text:
Propane Jane™ on Twitter
What's more shameful is the White American majority voted for Trump precisely so this would happen, and the more he justifies such heinous actions by calling the undocumented "animals" the more his approval rating rebounds. #ThisIsAmerica https://t.co/BniLkXOBrE
Propane Jane discusses how the deplorables' dehumanization of marginalized groups has paved the way for dismantling of every civil rights advancement of the 20th Century and the illegitimate ascendancy of #InstabilityInChief via @RickSmithShow https://t.co/TbOLdvca2D
The Next Michael Jackson
This little dancer made a big impact last week on #NationalIndigenousPeoplesDay in Camrose, Alberta.
Two-year-old Albert Apsassin who loves to sing and dance, finally got his first opportunity to dance in front of a big crowd.
Video: Martina Josephine pic.twitter.com/hzkqEne0Lo
— APTN National News (@APTNNews) June 28, 2018
Senior Ice lawyer sentenced to prison for stealing immigrants' identities | US news | The Guardian
A senior lawyer for Immigration and Customs Enforcement (Ice) has been sentenced to four years in prison for stealing the identities of immigrants facing deportation and using them to to take out credit cards and run up more than $190,300 in debt. Raphael Sanchez, formerly the lead attorney for the Seattle Ice office, also used the photograph of a murdered woman on some of the fake identities he created and claimed several deported immigrants as dependents to dodge tax collectors.
Source: Senior Ice lawyer sentenced to prison for stealing immigrants' identities | US news | The Guardian
Trump Threatens Harley-Davidson, Saying It 'Surrendered' – The New York Times. My Comment
Trump is not negotiating trade deals! He is setting new taxes! His tariffs raise the price of certain commodities and categories of goods, and also make business and consumers prices higher. Because trade is part of the global supply chain, it resists government action. Building economies of scale is best for a single nation's interests.
Economic growth is pinned to demand; new production follows a template:
1. Infrastructure in housing/transportation/public services (talk to anybody who has landed a site contract);
2. Business clusters and supply chains (why 5 West Virginia counties lead in US polymer chemical exports);
3. Financing and regulation (West Virginia again, tax breaks must go into research), and
4. Economies of scale (global relations Trump overlooks).
The US political economy also reveals racial thresholds larger than the trade deficits. The black income gap (70%) and the black employment gap (2X/twice the white rate) have remained roughly constant for 50 years. "Together are they the fixed costs of racism?"
Trump's lower unemployment numbers didn't change the disparity. Black workers remain unemployed at twice the white rate. Their wages are lower. Structural racism remains–the gap persists in the face of black success.
Public Shaming Feels Good. That's No Reason to Do It. – The New York Times. My Comment
The new political mass psychosis is rooted in a strange place—comfort/ugliness as a lifestyle. Stripped of the flag, parades, the anthem and winning, America has arrived at a point where racist inhumanity is a broad lifestyle, with school shootings and gun ownership and death by addiction; with mass killing teenagers and paying for silence about non-existent sex, and breathing-while-black. Government agents removed breast-feeding children, children too young to know the meaning of a promised ten-minute video call.
Civil–? Who are the Blessed? The Mercy givers? Not Trump! He prefers oppositional-defiant swag to prayer and works, his hell-raising full of loud blame never tells the full story and ignores peace, the path of the poor. Not Trump. His thrill is the absurdity that the US, the world's leading arms merchant with record sales, is a global victim, raked over for jobs and cash.
His Jericho-in-America gives money to the wealthy, then blames nations, friends and foes. Neither prophet, messenger, or sanctified, nothing in his mind is greater than himself, including his sins. Trump believes in his own measure. He dangerously ignores any downside or complicated evidence in his decisions. He recasts limits and complications as blame rather than errors.
[https://www.nytimes.com/2018/06/26/opinion/maxine-waters-public-shaming-trump.html?comments#permid=27639265]
Public Shaming Feels Good. That's No Reason to Do It. By Frank Bruni Opinion Columnist June 26, 2018 1026 Image Maxine Waters caused controversy Monday night when she encouraged voters to take inspiration from the recent public shaming of Trump administration officials.CreditAndrew Caballero-Reynolds/Agence France-Presse — Getty Images For a solid week, the most discussed story in America — the one that dominated serious newscasts and owned the home pages of influential periodicals — was the Trump administration's cruel separation of migrant families and detention of some children in de facto cages. The outrage transcended political party, forced President Trump to change course and represented an all-too-rare instance when his reprehensible actions earned a properly disgusted, widespread rebuke. "The dumbest thing in American politics" is how a Republican strategist described the mess that Trump had needlessly made. "The dumbest, dumbest thing." So why, when the strategist said this to me, did he sound upbeat? The answer is that it was Monday night and a miracle had occurred: The Democratic Party — well, one Democratic congresswoman in particular — had given journalists a different story to turn to, and this new narrative allowed Trump and his enablers to play the parts of victims. "Thank you, Maxine Waters," the strategist said. Waters, rightly apoplectic about Trump, had exhorted voters to take inspiration from the recent public shaming of Trump administration officials and harass and heckle them whenever opportunity struck. "You tell them they're not welcome anymore, anywhere," she said. [Also read Michelle Goldberg on what she describes as a crisis of democracy, not manners.] And, predictably, a significant chunk of the talk in the news and on social media focused on whether the country had descended to some unfathomed nadir of acrimony. Weeping children on the border ceded the stage to screaming adults in Washington restaurants. "Inhumanity" made way for "incivility," a noun that was being applied to Trump's supporters and his detractors and was thus obscuring the maliciousness of the former. Nancy Pelosi took to Twitter to do damage control. Chuck Schumer, on the Senate floor, issued a sort of apology. Democrats showcased internal divisions rather than a united front and, in the parlance of sports, blew their lead. Let's put aside the question of decorum and how we get back to a place where political debate is constructive and Congress is a realm of problem solving and progress, not a modern-day Colosseum in which gladiators do grisly battle. Let's focus instead on tactics. Does public shaming serve the cause of thwarting Trump and limiting his considerable damage to America? The answer is more likely no than yes, and I don't think that we can take that risk when a man is this miserable and the stakes are this high. Public shaming competes with the very developments that illuminate those stakes. The Supreme Court just validated Trump's Muslim — er, travel — ban. Harley-Davidson announced that it's moving production and jobs outside of America. There are constant fresh revelations about the ethical squalor of members of Trump's cabinet. Let's direct voters toward the red meat of their wrongdoing, not their indigestion when they go out for a chimichanga. It's possible that public shaming will have no effect on voters' feelings and decisions, which are largely baked in by now. But it's also possible that public shaming intensifies an ambient ugliness that sours more Trump skeptics than Trump adherents, who clearly made peace with ugliness a while back. And those adherents, nursing a ludicrous sense of persecution, could turn out in greater numbers this November as a result. It's also the case that Trump can't win on facts, which is why he has no regard for them, or on policy, which is why he's cavalier about it. But resentment? Fury? That's the toxic ecosystem in which he thrives. He'd like to turn all the country into a Trump rally. If the noise is loud enough, no signal can be heard. Trump's opponents say that it's not fair that their confrontational conduct draws censure when his own conduct is more confrontational — and is heartless and racist to boot. They're right. It's not fair. But you know what's less fair? This presidency itself. And you know what would be even less fair than that? Trump's getting another two years with an obsequious Republican majority in Congress and, heaven help us, a second term. The stain on America could be indelible. Preventing it takes precedence over all else. So what matters now isn't what's viscerally satisfying and morally just. What matters is the absolute best strategy. What matters is victory. And behavior that could imperil that victory can't be encouraged on the grounds that it's reciprocal and feels good. "I'm outraged all the time," a friend said to me near midnight Monday. "You want to know what I'm doing with it? I'm going to polling
Uses and Abuses of Economic Formalism – The New York Times. My Comment: Tj
Trump and the media are too concerned with him! That concern misses key economic details and great stories! Trump's Pavlovian box box of blame feeds the media into reporting a closed cycle of stories and that strip context and skip details and concepts.
Missed Details–pundits and reporters miss the key stories of the economy: the seismic failure of US corporations/the administration to innovate by modifying best practices and analyzing powerful economic trends. My readers know the stories of Bolsa Familia (Brasil's successful poverty program that focuses income and social benefits on educational success, as education breaks the cycle), the development template success of West Virginia's Chemical Alliance, South Carolina's transportation manufacturing, Phoenix's call centers, and the ultimate template, China's Pearl River zone. You cannot talk about economics without discussing these realities, their details!
Conceptually, the distinction between political corruption and moral debauchery is being blurred and erased. Corruption's new forms mirrors old ones: cronyism, service to special or personal interests, under Trump, a vigorous dedication to xenophobia/racism, a growing global brand of white supremacy taking national form in demands for closed borders.
Conceptually, Trump promotes fear as truth, success by misrepresentation, inflamed by broad falsehoods and scapegoating. He abuses authority, defies the rule of law, and shifts common resources to the rich.
[https://www.nytimes.com/2018/06/27/opinion/uses-and-abuses-of-economic-formalism-wonkish-and-self-referential.html?comments#permid=27662871]
America's Trading Partners Are Having Plenty of Fun Without Us – The New York Times. My Comment: "A Migrant Labor Force"
Were it not for his biases, which causes him to reject economic opportunities; Trump could establish American leadership of global food security, with an executive order. Trump direct Immigration to issue America First visas for America's fishing waters, farms, and agricultural plants, similar to other visas for summer and professional work. Agriculture was the fasting growing segment under Obama, outpacing manufacturing, global growth expanding exports. It's close to crisis under Trump, showing a single year 45% net income drop. Trump tariffs are raising prices on Western farmers with no plan to help, when their annual rainfall is less than 20 inches.
The best agricultural workers in the world are our neighbors. Across the country, America has lost crops in the fields. Data shows declines in production efficiencies. With a clear need for agricultural labor in harvesting, processing, packing and shipping, Trump's racist loathing and blame blocks economic growth more than trade imbalances.
Civil disobedience is a part of the tradition of law. Those workers present themselves offer America a great opportunity.
The US breadbasket can be a global hub for economies of scale, with expanding labor and skills. Instead of immigration, think labor, low wage jobs that are difficult to fill, require skills, and create demand and prosperity. Why are farms and plants not demanding visas for food workers, our best economic bump?
Trump is not negotiating trade deals! He is setting new taxes! He is setting fiat prices–government-determined prices.
Trump is using random numbers for tariffs not tied to any plan or goals. His tariffs (25%?) raise the price of certain commodities and categories of goods, and make business and consumers prices higher. Because trade is part of the global supply chain, it resists government action by quotas or tariffs.
To expand trade, build economies of scale, Soviet gas, for example, or Brasilian coffee. This is the best path for rebalancing a nation's trade interests. We don't need a milk war with Canada! BMW's largest plant, making its luxury convertible, is in a Republican state! Boeing imports. But its profits are not matched to trade–trade balances are not profits and losses.
New economic growth follows a best practices template, not trade war:
1. Infrastructure in housing, transportation, public services (talk to anybody who has landed a site contract);
3. Financing and regulation (West Virginia again, tax breaks must go into research),
4. Economies of scale (a powerful tool of global relations Trump overlooks that China engages).
Economics is an easy way to inflict abuse on communities with a narrative that says their abuse is in everybody's best interests. "Deserving blame" is a favorite Trump technique. His narratives depend upon blame. Without it he has nothing to rail against.
85 Recommend
[https://www.nytimes.com/2018/06/27/opinion/trump-tariffs-allies-trade-deals.html?comments#permid=27643348]
Actually extrapolation is not as big a danger as the academy makes or as we once thought. What is the test of truth is its repetition. Truth has great depth and persistence, it can be found in diverse relationships and differences and and contradictions as well as similarities.


