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LAW OFFICE OF PETER D. FENZEL (845) 848-2992
368 Western Highway Tappan, NY 10983
Trusted counselor and advisor
for life's transitions.
These practice areas are more a guide to our legal services than separate disciplines. Many overlap. For example, Trust strategies can be helpful to plan your estate; to draft your will; to secure care for the elderly, for special needs children, and for others who lack the capacity to care for themselves; and to protect assets when creating or selling a business.
Please take a few moments to explore our practice areas. See how we may be the solution for your legal needs.
BUSINESS FORMATION & SUCCESSION
Few endeavors have so great a potential to impact people's lives for the better as the practice of law.
We see our practice as one which celebrates human dignity, not just for the great and the vigorous, but for the aged, the infirm, the afflicted, the ordinary people who meet life's challenges with courage and hope. At the Law Office of Peter D. Fenzel we are here to empower you, and those you love, to live the life you choose for yourselves.
We are here to empower you to provide care for your elderly loved ones, so that they may enjoy the best quality of life for as long as they live. We are here to empower you to provide care for your special needs child, so that they may reach their full potential and live a happy, fulfilling life. We are here to empower you to endow future generations with the fruits of your love and the bounty of your labors. We are here to empower you to enjoy your rights to equal protection under the law.
It is within your power now to take the first step.
The Law Office of Peter D. Fenzel is conveniently located at 368 Western Highway in Tappan, NY in Rockland County, easily accessible from the Palisades Interstate Parkway and the New York State Thruway. We are only 15 minutes from the Tappan Zee Bridge and Westchester County, and only 20 minutes from the George Washington Bridge and New York City. Our firm services the legal needs of individuals, families, and businesses in Rockland, Westchester, and Orange Counties, and in New York City.
ATTORNEY PRINCIPAL - PETER D. FENZEL
Peter was born in White Plains, NY and was raised in Eastchester, NY. He attended grammar school in Tuckahoe at Immaculate Conception School, and graduated from Archbishop Stepinac High School in White Plains in 1969. He earned his Bachelor's degree in History, with honors, from the College of the Holy Cross in Worcester, MA in 1973, and earned his Juris Doctor degree from the Fordham University School of Law in 1976.
Peter's early years in the law were spent as an associate, and then as a partner, in a commercial litigation law firm in lower Manhattan. In 1984 he started his own litigation and insurance law practice in Manhattan and in Newark, NJ. In 2008 Peter was recruited by the brokerage side of a large bank, where he served as a registered advisor certificated in Special Needs and Elder Care Planning. He served there for three years, before returning to his first love, the private practice of law.
Peter has to his credit many published legal decisions earned in the federal and state courts of New York and New Jersey on both trial and appellate levels. He has served with distinction in leadership capacities on many bar committees and associations. He is a member of the Rockland County Bar Association, the New York City Bar Association, and the New York State Bar Association, and seves on several bar committees on Trust and Estate Law, Elder Law, Special Needs Law, and litigation.
Peter is the father of five children, all grown, and so far one grandchild. He has served his community as a Cub Scout Cub Master, as a basketball coach, a soccer coach, a softball coach, and as president of his Rotary Club, among many other civic volunteer positions. He is a parishoner of the Church of the Presentation in Upper Saddle River, NJ, and is a member of the John A. Keogh Council Knights of Columbus in Tuckahoe.
Peter is the Director of Street 2 Street Preparatory Academy in Paterson, NJ, an after school tutoring program benefiting inner city children. He also is founder and president of Serviceman's Transitional Assistance Resources (STAR), providing defense and counsel to combat veterans carrying the hidden wounds of Post Traumatic Stress and Traumatic Brain Injury.
In his spare time Peter is a student of the Revolutionary War in Rockland, Orange, and Bergen Counties, and sings second tenor in the Orpheus Club Men's Chorus.
368 Western Highway, Tappan, NY 10983
pdfenzel@peterfenzellaw.com
Click Here for a Map to Find Us
LAW OFFICE OF PETER D. F ENZEL
For any general inquiries, please fill in the following contact form:
DISCLAIMER: The contents of this web site are for informational purposes only. They may not be considered or relied upon as legal advice. Neither the contents of this web site nor inquiries made on the above contact form may be construed to establish an attorney client relationship. The establishment of an attorney client relationship can only be done through a formal written letter of engagement signed by both the client and by Mr. Fenzel.
© 2016 by Peter D. Fenzel, Esq. Created with Wix.com


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In this work, the results of investigations of manufacturing ceramic materials on the basis of Ti, B, C and N containing systems are presented. The nanocrystalline ceramics were synthesized using a non-hydrolytic sol-gel method. The process was carried out in two stages. In the first low-temperature stage the precursor was obtained. The synthesis of ceramic phases, however, was conducted in the second high-temperature stage, in an argon atmosphere. Depending on the initial composition of the mixtures, the temperature and the time, the following products were obtained: TiCx, TiCxN1−x, TiB2 and B4C. The course of the process was investigated by thermogravimetric and differential scanning calorimetry methods (TG-DSC) coupled with mass spectrometry (MS). The solid state products were identified with use of X-ray diffraction (XRD). The size of the crystallites was estimated by the Scherrer method. The structure and morphology images of nanocrystalline powders were obtained using scanning electron microscopy (SEM) and transmission electron microscopy (TEM).


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Athens's Contemporary Art Scene Grows and More: Morning Links from September 4, 2020
To receive Morning Links in your inbox every weekday, sign up for our Breakfast with ARTnews newsletter.
The Everson Museum of Art in Syracuse New York will deaccession Jackson Pollock's 1946 painting Red Composition, which is valued between $12 million and $18 million, as part of an effort to diversify its collection. [Art Market Monitor]
Following a pause due to the pandemic, a New York residency for Russian artists is planning for its fall cycle. The initiative was organized in a collaboration between the Moscow-based art collective AES+F and the International Studio & Curatorial Program. [The Art Newspaper]
The contemporary art scene in Athens is flourishing, according to a new report by the Financial Times. [Financial Times]
Vanity Fair has a piece on the U.S. Senate Intelligence Committee's 2018 deposition of Leon Black, who has appeared on ARTnews's … Read the rest
Mary Weatherford Revisits a 1957 ARTnews Profile of Painter Joan Mitchell
In 1957, art critic Irving Sandler paid a visit to the studio of painter Joan Mitchell, an Abstract Expressionist known for her brushy images capturing nature. The result of that visit, printed in the October 1957 issue of ARTnews, became one of the most famous essays in this magazine's "Paints a Picture" series, in which an artist illuminates the process behind one of his or her artworks. With an upcoming traveling retrospective of Mitchell's work at the Baltimore Museum of Art in mind, ARTnews enlisted Mary Weatherford, an artist who has spoken of being inspired by Mitchell, to discuss Sandler's article. "He's a beautiful writer, so clear, so easy to read," Weatherford said of Sandler's writing. "I want to be the equivalent when I'm talking about this."
Irving Sandler on Joan Mitchell: She finds particularly distasteful moral insinuations concerning "good" versus "bad" criteria, and insists that … Read the rest
Translucent Sculptures of Segmented Glass by Artist Jiyong Lee Evoke Single-Celled Organisms
"Green Cosmarium Segmentation" (2018), hot sculpted, cut, color laminated, carved, glass, 7 1/4 × 10 × 7 1/4 inches. All images © Jiyong Lee, shared with permission
Fascinated by the organisms found in the sea and bodies of freshwater, artist Jiyong Lee (previously) sculpts semi-transparent artworks that evoke the various forms of algae and other microscopic creatures. The segmented pieces, which are composed of smooth, matte glass, create both organic and geometric shapes. Part of an ongoing Segmentation Series, the composite works consider the evolution of a single cell, which Lee expands on:
I work with glass that has transparency and translucency, two qualities that serve as perfect metaphors for what is known and unknown about life science. The segmented, geometrical forms of my work represent cells, embryos, biological and molecular structures—each symbolizing the building blocks of life as well as the starting point of life.
Lee … Read the rest
Tate and Anthony d'Offay, Dealer Accused of Sexual Harassment, Terminate Relationship
The Tate museum network in England said it has cut ties with Anthony d'Offay, a dealer who was accused of sexual harassment by multiple women in 2018. The museum network has faced pushback from the British art community over the past year after it quietly resumed contact with d'Offay following a brief period in which Tate said it would not work with d'Offay.
"Tate and Anthony d'Offay have agreed to end their relationship," Tate and d'Offay said in a statement released on Friday. Tate also said it would return works that were on loan from d'Offay and a company registered in his name.
A 2018 Observer report first revealed the allegations of sexual harassment. The accusations came from several women—all of whom were not named in the report—who had worked with d'Offay; two had been employed by his London gallery, which closed in 2001. The women described alleged instances of … Read the rest
Uncoiled Rope Sprawls Across Canvases and Open Spaces in Organic Forms by Artist Janaina Mello Landini
"Ciclotrama (expansão)" (2019), 4 Ciclotramas of "expansion" series with varied sizes, black and blue ropes, 270 x 600 x 400 centimeters. Zipper Galeria, São Paulo, Brazil. Photo by Gui Gomes. All images © Janaina Mello Landini, shared with permission
Janaina Mello Landini (previously) unbraids lengths of rope to create fibrous labyrinths that breach canvases' edges and crawl from floor to ceiling. Including both sprawling site-specific installations and smaller pieces confined to a few dozen centimeters, the São Paulo-based artist's body of work is broad. All of her projects, though, explore tension and space as they spread into arboreal forms or perfectly round networks.
Her recent works include a massive tree-like installation that fans out across Zipper Gallery's floor and walls into delicate, tape blossoms. Another is a smaller, numbered piece that was born from the artist's response to the ongoing COVID-19 pandemic. "My days are quite slow … Read the rest
SculptureCenter Director Christian Rattemeyer Departs After Less Than a Year
After just 10 months as director, Christian Rattemeyer has departed New York's SculptureCenter. Artforum first reported news of his departure on Friday morning.
According to Artforum, SculptureCenter, which is located in the Long Island City neighborhood of Queens, did not provide a reason for Rattemeyer's departure. "I want to thank the incredibly talented staff and leadership at SculptureCenter," Rattemeyer said in a statement. "I have enjoyed being part of an independent and artist-driven institution leading the conversation on contemporary art."
Artist Carol Bove, the chair of SculptureCenter's board, said in a statement, "On behalf of the entire board and staff of SculptureCenter, we thank Christian for his leadership, curatorial excellence, and global perspective. We wish him all the best in his future endeavors."
On SculptureCenter's website, Kyle Dancewicz, the institution's director of exhibitions and programs, is listed as interim director.
Rattemeyer was named director of SculptureCenter in June … Read the rest
Limp Balloons Slump Over Each Other in Pastel Sculptures by Artist Joe Davidson
"Untitled" (2020), cast tinted hydrocal, 9 x 9 x 4 inches. All images © Joe Davidson, shared with permission
In varying states of deflation, Joe Davidson's pastel balloons sag, slump, and flop in every direction. The limp, elongated forms are stacked on top of one another in seemingly precarious piles and resemble latex tubes filled with days-old air. While the sculptures are playful in both color and form, the Los Angeles-based artist notes that they also hold earnest themes of masculinity and aging, two concepts he's thinking about often.
Davidson prefers to explore new materials and those beyond the bronze, stone, and wood typically used in this medium. "I was in a period about ten years ago where I was working exclusively in Scotch tape," he shares. His more recent interest has been in plaster, which he uses to make the balloons. "There's something about the malleability, chalkiness, and … Read the rest
Jean Dubuffet's Limitless Imagination: Why One of the Artist's Ambitious Environments Is Being Newly Fabricated
Jean Dubuffet, one of the most famous European artists of the postwar era, had an imagination that knew no bounds. In his rough-hewn paintings, drawings, and sculptures ranging from abstraction to childlike figuration, he envisioned altered states in which humanity existed in a form that he believed was closer to its origins. A ceaseless experimenter in the way of materials and forms, he advocated for self-taught or "outsider" practitioners in the field.
These days, Dubuffet may be best known for his large-scale sculptures, which resemble masses of white organic forms sharply outlined in black. He had intended for Le cirque (1970) to be among his monumental ones, but it was never fully realized in a large-scale format—until now. Starting on September 18, Pace Gallery will show a newly fabricated version of Le cirque in its New York gallery. "He both imagined that these things eventually would become physically real … Read the rest
Art Basel Cancels Bellwether Miami Beach Fair Following Pandemic Concerns
The organizers of Art Basel Miami Beach announced today that they had been forced to cancel the scheduled 2020 edition of the fair, which was set to take place during the first week of December in Florida. The news was announced after trading closed on the Swiss stock exchange, where the fair's financially embattled parent company, MCH, is publicly traded.
"It is with great regret and disappointment that we announce the cancellation of our December show in Miami Beach, as we know how crucial our show is for our galleries, as well as for the greater Miami arts community and economy," Noah Horowitz, Art Basel's Americas director, said in a statement. "We thank everyone who shared their perspectives and insights with us over the past months and weeks and look forward to returning to Miami Beach next year to deliver a successful show."
Among the main reasons cited for the … Read the rest
Walker Art Center Staff Reorganization Results in End of Museum's Closely Followed Digital Magazine
The Walker Art Center in Minneapolis recently announced a reorganization of part of its staff, which has resulted in a shuffling of its workers. Nine positions are being created, and five are being eliminated. The most high-profile position to come out of this restructuring is a new senior-level head of public engagement, learning, and impact, which will be held by Nisa Mackie, who was previously the Walker's director of education and public programs. A head of content and communications position is also expected to be created, though it has not yet been filled.
Part of the museum's elimination of several positions includes the loss of the Walker Reader, a digital magazine that published critical texts by artists, curators, and writers about current politics and their impact on art and institutions. For many in the art world, the Walker Reader, which had generated a loyal and international readership, … Read the rest

