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2012 Tommasi Poggio al Tufo Rompicollo
SOLD OUT! How often do you come across 93 point rated wines for less than $15? How about 93 point rated wines from one of Italy's most famous names in Amarone? Rarely, hardly ever, never!
Trust us folks, the 2012 Tommasi Poggio al Tufo Rompicollo is one of our best finds of the new year, and it's more than worthy of the press that has been bestowed up on it. After pouring it this past Saturday and running out way too fast, we think the wine loving folks who frequent Table Wine concur.
93 points Vinous Media
The famed Tommasi family of Valpolicella purchased the Poggio al Tufo Estate in 1997. Located in Maremma, along Tuscany's southwestern coast, this region has long been a hotbed of Super Tuscan activity. Ever heard of Tignanello, Sassicaia, or Ornellaia? These legendary estates were some of the pioneers of the region, and these days, their wines sell for hundreds of dollars.
What these famed estates and the Tommasi family recognized about the Maremma region were some very special traits that would allow them to propel Tuscan wines to new heights. First and foremost, it's all about the dirt, namely the vein of the famed galestro soil of Brunello di Montalcino that is prevalent throughout the region. This rocky, hard to work soil stresses the vines and yields wines with full, assertive flavors.
The region is also one of the warmest in all of Tuscany, and this allows for richer and riper Sangiovese as well as the cultivation of later ripening Bordeaux varietals (Cabernet Sauvignon and Merlot) and Syrah. When these grapes are combined in varying proportions, the net result is that you get complex red wines that combine the earthy, red fruit of Sangiovese with the darker fruit and more powerful structure of the other varietals. It's no surprise that the region has become known as Super Tuscan Central.
When the Tommasi family set up shop in the zone in 1997, one of their first creations was Rompicollo, a term that roughly translates as "neck-breaking" in English. The name was inspired by the backbreaking labor required to farm in the volcanic, Tufo-rich soils of the area. Trust us, there's nothing "hard" about buying or drinking this wine.
Rated 93 points by Ian D'Agata of Vinous Media (one of our favorite wine reviewing journals), that puts this one in the same ranks as wines that cost well north of $100. A blend of 60% Sangiovese and 40% Cabernet Sauvignon aged for 12 months in Slovenian oak, this one bursts out of the glass with ripe, warm aromas of cherry, blackberry, blueberry and plum along with more complex notes of sun baked earth, brown spice, and a touch of black pepper. On the palate, it's powerful but accessible, with well integrated tannins, plush fruit, and a 30+ second finish. Drink it with a big plate of Italian antipasto for simple pleasure or decant and drink with your favorite meat.
D'Agata said: "Dark bright red. Amarone-like opulence on the nose and in the mouth, with a raisiny nuance to the ripe, soft red cherry, sweet spice and herb aromas and flavors. So velvety and opulent I would have tasted it in Veneto had I tasted it blind, but it's so well balanced and smooth that it's pretty irresistible. Finishes long, with lush, smooth tannins and a hint of residual sweetness. I really like this wine because, for all its showy sweetness and opulence, it manages to retain a graceful quality without going over the top. Amarone lovers will score it even higher than I have."


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JC&A Promotes Trull to VP
Scott Trull
Quincy, MA – J. Calnan & Associates, Inc., a New England-based construction management firm, recently announced that Scott Trull has been promoted from project executive to vice president.
He successfully directed over 200 corporate office projects of all sizes, including work for high-profile companies and landlords such Parexel, Boston Properties, EMC, Pegasystems, Reebok, GE, SanDisk, Polycom, Philips, and Liberty Mutual to name a few. Throughout his nearly 20 years in the industry, he has also been able to work on projects for various universities on the East Coast and also has managed the construction of multifamily residential properties in Baltimore, Philadelphia, and New Jersey.
In his new role as vice president, Trull will focus on the continued advancement of JC&A's initiatives including the training and development of employees, technology tools, and overall processes and procedures.
Clients and fellow employees alike praise Mr. Trull for his commitment to each client and for his dedication to the successful outcome of every project. Mike Crowther, Chief Operating Officer said, "Scott is extremely passionate about his work and driven to achieve success. He has not only exemplified JC&A's approach to client development and delivering outstanding services, but has played a significant role in shaping the way we have adopted this as part of our culture."
A p316 people

redpajama_set_name: RedPajamaCommonCrawl


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Q: How to authenticate JIRA with deployd, angularjs and jira-connector? I am very new to JIRA and deployd.
I am having a problem with getting authentication from JIRA through deployd and angularjs.
I am using this npm service for JIRA connector
https://github.com/floralvikings/jira-connector
in my angularjs code here is the dpd post method
dpd.jira.post($scope.jira, function (result, err) {
        if (err) {
            return console.log(err);
        };
        console.log(result, result.id);
    });

In this $scope.jira, I am sending the host and base64 for authentication as mentioned in this doc
https://github.com/floralvikings/jira-connector#basic-authentication-base64
And in my dpd post event i am using this function
const JiraClient = require('jira-connector');
const jira = new JiraClient( {
  host: this.url,
    basic_auth: {
      base64: this.hashKey
    }
  });

Now I want to make sure if this authentication is valid or not,
If it is valid then the post will be a success else it will through error message.
How can I achieve this?
Thanks in advance
Please do not do any negative vote, as I am in serious trouble

