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Predictions for the 91st Academy Awards
by Cineccentric Critics
Best Sound Editing:
One of the broadest categories of the ceremony this year, the Academy Award for Best Sound Editing has thrown attention towards mighty blockbuster spectacles, goosebump-inducing concerts, insular intergalactic travel and even tension-fueled horror. Sergio Diaz's work on Roma is the most subtle of the nominations, providing a layered and rich soundscape to accompany Cuarón's vision of a living, breathing Mexico City. John Warhurst's work on Bohemian Rhapsody notably deserves credit no matter what your opinions on the film are. The massive undertaking of combining Freddy Mercury's iconic vocals with Rami Malek's performance during the musical scenes is nothing short of gigantic, and it's pretty much agreed it's the one area in which the film truly excels. Ai-Ling Lee backed up the technical powerhouse that is Damien Chazelle's First Man with a terrifyingly bleak and intense look at a lunar soundscape. The opening alone as Ryan Gosling's Neil Armstrong is bounced off of the atmosphere in the X-15 is enough to work as an audio drama for the ages. Benjamin A. Burtt and Steve Boeddekker managed to match Black Panther's spectacle by incorporating the sounds of Wakanda fluidly into the Marvel Cinematic Universe, with particular detail going into the reverberation of the vibranium Black Panther suit itself being icing on the cake. Then a film that utilizes sound as a weapon needed some marvelous work in the editing department, and Ethan Van der Ryn and Erik Aadahl were able to create scares from a pin drop within A Quiet Place. An extremely varied category and one filled with brilliant, often-unspoken-of work from editors who are pivotal in providing a true escapist fantasy.
Prediction: First Man
Best Sound Mixing:
The sound mixing category this year has a generally nice blend of films that recognize its importance, from the terrifying claustrophobia of space in First Man to the euphoric high of a rock concert in A Star is Born (and Bohemian Rhapsody) to the comic book action of Black Panther. But no film is more deserving of the award than the sound mixing crew of Roma, who manage to construct an immersively overwhelming and intimately psychological soundscapes.
While the surround sound effect of Roma is lost to varying degrees on audiences watching through Netflix, the film's blend of the natural sounds of its protagonist's world are precisely engineered to come from where she experiences them, and more importantly how she experiences them. The film's handful of horrifying scenes of violence and stunningly cinematic instances of catharsis would not be half as beautiful without such masterful sound mixing, and choosing any other film to win in its place would be an unforgivable disgrace.
Prediction: A Star is Born
Best Visual Effects:
Over the past few years we seem to have reached an impasse in regard to visual effects. Whereas before the advancements year after year were what made all the difference, technology has progressed so much that now we live in a world where the small details are the finer things. First Man's nomination comes from a place of begrudging reality; its moments of spectacle are, just as in life, sparse and minimal. In an environment overpopulated by effects, a film like this is designed to remind us of the impact minimalism can have. Of course, then there's Industrial Light & Magic with three nominations in the category this year to show off just how talented they are. Their work in Ready Player One is the epitome of popcorn insanity, and they did the work of ten studios by just sheer amount of recognizable assets on screen. Avengers: Infinity War goes along a similar route, but thanks to particularly strong motion capture performances from the likes of Josh Brolin as Thanos, the extra dimension to the computer-generated characters may just be able to push them towards the win against the competition. This same level of quality is laced across their work in Solo: A Star Wars Story, combining such nostalgic iconography with new worlds and characters to craft another solid entry from a galaxy far, far away. The dark horse in the category is definitely Christopher Robin however. Initially mocked upon the reveal of its 'realistic' depictions of Winnie the Pooh characters, the context of the film strengthens the aesthetic of the wear-and-tear bear from the hundred acre wood and are as charming as the film they reside.
Prediction: Avengers: Infinity War
Tags2018 Sundance Film Festival • 91st Academy Awards • A Night at the Garden • A Quiet Place • A Star is Born • Adam Driver • Adam McKay • Ai-Ling Lee • Alexandre Desplat • Alfonso Cuaron • America • Amy Adams • Animal Behaviour • Annihilation • At Eternity's Gate • Avengers: Infinity War • Bad Times at the El Royale • Bao • Barry Lyndon • Benjamin A. Burtt • Bing Liu • Black Panther • Black Sheep BlacKkKlansman • Bohemian Rhapsody • Border • Bradley Cooper • Bridesmaids • Bryan Singer • Burning • Caleb Deschanel • Call Me By Your Name • Can You Ever Forgive Me • Capernaum • Christian Bale • Christopher Robin • Cold War • Cornelius Walker • Cynthia Erivo • D. W. Griffith • Damien Chazelle • Daniel Kaluuya • Detainment • Do the Right Thing • Domee Shi • Drew Goddard • Eighth Grade • Emma Stone • Emmanuel Lubezki • End Game • Eric Roth • Erik Aadahl • Ethan Van der Ryn • Fauve • First Man • First Reformed • Florian Henckel von Donnersmark • Forrest Gump • Free Solo • Germany • Glenn Close • Gravity • Green Book • Greg Cannom • Guillermo Del Toro • Guy Nattiv • Hale County This Morning This Evening • Hereditary • Hirokazu Kore-eda • Ida • If Beale Street Could Talk • Incredibles 2 • Isle of Dogs • Japan • Jeff Whitty • Jeffrey Friedman • Jeremy Comte • John Warhurst • Josh Brolin • Justin Hurwitz • Kate Biscoe • Kendrick Lamar • La La Land • Lady Gaga • Late Afternoon • Lawrence of Arabia • Lebanon • Lee Chang-dong • Lifeboat • Louise Bagnall • Ludwig Gorasson • Lukasz Zal • Mahershala Ali • Marc Shaiman • Marguerite • Marianne Farley • Marina de Tavira • Marshall Curry • Mary Poppins Returns • Mary Queen of Scots • Matthew Libatique • Melissa McCarthy • Mexico • Minding the Gap • Mirai • Moonlight • Mother 2017 short film • Nadine Labaki • Never Look Away • Nicholas Britell • Nicholas Hoult • Nicole Holofcener • No Country For Old Men • Of Fathers and Sons • Olivia Colman • One Small Step • Patricia Dehaney • Paweł Pawlikowski • Period. End of Sentence • Peter Farrelly • Poland • Rachel Weisz • Ralph Breaks the Internet: Wreck-it Ralph 2 • Rami Malek • Rayka Zehtabchi • RBG • Ready Player One • Regina King • Richard E. Grant • Rob Epstein • Robbie Ryan • Rodrigo Sorogoyen • Roma • Ryan Gosling • Sam Elliott • Sam Rockwell • Sergio Diaz • Shaun the Sheep • Shoplifters • Skin • Skye Fitzgerald • Solo: A Star Wars Story • Sorry to Bother You • Spider-Man: Into the Spider-Verse • Spike Lee • Stanley Kubrick • Steve Doeddekker • Terence Blanchard • The Ballad of Buster Scruggs • The Coen Brothers • The Constant Gardener • The Favourite • The Grand Budapest Hotel • The Shape of Water • The Way West • The Wife • Three Billboards Outside Ebbing Missouri • Toni Collette • Trevor Jimenez • Vice • Viggo Mortensen • Vincent Lambe • Weekends • Wes Anderson • Widows • Willem Dafoe • Won't You Be My Neighbor? • Y Tu Mamá También • Yalitza Aparicio • Yorgos Lanthimos • You Were Never Really Here
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America Ferrera and Eva Longoria Poke Fun at the Golden Globes
Naeisha Rose
On Sunday night, Jan. 10th, the Golden Globes was hosted by the ever so wry Ricky Gervais on NBC. Throughout the night, he made fun of celebrities, the Hollywood Foreign Press and of course, Donald Trump.
Eva Longoria and America Ferrera aren't just beautiful talented actresses, they are also two people who your future president, Donald Trump, can't wait to deport! Please welcome, Eva Longoria and America Ferrera," said Gervais.
The lack of Latinas represented at the Golden Globes couldn't be more apparent either, as Longoria and Ferrera made fun of how they get mistaken for other Latinas whom they barely resemble.
Hi, I'm Eva Longoria, not Eva Mendes," said Longoria. "I'm America Ferrera, not Gina Rodriguez," said Ferrera. "And neither one of us are Rosario Dawson," said Longoria." Well said, Salma," said Ferrera. "Thank you, Charo," said Longoria.
This was also in response to Ferrera being announced last month by the Golden Globes on Twitter as a Best Actress nominee for a Television Series – Comedy or Musical. That nomination was meant for Gina Rodriguez (the only Latina nominated at the Globes), for her show, Jane the Virgin. Ferrera's show, Superstore, didn't preview until late Nov. of last year.
Unfortunately for Rodriguez, she lost to Rachel Bloom of the freshman show, My Crazy Ex-Girlfriend, which is also on the CW network.
The men, however, fared much better at the Golden Globes. Gael Garcia Bernal took home a surprise win as Best Actor in a Television Series – Comedy or Musical for Amazon's Mozart in the Jungle, beating out favorite Jeffrey Tambor who stars in Transparent (also on Amazon), and Aziz Ansari for Master of None (Netflix).
After co-starring in that little movie that could, you know, Star Wars: The Force Awakens, Oscar Isaac continued to strike gold by winning Best Actor in a Miniseries or Motion Picture for Television, in Show Me a Hero (HBO).
The biggest winner of the night was Director and Producer Alejandro G. Inarritu for The Revenant. The film won for Best Picture – Drama and he won for Best Director. This brings Inarritu closer to a possible back-to-back Oscar win.
Despite only one Latina being nominated this year, there are currently three new shows produced and starring Latinas (Superstore, Shades of Blue and Telenovela). If these shows find success and make it into the next year, Rodriguez won't be the only Latina up for a potential nomination and Ferrera being nominated won't be a case of mistaken identity.
Subscribe to our weekly e-Newsletter for the latest news, trends & events: click here, it's quick & easy: http://bit.ly/1BcjOjX
Naeisha Rose is a freelance multimedia journalist living in Queens, New York. She is also a recent graduate of the CUNY Graduate School of Journalism, where she specialized in Arts & Culture reporting and Broadcast. You can follow her on Twitter: @NKRose3.
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As you all (should) know, I support two charities in the fight against Breast Cancer. One, that I just wrote about, is Stand Up 2 Cancer for their pure research. The other is the American Cancer Society. They do research as well, but they are also big on supporting cancer patients individually.
How do they do that? They put on the Look Good, Feel Better classes, which are so important to those of us who are doing chemo for the first time. They provide money that will go towards a wig reimbursement. They provide gas money for rides to doctor's offices, and they have classes for cancer patients on the subject of nutrition, emotional health, and so much more. I have called them with questions myself, and every time have gotten a live person to answer my question, with no hold time.
And a kind live person, one who, if they didn't know the answer, found out rather than giving you the runaround.
They also provide information and statistics that I have used hundreds of times on this blog and for supporting research. Each spring, during chemo, I have received daffodils in my infusion center to brighten my day. They put on the famous Relay for Life which goes directly to support people with cancer. At some point on my bucket list is a goal to sponsor a "But Doctor I Hate Pink" Relay for Life team. Back in the early, frightening days of a new diagnosis, the American Cancer Society was the group that provided me with the most help and information, and I will never forget it.
The ACS catch phrase is "more birthdays" and they work on that with ongoing research, but what they also do is make the birthdays you have left enjoyable, managable ones, by supporting you and educating you and actually helping you. A big plus - they are not focused on breast cancer alone, or "awareness." They will help my uncle with Prostate Cancer, my Aunt with Lung Cancer, and they surely have helped somebody in your family and if they haven't, well, you are pretty lucky.
Of all the charities out there, this is the only one I have personally benefited from. You can see how I feel about ACS in former posts about them here and here and here. So, while I have just asked you to donate to Stand Up 2 Cancer, I also would like you to consider donating to the ACS.
The world does need more birthdays.
This post is sponsored by the ACS, but don't think that I don't mean what I say.
<3 ACS - as I'm currently wearing my purple survivor shirt from this year's Relay for Life in May 2012.
I've looked on the ACS website but can't find where they help with gas to doctor visits or infusion visits. Can u help?
It will lead you to supportive programs in your area. You can also call them up and they will help you. You have to drive a certain distance per year to get the gas card but as I recall, it wasn't very much. You can also find out about their help getting coverage for wigs too.
Try this number: 1-800-227-2345. They are really nice and can help you with whatever is available in your area. I think I called them and they told me about the gas program, I didn't see it online. They sent me a $25.00 gas card, which was handy.
Put in your zip code and click on "assistance" and it comes up with all sorts of help.
I think it is awesome that the ACS sponsored a post on your blog.
I've considered supporting ACS instead of another BC organization which I won't name. I like the fact they support all cancers as well as more of the money goes to research. In addition, cancer research in one area often benefits another especially hormonal breast and prostate cancer. In any case, I do believe it is a mission better served together rather than separately.
Thanks Ann for the links n phone numbers! Really helpful!