redpajama_set_name: RedPajamaCommonCrawl


Q. What is the South African (SA) government doing to enhance affordability of telecommunications services?
A. One of the objectives of our government is to make SA competitive and broaden participation of the poorest citizens in our economy. To increase competitiveness in the economy the cost of communication has to be much lower, so we want reliable communication that is affordable. From experience, the cost of communication is cheaper where there is infrastructure and where governments have taken a specific role to see that infrastructure is built and is affordable. Governments can do this using public funds, or tax exemptions.
For SA the challenge is that we are big geographically; we are not small like Singapore where you can put up fibre overnight and cover the whole country. Yet the state has to make infrastructure available. So we have licenced a Second National Operator (SNO), but even then unless you take a deliberate policy to ensure that the network goes beyond big towns, you will not cover all the country.
Q. How does EASSy fit into this picture, and how will you reconcile with private sector players that accuse governments and the New Partnership for African Development (NEPAD) of sidelining them in the EASSy project?
A. It is difficult to argue with people who have invested their own money but our role as governments is to set the policy framework under which the cable will be built. The telecom companies are not terribly thrilled with governments because the governments are saying this cable is not only for profits but has developmental objectives too. Besides, governments will assist to get funding for EASSy under the NEPAD framework. Even the smallest African telecom company can have equity to put in the network. That will promote competition and affordability of EASSy bandwidth.
Q. What benefits will the SNO bring to SA?
A. More competition often leads to lower prices. But the more important thing is that South Africans will have an alternative to Telkom and the mobile operators. It is in the exercise of choices that companies are then forced to attract people, reduce tariffs, and provide a variety of services.
We have already promulgated regulations to enable number portability. What this means is that a customer keeps their number regardless of the mobile operator they are subscribed to. If one is fed up with Cell C, or Vodacom or MTN, they cross to another provider but keep their number. The cost of communication can only go down if you have choices. And if it is easy to make for subscribers to switch, operators will strive to get more customers and to keep those they have. [The Independent Communications Authority of South Africa (ICASA) in early September decided that Mobile Number Portability (MNP) would take effect on November 10 2006 rather than on September 18 as had earlier been announced. Telecom operators had asked to be given up to October 30 or November 30 to ready themselves for MNP – CIPESA].
Q. Telecom companies also need to share infrastructure to lower their capital inputs.
A. There could be government regulations that there should be sharing, because it is rare that those who build their infrastructure allow others to use it. But in some areas in SA there are trials by companies to share infrastructure under the Digital Video Broadcasting venture though which television channels are received via cellphone. For this to be possible you have to build a network afresh. Companies are saying if government says a parastatal will build the network and then they are able to use it, they will be happy. Also, operators also increasingly realising that you don't have to build five highways to Durban.
Q. What will happen after the monopoly which companies like Telkom SA have in SAT 3 ends next year?
A. Already some of the companies in SAT 3 have indicated that the NEPAD principles that we have adopted for EASSy should apply to SAT 3 at the end of the contract period. But they will have to consult on this. I am sure EASSy [bandwidth] will be a lot cheaper and they will want to benefit from that. The ownership protocol we signed [in Kigali on August 29) puts all those things in context and provides for cables on the continent being inter-linked. Government could also spell out what companies that were party to SAT 3 before we signed the protocol can do, and what those that wish to access it after the signing can do. I don't envisage major problems in that regard. In SA we shall make sure our international infrastructure is harmonised with the new cable (EASSy).


Maggie literally had me saying, "Amen," throughout the podcast which thankfully, doesn't happen often, but I know you guys will be fist pumping with me as she gracefully and powerfully brings the truth on this episode. I hope ya'll enjoy it as much as I did!
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•	Consumers who have any type of romaine lettuce in their home should not eat it and should throw it away, even if some of it was eaten and no one has gotten sick. This advice includes all romaine lettuce, such as whole heads of romaine, hearts of romaine, and bags and boxes of precut lettuce and salad mixes that contain romaine, including baby romaine, spring mix, and Caesar salad.
•	If you do not know if the lettuce is romaine or whether a salad mix contains romaine, do not eat it and throw it away.
•	Wash the inside walls and shelves of the refrigerator, cutting boards and countertops; then sanitize them with a food-safe sanitizer such as a solution of one tablespoon of chlorine bleach to one gallon of water; dry with a clean cloth or paper towel that has not been previously used.
•	Restaurants and retailers should not serve or sell any romaine lettuce, including salads and salad mixes containing romaine.
CDC and FDA are advising consumers and retailers not to consume, serve, or sell romaine lettuce due to a multi-state outbreak of E. coli O157:H7 infections linked to romaine. Consumers who have any type of romaine lettuce in their home should not eat it and should throw it away, even if some of it was eaten and no one has gotten sick. This advice includes all romaine lettuce, such as whole heads of romaine, hearts of romaine, and bags and boxes of precut lettuce and salad mixes that contain romaine, including baby romaine, spring mix, and Caesar salad.
At this time, there is not enough information for FDA to identify the source of the contamination needed for a recall. Instead, FDA has requested that industry voluntarily withdraw the product from the market until the outbreak is over or a specific source is identified. Romaine lettuce is also suspected in current illnesses in Canada.
There is no genetic link between the current outbreak and outbreak linked to romaine from the Yuma growing region earlier this year. However, there is a genetic link between this current outbreak and the outbreak in Fall 2017 linked to leafy greens that affected consumers in both Canada and the U.S.
The symptoms of Shiga toxin-producing (STEC) E. coli infections vary for each person but often include severe stomach cramps and bloody diarrhea. If there is fever, it is usually less than 101 degrees Fahrenheit. Most people get better within 5–7 days, but others can have very severe or life-threatening infections. People need to take action if they have symptoms of an E. coli infection by talking with their healthcare providers and potentially seeking care.


