text:
These were the worst passwords of 2017
Avoiding common cybersecurity pitfalls can help keep your information safe
Sarah D. Young Reporter and Editor
Photo (c) designer491 - Getty Images
From data breaches to fraudulent activity, 2017 saw a number of scary threats to consumers' security. And although 2018 has just begun, two critical cybersecurity exploits have already unfolded, putting consumers personal information at risk.
In order to keep your sensitive personal information from falling into the wrong hands, it's crucial to make sure you have a strong password in place on electronic devices, including tablets, smartphones, and computers.
However, a recent study suggests consumers tend to favor convenience over security when it comes to picking a password.
Worst passwords
These were SplashData's top 10 worst passwords from 2017, according to NextAdvisor.
letmein
Common password pitfalls
In an interview with ConsumerAffairs, Jocelyn Baird, associate editor at NextAdvisor, pointed out that half the list is made up of strings of ascending numbers.
"This tells us that when people are faced with the need to create a password with a minimum of, for example, six characters, a lot will simply opt for the easiest possible choice and type in '123456.' Those are as lazy as you can get, but the other passwords on the list don't fare much better," Baird said.
Many consumers chose login-related passwords (such as "admin" or "passw0rd"), while others opted for a single word that likely had something to do with their life or interests (such as "Andrea" or "starwars").
Choosing a safe password
In an age where consumers are required to choose a password for everything from their computer at work to their bicycle lock, password fatigue has become a very real problem. Baird noted that the average person has well over ten online accounts.
While it may be tempting to choose the same simple, easy-to-remember password for all your accounts, security experts don't recommend doing so.
"In general, you're better off using more variety and characters. A combination of uppercase and lowercase letters, numbers and special characters (e.g., # or !) is the way to go," Baird said. "And don't forget that when it comes to passwords, longer is stronger."
A password manager can help you keep track of all of your passwords. Check out ConsumerAffairs' list of the best options here.
Additional security measures
In addition to making sure all of your passwords contain the above-mentioned attributes, be sure to utilize all the security options that are available to you.
"Remember, all it takes is one compromised password to unlock your entire network of accounts – especially if you're using the same password for more than one account," Baird said.
For an added security boost, she recommends the following:
Use two-step verification. Also known as two-factor authentication (or TFA), this security measure requires a second piece of information besides your password to get logged in. "Usually, this second data point is a specially generated, one-time code sent to you via SMS, email, or through a phone call," Baird said.
Set a lock code. To ensure no one can pick up your phone and use it or see its contents, be sure to set a lock code. "These vary from smartphone to smartphone, but can range from a four- to six-digit PIN to a 'knock code' created by a specific pattern of taps on your screen to biometrics (e.g., your fingerprint)," Baird said.
Be mindful of connections. "Free Wi-Fi from your local coffee shop might seem like a sweet deal, but hackers could be lurking on the network looking for unsuspecting victims," Baird said.
Sarah D. Young
Sarah has been writing and editing for ConsumerAffairs since 2015. Her areas of interest include technology and cybersecurity news, retail news, and home and living news. She is a graduate of Virginia Commonwealth University, an interior design enthusiast, and a mother of two.
Creating strong passwords helps protect consumers against hackers
The worst passwords of 2018
Twitter users urged to change their passwords
Which devices are most vulnerable to cyberattack?
Apple operating systems vulnerable to password theft
Man who created modern password management rules says he was largely mistaken


text:
Q: When downloading MNIST, I can't get the "processed" folder I am following a tutorial in here https://www.youtube.com/watch?v=IQpP_cH8rrA
I followed all the initial steps (except I am in VS not in Colab) but I stop pretty soon because when running:
torchvision.datasets.MNIST('./', download=True)

I get only the raw folder, not the processed one (which should contain training.pt and test.pt).
Can anybody help?
I am running on python 3.8.10, torch version 1.10.1, torchvision 0.11.2
PS: I found the same issue here https://github.com/pytorch/vision/issues/4685
should I really downgrade torchvision to 0.9.1 to have both folders?
if yes, how can I just downgrade torchvision from cmd, without uninstall torch and install everything back?

A: I found this work around, downloading the data from tensorflow and then just switching the data types so you can follow along the tutorial again. hope this helps
import tensorflow as tf
import torch
import numpy as np

mnist = tf.keras.datasets.mnist

(x_train, y_train), (x_test, y_test) = mnist.load_data()

print(x_train.shape)
images = torch.from_numpy(x_train)
ground_truth = torch.from_numpy(y_train)
print(images.shape)
print(ground_truth.shape)

`
This works in my notebook, hopefully it does for you too

A: I am not sure if this answer will help anyone but this was my solution to it (after lots of trying and searching in the internet, I am not too experienced):
(I used anaconda prompt)

*

*I created a virtual environment called "test" for python 3.6:
conda create -n test python=3.6
activate test

*I installed the recommended torchvision version on it:
pip install torchvision==0.9.1

*I ran my program in the virtual environment:
python yourprogram.py

I am sure this is not the best solution to exist but it worked for me and was very easy as it is just a few lines in anaconda prompt.