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Authorities of the National Oil Company of Liberia (NOCAL) say its attention is drawn to "erroneous" media reports charging the Board of the Corporation of excessive Board fees, unnecessary foreign travels, running the day-to-day activities of NOCAL, and proceeding outside of its mandate with respect to organizing a bid round for potential oil blocks offshore Liberia.
NOCAL clarified in a release that in keeping with its statutory obligations, it is taking proactive steps to revive Liberia's potential oil and gas sector and all its actions are, and will always be taken in accordance with the new petroleum law of Liberia and other internationally acceptable standards.
NOCAL specifically refutes and describes as unfounded, the allegations of the Board being involved in the day-to-day activities of the corporation; that Board members receive sitting fees for each meeting, excessive allowances, and make unnecessary travels.
The day-to-day activities of NOCAL are executed by the Interim Management Team with all financial instruments being subject to the approval of the Minister of Finance and Development Planning, who is also a statutory member of the Board of NOCAL.
The Board has not taken sitting fees, and its allowances have not been determined. Bid rounds for potential oil blocks offshore Liberia will be planned and executed in accordance with Liberia's new petroleum law.
The focus of the Board, whose responsibility it is to set general polices, provide oversight and direction of the corporation, is to support and work with the incoming management team to rebrand NOCAL through strategic reforms that will revitalize its activities and make it attractive and competitive in executing its mandate.
NOCAL assures the public and its partners of its unrelenting commitment to transparency, accountability and other principles of good corporate governance. And as required by the New NOCAL Act, the corporation will report to the public.
NOCAL encourages media entities with interest in reporting about the institution and the country's oil sector to do so with professionalism and a deep sense of responsibility.


All players will be required to attend the joint tryout(s) for Burlington Jr Cougars Rep and Burlington Bulldogs MD. All players will receive a minimum of 3 skate opportunities as teams are being rostered.
Are you missing Tryouts due to injury?
Players who are unable to attend tryouts are still required to register online and pay a Tryout Fee. This Tryout Fee will ensure the player has an opportunity to earn a position on a team. Notification must be emailed to [email protected] accompanied by a Dr. Note. Player MUST provide a further Dr's Note confirming the player can return to skate and an opportunity will be set up to skate with appropriate team(s).
All refunds and/or player release must be requested in writing via email to [email protected] and to your team(s) Head Coach and Manager. Upon receipt of this message, a mutually agreeable meeting will be set up with Directors of the BJC.
As of September 15th - There will be NO Refund/Release Request Meetings granted, unless for medical or residential move(s).
Player Tryout Fees are non-refundable.
An Administration Fee will be charged.
Once all Administration Fee(s) and Player Equipment Deductible(s) have been accounted for a monthly "Hockey Cost" will be divided by six (6) months and will be reimbursed for each month following the player's release from roster. Notification of the release from roster must be submitted to [email protected] in writing and are only applicable for medical or residential move(s).
Once all Administration Fee(s) and Player Equipment Deductible(s) have been accounted for a monthly "Hockey Cost" will be divided by six (6) months and will be reimbursed for each month following the player's release from roster. Notification of the release from roster must be submitted to [email protected] in writing and are only applicable for medical reason(s).


ESF Sports coaches and ESF Language & Learning teachers and staff may occasionally use cameras and videos during sessions and classes for technical feedback/assessment, in the case of sport, or for use in promotional publications and on our website.
If parents do not wish us to use photos that include their child, please advise us on the application form or, in writing.
We understand that parents will want to take photographs and videos of their child.
We also have an obligation to protect children from the inappropriate use of photographic images.
Please be reminded that ESF owns the copyright of all photos and video footage taken at ESF organized classes or events.


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Q: Assign a vector to the last row of a matrix: MATLAB I want to replace the last row of a matrix with a vector.
For example, I did the following and got the error shown:
L = [1 2 3
     4 5 6
     4 6 7]

J = [1 4 6]

K = L(end,:)=J
K == find(L(:,end)=J)
                  ↑
Error: The expression to the left of the equals sign is not a valid target for an assignment

I tried a different code but ended up with
K = find(L(:,end)==J)
ans = 9

The result I wanted was
K = [1 2 3
     4 5 6
     1 4 6] % This last row is now equal to J

Any help would be appreciated.

