Photo: clry2 via Creative Commons.
Dr Robin Hesketh, author of Introduction to Cancer Biology, looks at the impact of genetic sequencing on finding a cure for leukaemia.
In 2003 it was a sensation. No really – it's probably true that in medicine only the first human heart transplant operation back in 1967 has generated as much publicity. That was in the pre-web dark age but, nevertheless, the South African surgeon Christiaan Barnard was immortalized as a global hero: even the patient's name was on everyone's lips (Louis Washkansky if you're struggling to recall) and you can re-live the whole event at the Groote Schuur Hospital museum in Capetown. But, although 2003 was just a decade ago, in today's world sensations fade almost with the following dawn, whether they are pop groups or life-changing scientific advances.
So if now you mention "The Human Genome Project" to a man on the Clapham omnibus you are likely to elicit only a puzzled look. What happened in 2003 was of course that the genetic code – that is the sequence of bases in DNA – was revealed for the entire human genome. And an astonishing triumph it was, not least because, in contrast to almost everything else in history with a major British component, it was completed within schedule and under cost.
…sequencing speed has gone up by 100 million times whilst, almost unbelievably, the cost has dropped by a factor of 10,000.
However, even more remarkable is what happened next. The ensuing decade has brought technical advances so breathtaking as to almost overshadow the original human genome project itself. This quite staggering revolution has seen the introduction of fully automated, high throughput flow cells that simultaneously carry out hundreds of millions of separate sequencing reactions – just say that slowly. In the jargon it's called 'massively parallel sequencing'. The upshot of this stunning technology is that sequencing speed has gone up by 100 million times whilst, almost unbelievably, the cost has dropped by a factor of 10,000. Even computing science can't match that progress!
One consequence of this incredible, though relatively unpublicised, revolution is that genomes can be now be sequenced on an industrial scale and in the years to come that is going to impact on every facet of mankind's existence. Thus far the field of cancer has been the foremost recipient of this technological broadside with thousands of tumour genomes now sequenced. This has unveiled the almost incomprehensible panoply of genetic changes that cells can sustain and yet emerge still capable of proliferating. One of the first cancer genomes to be sequenced was that of a female who had died from leukemia. The work was carried out by The Genome Institute at Washington University in St. Louis, Missouri and since then, under its Director Richard Wilson, this group has continued to be a world leader in genomics and in particular in unravelling the extraordinary complexity of the group of cancers collectively called leukemias.
Wilson and his colleagues know, of course, that they are at the forefront of the most extraordinary transformation in medicine – because eventually it will affect everyone –though Rick Wilson himself is as improbable a revolutionary as you could imagine: a gentle, soft-spoken American, he's what on this side of the pond would be called a thoroughly nice chap.
However, if they had any doubts about the direction in which their science was leading the world, these would have been dispelled when one of their own community, Lukas Wartman, was diagnosed with a very rare form of leukemia. This had first appeared ten years ago when Lukas was a student completing his medical degree at Washington University, and at that time it had been treated with chemotherapy and a bone-marrow transplant.
In the following years, Dr. Wartman had pursued his career goal of becoming a practicing oncologist specializing in leukemia until, in July 2011 the disease returned and he went into relapse. As his condition deteriorated rapidly and only one outcome seemed possible, those treating him turned in desperation from conventional approaches to local expertise. They applied genomic analysis to his cancer cells. From the vast number of disruptions identified, one in particular stood out: an abnormally expressed gene that had previously been associated with other types of leukemia but is very rare in the form Wartman had developed.
By an unlikely chance there is a drug available that can knock out the activity of the protein made by that gene. Its effect was phenomenal, restoring the normal blood count and achieving complete remission. This wonderful outcome does not mean that Dr. Wartman is cured for life – but for now he is alive and well – and a co-author of the group's latest paper – on leukemia.


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The word snorkeling is a noun. Snorkeling means (1) skin diving with a snorkel.
The following articles and web pages elaborate on the word snorkeling.
Visit this diving equipment manufacturer directory for info about diving equipment and supplies manufacturers and wholesalers in the USA. The photo on this page shows a face mask for scuba diving or snorkeling.
Known for their dramatic limestone cliffs and caves, the Turks and Caicos islands are grouped around a shallow underwater plateau that provides excellent scuba diving and snorkeling conditions.
