text:
Disrupted-in-Schizophrenia-1 (DISC1): A key susceptibility factor for major mental illnesses
Naoya Sawamura*, Akira Sawa
ナノ・ライフ創新研究機構
Here we overview Disrupted-in-Schizophrenia-1 (DISC1), a promising lead in studying the pathophysiology of major mental conditions. Genetic association studies reproducibly suggest involvement of DISC1 in both schizophrenia and bipolar disorder in several ethnic groups. Different from several other susceptibility genes for schizophrenia, such as neuregulin-1 and dysbindin, there are two independent pedigrees in which genetic variations of DISC1 directly segregate with major mental conditions. This uniqueness has facilitated neurobiology of DISC1, which may hopefully lead to an important breakthrough in understanding of pathophysiology of major mental conditions. DISC1 is a multifunctional protein that plays a role in neurodevelopment and cell signaling. In autopsied brains from patients with psychosis and substance abuse, change in subcellular distribution of DISC1 is observed. DISC1 interacts with phosphodiesterase (PDE) 4B that degrades cyclic AMP (cAMP), which may be a regulatory molecule for working memory in the prefrontal cortex. Knockdown expression of DISC1 in developing cerebral cortex in mouse brains leads to changes that resemble, at least in part, the pathology found in patients with schizophrenia. These results support involvement of DISC1 in the pathophysiology of major mental conditions, including schizophrenia, in several mechanisms.
Integrated Molecular Medicine for Neuronal and Neoplastic Disorders
Blackwell Publishing Inc.
https://doi.org/10.1196/annals.1377.018
ISSN(印刷版)
ISSN(電子版)
神経科学(全般)
生化学、遺伝学、分子生物学(全般)
科学史および科学哲学
10.1196/annals.1377.018
「Disrupted-in-Schizophrenia-1 (DISC1): A key susceptibility factor for major mental illnesses」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。
Schizophrenia Arts & Humanities 100%
Susceptibility Arts & Humanities 78%
Mental Illness Arts & Humanities 66%
Disorder Chemical Compounds 57%
Molecule Chemical Compounds 23%
Bipolar Disorder Arts & Humanities 9%
Dysbindin Medicine & Life Sciences 8%
Sawamura, N., & Sawa, A. (2006). Disrupted-in-Schizophrenia-1 (DISC1): A key susceptibility factor for major mental illnesses. In Integrated Molecular Medicine for Neuronal and Neoplastic Disorders (pp. 126-133). (Annals of the New York Academy of Sciences; Vol. 1086). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1377.018
Disrupted-in-Schizophrenia-1 (DISC1) : A key susceptibility factor for major mental illnesses. / Sawamura, Naoya; Sawa, Akira.
Integrated Molecular Medicine for Neuronal and Neoplastic Disorders. Blackwell Publishing Inc., 2006. p. 126-133 (Annals of the New York Academy of Sciences; Vol. 1086).
Sawamura, N & Sawa, A 2006, Disrupted-in-Schizophrenia-1 (DISC1): A key susceptibility factor for major mental illnesses. in Integrated Molecular Medicine for Neuronal and Neoplastic Disorders. Annals of the New York Academy of Sciences, vol. 1086, Blackwell Publishing Inc., pp. 126-133. https://doi.org/10.1196/annals.1377.018
Sawamura N, Sawa A. Disrupted-in-Schizophrenia-1 (DISC1): A key susceptibility factor for major mental illnesses. In Integrated Molecular Medicine for Neuronal and Neoplastic Disorders. Blackwell Publishing Inc. 2006. p. 126-133. (Annals of the New York Academy of Sciences). doi: 10.1196/annals.1377.018
Sawamura, Naoya ; Sawa, Akira. / Disrupted-in-Schizophrenia-1 (DISC1) : A key susceptibility factor for major mental illnesses. Integrated Molecular Medicine for Neuronal and Neoplastic Disorders. Blackwell Publishing Inc., 2006. pp. 126-133 (Annals of the New York Academy of Sciences).
@inproceedings{460ed18324d74172ac3da7ab1c0e7ab6,
title = "Disrupted-in-Schizophrenia-1 (DISC1): A key susceptibility factor for major mental illnesses",