redpajama_set_name: RedPajamaStackExchange


Katalor have supply en 10155 s235j0w corten steel with shear edges suppliers and manufacturer ,if you need supply en 10155 s235j0w corten steel with shear edges price and specification ,please contact us.
We mainly supply what is EN S355J2G2W corten steel with shear edges,Corten A, A588 Grade A, A588 Grade B, A588 Grade C, A588 Grade K,S235J0W, S355J0WP, 09CuPCrNi-A,S355J0W,Q355GNH, Q355NH, SPA-H,A242 Type 1, S355J0WP, S235J0W, Q460NH, Q295NH Weather Resistant Steel Plate stock,looking forward to our cooperation.
We mainly supply EN 10155 S355J0W anti weathering corrosion 4mm steel plate with shear edges,Corten A, A588 Grade A, A588 Grade B, A588 Grade C, A588 Grade K,S235J0W, S355J0WP, 09CuPCrNi-A,S355J0W,Q355GNH, Q355NH, SPA-H,A242 Type 1, S355J0WP, S235J0W, Q460NH, Q295NH Weather Resistant Steel Plate stock,looking forward to our cooperation.
BBN Steel mainly export EN 10155 S355J0WP weather proof 2mm steel plate with shear edges,Corten A, A588 Grade A, A588 Grade B, A588 Grade C, A588 Grade K,S235J0W, S355J0WP, 09CuPCrNi-A,S355J0W,Q355GNH, Q355NH, SPA-H,A242 Type 1, S355J0WP, S235J0W, Q460NH, Q295NH weather resistant steel plate stock for you,looking forward to our cooperation!
We mainly supply what is EN 10025 5 corten steel with shear edges,Corten A, A588 Grade A, A588 Grade B, A588 Grade C, A588 Grade K,S235J0W, S355J0WP, 09CuPCrNi-A,S355J0W,Q355GNH, Q355NH, SPA-H,A242 Type 1, S355J0WP, S235J0W, Q460NH, Q295NH Weather Resistant Steel Plate stock,looking forward to our cooperation.


Reducing systems include a microbial consortium, chemically-reduced vitamin B12, biologically-reduced vitamin B12, and a consortium amended with vitamin B12. We are separately evaluating the reduction of the catalyst and the transformations of chlorinated organic compounds. 2,3,4,5,6-Pentachlorobiphenyl (2,3,4,5,6-PCB) was selected as the model chlorobiphenyl for study because one ring is fully chlorinated. Other model compounds (for comparison) include the chlorinated phenols and chlorinated methanes. The project is being conducted in two concurrent parts: (1) evaluation of the microbial reduction of vitamin B12 and (2) evaluation of the transformations mediated by vitamin B12.


text:
Three Baltimore hotels win TripAdvisor 2013 Travelers' Choice awards
By By Michelle Deal-Zimmerman and The Baltimore Sun
Rachael's Dowry in Ridgely's Delight is among the Top 10 U.S. bed and breakfasts, according to TripAdvisor. (Kim Hairston, Baltimore Sun)
TripAdvisor has announced the winners of its 2013 Travelers' Choice awards for lodging and three Baltimore hotels are among those recognized by the travel website.
The awards are based on millions of reviews and feedback from travelers who rated more than 650,000 hotels in categories of Top Hotels, Luxury, Service, Small Hotels, and B&Bs and Inns.
The Inn at The Black Olive, where TV stars such as Julia Louis Dreyfus reportedly have stayed, was ranked third among U.S. properties in the Small Hotel category. The 12-room Fells Point property owned by the Stelios family and known for its eco-friendly amenities was also no. 14 among U.S. hotels with the best service.
Rachael's Dowry Bed and Breakfast was named among the Top 10 B&Bs in the U.S. The hotel, located in a restored 8,000-square-foot mansion in Ridgely's Delight, was ranked no. 6. Other regional B&Bs at the top of the list include Stony Point B&B in Tyrone, Pa. (no. 3); Albert Stevens Inn in Cape May, N.J. (no. 5) and Piney Hill B&B in Luray, Va. (no. 7). The top B&B was Point Clear Cottages in Fairhope, Ala.
The Four Seasons Baltimore, which opened in late 2011, came in at no. 18 on the list of top U.S. luxury hotels. The Harbor East hotel offers more than 250 lavish rooms, including 45 suites, including The Royal Suite, which is 2,800 square feet, with a marble foyer, office, media room, dressing room and service pantry with stainless-steel appliances. Luxe and lush, indeed.
The Four Seasons Resort Hualalai at Historic Ka'upulehu in Kailua-Kona, Hawaii, took top honors overall, garnering awards for the top hotel in the U.S. and the world as well as the top luxury hotel.
Overall there were more than 6,000 award-winning properties in 82 countries and in nine regions across the globe. This is the 11th year for TripAdvisor's Traveler Choice Awards.
michelle.deal@baltsun.com
Hotel and Accommodation Industry
Transportation Industry
Most Read • Travel
Essential Ocean City: 50 things every visitor must experience