A: You can do it easily by taking a copy from L. Then replace it:
K = L;
K(end, :) = J;

The expected result is K.

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HorizonBlue.com
Health News Topics
Improving Quality
Serving Our Members
NJ's Health Advocate
Gold-Standard Treatment for Opioid Epidemic Available to More New Jerseyans
Research evaluating the 2017 anti-opioid law called for more medication-assisted treatment. Horizon BCBSNJ's partnerships with three virtual care providers deliver care where and when it's needed most.
Stepping Up To Create More In State Treatment Options
By Rachel Goldberg, Director of Behavioral Health Partnerships and Product Development
The 2017 New Jersey law aimed at curbing the state's opioid epidemic has made significant progress, but much more still needs to be done to battle a crisis that continues to take thousands of lives each year.
That's the conclusion from a multi-phase study evaluating the law's impact that was conducted by the Rutgers Center for State Health Policy through a $132,000 grant from Horizon Blue Cross Blue Shield of New Jersey (Horizon BCBSNJ). According to the center's reports, the legislation contributed to reductions in opioid prescribing and increases in access to treatment.
While the Rutgers study found that the law helped remove barriers to evidence-based medication-assisted treatment (MAT) for people with substance use disorders, the state's capacity to provide MAT remains limited. It's estimated that only one-quarter of addiction treatment providers in New Jersey offer the approved medications, including buprenorphine/naloxone and naltrexone [1].
Several doctors interviewed for the study said they were not interested in providing MAT – which combines medication and behavioral therapy – "seeing this as beyond their scope of expertise [or] impossible given the structure of their practice," according to the report.
"MAT is considered the gold-standard treatment for opioid use disorder," said Alkesh Patel, MD, FASAM, a board-certified psychiatrist in addiction medicine and Behavioral Health Medical Director for Horizon BCBSNJ. "If we're going to be successful in helping New Jerseyans enter and remain in long-term recovery, expanding access to MAT is essential. The fact that many health professionals, for a variety of reasons, refuse to become MAT providers is a very significant problem."
This need has been compounded by the COVID-19 pandemic, which is bringing a surge of mental health problems and substance use disorders along with soaring levels of anxiety and unemployment claims. In April alone, calls to two New Jersey mental health hotlines climbed by 37 percent that month compared to the same period last year, according to data from the state Department of Human Services.
While Horizon BCBSNJ didn't foresee the pandemic, its leaders did realize they needed to add MAT capacity for its members. In May, Horizon BCBSNJ launched a comprehensive program to expand treatment options with three partners that all share the goal of helping members receive MAT in a way ideally suited to these challenging times.
WorkIt Health, Eleanor Health and Kaden not only provide MAT but do so virtually, so members can get the care they need safely and more conveniently. Here's a more detailed look at these three new Horizon BCBSNJ partners:
Eleanor Health takes a whole-person approach to managing substance use, including opioids, alcohol, nicotine, and other substances, treating both the physical and mental symptoms of addiction at the same time. That's why along with medications, Eleanor Health participants are supported by a variety of tailored services, including individual and group therapy, psychiatric services, nurse care management, and peer recovery support.
These sessions can be delivered through Eleanor Health's clinics or via their telehealth program. Members can meet with Eleanor Health care teams online to receive all services, including medication for addiction (often referred to as MAT).
"Everyone is unique, so each person needs an individualized care plan which may include any combination of medication for addiction, other mental health needs, therapy and recovery support," said Dr. Nzinga Harrison, Co-Founder & Chief Medical Officer of Eleanor Health. "We closely monitor our members' progress to ensure their care plan is as effective as possible."
According to Eleanor Health, MAT can triple the likelihood of someone sustaining long-term recovery. This treatment not only helps prevent fatal overdoses and reduce substance use but also is proven to help people stay employed, keep up with family responsibilities and improve their overall quality of life.
"We recognize that more addiction care needs to be brought to neighborhoods that have been long underserved while keeping it financially affordable," said said Srishti Mirchandani, Co-Founder & New Jersey General Manager. "Our partnership with Horizon BCBSNJ allows us to do this in a timely way that supports recovery on a larger scale."
WorkIt Health
WorkIt Health offers Horizon BCBSNJ members struggling with opioid use disorder ongoing buprenorphine/naloxone treatment via a Web or phone app, along with online therapy by licensed counselors. Members can take therapeutic interactive courses to support their recovery and mail in drug tests to verify that they're keeping sober.
"Before we even started in New Jersey, there was a wait list from Horizon members because there was so much pent-up demand," said WorkIt co-CEO and co-founder Lisa McLaughlin. In addition to its online programs, WorkIt Health currently has a clinic location in Hamilton Township in Mercer County, with plans to open additional locations throughout the state in the coming months.
McLaughlin and co-founder and co-CEO Robin McIntosh are both in long-term recovery from substance use disorder themselves. They knew the limitations of traditional recovery programs and wanted to bring their digital expertise to an area of mental health that felt like "a horse and buggy in a world of self-driving cars," said McLaughlin.
WorkIt Health's outcomes are showing that this digital model may indeed be superior. About 84 percent of WorkIt participants are engaged in the program after one month, and those in the program for six months or more are abstinent from their drug of choice 90 percent of the time.
"Our adherence rates beat those of traditional treatment by 60 percent, for one-tenth of the cost," said McLaughlin.
Kaden's Virtual Medication-Assisted Treatment (vMAT) platform may use cutting-edge virtual technology but it doesn't lose sight of the very human aspect of recovery.
Each participant is assigned a Kaden Advocate, who helps with onboarding, coordinating initial appointments and managing members' experience throughout treatment. Advocates can be reached via talk or text so members can get ongoing support and communicate with their entire health care team from anywhere using the vMAT platform.
Partnering for the future
The Rutgers report indicated that MAT prescriptions have grown in New Jersey in the past few years. To change the long-term health outcomes, however, it will take more forward-thinking providers and payers, like Horizon BCBSNJ.
"Many health plans are late adopters to using new technology, especially in this space," said McLaughlin of WorkIt Health. "Horizon has been an innovative partner that looks to the future, knowing how to balance short-term goals with long-term gains."
Horizon BCBBSNJ members in need of help with substance use disorder can sign up directly with any of these providers or use the Doctor/Hospital finder to locate a treatment provider.
1. PRESS RELEASE: Workit Health Expands Telehealth Addiction Care Program to New Jersey. WorkIt Health, October 2019.
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Wearing a mask isn't just good for others – it's good for you too. Check out the recent research about masks cutting infection rates while possibly making the disease milder.
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inMotion is excited to announce the launch of their latest web design for CBRE and Synergy Investment's 51 Melcher Street. This newly renovated commercial building is located in the heart of Boston's Innovation District – a melting pot of commercial real estate for the high-tech, trendy eateries and public spaces.
Using the property's new branding colors, inMotion's design team created a slick and contemporary site and divided it into the following three themes: "Discover", "Connect" and "Create". A striking home page introduces the concept and relating color scheme. Tinted overlays sit on top of high quality images adding an innovative twist throughout, showcasing the building and its surroundings whilst emphasizing the branding.
Users can easily download access maps, spec plans and vacant floor plans. inMotion also developed an interactive map which allows the user to locate amenities using an expanding menu and scroll over markers to highlight their situation on the map.
As the website is integrated with a CMS (content management system) the client is able to have full control of the finished website and manage the content themselves after the launch.