text:
Le Fairphone 3 est le troisième modèle de smartphone de la marque néerlandaise Fairphone. Il est commercialisé en France en .

Caractéristiques
Sa particularité est de se composer de 7 modules aisément amovibles. Cela lui permet donc d'être facilement réparé par l'utilisateur et de se positionner comme plus durable, tout en étant aussi plus équitable. Les pièces peuvent être changées voire évoluer, du fait de la disponibilité de composants plus performants.

Il dispose des caractéristiques techniques suivantes :
 Écran de 5,65 pouces (environ 14,5 centimètres) de diagonale, Full HD, ratio 18/9
 Processeur Snapdragon 632
 4 Go de RAM
 64 Go de stockage (extensible jusque 400 Go à l'aide d'une carte micro-SD)
 Un port USB C et une prise jack
 Batterie de 3040 mAh
 Poids de 189 grammes

Notes et références

Voir aussi

Articles connexes
 Fairphone (smartphone)
 Smartphone
 Téléphone mobile

Liens externes

Fairphone
Appareil sous Android

redpajama_set_name: RedPajamaWikipedia


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text:
Q: How to insert list data into SQLite? I have data in a text file and I extracted specific key and value from them.
Python File
data = []
with open('datatest.txt', 'r', encoding='utf-8') as f:
    for count, line in enumerate(f, start=1):
        if count % 2 == 0:
            data.append((json.loads(json.loads(line)['message'])['first_name'],
                         json.loads(json.loads(line)['message'])['last_name'],
                         json.loads(json.loads(line)['message'])['id'],
                         json.loads(json.loads(line)['message'])['phone']))