redpajama_set_name: RedPajamaCommonCrawl


The right employees who are trained, knowledgeable, and fit well into the cohesion of your company can be hard to find. There are so many factors that go into finding the right person to do an important job, and the task of recruiting someone new can seem daunting in such an expansive job market.
When it comes to the security of your business however, finding top IT talent on your team is worth the search, because you can't afford to make a bad hire. Hiring a qualified IT security specialist is one of the most important things you can do to ensure that your business is safeguarded against cyber theft and data breaches, and protect the integrity of your entire company. Here are some strategies for how you can find these IT security specialists, and recruit them for your business.
The nature of the tech business means that trends are constantly changing and evolving, even on a month-to-month basis. If you haven't hired an IT specialist in a while, it might be a good idea to research the newest software being used in IT security. If you're familiar with the lingo and newest tech developments, it will be easier for you to be able to tell what your potential new hire's skills are. Reading security tech blogs that update regularly, subscribing to technical magazines, and keeping up to date on social media are just a few ways you can ensure that you are asking the right questions and implementing the right strategies to hire someone skilled and knowledgeable.
Making sure that your candidate is properly qualified for the job is one of the most important steps in the hiring process. However, unless you're an expert in the IT security field, it can be hard to know what to look for in terms of credentials when starting to look for your new employee. An ideal certification for your potential hire ensures that your candidate has proven deep technical and managerial competence, design credibility, and overall knowledge of security programs to protect your business from growing technical attacks.
Looking for candidates with certifications like CISSP, SSCP, ISSEP, ISSAP, ISSMP, CISA, CISM, CCSP, GESC, and CISO will narrow down your choice to who is most qualified to become the newest member of your team.
If you've already started on the hunt for a qualified IT security specialist, you might know that there is currently an IT skills shortage. With computers taking the workplace by storm in recent years, every company needs a skilled Information Technology expert to keep their business's digital networks running smoothly and efficiently. This means that many of the best IT professionals have already been snatched up by other businesses, making navigating the job market a tough and daunting task.
However, an IT recruitment firm can help steer you through the difficult hiring process, and provide you with advice for who the best candidate is to suit your company's needs. Not only do recruitment firms know the best ways to go about recruiting elusive IT security talent, oftentimes the best candidates seek the services of an IT recruitment agency, too. Top candidates know how important it is to find a company that is best suited for their skill set, and working with an agency will make the job of finding these companies easier and more efficient. Pairing up with the right recruitment firm will help both you and your future IT security hire find each other without all the stress and uncertainty that often comes with the staffing process.
Simon is a branch manager at Inteqna. With over 15 years of experience in the business-to-business sphere and 10 years of experience in IT recruitment, no recruiting assignment is impossible for this master multi-tasker. Simon keeps up to date on the most popular social media channels and recruiting tools in pursuit of satisfying each and every customer. Simon sees himself as a dreamer like John Lennon, which is why he's a fan of all new tech-like applications, such as big data, artificial intelligence, the Internet of Things, and virtual reality.


In this shortest video you can learn to make khatti meethi Imli chatni with in 5 minutes with tips. this is a perfect chatni with pakodas , bhujias , snacks , idli sambhar. Sweet and tangy tamarind is one of the widely used condiment spices found in every Indian kitchen. Tamarind is rich in tartaric acid. Tartaric acid gives a sour taste to food but is also a very powerful antioxidant. It helps the body protect from harmful free radicals. This prized spice is a good source of minerals like copper, potassium, calcium, iron, selenium, zinc and magnesium. In addition, it is also rich in many vital vitamins, including thiamin, vitamin A, folic acid, riboflavin, niacin, and vitamin-C. So enjoy Imli chatni & share your comments with me.
Wash imli and boil in water. Cool it. Mash and sieve by adding little water.mix all the pices.
If sour , add more sugar.


text:
Graduates plan for their futures and reflect on their time at UAA
Graduation is right around the corner at UAA. The commencement ceremony will include the chancellor's address, the student speaker, the ceremonial presentation of degrees and students receiving their diplomas on stage.
Throughout their time at UAA, nearly every student faced challenges at some point on their academic journey. Some changed majors, others faced financial strains.
Senior Gina Hays, journalism and public communications major, plans to complete her graduate studies out of state, then return to Alaska to find a career. Photo by Christina Swayney.
Gina Hays is graduating with a degree in journalism and public communications, and said her UAA experience surprised her in many ways.
"I have met some of the greatest people and some of the greatest professors at the university. I have learned so much about Alaska and it has given so much respect for where I live, and it has inspired me to stay in my state," Hays said.
Hays hopes to return to Alaska after continuing her studies out of state.
"I really want to go into political communications in graduate school. It's something I really look forward to doing," Hays said.
Senior Veronica Hoxie, a journalism and public communications major, is looking forward to exploring communications roles and careers with local companies after graduation. Photo courtesy of Veronica Hoxie.
Veronica Hoxie, also a journalism major, is excited to graduate as well. She said her overall college experience was great, but wishes that there were more options in class schedules for students who are also working and/or parents.
"[Class schedule times are] not extremely accommodating for working parents. It would be great if there were more class options for working parents, especially since it is one of the only university options in the state. That would be great so that they can work, be a parent and pursue an education at the same time," Hoxie said.
Hoxie plans to move into a communications role with a local company after graduating.
Senior Tammalivis Salanoa, a digital arts major, plans to continue her work as a volunteer in the Anchorage community after graduation through completing an internship at the Anchorage Museum. Photo courtesy of Tammalivis Salanoa.
Tammalivis Salanoa, a digital art major, is the public relations director for the Union of Students at UAA, or USUAA. Salanoa is very active in the UAA and Anchorage communities and is looking forward to staying present in the state.
"My plans for after college are to stay active in the local community through volunteerism. I also am currently working at the Anchorage Museum as an intern in their education department. I plan to build up my art portfolio and refine my style as an artist," Salanoa said.
The 2019 fall commencement will take place on Dec. 15 from 1-3 p.m. at the Alaska Airlines Center. Tickets are not required for the ceremony, although each graduating student is allotted five tickets.
For more information about tickets or the ceremony, visit the UAA Commencement webpage.
Previous articleUAA | University Art Analysis — 'Stellar Mitosis' sheds light on the sciences
Next articleSeawolf athletics set to lose many talented student-athletes as 2019-2020 graduates
Hitbox First Impressions: Ring Fit Adventure — It's not just exercise,...
Ring Fit Adventure is a little difficult to categorize. Is it a game or exercise software? Well, it's a mix of both, but definitely...
UAA | University Art Analysis — A steel sculpture helps students...