Located in the Pacific Ocean, Bora Bora is a spectacular island that is part of French Polynesia. Its two peaks, Mount Pahia and Mount Otemanu, are surrounded by a lagoon and a barrier reef, creating the perfect snorkeling or scuba diving environment.
The Florida Keys have sparkling water and white sand beaches. Swimming, snorkeling, and diving are popular. Islamorada is considered the sportfishing capital of the world. Driving down the 127.5-mile Overseas Highway to Key West is an adventure. Key West, with its palm-lined streets, is the southernmost city in the continental USA. Here, Key Lime Pie is a favorite.
The following articles provide recent snorkeling-related news.
The only things to buy on South Caicos are experiences: snorkeling in its glassy, cerulean waters; seeing wild donkeys wandering along the side of the road; staring in awe at the inky night sky heaving with stars.
By Sophie Friedman, Contributor. Forbes. Monday, 1 Apr 2019 17:58:00 -0400.
Smithsonian. Tuesday, 26 Feb 2019 15:40:54 +0000.
The following digital image illustrates the word snorkeling.


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Introduction to Sports Law: Current Issues Facing Professional and Pre-Professional Athletes Introduction to Sports Law: Current Issues Facing Professional and Pre-Professional Athletes
Due: By 11:59 p.m. Monday, December 21, 2015
Submit Electronically: Upload Word Document to Canvas
The exam mode is TAKE HOME and OPEN TO ALL COURSE-COVERED MATERIALS (defined below).
The examination appears in its entirety following the instructions.
There is one (1) essay, two (2) multi-part multiple choice and two (2) short answer questions. The essay is worth a total of 20 points, the short answer questions are worth 8 points each (16 total) and the multiple choice parts are worth 1 point each (14 total). The examination is worth a total of 50 points. You must answer each question. Your written answers may not exceed 2,250 total words. You may divide your word count as you deem appropriate, although there are recommended word amounts at the beginning of each question. Please place citations in-line or as footnotes, which will be included in the word limit. A table of contents is unnecessary.
Support your arguments with the maximum number of citations to the Course-Covered Materials, as defined herein. While taking this examination you must consult and rely exclusively on the assigned course materials — including any Readings, Canvas materials, your own Class Notes from any class session, outlines or your group�s materials (�Course-Covered Materials�). You may not affirmatively cite to, or rely on, any source outside of those materials. Use the Course-Covered Materials to provide the maximum number of relevant precedents/citations for each of your answers to each part of each question. Citations needn�t be in Bluebook format and abbreviations may be used, so long as it is clear what you are referring to.
Collaboration with other students is strictly prohibited. YOUR ANSWERS MUST BE ENTIRELY YOUR OWN WORK. You may not discuss the examination with anyone, either while in possession of the exam or thereafter until after the exam period ends.
Please be aware that all names and events used within this exam, even though perhaps similar to real individuals or events, are fictitious. You should not assume any facts beyond those given, unless you explicitly state those assumptions within your answer.
Question ONE � [1250 Words Recommended] [20 points]
The following question relates to Commissioner�s Authority in the NFL. Students should review the materials relating to the Course-Covered Materials in Weeks 1-3.
Max Yardley is the starting quarterback for the NFL�s Virginia Sharks, and has been one of the premiere quarterbacks in the league for the last four seasons. The Sharks made the playoffs the last four years, the AFC Championship game three times, and won a Super Bowl in 2014. The 2014 season saw Yardley connect for ten touchdowns with his star wide receiver, Bill Overs, on the way to Yardley winning the league MVP award.
In late February after the 2014 Super Bowl, an ESPN news report surfaces that Yardley played in three season-long fantasy football leagues during the 2014 season, two of which were for money. Yardley owned himself in all of these leagues, and reportedly won $10,000 among the two for-money leagues. Yardley also played in one of the new DraftKings weekly leagues, making $25,000 over the course of the season, again playing himself every week. Yardley also owned Overs in both of the for-money season-long fantasy leagues, and in the DraftKings league. The NFL allows players to win up to $250 per contest on NFL fantasy leagues (for purposes of this exam: $250 total per week in all weekly leagues combined, and $250 total per season in all season-long leagues combined). Federal and Virginia law allow playing fantasy sports for money, but the Virginia Attorney General is currently investigating the legality of fantasy sports.