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Home National Former Turkish PM Davutoğlu launches new party opposed to 'leader cult' politics
topheadline
Former Turkish PM Davutoğlu launches new party opposed to 'leader cult' politics
A former Turkish premier and ex-ally of President Recep Tayyip Erdoğan launched a new party on Friday, saying it would stand against "cult of the leader" politics, AFP reported.
Ahmet Davutoğlu, who served as prime minister between 2014 and 2016 and was chairman of Erdoğan's ruling party, formally presented the Future Party (GP) at a ceremony in Ankara.
"As a party, we reject a style of politics where there is a cult of the leader and passive personnel," Davutoğlu said, standing beneath a large banner featuring the revered founder of the Turkish Republic, Mustafa Kemal Atatürk.
Davutoğlu, 60, did not mention Erdoğan by name during his nearly one hour speech but criticized the sweeping powers given to the presidency under constitutional amendments passed in a 2017 referendum.
"It won't be possible to have a democracy with the system continuing like this," said Davutoğlu, who resigned from the ruling Justice and Development Party (AKP) in September.
Analysts say Davutoğlu is seeking to peel away conservative Muslim voters from the AKP, and while few expect him to attract more than a fraction of the electorate, it could be enough to cause problems for Erdoğan.
Davutoğlu insisted his party would stand for minority rights, the rule of law, freedom of the press and an independent judiciary — in a swipe at the deterioration of civil rights during Erdogan's 16-year rule.
He described party's ideological stance as "liberalism with reverence for traditional values."
There are Turkish citizens with Greek, Armenian and Assyrian roots among the founding members, one party official underlined, according to the T24 news website.
Once a close ally of Erdoğan, the two men fell out over a number of issues, most notably the changes to the constitution, and he was forced to resign as premier in May 2016.
He is not the only former Erdoğan ally challenging the president. Ex-economy minister Ali Babacan is expected to launch his party later this month.
Davutoğlu previously served as foreign minister during a particularly rocky period in Turkey's international relations in the early 2010s.
He has been fiercely criticized as the architect of Ankara's efforts to take a more assertive stance across the Middle East — backing the Muslim Brotherhood and its allies in several countries, and supporting rebels in Syria — which ultimately left Turkey with few friends in the region.
Davutoğlu
Future Party
leader cult
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We had tried to get all the messy, tear-the-boat-apart tasks done before moving aboard. Looks like we might have to give ourselves a failing grade on that one!
For the third weekend in a row we have completely dismantled our living space for projects. This weekend it was to re-run the freshwater plumbing and add a filter. The "marine" filter we had originally installed conked out a few hours before our last crossing (and after only a few hours of use). We had lost half of our fresh water before we even made it to the Bahamas. This time we have a simple one from Lowes, the universal cartridges are cheap and will hopefully be easier to find.
Kai was quite the helper at removing all the floor boards. The noisy, ratcheting screwdriver proved irresistible.


text:
Blanc SIMI 8 - Blanc - SIMI 8 - Chimie du solide, colloïdes, physicochimie
One-Photon Ionization of DNA: from electron ejection to oxidative damage – OPHID
DNA oxidation by absorption of low energy UV radiation
Oxidizing capacity of UV radiation: high and low energies
Quantify the electrons ejected from DNA and follow the evolution of the resulting radicals
When DNA loses an electron it undergoes a series of transformations likely to modify the genetic code. Such a loss may be provoked by chemical reactions involving other molecules present in the cell or triggered by ionizing radiation. Absorption of UV radiation directly by DNA may also induce electron ejection provided that its energy is sufficiently high (wavelengths longer than 200 nm). The OPHID objective was to examine whether low energy UV radiation (wavelengths longer than 260 nm) is capable of producing the same effect and determine the probability of such events. <br />Working with various DNA systems in aqueous solution, we have characterized the primary chemical species underlying oxidative damage, the ejected electrons and the resulting base radicals. As these species are not stable during the time, we have recorded their UV-visible absorption spectra on the nanosecond to millisecond times scales, after excitation with nanosecond UV laser pulses. We interpreted our results in the light of quantum chemistry calculations. In addition, we have searched oxidation markers using analytical chemistry methods.
Experimental and theoretical study
Combined experimental and theoretical approach based on (i) steady-state and time-resolved absorption spectroscopy, (ii) chromatographic quantification of final products and (iii) quantum chemistry methods. OPHID involves work with single and double strands. As guanine runs are known to have the lowest ionization potential among the DNA bases and are encountered in DNA telomeric sequences, the study focuses also on guanine quadruplexes
Our study showed clearly that absorption of low energy UV photons directly by DNA may generate base radicals with a probability 10-3. Such a probability is comparable to that corresponding to formation of other well-known lesions induced by the same energy UV radiation. Base radicals disappear on the millisecond timescale and their lifetime is longer in double helices compared to single strands. Oxidation markers have been detected following both UVC and UVB irradiation of genomic DNA.
R. Improta, OPHID partner, obtained a «Chaire d'Alemebert (Idex)« at 'Université Paris Saclay. He will be hosted at LIDYL (2017-2018); research project: "Towards the study of the interaction between Nucleic Acids and protein by Time Resolved optical methods: insights from Quantum Mechanical calculations"
A COST project entitled: «EU-DNA network : understanding damage repair and developing novel DNA sensitizers«, to which all three OPHID partners participate, has been submitted.
Scientific productions and patents
The results obtained in the frame of OPHID have given 17 articles published in international journals and presented in 12 international conferences (11 invited lectures). A special effort was made to communicate the outcomes of our research to photobiologists, in particular thought publications and conferences specific to this community.
Submission summary
The loss of an electron from DNA is one of the primary events leading to damage of the genetic code. It is known to occur through photosensitized processes involving other cellular components as mediators or by the direct effect of ionizing radiation. Yet, electron ejection can also take place following absorption of a single UV photon, provided that its energy is sufficiently high. In the case of DNA bases, this process has been extensively studied for excitation up to ca. 200 nm. However, a few studies have shown that electron ejection from DNA can be triggered by photons corresponding to the lowest absorption band peaking around 260 nm with a weak intensity tail till 400 nm. Thus, the UVA and UVB components of the solar light reaching the surface of the Earth could behave as direct oxidants, in addition to their ability to produce free radicals in cells, and to induce dimerisation of pyrimidine bases in DNA. Consequently, understanding the detailed mechanism(s) of the UVA and UVB action on DNA is an important public health issue and requires ground-breaking fundamental research.
The objective of the present project is to study the factors that govern one-photon ionization of DNA in aqueous solution and describe successive events leading to the formation of final products. To this end, we will use a combined experimental and theoretical approach based on (i) steady-state and time-resolved absorption spectroscopy, (ii) chromatographic quantification of final products and (iii) quantum chemistry methods. We will work with single and double strands. As guanine runs are known to have the lowest ionization potential among the DNA bases and are encountered in DNA telomeric sequences, we will also focus on guanine quadruplexes.
The three participating teams have gained an international recognition for their recent contribution to DNA photophysics and photochemistry. The group of D. Markovitsi (team 1) was the first one to demonstrate the collective behaviour of DNA bases within helices and realize a series of pioneering time-resolved experiments from the femtosecond to the millisecond time scales. The group of T. Douki (team 2) has developed state-of-art analytical tools for the characterization of DNA lesions. R. Improta (team 3, international collaborator) has achieved full quantum mechanical description of the excited state relaxation of DNA components. Team 1 has long-standing and fruitful collaborations in the field of DNA with both team 2 and team 3.
Our strategy will consist of a three-step approach. First we will monitor the hydrated electron in order to determine the quantum yields for its formation after irradiation in the UVA, UVB and UVC spectral domains. These experimental results, obtained for various base sequences, will be correlated with the corresponding calculated ionization potentials. In a second step, we will quantify a wide array of well-known oxidative lesions and determine the quantum yield of formation of these photoproducts as a function of the irradiation wavelength. Finally, knowing the UV absorption spectra of the relevant photoproducts, we will search for their fingerprints in the time-resolved signals and, thus, establish the reaction dynamics. In parallel, quantum chemical calculations will provide a description of the reaction paths on the atomic level.
Madame Dimitra Markovitsi (Centre National de la Recherche Scientifique) – dimitra.markovitsi@cea.fr
The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.
IBB/CNR Instituto Biostrutture e Bioimmagini/Consiglio Nazionale delle Ricerche (Italie)
INAC/SCIB Institut Nanoscience et Cryogénie
CNRS Centre National de la Recherche Scientifique
Help of the ANR 322,355 euros
Beginning and duration of the scientific project: January 2013 - 36 Months
Permanent link to this summary on the ANR website (ANR-12-BS08-0001)
See the publications in the HAL-ANR portal
ANR makes available its datasets on funded projects, click here to find more.