abstract = "Here we overview Disrupted-in-Schizophrenia-1 (DISC1), a promising lead in studying the pathophysiology of major mental conditions. Genetic association studies reproducibly suggest involvement of DISC1 in both schizophrenia and bipolar disorder in several ethnic groups. Different from several other susceptibility genes for schizophrenia, such as neuregulin-1 and dysbindin, there are two independent pedigrees in which genetic variations of DISC1 directly segregate with major mental conditions. This uniqueness has facilitated neurobiology of DISC1, which may hopefully lead to an important breakthrough in understanding of pathophysiology of major mental conditions. DISC1 is a multifunctional protein that plays a role in neurodevelopment and cell signaling. In autopsied brains from patients with psychosis and substance abuse, change in subcellular distribution of DISC1 is observed. DISC1 interacts with phosphodiesterase (PDE) 4B that degrades cyclic AMP (cAMP), which may be a regulatory molecule for working memory in the prefrontal cortex. Knockdown expression of DISC1 in developing cerebral cortex in mouse brains leads to changes that resemble, at least in part, the pathology found in patients with schizophrenia. These results support involvement of DISC1 in the pathophysiology of major mental conditions, including schizophrenia, in several mechanisms.",
keywords = "Bipolar disorder, DISC1, Schizophrenia",
author = "Naoya Sawamura and Akira Sawa",
doi = "10.1196/annals.1377.018",
series = "Annals of the New York Academy of Sciences",
publisher = "Blackwell Publishing Inc.",
booktitle = "Integrated Molecular Medicine for Neuronal and Neoplastic Disorders",
T1 - Disrupted-in-Schizophrenia-1 (DISC1)
T2 - A key susceptibility factor for major mental illnesses
AU - Sawamura, Naoya
AU - Sawa, Akira
N2 - Here we overview Disrupted-in-Schizophrenia-1 (DISC1), a promising lead in studying the pathophysiology of major mental conditions. Genetic association studies reproducibly suggest involvement of DISC1 in both schizophrenia and bipolar disorder in several ethnic groups. Different from several other susceptibility genes for schizophrenia, such as neuregulin-1 and dysbindin, there are two independent pedigrees in which genetic variations of DISC1 directly segregate with major mental conditions. This uniqueness has facilitated neurobiology of DISC1, which may hopefully lead to an important breakthrough in understanding of pathophysiology of major mental conditions. DISC1 is a multifunctional protein that plays a role in neurodevelopment and cell signaling. In autopsied brains from patients with psychosis and substance abuse, change in subcellular distribution of DISC1 is observed. DISC1 interacts with phosphodiesterase (PDE) 4B that degrades cyclic AMP (cAMP), which may be a regulatory molecule for working memory in the prefrontal cortex. Knockdown expression of DISC1 in developing cerebral cortex in mouse brains leads to changes that resemble, at least in part, the pathology found in patients with schizophrenia. These results support involvement of DISC1 in the pathophysiology of major mental conditions, including schizophrenia, in several mechanisms.
AB - Here we overview Disrupted-in-Schizophrenia-1 (DISC1), a promising lead in studying the pathophysiology of major mental conditions. Genetic association studies reproducibly suggest involvement of DISC1 in both schizophrenia and bipolar disorder in several ethnic groups. Different from several other susceptibility genes for schizophrenia, such as neuregulin-1 and dysbindin, there are two independent pedigrees in which genetic variations of DISC1 directly segregate with major mental conditions. This uniqueness has facilitated neurobiology of DISC1, which may hopefully lead to an important breakthrough in understanding of pathophysiology of major mental conditions. DISC1 is a multifunctional protein that plays a role in neurodevelopment and cell signaling. In autopsied brains from patients with psychosis and substance abuse, change in subcellular distribution of DISC1 is observed. DISC1 interacts with phosphodiesterase (PDE) 4B that degrades cyclic AMP (cAMP), which may be a regulatory molecule for working memory in the prefrontal cortex. Knockdown expression of DISC1 in developing cerebral cortex in mouse brains leads to changes that resemble, at least in part, the pathology found in patients with schizophrenia. These results support involvement of DISC1 in the pathophysiology of major mental conditions, including schizophrenia, in several mechanisms.
KW - Bipolar disorder
KW - DISC1
KW - Schizophrenia
U2 - 10.1196/annals.1377.018
DO - 10.1196/annals.1377.018
T3 - Annals of the New York Academy of Sciences
BT - Integrated Molecular Medicine for Neuronal and Neoplastic Disorders
PB - Blackwell Publishing Inc.