Commissioner Badchoices began an investigation into this conduct shortly after the story broke, hiring outside counsel to do a full investigation. This investigation confirmed the rumored amounts of money, and revealed information concerning Yardley�s Offensive Coordinator, Will Booker. The independent report found that Booker was a recovering gambler, and he had exchanged several e-mails with Yardley discussing plans to focus on Overs in the play-calling, and pad Yardley and Overs statistics and fantasy points. The report did not find Overs to be involved in these dealings.
Badchoices released his decision about the punishment for Yardley in late March. Invoking his �best interests� and �conduct detrimental�/�integrity of the game� authority, he suspended Yardley for the first five games of the 2015 season. In the publicly-available decision, Badchoices discussed how this conduct �degraded public confidence in and respect for the National Football League,� citing the risks to all professional sports leagues from fears of gambling tainting on-field performance. Yardley appealed this finding under the league-mandated arbitration, and Badchoices upheld his own decision. Badchoices has not yet announced any punishment for Booker.
If Yardley and the NFLPA appealed such a Final League-Arbitration Decision (that upheld the Commissioner�s Suspension) to a Federal Court to seek a Vacatur of the League�s Final Arbitration Decision, is the NFL Player and his Union likely to survive a Motion to Dismiss? Prepare the Memo as counsel to the NFLPA.
Note: In your response, please prepare the Memo in the form described in the Book at pages 31�32, and support your Memo�s conclusions with the maximum citations to the Course-Covered Materials.
Course Textbook: The required text is Professor Peter A. Carfagna�s Sports and the Law: Examining the Legal Evolution of America�s Three �Major League� Sports 2d Ed. (West 2011), available in the Law Coop, or online at Amazon.com or West Thompson in hard copy and e-book form.
Question TWO — [10 points]
The following questions relate to Age Eligibility and Free Agency Rules in the MLB, NFL and NBA. Please select the most appropriate answer for each question. Students should review the materials relating to the Course-Covered Materials in Weeks 4 & 8.
A. Rick Fillion, the top-rated high school pitcher in the country, is a junior at Essex High School. Rick has been scouted by most of the top 25 college baseball programs in the country, and even by several MLB teams.
Part I: Rick wants to know when he is eligible for the MLB Draft.
Rick is eligible for the MLB Draft after each year he completes in college.
Rick is eligible after he graduates high school, after his junior year of college, after he graduates community college and after his senior year of college.
Rick is only eligible after he graduates high school and after he graduates college.
Part II: After being selected #1 Overall by the Texas Rangers, Rick makes his debut as the Opening Day Starter for the Rangers in 2018. Ignoring whether or not Rick earns Super Two status, and assuming he is not sent down to the minors at any point, when will Rick be eligible for Free Agency?
Rick is eligible for Free Agency after his fourth major league season.
Rick is eligible for Free Agency after his sixth major league season.
Rick is eligible for Free Agency after his eighth major league season.
B. Tony Weatherly is the top-rated NCAA scholarship basketball freshman in the country and attends The Ohio State University. Tony has led The Ohio State to the National Championship game and is expected to be taken first overall by the Philadelphia 76ers.
Part I: Is Tony eligible for the upcoming NBA Draft?
No, not until Tony completes two years in college.
No, not until Tony graduates college.
Yes, under the �one and done� rule of the NBA CBA, a student-athlete is eligible after only one year of collegiate basketball.
Part II: After being selected #2 overall by the Miami Heat, Tony signs his first NBA contract. In accordance with the NBA CBA and slotting system, how long will Tony�s first contract be?
The contract is for two years, with no team options.
The contract is for two years, with two team options (making it four total years if the options are exercised).
The contract is for six years.
Part III: After spending four long, losing seasons with the Miami Heat, Tony�s first contract has ended and he wants to leave the team. Is Tony eligible for Unrestricted Free Agency yet?
No, Tony would only be eligible for Restricted Free Agency, and could only receive Offer Sheets from other teams that the Heat would have the right to match.
Yes, Tony would be free to sign for any team in the league.
No, Tony�s rights belong to Miami indefinitely.
C. Cullen Mount, the top rated high school Quarterback in the country, is a senior at Essex High School. Cullen has been scouted by every major college football program in the country, and has accepted a Scholarship Offer from the University of Virginia.