We think you should have a choice when it comes to the Operating System that runs your network. The Vault is ready to run whatever you throw at it.
No fans and no noise. The Vault's solid Aluminium chassis means you can deploy your firewall on your desk and still hear yourself think. Plus, the absence of moving parts means there are no fans to replace, or spinning disk drives to worry about failing.
At just 5 x 5 x 1.5 inches, the Vault packs a punch for such a small device. Plus, it sips power, running at only around 10W.


A beautifully presented recently developed one bedroom apartment. Fully fitted kitchen with all appliances integrated. Luxury bathroom with power shower. Good sized sitting room. Parking. Outside cycle store. Central location. Available now.


text:
Aircraft Debris Found in New York Reservoir After Plane Disappears
Published Nov 20, 2015 at 6:47 AM | Updated at 10:19 AM EST on Nov 20, 2015
NBCConnecticut.com
Crews are searching for a missing plane.
Search crews combing the waters of a New York reservoir for a plane that went missing on approach to an airport in Connecticut have found debris thought to be from the missing craft, state police said.
A seat and wheels thought to be from the missing Cessna were found in the Titicus Reservoir near Salem, New York, on Friday morning. The discovery comes less than a day after a plane set to land at the Danbury Airport in Connecticut went missing.
Authorities lost contact with the Cessna at about 4 p.m. Thursday; it had departed Mississippi earlier in the day. Its last known location is near the reservoir, which supplies water to New York City.
Authorities said there is no threat to the water supply, but hazmat teams are at the site as a precaution.
Top News: Puerto Rico Protests Continue
Eric Rojas/AFP/Getty Images
Search boats and divers could be seen scouring the reservoir Thursday and Friday. The search was suspended overnight due to thick fog that settled over the body of water.
Crews said they're continuing to search the river.
Contact Tracie Strahan
Twitter, Facebook, Email