Convert a Battery-powered Sensor to Mains?
Okay, I have Konnected for my wired home system and it works (though I'm finding that it generally about a second or two slower to report status than my wireless devices).
However, I have a few places I'd like to add sensors, but I'm really against adding more devices that need batteries, ESPECIALLY those that are outdoors. I tried that last winter and those sensors just ATE batteries. I then realized that in these places I have easy access to power outlets right next to where sensors can go.
How hard would it be to take a wireless sensor and power it via an outlet with a power converter between the two? Has anyone done this?
Cut the end off of the power adapter below. Plus to Plus, Negative to Negative and wire in parallel for multiple sensors .
Thanks so much. Perfect info.
Lots of people have done this in lots of different ways.
Check the quick browse lists in the community – created wiki, look down near the bottom of that page for the "project reports" section, and then choose the list for "power" projects. That should turn up most of the threads discussing various options for converting from battery powered to mains.


DCC Archive Vinyl over tape and cd?
Discussion in 'Music Corner' started by DanG, Sep 11, 2001.
I've been turning this one over in my head for a week now waiting for this board to be back up. I don't know from Direct to Disk, HDD, DVD-A, or Sony HDCD, or other new formats. My favorite format for music is the original masters on 180g vinyl, virgin vinyl, or regular vinyl; reel-to-reel then casette tape; OMR gold cd, then OMR aluminum cd; then cd. Interestingly the most convenient formats seem to have the worst fidelity.
Comments or difference of opinion?
Well, my question is, if you don't know the difference between the digital formats, have you heard any of them?
I have one HDCD disc, The Pizza Tapes. I haven't given it a good listen on my best equipment yet. Also, it's been my experience Grateful Dead records are usually sonically superior, which may make it more difficult to attribute better fidelity soley to HDCD.
I have not heard the other digital formats. Is it your opinion they are a better experience than vinyl and tape?
<STRONG>I've been turning this one over in my head for a week now waiting for this board to be back up. I don't know from Direct to Disk, HDD, DVD-A, or Sony HDCD, or other new formats. My favorite format for music is the original masters on 180g vinyl, virgin vinyl, or regular vinyl; reel-to-reel then casette tape; OMR gold cd, then OMR aluminum cd; then cd. Interestingly the most convenient formats seem to have the worst fidelity.
I would tend to agree with you that analog usually sounds better than conversions to digital of the same music. Having said that, I have to admit that digital is more convenient. Now that SACD (Sony's new Direct Stream Digital format) is beginning to take hold, the potential exists for capable engineers like Steve Hoffman to, finally, produce digital recordings that may be all but indistinguishable from their original analog counterparts.
I know it's just a personal opinion and we each feel diferently about the audio quality of different formats, but I must say that i have a hard time taking seriously anyone who seriously thinks that cassette tapes sound better than compact discs.
Have you ever listened to an MFSL Original Master Recording dolby B cassette? I know they are hard to find now, but I have six, and they are worth a listen. Beach Boys Surfer Girl, Beatles MMT, Bowie's Let's Dance, Jackson's Night and Day, Dark Side of the Moon, and Ritenour's Captain Fingers. In all honesty I do not have a CD version of any of these albums, but they are so satisfying I have no desire to purchase the CD's.
I haven't heard one of the OMR cassettes from MoFi.
To me playing vinyl is a ritual, I listen to the music, read the lyrics, liner notes, admire the artwork. Vinyl makes me happy, simple as that.