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← Yes–Manchester O2 Apollo, 10/05/14
These and the Other Guy – Self-titled →
The Rodeo Falls–The Fulford Arms, 30/05/14
Posted on June 4, 2014 by Ian
Aaah, pub gigs. Not usually the best venues – in my experience there are usually too many people there more for the drink than the music and they tend to get in the way, both visually and sonically – but The Fulford Arms (and The Woolpack) should be congratulated for promoting original live music, as opposed to the covers bands of some venues.
Strictly speaking, this was a co-headline gig, but I didn't know that until after I had arranged to go along to see The Rodeo Falls. Nor could we work out why we hadn't come across These The Other Guy before, given that they have been active around York since at least early last year and they have already recorded an album.
They opened with two songs about greed, the first a sort of reggae/funk vibe then Like A Queen coming across as a bit more blues, with Gergo Kendick's keyboards weaving their way through and around Andy Elmslie's guitar. The subject then switched from greed to love and the sound changed again, this time to jazz, complete with piano and a sultry mid section. "We're going to slow things down," announced vocalist Alex Botham before they played Chocolate. By this time I was at the bar and found myself so entranced by a track as silky as my favourite foodstuff that I had to be told it was my turn to be served… This was definitely reminiscent of the archetypal smoky jazz-clubs that you see in popular media and it was almost a shame when the next track saw the band get "back into the groove" with a much livelier song that included an extended jam-like instrumental section. They finished the first half of their set with Leave Them By The Door, a musically fun, vocally fast and repetitive number.
After a short break, they returned with a short, snappy opener which was followed by another seeming change of style, this time to something a bit country. I assume by now you have worked out that is was nearly impossible to hear what was being said between songs, hence the lack of titles. However, it was easier to identify Where Did My Children Go? because I did manage to hear that it was in support of the War Child charity. This one opened with just piano and vocals, before Elmslie came in on clarinet, with Geoff Earp (bass) and Pete Spencer (drums) providing a subtle backdrop. It was a slow, sad track that would probably have been a lot more powerful in a more attentive crowd. After Botham said something about Eurovision, the mood changed dramatically into a sort of pop-rock track with soft guitar solo somewhere in the middle. By this time, with the set coming to its end, it was getting harder and harder to hear what was going on and the band were, from where we were sitting, providing little more than background music. I enjoyed what I heard, but I think the set could have been a couple of songs shorter, perhaps by dropping the two cover versions that were included. There's no doubt that, while the music was pleasant enough, the main attraction was Botham – she is clearly a confident front-woman, engaging and expressive in her performance with a lovely voice. I am aware that I haven't mentioned one member of the band – Andy Wilson, I think, is their main song-writer and was providing backing vocals. Unfortunately, from where we were (and using my old ears) I couldn't pick him out of the mix.
I had been wanting to see The Rodeo Falls for a while and the reason for going along this time was that, with one of the band heading off for parts new, it was being advertised as the last gig with this line-up. In fact, they will be playing a short set at MorMusic's Music on Rails Festival at the National Railway Museum in September but, after that, the future of the band is a little uncertain. When I last saw Marck Ck performing solo, my gig buddy for the night asked him what The Rodeo Falls sounded like. Even after he answered we weren't sure and, as he told us tonight, any of the band would give a different answer anyway.
We got one example almost immediately. The opening track started slowly, with dual vocals from Ck and Dave Carpenter, before springing into something very like The Housemartins, complete with an energetic performance which completely fit the style of the song. Doctor Doctor continued the theme, being light and lively after a quiet opening, before Captains of Industry changed the format by opening with a tight staccato opening from the two guitarists leading into an indie/rock 'n' roll crossover. By this time, it was obvious that the sound was completely different to the previous band, much livelier and danceable, as evidenced by the Fulford Arms' chef, who had vacated the kitchen and could be seen grooving along to the music. The band were clearly enjoying themselves on stage and, it has to be said, my feet were already tapping.
Their was a brief pause in the music while bass-player Bob Jackson ("I don't normally talk…") announced that it had been Ck's birthday the day before. The audience partook in a sing-along of Happy Birthday while a cake was produced and Ck, although confessing to a number of food allergies ("I could probably eat the candles…"), said he appreciated the sentiment.
I had heard Ck perform the next song solo so, unlike most of the audience, knew that the answer to his question of "who was the first man into space" wasn't Yuri Gagarin. (For the record, he was the first to return from space, at least according to conspiracy theory.) I still don't know the song's name, and can't remember what it sounded like in solo form, but tonight it was slightly more ballad-like, with a strong, powerful ending. I thought Woe Betide Me came next, although a photo of the set-list with just one-word titles doesn't include anything that looks like that. It's subtle guitar sound was counterpointed brilliantly by the next track, whose scratch-funk led into a fast, furious and very fun sound included energetic drums from Mike Bilson and a fair bit of cossack-like yelping. The next one was slow and so quiet as to be barely audible above the noise of a room which was gradually filling up. Thankfully, what followed was much more brash. Gig-buddy Marc, said it reminded him of Gomez and I had to admit to another void in my musical knowledge. The dual vocals worked well and, by this time, more than the chef was dancing, with the area in front of the stage having been taken over as a dance floor and people at the bar swaying along as well. I'm fairly certain it was the music and not the alcohol… By now, it was practically impossible to see what was happening on stage but, by the sound of things, the band were having as much fun as the audience. The music continued in a lively fashion and, this time, the set ended too soon. The crowd shouted for more but, sadly, no encore was forthcoming.
This entry was posted in Live Music and tagged Fulford Arms, The Rodeo Falls, These And The Other Guy. Bookmark the permalink.
1 Response to The Rodeo Falls–The Fulford Arms, 30/05/14
Hi Ian
Thanks for the great review! We're really excited to hear your feedback. Thanks for the positive and helpful comments. Such a fab time playing with The Rodeo Falls and at the lovely Fulford Arms.
Keeping an eye out on your site! Thanks again.


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Q: How to cumulative update Windows SP1 fresh installation in Virtual Box to the latest update till Jan 2020 I sometimes work with Windows 7 in Virtual Box and install it using SP1 ISO. Now my goal is to install all updates till the end of support using an offline and fast method.
How do I achieve this?
Update:
My preference for methods are:

*

*Official ISO

*MSU installers (split into any number of packages as long as they don't take hours to finish)

*Unofficial/Custom ISO/Virtual Box Image

A: I have a Windows 7 Pro machine using VMware.  Just run Windows Updates. It is still updating what can be updated. No Feature updates, but security and Office updates still update and install.
If you are building multiple machines (why?) then you would need to add the updates to your image, but you can still do this.


2007 El ratón de campo y el ratón de ciudad: Fabula de Babrio. Adaptaciõn de Noe Bofarull. Illustrated by Rosa Sàndez. Primera edición. Paperbound. Barcelona: laGalera fábulas: La Galera, SAU Editorial. $12 from Christian Tottino, Buenos Aires, through eBay, May, '16.
Here is one of three books in a series that includes "manualidades" -- handicrafts generally -- and a scissors on the cover of each book. The "handicraft" consists in cutting out parts for and then assembling a representation of each of the characters. This version of TMCM spends time on the style of life of each mouse. The country mouse lives a contented life of cultivating his garden and enjoying simple pleasures. The town mouse lives in a dumpster and is habituated to the smells of rotten fish and old vegetables. The latter visits his country cousin and reacts negatively as soon as the latter offers him some of the day's fruits of his garden. "Ay, primito, mio, qué mal vives!" After a few days, the country cousin comes to the city, and the two enjoy a banquet on Swiss cheese, dates, and honey. A fruit delivery man interrupts and almost inadvertently breaks their necks. The country mouse loses his appetite but they return to the feast -- but a cat appears and wants to pounce on them. After a long wait in a hole, the country mouse goes off, admitting that his food is not as good but happy to be able to run away from the city's dangers. The final story illustration on 19 gives a good idea of the cartoon illustration style, strong on blocks of vivid color. The two mice are constructed using colored paper, a scissors, glue, and colored pencils.
2007 La cigarra y la hormiga: Fabula de Babrio. Adaptaciõn de Noe Bofarull. Illustrated by Ricard Aranda. Primera edición. Paperbound. Barcelona: laGalera fábulas: La Galera, SAU Editorial. $12 from Christian Tottino, Buenos Aires, through eBay, May, '16.
Here is one of three books in a series that includes "manualidades" -- handicrafts generally -- and a scissors on the cover of each book. The "handicraft" consists in fashioning a representation of each of the characters. This version of GA starts with the ants and their song while they work marching in a column. The artist's style is unique in several ways. He enjoys picturing musical notes, as when the grasshopper sings in front of a music stand and a microphone -- apparently for only his own pleasure inside the studio (9). Aranda also combines drawing with photography skillfully, as when the drawn ants gather around pictured furniture in winter (7). That furniture even includes a telephone! His art form tends to exaggerate head sizes. This grasshopper is quite defensive and outspoken when an ant challenges him: "Don't you like my singing? I'll have just as much to eat when winter comes." When winter does come, the musical notes lie in disorder in the snow underneath and around the hungry grasshopper. I read the French to say that the ant tries to teach him a lesson by telling him to dance to get over the cold. The two characters are constructed using modelling clay, paper clips, and toilet paper.
2007 El león y el mosquito: Fábula de Esopo. Adaptaciõn de Noe Bofarull. Illustrated by Roger Simó. Primera edición. Paperbound. Barcelona: laGalera fábulas: La Galera, SAU Editorial. $12 from Christian Tottino, Buenos Aires, through eBay, May, '16.
Here is one of three books in a series that includes "manualidades" -- handicrafts -- and a scissors on the cover of each book. The "handicraft" consists in fashioning a representation of each of the characters. This version of "The Lion and the Mosquito" leaves out the usual second phase of the story, in which the victorious but arrogant mosquito flies right into a spider's web! All the creatures of the forest try to give King Lion a sense of not lording it over others. The mosquito, among the smallest creatures in the forest, takes him on. The challenge of the mosquito makes the lion laugh, but the last illustration shows the bandaged nose that the lion gets for his trouble. The two characters are among the more complicated to construct in this series of books.