Part I: Now that Cullen has begun his collegiate career in August 2015, when will Cullen first be eligible to enter the NFL Draft?
Cullen would be first eligible one year after graduating high school.
Cullen would be first eligible two years after graduating high school.
Cullen would be first eligible three years after graduating high school.
Part II: Cullen graduates from UVA and is selected 1st overall by the Minnesota Vikings in the May 2019 NFL Draft. In accordance with the NFL CBA and the slotting system, for how long will Cullen�s first Team Contract extend? Does the team have any rights to the player at the end of the contract? When is the earliest Cullen will be eligible for Free Agency?
Cullen�s first contract would be for three years, and the team would possess a fourth- and fifth-year option. The team could also designate Cullen as a Franchise Player for three more seasons. The earliest Cullen could be a Free Agent is after three seasons, while the latest (assuming no extensions) would be after eight seasons.
Cullen�s first contract would be for four years, and the team would possess a fifth-year option. The team would also have the ability to designate Cullen as their Franchise Player for three more seasons. The earliest Cullen could be a Free Agent is after four seasons, while the latest (assuming no further contract extensions) would be after eight seasons.
Cullen�s first contract would be for five years, and the team would possess no further options of tags. Cullen would be eligible for Free Agency after five seasons no matter what.
D. Establishment of Free Agency
Part I: Rick Fillion can thank which of the following cases for the establishment of Free Agency in the MLB?
Toolson v. New York Yankees
Flood v. Kuhn
Messersmith-McNally Arbitration Grievance
Part II: Tony Weatherly can thank which of the following cases for the establishment of Free Agency in the NBA?
NBA v. Williams
Robertson v. NBA
Caldwell v. ABA
Part III: Cullen Mount can thank which of the following cases for the establishment of Free Agency in the NFL?
McNeil v. NFL
Powell v. NFL
Mackey v. NFL
Question THREE — [4 points]
The following questions relate to the Course-Covered Materials in Weeks 5-7. Please select the most appropriate answer for each question.
Part I: Unlike the NFL and NBA, the MLB enjoys this in relation to the �business of baseball,� in limited circumstances�
Antitrust Exemption
Non-Statutory Labor Exemption
�Collective Bargaining Agreement� Exemption
Part II: Each of the major leagues are given protection from antitrust scrutiny by this, established by �301 of the Labor Management Relations Act.
Non- Statutory (or �CBA�) Exemption
Statutory Labor Exemption
Part III: Which of the following leagues are considered a single entity for the purposes of antitrust laws?
NFL (as established in American Needle v. NFL)
MLS (as established in Fraser v. MLS) because each team is owned by the league, rather than individual owners.
NBA (as established in American Needle v. NFL)
Part IV: American Needle, Inc., a manufacturer of headwear merchandise, sued the NFL over their exclusive licensing deal with which major apparel company?
Question FOUR � [500 words recommended] [8 points]
The following question relates to the Course-Covered Materials in Weeks 10 & 11.
Assume you are a consultant to Michael Jordan and that Qiaodan Sports has begun distributing their products in the United States. Additionally, the Chinese-based sporting goods company has begun opening new stores in Chicago, and selling products bearing the Qiaodan logo. Michael Jordan has filed suit for damages and an injunction against Qiaodan.
Please list MJ�s �best arguments� in his favor, in priority order of �best arguments� first, as described in the Book at pp. 31-32, and support your Memo�s conclusions with the maximum citations to the Course-Covered Materials.
Please next list, (in the same Priority Order of "Best Arguments/Headings� first) the bases on which the Qiaodan should be permitted to continue operating. Please again support your Answer with the maximum number of citations from the Course Covered Materials.
Question FIVE � [500 Words Recommended] [8 points]
You are the Senior Staff Attorney for Judge Claudia Wilken and you are working with her on the Consolidated Alston/Jenkins Case, in which the players represented by Jeff Kessler have requested �Free Agency� for student-athletes, per Kessler�s theories of antitrust law that proved successful in the Freeman McNeil case.
She has asked you to assist her as she prepares to rule on the NCAA's Motion for Summary Judgment.
Please list The NCAA's "best arguments" on the basis of which the Judge should grant the Motion, in priority order of "best arguments� first, as described in the Book at pp. 31-32, and support your Memo�s conclusions with the maximum citations to the Course-Covered Materials.