text:
Home > Business
From Outsourced To Open: The continuing evolution of the drug discovery business model
Dr Mary Canady
One doesn't have to look far to find that the large pharmaceutical business model has many market forces working against it, such as patent expirations, dwindling pipelines, and reduced R&D productivity. However, these factors are driving smaller organisations and individuals to take on small molecule and biological drug development, sometimes with great success.
Virtual drug discovery entrepreneurs, armed with their experience, personal networks, online tools, and countless contract research organisations (CROs) who will manufacture and test their drug candidates, have shown that drugs can be developed outside the confines of traditional biotech and pharma.
This movement has in turn sparked a more open approach to the development of medicines, which is being embraced at all levels of the industry. Examples of virtual and open discovery organisations from the San Diego region, where the author resides, are highlighted in this review, as well as those from other regions as needed.
As far as failing business models go, Pharmaceutical companies could arguably be placed in the same category as airlines, as we are no longer surprised to hear of major cutbacks or other signs of distress. The 2011 CMR International Pharmaceutical R&D Factbook (1) indicated that while drug sales are increasing, only 5% are from products launched in the last five years. Of the 21 NMEs launched in 2010, down from 26 in 2009, only one-third were from larger companies.
This downward spiral will continue as R&D expenditures reached a three-year low. The Fitch Global R&D Pipeline reports for 2011 indicated that acquisitions, not internal R&D, are driving the pipelines of big pharma and that 2012 may be the most challenging year for them due to different forces, most notably a cascade of patent expirations (2,3).
Although the success rate for inlicensed compounds is on average 20% lower than those developed in-house (1), they are desperately needed to fill Pharma's dwindling pipeline. As shown in Figure 1, the dearth of marketed drugs leads to fewer financial resources for R&D which will result in an implosion unless their business model is changed.
What factors are leading pharma on this downward spiral? A 2008 Harvard Business Review (HBR) article (4) sheds light on the 'success-seeking' behaviour of large pharma. Negative information is ignored, or the correct experiments aren't done in the first place due to the fear of not succeeding. Smaller or virtual companies succeed by becoming the anti-pharma, by building a culture in which the experiment is more important than the success of the programme.
The HBR article details the success of Chorus, a 22-person company spun out of Lilly whose goal is to evaluate compounds quickly and autonomously. By choosing smaller scale, 'killer' experiments, Chorus has made go/no go recommendations resulting in a 3-10 fold 'productivity enhancement (5). Chorus was also able to make its decisions in a capital-efficient manner by utilising contract research organisations (CROs) in an 'a la carte' fashion rather than continuously staffing resources.
The wide selection of drug discovery CROs is one of the major drivers of small and virtual company success. Kevin Lustig, CEO of Assay Depot, an online CRO marketplace, indicates that it has 6,491 CROs in its directory (Figure 2) (6).
Those who are concerned about job loss in the countries where many drug discovery scientists are trained should note that the majority are in the US and Europe. The Assay Depot directory enables small companies by providing a wealth of information about the drug discovery process, as CROs are smartly categorised as being in Biology, Chemistry, DMPK, Pharmacology or Toxicology, with more detailed subgroups.
The goBalto directory also includes clinical research organisations and related businesses and lists more than 16,000 entities. These portals provide easy access to information, ratings, and even ordering and managing outsourcing. Additionally, outsourcing partners can be found through networks such as LinkedIn, either through personal connections, searches, or groups (there are even several LinkedIn groups dedicated to outsourcing).
Conferences such as the Biotechnology Industry Organisation annual meeting and EBD Group partnering events have developed online applications to facilitate meetings between pharma and biotech collaborators, although the emphasis is normally on later stage partnerships.
Virtual drug discovery programme managers are often veterans of the industry and rely heavily on their own networks and experience to get the work done. Jim Hauske, founder of Sensor Pharmaceuticals, spoke about forming his virtual R&D network at a July 2011 event held by the San Diego Biotechnology Network (SDBN) (7), describing 10 companies he outsources to as his 'collaborators.' Hauske's talk was followed by a panel of experts from both sides of the outsourcing fence, and they reiterated this need to work closely.
Are most teams truly virtual, in other words do geographical differences matter at all? At the SDBN event, the consensus was that only barriers to working with companies in different regions were time zone differences. Normally, meeting in person near the beginning of the project is desired, but not essential. Indeed, CRO services have become so all-inclusive that Sensor's Hauske said that he's developed assets in which he's never actually held a vial of a compound.
The availability of video conferencing applications for individuals and small companies, which adds the human connection to a collaboration, allows meetings to take place across time zones. To manage projects, collaborative software such as SharePoint allows for secure file sharing and project management. More recently, Collaborative Drug Discovery introduced a webbased drug discovery data management product called CCD Vault, which is more affordable than the enterprise systems larger companies use.
It has been suggested that IT advancements are the key to streamlining the drug discovery and development process, and Chorus' planning and management application 'Voice' is touted as being integral to their success.
While these companies can be 100% virtual in theory, there are benefits to looking locally for collaborators, including closer communication and reagent or equipment exchange. In San Diego, our biotechnology network is one of several grass roots organisations facilitating networking in the region, with 6,500 connected via a LinkedIn Group.
The San Diego Entrepreneurs Exchange (SDEE) was founded in 2009 and holds bimonthly meetings attracting 100-200 biotech professionals interested in the success of biotech business in the region. They've also created an online 'incubator' in which laboratory resources can be listed for rent or sale. San Diego's regional hi-tech/biotechnology development group CONNECT has also initiated a 'Nearsourcing' program which helps companies meet their outsourcing needs locally.
Who starts a virtual company, and how?
Jim Hauske outlined five requirements for starting a successful virtual drug discovery company at our event in San Diego:
- A novel idea
- Someone else's money
- Operational and deal making experience
- Experience raising money
- An extremely thick skin
Hauske was too modest to mention that he has the right provenance for the job, which likely made his pathway successful. Finding and evaluating an idea as novel and potentially successful, and the wisdom that leads it from concept to asset requires expertise that few possess.
Hauske was involved in the development of Zithromax at Pfizer, and after further experience managing projects and outsourcing at Sepracor, has become a serial entrepreneur. He has licensed technologies and small molecule clinical candidates through three of his companies, and his current company Sensor Pharmaceuticals focuses on treatments for metabolic and cardiovascular disorders.
Virtual drug discovery is by no means limited to the development of small molecule drug development, as CROs who develop and produce antibodies and biologics continue to become more plentiful and experienced. Assay Depot lists more than 670 antibody services providers in its directory, and more than 400 services (not all that are listed as vendors also list their services).
San Diego's BioAtla leverages an antibody and other protein production sites in Beijing to cut costs, and works on either a collaborative or project by project basis. In addition, BioAtla is in tune with current intellectual property (IP) procedures and regulations, and helps its clients successfully navigate them, without laying claim to them. BioAtla has worked closely with Femta Pharmaceuticals, a San Diego-based virtual company, resulting in an IND filing in August 2011.
This is a limited example but in essence, any pre-clinical or clinical activity, is available on an out-sourced basis. Entrepreneurs that can develop the proper network are able to accomplish exactly what a classical biotech or pharma company can in terms of drug development. Recently, the returns on a few virtual companies cannot be denied. One recent example from the antibody space was the sale of Stromedix to Biogen Idec for a Humanized monoclonal antibody to integrin v6 being developed for idiopathic pulmonary fibrosis.
The deal was extremely valuable with $75 million as an upfront payment and subsequently backed with a total of $487.5 million in potential milestones. The development of the Stromedix product was totally on a virtual basis and the exit was on par with peers structured as a classical company.
That said, one of the biggest challenges faced by virtual companies is finding funding in the first place. As Hauske pointed out, he used his own money initially, but indicates this strategy is not optimal. Many small biotechnology companies are relying on creative sources of funding such as small business innovation research (SBIR) grants. Scott Struthers, Founder & CSO at Crinetics Pharmaceuticals and member of the SDEE organising committee, said "The NIH SBIR programme has long been a crucial driver for company creation in the biotech space.
In the last few years, its role has become increasingly important as early stage funding from traditional venture capital (VC) sources continues to dry up." This funding allows small companies to initiate projects leading to growth, albeit slow compared to that achievable with VC funding.
We've all seen VC funding being used frivolously however, and perhaps this slow growth is necessary for effective drug discovery. Patient advocate groups, such as the Michael J. Fox Foundation for Parkinson's Research, seem to have found a good blend of providing targeted funding while fostering collaboration between teams.
Creative financing can cross over to CROs as well to enable virtual drug discovery. For example, Seattle-based Emerald BioStructures is a key partner with the Seattle Structural Genomics Center for Infectious Disease (SSGCID). Working within the consortium, Emerald has solved the 3D structures of more than 450 novel infectious disease target proteins since the start of the programme in 2007 to enable the pharma and biotech industry in the development of new antibiotics.
The need to crystallise this many targets at once has led Emerald to develop a multi-target parallel process approach, which they believe will meet the needs of drug discovery companies which are looking for a capital-efficient process. The evolution of CROs which have developed expertise on a specialised aspect of the process and have also minimised the cost can enable a virtual drug discovery project greatly.
CROs must win every project they are granted, resulting in competition that is good for streamlining the process. Perhaps in 10 years we will wonder how large pharmaceutical companies existed, having to fund dozens of biologically and chemically disparate programmes simultaneously, juggling highly specialised resources between each as their pipelines evolved. Smaller organisations are being developed to better mitigate the risk of drug discovery.
San Diego's Amira Pharmaceuticals was acquired by Bristol- Myers Squibb in July of 2011 for $325 million with the option for $150 million in milestone payments. This company, which had shrunk to 25 employees by this time, was a drug hunting 'team' which had amassed a bevy of small molecule assets. An Xconomy article about Amira's success (8) pointed out that this collection of compounds likely resulted from the big pharma backgrounds of the founders, who continually hedge their bets.
Based on their success, Amira cofounder Peppi Prasit started a new venture called Inception Sciences, which will spin out separate companies for each development programme. VC firms can then pick which programme/company to fund in an 'a la carte' manner. This model seems to represent a way for VCs to bet on one horse, rather than all of them at once, to win the race, but it may be unique in that Amira already has a proven 'blood line.'
The success of small or virtual drug discovery teams has engendered a collaborative spirit with big pharma, leading to benefits for all. In 2009, Eli Lilly launched the 'Open Innovation Drug Discovery' (OIDD) programme, with a supporting online platform in 2011 which allows researchers to submit compounds to be tested using their assays. Lilly does not have access to the structures of the compounds during the screening, but has the 'first rights to negotiated access' to compounds of interest.
As of September 2011, Lilly had a total of 252 affiliations globally and had screened 42,000 compounds (9). As of November 2011, OIDD has resulted in three signed agreements with academic institutions, and by all accounts Lilly continues to be enthusiastic about the project.
The fact that Lilly's three negotiated deals are with academic institutions, rather than biotech companies, also represents the momentum of the translational research movement, which has been partly fuelled by pharma R&D scientists who returned to academia and the growth of strong university core resources. Peter Schultz, long time San Diego entrepreneur and faculty member of The Scripps Research Institute, has announced the formation of the California Institute for Biomedical Research (Calibr) with $90 million funding from Merck.
Calibr will perform early stage research at 'arm's length' from Merck, and Schultz commented to Xconomy (10) that collaboration will be much easier with this non-profit. As with Chorus and Inception Sciences, it appears Pharma needs to get 'out of its own skin' to perform drug discovery more effectively.
Pfizer and Johnson & Johnson also support drug discovery incubators in San Diego, and while it appears the former appears to be ramping down, J&J's Janssen Labs is taking off, launching in January 2012 with some fanfare. The 30,000sq ft space is described as a 'no strings attached' facility where start-ups can use facilities in a modular manner, expanding to using more when needed.
The space is meant to foster 18-20 companies, and J&J will take no equity in them and states that they truly are creating the incubator to 'fertilise the soil' for the drug discovery industry as a whole (11). Besides the great PR that the company will receive from this endeavour, it is likely that they will benefit down the road from an influx of new ideas and perhaps a talent pool.
An 'extreme' version of open drug discovery
The virtual drug discovery paradigm has shown a path towards the development of new medicines through increased collaboration between increasingly experienced individuals and organisations. An open model is the next progression and promises to shed even more light on the path to a successful drug.
The virtual model is not without critics who say that drug development should not be relegated to VCs who may be taking random 'shots on the goal' in financing 'throwaway' biotechs (12). Similarly, the open model may face criticisms as it evolves, as complications with intellectual property and later stage funding will likely emerge. Soon the success rate of these assets in the clinic will be assessed, at which point we'll be able to fully judge the progress. DDW
Thanks to Jim Hauske and Michael Bayewitch for useful discussions and comments regarding this article.
Dr Mary Canady is the founder of Comprendia, a firm specialising in helping biotechnology and life science companies grow through the creation, commercialisation and communication of value. She has a PhD in Biochemistry and 10 years of direct experimental experience at Duke University, University of California Riverside and The Scripps Research Institute. In 2000, Mary left academia and has worked in marketing and business development roles at Invitrogen, EMD Biosciences and ActiveSight (Rigaku). In 2008, she founded the San Diego Biotechnology Network, a grass roots organisation using online and face-to-face interactions to promote growth in the region. Mary keeps current with drug discovery trends through her involvement with companies in the San Diego region and with clients who are engaged in pharmaceutical research.
1 Thomson Reuters (2011, June). 2011 CMR International Pharmaceutical R&D Fact Book. Retrieved from http://www.techstreet.com/direct/CMRFactbook_Exec_Sum.pdf.
2 Fitch Ratings Ltd (2011, September 16). Global Pharmaceutical R&D Pipeline – Second-Quarter 2011. Retrieved from http://fitchratings.com.
3 Fitch Ratings Ltd (2011, December 20). Global Pharmaceutical R&D Pipeline – Third-Quarter 2011. Retrieved from Fitch Ratings.
4 Bonabeau, Eric N. B. (2008, March). A More Rational Approach to New-Product Development. Harvard Business Review , pp. 96-102.
5 Chorus Pharma (n.d.). About Us. Retrieved March 16, 2012, from Chorus Pharma: http://www.choruspharma.com/about-us.html.
6 Chen, T (2012, 3 14). [Infographic] Drug Discovery Goes Global: Location of CROs Around the World. Retrieved from Assay Depot Blog: http://blog.assaydepot.com/infographic-drugdiscovery-goes-global-locati.
7 Hull, LM (2011, July 28). Virtual Biotech Part 1: What We Learned About Effectively Outsourcing a Drug Discovery Program. Retrieved from San Diego Biotechnology Network: https://sdbn.org/.
8 Bigelow, BV (2011, 12 23). A Sweet Deal: How Amira Reinvented Itself as a Drug Discovery Engine. Retrieved from Xconomy: http://www.xconomy.com/sandiego/2011/12/23/a-sweetdeal-how-amira-reinvented-itself-as-a-drug-discovery-engine/.
9 Lowe, D (2011, 9 14). Lilly's Open Screening Program: An Update. Retrieved from In The Pipeline: http://pipeline.corante.com/archives/2011/09/14/lillys_open_screening_program_an_update.php.
10 Timmerman, L (2012, March 16). Peter Schultz on New Merck-Funded Institute: 'We're Getting Lots of Resumes'. Retrieved from Xconomy: https://www.xconomy.com/.
11 Timmerman, L (2012, January 18). J&J Opens San Diego Biotech Startup Center, Says 'No Strings Attached'. Retrieved from Xconomy: https://www.xconomy.com/
12 Lyman, S (2012, February 16). Will New Business Models Enhance or Endanger Drug Discovery? Retrieved from Xconomy: https://www.xconomy.com/
> How Mergers and Acquisitions Will Drive Oncology Research in 2019
> Integrated Platform Drug Discovery and Development Companies - Part 2: comparative analysis
> Fostering Multidisciplinary Collaboration in Drug Discovery
> Good Laboratory Practice - To GLP or not to GLP?
> Integrated Platform Drug Discovery and Development Companies - Part 1
> Astrazeneca R&D - Improving Drug Development Productivity With Better Predictivity
> Disruptive Approaches To Accelerate Drug Discovery and Development (Part 2)
> Emerging Drug Discovery Alliance Models
> The Discoverome - Creative Destruction of Barriers for Faster to Patient Medicines R&D


text:
La memoria de mi padre es una película chilena dirigida y escrita por Rodrigo Bacigalupe Lazzo, estrenada mundialmente el 24 de marzo de 2017 en el Festival de Cine de Málaga. En Chile, fue estrenada el 23 de agosto de 2017 en Santiago Festival Internacional de Cine (Sanfic).