redpajama_set_name: RedPajamaStackExchange


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Federated Wireless and Cambium Networks Enable Fixed Wireless Broadband Network Operators to Expand Coverage and Future-Proof Networks Over CBRS
Companies Team Up to Deliver Fixed Wireless Broadband Services Via CBRS ARLINGTON, Va. & ROLLING MEADOWS, Ill. – Federated Wireless, the leading shared spectrum technology provider, and Cambium Networks, a leading global provider of wireless networking solutions, today announced a partnership aimed at delivering Citizens Broadband Radio Service (CBRS) connectivity to Cambium Networks' Fixed Wireless...
Syniverse, Ruckus and Federated Wireless Enable Private LTE Networks Leveraging Shared CBRS Spectrum for Enterprises
Private LTE network launched at Syniverse Innovation Lab opens a new era in high-quality, high-security mobility
Packet Announces Edge Access Program to Accelerate Use Cases
Open source, industry and commercial partners to take advantage of edge computing building blocks
Casa Systems to Introduce CBRS Portfolio at 2019 MWC Barcelona
Casa's end-to-end CBRS solution opens up new opportunities for U.S. service providers while addressing the need for additional network capacity and bandwidth
Federated Wireless and Packet Announce "Wireless Test Kitchen" to Accelerate Developer Innovation in Private LTE
Joint platform integration to enable a fully API-driven solution for wireless connectivity Arlington, Va. and New York – February 21, 2019 — Taking the next step towards a developer-led model for wireless infrastructure, Federated Wireless and Packet today announced a joint "Wireless Test Kitchen" in Boston, MA that allows developers and Enterprises to programmatically build...
Federated Wireless Leading the Wave with First Round of CBRS Customer Deployments
Company's CBRS Deployment Momentum Signals Accelerated Industry Adoption, Fueled by Wide Range of Band 48 Devices Now Available Arlington, Va. – February 21, 2019 – Federated Wireless today announced the submission of a supplement to its Initial Commercial Deployment (ICD) application to the Federal Communications Commission (FCC), expanding it to include planned deployments from 25...
Taking Shared Spectrum To The Edge With The Kinetic Edge Alliance
Following several collaborative discussions with leaders in edge computing, it brings us great pleasure to announce our participation in the launch of the Kinetic Edge Alliance (KEA). The KEA is an industry alliance of the top software, hardware and networking companies committed to driving the broad adoption of compute, storage, and access at the edge...
Federated Wireless Expands Leadership in National Spectrum Consortium
Federated Wireless recently expanded our leadership role in spectrum sharing when I was honored to be elected Chairman of the National Spectrum Consortium. The National Spectrum Consortium incubates new technologies to revolutionize the way in which spectrum is utilized. Through collaboration between our over 200 industry partners and Government agencies, the NSC solves the toughest...
Federated Wireless Announces Appointment of Steven Marshall as Senior Advisor
Top Wireless Industry Executive to Work Alongside Federated Wireless Leadership as Company Commercializes CBRS in U.S. and Eyes Global Adoption of Shared Spectrum Model Arlington, Va. — February 5, 2019 – Federated Wireless, the leading shared spectrum technology provider, today announced the appointment of Steven Marshall as senior advisor to company leadership. In this...
Utility Industry Leaders Join New Alliance to Champion Private Broadband Networks for Critical Infrastructure
Utility Broadband Alliance (UBBA) to become hub of information sharing, collaboration and planning to advance dedicated wireless connectivity for an increasingly interconnected and distributed grid
Comments On Developing A Sustainable Spectrum Strategy
The Federated Wireless team continues to lead the shared spectrum wave, and, in doing so, sets up the United States to lead the 5G wave. This was an initiative President Trump outlined late last year, and we gladly accepted the challenge. Preparing For The Future of 5G We recently filed a document in response to...
How Can Enterprises And Venue Owners Benefit From CBRS?
If you run an enterprise organization or venue and struggle to provide good cellular coverage to your users, it's time to consider the many benefits of CBRS. We are diligently in the thick of planning Initial Commercial Deployments and what better time to revisit the impact of CBRS on a variety of industries that rely...
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#009: The 5 Root Causes of ALL Autoimmune Disease – LIVE with Brett Hawes
https://chtbl.com/track/745447/www.holistic-health-masterclass.com/podcast-player/3438/root-causes-autoimmune-disease-live-brett-hawes.mp3
Download file | Play in new window | Duration: 01:43:19 | Recorded on February 6, 2018
Today's show was recorded LIVE at an event near the end of 2017. We dive deep into the 5 root causes of autoimmune disease and discuss strategies to support those with AI disease.
I get into a number of areas including leaky gut, food allergies and intolerances and GMO's. I discuss the role of stress and the 'perfect storm' scenario as a major catalyst for AI disease. Lastly, I cover some more obscure topics like stealth infections and viral triggers.
There is a Q & A toward the end that covers some unrelated topics but still worth the listen.
You can find additional resources on the following blog posts here, here
Listen to the show directly on our Holistic Health Masterclass Podcast page. You can also subscribe and listen via your favourite podcast app listed below.
iTunes: https://apple.co/2ytDi8K
Google Play: http://bit.ly/2ksWSNg
Stitcher: http://bit.ly/2CIImZT
ADRENAL DYSFUNCTION MASTERCLASS
#125: Chlorine Dioxide, MMS and Autism January 19, 2023
#124: Future Pandemics and the WHO January 11, 2023
#123: 2023: The Vision Forward January 11, 2023
#122: Home Testing for Better Health w Vivoo August 4, 2022
#121: Brain Retraining for Chronic Health Issues w Ashok Gupta July 20, 2022
Please Rate and Review the Podcast
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Brett is a treasure-trove of sound nutritional knowledge and always tackles complex issues with great understanding. He also brings a genuine spirit of wanting to help people solve their health problems and find a way to live in balance. I always enjoy speaking with him and listening to his take on the chronic health issues of today.
Dr Ginger Nash - Women's Health Expert & Founder of Feminology
I've had the pleasure of knowing Brett as an instructor at the Institute of Holistic Nutrition and as a colleague since. He is exceptionally knowledgeable in the field of holistic health as an instructor and practitioner and presents information and concepts in an engaging way to his students.
Rachelle Wintzen -Founder and Clinic Director at Chi Junky Studio
Brett's teaching ability is very enlightening and thought provoking, not just directive. I found his background, travel experiences and extensive client work to be highly valuable to my own development. Brett has a way of connecting with the students in a very down to earth manor, allowing us to open up, while still maintaining his authority and ability to stay on task. His passion for what he does shines through in all his teachings and he presents a real genuine desire for his students to succeed.
Sara Fennell - Nutritionist. Pro Athlete and Host of the "Fulfillment Project Podcast"


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For the past 15 years, I have developed courses in MICE management and taught that subject in a number of universities in the UK and overseas
Specialist MICE education programmes in universities worldwide are growing steadily, as educators are beginning to understand the importance of our industry as a source of exciting and gainful careers for their students.
My principal employers were two outstanding London universities, and I would highly recommend them to anyone who want to study – or teach – subjects relevant to the MICE industry. At the University of Greenwich, with my colleague Nick Wilde, I developed an undergraduate course in Events Venue Management. And at the University of Westminster, I developed a Masters course in Events and Conference Management.
University of Greenwich MA in Events Management and BA in Events Management
University of Westminster MA in Events and Conference Management and BA Tourism and Events Management.
I continue to work as a Visiting Professor, teaching MICE management on a regular basis in these universities. This gives me the opportunity to inspire and educate the next generation of MICE professionals, and that is a both a pleasure and a privilege for me.
SKEMA, Sophia Antipolis, France Strategic Event Management and Tourism Management
Università della Svizzera italiana, Lugano, Switzerland Master in International Tourism
University of Applied Sciences, Kufstein, Austria Masters in Sports, Culture & Event Management
Ecole de Management, Strasbourg, France Master Marketing et Gestion d'Evènements
Courses creator
Visiting Professor
From Our Portfolio
Better Business Results Through Motivational Experiences and Incentive Travel
Winning Meetings and Events for your Venue
EIBTM 2013 Trends Watch Report


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Lacing up to skate at 88: Hockey-loving B.C. man inspires teammates
Jay Durant GlobalNews.ca
He's 88-years-old and still delivers a mean check on the ice. Abbotsford's Henry Unger has been playing hockey most of his life and is inspiring much younger members of his team. Jay Durant has more on This is BC.
It's game day in Abbotsford, B.C., and Henry Unger is gearing up for his third game this week.
"Let's play hockey," shouts the 88-year-old from the dressing room hallway as the team waits for the Zamboni to clear the ice.
'I wanted to be famous': Abbotsford, B.C. man holds world records for ball-spinning
Unger is doing his part to get everybody on his 55-and-over team fired up.
"Is he an inspiration to you younger guys?" teammate Don Tuck was asked. "Ha, I thought I was old when I came here now I'm a young guy now."
Unger says he put on his first pair of skates all the way back in 1939.
"As I remember they cost $3.75," Unger told Global News.
He remembers he would use magazines for shin guards. He loves to share stories of a simpler time for the sport.
"He says 'when I started playing hockey it was with homemade sticks and frozen horse crap,'" team goalie Mark Wilkinson said.
"We're having fun, and we're getting exercise," Unger explained from the bench between shifts.
B.C. group needs thousands of dollars to get donated baseball gear to kids in Mexico
Most people don't try to make a comeback at age 88.
He actually had to teach himself how to skate again, after taking the last year-and-a-half off.
"I literally had to hold onto the boards so I could turn around and skate backwards," he said, after finally getting back onto the ice.
Unger is quite a bit older than most of the players, but out on the ice, he's just one of the guys.
"When he goes onto the ice, he takes his hearing aids out so we can trash talk him all day long and he just smiles at us," joked teammate Gary Gogal.
While he might be an old-timer, Unger still has plenty of skills.
"He may not be blazing up and down, but you do not want to take him for granted, he plays good hockey," said longtime friend Tom McBratney.
"He checks you pretty hard, he doesn't give you an inch," warned teammate Bill Stroomer.
Metro Vancouver artist turns trash into treasure by using plastic to create stunning art
Once in a while, the seas will part and the ice opens up giving Henry a chance for a goal.
"I have to admit that on occasion they give me a little of extra room," he said.
So how many goals did the 88-year-old manage to slip past the goalie on this particular outing?
"One, but I got three assists," he said, admitting his stats wouldn't earn him the league MVP title.
If you were to ask the other players, though, about who would win as the most inspirational player? "Henry!!" his teammates call out, while posing for a picture at centre ice.
Of course, it's Unger who is right in the middle.
To contact Jay Durant with a story idea for This is BC, email him details and contact information at thisisbc@globalnews.ca