Includes: Sub Sandwiches on Freshly Baked Sub Buns, Bag of Potato Chips, and Your Choice of 12oz. Can of Pop or 12oz. Bottled Water, Utensils, Appropriate Condiments, and Napkins.
FREE Delivery to Campus on Boxed Lunch Orders That Don't Require the Use of a Vehicle.
Includes: Sandwich, Wrap or Salad of Your Choice, Bag of Potato Chips, Freshly Baked Cookie (Chef's Choice), and Your Choice of 12oz. Can of Pop or 12oz. Bottled Water, Utensils, Appropriate Condiments, and Napkins $10.00 Each $12.50 Each with Fresh Fruit Cup. We must ask that you limit your choices to these varieties, thank you.


Dragon Soul Alchemy BOT/Drachensteinalchemie BOT. Best Way to get YANG.
When we release it first, you will need to have completed the first two quests from the alchemist manually, but this might change in the future.
Also, refining wont be automatically done at first.
Thanks for korona778 for his help here.
Finnaly our friend, you are our hero, thanks for making all the hard work for us, il always pay m2bob rather that gameforge, lots of regards and looking forward to this feature !
Post was edited 2 times, last by "korona778" ( Jul 4th 2018, 10:56pm ).
Naja es gibt ja Theoretisch die Möglichkeit das so laufen zu lassen also mit dem Account Manager das man einfach quasi 5 Accounts a 6 Chars, man kann bei m2Bob Maximal 30 Stück eintragen immer halt mit einem anderen Char Slot also es würde ja Theoretisch Funktionieren mit umwegen sehe Ich das richtig ?
Haha ach 6 Accounts a 5 Chars, ich schätze mal man braucht pro Char auch nur ne Stunde c.A ?
Big thanks Korona and Slait!!
Right. Better way is 6accs x 5chars to farm dragon soul.
I dont know how about you, but for me its not worth to farm 3 ds each acc daily.
As Korona said in first post, "90 cor draconis daily"
Prinzipiell gesehen wäre es natürlich bequemer, wenn man dann noch einstellen könnte ob man danach den Char wechseln möchte. Im Prinzip vermute ich, dass solche Alchi chars nicht mehr auffallen als andere. Sind im Schnitt 1 Std am Tag online, da schätze ich die Risiken als sehr gering ein. Wenn man täglich mit jeweils einem Account bzw. einem Char seine Cors farmt, hat man recht langsam "Ergebnisse". Vorteilhafter wäre es dennoch, wenn man eben am Tag seine 15 Cors macht, selbstverständlich bin ich dir schon mal zu großem Dank verpflichtet, steht außer Frage.
Nichts desto trotz, die Funktion wäre auf jeden Fall seeehr nützlich. Wenn das noch machbar wäre, wäre das wirklich top!
Die Funktion ist doch schon eingebaut worden, außerdem ist das mit mehreren Charakteren auf einem Account gar kein Problem. Man muss halt pro Charakter einen Slot belegen. Habe beispielsweise 6 Accounts mit 5 Charakteren, diese belegen insgesamt 30 Slots und wechseln, wenn der erste fertig ist.
To everyone who don't know how effectively use this bot. This whole script was created mainly for system 6 accounts per 5 character each. Then you will be able to get daily 90 dragon cores. I made a small presentation about that.
but we cant do it, cuz we dont have "enter char" in start/stop manager.
But still thats amazing, thanks!
First slot of group 1-6 will start at 00:00 and next of them will be switching after collected 3 cores, then after all group finnish, next one (7-12) will start at 5:30 with the same setting etc.
Post was edited 1 time, last by "korona778" ( Jul 11th 2018, 11:09am ).
Will it automaticaly switch characters?
Because for me, "slot" mean account.
"Exit bot after 3 dragon cores have been collected"
So if i start with character 0 - it will switch to character 1 after collect 3dc, or it will close the bot??
24 hours = 24 accounts(120 chars, 3dc per char) = 360 dc daily.
Again my question is: "bot will exit bot or switch character"?
Start/Stop manager will simply close slot (for example slot 2) and if you set in there to start slot 3 after slot 2 he will close one and open another, so don't worry. I know what you mean, about closing bot, he only close that slot which finnished not all program. For now start/stop don't have option to concrete choose one character from each account, he is working on all accounts as a "slots". I will talk about that with @Slait .
Post was edited 4 times, last by "korona778" ( Jul 11th 2018, 11:34am ).
where is char 1,2, 3, 4 ???
I dont wanna close slot, i wanna switch character!
Pick up drop from party Members.


