of therapeutic agents including siRNAs, chemotherapies and gene editing systems. A number of these diagnostics and potential therapeutics are included in Dr. Moses' significant patent portfolio composed of both US and foreign patents.
Dr. Moses' basic and translational work has been published in such journals as Science, The New England Journal of Medicine, Cell, and Nature Communications, among others. Marsha received a Ph.D. in Biochemistry from Boston University and completed a National Institutes of Health postdoctoral fellowship at Boston Children's Hospital and MIT in the laboratory of Dr. Robert Langer. She is the recipient of a number of NIH and foundation grants and awards. Dr. Moses has been recognized with both of Harvard Medical School's mentoring awards, the A. Clifford Barger Mentoring Award (2003) and the Joseph B. Martin Dean's Leadership Award for the Advancement of Women Faculty (2009). In 2014, she received the Excellence in Mentoring Award from the Postdoc Association of Boston Children's Hospital and in 2016, she received their award for Exceptional Mentorship. In 2013, Dr. Moses received the Honorary Member Mentoring Award from the Association of Women Surgeons of the American College of Surgeons. Dr. Moses was elected to the Institute of Medicine (National Academy of Medicine) of the National Academies of the United States in 2008, the National Academy of Inventors in 2013 and the American Institute for Molecular and Biological Engineering in 2018.
The Hale Family Award
Heredity & Ethnicity


Before I start this I have to say something to you guys who are reading this. I am so sorry because of the images in reverse. I'll try to stop this evilness(?) from happening.
So this is a really easy to make armor. It only took me 30 minutes to make it (although its shoulders are not really resistant).
So for the body part, you will need 2 cardboard plates that cover your chest and part of your stomach (both of them).
After that, roll both plates and undo it. This will make the plate fit on your body.
Then, cut both of them as shown on the 4th picture. Cut it in a way that it makes your arms and neck move freely.
Get 2 plates that cover your shoulder and a bit more. Make them round as you did with the chest. Connect the 2 of them with string, just remember, dont make it thight.
Connect the body plates together so it protects both front and back of your body. Put the shoulders on the body and tape it. Make it rigid.


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Bakken Leak Puts Spotlight on Fast-Growing Crestwood Midstream
A leak of brine from a North Dakota pipeline places a spotlight on a fast-growing pipeline outfit.
Dana Blankenhorn
NEW YORK (TheStreet) -- Pipelines are the safest way to move oil and gas from a field to market. Breaks are uncommon, but each break is a potential catastrophe.
One such break came over the July 4 weekend in a saltwater line owned by a unit of Crestwood Midstream Partners (CMLP) , putting an unwanted spotlight on the Houston-based company.
The underground line contained brine from fracking operations. The brine is between 10 and 30 times saltier than sea water. Some of the roughly 1 million gallons of brine lost got into Bear Den Bay in North Dakota. The bay leads to a lake that supplies water for a local Indian tribe, according to press reports.
Greenberg: No Surprise in Potbelly's Flop
Link: Waddell & Reed Offers Growth at a Nice Price
Bear Den Bay feeds the Missouri River, and the leak took a week to find because the line did not have electronic monitoring.
Crestwood had just finished plugging some major financial leaks when the leak occurred.
Those came from the acquisition of Inergy, a larger pipeline operator bought in June, 2013, and Arrow Midstream, acquired in October.
The two deals make Crestwood a major player in the Bakken, an oil and gas play centered in western North Dakota that produced 937,263 barrels of oil per day in April, according to state figures, nearly 10 times the production level of early 2009.
The two deals have put a substantial leak in Crestwood finances, which the company is also trying to clean up. After booking $69 million in revenue for the quarter ending in September, 2013, Crestwood had $658.6 million in revenue during the fourth quarter.
That fell to $537 million for the March quarter, but the bottom line swung from a net loss of $20 million in December to a net profit of $2.4 million for March. Crestwood is due to report results for the June quarter on Aug. 5. The balance sheet currently shows a little more than $1 in debt for each $4 in assets.
After the acquisition of Inergy and Arrow the per-share dividend was cut from 51 cents to 41 cents, but even at the present level the stock is yielding 7.5%. A recent $500 million preferred equity placement, which included a unit of GE's (GE) - Get ReportGE Energy Financial Services, will ease any cash crunch. The units pay 58 cents per quarter in either cash or stock.
The company has also had insider trading on both the buy and sell sides recently.
John Sherman, who was Crestwood's CEO before the Inergy deal and remains a director, has been selling his stock. At the same time independent director David Lumpkins, executive chairman of PetroLogistics (PDH) , a chemical company being acquired for $2.1 billion by a unit of privately held Koch Industries, was buying shares. News of the Sherman sales brought in the shorts, but the Lumpkins sales seem to have many covering.
A return to normalcy could be a big plus for Crestwood shareholders, with the stock having lost 12% of its value since the start of the year, almost double the dividend rate. When pipelines stay strong, earnings do as well. And when you have a big piece of the market, as Crestwood does in the Bakken, earnings can stand strong as well.
We reached out to Crestwood for comment on all these matters but had received none by press time.
At the time of publication the author owned shares of GE.
Follow @danablankenhorn
This article represents the opinion of a contributor and not necessarily that of TheStreet or its editorial staff.
OpinionInvestingOilOil Equipment/Services
By Eric Jhonsa
Procter & Gamble Tops Q2 Earnings Forecast, Boosts 2021 Guidance: Shares Jump
20 Realistic Tech Predictions for 2021 (Part One)
Trump Pardons Google Trade Secret Stealer Anthony Levandowski
Netflix Shares Soar As Subscribers Pass 200 Million Amid Q4 COVID Watching Binge
Do You Need Permanent Life Insurance? Probably Not—This Is Why
By NerdWallet
Alibaba Jumps as Jack Ma Resurfaces After Three Months

redpajama_set_name: RedPajamaCommonCrawl


text:
és un mestre jubilat i poeta en actiu. Ha viscut a Artés i a Manresa, però actualment s'està a Calders, d'on és regidor de Cultura.

Com a poeta, debutà l'any 2004 amb Postals de Calders. L'han anat seguint una sèrie de títols publicats associats a diversos premis literaris. A més, és autor de diversos poemaris no publicats, però també reconeguts en premis literaris.

Obres

 Postals de Calders (2004)
 Camins d'hivern (2008)
 Sis dies d'agost (2009)
 D'aquí estant (no) es veu la mar (2010)
 Bages (2010)
 Parlo d'Aloma (2010)
 Natana, premi Miquel Martí i Pol (2010)
 L'altra veu (2011)
 Ingènuament protocol·lari (2011)
 Les hores vives (2012)
 El mar dels altres (2012)
 I la llum es va fer (2013)
 Guanya la dama (2013)
 Perquè fossis més meu (2014)

Poemaris no publicats reconeguts en premis literaris

 Vora l'aigua, premi Terra de Fang, Deltebre (2007)
 Miniatures, premi Ciutat de Terrassa (2007)
 Obsedit, premi Montseny (2008)
 Lluna vella, premi Terra de Fang, Deltebre (2008)
 Esgarips, premi Sant Jordi de Santa Bàrbara (2008)
 Nu, premi literari Homilies d'Organyà (2009)
 Camins de llum i de fang, premi Sant Jordi de Santa Bàrbara (2010)