Content of Datatest.txt File
{"index": {"_type": "_doc", "_id": "wJgr4m8BAObvGO9GQ4_E"}}
{"message":"{\"_\":\"user\",\"pFlags\":{\"contact\":true},\"flags\":2175,\"id\":379951860,\"access_hash\":\"6967195540985199805\",\"first_name\":\"پژوا\",\"last_name\":\"روزبهی\",\"username\":\"mramtd2\",\"phone\":\"989157145632\",\"photo\":{\"_\":\"userProfilePhoto\",\"photo_id\":\"1631880813210609625\",\"photo_small\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"448413446\",\"local_id\":476387,\"secret\":\"655623158723369503\"},\"photo_big\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"448413446\",\"local_id\":476389,\"secret\":\"13993366131879811943\"}},\"status\":{\"_\":\"userStatusOffline\",\"was_online\":1558046876}}","phone":"989157145632","@version":"1","typ":"telegram_contacts","access_hash":"6967195540985199805","id":379951860,"@timestamp":"2020-01-26T13:50:12.793Z","path":"/home/user/mirror_01/users_5d65f610ec18aa615a5f580c.log","username":"mramtd2","type":"redis","flags":2175,"host":"ubuntu","imported_from":"telegram_contacts"}
{"index": {"_type": "_doc", "_id": "wZgr4m8BAObvGO9GQ4_E"}}
{"message":"{\"_\":\"user\",\"pFlags\":{\"contact\":true},\"flags\":2167,\"id\":104168655,\"access_hash\":\"4049515388751185251\",\"first_name\":\"فرنود\",\"last_name\":\"پولادی\",\"phone\":\"989122802780\",\"photo\":{\"_\":\"userProfilePhoto\",\"photo_id\":\"447400966949546277\",\"photo_small\":{\"_\":\"fileLocation\",\"dc_id\":1,\"volume_id\":\"806513597\",\"local_id\":18178,\"secret\":\"17864732085601779143\"},\"photo_big\":{\"_\":\"fileLocation\",\"dc_id\":1,\"volume_id\":\"806513597\",\"local_id\":18180,\"secret\":\"15235849821352229632\"}},\"status\":{\"_\":\"userStatusOffline\",\"was_online\":1564097832}}","phone":"989122802780","@version":"1","typ":"telegram_contacts","access_hash":"4049515388751185251","id":104168655,"@timestamp":"2020-01-26T13:50:12.793Z","path":"/home/user/mirror2/users_5d38e984ce828ee03a4789ee.log","type":"redis","flags":2167,"host":"ubuntu","imported_from":"telegram_contacts"}
{"index": {"_type": "_doc", "_id": "wpgr4m8BAObvGO9GQ4_E"}}
{"message":"{\"_\":\"user\",\"pFlags\":{\"contact\":true},\"flags\":2167,\"id\":370718330,\"access_hash\":\"10906080075127684980\",\"first_name\":\"گلنسا\",\"last_name\":\"پریی\",\"phone\":\"989139505268\",\"photo\":{\"_\":\"userProfilePhoto\",\"photo_id\":\"1592223103833974699\",\"photo_small\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"434224163\",\"local_id\":12578,\"secret\":\"12430588603747451378\"},\"photo_big\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"434224163\",\"local_id\":12580,\"secret\":\"5910708978456395305\"}},\"status\":{\"_\":\"userStatusOffline\",\"was_online\":1561114212}}","phone":"989139505268","@version":"1","typ":"telegram_contacts","access_hash":"10906080075127684980","id":370718330,"@timestamp":"2020-01-26T13:50:12.793Z","path":"/home/user/mirror_01/users_5d65f610ec18aa615a5f580c.log","type":"redis","flags":2167,"host":"ubuntu","imported_from":"telegram_contacts"}
{"index": {"_type": "_doc", "_id": "w5gr4m8BAObvGO9GQ4_E"}}
{"message":"{\"_\":\"user\",\"pFlags\":{\"contact\":true},\"flags\":2175,\"id\":421775832,\"access_hash\":\"8579095166420383836\",\"first_name\":\"دلکش\",\"last_name\":\"چالاکی\",\"username\":\"Betym11356\",\"phone\":\"989126159776\",\"photo\":{\"_\":\"userProfilePhoto\",\"photo_id\":\"1811513405139429339\",\"photo_small\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"455032489\",\"local_id\":485722,\"secret\":\"12099548278164429458\"},\"photo_big\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"455032489\",\"local_id\":485724,\"secret\":\"313431783423483716\"}},\"status\":{\"_\":\"userStatusOffline\",\"was_online\":1564084837}}","phone":"989126159776","@version":"1","typ":"telegram_contacts","access_hash":"8579095166420383836","id":421775832,"@timestamp":"2020-01-26T13:50:12.793Z","path":"/home/user/mirror2/users_5d38e984ce828ee03a4789ee.log","username":"Betym11356","type":"redis","flags":2175,"host":"ubuntu","imported_from":"telegram_contacts"}
{"index": {"_type": "_doc", "_id": "p5gr4m8BAObvGO9GQ4_B"}}
{"message":"{\"_\":\"user\",\"pFlags\":{\"contact\":true},\"flags\":2103,\"id\":171873228,\"access_hash\":\"13248517514388945915\",\"first_name\":\"ویس\",\"last_name\":\"تورتکی\",\"phone\":\"989372499383\",\"photo\":{\"_\":\"userProfilePhoto\",\"photo_id\":\"738189893774190623\",\"photo_small\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"439634863\",\"local_id\":87854,\"secret\":\"241528711325634206\"},\"photo_big\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"439634863\",\"local_id\":87856,\"secret\":\"6022220707203794397\"}}}","phone":"989372499383","@version":"1","typ":"telegram_contacts","access_hash":"13248517514388945915","id":171873228,"@timestamp":"2020-01-26T13:50:12.792Z","path":"/home/user/mirror_01/users_5d65f610ec18aa615a5f580c.log","type":"redis","flags":2103,"host":"ubuntu","imported_from":"telegram_contacts"}
{"index": {"_type": "_doc", "_id": "qJgr4m8BAObvGO9GQ4_B"}}
{"message":"{\"_\":\"user\",\"pFlags\":{\"contact\":true},\"flags\":2175,\"id\":54581106,\"access_hash\":\"16670232207411597190\",\"first_name\":\"آزاده\",\"last_name\":\"نازچهری\",\"username\":\"mehdiomidii\",\"phone\":\"989121447728\",\"photo\":{\"_\":\"userProfilePhoto\",\"photo_id\":\"234424065705749301\",\"photo_small\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"446735579\",\"local_id\":362838,\"secret\":\"9556479517471012490\"},\"photo_big\":{\"_\":\"fileLocation\",\"dc_id\":4,\"volume_id\":\"446735579\",\"local_id\":362840,\"secret\":\"8435444578550263608\"}},\"status\":{\"_\":\"userStatusRecently\"}}","phone":"989121447728","@version":"1","typ":"telegram_contacts","access_hash":"16670232207411597190","id":54581106,"@timestamp":"2020-01-26T13:50:12.792Z","path":"/home/user/mirror2/users_5d38e984ce828ee03a4789ee.log","username":"mehdiomidii","type":"redis","flags":2175,"host":"ubuntu","imported_from":"telegram_contacts"}
{"index": {"_type": "_doc", "_id": "qZgr4m8BAObvGO9GQ4_B"}}

Now I wanna insert data list value into SQLite. How Can I do that?

A: You need to have a table (for example users) with these columns : id, firstName, lastName, userId, phone.
Then:
for record in data:
    first_name, last_name, user_id, phone = record
    cur.execute(
        'INSERT INTO users (firstName, lastName, userId, phone)'
        ' VALUES (?, ?, ? ,?)',
        (first_name, last_name, user_id, phone))