Argumento
Al morir su madre, Alfonso (Jaime Mcmanus) se ve obligado a hacerse cargo de un padre Jesús (Tomás Vidiella), que no soporta, con el agravante que el viejo está perdiendo la memoria, convirtiéndose en un niño alejado de aquel hombre fuerte que alguna vez fue, y obsesionado con que su mujer sigue viva, perdida en un hospital de la costa. Alfonso se adentrará en la aventura de encontrar a una madre que ya no está entre los vivos, pero que sigue presente en el corazón de su padre.

Reparto
 Jaime McManus es Alfonso, el hijo
 Tomás Vidiella es Jesús, el padre
 María Izquierdo es Ester, la mamá
 Luz Jiménez es Julieta, la tía
 Marcial Tagle es Ricardo
 Romina Mena es Antonia
 Tamara Tello es Claudia
 Mireya Sotoconil es Rosa
 Rodrigo Correa es el doctor Correa
 Agustín Ibáñez es Diego

Recepción
La película debutó el 24 de marzo de 2017 en el Festival de Cine de Málaga, donde generó un especial interés en la prensa y críticos presentes. Obtuvo el Primer Premio en la décima versión del Festival Internacional de Cine de Mar del Plata, como Mejor película pargometraje, en Punta del Este, Uruguay.

Premios

Referencias

Enlaces externos

Películas de Chile
Películas dramáticas

redpajama_set_name: RedPajamaWikipedia


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text:
The Story of Rubik's Cube, the World's Most Popular Toy
A perennial puzzle turns 40
By Robert Klara
The event, in case you missed it, was called the Zonhoven Open. It took place in Belgium last March, and it witnessed 18-year-old Mats Valk do something remarkable. The lanky teen picked up a color-scrambled Rubik's Cube, whirred it around in his fingers and slammed it down—solved—in 5.55 seconds. It was a world's record—and still is.
Photo: Nick Ferrari
The doe-eyed Valk is too young and on the wrong continent to remember it, but the feat he performed in a few moments was one that, two generations ago, perplexed much of America for months.
Robert Klara
@UpperEastRob
robert.klara@adweek.com
Robert Klara is the senior editor of brands at Adweek, specializing in the evolution and impact of brands.


Hello all. I am working on using pscEx's NativeEx_Barebone project to create a very minimal PE environment able to load a massive amount of network drivers and Norton's Ghost 11.5, Ghost Server, and Ghost Explorer (possibly a few others, but those for sure).
I currently have a build capable of loading a few network drivers and all three of the above Ghost executables. I am working on adding as many network drivers as I can find. Currently downloading driverpacks.net LAN packages to give a try.
I am still trying to figure out how to upload the current project up to the forums here, but I think I am going to upload it to a file sharing site and post the link up here.
Thanks RoyM. That looks like it will work. I will try it out tonight after work and let you know asap.
A little deviation here, but does anyone know how to change your profile picture?
You can also easily add a pre-built file to a script and unpack it into the PE or use any of the other commands that deal with attachments.
One question is how are you dealing with the "licensing" of the commercial tools???
@sbaeder: As for the "licensing" for Norton Ghost. I am not including any of Nortons executables. The builder (you) will have to provide their own Ghost files. I have just made a WinBuilder script to copy them into the PE build and (hopefully if I can figure it out) launch them from a menu or automatically. I don't think anything else besides the Windows disk (which the builder will also have to provide) is "licensed".
As for the download. I have a simple website setup ( festerjester.net63.net/ ) that I will use until this project gets closer to finished.
And thanks for the welcome, though I have been around these forums for a few years. I just never had the time to really get into these projects while in college.
Now I do, so now I will.
edit: Oh yeah. I do not have an empty picture frame in my profile settings. I only on my profile page and my posts. None of them do anything.
Edited by FesterJester, 02 August 2014 - 03:48 PM.
Will do and thanks for keeping an eye on the llicensing thing.
Once you reach 100 posts, all member restrictions are removed and you should be able of changing the avatar. This was necessary to keep spammers away from exploiting these features, sorry..
Wow, 100 post. That could take me a while, but thats ok. It's not important that I change my avatar and I completely understand why you did it. I dislike spammers so thanks. I kinda like that my signature is still there even though I can't change it. Not sure if you noticed that Nuno Brito.
I think I am starting to get the hang for this scripting language. Well at least the basics and maybe a little beyond that. It kinda reminds me of the VBScripting language.
Oh heck.. You've been so long with us (and I like your sig) that you also deserve better treatment than having to make 100 posts.
I'd rather seeing you make 10 good posts than those 73 still missing for the promotion. I went to the admin panel and moved you the advanced member category. No more restrictions or nuisances. Hope you enjoy this, thank you for joining our community.
Wow again. You didn't have to do that for me. I shall thank you much for it.
I don't mean to be pushy or anything, but has anyone had the chance to take a look my script over? I am just really interested in seeing what kind of a scripting job I have done.
Sounds like a sound basis for a project.
Because I have no Ghost, I cannot test.
The code over all looks well.
TXTReplace syntax: TXTReplace,TextFile,OldString,NewString replaces in the whole file, nothing about place.
Thanks pscEx. Fixed the TXTReplace syntax and updated on the site.
As for the unnecessary quotes, is it bad to do that or just a more proper coding practice? I just wasn't sure if the quotes were needed so I put them in to be safe.
It makes me happy that I have made my first script as good as I did. It is not as bad of a scripting language as I though, once I got into it.
I thought it was going to be really challenging to learn when I first looked at it. I have yet to get into some of the more advanced stuff though.
Couple things to ask here. First being, what is the best way to put driverpack.net's LAN package into my PE. I currently unzip the LAN Pack into the PENetworks driver folder and let the PENetwork script load them into the build. Does this work or is there a more recommended way to load network drivers. I want to get as many network drivers as I can possibly get into my PE build cause it is going to be used to Ghost many different model computers.
Second being, I have also been searching the forums here and have had no success in finding out if anyone has already made a script for A43, Cubic Explorer, or GO Shell. Can anyone tell me if there are scripts for these file explorers or shells. Also, what is the best shell to run in an XP PE environment?
After almost a year, I have to open this thread up. I have used the current build quite a few times with success almost every time thanks to all who helped here.
Now I would like to know if I can pxe boot this over a network. It would be absolutely awesome if I didn't have to use a disk every time and have a faster loadup time.


Azure Naturals - a brand that creates high-quality facial skincare - has created a professional strength Ultimate Retinol Anti-Wrinkle Serum which is made of 97% natural and 72% organic ingredients. It contains a high strength of retinol while being gentle enough to use on sensitive skin and even around your eyes.
The main ingredient in this serum is retinol, which penetrates the skin to activate collagen and elastin, and promote cellular turnover. The serum also contains Hyaluronic Acid and Vitamin A to improve skin texture and tone while increasing hydration.
I had never used retinol products before, so I followed the instructions for new users and started by applying it every other night with just a small amount of serum and increasing the amount over time. Before applying the retinol serum, I use Azure Naturals Vitamin C serum (review here); Then afterward, I use a moisturizer.
The thick gel-like serum feels really nice on my skin and leaves my face looking more even and radiant. I love using it and do feel like it's making my skin look more youthful. I have sensitive skin and haven't experienced any irritation, redness, or negative effects. It is also helping to keep my skin clear of blemishes and acne.
Ultimate Retinol Anti-Wrinkle Serum is made in the USA with Natural and Organic plant-based ingredients. It contains no alcohol, parabens, or GMO's. It's also cruelty free and never tested on animals.
The best benefit for me is hydration!
My favorite benefit is it evens skin tone and leaves it looking radiant!
best benefit is to keep adult acne away!


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text:
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Operations — January 11, 2023


text:
Q: Complex integration and differentiation for $\gamma:[a,b]\rightarrow \mathbb{C}$ Let $\gamma(t):[a,b]\rightarrow \mathbb{C}$ , $[a,b]\subset \mathbb{R}$,  $\gamma(t)= \gamma_1(t) + i\gamma_2(t)$
$\int_{a}^{b} \gamma(t) dt = \int_{a}^{b} \gamma_1(t) dt + i\int_{a}^{b} \gamma_2(t) dt$ and $\frac{d}{dt} \gamma(t)= \frac{d}{dt} \gamma_1(t)+ i\frac{d}{dt} \gamma_2(t)$
When differentiating and integrating $\gamma_1(t)$ or $\gamma_2(t)$ with respect to $t$, should i treat $\gamma_1$ / $\gamma_2$ as a real-valued function and any complex constant in the formula as a real constant? Then the integration and differentiation rules learned in Calculus will apply nicely.
Please help me by giving explanation on why or why not. Thanks!
For example, $\int_{0}^{\pi}e^{i2t}dt = \bigg[\dfrac{e^{i2t}}{2i}\bigg]^{0}_{\pi}$ . Here, i treat $2i$ as a constant and do the normal integration rule as i have learnt in Calculus.
$\frac{d}{dt}\big[ \sin(3it)\big] =3i\cdot \cos(3it)$. Here, i treat $3i$ as constant and do the normal chain rule as i have learnt in Calculus.