Referències

Suriencs
Escriptors bagencs contemporanis en català
Poetes catalans del sud contemporanis en català
Premis literaris Ciutat de Badalona
Calderins

redpajama_set_name: RedPajamaWikipedia


text:
Global trends: climate change and resilience within contaminated lands rehabilitation
W.D. Wick, B. Maco, Richard Bardos, L. Hansen, E. Mielbrecht, T. Yasutaka
Hurricanes Harvey and Maria demonstrated the impacts that climate change can have on contaminated lands—impacts that can threaten public health and the environment. Sites were inundated by floodwaters, releasing contaminants and exposing residents, first responders, and the regions' fragile ecosystems to harmful levels of toxins. These threats can exist even on contaminated land which has been remediated to regulatory requirements.
According to a 2017 analysis by the Associated Press, nearly two million people, the majority in low income communities, live within one mile of one of 327 Superfund sites in areas prone to flooding or vulnerable to sea-level rise caused by climate change., See Jason Dearen, et al., AP Finds Climate Change Risk for 327 Toxic Superfund Sites, Associated Press, Dec. 22, 2017.
https://www.americanbar.org/groups/environment_energy_resources/publications/natural_resources_environment/2018-19/fall/global-trends-climate-change-and-resilience-within-contaminated-lands-rehabilitation/
Dive into the research topics of 'Global trends: climate change and resilience within contaminated lands rehabilitation'. Together they form a unique fingerprint.
contaminated land Earth & Environmental Sciences 100%
Superfund Earth & Environmental Sciences 96%
rehabilitation Earth & Environmental Sciences 72%
Jason Earth & Environmental Sciences 50%
climate change Earth & Environmental Sciences 43%
toxin Earth & Environmental Sciences 39%
climate change impact Earth & Environmental Sciences 38%
trend Earth & Environmental Sciences 37%
Wick, W. D., Maco, B., Bardos, R., Hansen, L., Mielbrecht, E., & Yasutaka, T. (2018). Global trends: climate change and resilience within contaminated lands rehabilitation. Natural Resources & Environment, 33(2), 16. https://www.americanbar.org/groups/environment_energy_resources/publications/natural_resources_environment/2018-19/fall/global-trends-climate-change-and-resilience-within-contaminated-lands-rehabilitation/
Wick, W.D. ; Maco, B. ; Bardos, Richard et al. / Global trends : climate change and resilience within contaminated lands rehabilitation. In: Natural Resources & Environment. 2018 ; Vol. 33, No. 2. pp. 16.
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In: Natural Resources & Environment, Vol. 33, No. 2, 15.11.2018, p. 16.
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T2 - climate change and resilience within contaminated lands rehabilitation
AU - Wick, W.D.
AU - Maco, B.
AU - Bardos, Richard
AU - Hansen, L.
AU - Mielbrecht, E.
AU - Yasutaka, T.
N2 - Hurricanes Harvey and Maria demonstrated the impacts that climate change can have on contaminated lands—impacts that can threaten public health and the environment. Sites were inundated by floodwaters, releasing contaminants and exposing residents, first responders, and the regions' fragile ecosystems to harmful levels of toxins. These threats can exist even on contaminated land which has been remediated to regulatory requirements. According to a 2017 analysis by the Associated Press, nearly two million people, the majority in low income communities, live within one mile of one of 327 Superfund sites in areas prone to flooding or vulnerable to sea-level rise caused by climate change., See Jason Dearen, et al., AP Finds Climate Change Risk for 327 Toxic Superfund Sites, Associated Press, Dec. 22, 2017.
AB - Hurricanes Harvey and Maria demonstrated the impacts that climate change can have on contaminated lands—impacts that can threaten public health and the environment. Sites were inundated by floodwaters, releasing contaminants and exposing residents, first responders, and the regions' fragile ecosystems to harmful levels of toxins. These threats can exist even on contaminated land which has been remediated to regulatory requirements. According to a 2017 analysis by the Associated Press, nearly two million people, the majority in low income communities, live within one mile of one of 327 Superfund sites in areas prone to flooding or vulnerable to sea-level rise caused by climate change., See Jason Dearen, et al., AP Finds Climate Change Risk for 327 Toxic Superfund Sites, Associated Press, Dec. 22, 2017.
JO - Natural Resources & Environment
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We can help you select the right treatment center - therapy and medical support often help addicts build tools and coping mechanisms to maintain sobriety. Detoxing from substances after consuming them addictively in Lakehead, California can be trying - because of the familiarity of using, many are afraid to go without. Detoxes.net exists to provide resources for addicts and loved ones. Embarking on the process of detoxification can be made simpler our website gives those who are addicted as well as their loved ones the ability to search treatment directories, we give addicts and their families the ability to pick the best medical detox in Lakehead, California. This process gives users the capacity to browse detox options across the Country this service assures chosen detoxes are suitable for each family and individual suffering with addiction. Call or enlist the help of detoxes.net to locate the right rehab facility for you or your addict in Lakehead, California.
Do not forget, when you are pursuing treatment options in Lakehead, California, to see the quality of the detox or treatment center as well as peruse its references. Regardless of geographical locations or other limitations, many a residential detox and treatment facility options are available to you - Detox and treatment will ensure you are able to achieve sobriety. We are here to guide you in searching for the right addiction treatment center - the rehab journey will be dependent upon your requests. Detoxes.net can get you on the road to abstinence. Not all addiction treatment centers in Lakehead, California will provide appropriate or helpful treatment, subsequently you want to be scrutinous. It is important to take the time to do your research. You may be suffering if you or your loved one can't locate the right treatment facility in Lakehead, California, Visit our website for more information.
When detoxing the individual is usually given a lower dosage or tapered off using medically assisted drugs such as Suboxone for Opiate withdrawal or Ativan for Alcohol withdrawal,During the painful process of detox and withdrawal, many addicts receive drugs to taper them off, tapering helps to make sure the patient is safe and in minimal discomfort. Tapering is overseen by the staff at your addiction treatment center Lakehead, California. Once you find a detox center in Lakehead, California you are on your way to sobriety, It will help a patient leave behind their old life of drugs and alcohol. About all Medical Detoxes in Lakehead, California are about a week long, this varies based on the type of drug used, plus the amount and frequency with which it was ingested. Inpatient addiction treatment in Lakehead, California provides patients with mental health evaluations and treatments, Detoxes, conversely, offer more short-term, physical solutions. Upon leaving detox in Lakehead, California individuals are moved to a lower level of care- The transition to long-term treatment gives addicts larger chances of obtaining freedom.


Baby Flapjacks are the PJs that every nursery needs! Cradling the body in snug comfort, Flapjacks provide stretchable movement, cozy warmth, and handy snaps between the legs for easy diaper access. And speaking of baby "booties," each Flapjack comes with a (decorative only!) trapdoor to cover those sweet cheeks! When it comes to comfort, baby Flapjacks are just the right formula.


Three and a half moths of shawl shapes. 16 posts.
That's a lot of shapes. But the craziest thing is that it's just the beginning. Seriously.
I'm in the middle of editing a second ebook with 18 more shapes for shawls. Because you can always explore deeper and play more.
So do it. Take these shapes and play! Experiment! Design stuff!
The beginning of the series is here, with links to all the posts.
And if you really loved the blog series. Buy the ebook. Get all the information in one place, and help ensure that I can create more "teachy" blog posts.
Or sign up for the Announce! Announce! list. And be the first to hear about Shawl Geometry II when it becomes available.
I just found this post after searching… and searching for a formula for the pi shawl. WOW!! I'm so glad I did! wish I would have found it sooner. I stayed up most of the night reading through your blog, absolutely amazing… I can't wait to have some time to try out all the different shapes! I WILL be buying those ebooks asap! Thank you so much for all the time you have spent doing this. I can't wait to create!!
I'm so glad you enjoy it!! And I hope it helps you in your knitting! Thank you for leaving such a sweet comment.