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Oprah Winfrey One Of World's 500 Richest People
Ria Das
Oprah Winfrey has become the first Black female entrepreneur on the Bloomberg Billionaires Index. With a record $4 billion fortune, she ranks as one of the world's 500 richest people at 494. The Queen of all media is ranked just behind Mark Cuban and Ross Perot.
One of the many reasons to increase Winfrey's fortune this year was the performance of Weight Watchers International Inc. The firm led Winfrey's fortune to hit a whopping $427 million so far this year as the company's share price has more than doubled. The famous producer and philanthropist started the weight-loss firm which has had a celebratory comeback since 2015.
ALSO READ: 10 Quotes On Failure That Will Lift You Up
The Academy Award nominee has earlier this year won the Golden Globes Cecil B. DeMille award for lifetime achievement. She is the first Black woman to win the award
The Oprah Winfrey Show, running for 25 years now, has gone on to become the highest-rated television program of its kind in history.
Partnership deal with Apple Inc
The founder of her own cable network, Winfrey just signed a deal in partnership with Apple Inc. to produce original programs and content. The company is looking forward to competing with brands like Netflix, Amazon and Hulu.
Winfrey will continue to head the channel, OWN as the CEO. Winfrey is ranked one of the richest the richest African-American, the greatest Black philanthropist in American history, and is currently North America's first and only multi-billionaire Black person.
Read Also: Apple Plans To Launch Disabled-Friendly Emoji
Also Read: The Story of Oprah Winfrey in 14 Milestones
Picture By: Daily Mail
african americanfemale entrepreneurHollywoodOprah WinfreyThe oprah winfrey showWeight Watchers Internationalworld's 500 richest people


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David Kilgour And The Heavy 8s / End Times Undone
Album: End Times Undone Collection: General
Artist: David Kilgour And The Heavy 8s Added: Oct 2014
Label: Merge Records
Add Date: 2014-10-31 Pull Date: 2015-01-02
Week Ending: Jan 4 Dec 28 Dec 14 Dec 7 Nov 30 Nov 23 Nov 16 Nov 9
Airplays: 2 1 2 1 3 2 3 3
1. Jan 02, 2015: Time Traveler
Comin' On 4. Dec 12, 2014: Time Traveler
Comin' On
2. Dec 29, 2014: In The Year One Thousand, Eight Thousand: Best of The Year 2014. Part 2!
Lose Myself In Sound 5. Dec 11, 2014: Meow
Like Rain
3. Dec 26, 2014: Time Traveler
I Don't Want To Live Alone 6. Dec 05, 2014: Time Traveler
Upbeat indie pop with an early 2000s sound, with some surprises along the way. David Kilgour of New Zealand, former frontman of indie group The Clean, has come out with an album that is at once laid-back and playful, mature yet carefree. Catchy throughout and gets better with more listens, though some songs still blend together too easily.
Favorites: 5, 8, 9. No FCCs noted though "hell" is prominent on track 4.
1. (4:12) Sleepy, psychedelic fade-in. Slow to mid-tempo. Titled "Like Rain," but "Like a Light Drizzle" would fit even better. Picture the opening credits of a charmingly dysfunctional family film (looking at you Little Miss Sunshine).
2. (3:35) Opens with a bright electric riff. Melodic, simple but uplifting. Pleasant grungy noise scattered throughout.
3. (3:02) Slowed down, mostly instrumental, rolling toms and piano. Theremin-like psychedelic sounds and whispered vocals come in around :50. As if Yo La Tengo and Wilco had a pretty chill baby.
4. (3:21) Mid-tempo, country-inspired. More spring cheer in the strumming. Exploratory in both sound and theme: "Christopher Columbus knew/yeah, he knew/what the hell you're gonna do?.... Everybody needs a rest." Note for the repeated usage of the word "hell."
5. *(2:32) A meandering, more mysterious guitar piece and lower, darker vocals to accompany the change in mood. There's a background "twang" that grabs you and keeps going. Very Yo La Tengo again, hints of Interpol?; my favorite track.
6. (3:18) Return to Cheery Mountain, for the most part. Echoes hypnotize until power chords cut through the haze. Elements of Supergrass or Oasis.
7. (4:45) "Wrestling with the same old highway." Similar feeling to #4. Sonically, highs and lows and highs again. Mid-tempo.
8. *(3:10) A refreshing break. Unadorned keys that sound optimistic on their own but lead to the stark, suddenly clear, lonely vocals. "I don't wanna live alone/it takes too long."
9. *(4:34) Gradual, plucking build up to a lush full-band mid-tempo track. Around 2:30 becomes louder and more urgent, with scratchier guitars and angrier drums until it comes to a close.
10. (2:50) Resonates well with track 1. Upbeat, short and sweet, despite bitter lyrics about the failures of communication. Jangly guitars driving to an end.
1. Like Rain 6. Dropper
2. Lose Myself In Sound 7. Comin' On
3. Light Headed 8. I Don't Want To Live Alone
4. Christopher Columbus 9. Down The Tubes
5. Crow 10. Somethings You Don't Get Back


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PM Maliki's bloc biggest winner in Iraq election
Iraqi Prime Minister Nuri al-Maliki casting his vote in Iraq's first parliamentary election since US troops withdrew at a polling station in Baghdad's fortified Green Zone. (AFP)
Maliki's State of Law parliamentary bloc wins 92 seats in the 328-member parliament but falls short of a majority
Prime Minister Nouri al-Maliki's political coalition has emerged as the biggest winner in Iraq's general elections, according to preliminary results announced Monday.
Maliki's State of Law bloc won 92 seats in the 328-member parliament, said the Independent High Electoral Commission. It took the lead in 10 of 18 provinces.
The runners-up were his two main Shiite rivals: cleric Ammar al-Hakim's Al-Muwatin bloc with 29 seats, and cleric Muqtada al-Sadr's Al-Ahrar bloc with 28 seats.
The elections, held in late April, were the third since the 2003 U.S.-led invasion of Iraq that led to the removal of Saddam Hussein's Sunni-led regime and brought the Shiite majority to power.
Although the results boost Maliki's chances for a third term, the Shiite politician needs to secure a broader majority coalition that will get the first chance at forming a government.
Maliki will likely need the support of Sunni Arab and Kurdish parties to succeed.
However, many of them have refused to countenance another term for Maliki, who they accuse of consolidating power and causing a protracted surge in unrest.
Regardless of the final results, the cabinet formation process is expected to take months as the various parties are likely to seek an all-encompassing government package, including the selection of the president and the speaker of parliament.
Under a deal between Iraq's communities, the prime minister is a Shiite Arab, the president a Kurd, and the parliament speaker a Sunni Arab.
The election and its aftermath come amid a year-long surge in violence that has left more than 3,500 people dead this year.
This is fuelling fears that Iraq could slip back into the all-out conflict that left tens of thousands dead in 2006 and 2007.
The election tallies were delayed for weeks due to a litany of complaints, the election commission said. The results are subject to challenge.
[With AFP and Reuters]
nouri al maliki
iraq elections
Iraq election candidate kidnapped in Baghdad
Rahman Abdulzahra al-Jazairi was near his home in the predominantly Shiite neighbourhood of Jamila Middle East
Thousands flee Iraq government assault on rebel-held Falluja
Thousands of civilians have fled Falluja since last week after the Iraqi military intensified shelling in a new bid to crush a five-month old Sunni ... Middle East
ICC prosecutor to examine alleged British crimes in Iraq war
The Hague-based court had previously concluded an examination of similar accusations in 2006 World News
Series of attacks in Iraq kill nine people
More than 3,200 people have already been killed this year News
Militants kidnap, kill 20 Iraqi soldiers
The soldiers were kidnapped by militants in north Iraq, who later shot them dead Middle East
Inside al-Qaeda in Iraq
Death Making
Thousands flee jihadist clashes in Syria
Clashes between al-Nusra Front and the rival Islamic State of Iraq and Syria (ISIS) have killed 230 militants in the last 10 days Middle East


What is Kid Cudi net worth?
Talking about his childhood, Kid Cudi was born in January 1984, as Scott Ramon Seguro Mescudi. He spent most of the childhood in Shaker Heights. He is the youngest of all siblings and has two elder brothers named as Domingo and Dean. He has an elder sister named as Maisha. Kid Cudi was born to engineers, Elsie Harriet and Lindberg Styles Mescudi. He said he feels sorry about the incident when his mother passed away due to cancer. He was only of 11 when he lost his father due to a severe illness. He studied at the University of Toledo, but could not continue his studies. Still, he has managed to earn a lot.