text:
You are here: Home » MEDIA » Books » Gemsigns (®Evolution Book 1) by Stephanie Saulter (book review)
Gemsigns (®Evolution Book 1) by Stephanie Saulter (book review)
October 15, 2015 | By VincaRussell	| Reply More
A few decades ago, thousands of young people were dying after a strange technological plague swept the world. Almost a whole generation was lost before scientists found a solution, a genetic modification that would prevent people from succumbing to the disease. The modification was also used to create specialised workers, Gems – identified by bright neon gemsigns such as coloured hair – to fill the labour gap left by losing so many. Now the plague has gone and the Gems are ready to take back their human rights, unwilling to continue to be slaves earning money only for the corporations that own them. The upcoming conference on Gem rights will determine their future but, as tensions mount and violent attacks start to occur, which way the decision will go remains unclear. Will the Gems earn their freedom or will the corporations retain ownership, dooming the Gems to lives of servitude?
It's been a long time since I've been captivated by the opening paragraph of a book, but from the very first page of Stephanie Saulter's 'Gemsigns', I was completely hooked. The language is very precise and tells you exactly what you need to know, painting a vividly realised world without ever straying into the territory of lengthy exposition. I really enjoyed reading it.
The theme of this book is largely political and we follow Dr. Eli Walker, an anthropologist who has been given the task of assessing the human behaviours of the Gems. How they socialise and interact with others, whether they display 'normal' human behaviours, if there's anything other than physical characteristics of the bright hair and modified attributes that suggests they are anything other than 'human'. It's a really interesting process to follow, journeying with him as he meets representatives from the big corporations and people from the Gem communities, preparing to deliver his findings to the conference on Gem rights. You very soon start questioning what it means to be human and the story makes you think long and hard about the way in which we, as both individuals and a society, behave on a day to day basis. There's plenty of material in here to ponder and that's part of the reason it's so enjoyable to read.
Of course, a non-fiction treatise on behaviours could achieve that kind of thought-provoking response, but this is a novel so there needs to be something more to it than a set of interesting intellectual ideas. I have no hesitation in saying that it certainly delivers on all the other fronts, too, from wonderful characters to detailed world-building and a neat network of sub-plots that combine to make a great story. The action only takes place over a week – an unusually short time frame for Science Fiction but it packs a lot into that time and in fact makes you focus on the little details, which turn out to be plentiful!
Eli is an interesting chap on his own, but when you put him together with the enigmatic Aryel Morningstar, the Gems' appointed leader, the pair really come alive. They interact beautifully and so realistically that it feels like you're in the room with them. The community of Gems, the troubles they're facing and the prejudices they work so hard to overcome was quite touching at times and at other points was distressing. There are many similarities with the prejudices and struggles still faced by many minorities in today's society, Saulter just takes these issues and transplants them very well into a future Earth.
In case you've not already guessed, I got through 'Gemsigns' pretty quickly, reluctant to put it down before I'd found out how everything turned out. It was a bit like avidly following a news story, but with more moments of hope and compassion brought to the front amid all the violence and oppression. 'Gemsigns' was a very impressive debut novel and a thoroughly engaging read that's left me eager to read the sequel.
(pub: Jo Fletcher Books/Quercus, 2014. 339 page hardback. Price: $26.99 (UK), £10.69 (UK). ISBN: 978-1-62365-160-2)
check out website: www.quercusbooks.co.uk
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redpajama_set_name: RedPajamaCommonCrawl


Mechanics of Materials, Part I.
we're going to look at stresses on inclined planes.
the case of plane stress.
stresses on inclined planes in general.
the stress distribution will approach uniformity.
So here's a graphic of that cube.
this state of stress at a point in their positive directions.
we'll come up with the case of plane stress.
shear stresses on an inclined plane for uniaxial loading for an angle theta.
We found out that the max normal stress occurs at an angle of 0 or 180 degrees.
The max shear stress occurs at an angle of 45 or 135 degrees.
the shear stress and the shear force vector changed directions.
was equal to 2 times the magnitude of the maximum shear stress.
normal stress on an arbitrary plane, at an angle theta.
we were able to draw what we called shear force and bending moment diagrams.
But I have a structure, a beam, with different types of vertical loads.
find the internal forces acting on an infinitesimally small part.
I could go ahead and have a certain type of loading, I could make a cut.
the normal stresses and the shear stresses, from the external loading.
the normal stresses are on an arbitrary plane.
shear stress occur, because we wanna make sure we avoid failure.
And I have a part here.
This is a piston with a connecting rod.
that one of our teams here at Georgia Tech built.
But you can see that there is a failure.
normal stresses are on various planes to make sure that we avoid failures.
And so here, again, I take a cut on an inclined plane.
the inclined plane in the normal and the tangential direction.
And, we'll go ahead, and I show the stresses here.
The sign convention will be the same as what we have used before.
Normal stress will be positive in tension or negative in compression.
Shear stress is positive if it is in the positive direction of the coordinate axis.
the positive tangential direction is the definitions of our positive shear stress.
taken as positive from the reference x axis.
the stresses on incline planes next module.