Why bother with a shaving brush at all? Shaving brushes are used to stir shaving soap, as opposed to the aerosol canned shaving creams that burst forth with lather. The process of applying the brush with water and foamy lather to your face exfoliates your skin. Shaving with a brush and soap softens your beard, and distributes the lather evenly. It also helps lift your hair away from your skin if you decide that you are ditching the beard and mustache trimmer in favor of a cleaner look.
Why do these things matter? Well, compared to using shaving cream with your fingers, which can matte your facial hair, clump it, and is difficult to evenly distribute, having the hair lifted means you don't have to scrape the safety razor so hard against your skin. It also reduces nicks and cuts that commonly occur when you hand-apply shaving cream. So, for a smooth, even shave, using a shaving brush is your best bet.
What's the Real Deal with Shaving Brushes?
Well that makes total sense to us, but there are so many options to choose from out there! We are going to set the facts straight for you and let you in on some nice info before we tell you about some best shaving brushes.
You may or may not know this, but there are several different types of bristle options for shaving brushes. Yep, there are bristle fibers made from boar, badger and horse hair. The prices will vary based upon the hair type and even the handle that's hanging onto the bristles.
Boar hair is pretty thick and is pretty common as well as easily found. It is also less expensive than some other options. Badger hair is out there too and it's kind of like the jack of all trades of shaving brushes. It's versatile and the silky nature of badger hair makes the quality rather nice too. Each type of bristle has its own softness, durability and longevity to look out for as well. You'll ultimately want something that fits into your shave routine the best.
We will expound upon this more in just about, so don't go anywhere.
Each type of bristle and brush style you use will have a specific way that it should be used. You will first want to soak the brush in some hot water and then do your best to remove any excess water hanging out at the top of the hairs. Get busy whisking away in your shaving mug (or bowl if that floats your boat). This should result in a nice lather that you can then apply to your face. Most guys like to use a sort of flicking and massage method that helps your whiskers stand away from your face and gives your face a gentle exfoliation.
Keep in mind the type of bristle you have when selecting your shave soap or shave cream as well. Boar bristle shave brushes are ideal for solid shaving soaps. The rigid nature of the hairs helps to work up a great lather. Badger bristle shaving brushes are better suited for creamer shave soaps or creams. The bristles are generally softer and have pretty excellent heat retention, so your resulting lather usually has a better hold and is thicker.
How Do I Care for My Shave Brush?
It's important to rinse your shaving brush really well after each use and wash it. Once you've made sure that all off the shave soap is out and it's clean, go ahead and hang it upside down. Hanging it upside down ensures that all of the extra water that hangs onto the bristles has a place to go and will also allow you to maintain sterility. Proper care for your shave brush will ensure that it lasts for a long time and maintains its performance integrity.
What kinds of shaving brushes are there?
As you will see from our table, the prices can range from $12 to $120, and higher. So, how do you know which one you'll like? One thing you can do is consider whether you want softness or briskness against your face. Some people with sensitive skin want soft bristles. Others want a brush they can really feel against their skin, opening their pores. Those are only a couple of things to consider. There are about four standard types of shaving brush: badger hair, boar hair, synthetic, and horse hair. Let's take them one by one.
Badger hair shaving brushes are considered by some to be the gold standard in shaving brushes.They hold a lot of water, make a good lather, and release that water and lather easily to your face. The main differences between the really expensive ones and the cheaper ones are the thickness and fullness of the bristles, where it's made, whether it's handmade, whether or not it's silver-tipped (those bristles come from the softest part of the badger– the underbelly), and what kind of handle it has. Some people like the feel of the wood handle, but those can rot over time. Acrylic handles are nice to prevent rot. But the real key with all shaving brushes is that you have to hang them up or they won't dry.
Badger hair does take some time to dry. It may also have a slight gamey odor at first (until it really starts to absorb the smell of your soap). The Premium Black Pure Badger Shaving Brush By Wet Shaving Products seems to be a good deal at a reasonable price ($25-$44). You can get a $12 badger brush, but if you are going to invest in a badger brush rather than synthetic, why go with the cheapest (which won't have as much fullness and may shed more)?
The scent seems to be the main issue with not using these brushes. However, they are popular (the Omega brush in particular seems to be well-liked). Boar brushes are coarser than badger brushes. This can mean less softness against the skin, but also a firmer shape than the badger brushes. Some people claim this creates a better lather.
The bristles are scratchier against the skin than badger brushes, so again, it comes down to personal preference. Boar brushes also need to be soaked in hot water for about ten minutes before use, so you will need to plan accordingly. The bristles do soften over time. Boar brushes have a tendency to shed their hair more than badger hair, but the shedding is generally minimal. These brushes last a long time. Among the boar brushes, the price and durability of the Omega Pro 48 brush ($11-$18) make it hard to beat.
For animal lovers, or anyone who does not like the idea of putting animal hair against their face daily (and those particularly sensitive to a gamey odor), there are a lot of good synthetic brushes out there to choose from. In addition to having the softness of badger bristles, synthetic brushes are less floppy than badger brushes. However, they are less scratchy than boar or horse hair brushes. They produce a good lather, and although they may not release water as easily as the badger brushes, they will still give you a good shave.
One of the best things about the synthetic brush is that it dries much faster than the animal hair brushes. The Parker Safety brush has a very nice price (about $25), free stand, and boasts a full brush with soft bristle tips. However, the Frank brush has the same price (at the moment), also comes with a stand, and has earned a five-star rating on Amazon.
Horse hair brushes are not for the faint of heart. These brushes are going to have a stronger odor than any of the other brushes, and it can last for a few days. Once you get past the smell, you'll find that horse hair brushes are softer than boar hair, but stiffer than badger hair, so you get the best of both worlds. You will also find that the horse hair brushes do not need to be soaked as long as the boar brushes before you use them.
There aren't a ton of horse hair brushes to choose from, but the Vie-Long 13061 Horse Hair Shaving Brush is well-reviewed. The horse hair brushes are also affordable, with most of them running about $30. You might also consider a more costly horse/badger shaving brush, if you are curious about horse hair, but more interested in the badger hair brush.


We're happy to announce that we - Wooden Horse Corporation - will be attending Equine Affaire this year in Columbus, Ohio from April 11-14th! This will be the first year in quite a few that we will have our very own booth and we are so excited. We will be bringing along a couple of Equicizers as well as some of our new accessories such as the All Purpose Riding Pad and Elastic Rein Attachments, which will be on display and available to see and try.
Equine Affaire is still over two months away but we wanted to get this out there as soon as possible for those who will need to make work and/or travel arrangements. Over the next couple of months we will be releasing more information concerning our booth location (we're in a great spot!), potential discounted products, and more.
We hope to see your smiling faces there!!
Below: Equine Affaire 2017 at Steve Lantvit's booth.
We hope you were able to tune into Big Brother on Wednesday, January 23rd to see the episode they taped featuring six Equicizers in one of the show's Veto Competitions!
The unique challenge required participants to ride the Equicizer in between bouts of stacking and balancing horse shoes. It was interesting to hear a contestant comment on how much more difficult it was to ride the horse than he imagined. Congratulations to former Miami Dolphins running back Ricky Williams on his victory!
If you missed it, here are some pictures and a clip from the big night on reality TV. Other participants in the challenge include comedian Tom Green, politician Anthony Scaramucci, Olympic swimmer Ryan Lochte, actor Joey Lawrence, and actor Jonathan Bennett.
Make sure to follow us on Facebook, Instagram, and Twitter (links below) so you know when to tune in for these type of Equicizer special appearances!
Of the Equicizers featured on the show, 2 are still available for purchase and we are offering them at a 10% discount! Some of the colors left are not typical Classic Equicizer colors, so this is a unique opportunity in more ways than one. Please contact us at info@equicizer.com if you are interested!
If you missed it, be sure to check out our latest blog post "Facts, Figures, and Fun!". Before you scroll down, answer the questions at the beginning and then see how your answers compare to our actual facts and figures! This blog post was a fun look into the presence and customer base of the Equicizer brand.
Subscribe Today! If you want the Equicizer Newsletter sent directly to your inbox each month, head over to our website to enter your email and subscribe! We only send a monthly newsletter and once in a while special announcements.