redpajama_set_name: RedPajamaStackExchange


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text:
Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides
Tei Maki, Satoru Kidoaki, Kengo Usui, Harukazu Suzuki, Masayoshi Ito, Fuyu Ito, Yoshihide Hayashizaki, Takehisa Matsuda
Department of Applied Molecular Chemistry
To characterize the molecular basis of specific interactions of PDZ proteins, dynamic force spectroscopy (DFS) for the PDZ protein Tax-interacting protein-1 (TIP-1) and its recognition peptide (PDZ-pep) derived from β-catenin was performed using an atomic force microscope (AFM), together with measurement of thermodynamic and kinetic parameters using surface plasmon resonance (SPR). The unbinding force of this pair was measured under different conditions of AFM tip-retraction velocity. The relationship between the unbinding force and the logarithmic force-loading rate, that is, the dynamic force spectrum, exhibited two different rate regimes, for each of which the forces increased linearly with the force-loading rate. On the basis of the theoretical treatment of the Bell-Evans model, the positions of two different activation barriers in the reaction coordinate and dissociation rate constants in each barrier were evaluated from slopes and x-intercepts of the two linear regimes (first barrier: 0.04 nm and 1.10 × 10s-1; second barrier: 0.21 nm and 2.77 × 10-2 s-1, respectively). Although two-step unbinding kinetics between TIP-1 and PDZ-pep was suggested from the DFS analysis, SPR results showed single-step dissociation kinetics with a rate constant of 2.89 × 10-1 s-1. Different shapes of the free energy profile of the unbinding process were deduced from each result of DFS and SPR. The reason for such topographic differences in the energy landscape is discussed in relation to the differences in the pathways of forced unbinding and spontaneous dissociation.
Langmuir
https://doi.org/10.1021/la0627011
10.1021/la0627011
Dive into the research topics of 'Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides'. Together they form a unique fingerprint.
Force Chemistry 100%
Surface Plasmon Resonance Chemistry 50%
Protein Chemistry 33%
Spectroscopy Chemistry 33%
Dynamics Biochemistry, Genetics and Molecular Biology 33%
Rate Chemistry 25%
Dissociation Chemistry 25%
PDZ Protein Neuroscience 25%
Maki, T., Kidoaki, S., Usui, K., Suzuki, H., Ito, M., Ito, F., Hayashizaki, Y., & Matsuda, T. (2007). Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides. Langmuir, 23(5), 2668-2673. https://doi.org/10.1021/la0627011
Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides. / Maki, Tei; Kidoaki, Satoru; Usui, Kengo et al.
In: Langmuir, Vol. 23, No. 5, 27.02.2007, p. 2668-2673.
Maki, T, Kidoaki, S, Usui, K, Suzuki, H, Ito, M, Ito, F, Hayashizaki, Y & Matsuda, T 2007, 'Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides', Langmuir, vol. 23, no. 5, pp. 2668-2673. https://doi.org/10.1021/la0627011
Maki T, Kidoaki S, Usui K, Suzuki H, Ito M, Ito F et al. Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides. Langmuir. 2007 Feb 27;23(5):2668-2673. doi: 10.1021/la0627011
Maki, Tei ; Kidoaki, Satoru ; Usui, Kengo et al. / Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides. In: Langmuir. 2007 ; Vol. 23, No. 5. pp. 2668-2673.
@article{0dda9b6547a541b78e61fd36aa6a8c90,
title = "Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides",
abstract = "To characterize the molecular basis of specific interactions of PDZ proteins, dynamic force spectroscopy (DFS) for the PDZ protein Tax-interacting protein-1 (TIP-1) and its recognition peptide (PDZ-pep) derived from β-catenin was performed using an atomic force microscope (AFM), together with measurement of thermodynamic and kinetic parameters using surface plasmon resonance (SPR). The unbinding force of this pair was measured under different conditions of AFM tip-retraction velocity. The relationship between the unbinding force and the logarithmic force-loading rate, that is, the dynamic force spectrum, exhibited two different rate regimes, for each of which the forces increased linearly with the force-loading rate. On the basis of the theoretical treatment of the Bell-Evans model, the positions of two different activation barriers in the reaction coordinate and dissociation rate constants in each barrier were evaluated from slopes and x-intercepts of the two linear regimes (first barrier: 0.04 nm and 1.10 × 10s-1; second barrier: 0.21 nm and 2.77 × 10-2 s-1, respectively). Although two-step unbinding kinetics between TIP-1 and PDZ-pep was suggested from the DFS analysis, SPR results showed single-step dissociation kinetics with a rate constant of 2.89 × 10-1 s-1. Different shapes of the free energy profile of the unbinding process were deduced from each result of DFS and SPR. The reason for such topographic differences in the energy landscape is discussed in relation to the differences in the pathways of forced unbinding and spontaneous dissociation.",
author = "Tei Maki and Satoru Kidoaki and Kengo Usui and Harukazu Suzuki and Masayoshi Ito and Fuyu Ito and Yoshihide Hayashizaki and Takehisa Matsuda",
doi = "10.1021/la0627011",
journal = "Langmuir",
T1 - Dynamic force spectroscopy of the specific interaction between the PDZ domain and its recognition peptides
AU - Maki, Tei
AU - Kidoaki, Satoru
AU - Usui, Kengo
AU - Suzuki, Harukazu
AU - Ito, Masayoshi
AU - Ito, Fuyu
AU - Hayashizaki, Yoshihide
AU - Matsuda, Takehisa
N2 - To characterize the molecular basis of specific interactions of PDZ proteins, dynamic force spectroscopy (DFS) for the PDZ protein Tax-interacting protein-1 (TIP-1) and its recognition peptide (PDZ-pep) derived from β-catenin was performed using an atomic force microscope (AFM), together with measurement of thermodynamic and kinetic parameters using surface plasmon resonance (SPR). The unbinding force of this pair was measured under different conditions of AFM tip-retraction velocity. The relationship between the unbinding force and the logarithmic force-loading rate, that is, the dynamic force spectrum, exhibited two different rate regimes, for each of which the forces increased linearly with the force-loading rate. On the basis of the theoretical treatment of the Bell-Evans model, the positions of two different activation barriers in the reaction coordinate and dissociation rate constants in each barrier were evaluated from slopes and x-intercepts of the two linear regimes (first barrier: 0.04 nm and 1.10 × 10s-1; second barrier: 0.21 nm and 2.77 × 10-2 s-1, respectively). Although two-step unbinding kinetics between TIP-1 and PDZ-pep was suggested from the DFS analysis, SPR results showed single-step dissociation kinetics with a rate constant of 2.89 × 10-1 s-1. Different shapes of the free energy profile of the unbinding process were deduced from each result of DFS and SPR. The reason for such topographic differences in the energy landscape is discussed in relation to the differences in the pathways of forced unbinding and spontaneous dissociation.
AB - To characterize the molecular basis of specific interactions of PDZ proteins, dynamic force spectroscopy (DFS) for the PDZ protein Tax-interacting protein-1 (TIP-1) and its recognition peptide (PDZ-pep) derived from β-catenin was performed using an atomic force microscope (AFM), together with measurement of thermodynamic and kinetic parameters using surface plasmon resonance (SPR). The unbinding force of this pair was measured under different conditions of AFM tip-retraction velocity. The relationship between the unbinding force and the logarithmic force-loading rate, that is, the dynamic force spectrum, exhibited two different rate regimes, for each of which the forces increased linearly with the force-loading rate. On the basis of the theoretical treatment of the Bell-Evans model, the positions of two different activation barriers in the reaction coordinate and dissociation rate constants in each barrier were evaluated from slopes and x-intercepts of the two linear regimes (first barrier: 0.04 nm and 1.10 × 10s-1; second barrier: 0.21 nm and 2.77 × 10-2 s-1, respectively). Although two-step unbinding kinetics between TIP-1 and PDZ-pep was suggested from the DFS analysis, SPR results showed single-step dissociation kinetics with a rate constant of 2.89 × 10-1 s-1. Different shapes of the free energy profile of the unbinding process were deduced from each result of DFS and SPR. The reason for such topographic differences in the energy landscape is discussed in relation to the differences in the pathways of forced unbinding and spontaneous dissociation.
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redpajama_set_name: RedPajamaCommonCrawl


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BABY SWIMMING: Both the literature and practice indicate that children can stand without support starting at around 9 months old.
"But with some training, children can stand much sooner than that, even before they're 4 months old," says Professor Hermundur Sigmundsson at NTNU's Department of Psychology.
Snorri Magnússon teaches a baby swimming course in Iceland. Babies in the programme do various exercises, including standing in-hand and on a corkboard.
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The babies are given the opportunity to stand as part of a 12-week baby swimming course, with twice weekly one hour sessions.
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Of the 12 children who participated in the course that the researchers studied, 11 managed to stand on their own for more than 15 seconds by the end of the sessions. The 12th baby also managed to stand for a good 8 seconds. Instructor Snorri says this is a common experience.
"On average, the children were 4.3 months old when they learned to stand without support. The youngest was only 3.6 months old," says Sigmundsson. He points out that once the babies learn to stand, they don't forget how.
The study can provide us with more information about how we develop balance and the ability to control our movements. Practice also seems to work for the youngest among us. These children are practising how to stand. So they get good at it – very fast and very young.
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This corresponds to other studies Sigmundsson has conducted on mathematical skills. You get good at exactly what you practice, like algebra or equations, not mathematics in general.
This study was a collaborative effort with Associate Professors Håvard W. Lorås and Monika Haga, both at NTNU's Department of Neuromedicine and Movement Science.
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Some children are more aggressive than others when they have bad experiences. But they are also calmer when life is good.