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Q: Liquidgraph does not support bolt+routing in the url? I'm trying to use this liquidgraph tool to manage our schemas on neo4j and endup in a situation where to url below works

jdbc:neo4j:bolt://neo4j:7687

but this one

jdbc:neo4j:bolt+routing://neo4j:7687

I get

ERROR com.hubrick.recommendation.Neo4JMigrationExecutor - Migration
  failed error=java.sql.SQLException: JDBC URL is not correct.

Apparently from what I can see the neo4j driver that liquidgraph is using does not support routing yet?
routing for us is really important since we have cluster and without rounting it might happen that the migration will run in the FOLLOWER and not in the LEADER and then fail right away since it does not have writing access.
So is the any option to make it work?

A: The issue was that the neo4j driver didn't support routing yet, luckily a new version was on the way so basically for now just exclude the current driver from liquigraph project and import the version

    <dependency>
        <groupId>org.neo4j</groupId>
        <artifactId>neo4j-jdbc-driver</artifactId>
        <version>3.3.1</version>
    </dependency>

and routing will be supported.


We've perfected and modernised traditional drying techniques to create our delicious, healthy dog treats. Find out how we do it.
Fish is an extremely perishable item and requires preservation if it is to be suitable for future use. Several preservation methods are used around the world to ensure the fish will be of a very high quality in the coming months and years. The aim of all these methods is the same, to extend shelf-life. One of these preservation methods is drying, which is the oldest known method of preserving perishable food items including fish. The Vikings introduced the drying of fish into the UK around 1,200 years ago in the 9th Century AD.
The term "drying" 'is actually the "dehydration'' of a food product and involves removal of water content from the fish body. Drying fish can take several days, but by doing so we keep proteins and intrinsic nutritional properties intact. This drying process is practiced under controlled operational parameters like air temperature, relative humidity, air velocity etc. Our practice is to dry fish in an enclosure provided with facilities to control these parameters and guarantee that no outside contamination will be allowed.
Our first step along the process is to source high quality fish and fish co-products. Most of the fish we source comes right off the docks here in Grimsby, but we also source from other corners of the UK like Scotland, Bridlington and Anglesey.
At this point we'll carefully fold or twirl our handmade products into shape while the skin is fresh and wet. If we're creating products like our Fish Skin Cubes or Fish Finger Skins, we press lots of the wet skins into boxes that are then frozen into blocks ready for cutting into the required shapes.
The products are then laid out onto trays and put onto racks into the dryer where warm air will be gently circulated to extract the moisture from the skins, leaving a tough, nutritionally dense treat. We monitor the temperature and the moisture level of the skins carefully throughout the process to ensure they come out just right.
All that's left after that is to pack them up and send them off to our customers. It's a simple process that requires great raw materials, care and attention, all of which we have in abundance here at Skipper's.


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BACON PHAT
BACON PHAT PODCAST
Iodine: Why You Need It, Why You Can't Live Without It by David Brownstein, MD
Iodine by David Brownstein, MDBacon Phat
Iodine: Why You Need It, Why You Can't Live Without It is an excellent companion to our Episode 6 book, The Thyroid Connection. It discusses a lot of useful facts about the importance of iodine to the thyroid and body.
In this episode, we discuss:
When Julia eats mostly carnivore or only carnivore, she always has less gas
People argue they poop less on carnivore
Sasha has been eating sushi, pork rinds, peaches, and bananas on AIP
Episode 6: The Thyroid Connection by Amy Myers, MD
Bacteria can influence the body's estrobolome
Iodine is used as a dough conditioner in conventional bakeries
People think a diet with 0 of something is better than a diet with 1 drop of it
Dr. Brownstein's website
Videos in which Dr. Brownstein talks about iodine
Selenium is crucial for thyroid function
Iodine has always been important
Iodine was the first isolated nutrient that scientists discovered was important for health in the United States. They quickly added it to salt to prevent goiter, which was widely prevalent in the Midwest. However, humans had already been supplementing with iodine to prevent goiter—they just didn't know it. 3,500 years ago, the Chinese knew that eating seaweed and burnt sponge would prevent goiter, but they obviously didn't realize iodine was the cause.
Iodized salt is a major source of iodine in the Standard American Diet, but unfortunately it is not very bioavailable. While using iodized salt can be sufficient to prevent goiter, it cannot adequately supply all the iodine needed for "optimal thyroid function". Dr. Brownstein says the only reason doctors don't see iodine deficiency as a widespread problem is that they don't test for it. If one has to live in a place that inherently has lower levels of iodine, it is best to get iodine naturally from sea vegetables and soil or high-quality supplements like iodoral.
Halogens compete with iodine
As we discuss in Episode 6, Iodine is crucial to health because it is required to make the various thyroid hormones. Iodine falls in the second-to-the-right column of the Periodic Table with a group of elements all missing one valence electron. These so-called "halogen elements" include chlorine, bromine, and the most reactive element in the PT, fluorine. Fluorine is present naturally in the earth's crust and therefore our bodies, but it is rarely stored in its elemental state due to its reactivity. We do not believe that overconsumption of fluorine is a good idea for health, so we eschew things like fluoridated toothpaste and water. Just because elements are found naturally in our bodies does not mean that we can consume more of them without consequence.
The halogens compete with iodine in the body because they are chemically similar due to their missing valence electrons. However, it is not correct that halogens are similar in size. We disagree with Dr. Brownstein that one reason the elements act similarly is their similar sizes because the elements' radii increase as you go down the PT. Fluorine has 9 protons and 9 neutrons, so its radius has to be smaller than iodine, which has 53 protons and various amounts of neutrons (Iodine has 37 known isotopes). In fact, because chlorine, bromine, and fluorine are all smaller than iodine and their valence electrons closer to their nuclei, it is harder to remove their valence electrons, making them more reactive than iodine and better able to take iodine's place in the body.
Bromine is a common and highly toxic element in things like new cars, pesticides, and flame retardants. Fluorine, always in a compound form, is used in refrigeration systems, to make things like Teflon, and to fortify water and toothpaste. Chlorine is used in pesticides, synthetic rubber, plastics, solvents, paints, and more. Because these elements are so prevalent in our environment, they have ample opportunity to enter the body and reduce the body's ability to take up iodine. The best solution is to avoid extra sources of them as much as possible. They are present in foods and nature naturally, but there is no reason to give the body extra work by eating conventional food, using conventional materials in homes and cars, and using toxic beauty and cleaning products.
Organification of iodine
Though we (and most other people) use the term "iodine" almost exclusively, there are two forms of iodine necessary for health. Iodine is the diatomic form of the element by itself, and iodide is the ionic form of the element in a compound with another element. (This is why iodoral contains both forms.) For example, iodide must be oxidized via thyroid peroxidase (TPO) to create iodine, which can be used to make T3 and T4, the body's useful forms of thyroid hormone. Interestingly, hydrogen peroxide (a byproduct of ATP production) is a cofactor in this process, and when one is deficient in iodine, excessive hydrogen peroxide, which is toxic for most of the body's cells, can build up.
Dr. Brownstein writes that vitamins B2 and B3 are also necessary for this process, so even if one is getting adequate iodine, she can still have a poorly functioning thyroid and excess hydrogen peroxide (and a cascade of other health issues) because she is not taking in enough B vitamins. (Hello vegans!) Inadequate selenium can also contribute to excess hydrogen peroxide because glutathione peroxidase is necessary for turning hydrogen peroxide back into water.
Iodinated lipids, such as delta-iodolactone, are necessary for more than just thyroid functions. Science tends to forget that the body is complex, and things have multiple uses throughout the body. Delta-iodolactone is necessary for programmed cell death to function correctly. Cancerous cells are successful largely because apoptosis, or programmed cell death, does not occur, and tumors proliferate indefinitely. Iodine deficiency is also implicated in several cancers because other parts of the body, including the breasts, eyes, thymus, pancreas, etc., use iodine to carry out their functions.
The body makes four types of estrogen. (On the podcast, we mistakenly say "three".) Xenoestrogens, which are manmade chemicals that mimic estrogen in the body and interfere with normal hormonal processes, can increase one's risk of breast cancer because they throw off the natural balance of the types of estrogen in favor of estradiol and estrone.
If one has an autonomous nodule on her thyroid, she should not necessarily supplement with iodine. The nodule is not responding to the hypothalamus and pituitary glands and is therefore not regulating T3 and T4 levels correctly. Supplementation with iodine in the presence of an autonomous nodule can result in hyperthyroidism.
Radioactive iodine is often the treatment prescribed for nodules on the thyroid because doctors want to kill the malfunctioning thyroid tissue. However, this practice is risky because it will accumulate in other places where iodine is used. Because the breasts use plenty of iodine as well, when one takes radioactive iodine, it will gather in the breast tissue, increasing the risk for breast cancer.
Major critiques
We love this book. It is helpful and a great little primer for important things to keep in mind about iodine and thyroid health. However, several concepts are not fully explained or explained well, and a lot of supplemental research and reading is needed to understand everything. The graphics aren't great, either.
Dr. Brownstein is an iodine genius. This book is crucial if you have any doubts that iodine is essential to your health. Or if you just need a refresher. It's good to remember that the body is complex and things we don't think about everyday are keeping us alive and need our attention. Read this book for an explanation of iodine's importance for the thyroid and several other biological processes, including apoptosis. Take the graphics and simplified explanations with a grain of salt, however. This book is an excellent jumping-off point, but you will need to read more sources for a pull picture of this life-saving element.