A: The simple answer is that the 'usual facts' about derivatives for real functions do not automatically transfer to complex functions. For example, $\ln(|z|)$ does not have a complex derivative with respect to $z$. So your question is a good one; since you are not assuming that properties for reals carry over to complex numbers. (See this post for another common kind of error due to such assumptions.)
$
\def\lfrac#1#2{{\large\frac{#1}{#2}}}
$
So what holds? If you build a more general framework for differentiation, such as sketched in this post, you can establish many basic properties of derivatives, of which I shall list some below. This framework is not only more intuitive, it also clearly shows why complex differentiability is much stronger than real differentiability.
Specifically, given any real variables $x,y$ varying with real parameter $t$, for $\lfrac{dx}{dy}$ to be defined when $t = p$ we merely need $\lfrac{Δx}{Δy}$ to have a limit as $t \to p$. This is along a path. In contrast, given complex variables $x,y$ varying with complex parameter $t$, for $\lfrac{dx}{dy}$ to be defined when $t = p$ we need $\lfrac{Δx}{Δy}$ to have a limit as $t \to p$ along all possible paths.
But since the definition itself does not care what type the parameter is, nor what type the variables are, except that the values come from a field with a norm, all the basic properties that arise from algebraic identities hold with the same proof. Time for the examples.

Given any complex variables $x,y,z$ varying with some parameter $t$:

*

*$\lfrac{dc}{dx} = 0$ whenever $\lfrac{dc}{dx}$ is defined, for any constant $c$.

*$\lfrac{d(c·y)}{dx} = c·\lfrac{dy}{dx}$ whenever $\lfrac{dy}{dx}$ is defined, for any constant $c$.

*$\lfrac{d(y+z)}{dx} = \lfrac{dy}{dx}+\lfrac{dz}{dx}$ whenever $\lfrac{dy}{dx},\lfrac{dz}{dx}$ are both defined.

*$\lfrac{dx}{dz} = \lfrac{dx}{dy}·\lfrac{dy}{dz}$ whenever $\lfrac{dx}{dy},\lfrac{dy}{dz}$ are both defined.

*$\lfrac{d(y·z)}{dx} = \lfrac{dy}{dx}·z+y·\lfrac{dz}{dx}$ whenever $\lfrac{dy}{dx},\lfrac{dz}{dx}$ are both defined.

*$\lfrac{d(x^n)}{dx} = n·x^{n-1}$ whenever $\lfrac{dx}{dt}$ is defined, for any natural $n \ge 1$.

*$\lfrac{d(\exp(x))}{dx} = \exp(x)$ whenever $\lfrac{dx}{dt}$ is defined.

*$\lfrac{d(\cos(x))}{dx} = -\sin(x)$ whenever $\lfrac{dx}{dt}$ is defined.

*$\lfrac{d(\sin(x))}{dx} = \cos(x)$ whenever $\lfrac{dx}{dt}$ is defined.

*$\lfrac{d(\ln(x))}{dx} = \lfrac1x$ whenever $x \notin \mathbb{R}_{\le 0}$ and $\lfrac{dx}{dt}$ is defined. (Here taking principal branch for $\ln$.)

In particular, we can see how these apply to your examples:

*

*$\lfrac{d(\sin(3it))}{dt} = \lfrac{d(\sin(3it))}{d(3it)}·\lfrac{d(3it)}{dt} = \cos(3it)·3i$. Here $t$ is a real parameter.

*$\lfrac{d(\sin(3iz))}{dz} = \cos(3iz)·3i$ where $z$ is a complex parameter too, corresponding to the fact that $( z \mapsto \sin(3iz) )$ has a complex derivative.

*$\int \exp(i2t) dt = \lfrac1{2i}·\exp(i2t) + c$ for some constant $c$, because $\lfrac{d(\lfrac1{2i}·\exp(i2t))}{dt} = \exp(i2t)$ everywhere.

*If $z = x+y·i$ where $x,y$ are real variables varying with real parameter $t$, then by the above properties $\lfrac{dz}{dt} = \lfrac{dx}{dt}+\lfrac{dy}{dt}·i$. Even if the expression for $x$ uses complex numbers, you can use the above properties to compute $\lfrac{dx}{dt}$. For example if $x = \exp(it)+\exp(-it)$, which is always real, then $\lfrac{dx}{dt} = i\exp(it)-i\exp(-it)$.

redpajama_set_name: RedPajamaStackExchange


text:
Q: jQuery confirm / cancel home made function not working I've made my own, home-made, yes/no function but it won't work.
Here is the function:
function CoverAndShow (title, text, type) {
    if (type == "confirm") {
        $("body").append("

" + title + "

" + text + "
<input class='ok' type='button' value='OK' /><input type='button' class='cancel' value='Cancel' />
");
    }

    $(".ok").click(function() {
        return true;
    });

    $(".cancel").click(function() {
        return false;
    });
}

And here is my code for click "OK" in the function:
    $("#ask").click(function() {

    if (CoverAndShow("Title","Should I operate?", "confirm") == true) {
        alert("true");
    }

This won't work and won't return anything.
Help would be highly appreciated!

A: You're going to need to use a callback here. You can't return from this kind of function (look up asyncronity). You pass a function as the last parameter to CoverAndShow, and then it gets called with the return value.

function CoverAndShow (title, text, type, callback) {
    if (type == "confirm") {
        $("body").append("

" + title + "

" + text + "
<input class='ok' type='button' value='OK' /><input type='button' class='cancel' value='Cancel' />
");
    }

    $(".ok").click(function() {
        callback(true);
    });

    $(".cancel").click(function() {
        callback(false);
    });
}

$("#ask").click(function() {

   CoverAndShow("Title","Should I operate?", "confirm", function(ret){
      if (ret) { // no need to explicitly check for true
         alert("true");
       }
    });
});

ask


I think it's telling you it can't add another dialog to db. I am almost certain that's what's happening.
Do you see any other errors from the DB level in the OpenSIPS logs ? What DB backend are you using ?
It seems that for some reason, the dialog DB inserts are failing, but more ERROR messages should appear in such a case from the db_mysql module..
I keep getting these errors.
Would it be better to change the version of opensips?
What can mean "Column 'callee_contact' cannot be null" ??
Its db schema problem. The field dialog.callee_contact is set as "NOT NULL", while you are getting NULL contact from upstream (most likely in BYE from callee side, as some old PSTN gateways running at many termination providers do not add "Contact" header in BYE request). Please check SIP trace and confirm or attach that here for our review.
For a workaround you can modify dialog table and allow callee_contract field to be NULL. However i am not sure if this won't break anything else.
can someone said me if really modify dialog table and allow callee_contract field to be NULL on DB could break anything??
Most probably not. OpenSIPS usually does updates/inserts on this table. Only if OpenSIPS is configured to restore it's dialogs from DB in case of restart then you might want to make a test just to be sure it won't complain.


This Savage Song and Our Dark Duet ask the reader to rethink how you define the word monster. Is it a definition that applies to everyone or does it change based on the person and the circumstances they find themselves in? Our Dark Duet was a great end to a duology that makes you wonder about the grey areas in morality.
Our Dark Duet picks up 6 months after the conclusion of This Savage Song. Kate is in Prosperity hunting monsters and trying to start a new life. August is in Verity trying to salvage what is left of his life and city. Sloan has taken over for Callum and is letting the monsters rule and terrorize the North Side of the side.
Kate is drawn back to her past in Verity when she encounters a new threat, a shadow monster that is wreaking havoc. After an encounter with the new threat Kate knows she has to return to Verity and confront her past actions and choices.
August is trying to redefine himself. He is trying to become what the city needs, someone who can fight and can put his emotions aside. He believes that trying to become human is useless and futile now. He can only protect the people if he accepts who he is and uses his power to help instead of hurt.
When Kate returns home she finds a new August, a city falling apart, mistakes from her past in corporeal form and a threat she can't name or see. She realizes that to save the innocent people and fix the mistakes her father made she has to accept her own mistakes. She also has to help August figure out that he has to find a balance between the two sides of himself to save the city.
What attracted me to this series initially was the idea of violence creating literal monsters. In this last book the definition of monster was explored, showing that a label does not always give you a full picture of the person you are dealing with. Labels are one way of classifying the people and world around us but it is a heavily flawed system.
This book took off from page one and didn't slow down until the last page. We were on this constant chase to not only find the new monster but also to put a stop to it. Through the chase we learned who our characters were as full people and just what they were capable of.
Kate and August's stories wrapped up in just the right way. Kate, who spent her life trying to prove her worth and strength, found an inner strength inside of herself. She realized she is flawed but that does not make her a bad person. She learned that you get to decide who you are. You will make mistakes, that is inevitable, but in the end it is about what you learn from those mistakes that matter. You can't run from them and you can't hide from them.
When danger and chaos is staring you in the face you fight and you fight without losing yourself. You can be strong without hurting the people around you. You define strength. You define who you are.
August spent much of the first book trying to fight who he was. He wanted to be human, didn't want his power or to use that power. In the end he learned you can't rum from who you are. Like Kate he learned it is about what you do more than what you are.
August learned he can find a balance between the park and light. He is a "monster," which comes with power and responsibility but he is also human. He eats, sleeps, breathes and feels. He loves and that love, he learns, is not a weakness.
I loved that this book challenged the idea of labels and highlighted the detrimental power they can have. August was labeled a monster which made people fear him. They didn't know him but that one word made them think that they did. Same thing happened with Kate. She was a "Harker,"which caused people to assume they knew what she valued and wanted.
Labels do nothing but gives us a simpler way to define things and people. Unfortunately we think that labels tell us all that we have to know. We think by hearing a few words were know a person or a group of people. In reality we know nothing but a preconceived notion. Labels won't give you the inner person they will give you what people assume about a group or a person. In the end we have to learn that we need to approach people with an open mind and allow them to define themselves to us. Once we do we can learn that people are diverse and difficult to place into small little boxes.
The ending of this book was perfect. It was tragic but it was how this series should have ended. There were two paths one that was easy and predictable and another that hurt but was poetic and created hope. Victoria Schwab took the second path. We saw that the world is not doomed. Despite the dark that surrounds the city there is light and that light can be seen through the people you may have believed were capable of nothing but darkness. I like that the book ended on hope and showed that anyone can save everyone. You just have not allow yourself to be scared and to let your heart decide the way.