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text:
Shoppers ought to sustainability at the right price
YarnsandFibers News Bureau 2019-12-13 08:41:28 – None
More than three-quarters of fashion customers want to shop more sustainably – but only 39 per cent would be willing to pay more for ethical brands, according to a new report.
The survey of more than 2,000 people was carried out by specialist consultancy Retail Economics as part of a series of reports, entitled Understanding and Influencing the Customer Journey for Fashion, by law firm Penningtons Manches Cooper.
It focuses on purchasing, the second stage of the customer journey, and examines the key trends - such as the secondhand market and clothing rental services – that are changing the landscape for fashion retailers.
These trends also include the continuing rise in online sales, the increasing influence of social media, the ongoing customer desire for the new, and the shift towards conscious consumption to extend the lifespan of fashion.
The survey reveals that Generation Z (18-24 year olds) is the most fashion-conscious group with 31 per cent buying clothes at least once a fortnight – compared to just eight per cent of Generation X (45-54).
But it also found that two fifths of shoppers have donated or traded-in second-hand clothing to a retailer and 72 per cent of those who have not donated would consider doing so in the future.
Matthew Martin, co-head of Penningtons Manches Cooper's fashion and luxury brands team, which acts for a number of high profile brands including Farfetch, said that secondhand and rental clothing were becoming increasingly important.
He said: "With fashion retail sales under pressure as consumers remain cautious in regards to discretionary spending, business models that attract a new type of customer looking for pre-owned clothing, or that provides access rather than ownership, is a strategy that an increasing number of retailers are adopting to bolster revenue and extend the lifespan of clothing at the same time."
Richard Lim, chief executive officer for Retail Economics, said the rapid rise of social media was driving a desire to be seen in fresh outfits more often, which was being supported by fast fashion retail.
But he added: "At the same time, consumers are becoming more concerned about their impact on the environment. The balance between price and sustainability certainly leaves a curious place for clothing rentals and pre-owned markets, as shoppers and retailers attempt to 'do the right thing', simultaneously increasing the lifespan of clothing before it hits landfill and providing a value alternative."
Courtesy: EcoTextile News


text:
West Point Photos
West Point Videos
West Point Virginia
The Crab Carnival is the first weekend in October and basically a good opportunity to support local businesses. The Jammin 'Point concert series takes place every Saturday night from 6-8 p.m. at West Point Community Center.
The West Point Farmer's Market is open every Saturday from 9 a.m. to noon on the corner of Main Street and Main Avenue. It is located just outside the city and is one of the most popular restaurants in the area.
When I was elected mayor, one of my priorities was to increase the resources available to the City of West Point to purchase new buildings and infrastructure. Given the high cost of living and lack of funding from the State of Virginia, it is necessary to maintain a reasonable balance. Finally, I would like to say once again that it has been a pleasure to serve in this capacity for over 20 years as Mayor and Member of the Board of Trustees.
In this budget, I am able to approve tax cuts for taxpayers and, given the current economic challenges we face, the timing could not be better. The Council has been preparing for this reduction in interest rates for several years and we have been able to bring small and medium-sized enterprises up to acceptable levels while continuing to provide resources for urban services. I expect that in the near future we will start the H.O.P.E. initiative to reopen the economy and to involve more companies in the initiative.
There are many ways to enjoy the paddle river in West Point and the Mid Peninsula of Virginia, that's for sure. Chelsea Plantation is a great place for history buffs, and we've put together a few options to explore. Next time you're in West Point, Virginia, you can round it off with a trip to Riverfront Park and Recreation Center, where you can have fun.
The museum contains numerous artifacts that cover the long years of the Pamunkey in the region and even preceded the arrival of the first colonists. West Point covers just 6 square miles and has a population of just over 3,300 people, each of whom knows each other personally or someone else. Much of the city centre is listed as a historic district with a mix of historic buildings, restaurants, shops and shops.
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The population was distributed throughout the city, 17.9% of whom were 65 years or older. The median income of households in the city was $49,655 and the median income of families was $56,932. About 1.3 million people in West Point lived below the poverty line, including 2.2 million children under 18 and 1 million adults.
The city's ethnic makeup was 80% black, 32% white, 2% brown and 1% other ethnic groups. The present site of West Point was once home to the Pamunkey Mattaponi, an Algonquin-speaking tribe that was affiliated with the Powhatan Confederation. More than 350 years later, tribesmen of the Pam unkey (Mattaponsi) continue to occupy the reserve on the eastern edge of the western border between Virginia and North Carolina. It also houses pottery stables, a school and a fish hatchery, but its reserve is the largest of its kind in the United States and the only one in Virginia.
Located north of the York River in the Chesapeake Bay, it is the only point in the United States with a population of more than 1,000 people.
If you want to turn your visit to West Point into a weekend and experience history and special events, then this historic tour is not to be missed. This tour takes you through the historic streets of West Point and gives you an insight into the beautiful architecture that has been preserved for decades. The tour also offers superb views of the Pamunkey and Mattaponi rivers that join the York. Those interested in the general history of WestPoint should not take a closer look at the historical tour.
Of course we all know the infamous West Point Beach, which is not a beach at all, but there is a lot of land from which you have a great view of the rivers Pamunkey and Mattaponi and the town of WestPoint.
Built in 1655, it comprises the former Cinquetock site and overlooks the Mattaponi River. The settlement began as part of a plantation sold by the West family, who were named West Point and had access to the York River, but the settlement reopened in the 18th century.
In the 1890s, much of the Richmond-Danville Railway, including the section between Richmond and West Point, became part of Southern Railway after a financial reorganisation. In the 1980s, the railway was taken over by the Norfolk and Southern Railway Company, which continued to restructure the industry. Port status declined at the end of the 20th century, notably due to a decline in shipping traffic and the closure of ports on the Mattaponi River and the construction of new ports in Virginia.