text:
Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities
Zoltan Dekan, Stephen J. Headey, Martin Scanlon, Brian A. Baldo, Tzong-Hsien Lee, Marie-Isabel Aguilar, Jennifer R. Deuis, Irina Vetter, Alysha G. Elliott, Maite Amado, Matthew A. Cooper, Dianne Alewood, Paul F. Alewood
Δ-Myrtoxin-Mp1a (Mp1a), a 49-residue heterodimeric peptide from the venom of Myrmecia pilosula, comprises a 26-mer A chain and a 23-mer B chain connected by two disulfide bonds in an antiparallel arrangement. Combination of the individual synthetic chains through aerial oxidation remarkably resulted in the self-assembly of Mp1a as a homogenous product without the need for directed disulfide-bond formation. NMR analysis revealed a well-defined, unique structure containing an antiparallel α-helix pair. Dual polarization interferometry (DPI) analysis showed strong interaction with supported lipid bilayers and insertion within the bilayers. Mp1a caused non-specific Ca2+ influx in SH-SY5Y cells with a half maximal effective concentration (EC50) of 4.3 μm. Mp1a also displayed broad-spectrum antimicrobial activity, with the highest potency against Gram-negative Acinetobacter baumannii (MIC 25 nm). Intraplantar injection (10 μm) in mice elicited spontaneous pain and mechanical allodynia. Single- and two-chain mimetics of Mp1a revealed functional selectivity.
Angewandte Chemie - International Edition
https://doi.org/10.1002/anie.201703360
antimicrobial peptides
nociceptive pain
10.1002/anie.201703360
Dekan, Z., Headey, S. J., Scanlon, M., Baldo, B. A., Lee, T-H., Aguilar, M-I., Deuis, J. R., Vetter, I., Elliott, A. G., Amado, M., Cooper, M. A., Alewood, D., & Alewood, P. F. (2017). Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities. Angewandte Chemie - International Edition, 56(29), 8495-8499. https://doi.org/10.1002/anie.201703360
Dekan, Zoltan ; Headey, Stephen J. ; Scanlon, Martin ; Baldo, Brian A. ; Lee, Tzong-Hsien ; Aguilar, Marie-Isabel ; Deuis, Jennifer R. ; Vetter, Irina ; Elliott, Alysha G. ; Amado, Maite ; Cooper, Matthew A. ; Alewood, Dianne ; Alewood, Paul F. / Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities. In: Angewandte Chemie - International Edition. 2017 ; Vol. 56, No. 29. pp. 8495-8499.
@article{743ec3c5856746b185c8743b7c7d868d,
title = "Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities",
abstract = "Δ-Myrtoxin-Mp1a (Mp1a), a 49-residue heterodimeric peptide from the venom of Myrmecia pilosula, comprises a 26-mer A chain and a 23-mer B chain connected by two disulfide bonds in an antiparallel arrangement. Combination of the individual synthetic chains through aerial oxidation remarkably resulted in the self-assembly of Mp1a as a homogenous product without the need for directed disulfide-bond formation. NMR analysis revealed a well-defined, unique structure containing an antiparallel α-helix pair. Dual polarization interferometry (DPI) analysis showed strong interaction with supported lipid bilayers and insertion within the bilayers. Mp1a caused non-specific Ca2+ influx in SH-SY5Y cells with a half maximal effective concentration (EC50) of 4.3 μm. Mp1a also displayed broad-spectrum antimicrobial activity, with the highest potency against Gram-negative Acinetobacter baumannii (MIC 25 nm). Intraplantar injection (10 μm) in mice elicited spontaneous pain and mechanical allodynia. Single- and two-chain mimetics of Mp1a revealed functional selectivity.",
keywords = "antimicrobial peptides, nociceptive pain, peptides, self-assembly, toxins",
author = "Zoltan Dekan and Headey, {Stephen J.} and Martin Scanlon and Baldo, {Brian A.} and Tzong-Hsien Lee and Marie-Isabel Aguilar and Deuis, {Jennifer R.} and Irina Vetter and Elliott, {Alysha G.} and Maite Amado and Cooper, {Matthew A.} and Dianne Alewood and Alewood, {Paul F.}",
doi = "10.1002/anie.201703360",
journal = "Angewandte Chemie - International Edition",
Dekan, Z, Headey, SJ, Scanlon, M, Baldo, BA, Lee, T-H, Aguilar, M-I, Deuis, JR, Vetter, I, Elliott, AG, Amado, M, Cooper, MA, Alewood, D & Alewood, PF 2017, 'Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities', Angewandte Chemie - International Edition, vol. 56, no. 29, pp. 8495-8499. https://doi.org/10.1002/anie.201703360
Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities. / Dekan, Zoltan; Headey, Stephen J.; Scanlon, Martin; Baldo, Brian A.; Lee, Tzong-Hsien; Aguilar, Marie-Isabel; Deuis, Jennifer R.; Vetter, Irina; Elliott, Alysha G.; Amado, Maite ; Cooper, Matthew A.; Alewood, Dianne; Alewood, Paul F.
In: Angewandte Chemie - International Edition, Vol. 56, No. 29, 10.07.2017, p. 8495-8499.
T1 - Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities
AU - Dekan, Zoltan
AU - Headey, Stephen J.
AU - Scanlon, Martin
AU - Baldo, Brian A.
AU - Lee, Tzong-Hsien
AU - Aguilar, Marie-Isabel
AU - Deuis, Jennifer R.
AU - Vetter, Irina
AU - Elliott, Alysha G.
AU - Amado, Maite
AU - Cooper, Matthew A.
AU - Alewood, Dianne
AU - Alewood, Paul F.
N2 - Δ-Myrtoxin-Mp1a (Mp1a), a 49-residue heterodimeric peptide from the venom of Myrmecia pilosula, comprises a 26-mer A chain and a 23-mer B chain connected by two disulfide bonds in an antiparallel arrangement. Combination of the individual synthetic chains through aerial oxidation remarkably resulted in the self-assembly of Mp1a as a homogenous product without the need for directed disulfide-bond formation. NMR analysis revealed a well-defined, unique structure containing an antiparallel α-helix pair. Dual polarization interferometry (DPI) analysis showed strong interaction with supported lipid bilayers and insertion within the bilayers. Mp1a caused non-specific Ca2+ influx in SH-SY5Y cells with a half maximal effective concentration (EC50) of 4.3 μm. Mp1a also displayed broad-spectrum antimicrobial activity, with the highest potency against Gram-negative Acinetobacter baumannii (MIC 25 nm). Intraplantar injection (10 μm) in mice elicited spontaneous pain and mechanical allodynia. Single- and two-chain mimetics of Mp1a revealed functional selectivity.
AB - Δ-Myrtoxin-Mp1a (Mp1a), a 49-residue heterodimeric peptide from the venom of Myrmecia pilosula, comprises a 26-mer A chain and a 23-mer B chain connected by two disulfide bonds in an antiparallel arrangement. Combination of the individual synthetic chains through aerial oxidation remarkably resulted in the self-assembly of Mp1a as a homogenous product without the need for directed disulfide-bond formation. NMR analysis revealed a well-defined, unique structure containing an antiparallel α-helix pair. Dual polarization interferometry (DPI) analysis showed strong interaction with supported lipid bilayers and insertion within the bilayers. Mp1a caused non-specific Ca2+ influx in SH-SY5Y cells with a half maximal effective concentration (EC50) of 4.3 μm. Mp1a also displayed broad-spectrum antimicrobial activity, with the highest potency against Gram-negative Acinetobacter baumannii (MIC 25 nm). Intraplantar injection (10 μm) in mice elicited spontaneous pain and mechanical allodynia. Single- and two-chain mimetics of Mp1a revealed functional selectivity.
KW - antimicrobial peptides
KW - nociceptive pain
KW - peptides
KW - self-assembly
KW - toxins
U2 - 10.1002/anie.201703360
DO - 10.1002/anie.201703360
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
Dekan Z, Headey SJ, Scanlon M, Baldo BA, Lee T-H, Aguilar M-I et al. Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities. Angewandte Chemie - International Edition. 2017 Jul 10;56(29):8495-8499. https://doi.org/10.1002/anie.201703360