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Home › The Life of Catherine de Hueck Doherty
The Life of Catherine de Hueck Doherty
Booklet - $4.00 - $4.00 USD Quantity
Foundress of Madonna House Apostolate
Get the set of all three "Pioneer Series" booklets at a special price!
Because of Christ, Catherine's life is a love story. "I am in love with God and that is a fact," she would say.
The life of Catherine de Hueck Doherty is an adventure story through two World Wars, the Russian Revolution, the Great Depression, the Civil Rights movement in the U.S., and the Second Vatican Council. Yet more than all that—the life of Catherine Doherty is a love story.
Born into aristocratic wealth, Catherine experienced grinding poverty as a refugee. She went from riches to rags, and eventually back to riches, in North America. Then inexplicably, she reverted to poverty, voluntarily giving away her possessions and living in the slums to work with the poor and destitute—all for the sake of the Gospel of Jesus Christ.
Because of Christ, Catherine's life is a love story. "I am in love with God and that is a fact," she would say. How this love story unfolded to include the lay apostolate of Friendship House—and later Madonna House—is contained in this booklet.
Initial steps in the canonization process are currently underway to determine if Catherine Doherty might one day be declared a saint in the Catholic Church.
About the author Mary Bazzett About Catherine Doherty
46 pages — Booklet, 5″ x 8″ — Madonna House Publications, 1998
A Cricket in My Heart: An Autobiography
Paperback - $14.95
eBook - $8.95
A Hermit Without a Permit
An Experience of God: Identification with Christ—A Road to the Mystical Life
Paperback - $9.95
Catherine de Hueck Doherty: aventurière ou sainte?
Paperback - 53,95 $
Desert Windows


text:
import _extends from "@babel/runtime/helpers/esm/extends";
import * as React from 'react';
import PropTypes from 'prop-types';
import { deepmerge } from '@material-ui/utils';
import useThemeProps from '../styles/useThemeProps';
import GlobalStyles from '../GlobalStyles';
import { jsxs as _jsxs } from "react/jsx-runtime";
import { jsx as _jsx } from "react/jsx-runtime";
export const html = {
  WebkitFontSmoothing: 'antialiased',
  // Antialiasing.
  MozOsxFontSmoothing: 'grayscale',
  // Antialiasing.
  // Change from `box-sizing: content-box` so that `width`
  // is not affected by `padding` or `border`.
  boxSizing: 'border-box',
  // Fix font resize problem in iOS
  WebkitTextSizeAdjust: '100%'
};
export const body = theme => _extends({
  color: theme.palette.text.primary
}, theme.typography.body1, {
  backgroundColor: theme.palette.background.default,
  '@media print': {
    // Save printer ink.
    backgroundColor: theme.palette.common.white
  }
});
export const styles = theme => {
  const defaultStyles = {
    html,
    '*, *::before, *::after': {
      boxSizing: 'inherit'
    },
    'strong, b': {
      fontWeight: theme.typography.fontWeightBold
    },
    body: _extends({
      margin: 0
    }, body(theme), {
      // Add support for document.body.requestFullScreen().
      // Other elements, if background transparent, are not supported.
      '&::backdrop': {
        backgroundColor: theme.palette.background.default
      }
    })
  };
  const themeOverrides = theme.components?.MuiCssBaseline?.styleOverrides;

  if (themeOverrides) {
    return deepmerge(defaultStyles, themeOverrides);
  }

  return defaultStyles;
};
/**
 * Kickstart an elegant, consistent, and simple baseline to build upon.
 */

var _ref = /*#__PURE__*/_jsx(GlobalStyles, {
  styles: styles
});

function CssBaseline(inProps) {
  const props = useThemeProps({
    props: inProps,
    name: 'MuiCssBaseline'
  });
  const {
    children
  } = props;
  return /*#__PURE__*/_jsxs(React.Fragment, {
    children: [_ref, children]
  });
}

process.env.NODE_ENV !== "production" ? CssBaseline.propTypes
/* remove-proptypes */
= {
  // ----------------------------- Warning --------------------------------
  // | These PropTypes are generated from the TypeScript type definitions |
  // |     To update them edit the d.ts file and run "yarn proptypes"     |
  // ----------------------------------------------------------------------

  /**
   * You can wrap a node.
   */
  children: PropTypes.node
} : void 0;
export default CssBaseline;

redpajama_set_name: RedPajamaGithub


text:
Home > Relationships / Communication > Couples Communication: Learn Each Other's Styles
Understanding each other's styles and learning to adapt your own can help ward off conflict.
Clashing communication styles can cause problems in relationships. These differences may be rooted in age, sex, upbringing, and your culture. That doesn't mean you can't change, however. Understanding each other's styles and learning to adapt your own can help ward off conflict.
Direct versus indirect
The person with a direct communication style gets right to the point. She asks for what she needs. For example, "I want you to be home for dinner from now on." Indirect communicators don't ask directly. They might say, "The neighbors have dinner together every night. Isn't that nice?"
Both types of communication styles can cause problems. Direct communicators can come across as demanding or blunt. Indirect communicators are more likely to be misunderstood. They tend to be vague in saying what they mean.
What to do: Couples with these two different styles can learn to meet near the middle. A direct speaker might soften requests and statements. The other partner can learn to be more direct. A good middle ground for both might be, "I value our time together. Will you try to get home in time for dinner so we can eat as a family?"
Collaborative versus goal-oriented
The collaborative partner sees conversation as a way to connect. The goal-oriented partner uses it to give information, solve problems, and show expertise. The former tends to ask for others' opinions before making a decision. The latter might think through the problem privately. Then she might make up her own mind about it.
These two communication styles in a relationship can cause hurt and frustration. The collaborative partner enjoys talking as a way to feel closer. He may feel shut out by the other's silence. He may feel left out of decision making. The goal-oriented partner may feel his partner is indecisive. He may not have the patience for lots of talk.
What to do: Talk with each other about your different styles. The collaborative partner should recognize the other's need for information. He can leave out unnecessary details and get to the point sooner. The goal-oriented partner should include the other in decisions. She might also share more about her days and talk about what's on her mind
Hot versus cold
This refers more to styles of dealing with conflict, rather than relating. But it certainly can cause strife in a relationship. One partner wants to deal with conflict right away. The other wants time to collect her thoughts or cool off. The partner who wants to resolve the issue at once is likely to feel rejected. The other partner feels attacked.
What to do: Talk with one another about what underlies your conflict styles. The partner with the "hot" conflict style may feel anxious when a dispute goes unresolved. The one with the "cold" conflict style may feel anxious when arguments become heated. You might agree on a short time-out. Both partners should speak calmly and take turns listening to each other.
Remember, there is no one right way to communicate. A key to feeling understood and supported in a relationship is to learn each other's communication styles. That will allow both of you to make adjustments and speak each other's language.
By Sharron Luttrell, Military OneSource. Used with permission.
9999 ENGLISH DEFAULT 202 3 50220 / N 1 N N/A www.achievesolutions.net https://www.achievesolutions.net/achievesolutions/en/Content.do?contentId=50220&topicId=734&centerId=43


Boston Benefits Consulting is located at 100 Main St, Concord, MA. This business specializes in Business to Business.
Since 1981, Boston Benefits Consulting, Inc. has been providing Actuarial Consultant from Concord.