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Q: How to use multiprocess in another code and funcion? I am trying to multiprocess cell detection via the deepcell package. Because the deepcell detection works fine on small images. But for bigger images it does not work or takes a really really long time.
So I'm trying to cut the images into small patches, and then use multiprocessing to feed them to the cell detection.
I need to be able to run the pool_cell_detection() function in another code, and get its return value (allPoints). Whereas if I use it in a if name=='main' wrapper, then I could not get the return value. Can you suggest how I can do this?
Here is my code1
import numpy as np
import os
import matplotlib.pyplot as plt
import cv2 as cv
from multiprocessing import Pool
from deepcell.mesmer import Mesmer
import time

blevel_image = cv.imread("./images/blevel_eq_p.png",0)
app = Mesmer()

def deepcell_detection(image0, mpp):
    print(type(image0))
    cv.imwrite("./images/image1.png", image0)
    image = np.stack((image0,image0), axis=-1)
    image = np.expand_dims(image,0)
    labeled_image, coords = app.predict(image, image_mpp=mpp)
    print(len(coords))
    return coords

def pool_cell_detection(img_channel):
    blobs_log = []
    r,c = img_channel.shape[0:2]
    mpp = 2
    rstep=r//10
    cstep=c//10
    patches=[]
    for i in range(10):
        for j in range(10):
            img_patch = img_channel[i*rstep:(i+1)*rstep,j*cstep:(j+1)*cstep]
            patches.append([img_patch, mpp])
    with Pool(4) as p:
        print("pooling")
        allPoints=p.map(deepcell_detection, patches)
    return allPoints

def main():
    allPoints = pool_cell_detection(blevel_image)

if __name__ == '__main__':
   main()

I need in code 2 something like the following:

import code1

def func_something():
    #Many operations
    allPoints = pool_cell_detection(blevel_image)

But I'm not sure how to write code 2 to be able to get the allpoints

A: As the multiprocessing documentation says, the entry point of a multiprocessing program must be wrapped in if __name__ == '__main__': when using the spawn start method, which is the only available option on Windows, which you're on.
Change the final invocation from
blobs_log = pool_cell_detection(blevel_image)

to e.g.
def main():
    blobs_log = pool_cell_detection(blevel_image)

if __name__ == '__main__':
    main()

Following up on the comment threads, all in all, you might have, let's say, multiprocessing_cell_detect.py:
import multiprocessing

import cv2 as cv
import numpy as np
from deepcell.mesmer import Mesmer

def deepcell_detection(image0, mpp):
    cv.imwrite("./images/image1.png", image0)
    image = np.stack((image0, image0), axis=-1)
    image = np.expand_dims(image, 0)
    labeled_image, coords = Mesmer().predict(image, image_mpp=mpp)
    return coords

def pool_cell_detection(img_channel):
    r, c = img_channel.shape[0:2]
    mpp = 2
    rstep = r // 10
    cstep = c // 10
    patches = []
    for i in range(10):
        for j in range(10):
            img_patch = img_channel[i * rstep:(i + 1) * rstep, j * cstep:(j + 1) * cstep]
            patches.append([img_patch, mpp])
    with multiprocessing.Pool(4) as p:
        return p.map(deepcell_detection, patches)

and my_cell_program.py:
from multiprocessing_cell_detect import pool_cell_detection

def main():
    blevel_image = cv.imread("./images/blevel_eq_p.png", 0)
    allPoints = pool_cell_detection(blevel_image)
    print(allPoints)

if __name__ == '__main__':
    main()

and you run python my_cell_program.py.
So long as the main entry point of the program is guarded, things will work. The module you import a multiprocessing thing from will not need to be guarded (unless you also wish to use that module stand-alone).


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EU, Blair expect Israel to soften Gaza blockade soon
http://www.alertnet.org/thenews/newsdesk/9504929UT.htm
Israel has agreed in principle to begin easing its three-year-old blockade on Gaza "in days", Middle East envoy Tony Blair said on Monday.
Blair said that after talks with Israeli Prime Minister Benjamin Netanyahu in recent days he believed there was now a willingness to allow the entry of more goods into the territory.
"In respect of the closure policy, I hope very much in the next days we will get the in-principle commitment that we require, but then also steps beginning to be taken," he told reporters, referring to Israeli commitments.
"I believe and hope that over the next period of days we can reach a situation where we get a policy in respect of Gaza that is right for Israel's security and is humane towards people in Gaza," he said.
Blair spoke after talks in Luxembourg with European Union foreign ministers, who issued a statement calling for the Gaza blockade to be lifted and a "credible, independent" inquiry into the May 31 assault on aid ships headed to Gaza.
Israel imposed a blockade on Gaza, a coastal territory of 1.5 million Palestinians, soon after militant group Hamas won legislative elections in 2006, and tightened the restrictive measures after Hamas seized power in the strip in June 2007.
But since the raid on the flotilla last month, when Israeli forces killed nine Turkish men after clashes erupted on board one of the vessels headed to Gaza, it has come under international pressure to soften the measures.
BANNED LIST
The EU wants Israel to move from a policy of banning the entry of almost all goods into Gaza, except a few designated items, and instead adopt a policy of accepting almost all goods and banning only those that are proscribed on a list.
Israel says it maintains the blockade to prevent arms and items that could be used for militant purposes reaching Hamas and other militant groups in the territory.
Blair and EU foreign affairs chief Catherine Ashton said Israel was moving towards accepting a changed position on what is banned, and said the list of proscribed items -- which includes weapons and "dual-use" items" -- would be updated soon.
"I hope we are now in a position to move forward on this," Blair said, referring to altering the list of items, which would maintain a ban on arms, armaments and explosives.
"In other words we change from the so-called permitted list of items where things only come in if they are on that list to the prohibited list where things come in unless they are on that list."
Blair also said he welcomed an announcement by Israel on Monday that it would conduct its own investigation into the flotilla raid, an inquiry that will include two independent, international experts. The United Nations wanted a completely independent inquiry but Israel resisted that.
"The issue of the inquiry will obviously continue to be an issue of strong policy debate," Blair said. "There are many different views on this but the Israeli inquiry is obviously a significant step forward."
Gaza Economic Development


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A rendering of the Ulta Beauty shop-in-shop at Target stores.
Ulta Beauty Delivers Record Sales and Earnings
Beauty is booming and Ulta expects to spend $80 million on supply chain and IT in fiscal 2021. Learn how the retailer is putting technology to use and what it expects for the holiday season.
Jamie Grill-Goodman
Ulta Beauty's Q3 Fiscal 2021
Net sales increased 28.6% to $2.0 billion compared to $1.6 billion in the third quarter of fiscal 2020 due to the favorable impact from stronger consumer confidence and fewer COVID-19 restrictions compared to the third quarter of fiscal 2020.
Comparable sales (sales for stores open at least 14 months, including stores temporarily closed due to COVID-19, and e-commerce sales) increased 25.8% compared to a decrease of 8.9% in the third quarter of fiscal 2020, driven by a 16.8% increase in transactions and a 7.7% increase in average ticket. Compared to the third quarter of fiscal 2019, comparable sales increased 14.3%.
Gross profit increased to $789.5 million compared to $545.5 million in the third quarter of fiscal 2020. As a percentage of net sales, gross profit increased to 39.6% compared to 35.1% in the third quarter of fiscal 2020, primarily due to leverage of fixed costs, favorable channel mix shifts, leverage of salon expenses, and improvement in merchandise margins.
Beauty is booming.
Ulta Beauty CEO Dave Kimbell said cycling last year's disruption from COVID, product newness, and strong performance from promotional events drove all major categories to deliver double-digit comp growth in its Q3 2021compared to Q3 of fiscal 2020.
For the quarter, net sales increased 28.6% to a record $2 billion, he noted on the company's earnings call, and operating profit increased to 14.2% of sales.
"We delivered record sales and earnings, increased our market share, and expanded our Ultamate Rewards loyalty program to nearly 36 million members," Kimbell said in a press release. "This strong third quarter performance reflects the strength and resiliency of the beauty category, the power of the Ulta Beauty differentiated model, and the impact of our winning culture and team."
The retailer also launched Ulta Beauty at Target in 92 stores and online during the quarter. [See more: Target & Ulta Ready Joint Shop-in-Shops]
"We are excited about this innovative partnership and how, together with Target, we will change the way guests experience beauty," Kimbell said. "While it will take time for us to understand what role this new distribution point will play for our guests, we are incredibly pleased with the ongoing customer excitement and encouraged to see Ultimate Reward members linking their accounts with Target Circle, as well as new members signing up through the shop."
The beauty retailer expects to spend between $200-$225 million in capex in fiscal 2021, including approximately $80 million for supply chain and IT. Capital expenditures were $51.1 million for the quarter, driven by investments in new stores, remodels and relocations, supply chain, and IT systems.
"Our teams are excited, engaged, and ready to support our guests from proactively managing inventory flow and anticipating supply chain challenges to stress testing our IT systems and digital platforms to successfully accelerating our holiday hiring," said Kimbell.
Kimbell noted Ulta's holiday season is off to a strong start and he's confident the retailer is well-positioned to deliver another successful holiday season.
"We are excited about the strength we are seeing in our business," he said. "Our third quarter performance exceeded our initial expectations, and we are encouraged by the early holiday trends. The beauty category is recovering, and our teams are executing well."
Looking ahead, Ulta expects to invest $160 million to $180 million in capital over the next three years, with most of the investment planned for fiscal 2022 and 2023. Project SOAR, Ulta Beauty's multiyear effort to upgrade its enterprise resource planning (ERP) platform, is expected to provide a more flexible and scalable operating environment, as well as support future growth and innovation. Ulta believes it will begin to see operational benefits from this investment in fiscal 2023.
In Store Experience
Walmart Promotes Digital Marketplace, Opens 30 New Sam's Club Locations