The 2015 Namibia-Finland Logistic Seminar, held in Walvis Bay on 20-22 October, has been themed and focused on exploring the economic potential between South and North. The seminar agenda was drawn up to target the development of cooperation and capacity-building between the maritime clusters of Namibia and Finland. The event was organised by Satakunta University of Applied Sciences in Finland (SAMK) in close cooperation with the Polytechnic of Namibia (PoN), the Namibian–German Centre for Logistics (NGCL), the Namibia Fisheries and Maritime Institute (NAMFI), the Embassy of Finland in Windhoek and the Walvis Bay Corridor Group.
The seminar is part of the Finnish-funded MARIBIA project activities, which has been instituted to improve maritime training in Namibia. MARIBIA is based around work undertaken by NAMFI, PoN and SAMK. Supporting partners include the Ministry of Fisheries and Marine Resources of Namibia (MFMR), the Directorate of Maritime Affairs within Namibia's Ministry of Works and Transport (DMA), the Harbour of the Walvis Bay of Namibia (NAMPORT), and the European Maritime Safety Agency (EMSA).
The three agenceis are jointly promoting education, development and enhancement of maritime education-based curricula, programmes, educational and administrative processes.They are also focused on building the capacity of the educational and administrative staff through sustainable structures and training initiatives.The over-arching ojective is the promotion of the creation and preservation of sustainable career opportunities in the maritime field. In the long-term, the aim is for work towards improving maritime education in Namibia, in the form of the new curricula adopted by NAMFI and PoN, to be approved by the International Maritime Organisation (IMO).
Key personnel involved in achieving the goals and executing the initiatives presented in Walvis Bay in October include Captain Heikki Koivisto of SAMK, Dean Dr Samuel John of PoN, Captain David Hamupembe of NAMFI, and Riitta Tempakka of SAMK.


text:
Q: Windows container with ACI - network access problem I have windows container running in ACI with public address but with specific TCP port - 7070.
I've set it with following command:
az container create --name xxxxxx --resource-group xxxxx --image xxxxx.azurecr.io/xxxxx:yyy --registry-login-server xxxxxx --registry-username xxxxxx --dns-name-label xxxxxxx --command-line xxxxx --os-type Windows --registry-password xxxxx --ports 7070 --protocol TCP --ip-address Public

It runs ok as far as I can tell, but I cannot access application listening on 7070 port.
> telnet xxxxxx 7070
Connecting To xxxxx...Could not open connection to the host, on port 7070: Connect failed

Obviously when running locally (Docker for Windows) it works smoothly.
What can I do here ?
I assume there might be some security/firewall on public IP level, but public IP that my container was given is not available for me to manage - at least my azure portal "Public IP addresses" service is not showing it.
Any suggestion/idea where to search for solution?

A: It looks like your ACI has not propagated well. You could try to deploy it again after a while. Possibly, the port 7070 is forbidden on your current machine or local network where you are telneting from. You might check some security/firewall on your on-premise network.

A: It seems like ACI ports work only for HTTP "alike" connections.
I've tried multiple ports with just TCP sockets to no luck, but as soon as I've setup http server - all works smoothly.
So at least for me ACI with windows containers is useless.

redpajama_set_name: RedPajamaStackExchange


Traditionally liberal, American Jews are becoming steadily more conservative.
I've always considered it self-evident that Judaism is most at home with conservatism, both as a worldview and as a modern political movement.
Conservatives value tradition as a time-tested repository of human experience.
To me, all this sounds pretty compatible with Judaism. The normative Jewish political tradition, as outlined by the ancient rabbis in the Talmud, warns against anarchy and chaos, but also against excessive trust in government; stresses that deeds are more consequential than theory, and that the fulfillment of God's teaching is inextricably entwined with the duty to take care of earthly fundamentals; posits tradition as non-negotiable and yet is ready to amend and adapt many parts of the Torah for pragmatic reasons; and, while never relinquishing the Jewish people's right to the land of Israel, takes into account the role of what we would now call international law.
In many countries, Jews did eventually turn leftward—but often less as a matter of choice than in response to Gentile attitudes and conduct: parties of the right were less welcoming than parties of the left. Dire economic conditions also rendered the growing Jewish proletariat susceptible to the lure of socialist utopianism. Later, as Jews began to climb socially through access to the professions, many tended to adopt modernist or "progressive" attitudes. The rise of Nazism, followed by World War II and the Holocaust, solidified the Jewish attachment to liberal democracy, further confirmed by the birth of Israel in 1948.
But the left moment in Jewish history could not last. Global prosperity gradually extinguished most Jewish poverty in the West, and with it much Jewish social utopianism. Communism, in the form mainly of the Soviet Union, proved radically inhospitable to Jews and implacably opposed to Israel. Eventually, social democrats and liberals would also distance themselves from Zionism, Israel, and even the Jews, dealing a further blow to previous generations' illusions.
The majority of Jews in Israel, France, and Britain vote for conservative parties.
As of today, the majority of Jews in Israel, France, and Britain vote for conservative parties. Even in the U.S., a conservative minority has been growing in numbers and influence. Although two out of three American Jews still define themselves as liberals rather than conservatives, and tend to support, no matter what, the Democrats over the Republicans, there are signs that things may be changing even in this respect. When it comes to Israel's survival and security, everyone knows that Republicans are now the friendlier of America's two parties.
The moment, in other words, is ripe for an infusion of "the spirit of Jewish conservatism"—perhaps even riper than Eric Cohen imagines. What does it signify, after all, when a conservative Israeli prime minister is invited repeatedly to address the U.S. Congress on the most vital issues affecting both the Jewish state and the entire democratic West, and is received with overflowing warmth and applause? The answer is blowing in the wind.