text:
#if defined(_MSC_VER)
#pragma once
#endif

#ifndef PBRT_CORE_PARAMSET_H
#define PBRT_CORE_PARAMSET_H

// core/paramset.h*
#include "pbrt.h"
#include "fileutil.h"
#include "geometry.h"
#include "texture.h"
#include "spectrum.h"
 #if (_MSC_VER >= 1400)
 #include <stdio.h>
 #define snprintf _snprintf
 #endif
#include <map>
using std::map;

// ParamSet Declarations
class ParamSet {
public:
    // ParamSet Public Methods
    ParamSet() { }
    void AddFloat(const string &, const float *, int nItems = 1);
    void AddInt(const string &, const int *, int nItems);
    void AddBool(const string &, const bool *, int nItems);
    void AddPoint(const string &, const Point *, int nItems);
    void AddVector(const string &, const Vector *, int nItems);
    void AddNormal(const string &, const Normal *, int nItems);
    void AddString(const string &, const string *, int nItems);
    void AddTexture(const string &, const string &);
    void AddRGBSpectrum(const string &, const float *, int nItems);
    void AddXYZSpectrum(const string &, const float *, int nItems);
    void AddBlackbodySpectrum(const string &, const float *, int nItems);
    void AddSampledSpectrumFiles(const string &, const char **, int nItems);
    void AddSampledSpectrum(const string &, const float *, int nItems);
    bool EraseInt(const string &);
    bool EraseBool(const string &);
    bool EraseFloat(const string &);
    bool ErasePoint(const string &);
    bool EraseVector(const string &);
    bool EraseNormal(const string &);
    bool EraseSpectrum(const string &);
    bool EraseString(const string &);
    bool EraseTexture(const string &);
    float FindOneFloat(const string &, float d) const;
    int FindOneInt(const string &, int d) const;
    bool FindOneBool(const string &, bool d) const;
    Point FindOnePoint(const string &, const Point &d) const;
    Vector FindOneVector(const string &, const Vector &d) const;
    Normal FindOneNormal(const string &, const Normal &d) const;
    Spectrum FindOneSpectrum(const string &,
                             const Spectrum &d) const;
    string FindOneString(const string &, const string &d) const;
    string FindOneFilename(const string &, const string &d) const;
    string FindTexture(const string &) const;
    const float *FindFloat(const string &, int *nItems) const;
    const int *FindInt(const string &, int *nItems) const;
    const bool *FindBool(const string &, int *nItems) const;
    const Point *FindPoint(const string &, int *nItems) const;
    const Vector *FindVector(const string &, int *nItems) const;
    const Normal *FindNormal(const string &, int *nItems) const;
    const Spectrum *FindSpectrum(const string &, int *nItems) const;
    const string *FindString(const string &, int *nItems) const;
    void ReportUnused() const;
    void Clear();
    string ToString() const;

private:
    // ParamSet Private Data
    vector<Reference<ParamSetItem<bool> > > bools;
    vector<Reference<ParamSetItem<int> > > ints;
    vector<Reference<ParamSetItem<float> > > floats;
    vector<Reference<ParamSetItem<Point> > > points;
    vector<Reference<ParamSetItem<Vector> > > vectors;
    vector<Reference<ParamSetItem<Normal> > > normals;
    vector<Reference<ParamSetItem<Spectrum> > > spectra;
    vector<Reference<ParamSetItem<string> > > strings;
    vector<Reference<ParamSetItem<string> > > textures;
    static map<string, Spectrum> cachedSpectra;
};

template <typename T> struct ParamSetItem : public ReferenceCounted {
    // ParamSetItem Public Methods
    ParamSetItem(const string &name, const T *val, int nItems = 1);
    ~ParamSetItem() {
        delete[] data;
    }

    // ParamSetItem Data
    string name;
    int nItems;
    T *data;
    mutable bool lookedUp;
};

// ParamSetItem Methods
template <typename T>
ParamSetItem<T>::ParamSetItem(const string &n, const T *v, int ni) {
    name = n;
    nItems = ni;
    data = new T[nItems];
    for (int i = 0; i < nItems; ++i) data[i] = v[i];
    lookedUp = false;
}

// TextureParams Declarations
class TextureParams {
public:
    // TextureParams Public Methods
    TextureParams(const ParamSet &geomp, const ParamSet &matp,
                  map<string, Reference<Texture<float> > > &ft,
                  map<string, Reference<Texture<Spectrum> > > &st)
        : floatTextures(ft), spectrumTextures(st),
          geomParams(geomp), materialParams(matp) {
    }
    Reference<Texture<Spectrum> > GetSpectrumTexture(const string &name,
            const Spectrum &def) const;
    Reference<Texture<float> > GetFloatTexture(const string &name,
            float def) const;
    float FindFloat(const string &n, float d) const {
        return geomParams.FindOneFloat(n, materialParams.FindOneFloat(n, d));
    }
    string FindString(const string &n, const string &d = "") const {
           return geomParams.FindOneString(n, materialParams.FindOneString(n, d));
    }
    string FindFilename(const string &n, const string &d = "") const {
           return geomParams.FindOneFilename(n, materialParams.FindOneFilename(n, d));
    }
    int FindInt(const string &n, int d) const {
           return geomParams.FindOneInt(n, materialParams.FindOneInt(n, d));
    }
    bool FindBool(const string &n, bool d) const {
           return geomParams.FindOneBool(n, materialParams.FindOneBool(n, d));
    }
    Point FindPoint(const string &n, const Point &d) const {
           return geomParams.FindOnePoint(n, materialParams.FindOnePoint(n, d));
    }
    Vector FindVector(const string &n, const Vector &d) const {
           return geomParams.FindOneVector(n, materialParams.FindOneVector(n, d));
    }
    Normal FindNormal(const string &n, const Normal &d) const {
           return geomParams.FindOneNormal(n, materialParams.FindOneNormal(n, d));
    }
    Spectrum FindSpectrum(const string &n, const Spectrum &d) const {
           return geomParams.FindOneSpectrum(n, materialParams.FindOneSpectrum(n, d));
    }
    void ReportUnused() const {
        geomParams.ReportUnused();
        materialParams.ReportUnused();
    }
    const ParamSet &GetGeomParams() const { return geomParams; }
    const ParamSet &GetMaterialParams() const { return materialParams; }
private:
    // TextureParams Private Data
    map<string, Reference<Texture<float> > > &floatTextures;
    map<string, Reference<Texture<Spectrum> > > &spectrumTextures;
    const ParamSet &geomParams, &materialParams;
};

#endif // PBRT_CORE_PARAMSET_H

redpajama_set_name: RedPajamaGithub


Is it fire? Is it hands? Is it hands caught in a fire? Yes.
Kind of a literal visual interpretation in this week's winning entry, from local graphic designer Brian Cvejanovich, promoting the triple-bill of The Therals, Cymbals Eat Guitars and The Coathangers at the Granada on Sunday night. The word thermal implies heat, heat means fire, blah blah blah, fire goes on the poster.
Simple enough, I guess. But it works, for sure. And the employment of hands into the design adds to the overall appeal, looking, as we said before, like a chorus of folks trapped in a fire reaching for help. Given the Thermals' punk rock appeal, that imagery works well enough, giving it a nice sense of appropriate urgency. Also: Hand-drawn text? Yes, please.
Think you can top this week's winner? Want to see one of your designs get honored? Then go ahead and drop us an email with the image right here.
Oh, and be sure to do so at least a week in advance of the show. Thanks!