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Mebane Sheetz to close for about 5 months
BusinessCities and TownsMebane
Drivers looking for a place to refuel or stock up on snacks around Mebane will need to take a detour for a few months.
Starting September 19, the Sheetz located off I-85/40 at 1237 Mebane Oaks Road in Mebane will be closed for about five months for remodeling, a store manager there confirmed Tuesday for The Alamance News.
[Story continues below photographs.]
"It's a full-remodel," the manager confirmed to the newspaper in a brief phone interview Tuesday afternoon. The 6,471-square foot gas station and convenience store was built in 2005, according to Alamance County's tax department.
Completion of the renovation is currently targeted for mid-February or early March 2023, according to the store manager.
Sheetz has three other locations in Alamance County, including two in Burlington and one in Graham, plus the company operates a distribution center in Burlington.
The timing for the remodel also corresponds to considerable NCDOT roadwork taking place in front of the store. The Mebane Oaks Road overpass (immediately adjacent) is being widened, with some corresponding road-widening work along the roadway in front of the Sheetz.
For the most comprehensive business news each week, subscribe now: Just $50 for one year online access. If you're in Alamance County, that rate also includes a printed edition by mail. Sign up now.
Commissioners lend their unanimous support to revised plans for proposed charter school
Six youths arrested Wed. afternoon after crashing stolen vehicle into police SUV


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Kid Convention
Ahead of the 2016 election the Institute asked kids to design their ideal candidates and asked them what they look for in a leader.
Kid Convention 2017
Kids: It's your chance to choose. What issues in your community are most important to you? What qualities should candidates running for local office possess? What can we do in our communities to create a better world? It's up to you to answer these questions at the Institute's 2017 Kid Convention.
A day of engaging hands-on civic activities for children and families
Kid Convention 2019 is a day of fun and engaging hands-on activities for children and families where youngsters learn about the legislative process, government, and the importance of making their voices heard.
Liberty University (formerly Liberty Baptist College) Speech
Monday | October 3, 1983
At a time in which the religious right gained prominence in American politics, Senator Kennedy spoke as a guest of the Rev. Jerry Falwell and called for an end to religious intolerance in American political debate.
Lowering the National Voting Age to 18
Monday | March 9, 1970
With the voting age at that time set at 21 years of age, Senator Kennedy argued that it was wrong that young Americans could be drafted to serve in Vietnam, but could not vote.
Lowering the Voting Age: Then and Now
Join the Kennedy Institute for a virtual conversation on the movement to lower the voting age and the power of coalitions to push for change from both a historical and modern perspective. Participants include an original member of the Youth Franchise Coalition that was instrumental in the passage of the 26th Amendment and current activists working on voting rights and lowering the voting age to 16 years old.
Senator Angus S. King, Jr.
Martin Richard Foundation Day of Service
Kennedy Institute is the service village location
The Kennedy Institute serves as the service village for the Martin Richard Foundation's Spring Service Day. This event provides an opportunity for families to participate together in a day of service around the theme "creating a better world for young people."


Today Todd focused on 2 Peter 1:1-11 and encouraged us not simply to know about God but to have a true knowledge of God through a relationship with him.
People tend toward one of two errors: 1) trying to work hard to earn God's love (Legalism), and 2) simply believing historical facts about the story of Jesus but never actually knowing or walking with him (Licentiousness). Neither error is the gospel. Do you find yourself drift toward one of these errors? Which one, and why?
Peter talks of another way, one with the true knowledge of God. The word he uses for true knowledge denotes a thorough experiential knowledge of something or someone. It is deeper than surface knowledge about facts, it is a knowledge that includes a relationship to the one known. How would you contrast the true knowledge of God with legalism and licentiousness? Is the true knowledge of God a reality in your life?
Read 2 Peter 1:1-4. Who is the one bringing about godliness in the Christian's life? How should that inform the way we read 1:5-7?
2 Peter 1:5 tells us to make every effort, or to be diligent in our faith. This means we deploy all of our resources to grow in intimacy with Jesus. We do not work hard at the Christian life because our hard work produces godliness, but because our efforts are relational investments that deepen our intimacy with the only one who can make us godly. What does relational diligence look like in your life? What are one or two things you can do to cultivate your affection for Jesus? Talk about these with the group then commit to hold one another accountable to practicing them.
Peter says the one who lacks the growth described in verses 5-7 is "so nearsighted that he is blind, having forgotten that he was cleansed from his former sins" (1:9). How do you tend to be nearsighted and what is the natural result of forgetting God's love for you? Why do you think it is so important to keep a perspective of grace and to consistently remember the love and forgiveness of God? What are some practical ways you can be reminded every day of God's love?


Abstract: Abstract Background The Extracorporeal Life Support Organization (ELSO) Maastricht Treaty for Nomenclature in Extracorporeal Life Support (ECLS) established consensus nomenclature and abbreviations for ECLS to ensure accurate, concise communication. Methods We build on this consensus nomenclature by layering a framework of precise and efficient abbreviations for cannula configuration that describe flow direction, number of cannulae used, any additional ECLS-related catheters, and cannulation sites. This work is a consensus of international representatives of the ELSO, including those from the North American, Latin American, European, South and West Asian, and Asian-Pacific chapters of ELSO. Results The classification increases in descriptive capability by introducing a third (cannula tip position) and fourth (cannula dimension) level to those provided in the previous consensus on ECLS cannulation configuration nomenclature. This expansion offers the simplest level needed to convey cannulation information yet allows for more details when required. Conclusions A complete nomenclature for ECLS cannulation configurations accommodating future revisions was developed to facilitate ability to compare practices and results, to promote efficient communication, and to improve quality of registry data.