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10th Annual Music Unites the World Festival Premieres Online – May 22 & 23
Contact: Katie Boone
Email: press@etmla.org
Website: www.etmla.org
LOS ANGELES, CA – This past March, after months of preparation, the game plan was finally set to go into motion for Education Through Music-Los Angeles's 10th Annual Music Unites the World Festival. Students spent weeks — countless hours — diligently rehearsing their songs for the special moment when they would come together with their peers from across LA County. They were brimming with excitement for March 11th and 12th!
ETM-LA staff had begun load-in at Cal State LA, the 2020 festival venue, when word arrived that all outside events taking place on campus were immediately cancelled for the foreseeable future. Everyone involved was heartbroken, and ETM-LA was devastated to have to tell over 1,000 students and parents that the festival was called off.
The annual festival is a tradition that celebrates the joy of making music together and the ability of music to unite any and every one. Students from ETM-LA partner schools across Los Angeles County come together for two days of community building, music making, and training from professional educators, musicians, and celebrities. This is a truly unique experience for the children involved, who would otherwise not have such an opportunity.
Despite the cancellation, ETM-LA's drive to hold this festival has never wavered. Maya from Rio Vista Elementary observes, "In trying times, supporting one another and attempting to understand one another is vital to moving forward. Music is one of the most simple and beautiful ways to do this." Now, as everyone has settled into the new normal and virtual connection has become the answer during this time of Safer at Home, the solution is obvious. The virtual show must go on!
Education Through Music-Los Angeles is premiering its 10th Annual Music Unites the World Festival on Facebook Live and YouTube on Friday, May 22nd at 5pm PST (with an encore showing on Saturday, May 23rd at 2pm PST). Hosted by Actor/Musician Ricardo Hurtado (Malibu Rescue) and Singer/Actress Bridget Barrera (Wizards of Waverly Place), this year's virtual festival will include student performances, award-winning essays, interactive music activities — including a percussion class from Arthur Thompson (Dave Koz) and a sing-along! — and the first-ever ETM-LA virtual choir performance.
Tune in on Facebook and YouTube!


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Reporters & Officers
Oath & Ethical Code
Advertisements & Donations
Scoops & Submissions
The Tiger Times
A public forum for students of The Fleetwood Area School District
Draper's Descent Headlines Mad Men Season Seven
Posted on June 6, 2014 by thetigertimes
Mad Men is an American television drama that debuted on AMC in 2007 and is now in its seventh and final season. The season was broken up in two halves, with the first half wrapping up last Sunday and the second half to air next year. AMC used this same model with Breaking Bad and was successful in drawing in new viewers as well as keeping the attention of old ones.
Mad Men has been lauded by critics for being a realistic look at the world of advertising in the 1960s. The show's main character, Don Draper (Jon Hamm), is an enigmatic creative executive with a shady past and who struggles with what some would call alcoholism. The start of season seven saw Draper ostracized by his advertising firm after breaking down emotionally in a meeting.
He returns in season seven only to find himself in a demoted position and with new restrictions. The show's writers have hinted at, both overtly and subtlety, the fact that Draper is losing his importance in the office. In the most obvious metaphor for his diminished worth, a room-sized computer is installed where the creative team used to work. The computer represents the future for both advertising and America in general.
Other characters are struggling to adapt to the changing atmosphere in America during this time (the year is now 1969). Peggy Olson (Elizabeth Moss), who has been slowly rising through the ranks of the advertising firm since her arrival as a secretary in season one, found herself in a position of newly-acquired power at the beginning of season seven, but the stress of the job seems to be taking a toll on her. She already broke down earlier in the season, and who knows where she'll be at the end of the season next year?
Peggy is unique in that she is one of the few females with a high ranking job in this time period, and perhaps this is why she feels extra pressure to succeed. Watching her rise to the position has been one of the more interesting storylines in the series.
Of course, there are many other characters and subplots that cannot be discussed because of spoilers. If you have the time, the series is available on Netflix instant view for streaming up to the most recent season. It is well worth the ride, and there's plenty of time to catch up before the show wraps up next year.
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The Tiger Times is a high school news journal that is produced using funds from The Fleetwood Area School District as well as club fundraisers. All subjects and topics appearing within The Tiger Times are self-selected by student reporters themselves; however, article suggestions are accepted from all students, staff, administration, and community members. Opinions and viewpoints stated in The Tiger Times are not necessarily the opinions and viewpoints of the Fleetwood Area School District, its administration, its faculty, the club advisor, or even the entirety of The Tiger Times staff. The Tiger Times is a public forum whose primary goal is to provide an outlet for student expression to The Fleetwood Area School District and its constituent communities. Viewpoints and opinions that are contrary to those appearing in The Tiger Times are welcomed, but they are not guaranteed publication except by approval from the student editors. Students who are not matriculated in the Journalism course or who are not among the club's roster are still eligible to submit content for the periodical. All articles and letters selected for publication may be subject to editing for length and language consistent with the style established by student editors of The Tiger Times.


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U.S. economy is back to normal, says Fed's Williams
Kelvin Ching Updated on March 30, 2017
Congratulations, America. The economy is finally back to normal.
That's what John Williams, the head of the Federal Reserve Bank of San Francisco, declared Wednesday.
"The data have spoken, and the message is clear: We've largely attained the hard-sought recovery we've been after for the past nine years," Williams told the Forecasters Club, a gathering of economists, in New York. He dubbed it a "Goldilocks economy."
Unemployment peaked at 10% after the Great Recession. Today it's just 4.7%, a level Williams said constitutes "full employment" because there will always be some job seekers, even in a healthy economy. Inflation is also "nearing" the Fed's goal of 2%, he said.
The Fed raised interest rates this month for only the third time since the financial crisis. The central bank is expected to raise rates two more times this year, but Williams hinted again that three more hikes might be appropriate in 2017.
He said Wednesday that the Fed is as close "as we've ever been" to achieving its goals of full employment and stable inflation.
Williams argued that it's time for the Fed — and Washington — to shift from obsessing about "How do we achieve a sustained recovery?" and focus on "How do we sustain the recovery we've achieved?"
But Williams does think the U.S. economy needs faster growth. The economy has struggled to expand much faster than 2% a year in this recovery. Last year, the economy only expanded 1.6%.
President Trump has said he can deliver 4% growth. Treasury Secretary Steven Mnuchin has indicated that at least 3% is achievable.
Post Tags: #Federal Reserve Bank#financial#Forecasters Club#Great Recession#growth#John Williams#NEW YORK#President Trump#recovery#San Francisco
U.S. jobless claims slip less than expected for week ending March 25
Global stocks edge up on higher oil prices, U.S. GDP revision
CNY News
China GDP expected at 7.6% for second half of 2013, but risks are growing
ByHenry Liu July 4, 2013 July 4, 2013
CAD News EUR News USD News
Major oil producing countries selling stocks to pay bills
ByKelvin Ching February 23, 2016
US trade deficit shrinks to lowest level since October 2009
ByHenry Liu August 7, 2013 August 7, 2013
GBP News
UK economic outlook slumps on eurozone crisis
ByHenry Liu July 31, 2012 August 1, 2012
It's finally here; Fed to hike interest rates for first time since June 2006
ByKelvin Ching December 11, 2015
Was Boehner's 'Plan B' to avert 'fiscal cliff' a disaster?
ByHenry Liu December 22, 2012 December 26, 2012


