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The A.I. Age
Microsoft invests in Adaptive Biotechnologies to develop blood test to detect diseases
Originally published January 4, 2018 at 2:53 pm Updated January 4, 2018 at 10:20 pm
Microsoft's partnership with Seattle-based Adaptive Biotechnologies will focus on mapping and understanding people's immune-system responses so that illnesses can be found quickly.
Rachel Lerman
Seattle Times business reporter
Microsoft is delving deeper into health-care technology with a commitment to try to develop a blood test that detects diseases in their earliest stage.
The Redmond company announced a partnership with Seattle-based Adaptive Biotechnologies on Thursday, one that will focus on mapping and understanding people's immune-system responses so that illnesses can be found quickly.
As part of the deal, Microsoft has made a significant investment in Adaptive. Neither company would confirm the amount, but they said the project would cost in the low hundreds of millions of dollars and Microsoft would contribute a "substantial portion."
The investment is part of Microsoft's Healthcare NExT initiative, which brings artificial intelligence power to health issues.
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Adaptive, which was formed in 2009 with technology from the Fred Hutchinson Cancer Research Center, works to understand the immune system's response to various diseases. The company is developing a map of sorts to track immune responses.
Microsoft's machine learning and AI technology will be used to help create the map and "read" the code that the immune system transmits, said Adaptive CEO Chad Robins. That includes being able to tell which diseases the immune system has fought before and what it is currently fighting.
Armed with that information, Adaptive plans to develop blood tests that alert doctors when people are fighting specific diseases. Eventually, Microsoft and Adaptive want to create a universal blood test that detects any disease a body might be fighting.
That ultimate test is probably 10 years away, Robins said, but intermediate tests are much closer.
Many diseases are diagnosed by tracking symptoms, he said, but the immune system always knows precisely what it's fighting.
"We want to let the immune system tell the doctor what's wrong with you," Robins said.
Microsoft's technology will consider the huge amounts of data Adaptive collects with immune sequencing.
"The remarkable thing about your immune system is it's an incredibly effective machine-learning system in its own right, "said Peter Lee, Microsoft corporate vice president of AI and research.
Microsoft employees will work closely with Adaptive, and the company plans to hire more people for the team, Lee said.
Adaptive has been a growing force in the Seattle biotech scene for years, and netted $195 million from investors in 2015. The company has close ties to Fred Hutch, where Microsoft CEO Satya Nadella serves as a board trustee.
Rachel Lerman: rlerman@seattletimes.com; on Twitter @rachelerman.

redpajama_set_name: RedPajamaCommonCrawl


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Two killed, one injured in Riverside car accident on 91 FWY
According to KTLA, two people were killed and another was injured in a fatal car accident caused by a drunk driver on the 91 Freeway in Riverside on Friday, August 10, 2018.
The fatal car accident was reported around 1:47 a.m., when the drunk driver was reported to have been driving on the wrong side of the road – traveling eastbound in the westbound lanes.
As a result, the drunk driver collided head-on with another vehicle near the Central Avenue exit.
The driver and the passenger in the car that was struck by the wrong-way driver, both identified as females, died at the scene of the car accident.
Another passenger, identified as a man, sustained major injuries and was transported to a nearby hospital.
The drunk driver was found at the scene of the car accident and was arrested on suspicion of DUI.
The fatal car accident remains under investigation.
Our team at West Coast Trial Lawyers sends our deepest condolences to the family and loved ones of the two victims killed in the car accident. We also wish the other victim injured a speedy recovery.
Car accidents can result in serious injuries or fatalities for those involved. If you or a loved one has been injured due to the fault of a negligent driver, you need to seek help from a car accident lawyer as soon as possible.
At West Coast Trial Lawyers, our team of car accident attorneys have gotten outstanding results for our clients. We understand how stressful the outcome can be when it comes to dealing with a car accident, and it is important to know that you can get help from a legal team you can trust.
Our team is available 24/7 for a free, no-obligation consultation. Feel free to call us any time at (888) 888-9285. Our personal injury lawyers are ready to help.