text:
Displaying 1 - 25 of 56 items.
Landrum Brewer Shettles (1909-2003)
Landrum Brewer Shettles is remembered as an important contributor to early in vitro fertilization research in the United States as well as a prolific author on the subject of choosing a child's sex before conception. Shettles was born in Pontotoc County, Mississippi on 21 November 1909 to Sue Mounce and Brazil Manly. Shettles trained and worked as a gynecologist at Columbia University Presbyterian Medical Center, after receiving his MD in 1943 from Johns Hopkins University.
Georgeanna Seegar Jones (1912-2005)
Georgeanna Seegar Jones was a reproductive endocrinologist who created one of America' s most successful infertility clinics in West Virginia and eventually, along with her husband Howard W. Jones MD, performed the first in vitro fertilization in America, leading to the birth of Elizabeth Jordan Carr. Jones was born in Baltimore, Maryland, on 6 July 1912. Her father, Dr. John King Beck Emory Seegar, was a practicing physician at the time working in the field of obstetrics.
José Pedro Balmaceda (1948- )
José Pedro Balmaceda was born 22 August 1948 in Santiago, Chile. His mother Juanita owned a women's boutique in the city and his father José was a successful owner of several timber mills. He grew up with five sisters who remained in Santiago all their lives. Balmaceda attended the college preparatory school San Ignatius where he met Sergio Stone, his future partner at the Center for Reproductive Health fertility clinic in the University of California Irvine Medical Center.
Howard Wilber Jones Jr.
Howard Wilber Jones Jr. and his wife, Georgeanna Seegar Jones, developed a method of in vitro fertilization and helped create the first baby in the US using that method. Though the first in vitro baby was born in England in 1978, Jones and his wife's contribution allowed for the birth of Elizabeth Carr on 28 December 1981. Jones, a gynecologist and an obstetrician, researched human reproduction for most of his life.
Sergio Cereceda Stone (1942- )
Sergio Cereceda Stone was born 16 April 1942 in the coastal city of Valparaiso, Chile. Stone's mother Luz was a housewife and caretaker for Sergio and his younger brother Lionel; his father Sergio served among the country's twenty appellate court judges. In the early 1950s Stone's father relocated the family to Santiago to further his law career.
Subject: People, Ethics, Reproduction
Zhang Lizhu (1921- )
Zhang Lizhu is a Chinese gynecologist and researcher. For most of her career, she worked in the Peking Medical College Third Hospital, renamed in 2000, Peking University Third Hospital. There, she led a team of researchers and physicians in the study of human in vitro fertilization (IVF) and embryo transfer (ET) technology. Zhang and her colleagues contributed to the birth of the first test-tube baby in Mainland China in 1988.
John Charles Rock (1890-1984)
Born on 24 March 1890 in Marlborough, Massachusetts, to Ann and Frank Rock, John Charles Rock was both a devout Catholic and one of the leading investigators involved in the development of the first oral contraceptive pill. In 1925 he married Anna Thorndike, with whom he later had five children. He spent over thirty years of his career as a clinical professor of obstetrics at Harvard Medical School, and in 1964 the Center for Population Studies of the Harvard School of Public Health established the John Rock Professorship.
Jeffrey Keenan (1961- )
Jeffrey Keenan is the Director of the Southeastern Center for Fertility and Reproductive Medicine and the main developer behind the National Embryo Donation Center (NEDC) in Knoxville, Tennessee. This non-profit organization focuses on embryo donation and embryo adoption.
Robert Geoffrey Edwards (1925-2013)
Robert Geoffrey Edwards worked with Patrick Christopher Steptoe to develop in-vitro fertilization (IVF) techniques during the 1960s and 1970s in the United Kingdom. Louise Brown, the world' s first "test-tube baby," was born as a result of Edwards and Steptoe's IVF techniques in 1978, and since then more than four million children have been born using IVF techniques. Publicity and controversy accompanied Edwards and Steptoe's work as conservative religious institutions expressed concern over the morality of the IVF procedure.
Edwin Carlyle (Carl) Wood (1929–2011)
Edwin Carlyle Wood, also known as Carl Wood, was a physician who helped develop in vitro fertilization, or IVF, treatments. From 1964 to 1992, Wood worked as a professor of obstetrics and gynecology at Monash University in Melbourne, Australia, where he was one of the first in the world to lead a team of physicians to establish IVF as a proven treatment for infertility. IVF refers to a medical procedure in which scientists inseminate an egg cell with a sperm cell outside of the body, such as in a glass dish in a clinical setting.
Subject: People, Technologies, Reproduction
John Hunter (1728–1793)
John Hunter studied human reproductive anatomy, and in eighteenth century England, performed one of the earliest described cases of artificial insemination. Hunter dissected thousands of animals and human cadavers to study the structures and functions of organ systems. Much of his anatomical studies focused on the circulatory, digestive, and reproductive systems. He helped to describe the exchange of blood between pregnant women and their fetuses. Hunter also housed various natural collections, as well as thousands of preserved specimens from greater than thirty years of anatomy work.
Gregory Goodwin Pincus (1903-1967)
Gregory Goodwin Pincus, one of the original researchers responsible for the development of the first oral contraceptive pill, was born in Woodbine, New Jersey, on 19 April 1903 to Russian Jewish parents. In 1924 Pincus received his BS degree from Cornell University, and in 1927 he received his MS and PhD from Harvard University, having studied under William Ernest Castle and William John Crozier.
Pope John Paul II (1920-2005)
Pope John Paul II's views on abortion and embryology have been very influential to the Roman Catholic Church. He strictly forbade abortion and other threats to what he regarded as early human life in his encyclical entitled "Evangelium Vitae," meaning the "Gospel of Life." His authority on moral and social issues was highly regarded during his lifetime.
Subject: People, Religion, Reproduction
Pope Pius XII (1876-1958)
Pope Pius XII was born Eugenio Maria Giuseppi Giovanni Pacelli on 2 March 1876 in Rome, Italy, to Virginia and Filippo Pacelli. Known for his oft-disputed role in the Roman Catholic Church's approach to the Nazis and World War II, Pope Pius XII also contributed a number of important documents regarding conception, fertility, abortion, and reproductive control to the Vatican's collection of writings and doctrine on procreation.
Patrick Christopher Steptoe (1913-1988)
Patrick Christopher Steptoe was a British gynecologist responsible for major advances in gynecology and reproductive technology. Throughout his career Steptoe promoted laparoscopy, a minimally invasive surgical technique that allows a view inside the abdominal cavity, successfully advancing its usefulness in gynecology. After partnering with embryologist Robert Edwards in 1966, the pair performed the first in vitro fertilization in humans.
Elinor Catherine Hamlin (1924- )
Elinor Catherine Hamlin founded and helped fund centers in Ethiopia to treat women affected by fistulas from obstetric complications. Obstetric fistulas develop in women who experience prolonged labor, as the pressure placed on the pelvis by the fetus during labor causes a hole, or fistula, to form between the vagina and the bladder (vesicovaginal fistula) or between the vagina and the rectum (rectovaginal fistula). Both of those conditions result in urinary or fecal incontinence, which often impacts womenÍs social status within their communities.
Leon Chesley (1908-2000)
Leon Chesley studied hypertension, or high blood pressure, in pregnant women during the mid-twentieth century. Chesley studied preeclampsia and eclampsia, two hypertensive disorders found in approximately five percent of all US pregnancies. In New Jersey and New York, Chesley devoted over forty years to researching preeclampsia and eclampsia. Chesley conducted several long-term studies using the same group of women beginning from their pregnancies.
Min Chueh Chang (1908-1991)
As one of the researchers involved in the development of the oral contraceptive pill, Min Chueh Chang helped to revolutionize the birth control movement. Although best known for his involvement with "the pill," Chang also made a number of discoveries throughout his scientific career involving a range of topics within the field of reproductive biology. He published nearly 350 articles in scientific journals.
William Smellie (1697–1763)
William Smellie helped to incorporate scientific medicine into the process of childbirth in eighteenth century Britain. As a male physician practicing in childbirth and female reproductive health (man-midwife), Smellie developed and taught procedures to treat breech fetuses, which occur when a fetus fails to rotate its head towards the birth canal during delivery. Throughout his career, Smellie compiled a wealth of information about female anatomy in his writings. He modified medical technology such as the obstetrical forceps, an instrument used to maneuver the fetus during childbirth.
Katharine McCormick (1876-1967)
Katharine Dexter McCormick, who contributed the majority of funding for the development of the oral contraceptive pill, was born to Josephine and Wirt Dexter on 27 August 1875 in Dexter, Michigan. After growing up in Chicago, Illinois, she attended the Massachusetts Institute of Technology (MIT), where she graduated in 1904 with a BS in biology. That same year, she married Stanley McCormick, the son of Cyrus McCormick, inventor and manufacturer of the mechanized reaper.
George Richard Tiller (1941-2009)
George Richard Tiller, a doctor who performed abortions in Wichita, Kansas, was shot to death on 31 May 2009 by Scott Roeder. As the director of one of only a small number of clinics in the US that performed legal late-term abortions, Tiller was a target for anti-abortion activists. Though Tiller lived and worked in Kansas, his work agitated anti-abortion groups and fueled the controversy surrounding abortion at a national level. Tiller's life and death fueled the abortion debate in the US.
Charles Benedict Davenport (1866-1944)
Charles Benedict Davenport was an early twentieth-century experimental zoologist. Davenport founded both the Station for Experimental Evolution and the Eugenics Record Office at Cold Spring Harbor in New York. Though he was a talented statistician and skilled scientist, Davenport's scientific achievements are eclipsed by his lasting legacy as the scientific leader of the eugenics movement in the US.
Virginia Apgar (1909–1974)
Virginia Apgar worked as an obstetrical anesthesiologist, administering drugs that reduce women's pain during childbirth, in the US in the mid-twentieth century. In 1953, Apgar created a scoring system using five easily assessable measurements, including heart rate and breathing rate, to evaluate whether or not infants would benefit from medical attention immediately after birth. Apgar's system showed that infants who were previously set aside as too sick to survive, despite low Apgar scores, could recover with immediate medical attention.