text:
Alan Moore's not going to like the new From Hell news
Alan Moore and Eddie Campbell's groundbreaking graphic novel From Hell comes to TV
From Hell, the stunning graphic novel by Alan Moore and Eddie Campbell based on the story of Jack the Ripper, is being developed for TV.
Deadline reports that FX has hired Children Of Men writer David Arata to adapt the doorstop-sized tome for television, while Don Murphy produces.
Johnny Depp as Inspector Frederick Abberline in the film From Hell
Murphy produced the film adaptation from directors Albert and Allen Hughes, which starred Johnny Depp as Inspector Abberline (turned into an opium-taking maverick who sees deaths in drug-fuelled visions) and Heather Graham as Mary Kelly. From Hell the movie did not work, if we're being brutally honest, and we can see TV being kinder to the format of the graphic novel.
Still, it remains to be seen just how much of the sprawling darkness, mysticism and gruesome detail of Moore and Campbell's work makes it into the show, or whether it's simply a Jack the Ripper series with the credibility that comes from adapting a recognised classic.
You can buy From Hell in paperback for £16.99 at Amazon.co.uk. Read more about the comic in our 100 All-Time Greatest Comics bookazine now!
Tags: Alan Moore, From Hell


text:
Inspiring Words from Our Visitors and Members
July 30, 2015 April 10, 2012 by DT Strain
The following are some comments our visitors, guests, and members have made that touched or inspired us. We love hearing from you! If you would like to share your story or thoughts about spiritual naturalism or related topics, please feel free to contact us!
"I think I have finally found an organization with a philosophy that comes closest to how I view the world and how I wish to live my life."
–Gale Iannone
"I just joined SNS as a member. As a spiritual naturalist, it's great to have a place where I can explore all of my interests. I've been known to explore naturalistic interpretations of progressive Christianity, neopaganism, Buddhism, and even Mormonism."
–Dave Salyers
"Spiritual naturalism is the perfect concise description for what I feel on a clear winter night, standing on my porch and looking up at a dark sky filled with stars. It's an overwhelming feeling that almost defies a description at all in mere words…it is, to me, a sacred connection with all that is, has been, and will be."
–Sharon Wells
"I became a supporting member because I believe that unconditional spirituality is found in a Naturalist approach. I also believe that the motto ("happiness through reason and compassion") is the best way to maximize happiness."
–Brooks Park
"Spiritual Naturalism is a broad tent that has a lot to offer. When my belief in the supernatural died, I was thrilled to find ancient philosophies, scriptures, and spiritual paths that were natural, rational, inspiring and life affirming. Ultimately, my faith didn't die – it evolved into something that sustains and keeps me grounded… The creative energy of Life is a sacred and beautiful mystery that connects us all."
–Mark Heisler
"I went to my very first meditation ever two nights ago… Since I de-converted from my Christian Faith in 2011 this was the first time I've had any real spiritual experience in a group setting… tears just flowed down my face. I was finally re-connecting with what resonates within me, a deep sense of connection. Its been so long! I am very thankful to SNS for encouraging us to get involved in such practices…"
–Michelle LeBlanc
"Raised in the south in a mainstream Protestant church, I was taught one truth. As I grew I questioned many things… [Now] I accept whatever background, culture, or faith system I encounter and take from them what is true and meaningful to me… I'm glad to have found this Spiritual Naturalist Society…"
–Martha Perez
"Spiritual naturalism could be called the synergy of rationality, reason and empathy – a human being's most essential tools of survival. It is life positive – human and otherwise."
–Ricky Barnes
"Compassion, love, unity, peace, beauty….that's my spirituality. It's not necessary to believe in an afterlife or a spirit form to feel deeply about things. I'm content with a love for humanity and nature, and respect for science."
–Carla Henderson
"You guys are awesome we really need more people like you doing this throughout not only america but the world."
–Daniel V.
"This looks like something with which I can finally identify… I am a believer in God, but I believe non-believers should have freedom to not believe, in public, and in public forums… Let's all get together and stop being afraid of those who are different."
–Donna Cardinale
"Leaving Christianity and becoming an atheist is a big step. But it isn't the last step. To move forward as a species, we need to learn how to live "the examined life," and live/enjoy life to its fullest. Spiritual naturalism, what some might call a naturalistic "religion without God," is a great way to move forward."
–Truman Smith
"There are many of us atheists who find this present real life –not an afterlife promised by one of the many religions, or another– deeply meaningful, wonderful, and a very rooted grounding for community. We value this world, we appreciate this life, and we believe our fellow creatures on this planet, human & otherwise, are worth the work it will take to make this a better, safer, more just & peaceful planet."
Do you believe in Love?
Some ancient thoughts on divinity can be surprisingly naturalistic when we look to the concepts behind the terms…
How Stoics Treat Jerks
Matt Van Natta explains a commonly under-appreciated aspect of Stoic philosophy – love for others…
The Dire Costs of Ignoring Interconnectedness in 2020
A practical understanding of the challenges of our time…
Naturalism and the Idea of One Mind
The idea that there is the "eternal One," Self, or Universal Mind, of which all individual minds are a part, is an idea that is present in many, perhaps all,
Defined by Something Larger
The adventure in going nowhere…
To acquire or not to acquire, perhaps is not the question…
What can Star Wars teach spiritual naturalists?…
The Centrality of Emotion, Part 2: An Ancient Approach to Modern Science
How can we discover a path that makes emotion genuinely central, but which is also rooted in today's best scientific evidence?


text:
Q: How to download and re-upload a repository? I'm new to using GitHub and most of the resources online are beyond my understanding.
A few years ago I had to commit certain labs and assignments to GitHub, and the repositories were in a "classroom." Forking is disabled on these projects. I don't remember much, other than that we cloned the projects and edited/pushed from Eclipse.
I've long deleted the local copies of the projects I had, and I'm hoping to showcase some of them on my profile. However, even after a few tutorials from GitHub, I don't know how I'm supposed to download the "classroom" repository locally and then re-upload it to GitHub on my own account.
When I download a zip file of a given project, I re-attain a local copy of the project. But when I try to upload it via GitHub desktop, there are issues. I can't upload folders, which is a problem. When I try uploading everything inside the folders, github desktop buffers for ages and doesn't finish the task.
It feels like my question is so basic that I can't find pointers on it, since it's taken for granted that people know how to do this. Any pointers would be hugely appreciated.

A: You should be able to just fork it from the "classroom" repository again if you're just trying to get the original project. Then you can git clone your forked repo.
If that isn't an option you can git clone the "classroom" to your local machine. And create a new repo on your Github where you want the project to eventually be saved. Then go back to the local project you cloned and push the local copy back to your new repo:
git push --mirror  <urlOfYourNewRepo>


In this post we will look at Paul's "therefore" he placed in the passage above. In other words, in Romans 8:1 Paul begins an important summary and conclusion which is related to his preceding arguments. We normally find that argument in the passages directly preceding the "therefore." However, this "therefore" introduces the staggering results of all Paul's teachings in the first seven chapters of Romans, which would include justification by faith alone on the basis of God's overwhelming grace.
What about that word "condemnation"? I heard Steve Furtick sorta preach on this passage once and his usage of this word was that this was that internal voice inside "condemning" us or making us feel guilty for not being "good enough" et cetera. Of course, Furtick and the rest of the emergent's concept of grace is at best confused. The more they try to run from what they call "fundamentalism," the more they find themselves being pinned down by legalism because they reject the clear teaching from God's Word about grace and law. This word is κατάκριμα or katakrima, which means to divide, separate, judge. With the suffix of μα, which we have here, this is actually the result of judgment. This is a condemnatory judgment. It is only found in Romans 5:16, 18, and 8:1. In any case, Paul is telling us here that those in Christ have no condemnation from God. Why?
Why did Jesus, who is God the Son, come in the flesh? It was to bear the sins of those He came to save. He did succeed. This is why there is no condemnation for those in Christ Jesus. Paul makes some very interesting statements in this passage. Those truly in Christ walk not according to the flesh, but according to the Spirit. After that he makes comparisons. Paul is talking about the mind-set of those in Christ in comparison to those who are not. The regenerate have a different set of affections, mental processes and direction of the will than the natural man. The unbeliever's basic disposition is to satisfy the cravings of their unredeemed flesh. Those whose minds are set on the flesh are hostile to God because they are spiritually dead, therefore, those truly in Christ have minds that are not set on the flesh and they are not hostile to God because they have been baptized into Christ and belong to Him.
As I listen to the emergents give their reasons for their theology of unbelief and Christian agnosticism, I know that they would simply scoff at this study and say that I am just a Biblical literalist and we have no ability to really understand the Bible. Well, you know, if in fact the Spirit of God dwells in you, then you are not in the flesh, but in the Spirit and that means that He will guide you into all truth and help you to see and understand God's Word. When I see these people try to say they are the real "christians" who doubt and are full of unbelief and we are all a bunch of legalists because we can read and understand God's Word, teach it and preach it, then I know that what we are dealing with there are people who are desperately religious, but they do not know my Lord nor does His Spirit dwell in them because, if He did, they would understand and see.
This entry was posted in Christian Authenticity, Grace, Law and Gospel, Religion, Sanctification. Bookmark the permalink.


text:
Q: Locking mutex in one thread and unlocking it in the other Will this code be correct and portable?
void* aThread(void*)
{
    while(conditionA)
    {
        pthread_mutex_lock(mutex1);
        //do something
        pthread_mutex_unlock(mutex2);
    }
}

void* bThread(void*)
{
    while(conditionB)
    {
        pthread_mutex_lock(mutex2);
        //do something
        pthread_mutex_unlock(mutex1);
    }
}

In the actual application I have three threads - two for adding values to an array and one for reading them. And I need the third thread to display the contents of the array right after one of the other threads adds a new item.

A: As user562734's answer says, the answer is no - you cannot unlock a thread that was locked by another thread.
To achieve the reader/writer synchronisation you want, you should use condition variables - pthread_cond_wait(), pthread_cond_signal() and related functions.

A: It is not. If thread A gets to mutex_unlock(2) before thread B got to mutex_lock(2), you are facing undefined behavior. You must not unlock another thread's mutex either.
The pthread_mutex_lock Open Group Base Specification says so:

If the mutex type is PTHREAD_MUTEX_NORMAL [...] If a thread  attempts  to  unlock  a mutex that it has not locked or a mutex which is unlocked, undefined behavior results.

A: Some implementations do allow locking and unlocking threads to
be different.
#include <iostream>
#include <thread>
#include <mutex>

using namespace std;

mutex m;

void f() {m.lock();   cout << "f: mutex is locked" << endl;}

void g() {m.unlock(); cout << "g: mutex is unlocked" << endl;}

main()
{
      thread tf(f);    /* start f                           */
      tf.join();       /* Wait for f to terminate           */
      thread tg(g);    /* start g                           */
      tg.join();       /* Wait for g to terminate           */
}

This program prints
f: mutex is locked
g: mutex is unlocked
System is Debian linux, gcc 4.9.1. -std=c++11.