text:
"""
    buildthedocs.sources
    Definition of default source providers

    Copyright (c) 2015 Pietro Albini
    Licensed under MIT license
"""

import os
import urllib.request
import shutil
import subprocess

def obtain_git(config, dest):
    """ Obtain the source code from a git repository """
    subprocess.call(["git", "clone", config["source"]["url"], dest, "-q"])
    subprocess.call(["git", "--git-dir="+dest+"/.git", "--work-tree="+dest,
                     "checkout", config["source"]["checkout"], "-q"])

def obtain_url(config, dest):
    """ Obtain the source code from an HTTP url """
    # Download the archive
    archive_dest = os.path.join(dest, '__temp_download__')
    urllib.request.urlretrieve(config["source"]["url"], archive_dest)

    # Extract the archive and remove it
    shutil.unpack_archive(archive_dest, dest, config["source"]["compression"])
    os.unlink(archive_dest)

def obtain_local(config, dest):
    """ Obtain the source from the local filesystem """
    shutil.copytree(config["source"]["path"], dest)

redpajama_set_name: RedPajamaGithub


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Jocelyn BUISSON, Stéphane GALLAND, Nicolas GAUD, Mikaël GONÇALVES, Abderrafiaa KOUKAM. "Real-time Collision Avoidance for Pedestrian and Bicyclist Simulation: a smooth and predictive approach." In Proc. of 2nd International Workshop on Agent-based Mobility, Traffic and Transportation Models, Methodologies and Applications (ABMTRANS13), Ansar-Ul-Haque YASAR, Luk KNAPEN (eds.), pp. 815-820, Halifax, Nova Scotia, Canada, Elsevier, Best Paper Award, 2013. DOI: 10.1016/j.procs.2013.06.108.


text:
WLWT - Cincinnati
Hamilton woman turns 103 years old, now having lived through two pandemics
WLWT News 5 shares a heartwarming story of a Hamilton County woman who has lived more than a century.
Republican lawmaker to ask Justice Department to investigate Trump's response to attack on U.S. Capitol
A ranking House Republican is formally asking the Justice Department to broaden its investigation to include President Trump's conduct during the Jan. 6 attack on the U.S. Capitol.
Guatemalan soldiers blocked part of a caravan of as many as 9,000 Honduran migrants Saturday at a point not far from where they entered the country seeking to reach the U.S. border. The soldiers, many wearing helmets and wielding shields and sticks, formed ranks across a highway in Chiquimula, near the Honduras border, to block the procession of migrants. Guatemala's immigration agency distributed a video showing a couple of hundred men scuffling with soldiers, pushing and running through their lines, even as troops held hundreds more back.
Guatemalan security forces on Sunday used sticks and tear gas to beat back a large migrant caravan bound for the United States, just days before the advent of a new U.S. administration, which urged travelers to abandon the journey. Between 7,000 and 8,000 migrants, including families with young children, have entered Guatemala since Friday, authorities say, fleeing poverty and violence in a region hammered by the coronavirus pandemic and back-to-back hurricanes in November. A large section of the caravan clashed on a road early on Sunday with Guatemalan security officials, some 3,000 of whom had mustered by the village of Vado Hondo, about 55 km (34 miles) from the borders of Honduras and El Salvador.