I received an unsolicited copy of this from the publisher and aside from the title making me giggle continuously (seriously it took about 200 pages before I stopped giggling), I figured everyone needs to be more "kind, compassionate, and accepting of [ourselves] so I thought I'd give it a go.* Unfortunately, it wasn't for me.
It's not even that the book was poorly written or that the subject matter is a bit too hokey for me it's not. I've ready hokier things. I think for me it was the repetitive monotony of Kaiser's vague references to things that she chose not to discuss (i.e. her former drug problems?). Why allude to them constantly and then not talk about them? Maybe she discusses it in another book, but for the number of times she mentioned it I kept waiting for that story and it never materialized.
Sometimes you need to be reminded that you don't know everything and this is one of those instances. It legitimately, is a book telling you not to always believe what you're mind says, but to take time out and look at it from a different perspective (aka your heart) and to see what else is going on.
This isn't one of those books I would pick up and buy for myself or even as a gift, but it's one of those books that everyone would (or really should) read if they stumbled across it. I know if I saw it on a coffee table or in a bathroom (see photo of illustration below), I would flip through it. The publicist for the novel sent over a copy for me to check out* and it was a quick, fun and quirky read. I'm definitely going to have to check out the author's website to see what other fun things they get up to.


In the last few installments (first, second, third, and fourth) of this series, we saw how "reduce" can be used to build up a scalar value (such as a number or string), or even a simple collection, such as a list (in Python) or an array (in Ruby). The jewel in the data-structure crown for these high-level languages is known by many names: Dictionary, hash, hash table, hash map, and mapping. I tend to use these quite a bit, and I know that I'm not alone; hashes are easy to use and work with, have O(1) lookup characteristics, guarantee the uniqueness of their keys, and make the code self-documenting. What's not to like?
There are times when you might want to build a dictionary step by step, and "reduce" can help you to do that. I should note that recent versions of Python offer "dictionary comprehensions," which are one of my favorite features of the language, and can be used similarly to "reduce" — and probably with less confusion among new programmers. Nevertheless, I find it interesting and instructive to see how we can use "reduce" to create a data structure that we wouldn't normally associate with this function.
I should note that some of the things you're going to see here are not really recommended coding practices, particularly in Python. But they will be fun, which is important, no?
So this is nice, but perhaps there's a way to have "reduce" build up a dictionary all by itself? The answer is "yes, but" — because Python tries hard to stop us from modifying data structures within a lambda. But if we're willing to be a bit weird, we can get around that. How? By taking the dictionary that we received from the previous iteration (i.e., "output"), turning it into a list of tuples with dict.items, adding that list to our current pair, and then turning the whole thing back into a dictionary.
Note that while this is unwieldy, it doesn't violate one of the key tenets of functional programming, namely treating data as immutable. However, putting this sort of code in a production system will lead to hatred from your colleagues, job security, or (if you're really lucky) both. Oh, and it's probably rather inefficient as well, although I'm not crazy enough to actually benchmark it.
That said, consider what we've done here: We create a new dictionary with each iteration, passing it to "current". The new dictionary is created by taking the old one, breaking it into a list of tuples, adding to it a new tuple, and then turning it all into a dictionary again.
The above code takes advantage of the fact that "and" and "or" are short-circuit operators. Thus, we first invoke d.update on our dictionary. That returns None. Our "or" operator then says, "Well, I'd better go to the second argument, because the first one returned a false-y value. Sure enough, our dictionary — because it isn't empty — is a true value, which is what the statement returns. And sure enough, we get our dictionary.
A final way to do this would be to hide the assignment of the dictionary behind an external function. That is, we have a function do the dirty work for us. That'll certainly work, although I see it as somewhat less fun than lambdas and trying to work around their limitations.
Fun stuff! And, perhaps, the worst method ever for getting an ASCII table into a dictionary.
Next time, we'll see how to do this with Ruby.


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Q: Replace elements in a matrix (Need help to make this faster) C is composed of elements of the array B and i want to change each element which would correspond to A
#Program Block starts

import numpy as np
A= np.array([1, 2, 3, 4, 5])
B= np.array([1, 5, 3, 9, 15] )

# I have a 3*3 matrix

C = [[0 for x in range(3)] for x in range(3)]
C[0][:]=[1,5,3]
C[1][:]=[7,9,15]
C[2][:]=[2,9,15]

flag=(A==B).astype(int) # comparing for equality of 2 arrays A and B, and storing as binary

C_new=np.copy(C)

flag_ind=[i for i, e in enumerate(flag) if e==0] # storing the indices of non differing elements

for x in flag_ind:
    C_new[C_new==B[x]]=A[x]

The output will be C_new=[1, 2, 3; 7 4 5; 2 4 5]
The actual sizes of A and B are ~ 600000 , size of C is 4000000*4.. time for simulation is taking ~ 14 hrs.. If there is a way to do the same operation with greater speed ..kindly let me know

A: This way you are iterating over the entire C array as many times as the intersection between A and B.
What I suggest is creating a dictionary that maps the B values to the A values so that you can retrieve every equivalent element in approximately constant time.
This is what I did, it took 9s to run with arrays of the same size as you specified.
A_dict = dict((k, v) for k, v in zip(B, A) if k != v)
map_c = np.vectorize(lambda x: A_dict.get(x, x))
C_new = map_c(C)

First I created the dictionary to map every value from B that has a different equivalent on A, then I created the function that will use this dictionary on the C array.