I can't find an attribution for this quote, so if anyone knows where it originated, please pass it along to me to include, but it resonates with me deeper than the usual pithy self-help meme.
Living without expectations, as other quotes over the years have suggested, certainly makes for what they call a happier life. I struggle, however, with the advice that we should just not expect anything from ourselves or anyone else.
Some expectations are unreasonable. You meet someone for the first time, and you think they will be your world. That's probably unreasonable. You should have expectations for their behavior — that they will treat you with respect and kindness, that they will not be a serial killer— but you probably shouldn't make expectations regarding their feelings for you or their commitment to you on first meeting. We don't live in a novel or romantic comedy. However, if they do turn out the be a serial killer, you can't blame yourself for believing that they wouldn't be one. That was not a likely scenario.
You start a new job, and you expect it to be the best job you've ever had. If you didn't have this attitude about your new job, why would you take it? In this case, your expectations are that your feelings will be positive. That's not an unreasonable expectation. The standard reasonable expectation that your co-workers will treat you with respect is also part of that expectation. When the job turns out to be horrible because your manager is a sociopath, you can't blame yourself for having had those positive expectations. If you took the job knowing that you didn't have the skills to do it, however, its failure would hinge to a certain degree on your unreasonable expectation of being able to accomplish something you knew you couldn't.
Expectations are a minefield of feelings, dreams, and interactions. Sometimes, it's only in hindsight that we realize our expectations were unreasonable. We just didn't see it.
Other expectations are carefully constructed over years of iterative experiences that grow like a drip castle in the sand. We build a foundation for them, whether solid or otherwise, on interactions and encounters. These are the hardest expectations to fight. A marriage isn't built in a day. It's (usually) built over years of experiences that create a baseline of expectations of each partner's behaviors. For instance, when two partners have been together for five years with no sign of gender confusion, there is a baseline for behavior that does not include one of the partners being transgender. If one of the partners is in fact transgender, the drip castle feels like a lie to the cisgender partner.
This is not in and of itself a death knell for the relationship. It requires a massive reorienting of expectations, however. That said, to have expected one spouse to live without any expectations as to the gender identity of the other spouse for the first five years on the possible fact that said spouse is transgender would not have been good advice. The simplistic quote about not letting expectations dictate your happiness fails when the complexity of real life, fractal in its threads of experience, comes into play.
I might sound like I'm trying to dismantle the initial quote, but I'm actually not. I read that quote on someone's Instagram feed, and it resonated with me. There are times when I have let my own unreasonable expectations dictate my feelings and experiences. I have expected someone to feel a certain way because I only looked a their behavior in snippets instead of its totality. I have expected parts of my life to change with no change in behavior from me when there were no objective signs that any such change was out there. It's not intellectual laziness. It's bred in the hope that what we so desperately want will manifest. But that is not the reality of manifestation.
Manifesting is short for doing a lot of hard work, self-examination, and orienting ourselves in a direction. Manifestation isn't actually manifesting. You can manifest a positive attitude and a plan, but you can't manifest wealth, love, or success directly. You manifest the attitude required to build those things for yourself. That's an important distinction.
Back to expectations. Not all of them are bad. They help us approach experiences with positivity and openness. They provide a social baseline that can shortcut judgments— in either direction depending on how you orient them (i.e., positive or negative expectations). But, what we need to be careful about are those expectations that make a leap from the normal baseline to a result derived on the desire for behavior from others that is outside the baseline norms of everyday life.
All of these (love, skills, success) require work and effort to get the result, so the expectations that they are to be approached as an immediate boon are not reasonable.
Today's photograph is from a new project that I've started. You an find the link to it on my site – I'm trying out the idea of writing a haiku a day and scrapbooking it. Journaling done minimal and slightly visual. The ideas are short, the presentation is somewhat precious, but the result is not perfect. Maybe in a year, I will look back and see an evolution in my thinking. Link to the gallery here or check out my daily posting on my Instagram (@alialuria #scrapbookinhaiku).


Detached luxury villa model Lucia, Campoamor beach,Orihuela Costa.
Villa Model 'Lucia' Campoamor beach, Orihuela Costa.
Fantastic luxury villa in the beach area of Campoamor in Orihuela Costa, built with high quality materials and modern avant-garde design, focused on receiving the maximum natural light with large windows and spacious units.
There is the possibility to make changes to the design if you order prior to construction.
The 'Lucia' model has three bedrooms, all with their own en-suite.There is a further bathroom downstairs, large living room with open kitchen, and gallery/laundry room. This model stands on a plot of approx. 500m2 with private pool and parking area.


Looking for a better work life balance ...?
This Therapy company in Guernsey is looking for an enthusiastic Band 6 Physiotherapist to join their dynamic Paediatric team on a 6-month contract from March 2019.
They believe in intensive, patient centred rehabilitation, aiming to achieve the best possible outcomes facilitated by skilled and motivated physiotherapists and assistants. Offering clinical supervision, peer support and commitment to CPD.
The successful candidate will have a minimum of 2 years paediatric experience and a passion to provide high-quality care.
Our client is a private physiotherapy practice contracted by the States of Guernsey to provide physiotherapy services within secondary health care. We also offer services to private clients.
Guernsey is part of the Channel Islands, offering a wealth of outdoor activities, good connections to UK and low taxation. If you are looking to escape the long commutes and enjoy an idyllic summer on a beautiful island, we are the firm for you.
If you wish to be considered for this Physiotherapist role please click "Apply" today! You will receive an email which will give you information on how to get a detailed job description and the full application pack.


text:
from setuptools import setup

setup(
    name='vs_auditor',
    version='0.1',
    description='ValueStore backend for OpenStack Swift Auditor',
    license='Apache License (2.0)',
    packages=['vs_auditor'],
    classifiers=[
        'License :: OSI Approved :: Apache Software License',
        'Operating System :: POSIX :: Linux',
        'Programming Language :: Python :: 2.6',
        'Environment :: No Input/Output (Daemon)'],
    install_requires=['swift', ],
    entry_points={
        'paste.app_factory': [
            'vs_object=vs_auditor.vs_server:app_factory'],
    },
)

redpajama_set_name: RedPajamaGithub