text:
Education Writers Association
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Supreme Court Rules on Public Money for Religious Schools
Case challenges Blaine Amendments, separation of church and state in school choice programs
January 22, 2020 Emily Richmond
Editor's note: This post was updated on June 30, 2020, after the Supreme Court ruled in the Espinoza v. Montana Department of Revenue case.
The U.S. Supreme Court today ruled that Montana unconstitutionally prevented public dollars from following students to private schools — potentially creating a landmark decision on the separation of church and state in public education. (Read the full opinion here.)
The justices heard arguments Jan. 22 in Espinoza v. Montana Department of Revenue. As Education Week's Evie Blad summed it up, "The case has been closely watched by advocates who hope to expand the use of publicly funded voucher and tax-credit scholarships. And it's being watched by education groups that oppose such programs, fearing they will siphon away tax dollars that would be better spent on public schools."
Thirty-seven states — including Montana — have added so-called "Blaine Amendments" to their constitutions, prohibiting public dollars from going directly to religious institutions. In some states, programs like tax-credit scholarships have been set up to circumvent Blaine Amendments. In those instances, money that would have otherwise gone to public coffers is redirected to cover students' costs at private or parochial schools.
That was the premise of the case decided this week by the Supreme Court. Among the questions justices raised during oral arguments: Who's the "affected party" if states aren't allowed to use tax-credit scholarships? Is it the parents seeking a religious school for their kids, the parochial schools who benefit from the funding, or the taxpayers who want to see their dollars used for that purpose?
In 2015, Montana passed a law allowing tax credits for individuals who donated to private school scholarship funds. The Montana Supreme Court struck down the law, arguing that it violates the separation of church and state. The plaintiff in the Supreme Court case is Kendra Espinoza, the mother of two children enrolled at a private Christian school who wanted the benefit of the scholarship program.
Potential Effects on School Choice
As NPR's Nina Totenberg explained, the Supreme Court decision on Espinoza "could dramatically alter the line separating church and state." The New York Times' Erica Green outlined the potential for a "watershed moment" in the nation's broader debate over school choice. And U.S. News & World Report's Lauren Camera framed the looming decision as having "seismic implications not just for states and their public school systems but also for the fate of the Trump administration's No.1 education priority: a $5 billion tax credit scholarship. It could also serve to cement the president in the good graces of his important evangelical Christian base ahead of the 2020 election, or not."
But don't expect a sudden flood of new voucher programs as a result of a decision in the plaintiff's favor, as reporting by Chalkbeat's Matt Barnum and Kalyn Belsha indicates. "States that wanted to have a voucher law have already adopted voucher laws," Kevin Welner, a professor at the University of Colorado who is critical of vouchers, told Chalkbeat. "Those horses are already out of the barn."
Local reporters — especially those living in one of the states with Blaine Amendments — can dig into this story by offering their readers and listeners a quick explainer of how the Supreme Court decision might impact school choice in their communities. Among the questions to ask: How many students are actually taking part in voucher and scholarship programs? Who are they, and what factors led those families to select private schools instead of enrolling in a local public school? Who's monitoring the academic progress of students who opt for scholarships and vouchers? In Indiana, as Chalkbeat reported, students in the state's voucher program who opted for private over public schools actually saw their test scores drop in math.
For more background, Education Week's Mark Walsh provides important historical context on prior Supreme Court rulings on religious school funding, and biographical tidbits about U.S. Rep. James G. Blaine of Maine, who introduced his failed amendment to Congress in 1875. EWA looked at tax credit scholarships and voucher programs at our 2017 National Seminar. You can read a writeup of that session here. U.S. Education Secretary Betsy DeVos discussed her support for a proposed $5 billion federally funded voucher program at EWA's 2019 National Seminar (she has a front-row seat for the Supreme Court arguments). And NPR's Cory Turner discusses his investigation into voucher programs in this 2017 episode of the EWA Radio podcast.
Have a question, comment or concern for the Educated Reporter? Contact Emily Richmond. Follow her on Twitter @EWAEmily.
Read other Educated Reporter articles.
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Emily Richmond
Emily Richmond is the public editor of the Education Writers Association. She coordinates programming and training opportunities for members and provides individualized reporting and writing help to journalists. She also hosts the EWA Radio podcast, and authors EWA's "The Educated Reporter" blog.
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Trump and DeVos Love School Choice. But Are Vouchers the Way To Go?
July 21, 2017 Sarah Butrymowicz of The Hechinger Report for EWA
Education reporters can expect to hear a lot more about school choice over the next four to eight years. U.S. Secretary of Education Betsy DeVos is a longtime choice advocate and has pledged that the Trump administration will do more to advance this cause than any other presidency.
While specifics are still in short supply on how the Trump administration's zeal for school choice will translate into new or expanded federal programs, it's a topic that will be hotly debated at the national, state and local levels.
What's Ahead for Private School Choice Policy in 2019?
Vouchers and voucher-like programs may grow in some states, face pushback elsewhere
January 8, 2019 Erik Robelen
Arizona voters in November gave a decisive thumbs down to a ballot measure that sought to expand a voucher-like program in that state. The same voters, however, opted by a wide margin to re-elect Republican Gov. Doug Ducey — a champion of private school choice who threw his support behind the failed referendum.
And so it goes. For education overall, the 2018 election outcomes revealed a case of seeming contradictions, as we reported right after the election.
NPR Digs Deep on School Vouchers
EWA Radio: Episode 125
June 5, 2017 Emily Richmond Subscribe to #ewaRADIO
Cory Turner discusses the NPR education team's deep dive into school vouchers, with a focus on Indiana, home to the largest voucher program in the nation. Among NPR's findings: less than 1 percent of participating students transferred out of public schools that had been labeled by the state as low performers, and many students using vouchers were already attending private schools. With school choice as a centerpiece to President Trump's education policy agenda, what does the evidence show when it comes to academic outcomes for students using vouchers?
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Home/RELEASES/PLS&TY Releases Summertime Anthem, "Ride or Die"
PLS&TY Releases Summertime Anthem, "Ride or Die"
This self-released track is out now
Hasan Singh Send an email July 11, 2021
Florida native PLS&TY teams up with LA-based Barbados-born singer/songwriter Bobby Saint for the new collaboration, "Ride or Die". It's a feel-good summertime anthem that will transport you to being on vacation with your one and only. Featuring groovy but gentle melodies from PLS&TY and Saint's heartfelt, wide vocal talents, "Ride or Die" is a song you'll want to play over and over again this season; accordingly, it embodies love, positivity, and connection, all of which form the fabric of the beautiful human experience. This is what PLS&TY had to say about the inspiration behind the new release:
"'Ride or Die' is a summertime, feel-good single that encompasses love & romance. Bobby Saint's vocals lead listeners to imagine time spent in tropical paradise with their partner. Together, Bobby Saint and I created a song that transmits the ethos of the PLS&TY brand: good vibes and good times. Enjoy."
Tommy Leas, a Florida native, better known as PLS&TY, is burgeoning into the electronic dance music scene. His style is an energetic mix of languid bass, captivating vocals, and upbeat melodies to make anybody feel good. Also, his productions have been remixed by Morgan Page, Rusko, Cazzette, Bondax, YehMe2 (Josh from Flosstradamus latest venture), and more. These are in addition to his chart-topping singles, "Good Vibes," "Down For Me," "Rebel Love," and "Motives". Additionally, PLS&TY's remix of Genevieve's "Colors" was featured in a Hershey's chocolate television commercial that has amassed over 1 billion views. Now in 2021, PLS&TY shows no signs of slowing down, off the heels of a 2019 touring season which included A-List festivals Shaky Beats, Breakaway, Electric Forest, EDC Las Vegas, & more. PLS&TY's "Ride or Die" featuring Bobby Saint is out now.
Bobby Saint Bondax breakaway CAZZETTE EDC Las Vegas electric forest FLORIDA Genevieve Morgan Page pls&ty Rusko Shaky Beats Summer track yehme2
Tim van Werd Teams Up with Crime Zcene for "On Your Side"
CRSSD Festival Will Return to Waterfront Park in San Diego