Please next list, (in the same Priority Order of "Best Arguments/Headings� first) the bases on which the Judge should deny the Motion and allow the Alston and/or the Jenkins Case to continue past Motion into the Discovery stage of the Case(s). Please again support your Answer with the maximum number of citations from the Course Covered Materials.
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Most Mysterious Ancient Sites We Still Know Almost Nothing About
Much of what we know about ancient cultures today comes from the pictures and written documents left behind. In some cases, artefacts can leave clues as to who the people were that created ancient monuments that are now no more than ruins, but in other instances, there are more questions than answers.
Historians, archaeologists, and geologists have many theories about the ruins on this list, but they are just that: theories. These ancient ruins hold more questions than answers and in some cases, experts are not even sure about how such sites could exist.
Humans first settled into permanent towns, farmed and then built temples, in that order, starting in 8,000 B.C. Or did they?
An amazing archaeological discovery made in 1994 at Gobekli Tepe, a rural area of Turkey, has blown that hypothesis apart, prompting new questions about the evolution of civilization.
Radiocarbon dating puts Gobekli Tepe at between 10,000 and 11,000 B.C., making it to be generally considered the oldest religious structure ever found. The ancient site contains stone structures and pillars featuring carvings of various predatory animals. The construction of the stone pillars (some weighing nearly 20 tons) remains a mystery since they were erected at a time when humans were thought to be simple hunter-gatherers.
Easter Island is one of the most remote inhabited islands on Earth. Here lies one of the world's most famous mysteries – the giant stone statues called Moai. It was first thought that the statues were merely heads, but excavation has shown almost all of them to have bodies. There's a form of hieroglyphic writing on some of the statues but nobody has been able to translate them.
Very few of the statues were ever actually erected; most were left in quarries, or abandoned during transport. Archaeologists don't know why the statues were built, what they signified, how they were transported and erected, or why they were abandoned unfinished.
Qin Shi Huang's tomb
In 1974, farmers in China's Shaanxi province accidentally unearthed one of the biggest archaeological finds of the 20th century — the life-size terracotta army of Emperor Qin Shi Huang (259 B.C. – 210 B.C.).
The intricately carved figures aren't a mystery: Historians know that the clay army was created to defend China's first emperor in the afterlife. What isn't known, however, is where exactly the emperor is buried or what treasures his burial chamber might contain.
The first emperor's final resting place is the most opulent tomb ever constructed in China, according to ancient documents describing its construction. An underground palace, complete with a surrounding "kingdom," the mausoleum is made up of a network of caves. Whether archaeologists will ever have the technology they need to safely excavate the tomb (which also happens to contain extremely high levels of mercury) remains a mystery.
Nazca Lines
Identifiable easily from the air and spread out across desert land in southern Peru, these geometric designs are designated as a UNESCO World Heritage Site.
There are hundreds of them and they range in style from simple shapes to clear line drawings of animals such as monkeys, sharks or lizards. The largest of them spans over 200 metres.
They were created by removing the red stones of the region to reveal the white limestone underneath. Remnants of what appear to be wooden stakes used in their design take some of the mystery out of how someone could create such figures without a bird's eye view, but what was their purpose?
Theories abound from astronomical alignments and directions to water sources to the usual believers in extraterrestrial visitors in need of landing strips.
Another icon of the ancient world, the stone slabs of Stonehenge were erected about 2500 BC. Historians still debate how the large sarsen stones, some of them weighing upwards of 300 tons, were transported from their likely origin 20 miles away.
Another mystery: Why was it built in the first place? Historians have speculated that it may have once been a site for religious ceremonies or designed to be a solar calendar that tracked the passage of the seasons.
Indus Valley Civilization
The Indus valley civilization is perhaps India's most ancient mystery. There are many unanswered questions about this great civilisation that was larger than the ancient Egyptian and Mesopotamian civilisations combined. The secrets behind the identity of the people who created it and their puzzling 4000-year-old Indus pictographic script are yet to be discovered. Also, perhaps the most bewildering fact about this civilisation is that all its major sites went into sudden decline and disappeared more or less simultaneously. There are several theories about why this happened but none of them has been very conclusive.