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Companies (Share Capital and Debentures) Amendment Rules, 2023. | 10 MB
Posted by rtsprofessionalstudy on January 23, 2023
New Delhi the 21st January 2023
G.S.R.-In exercise of the powers conferred under sub-section (2) of section 42, sub-clause (ii) of clause (a) of 43, sub-clause (d) of sub-section (1) of section 54, sub-section (2) of section 55, sub-sections (1) and (3) of section 56, sub-section (1) of section (62)m clause (f) of sub-section (2) of section 63, sub-sections (10 of section 64, clause(b) of sub section(3) of section 6,7, sub-section (2) and (6) of section 68, sub-sections (9) and (10) of section 68, sub-sections (3) and (6) of section 71, sub-section (13) of section 71 and sub-sections (1) and (2) section, 72, read with sub-sections (1) and (2) of section 469 of the Companies Act, 2013 (18 of 2013), the Central Government hereby makes the following rules further to amend the Companies (share Capital and Debenture) Rules, 2014, namely:-
1. Short title and commencement.- (1) These rules may be called the Companies (Share Capital and Debentures) Amendment Rules, 2023 They shall come into force with effect from 23rd January, 2023
(2) They shall come into force with effect from 23rd January, 2023.
2. In the Companies (Share Capital and Debentures) Rules, 2014-
(a) for sub-rule (14) of rule 17, for sub-rule (14), the following sub-rule shall be substituted namely-
"(14) There shall be a declaration with the return filed with the Registrar in From No. SH.11, signed by two directors of the company including the managing director, if any, certifying that the buy-back of securities has been made in compliance with the provisions of the Act and the rules made thereunder.";
(b) in Annexure.-
(i)for Form No. SH-7, From No. Sh-8, and From No. SH-9 the following forms shall be substituted, namely.-
Download full PDF
Share-capital-and-Deb-20230121 (3)
Companies (Appointment and Qualification of Directors)Amendment Rules,2023 | 1 MB 20-01-2023
Companies (Misc) Amendments Rules,2023 | 655 KB 20-01-2023
Inviting comments of all stakeholders on draft amended Recruitment Rules for the posts of Company Prosecutor(Group'B' Gazetted), Senior Technical Assistant (Group' B' Non-Gazetted) and Junior Technical Assistant (Group'B' Non- Gazetted), Ministry of Corporate Affairs regarding. | 4 MB 20-01-2023
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Long-Term Index February 2018
You are here: Home1 / News Room2 / Unternehmen3 / 20184 / Long-Term Index February 2018
February 2018 was very sunny with low precipitation and comparatively weak winds
Total production from wind and solar power significantly below average at 9,154 GWh
Solar power rank: 3 with 1,722 GWh, wind power rank: 30 with 7,432 GWh
The general weather situation over Europe changed in February. A dominant high-pressure area particularly influenced the second half of the month. Atlantic low-pressure areas could not prevail and, thus, February 2018 was very sunny with low precipitation and comparatively weak winds. The usual sunshine duration in Germany in February increased by 150% and the usual amount of precipitation by 41%. Stormy gusts, similarly to Bft. 8, were measured only in the low mountain ranges and on the coasts. A special storm event was not recorded.
Solar power production increased to 3rd place according to UBIMET's long term-index with 1,722 GWh. This was due to the many hours of sunshine in February 2018. More solar power production was only generated in 1986 with 1,755 GWh and 2003 with 2,068 GWh.*
February was a very weak month for wind power production because of weak low-pressure areas. The all-time production rank was 30 with 7,432 GWh and is thereby in the last third of the last 40 years. The most wind power was produced in 2002 with 18,053 GWh.*
In total, 9,154 GWh of energy was generated by wind and solar farms last February. This is slightly above average compared to the last 39 years. The most profitable February for the total of wind and solar energy was in 2002 with 19,146 GWh* due to high solar energy production.
* The UBIMET long-term index compares the solar and wind energy production yields. The UBIMET experts calculate the respective yields for each month of the last 39 years and compare them to the current values. Every yield is related to the current German portfolio so that the periods can be compared.
Energy Data & Forecasts
Long-term Index January 2018
UBIMET is a leading commercial provider of precise meteorology services and severe weather warnings and the first global digital weather service provider. The global company is headquartered in Vienna, Austria and has offices in Karlsruhe, Melbourne, Munich, New York and Zurich employing 250 staff from 25 nations. UBIMET provides high-quality meteorological data, forecasts and alerts enabling weather-dependent industries around the globe to increase safety and efficiency.
UBIMET's expertise and reliable weather solutions have convinced customers from industries such as aviation and rail, construction, energy, insurance, media as well as event organizers. UBIMET has delivered accurate weather data to Formula 1 teams since 2014.
The company was founded as a start-up by Michael Fassnauer and Manfred Spatzierer in 2004. The two founders, driven by a passion for meteorology, are still the driving force behind the company today. Red Bull has been a strategic partner since 2012.
Since 2015 the UBIMET Group has had an office in Karlsruhe, Germany.The company was founded as EWC Weather Consult in 1999 and was rebranded to UBIMET in November 2017 and is the competence centre for energy and insurance within the group.
Contact UBIMET
Long-Term Index May 2018
11. June 2018 /in 2018, 2018, Langzeitindex, Long-term Index, News Room, Unternehmen /by Karin Schwarz
https://www.ubimet.com/wp-content/uploads/2018/06/renix-201805-monthly.png 357 845 Karin Schwarz /wp-content/uploads/2016/04/ubimet-weather-matters-logo.png Karin Schwarz2018-06-11 12:08:502018-06-11 12:08:50Long-Term Index May 2018
Less Feed-in Management in April 2018
25. May 2018 /in 2018, feed-in management, News Room /by Karin Schwarz
https://www.ubimet.com/wp-content/uploads/2018/05/EinsMan-Monitor_Germany_2018-04-01_2018-04-30_deutsch-1.png 376 845 Karin Schwarz /wp-content/uploads/2016/04/ubimet-weather-matters-logo.png Karin Schwarz2018-05-25 14:03:312018-05-25 14:19:30Less Feed-in Management in April 2018
Long-Term Index April 2018
8. May 2018 /in 2018, 2018, Langzeitindex, Long-term Index, News Room, Unternehmen /by Karin Schwarz
https://www.ubimet.com/wp-content/uploads/2018/05/Long-Term-Index-April-2018.png 506 1200 Karin Schwarz /wp-content/uploads/2016/04/ubimet-weather-matters-logo.png Karin Schwarz2018-05-08 16:05:002018-05-08 16:29:20Long-Term Index April 2018
UNIQA UBIMET Severe Weather Report 2017 Long-Term Index March 2018


Our Country Club & RV Resort is a 55+ gated community just mins. from Phoenix. Full of Big Rig Sites/Park Models to Rent or Purchase a Home. Enjoy our 18 Hole Golf Course/Pro Shop/Restaurant/Lounge/Pool/Spa & more.
This is perhaps the cleanest and best maintained RV facility I have seen. Its a huge park with a few hundred RV sites and many other sites that have modular homes on them. Its is above all else a GOLF RESORT and is a gated community with fulltime security. Jets from the nearby air base do fly about 5 days a week and can be a bit noisy at times. I have a month here at a premium site where electricity, cable and wifi are all included and so far all those services work as expected with little issues. The staff and service people are all exceptional in offering assistance and information. The amount of activites offered is amazing from water aerobics to painting to glass work. They have an awesome billard room. The location on the west side of Phoenix is pretty nice, just 10 minutes off the 101 and I10. All needed local facilities such as food, gas, etc as well as dozens of restaurants all with in 15 minute drive time of the park. In park services for garbage curbside pickup twice a week is free, local propane service comes into the park 3 days a week and is easily scheduled to stop by your RV to fill. Wash.Wax services can be purchased as well as any needed maintenance work. This is a high class park and you can see it in all the rigs that are here. I figure for $1000/month for what we are getting is unbeatable and we don't even play golf.
I stayed here for two months. The park is clean and beautiful. That is the only good thing that I enjoyed. This is the noisiest park I have ever been at. The jets from Luke air force base fly directly over the resort head 5 days a week. you cant even hear to speak.I was over charged for my electricity. If that is not bad enough , most of the people are in there 70 ies , and then I was forced out on the 31st of the month ,when I was supposed to leave on the first.. They hit the golf ball and they land any place. get ready for possible damage to you vehicles. My truck was almost hit on several occasions. I was there two months and my electric bill was over 240.00 without using any air conditioning! Then you have to post a 250.00 refundable deposit to get it turned on! the resort offers electricity too get it started! Beware I saw 4 other people that were forced to leave on the 31st and were overcharged! Unless you are close to 80 I would stay far away from this place!!!!!!
Ok, there are some things that have changed here and not all of them good. I used to like coming to this park but they nickle and dime you to death. Be prepared to pay for your ENTIRE reservation upfront with a check ONLY! No credit/debit cards allowed. MAKE SURE YOU AGREE WITH THEIR CANCELLATION POLICY. $30 monthly for WIFI, Electricity is not provided and you must go through the local provider that charges a $25 connection fee. 9 cents per kwh at the time of this posting. (not bad) Cable is $30 - two trash bag limit on twice weekly garbage pick - up and there are no dumpsters on the grounds. I realize that the word 'expensive" is a relative term. This park is expensive compared to what is offered. This park is nice and is well kept. The pools and hot tub area is nice. The mini gym is adequate. If you come in for a week or two - this park is perfect. Longer stays? Well, not so much - very cliquish and not prone to mix and mingle activities. Do yourself a favor. If you are going to stay in the area for longer than a week or two, look at other parks that are the same price but offer oh so much more. I wish we would have looked before we leaped.