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Every single Michael B. Jordan movie, ranked by critics
"Creed," "Just Mercy," and "Black Panther" are three of Michael B. Jordan's highest rated movies.
Metro-Goldwyn-Mayer/Warner Bros. Pictures/Warner Bros. Pictures/Walt Disney Studios Motion Pictures
As well as being named People's Sexiest Man Alive for 2020, Michael B. Jordan is one of the most talented young actors and producers working in Hollywood.
Jordan has recently transitioned into an executive producer as well as a star, producing movies such as "Just Mercy" and "Creed II."
Both of those movies feature highly in this list of Jordan's best movies ranked by their Rotten Tomatoes scores.
"Fantastic Four" is his lowest rated movie with 9%, while "Black Panther" is second-highest with 97% and a surprising DC movie is top with 100%.
Jordan played the Human Torch in the 2015 'Fantastic Four' reboot
"Fantastic Four" was directed by Josh Trank.
Michael B. Jordan is one of two actors to have played the Human Torch and also appear in the MCU, along with Chris Evans. Jordan played this incarnation of Johnny Storm in this critically-savaged reboot from Josh Trank.
Thankfully, Jordan's transition to the MCU proved much more successful.
In 2014, Jordan appeared as Mikey in 'That Awkward Moment'
"That Awkward Moment" was directed by Tom Gormican.
Jordan starred in this 2014 movie with his future "Fantastic Four" costar Miles Teller, with Zac Efron also along for the ride. The movie follows three friends who get caught in the moment where a relationship potentially turns more serious: when one partner asks the other where it's going.
Jordan played Guy Montag in the 2018 adaptation of 'Fahrenheit 451'
"Fahrenheit 451" was directed by Ramin Bahrani.
Based on the classic novel by Ray Bradbury, Jordan takes the starring role as a firefighter tasked with burning books who eventually begins to rebel against society after meeting a young woman. Michael Shannon also stars.
JIn 2018, Jordan was credited as Male Cleaner in the James Franco-starring sci-fi 'Kin'
"Kin" was directed by Jonathan Baker and Josh Baker.
Jordan has a small but important role in this movie as a character credited as the Male Cleaner. This sci-fi movie follows a young boy who stumbles upon a strange weapon, leading to a variety of sci-fi troubles. Zoë Kravitz, Carrie Coon, Dennis Quaid, and James Franco all star.
In 2012, Jordan played Maurice in the WWII drama 'Red Tails'
"Red Tails" was directed by Anthony Hemingway.
Jordan joined Leslie Odom Jr, Ne Yo, David Oyelowo, Nate Parker, and Cuba Gooding Jr. to play a group of African-American pilots during WWII who are called into action by Terrence Howard's ' Col. A.J. Bullard.
A very young Michael B. Jordan appeared in 2001's 'Hardball,' starring Keanu Reeves
"Hardball" was directed by Brian Robbins.
A 14-year-old Jordan appeared in this comedy baseball movie starring Keanu Reeves. Reeves is a troubled gambler who is forced to pay off his debts by coaching a kids baseball team for 10 weeks.
Jordan produced and starred in 'Creed II' as Adonis Creed in the 2018 sequel
"Creed 2" was directed by Steven Caple Jr.
Metro-Goldwyn-Mayer/Warner Bros. Pictures
In the sequel to the hit 2015 "Rocky" reboot "Creed," Jordan reprised his role as Adonis Creed, this time preparing for a fight with Viktor Drago, the son of legendary Rocky rival Ivan. Fellow MCU alumni Tessa Thompson also stars in the movie, as Adonis' girlfriend.
In 2019, Jordan played real-life lawyer Bryan Stevenson in 'Just Mercy' alongside Jamie Foxx
"Just Mercy" was directed Destin Daniel Cretton.
In one of Jordan's heavier roles, Jordan plays a real-life superhero: American lawyer and social justice activist Bryan Stevenson. In the movie, Stevenson tries to help out a wrongly-convicted man, played by Jamie Foxx, who is on death row.
In 2012, Jordan played high-school superhero Steve Montgomery in 'Chronicle'
"Chronicle" was directed by Josh Trank.
Jordan first worked with "Fantastic Four" director Josh Trank on this indie superhero movie where three high-school pals gain special powers but start to embrace their dark sides as a result.
In 2013, Jordan played Oscar in Ryan Coogler's 'Fruitvale Station'
"Fruitvale Station" was directed by Ryan Coogler.
Jordan formed another important relationship with an eventual tent-pole director in a small indie drama. This time, Jordan starred in Ryan Coogler's "Fruitvale Station" which follows Oscar Grant III, who was killed in 2009 by a BART police officer on the last day of his life. Jordan and Coogler would later reunite for "Creed" and "Black Panther."
Jordan starred as Adonis Creed for the first time in 2015 alongside an Oscar-nominated Sylvester Stallone in 'Creed'
"Creed" was directed by Ryan Coogler.
Reuniting with Coogler, Jordan starred in the "Rocky" reboot for the first time in 2015, playing Adonis Creed, son of Apollo Creed who was a rival-turned-friend to Rocky earlier in the franchise.
Sylvester Stallone returned as Rocky himself, taking on an older, Obi-Wan Kenobi-like mentor role to Jordan's young challenger. Stallone even earned himself an Oscar nomination for best supporting actor.
Jordan reunited with Coogler again to play the villain, Erik Killmonger, in 'Black Panther' opposite Chadwick Boseman
"Black Panther" was directed by Ryan Coogler.
Second in this list is Jordan's triumphant arrival to the MCU. Jordan plays Erik Killmonger, the cousin of Chadwick Boseman's T'Challa (AKA the Black Panther). Killmonger plots a return to Wakanda in an attempt to overthrow the king. Killmonger is one of the MCU's best-ever villains.
The character of Killmonger, his motivations, and Jordan's swaggering performance were all so complimented that he is rumored to be making a return to the sequel despite dying in the first movie.
Jordan voiced Cyborg in DC's 2013 straight-to-video movie 'Justice League: The Flashpoint Paradox'
"Justice League: The Flashpoint Paradox" was directed by Jay Oliva.
Surprisingly, Jordan's highest-rated movie on Rotten Tomatoes is not his much-loved performance in the MCU's "Black Panther," but this appearance in an animated DC film.
Jordan voices Victor Stone, AKA Cyborg, in this straight-to-video movie, which follows the Flash stuck in an alternate timeline and having to work with alternate versions of heroes and friends to get back to his own timeline.
More: Features Michael B. Jordan Creed MCU


Unknown to Wallace Findings, a one-night stand results in twins. The mother is murdered soon after their birth to cover a hideous crime, which sends Findings on an eighteen year hunt for her murderer. One twin is adopted and welcomed into a wonderful life of plenty and privilege. The other is rejected and left an orphan, in a world without identity or care, facing brutal treatment and sexual abuse. This twin seeks out Findings and his sibling and all those who had abandoned him to carry out a plot of revenge. In the end, Findings discovers his role in a baby for sale scheme in which he and his unknown children were victims.


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Tibetan Buddhist monks create artistic symbol of enlightenment - here today, gone on Sunday
By Janette Williams, Pasadena Star News, Nov 4, 2010
PASADENA, CA (USA) -- For five days, five Tibetan Buddhist monks will hunch over a table, holding their breath as they place grains of brilliantly dyed river sand to create a sacred mandala.
<< Venerable Thupten Nima, left, Venerable Lobsang Dhonyoe, Venerable Longsang Tsetan drawing of the lines in Mandala painting at Pacific Asia Museum in Pasadena Thursday, November 4, 2010. Five visiting monks from the Drepung Loseling Phukhank Khangtsen Monastery in southern India are at the Pacific Asia Museum to create a sand mandala, and will complete it by 1 p.m. Sunday and at 2 p.m the mandala will be swept away.(SGVN/Staff Photo by Walt Mancini)
At 1 p.m. Sunday at the Pacific Asia Museum, 46 N. Los Robles Ave., they will put the last hand-ground grain in the mandala's intricate pattern symbolizing compassion, enlightenment and the world in its divine form.
At 2 p.m. they will destroy it.
"That's the message in it," said Lobsang Dhonyoe, a 32-year-old monk from the Drepung Loseling Phukhang Khangsteen Monastery in Southern India. "Nothing is forever."
Speaking through translator Tenzin Sherab, Dhonyoe said the monks never have the feeling they want to make their painstaking work permanent.
"It's like flowers, or people," he said. "One day, everything will die."
The monks, who are on a three-and-a-half month tour of the Western U.S., are from a monastery founded 500 years ago in Lhasa, Tibet, then re-established in Mundgod, India, in 1976 with help from the Dalai Lama.
Sherab said visitors are welcome to watch the monks work from 10:30 a.m. to 3:30 p.m. daily, free of charge, and return to watch the mandala progress.
On Sunday, at the "Dissolution Ceremony," the mandala will be blessed a final time and swept into a pile. According to tradition, some of the sand will be given to visitors as a blessing for their homes or gardens and the rest will be returned to the ocean.
The monks never get nervous having an audience watch the painstaking process, Dhonyoe said, and their meditation skills allow them to control their breathing and concentrate for long periods.
"Sneezing is far away," Sherab joked.
With forearms and wrists steadied on small cushions, the monks' lean inches away from the fine sand they are placing and layering on the outlined map. The sand flow from the narrow tapering end of a long metal scoop is controlled with taps from a metal rod, and no one is breathing as the elaborate pattern takes shape.
Katherine Murray-Morse, the Pacific Asia's interim executive director, said this is the first visit by monks from this monastery, famed for its monks' skill in the Tibetan Buddhist art of sand mandala.
Olivia Garfield of Pasadena, with her mother - also Olivia Garfield - visiting from New Hampshire, were fascinated by the mandala's progress Thursday.
"They just spend so much time doing it - and then, oh, just throw it away?" the elder Garfield said.
A mandala is so colorful and precise that it can look a little unreal - as the monks found out in their recent visit to San Jose.
"We were having lunch, and we'd put barriers around" the mandala, Sherab said. "One lady was watching the mandala. We thought it was fine, and all of a sudden she pushed her finger over it. Luckily it was the first day."
The monks "just laughed," Sherab said, "but I yelled at her...she said she was sorry."
For more information, call 626-449-2742, ext. 23.
Read more: http://www.pasadenastarnews.com/news/ci_16526391#ixzz14Qq67vDa