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Q: Application Context Menu in WPF with WindowStyle=None I've got a very strange problem with a custom WPF window. The window is designed completely in WPF with WindowStyle=None and ResizeMode=NoResize. So I have to reimplement all the basic window handling stuff like moving, resizing and - here is the problem - the application context menu.
Currently I'm calling the context menu in the mouse-event of the app icon and application titlebar as follows:
POINT point=new POINT();
GetCursorPos(out point);
IntPtr handle=GetSystemMenu(new WindowInteropHelper(this).Handle, false);
IntPtr hd=new WindowInteropHelper(this).Handle;
int retvalue=TrackPopupMenu(handle, TPM_RETURNCMD, (int)point.X, (int)point.Y, 0, hd, new IntPtr());
PostMessage(hd, WM_SYSCOMMAND, retvalue, 0);

This is a code snipped you can find all over the net, looks like everyone is doing it this way.
However depending on the events I use to show the menu the following happens:
MouseUp:

*

*Right click on titlebar/app icon: Application context menu appears

*Doing another right click without moving the mouse: Somehow a right click event is generated inside the window (while the mouse still points on the titlebar).

Funny part: The Click is translated into the window by window.Left and window.Top. If I place the window correctly, I can open the context menu of a ListView inside of the window while the mouse still points to the tilebar.
MouseDown:

*

*Right mouse down on titlebar/app icon: Application context menu appears

*Right mouse up without moving the mouse: Same behaviour, a right click is generated inside of the window at Mouse position + window.Left/window.Top.

I've made a screenshot and measured the pixel distance to check if it's really window.Top/Left.
That's what I've done while trying to solve the problem:

*

*Tested dozens of changes to the Code snipped to show the context menu without effect

*I completely removed resize/move code from the window class, no change

*Played around with EventArgs.Handled, no change

*Enqueued the code snipped in the dispatcher instead of calling it directly in the event, no change

A: Have you already tried to implement the context menu in the xaml of the custom window? If you are working with Templates you can already integrate it on there or use it in the CustomWindow.xaml
<'ControlName'.ContextMenu>
    <ContextMenu>
        <MenuItem Header="FooRoot">
            <MenuItem Header="Foo" Command="{Binding FooCommand}"/>
        </MenuItem>
        <MenuItem Header="Foo2" Click="OnClick"/>
    </ContextMenu>
</'ControlName'.ContextMenu>

You can bind the command (maybe if you are working the the MVVM pattern) or make an event for it.