Dutch multipurpose specialist Spliethoff has integrated 'nauticAi Map' mapping service into its sensor-based fleet performance platform.
Dutch shipping company Spliethoff has signed a deal with AST Marine Networks, a division of The AST Group (AST), to supply global VSAT and L-band satellite communications to approximately 80 vessels across its multiple fleets.
Dutch shipping company Spliethoff has agreed a deal with Raytheon Anschütz for the delivery of integrated navigation systems (INS) to six newbuild ice-classed multi-purpose vessels.


This Dog Warning Sign checks potential criminals from entering your private property.
• Bright and attractive, the sign cannot be missed.
• Premium material is used to construct the sign that ensures durability.
Very sturdy, well made. Excellent craftsmanship.
Excellent quality but for the money, it should be. That being said, it was a fair price for what I received. Would buy again if I wanted to get a sign that will last longer than me!! Shipping was fast and product arrived in good shape.


Pennington's girls' swim team took second place in the NJISAA Prep B swim championships held on February 6. The Red Raiders missed out on a first place finish by a mere 1.5 points.
Jenna Kollevoll, Mina Shokoufandeh, Alex Stevens and Ellie Schinsky created one of the big highlights at the meet when they swam together in the 200 yard medley relay. The four swimmers ended up setting a new Pennington School record, new meet record and new pool record!
Details of today's racing will be posted once all results have been finalized.


A non-governmental organisation (NGO) committed to addressing poverty by working in partnership with the communities that we serve to build sustainable, healthy and productive communities in Uganda.
To help some of the poorest families in Uganda by providing a platform to help themselves out of poverty.
We seek to address poverty and destitution faced by many communities in Uganda by implementing 'grassroots' solutions to local challenges in an effort to help people help themselves. We work alongside communities to find practical solutions to the poverty they face and work to provide for their physical, spiritual and emotional needs. We actively seek to work with communities and adopt a collaborative approach, sharing knowledge and experience.
Putting communities first – Our sustainable agriculture enterprises are people centred. We focus on providing support on what matters most to the people we serve, respects their rights, beliefs, abilities and needs, and supports their own efforts to enrich the quality of their lives and break the barrier that poverty poses.
Forging Partnerships – Communities living in poverty are partners in their own development. We provide the catalyst to help them access information and knowledge. We promote a communal and collaborative model of service that fosters a sense of ownership, pride and participatory development among the communities that we serve.
Conserving for future generations – All projects are implemented with environmental conservation and sustainable development as the principle goal. All projects aim to be sustainable – economically, environmentally, socially and institutionally.
The prevention or relief of poverty in Central Uganda, Africa by providing: grants, items and services to individuals in need and/or charities, or other organisations working to prevent or relieve poverty.


text:
Home / Appointments / Compass strengthens executive team
(l-r) Charlie Brown, Sarah Sergeant and Ian Cranna
Compass strengthens executive team
Posted by: Sarah OBeirne in Appointments, Business, Contract wins and partnerships, Contracts, Facilities Management, Food services, News February 18, 2020	1,879 Views
Food and support services company, Compass Group UK & Ireland, has bolstered its executive team with a number of key appointments.
Ian Cranna has been appointed to the role of Chief Marketing Officer. Cranna joins the business from Starbucks and has over 25 years' experience working for major retail and food and beverage brands.
Charlie Brown has been appointed Managing Director of Chartwells, the company's education business, following the departure of Richard Taylor at the end of January. Most recently Compass UK's Transformation Director, Brown has held senior operational roles across a number of Compass sectors including Chartwells and was Managing Director for its Government Services and 14Forty businesses. Prior to joining Compass, he was at Whitbread for 10 years.
Also joining the UK & Ireland executive team as Finance Director is Sarah Sergeant, who takes over from Kate Dunham, interim Finance Director and has been in the Compass family for over 12 years, most recently as Financial Controller for Compass Group Plc. Prior to this Sergeant worked as the company's Chief Financial Officer for Asia Pacific. She has a strong finance background having spent the first nine years of her career at Price Waterhouse Cooper.
Commenting on the appointments Robin Mills, Managing Director of Compass Group UK & Ireland said: "Compass' key strength is its brilliant people and I'm delighted to welcome Ian to the Compass family and congratulate Charlie and Sarah on their appointments. We have an exciting year ahead of us and these new appointments will be integral as we drive Compass forward on its growth journey and shape our future business strategy."
Your free ticket to Facilities Show 2020
Join 12,000+ of your FM peers from across the world at ExCeL London on 19-21 May. Bring the team and boost your CPD, your skills and your career with seminars and workshops at the only IWFM- supported exhibition. Test, trial and source smart solutions across technology, cleaning, FM services, waste and energy management; and meet a host of suppliers for new business collaborations. Your ticket also gives you free access to co-located shows to boost your specialisms across wellbeing, smart buildings, fire, security and health & safety.
Get your free ticket for Facilities Show.
Sarah OBeirne
Previous: ECOOS II redefines light radiating 360 degrees from a single source
Next: CIBSE Building Performance Awards 2020 winners
About Sarah OBeirne


TripAdvisor - Forest view condo w/ deck, shared hot tub/seasonal pool - steps to the Village!
Hot Tub - Forest view condo w/ deck, shared hot tub/seasonal pool - steps to the Village!
Forest view condo w/ deck, shared hot tub/seasonal pool - steps to the Village!