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text:
id: 916
title: Technical Issues in Tools (Day 2)
date: 2014-03-23T21:41:11+00:00
author: Aaron Walker
author_url: https://www.linkedin.com/in/aaronwalker
layout: codex_notes_page
guid: http://thetoolsmiths.org/?p=916
permalink: /2014/03/23/technical-issues-in-tools-day-2/
nav_tag: gdc
categories:
  - GDC
---

Below are Aaron's expanded notes from the Day 2 roundtable.

**Dealing Asset Respository Growth**

  * 85% are using Perforce for dealing with content data.
  * Use max revisions to control repository size.
  * Consider using Linux as your Perforce Server platform as it handles scalability concerns better. If using Linux with Windows clients, use case insensitivity from the start to avoid issues.
  * Various user stories were presented on repository growth.
  * Offsite locations, forwarding replicas, edge servers are the new Perforce hotness. Proxies have use but are on the decline.

**Dealing Asset Respository Growth (Gen4)**

  * This question was specifically targetted at dealing with the size of assets that are being generated for Gen4 (PS4/XBone) consoles.
  * If using Unreal, keep package sizes as small as possible.
  * Most people are conditioning as much as possible on the client and not checking in built data.
  * 10% check in built data.
  * 30% are doing full nightly cooks of all assets for validation or to prime a cook cache.
  * Consider pushing cooked data from the client to the cache, but beware of dependency issues!
  * One studio mentioned that it would take them 1 month to clean build the data for their game.
  * Build and keep your dependency tree in memory as much as possible. DB would be an option here.
  * Write dependancy data on first build. Be sure to invalidate it appropriately.

**Build Tools for Data**

  * 10% use 3rd party solution.
  * 80% use a home grown solution.
  * ANT, Grant/Javascript, CruiseControl with MSBuild, Unity, Incredibuild were called out as solutions being used.

**Cross-platform Data**

  * 60% say their data build system support multiple platforms as a core concept.

**Pipeline "Chugging"**

  * How do you deal with the stalls and other implications of gating based on results of CI?
  * 60% or more have someone who wrangles their CIS system.
  * If your CIS system is crunching on data, make that apparent/inspectable by your users.
  * Make public or VERY PUBLIC who is breaking your builds.
  * If you find yourself in situations of repeated breakage, put your senior staff in charge. They can often apply the necessary leverage to communicate the importance of not breaking builds to your staff.
  * Beware of the implications of queuing your submits if you have some kind of automated validation on submit.
  * Very few teams are using a different data version for development than production. Many support single file loading as an iteration tool to mitigate this.
  * Reducing the quality of conditioned data was called out as one way to speed up iterative build times.

**Continuous Deployment**

  * Few do full deployment of tools and game as monolithic installer.
  * TeamCity generates artifacts that are web accessible.
  * Minority of teams have beta and release versions of tools.
  * One team does 2 week iterations and no teams indicated that they are on "Live" tools that have not passed some kind of validation.

**Automated Testing**

  * Outside of core systems there were some questions related to test falures due to changes to requirements that invalidate tests.
  * Test "things that don't change". I read into this as "test things that have stable requirements".
  * Make sure that the people writing the code are also maintaining the tests.
  * Have QA modify test scripts.
  * Are issues with test failure an issue with the developer or somewhere else? Make sure that your devs are running your tests.
  * Some teams do a pre-submit validation where tests are run and reject on failure. Introduces build queueing!
  * One team locked the entire perforce depot on broken build. They said they had 48 devs. A lot of raised eyebrows and questions on this one.
  * Use staged builds in your CI system.
  * Make the team responsible for build stability.
  * Use nightly functionality testing.
  * Block builds when critical path (does game boot?) breaks.
  * How do you deal with non-deterministic systems? Kill non-determinism in your code with fire.
  * Use perforce file locks to indicate code that is under test to inform other users and prevent submit contention.

**Scaling Automated Testing**

  * What do you do when your platform has expensive dev hardware?
  * Use kits on the floor when they are idle.
  * Use PC build to test bulk of changes and test only what is necessary on target hardware.

**Other Topics** – Large Photoshop files. – Forwarding Replica and Edge servers (Perforce) – Compress files on server if you have the horsepower. – Use different (smaller) data formats. – Almost 100% of teams store source PSD files despite large sizes.


The government has a reputation for lagging behind the private sector when it comes to technology use, but at least five e-government projects are on IT's cutting edge, a senior administration official said.
"At the level of spending we do with IT, we need to be on the leading edge,"
Forman told the audience at the luncheon at FOSE 2002 in Washington. "These projects exemplify that leading edge, and with these we are catching up and passing industry in using technology."
Small Business Administration's www.Businesslaw.gov. The site, launched in December, helps small businesses find, understand and comply with federal, state and local laws and regulations.
Defense Department's Common Access Card. The card combines an identification infrastructure with public-key infrastructure and physical access into a single platform for electronic business functions and to improve security and communication.
Interior Department's Recreation One-stop, one of OMB's 24 e-gov initiatives. Interior will build on Recreation.gov to develop a national database of recreational information, provide transactional services and a searchable map.
Transportation Department's Virtual University. The site, which was folded into the Office of Personnel Management's electronic learning e-gov initiative, promotes distance learning and makes taking courses easier and less costly for employees.
Environmental Protection Agency's Natural Language Interface to Web Content project. The project merited a new award for innovation. It lets EPA's chemical emergency preparedness prevention office disseminate real-time Web content to local emergency planning committees and to less equipped groups by standard telephone.
Projects were chosen from 16 initiatives nominated by members of the Quad Council.


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Adamant berserker shield 0 - Items :: Tip.It RuneScape Help :: The Original RuneScape Help Site!
The degraded form of an adamant berserker shield purchased from the Fist of Guthix rewards shop.
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Recharge cost is 10 tokens. Requires level 35 Defence to equip.