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The Bromacker Fossil Project Part II: The Hunt for Fossils
New to this series? Read The Bromacker Fossil Project Part 1 here.
Finding fossils at the Bromacker quarry was tedious and physically demanding, but it was extremely rewarding when a fossil is discovered. Our annual summer field season generally lasted three and a half weeks. Because the weather usually wasn't conducive to camping or cooking outdoors, we stayed at the same hotel and dined at the hotel or local restaurants.
The original 1993 fossil quarry was opened using heavy equipment and operators from the nearby commercial quarry, and in the early years we relied on these people to expand the fossil quarry's boundaries as needed. When the commercial quarry was temporarily shut down due to the lack of contracts for building stone, our collaborator Dr. Thomas Martens fortunately was able to obtain funding to annually rent a Bobcat, which he became skilled at operating. Thereafter, Thomas would use the Bobcat to expand the quarry and remove soil and weathered rock layers, so that we could begin our yearly excavation on unweathered rock.
The Bromacker quarry on the first day of fieldwork in the 2006 field season. Shovels were used to clear loose rock from the surface of the quarry. Pictured (counterclockwise from left) graduate student Andrej Čerňanský and Dr. Jozef Klembara (Comenius University, Bratislava, Slovak Republic) and Dr. Dave Berman (Carnegie Museum of Natural History [CMNH]). Photo by the author, 2006.
We would each stake out an area of the quarry to work in and then proceed to work through the rock layers by using a hammer and chisel or pry bar to free a piece of rock. Its surfaces and edges would be checked for fossil bone, and if there was none, the rock piece would be broken into smaller pieces, which were also checked for bone. As is the case at many other fossil sites, the rock tended to split along the plane a fossil was preserved in, because the fossil would create a zone of weakness.
The quarry after a couple days of excavation. Pictured (clockwise from front) are Dave Berman, Jozef Klembara, and Andrej Čerňanský. Photo by the author, 2006.
Once a fossil specimen was discovered—and there were a few frustrating years when this didn't happen—the hard work of extracting it from the quarry began. Here, I'll use a fossil discovered during the 2006 field season as an example of how this was done.
A discovery! Fossil bone and bone impression are exposed to the left of the lens cap. Photo by the author, 2006.
First, we would isolate the fossil specimen from the surrounding rock, exposing as little of the fossil as possible while determining its extent, because it would have been easy to lose pieces of bone in the dirt and mud. Then we would encase the specimen in a plaster and burlap jacket to protect it during extraction, shipping, and preparation.
To make the jacket, we'd coat cut strips of burlap in wet plaster and then spread them across the surfaces of the rock containing the specimen, or block. A layer of plastic (plastic bags worked well) was applied to the top surface of the block to keep plaster from sticking to any exposed bone.
The block is partially isolated from surrounding rock. In this case, we decided to encase the top and some sides of the block in plaster and burlap bandages to hold the rock pieces together before we finished isolating the block from surrounding rock. Photo by the author, 2006.
After a couple layers of plaster bandages were applied to the top and sides of the block, the block was undercut, with plaster bandages added periodically to hold the undercut rock in place.
Pictured (left to right) are Dr. Stuart Sumida (California State University, San Bernardino, CA), Dave Berman, and Mr. Jerome Gores (Museum der Natur, Gotha [MNG]). Jerome is holding a plaster and burlap bandage while Dave and Stuart are pressing plaster bandages against the bottom of the block. They must hold the bandages in place until the plaster sets. Photo by the author, 2006.
Using hammers and chisels to undercut the block. Photo by the author, 2006.
When deemed safe, we would crack the block free from the quarry floor using hammers and chisels, and flip it over, unless it broke free on its own. Excess rock would be removed from the bottom of the block to make it lighter in weight. Then we would apply burlap and plaster bandages to the bottom of the block. The block would be removed from the quarry and stored at the MNG until it was shipped to Pittsburgh.
The block has now been safely flipped over and excess rock is being removed. Photo by the author, 2006.
We encountered several problems during our quarry operations over the years. As we worked our way through the rock column in the quarry, processed rock piled up on the quarry floor. In the early years, we tossed or shoveled the processed rock into wheelbarrows and pushed the heavy, unwieldy wheelbarrows out of the quarry to a dump pile. Fortunately, the Bobcat eventually replaced the wheelbarrows for moving processed rock. As we ran out of space outside the quarry to dump processed rock, the rock was used to backfill older portions of the quarry.
Former CMNH volunteer Linda Rickets (front, right) and the author (left, rear) line up to push loaded wheelbarrows out of the quarry to the dump pile. Photo by Dave Berman, 1996.
At the dump pile. Over time rain and the freeze/thaw cycle would break down the rock and vegetation would grow on it. Photo by Dave Berman, 1996.
Another problem was that fossils found at the bottom of the quarry were often extremely difficult to undercut because the rock so was hard. Sometimes a well-hit chisel would just bounce off the rock instead of cracking or penetrating it. One year we had to resort to a rock saw to undercut a block.
Dave Berman uses a rock saw to undercut a block. Photo by the author, 2004.
Rain was always a problem. We would shelter in our cars during intervals of rain, or work at the museum if the rain was heavy and persistent. Occasionally heavy rain would flood the quarry, forcing us to work in the 'dry' areas of the quarry while a pump drained the water. Of course, we had contests to see who could skip a rock the farthest or make the biggest splash.
A flooded quarry greeted us in the morning after heavy overnight rain. Pictured are Thomas Martens (front) and Stuart Sumida (rear). Photo by the author, 2010.
Next week's post will describe the process of fossil preparation, that is, removing rock to reveal a specimen in the lab. The fossil collected in the 2006 field season will be used as an example.
Here are some videos taken by taken by Thomas Martens' wife, Steffi, during the 1993 and 2006 field seasons. These show the process of searching for fossils (1993 video) and collecting the fossil highlighted in this post (2006 videos).
Bromacker Quarry 1993
https://youtu.be/DAEG0l1NotE
https://youtu.be/UNL1s5ycJSM
https://youtu.be/lqYxheOZLQY
https://youtu.be/HrmSBrhde_E
Amy Henrici is Collection Manager in the Section of Vertebrate Paleontology at Carnegie Museum of Natural History. Museum staff, volunteers, and interns are encouraged to blog about their unique experiences and knowledge gained from working at the museum.
The Bromacker Fossil Project Part III: Fossil Preparation


Home Focus Design & Construction Grand Openings!
New Tradition Homes was to have celebrated the opening of its new corporate headquarters at Union Prairie Business Park Friday, June 9 from 11 a.m. to 6 p.m. The new building is located at 11815 N.E. 113th St. in Vancouver.
The $8 million, 23,200-square-foot corporate headquarters anchors the new three-phase business park. Union Prairie includes two tenant lease spaces of 4,000 and 6,600 square feet. The subsequent phases are planned for 25,300 square feet and 30,250 square feet respectively, and will be built as demand increases.
Approximately 45 New Tradition Homes employees will work out of the new building.
Team Construction was the contractor on the project.
The light industrial Heritage Centre building has opened in the Woodland Industrial Park. The building, which is owned by Heritage Centre LLC, is located at 1625 Heritage St. in Woodland. Schlecht Construction served as the general contractor. The building's grand opening was to be Thursday, June 8.
The $3.8 million facility has already attracted three tenants – Design Manufacturing, a commercial cabinetry shop previously located in Clark County; American Paper Converting, which stores large paper rolls used to make toilet tissue and paper towels at a plant adjacent to Heritage Centre; and Advanced Nutrients, a manufacturer of soil nutrients. The three companies have leased approximately three-fourths of the building's 65,000 square feet of space.
Schlecht expects the remaining space to be filled soon, particularly with high lease prices in the Portland-Vancouver area and sales tax advantages on capital improvements and for new hires in for manufacturers in Cowlitz County. Heritage Centre LLC plans to build a similar facility in the Woodland area in 2007.