Sanctuary... a place of refuge providing safety from those who would bring you harm. Sometimes those who seek sanctuary are not those who you would expect to do so. Even the blackest heart needs someplace that they can call home.
The rural backwater of Cherrimoor is a place far from the political intrigue of the towns and cities but it has its own stories. A Gothic adventure unfolds, involving a search for a fallen paladin, a family curse and the new tenant of Tharlin Keep.
Sanctuary is a role-playing game for 4-6 characters of levels 4-5. It includes a detailed local setting, maps and core plotline that can be used with most d20 fantasy games and comes with a bonus CD containing Music Tracks, key scenes, and building rendered in 3D.


We've completed the kirkwood ski tickets discount satellite.
Also, for anyone who has watched and waited for a how to convert amazon gift card into paypal rocket launch (think about space shuttle missions) sometime there are delays from things like weather, equipment malfunction, electronics issues, etc.
Every dollar over the 33,000 means that our tardis can be a little bit bigger.
Yeah, so.Daily Faction Rally Milestone Public events Lost Sectors Strikes Nightfall Strikes Clearing the Raid Crucible Trials of the Nine Once youve amassed enough faction tokens, turning them into a vendor will reward you with a Faction Engram full of loot.The site will also have all of the information that is stored on the tardis's SSDs. All we have to do is raise the money to pay for our ticket as it were.The second Faction Rally runs all the way up to 11th June 2018 and ends at the same times posted above.Your Milestones will also be updated with a faction specific task.
This system returns in Destiny 2, giving Guardians the chance to fight for their faction and get their hands on some of the most sought-after gear in the game.
The bigger it is, the more space it takes up inside the rocket.
You may not know this, but rockets are really expensive!With this in mind, it's wise to use up all your tokens before the end of the week.We will also post images taken from the tardis itself - pictures from space.Renown is lost when players are defeated by enemies, so be careful when you're attempting to loot a Lost Sector with high Renown!The antenna does not properly deploy and the satellite cannot transmit images.Now we just need the money to put our satellite into the rocket.Faction Rally: When does it go live?The 2013 launches are dedicated, and the manifests are filling.
Lastly, in 1 Peter 4:10-11, Peter tells the discount tire silverthorne church that he has noticed their spiritual giftedness of speaking and serving.Jesus Christ plundered Satans primary games vol 3 spin win kingdom by His death, rescued our giftedness from Satan, and now..
Schließen, beginn eines Dialogfensters, einschließlich Registerkartennavigation, um ein Konto zu registrieren oder sich bei einem bestehenden Konto einzuloggen.Sowohl für die Registrierung als auch zum Einloggen können Google- und Facebook-Konten verwendet werden.My Current Location gJgE6qllsc1EE2_ml.Mit der Escape-Taste kann das Fenster geschlossen werden.Skip to content..


text:
Q: Morphism that conserve sums Let $\{ a_i \}_{1,n} \in \mathbb{(R⁺)}^n$  verifying $\sum_i a_i = 1$ and $a_1 < a_2 < \dots < a_n$.
Is there any function (or family of function) $f$ that verifies :

*

*$\sum_i f(a_i) = 1$

*$f(a_1) > f(a_2) > \dots > f(a_n$)

?
If there is, can you give an exemple. If not, why ?
From 2., I know that f is decreasing over $\mathbb{R⁺}$ but I can't find any of those functions...

A: We have such functions only for each $\ n>1\ $ separately but not any function which would work for any two different values of $n>1$ at the same time.
For each natural $\ n>1,\ $ such function
$$ f_n : \mathbb R_+\rightarrow \mathbb R\ $$
is unique; here $\ \mathbb R_+\ $ can be interpreted as $\ (0;\infty)\ $ or $\ [0;\infty),\ $ either way.

For $\ n>1,\ $ we let
$$\ f_n(x) := \frac 1{n-1} - x $$

REMARK:  Such functions $\ f_n\ $ don't exist for $\ n>2\ \ $
if   we want
     $\ f_n:\mathbb R_+\rightarrow\mathbb R_+.$

The uniqueness of each function $\ f_n\ $
(for $\ n>1)\ $ follows from its affine property:
$$ f_n(a)+f_n(d)\ =\ f_n(b)+f_n(c) $$
whenever $\ a\ b\ c\ d\,\in\,\mathbb R_+\ $ and
$$ a+d\ =\ b+c\ \le\ 1 $$
This is easy to prove (a good exercise), and it shows
that there is a constant $\ C_n\ $ such that
$ f_n(x) = C_n-x.\ $ Obviously, it must be
$\ C_n = \frac 1{n-1}.$

A final remark.   The case $\ n=1\ $ is different, there is no uniqueness due to its triviality. The decreasing condition is meaningless for $\ n=1.\ $ Thus different arguments are not glued together, they are totally independent. Hence no uniqueness.