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Home Page / Home / Business / On This Day In Comedy… In 1902 Mantan Moreland Was Born!
On This Day In Comedy… In 1902 Mantan Moreland Was Born!
By Humor Mill / September 3, 2015 / Business
On this day in comedy in 1902 comedian, Actor, Mantan Moreland was born in Monroe, Louisiana
The adolescent runaway joined a minstrel show in 1910. By 1920 Moreland was a veteran performer of vaudeville, Broadway and had toured Europe. His film debut took place in a "race film" (which he did many), but it wasn't long before Hollywood beckoned and he was signed to Monogram Pictures and a co-starring contract to play in action pictures opposite Frankie Darro then transitioned into the role of detective Charlie Chan's chauffer, Birmingham Brown.
In a career that included appearances in over 300 films, Moreland chiefly appeared as shoe shine boys, waiters and porters. Mantan's physical trembling and eye bulging whenever danger was about earned him a reputation as a premier big screen funnyman. He also worked the Apollo Theater with partner, Ben Carter and was known for the routine called the Incomplete Sentence where Moreland played straight man. It involved the two comedians cutting each other off in mid-sentence in an attempt to top the other one. "Say, did you see…?" "Saw him just yesterday…didn't look so good". When Carter died in 1946 Mantan found other partners to fill the void, such as Nipsy Russell.
Work began to dry up for Moreland in the 1950s with the rise of the Civil Rights Movement and Hollywood's forced re-assessment of black images. Moreland along with others were considered negative stereotypes to be avoided. In 1953 he hosted a short-lived variety show on TV called "Club Mantan", but as I said it was short lived. In 1957 he appeared in a black production of Samuel Beckett's "Waiting for Godot" as Estragon (Gogo) on Broadway to rave reviews, but it didn't matter. The industry was soured on Moreland's kind.
One bright spot in that decade was in 1955 when Shemp Howard of the Three Stooges died (unless you were a Howard). There was serious talk of replacing Shemp with Mantan, but obviously that was only serious talk. So it was back to the chitlin circuit for Moreland. He recorded a few XXX party records; one where he popularized a bit called "Ain't My Finger (the routine revolves around two people in bed and one says to the other to stop playing and 'get your finger away from my butt', at which the other replies 'I ain't playing and that ain't my finger.') The gag was so popular it was sampled by the Beastie Boys and reference on the animated show "Archer", but mostly it was just a lot waiting for something to happen for Mantan.
It got to the point where in 1959, Moreland made an apology for what he'd done. Going on record he stated he would "never play another stereotype, regardless of what Hollywood offers. The Negro, as a race, has come too far in the last few years for me to dash his hopes, dreams, and accomplishments against a celluloid wall, by making pictures that show him to be a slow-thinking, stupid dolt…Millions of people may have thought that my acting was comical, but I know now that it wasn't always so funny to my own people."
This apology also didn't matter. His career languished for decades. Mantan suffered a stroke in the early 60s, but survived and found whatever work available in a slight resurgence as older generations began to forgive and the newer generation had no knowledge. He was seen in TV commercials and a couple of low budget horror films, but the resurgence was not to last. On September 28, 1973 Mantan Moreland died of a cerebral hemorrhage.
By Darryl "D'Militant" Littleton
www.darryllittleton.lol
Mantan Moreland
'Terminator Genisys' Avalable Blu-ray And DVD Nov. 10th & Digital HD Oct. 20th!
By franknitti1
Method Man Stars In New Comedy Film Titled '#Lucky Number'!
About author / Humor Mill
On This Day In Comedy… In 2008 'Showtime At The Apollo' Aired Its Last Episode In Syndication!
By Humor Mill / June 20, 2016 / Business
On This Day In Comedy… In 1955 Comedian Paul Rodriguez Was Born!
By Humor Mill / January 22, 2016 / Business


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State secessionist movements are long shots at best, but New Yorkers pushing for a breakup between the Big Apple and upstate are counting on the very real possibility of a constitutional convention to boost their odds.
Voters will decide in November whether to hold a statewide constitutional convention in 2019, thanks to the New York State Constitution, which allows for such an event every 20 years.
It's a rare opportunity that the Divide NYS Caucus hopes to seize.
The caucus wants to lift upstate New York's struggling economy by reorganizing the state into two or even three independent regions. Such a division could be accomplished at the convention without the approval of the governor or the state Legislature.
A Siena College poll released May 24 found 62 percent of those polled favor the convention, while 22 percent oppose it, although two-thirds have heard "nothing at all" about it.
That's because the opposition is formidable. Organized labor and the New York State Alliance for Retired Americans already have launched campaigns urging voters to nix the convention, warning that delegates would have the power to gut public pension benefits and collective bargaining rights.
Gov. Andrew Cuomo has said he supports a constitutional convention while also expressing reservations about how it might look in practice.
If voters approve the convention in November, a year later they would select three delegates from each of the state's 63 senatorial districts and 15 at-large delegates. Any amendments passed at the convention would go before the voters for final approval in November 2019.
Even though the constitution allows for a regular convention, New York has not held one since 1967, when the state Legislature called it. The last one called by voters was in 1938.
For upstate advocates of a split state, the convention may come as their best chance to pull off a Brexit-style departure from New York City.
The Divide NYS Caucus several years ago hit on the idea of forming autonomous regions within the state that would be led by their own governors and legislators instead of seeking approval from the Legislature and Congress to form a new state.
The goal is to improve the economic prospects of upstaters, who complain that the state's high taxes and onerous regulations have scared away jobs as companies flee to states with more business-friendly climates.
In December 2014, Mr. Cuomo declared a statewide ban on hydraulic fracturing, effectively halting any natural gas development stemming from the rich Marcellus Shale in the state's southern tier and fueling secession talk, including calls for the region to split off and join Pennsylvania.
Wisconsin has a constitutional convention provision that requires approval of the Legislature and then a statewide referendum. So it seems possible for Wisconsin to do what New York may do and, say, eject Milwaukee and Madison from this state.
As with New York, neither Madison or Milwaukee represents this state. Milwaukee and Madison are the reason the unqualified Tony Evers is governor and not Scott Walker. Without the Axis of Evil, Walker would have been reelected with 56 percent of the vote, which is a larger margin than Walker ever got in getting elected once and reelected twice.
Does this mean that everyone who lives in Milwaukee or the People's Republic of Madison is an idiot liberal? No. But those people who aren't have zero say in government in Dane County or the city of Milwaukee. They are victims of taxation without representation because their representatives don't agree with them. And I must say that those from Madison and Milwaukee who will oppose being seceded are perfectly happy being represented by Democrats and liberals, and have zero interests in the contrary views of their few non-liberal neighbors.
The priorities of those elected by voters in Madison and Milwaukee have rarely matched the views of voters in the rest of the state, but with time those differences have done nothing but expand. Evers and his attorney general are about to embark on an unconstitutional crusade to take guns away from people without due process or the least consideration of their constitutional rights, and that's just the start. The rest of the state may be fine with Democrats' ruining Madison and Milwaukee as they have in Milwaukee's case and they are doing in Madison's case. They should not be allowed to ruin the part of the state where real Wisconsinites live.
I had no idea about this situation. Thank you for the heads up!