text:
The first cryptocurrency to capture the public imagination was Bitcoin, which was launched in 2009 by an individual or group known under the pseudonym, Satoshi Nakamoto. As of February 2019, there were over 17.53 million bitcoins in circulation with a total market value of around $63 billion (although the market price of bitcoin can fluctuate quite a bit). Bitcoin's success has spawned a number of competing cryptocurrencies, known as "altcoins" such as Litecoin, Namecoin and Peercoin, as well as Ethereum, EOS, and Cardano. Today, there are literally thousands of cryptocurrencies in existence, with an aggregate market value of over $120 billion (Bitcoin currently represents more than 50% of the total value).
^ Iansiti, Marco; Lakhani, Karim R. (January 2017). "The Truth About Blockchain". Harvard Business Review. Harvard University. Archived from the original on 18 January 2017. Retrieved 17 January 2017. The technology at the heart of bitcoin and other virtual currencies, blockchain is an open, distributed ledger that can record transactions between two parties efficiently and in a verifiable and permanent way.
I love the fact that we have proponents for trading and not just hodling alone but most confuse buying and holding coins as investment. That's risky because most commentary about future predictions are wrong. Nobody knows for sure the future with bitcoin or the ALTs and speaking about capitulation and a reversal where the bulls take charge completely, you can only be sure when its already happened. A year ago, we thought it was a capitulation when btc dropped from about $20,000 to $6,000 and it was expected to quickly rebound and find a new hight, but unfunatly it didn't happen that way everybody thinks. To do well with cryptos, you need to find a working system to use in expanding that portfolio over and over again until the next resistance which many believe to be in the range of $15,000. I got 3.2 more BTC, 5.7 LTC, 2 ETH and many other unpopular alt coins last month and all are now in trading, and applying a currency prediction tool called ATRS to bypass crypto market risk, I won't divulge into that for now. The software is built and programmed with the ability to identify the rise of any cryptocurrencies when it's high and indicating when to sell out in the crypto market keeping you at a maximized profit payout and also automatically opt out when the prices of any crypto is going low. The real money comes with Research, trading and Patience. I will stop here so I don't bore you guys, but it is sure worth your time. in case you are interested in venturing into investing in Crypto and Digital Currencies, or perhaps you are trading them but you don't understand what you are doing, Hope this advice helps because in the long run what it all comes down to, its just crypto, You and Me hopefully making the right decisions, feel free to get in touch with me, I will be sure to guide and assist you with any information you may need to invest in these new and unpopular crypto and digital currencies that are making waves at the moment. jaxonelliot001@gmailcom
J. P. Morgan Chase is developing JPM Coin on a permissioned-variant of Ethereum blockchain dubbed "Quorum".[52] It's designed to toe the line between private and public in the realm of shuffling derivatives and payments. The idea is to satisfy regulators who need seamless access to financial goings-on, while protecting the privacy of parties that don't wish to reveal their identities nor the details of their transactions to the general public.[53]
In March 2013 the blockchain temporarily split into two independent chains with different rules due to a bug in version 0.8 of the bitcoin software. The two blockchains operated simultaneously for six hours, each with its own version of the transaction history from the moment of the split. Normal operation was restored when the majority of the network downgraded to version 0.7 of the bitcoin software, selecting the backward compatible version of the blockchain. As a result, this blockchain became the longest chain and could be accepted by all participants, regardless of their bitcoin software version.[42] During the split, the Mt. Gox exchange briefly halted bitcoin deposits and the price dropped by 23% to $37[42][43] before recovering to previous level of approximately $48 in the following hours.[44] The US Financial Crimes Enforcement Network (FinCEN) established regulatory guidelines for "decentralized virtual currencies" such as bitcoin, classifying American bitcoin miners who sell their generated bitcoins as Money Service Businesses (MSBs), that are subject to registration or other legal obligations.[45][46][47] In April, exchanges BitInstant and Mt. Gox experienced processing delays due to insufficient capacity[48] resulting in the bitcoin price dropping from $266 to $76 before returning to $160 within six hours.[49] The bitcoin price rose to $259 on 10 April, but then crashed by 83% to $45 over the next three days.[40] On 15 May 2013, US authorities seized accounts associated with Mt. Gox after discovering it had not registered as a money transmitter with FinCEN in the US.[50][51] On 23 June 2013, the US Drug Enforcement Administration listed ₿11.02 as a seized asset in a United States Department of Justice seizure notice pursuant to 21 U.S.C. § 881.[52][better source needed] This marked the first time a government agency had seized bitcoin.[53] The FBI seized about ₿30,000[54] in October 2013 from the dark web website Silk Road during the arrest of Ross William Ulbricht.[55][56][57] These bitcoins were sold at blind auction by the United States Marshals Service to venture capital investor Tim Draper.[54] Bitcoin's price rose to $755 on 19 November and crashed by 50% to $378 the same day. On 30 November 2013 the price reached $1,163 before starting a long-term crash, declining by 87% to $152 in January 2015.[40] On 5 December 2013, the People's Bank of China prohibited Chinese financial institutions from using bitcoins.[58] After the announcement, the value of bitcoins dropped,[59] and Baidu no longer accepted bitcoins for certain services.[60] Buying real-world goods with any virtual currency had been illegal in China since at least 2009.[61]
An official investigation into bitcoin traders was reported in May 2018.[186] The U.S. Justice Department launched an investigation into possible price manipulation, including the techniques of spoofing and wash trades.[187][188][189] Traders in the U.S., the U.K, South Korea, and possibly other countries are being investigated.[186] Brett Redfearn, head of the U.S. Securities and Exchange Commission's Division of Trading and Markets, had identified several manipulation techniques of concern in March 2018.
It has come to the notice of authorities that many unregulated companies are using clone websites to target citizens and hence it has issued a warning to all traders not to deal with any unregulated companies and not to be lured by their false propaganda of unrealistic returns on investments, and not to fall in their trap. Their advertisements can be mouthwatering, but at the end of the day they will run off with your capital too. Thanks to recovery company they helped me recovery most of my lost funds, you can contact bitcoinrecoveryteam{@}yandex,ru and share the testimony they shouldn't rip
After much debate, the Ethereum community voted and decided to retrieve the stolen funds by executing what's known as a hard fork or a change in code. The hard fork moved the stolen funds to a new smart contract designed to let the original owners withdraw their tokens. But this is where things get complicated. The implications of this decision are controversial and the topic of intense debate.
Ethereum can also be used to build Decentralized Autonomous Organizations (DAO). A DAO is fully autonomous, decentralized organization with no single leader. DAO's are run by programming code, on a collection of smart contracts written on the Ethereum blockchain. The code is designed to replace the rules and structure of a traditional organization, eliminating the need for people and centralized control. A DAO is owned by everyone who purchases tokens, but instead of each token equating to equity shares & ownership, tokens act as contributions that give people voting rights.
On 29 Novemvber 2017, South Korean Prime Minister Lee Nak-yeon raised concerns that cryptocurrencies were corrupting the youth of South Korea, remarking "There are cases in which young Koreans including students are jumping in to make quick money and virtual currencies are used in illegal activities like drug dealing or multi-level marketing for frauds".[235]
2) Pseudonymous: Neither transactions nor accounts are connected to real-world identities. You receive Bitcoins on so-called addresses, which are randomly seeming chains of around 30 characters. While it is usually possible to analyze the transaction flow, it is not necessarily possible to connect the real world identity of users with those addresses.
Full clients verify transactions directly by downloading a full copy of the blockchain (over 150 GB As of January 2018).[100] They are the most secure and reliable way of using the network, as trust in external parties is not required. Full clients check the validity of mined blocks, preventing them from transacting on a chain that breaks or alters network rules.[7]:ch. 1 Because of its size and complexity, downloading and verifying the entire blockchain is not suitable for all computing devices.
Bitcoin mining saps energy, costly, uses more power and also the reward delays. For mining, run software, get your wallet ready and be the first to solve a cryptographic problem and you get your reward after the new blocks have been added to the blockchain.Mining is said to be successful when all the transactions are recorded in the blockchain and the new blocks are added to the blockchain.
Ethereum's smart contracts are based on different computer languages, which developers use to program their own functionalities. Smart contracts are high-level programming abstractions that are compiled down to EVM bytecode and deployed to the Ethereum blockchain for execution. They can be written in Solidity (a language library with similarities to C and JavaScript), Serpent (similar to Python, but deprecated), LLL (a low-level Lisp-like language), and Mutan (Go-based, but deprecated). There is also a research-oriented language under development called Vyper (a strongly-typed Python-derived decidable language).
The first wallet program, simply named Bitcoin, and sometimes referred to as the Satoshi client, was released in 2009 by Satoshi Nakamoto as open-source software.[16] In version 0.5 the client moved from the wxWidgets user interface toolkit to Qt, and the whole bundle was referred to as Bitcoin-Qt.[112] After the release of version 0.9, the software bundle was renamed Bitcoin Core to distinguish itself from the underlying network.[113][114]
Hello, Traders! Monfex is at your service. ETH is located near the global support line and is approaching to the resistance level inside the downward channel. RSI is overbought. While the coin is forming a shape, you need to follow the updates under this chart to know what you need to do. The position is neutral. The target for the breakout of the resistance...
Decentralized cryptocurrency is produced by the entire cryptocurrency system collectively, at a rate which is defined when the system is created and which is publicly known. In centralized banking and economic systems such as the Federal Reserve System, corporate boards or governments control the supply of currency by printing units of fiat money or demanding additions to digital banking ledgers. In case of decentralized cryptocurrency, companies or governments cannot produce new units, and have not so far provided backing for other firms, banks or corporate entities which hold asset value measured in it. The underlying technical system upon which decentralized cryptocurrencies are based was created by the group or individual known as Satoshi Nakamoto.[23]
Litecoin was one of the first cryptocurrencies after Bitcoin and tagged as the silver to the digital gold bitcoin. Faster than bitcoin, with a larger amount of token and a new mining algorithm, Litecoin was a real innovation, perfectly tailored to be the smaller brother of bitcoin. "It facilitated the emerge of several other cryptocurrencies which used its codebase but made it, even more, lighter". Examples are Dogecoin or Feathercoin.
It takes a (global) village to raise a blockchain. The live network and the community of open source developers contribute significantly to this effort. They continuously refine and harden the Ethereum platform, helping it get faster at responding to industry demands for the value propositions it offers. These investments of time and resources speak to their faith in Ethereum governance and the value that businesses and developers see in its capabilities. – Joseph Lubin, CEO of Consensys
In Ethereum all smart contracts are stored publicly on every node of the blockchain, which has costs.[56] Being a blockchain means it is secure by design and is an example of a distributed computing system with high Byzantine fault tolerance. The downside is that performance issues arise in that every node is calculating all the smart contracts in real time, resulting in lower speeds.[56] As of January 2016, the Ethereum protocol could process about 25 transactions per second.[56] In comparison, the Visa payment platform processes 45,000 payments per second leading some to question the scalability of Ethereum.[57] On 19 December 2016, Ethereum exceeded one million transactions in a single day for the first time.[58]
Network nodes can validate transactions, add them to their copy of the ledger, and then broadcast these ledger additions to other nodes. To achieve independent verification of the chain of ownership each network node stores its own copy of the blockchain.[80] About every 10 minutes, a new group of accepted transactions, called a block, is created, added to the blockchain, and quickly published to all nodes, without requiring central oversight. This allows bitcoin software to determine when a particular bitcoin was spent, which is needed to prevent double-spending. A conventional ledger records the transfers of actual bills or promissory notes that exist apart from it, but the blockchain is the only place that bitcoins can be said to exist in the form of unspent outputs of transactions.[7]:ch. 5
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LANSING, Mich. – As part of National Public Health Week, 15 individuals and organizations will be presented with the 2019 Hometown Health Hero and Jean Chabut Health Policy Champion awards for their contributions to protecting and improving the health of Michigan residents on April 10 at the state Capitol.
The Michigan Public Health Week Partnership is hosting the event to honor those who are helping Michigan achieve its goal of "Creating the Healthiest Nation: For science. For action. For health." This year's awards focus on healthy communities, violence prevention, rural health, technology and public health and climate change.
To achieve the Project Public Health Ready (PPHR) national recognition, the Oakland County Health Division had to demonstrate preparedness and response capability by meeting a comprehensive set of nationally-recognized standards. PPHR standards focus on three main goals: all-hazards planning, workforce development and demonstrating readiness through exercises and real events aligned with federal government requirements and national best practices.
In 2018, this group of legislators worked together to pass a bi-partisan bill package that will decrease stigma, increase access to care, and bring the public health code in line with current science for HIV. HB 6016-HB 6023 will modernize HIV reporting and testing requirements. The key points of the bills include adding a mandatory third trimester test for pregnant women to prevent perinatal transmission of HIV, syphilis and hepatitis B and modifications to Michigan's HIV disclosure laws.
When shelter agencies in Ypsilanti and Ann Arbor need help with youth health services, Bennett is the first person they turn to for assistance. A nurse practitioner at the Corner Health Center, she created the F-Sharp program to provide health assessments to teens and young adults experiencing homelessness. The program also enrolls them with a medical provider so they can manage their own care no matter where they are living at the time. In FY 2018, more than 200 youths were seen with 65 percent of those referred to the Corner showing up for their appointments.
Whenever there's a need within his community, Benning, general manager/CEO of Mass Transportation Authority (MTA), immediately thinks about how transportation can play a part in serving that need. Benning created the Rides to Groceries program when Flint residents no longer had access to nutritious foods due to the closure of many local grocery stores. During the Flint water crisis, Benning directed the MTA to transport workers and supplies into neighborhoods and turned MTA locations into water storage and distribution centers. Following the success of the program, he created Rides for Wellness and Rides for Veterans to help residents get to and from medical appointments, pharmacies and grocery stores and VA hospitals in Michigan.
Brott has found innovative ways to connect service providers with the residents in St. Joseph County in need of their services. She was integral to a website redesign that integrated a community calendar and the development of a comprehensive resource guide for service providers so appropriate referrals could be made beyond their own agencies. Annually, she has been instrumental in coordinating the annual Project Connect/Veterans Stand Down event; putting residents in touch with county services, health screenings, vaccinations and food assistance.
Ele's Place has been a longtime haven for grieving families in Greater Lansing to seek programming and support under one roof. Through funding from Delta Dental, Ele's Place was able to expand their services to 34 school districts throughout Michigan. The program supports grieving students, making sure they have on-site, accessible support that allows them to grieve and process loss while not disrupting their normal student activities, routines and lifestyle. School-based groups of students meet for eight weeks during one class period. A school counselor and an Ele's Pace staff member coordinate the grief support groups, assuring a safe space for students to talk openly, sometimes for the first time, about their losses. The program has fostered significant improvement of mental and emotional health as well as academic performance for participants.
4-18. Many of these students did not have access to healthcare as school nurses had been eliminated from all area school budgets. Soon after the program began, school nurses were able to keep students in school learning, instead of sending them home; decreasing chronic student absenteeism by 32 percent. In addition, nurses provide safety education for any procedures performed by nonmedical school staff including tube feeding administration, urinary catheterization, insulin pumps and even anticonvulsants administration.
Launched by Beaumont Health, Healthy Dearborn is a partnership between Beaumont, City of Dearborn, Dearborn Public Schools and more than 400 community members working together to create a culture of health by ensuring access to healthy eating and active living opportunities. The coalition has numerous accomplishments, including 5,200 residents participating in free community-based health screenings; developing a seed library to encourage community gardening; launching a bike share program; enhancing Dearborn's bike/walk-ability with extensions of rails and paid paths; and providing 1,300 residents with community education programs focusing on diabetes prevention and management, healthy nutrition and healthy cooking. There have also been more than 200,000 after school fitness sessions since 2016.
When Kermeen clocks out of work, she does not go home or run errands, instead she visits migrant communities in Ottawa County to provide sexual health services and education to break down barriers to STD testing and treatment. During the last two years, Kermeen has worked with public health agencies, private farm owners and growers and a multicounty migrant resource council to identify and treat communicable diseases within the camps; primarily in men under the age of 25. Her work to slow or stop the spread of infections, such as chlamydia, has positively impacted migrant farmworkers and the community at large. She also connects with local food pantries to seek donated food, ensuring the workers have access to fresh fruits and vegetables, clothing, toothbrushes and other necessities.
Pavona suffered a devasting loss when his son died from an opioid overdose. A retired hospital employee, Pavona had a special level of experience working with systems to create change. He started the second Families Against Narcotics (FAN) Chapter in Ingham County and has driven across the state to help start numerous other chapters across Michigan. FAN brings together local drug court judges, law enforcement and parents who have lost their children to addiction and overdose. Participants work together to raise awareness about the dangers of narcotics as well as support families struggling with the impact of narcotic addiction. The program has increased the number of individuals trained to administer Naloxone, expanded peer recovery support across Michigan and supported people in recovery and families that are court-involved.