text:
in: Inhabitants, Inhabitants of Toril, Inhabitants of Faerûn,
Inhabitants of Phlan
Warriors (2e)
Clerics
Clerics (2e)
Worshipers of Tyr
Clerics of Tyr
Inhabitants of the Moonsea
Inhabitants of North Faerûn
Basic Information[2]
Phlan, Moonsea[1]
Patron deity
1371 DR decapitated by barlguras
Rules Information
2nd Edition Statistics
Lawful good[1]
Warrior, Cleric[1]
Able was a warrior-cleric of Tyr who was a part of the rescue team sent to the Utter East to rescue Piergeiron the Paladinson's bride circa 1371 DR[note 1].[1]
"Able looked toward the docks with profound sadness in his eyes. "So many lost souls," he murmured to himself."[3]
Able was a close friend and an ally of Miltiades, Harloon, Trandon, and Kern Desanea of Phlan, where he was well known for his skill with a warhammer and clerical war magic.[1]
In the Year of the Unstrung Harp, 1371 DR, on Eleint 17 and 18, Able, along with other paladins of Phlan were in attendance at the wedding ceremony between the Open Lord of Waterdeep Piergeiron the Paladinson and Eidola of Neverwinter.[1]
The wedding was a disaster that resulted in the bride's abduction. Able was part of the rescue team assembled by Khelben Arunsun to travel through Undermountain to reach the only portal to the Utter East that was in the vicinity of the city. Blackstaff was unable to teleport the paladins to the portal directly because of Kern's anti-magical abilities, leaving the party with only one choice—traveling through Skullport.[1]
When the paladins reached Skullport, the group was tasked with aiding zombies by the mysterious Skulls of Skullport in penance for destroying one of the watchers. The group split apart in search of undead to aid. Able felt fear of the undead caused by his past failures to turn them with the power of Tyr; he sweated profusely, his breath was caught in short heaves and gasps. Even so, he had to perform the task. Able found himself in a city filled with the undead and, upon noticing a zombie that used to be a teenager, the cleric lost the last of his composure. He tried to destroy the walking corpse with his turn undead ability, and it failed. Instead, Able took his warhammer to the undead and disposed of the body. The cleric felt that he aided the zombie by releasing its spirit.[4]
After the paladins passed out of Skullport, they encountered a group of ettins. An unfortunate skirmish let to the death of Harloon, for whom Able delivered a prayer before the rescue team had to move on.[5]
Closer to the destination, the paladins came across tanar'ri aiming to use the same portal as the heroes. Barlguras were using a magical mirror located not far from the portal to create duplicates of themselves. Another battle broke out. Able felt the terror of not being able to access his god's divine powers to save his comrades. Thankfully, at the last moment, Tyr granted the cleric the power to stop the advancing tanar'ri. Able held them off long enough for the rest of the paladins to escape. A barlgura seized the cleric, ripping his head off but granting Able a heroic death in service of the god of justice.[6]
Able had iron-black hair and deep chocolate eyes. He kept his chiseled jaw clean-shaven even though it remained shadowed even with daily shaves.[1]
Able was a devoted follower of Tyr, but still had deep-seated insecurities and fears that interfered with his divine abilities. He felt shame and fear of the undead after one of his failed attempts to turn undead almost cost him his life. He was prone to panic facing the undead ever since.[4]
During Abel's heroic sacrifice, he was granted divine ability by his god. The symbol of Tyr on his warhammer burned bright, eliminating the entire cavern in holy light. He was able to hold a group of barlguras back, saving his comrades.[6]
Possessions[]
Able, like many other paladins and clerics, carried a holy symbol of his faith.[7]
He also wielded a warhammer adorned with Tyr's scales of justice on its head.[6]
↑ The Abduction, p.6 states that the wedding of Piergeiron the Paladinson and Eidola took place in the Year of the Haunting, 1377 DR. However, that date is implausible. Khelben Arunsun died in 1374 DR as depicted in Blackstaff (novel). Furthermore, Aleena Paladinstar was stated to be gone from Waterdeep by 1372 DR, planeswalking (City of Splendors: Waterdeep). On the other hand, the events of the Descent to Undermountain took place in 1370 DR, during which Aleena was actively banned from adventuring and any danger by her father. In the events of The Paladins, as well as the finale of the DDTS, Aleena took a central role, no longer bound by her father's rules. She later, with all the experience she received from battling the Unseen and hordes of Tanar'ri, felt confident enough to use her magic to traverse the planes. This places DDTS events likely in 1371 DR. This also does not conflict with appearances by Artemis Entreri, and the Neshers.
The Paladins
↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 James M. Ward and David Wise (February 1998). The Paladins. (Wizards of the Coast), p. 18. ISBN 0-7869-0865-3.
↑ James M. Ward and David Wise (February 1998). The Paladins. (Wizards of the Coast). ISBN 0-7869-0865-3.
↑ James M. Ward and David Wise (February 1998). The Paladins. (Wizards of the Coast), p. 36. ISBN 0-7869-0865-3.
↑ 4.0 4.1 James M. Ward and David Wise (February 1998). The Paladins. (Wizards of the Coast), p. 39. ISBN 0-7869-0865-3.
↑ 6.0 6.1 6.2 James M. Ward and David Wise (February 1998). The Paladins. (Wizards of the Coast), p. 67. ISBN 0-7869-0865-3.
Inhabitants of Toril
Inhabitants of Faerûn