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L'apolipoprotéine D (ApoD) est une protéine retrouvée à la surface des lipoprotéines de haute densité (HDL) , qui transportent le cholestérol vers le foie.
Les lipoprotéines sont en effet des complexes responsables du transport du cholestérol dans le sang et sont formés de lipides et de protéines. Les composantes protéiques sont retrouvées à la surface du complexe: les apolipoprotéines, qui varient selon le type de lipoprotéine (HDL, LDL, VLDL etc.).

Comme les autres apolipoprotéines, l'ApoD participe au transport de molécules hydrophobes. Sa structure est néanmoins différente des autres apolipoprotéines: elle ressemble plutôt à celle des lipocalines, une famille de protéine ayant un rôle dans le transport de petites molécules hydrophobes .
L'ApoD peut ainsi lier plusieurs molécules, appelées alors ligands, tels que le cholestérol, la progestérone, la prégnénolone, la bilirubine et l'acide arachidonique.

Elle est surexprimée dans plusieurs maladies neurodégénératives telles que la maladie d'Alzheimer, la maladie de Niemann-Pick, de la méningo-encéphalite, du syndrome de Guillain-Barré ainsi que chez les patients atteints de démence, de schizophrénie ou ayant eu un accident vasculaire cérébral.

Propriétés
L'ApoD est une protéine composée d'une chaîne de 189 acides aminés. Cette structure primaire correspond à celle des autres apolipoprotéines. Néanmoins, sa structure tertiaire tridimensionnelle s'apparente plutôt à celle des lipocalines. En effet, elle a une forme cylindrique appelée barillet bêta, dont l'une des extrémités est fermée. L'autre côté, ouvert, présente les sites de liaison aux molécules hydrophobes qu'elle transporte.
Le poids moléculaire de l'ApoD est estimé à 29 kilo Daltons (kDa) mais peut varier en fonction de sa glycosylation. L'ApoD est en effet une glycoprotéine, c'est-à-dire qu'un glucide (sucre) a été ajouté à sa structure primaire lors de la production de la protéine. La glycosylation représente ainsi environ 18 % de la masse de l'ApoD.

Le gène qui code l'ApoD est situé sur le chromosome 3 chez l'humain et sur le chromosome 6 de la souris. Le promoteur du gène est régulé par les hormones stéroïdes tels que les androgènes, les œstrogènes et les glucocorticoïdes, en plus d'être influencée par le taux de prolifération cellulaire. Il a en effet été démontré que l'ApoD était surexprimé dans les cellules sénescentes ou non prolifératives .

Contrairement aux autres apolipoprotéines qui sont exprimées dans le foie et les intestins, l'ApoD n'est généralement que faiblement exprimée dans ces tissus. De plus, l'expression de l'ApoD varie selon l'espèce. Ainsi chez l'humain, le singe et le lapin, on retrouve une expression importante de l'ApoD dans le cerveau, les glandes surrénales, les reins, le pancréas, le placenta, la rate, les poumons, les ovaires, les testicules et les nerfs périphériques. Par contre, chez la souris et le rat, l'ApoD est principalement exprimée dans le système nerveux central, soit dans la moelle épinière, le cervelet et le cerveau

Rôles
Chronologiquement, l'apolipoprotéine D a d'abord été identifiée comme un composé des HDL puis analysée dans les fluides kystiques mammaires (cancer du sein). La protéine était alors nommée GCDFP-24 et sa caractérisation a démontré qu'elle liait la progestérone avec une grande affinité, ainsi que la prégnénolone, ce qui lui attribuerait un rôle dans le transport de ces hormones dans les glandes mammaires
Parallèlement, lors de ses premières caractérisations, l'ApoD était considérée comme un composé des HDL: on lui attribuait un rôle de transporteur du cholestérol, des tissus périphériques au foie.

De plus, il semble que l'ApoD ait un rôle dans la régénération des nerfs endommagés et qu'elle serait un suppresseur de tumeurs dans certains cancers comme celui du sein ou de l'œsophage

Notes et références

Apolipoprotéine

redpajama_set_name: RedPajamaWikipedia


Registrations for the PBI Baseball League 2010 fall season are now being taken.
The PBI Baseball League plays on Sundays in the fall. Teams are able to play on other days as per agreement by both coaches, but be aware coming into the league that this is designed for Sunday play. The majority of the teams in the league come from Bergen, lower Rockland, and Passaic Counties.
NOTE – teams should pick the appropriate level based upon the skill of their players, not where they are from. It's possible to have players from a couple of different towns and still be a AA or A-level team.
9U through 14U will use a pitch count through all three divisions. 8U will have a 2-inning per pitcher rule. For the sake of clarification, an inning pitched consists of 3 outs. There is no pitch count at the high school levels.
AGE CUTOFF – The age cutoff for all levels of the PBI Baseball Leauge's 2010 Fall Season is April 30, 2011. Whatever age a player will be on April 30, 2011 is that player's "league age." A player may "play up" an age level; he cannot "play down" under any circumstances.
REGULAR SEASON – The regular season will begin on Sunday September 12 and continue through Sunday October 31.
PLAYOFFS – The top four teams in each skill division of each age level will meet in a single elimination tournament. The first round will take place on Sunday November 7 and the Championship game will take place on November 14. The PBI Baseball League provides individual awards for players on the first and second place teams.
COST – $225 per team. The league fee includes FREE INSURANCE for teams that are in need. PBI cannot hold a space for you; teams are taken on a first-paid-first-served basis.
INSURANCE – FREE from PBI. If you need insurance, contact Jim Monaghan.