i'm so glad you like everything jodi!!
and i'm also very very happy to see that the hoops are still standing for the world cup! haha, you have no idea the headache i went through trying to make them all tiny.. which is why they're far from perfect. anyways, i had to make tiny armatures out of foil so that they would stand, so if they happen to tip over, you *should* be able to push them back into place..
when you kept mentioning quidditch, i HAD to make something cool! luckily i was able to brainstorm this idea while in class.. who needs to listen to a teacher blab about history anyways??
thanks again for being my partner!! and i wanna thank implacey again for organizing this amazing swap!
i'm a cheater, that's how! i tried to just do the regular old stencil with freezer paper.. spent like 2 hrs cutting out all the letters (on the back is a quote from the book.. why are you worried about u - know - who) and when i started to iron on the fabric, it turned it all sorts of purple and i almost had a heart attack.. then i got over it and just stencilled.. but either because of the fabric or the zipper on the other side making it hard to iron on.. my paint bled. alot. i cried.
All of that stuff is fabulous! So there is another Gryffindor besides me!
Well I haven't heard from my partner, girlwonder, since.. way before christmas. I know she recieved her stuff (thank you good ol' d/c number). SOOO... I figured I'd post what I sent anyway!
Her fav house was slytherin.. so I based everything on that!
i have a total love for all harry-potter related scarves, especially since my wonderful partner hgflower sent me my AWESOME gryffindor scarf, which even as we speak is keeping me from turning into an icicle!!
I love the pin, so pretty! Very smart way to hold your scarf.
daiconharuko - that shirt is great! the snake is cute - love it all.
Expecto Patronum..... Caught the snitch!
Ollivander's Sattelite Shop in Ontario?