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AUSTRALASIAN PANCREATIC CLUB (APC)
An association is hereby constituted, named "The Australasian Pancreatic Club" (APC). The association will be housed in the office of the Secretary General.
Duration and dissolution
(i) The association is established for an indefinite term.
(ii) In the event of the dissolution of the APC, the council is responsible for the liquidation of the association. The remaining assets will be distributed according to the decision of the members for future use exclusively for the same goals as those pursued by the APC.
(i) The APC is a non-profit making organisation with the following aims:
(A) To promote communication between basic and clinical scientists interested in the pancreas and its disorders.
(B) To promote and organise an annual scientific meeting devoted to all aspects of the pancreas.
(C) To promote scientific, epidemiological and clinical research into pancreatic function and into the prevention, diagnosis and therapy of pancreatic diseases.
(D) To establish scholarships and promote postgraduate education and training.
(E) To support other meetings concerning the pancreas organised by members of the APC.
(F) To disseminate information about APC activities, and publish such educational matter as the APC council may consider desirable.
(ii) Central funds will be retained to serve the APC to fulfil its scientific and social purposes.
(i) Membership of the association is open to anyone with an interest in the pancreas. The membership shall remain valid as long as the membership fees suggested by the Executive Council and approved by the General Assembly are paid. Only members of the APC may vote at the annual General Assembly.
(ii) Any liability of the association is strictly limited to its assets. Neither the members of the association nor the members of the Council shall be subject to payment of association debts to any extent whatsoever.
(i) The General Assembly of the association is the highest organ of the APC. It consists of the members of the APC.
(ii) The General Assembly decides on the election of president, secretary, co-secretary (optional), treasurer and councillors of the APC, accounts, annual fee, alteration of the constitution, co-operation with other societies, and dissolution of the association.
(iii) A quorum of the General Assembly exists if at least 30% of the members participating in the annual APC meeting are present.
(iv) Voting by proxy registered in writing is permitted on a motion previously circulated with the agenda. Each member present or voting by proxy is entitled to one vote.
(v) Decisions of the General Assembly (other than those otherwise stipulated) will be agreed by a simple majority of those voting in person or voting by proxy. Decisions to alter the constitution will require a two-thirds majority of those voting in person or voting by proxy on said motion. The decision on the dissolution of the association will require a two-thirds majority of all members.
(i) The executive council of the APC will consist of the President, the President elect, the past President, the Secretary General (In some cases two Council members may fill this role), co-secretary (optional), and a minimum of four general councillors. The President will preside over the APC for one year and shall chair all meetings of the Council or can delegate this to the Secretary General.
(ii) The Council will nominate candidates for those vacancies that exist. The General Assembly finally approves these candidates or nominates alternative candidates, according to the rules stipulated in Article V.
(iii) At least two of the general councillors should be basic scientists. The term of each general councillor is limited to 3 years and can only be re-elected after approval from the Council. In the event of an unexpected vacancy, the Council shall nominate a substitute for the remainder of the year, to be approved by the Council.
(iv) The Secretary General will serve for a maximum term of 5 years. The Secretary General cannot be re-elected.
(v) The Council has the option to co-opt potential General Council members not present, or nominated, at the time of Council elections.
(i) The President and the site for forthcoming meetings shall be decided by the General Assembly strictly 1 year in advance after nomination by the council. The president will be responsible for the organisation of the annual meetings as detailed in Article X.
(ii) The presidency should alternate between a basic and clinical scientist.
(iii) The President will serve for a maximum of 2 years.
(iii) A President-Elect will be nominated by the Council and approved by the General Assembly at the time the President has served for 1 year.
(i) The Secretary General will attend to the affairs of the association and the Council and will keep minutes of all its meetings. The Secretary General shall inform each Member of the APC details of the decisions taken at the General Assembly, within three months of each meeting by posting on the website.
(ii) The Secretary General or Treasurer, if not a shared function, is entrusted with the funds of the APC, their collection, their safe-keeping, and disbursement at the direction of the Council. The budget and audited annual accounts will be prepared by the Secretary General and must be presented to the Council and General Assembly every year. The Secretary General will have the authority to sign individually according to rules to be set up by the Council.
Responsibilities of the Council
The APC is managed by the Council. The Council decides on all matters not specifically assigned to the General Assembly. The Council notably has the following responsibilities:
(A) Administration of the APC business.
(B) Organisation of the annual APC-meeting as detailed in Article X.
(C) Delegation of responsibilities to sub-committees or working parties as appropriate.
(D) Approval of the accounts.
(E) Preparation and executing of rules and regulations for the management of the APC.
Quorum and voting of the Council
(i) A quorum of the Council exists if fifty percent (50%) of the nominated representatives on the Council are present.
(ii) Voting by proxy registered in writing is permitted on a motion previously circulated with the agenda. Each representative on the Council present or voting by proxy is entitled to one vote.
(iii) Decisions of the Council (other than those otherwise stipulated) will be agreed by a simple majority of those voting in person or those voting by proxy. In the event of an equally divided vote, the President shall have a casting vote. The President may empower the Secretary General to hold a postal vote on motions circulated in writing. In this case, a quorum of the Council exists if 50% of the Council have exercised their voting right.
The Council may form sub-committees to undertake specific tasks and duties designated by the Council (Article VII C). All sub-committees must report and are answerable to the Council. The Council may nominate to the sub-committees persons who are not member of the Council. Such persons may attend meetings of the Council by invitation, but may not vote.
Organisation of the APC meetings
(i) The President (clinician or basic scientist) and President-elect (basic scientist or clinician) have overall responsibility for the APC meeting.
(ii) The organisation of the annual meeting is delegated to the President at the venue selected by the General Assembly, subject to guidelines prepared by the Council.
(iii) The President must report on the progress of the meeting to Council as often as the Council may require.
(iv) The meetings shall normally last a maximum two days.
(v) The scientific content of the meeting remains the responsibility of the Council which may establish sub-committees to design the programme.
(vi) Scientific communications and abstract selection is the responsibility of the Council.
(vii) Abstracts in English of no more than two hundred and fifty words should be sent to the General Secretary and/or co-secretary some six weeks before the meeting. Only studies unpublished at the time of submission of the abstracts will be accepted. An outlined programme of the meeting should be circulated to all registered participants in advance of the meeting.
(viii) A registration fee is payable by all participants at the meeting, the amount to be determined by the President and approved by Council at least 6 months before the meeting.
Article XI
Change of Statutes
Revised Statues ratified at APC Council Meeting.


New York Giants running back Saquon Barkley works out during NFL football training camp.
A total of 34 former Penn State football players are on NFL teams this season, including six rookies who made active rosters.
Penn State players appear on 23 NFL rosters, with Pittsburgh and Miami featuring three each.
Joining the six rookies on active rosters are four on practice squads: Saeed Blacknall and Jason Cabinda (Oakland), Curtis Cothran (Minnesota) and Grany Haley (New York Giants) made practice squads.
Saquon Barkley made a point during training camp to start conversations with every one of the New York Giants' offensive lineman. He suggested going to dinner with them. He asked for their advice.
In addition, former Penn State lacrosse player Chris Hogan returns to the New England Patriots. Former basketball player Ross Travis is on the Indianapolis Colts' injured-reserve list.


If you're looking for a place to get away, look no further than Valigny. Whether you're planning to stay for a night or for the week, the area around Valigny has accommodations to fit every need. Search for hotels in Valigny with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Valigny hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Valigny hotel deals are here with our lowest price guarantee.
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Stephen Leahy, International Environmental Journalist
Discovering Global Environmental Interconnections
Help Sustain Independent Environmental Journalism
Award-winning Journalist and Author
HomeBoost Food Production by Reducing Enviro Impacts
Boost Food Production by Reducing Enviro Impacts
01/05/2008 01/05/2008 Stephen Africa, Agriculture/Food, CLIMATE CHANGE/GLOBAL WARMING, Energy, ENVIRONMENT, Global Issues and Perspectives, News, Science/Tech, sustainabilityIAASTD, robert watson
Credit:I
JOHANNESBURG, Apr 15 (IPS) – Over the past few years, Robert Watson has had what must qualify as one of the world's tougher assignments: heading an initiative to help agriculture cope with the substantial challenges it faces presently, and the even bigger hurdles ahead.
The three-year International Assessment of Agricultural Science and Technology for Development (IAASTD) has sought to evaluate agricultural knowledge across the spectrum, with the help of governments, civil society, the private sector, and hundreds of experts.
Watson initiated the project while chief scientist at the World Bank; he currently serves as director of the IAASTD — also as chief scientist at the British environment and agriculture department.
The findings of the assessment are being formally presented Tuesday, this after they were reviewed at an intergovernmental plenary held in Johannesburg, South Africa, from Apr. 7-12. IPS environment correspondent Stephen Leahy chatted to Watson at this meeting about the landmark IAASTD.
IPS: What is the significance of the IAASTD findings for global food security?
Robert Watson (RW): The significance of the IAASTD is that for the first time governments from the developed and developing countries, civil society, scientific authors from natural and social sciences all worked together to address the critical issue of how to get affordable and nutritious food in way that is environmentally and socially sustainable.
IPS: The IAASTD clearly states that business as usual in agriculture is not an option. Why is this the case?
RW: The IAASTD builds on the findings from two previous assessments. The Millennium Ecosystem Assessment found that 15 of the planet's 24 natural ecosystems are in trouble or in decline, in large measure due to degradation of land and water — mainly because of agriculture. The Intergovernmental Panel on Climate Change concluded that agriculture is a major contributor to human-induced climate change, and climate change will have a major impact on agricultural productivity.
If we only focus on boosting food production it will only come at the expense of further environmental degradation.
IPS: What do IAASTD findings say about the current food prices, which are at record highs?
RW: There are many factors involved in food prices — climate variability resulting in declines in harvests in some areas, higher energy costs, biofuel production and speculation on the futures market. Now is the time to ask: how can we increase food production, keep food affordable and ensure farmers can make a decent living? The IAASTD is our best attempt to answer that important question.
For the full interview please see Q&A
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