On a barren hill in northeastern Georgia, USA stands one of the world's most bizarre and mysterious monuments. But it wasn't created during ancient times.
Known as the 'Georgia Guidestones', this stone structure of five 16-feet-tall, 20-ton slabs of polished granite was erected in 1980. A message consisting of a set of ten guidelines or principles is engraved on these slabs in eight different languages. These languages are: English, Spanish, Swahili, Hindi, Hebrew, Arabic, Traditional Chinese, and Russian
It looks like these instructions are for dazed post-apocalyptic survivors attempting to rebuild civilization. The Georgia Guidestones were commissioned by an anonymous group, whose identity remains a mystery.
The lost city of Atlantis has been discovered in the Bahamas, the Greek Islands, Cuba, and even Japan if every claim was to be believed.
First described by the ancient Greek historian Plato in 360 B.C. The mythological island was supposedly a great naval power before sinking into the sea over 10,000 years ago in a catastrophic event.
Archaeologists debate the actual historical existence of the island as well as its most plausible location if it ever actually existed among the many sunken ruins discovered around the world.
But even without definitive proof, Atlantis continues to engage the popular imagination like few other archaeological mysteries out there.
Do you know of any mysterious sites and places that we have missed in this list? Tell us about them in the comment section below.
Enjoyed reading this? Check out more such articles on The Learning Tree blog.
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Do you really want to delete "Electric now has a Mercedes: Mercedes-Benz is entering the era of electromobility"?
(combined power consumption: 22.2 kWh/100 km; combined CO2 emissions: 0 g/km*, provisional figures)2;  Figures for power consumption and CO2 emissions are provisional and were determined by the German Technical Service corporation. The range figures are also provisional. EC type approval and conformity certification with official figures are not yet available. There may be differences between the stated figures and the official figures.
1, 2 Figures for electrical consumption and CO2 emissions are provisional and were determined by the technical service. The range figures are also provisional. EC type approval and conformity certification with official figures are not yet available. There may be differences between the stated figures and the official figures.


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The centerpiece of Hope and Fear will be a sleek Art Deco palace, the Pavilion of the Future. Art Deco, arising in the 1920's and 30's, became a symbol throughout much of 20th Century for all that was considered modern. Its streamlined and dynamic forms derived from an industrial aesthetic that romanticized progress. They summoned up a sense of power, purpose and velocity. As an art style, Deco stands as the West's last commonly held vision of a utopian future. Today, of course, this art form represents a retro-future: one that never came to be. The principle problems of post-modern life do not concern how we'll employ our endless leisure. Robots do not wait upon us hand and foot, nor do we jet from place to place in private rocket ships. Along the road to a utopia, these science fiction fantasies gave way to traffic jams. The future, it begins to seem, ran out of gas.
Within the Pavilion of the Future, participants will encounter a bewildering array of rooms arranged to form a maze. Each of these rooms will house art installations that are either utopic or dystopic. Utopias are visions of our highest hopes. They paint a picture of a better world. Dystopias are cautionary tales and correspond to fear of what the future has in store. Artists will also be invited to install various kinds of voting devices in the vestibule of the Pavilion. Some of these devices will depend on chance, like slot machines. Others will allow participants to directly express what they immediately feel. All will offer up a stark and simple choice: Will you vote for hope, or will you vote for fear? Further opportunities will be provided by elegant teeter-totters located in the circle that surrounds the Pavilion (a teeter signals green for hope; a totter signals red for fear). Voting booths will also be stationed at locations throughout Black Rock City.
All of these devices will be connected by a closed Wifi network, and linked to a secure computer equipped with a sophisticated software program. This futuristic technology will employ a complex algorithm to determine the statistical mean of our participating community's hopes and fears at any given moment. As a result of these measurements, the Burning Man will either ascend while slowly raising its arms, as if to welcome all our hopes, or descend into a cage of fear located atop the Pavilion's elevated deck. This latter movement will allow participants who win their way up to the deck to witness Burning Man close up through a chrome metal lattice constructed from the gleaming remnants of discarded auto parts. Will the Man remain mired in fear, or will he rise and stretch his arms against the sky? Amid urgent currents of hope and surging riptides of fear, the result is sure to be unpredictable. As with the rotating of the Man of 2005, this daily drama will occur only during evening hours.
Each of us is an emitter of the future, and hope and fear are both legitimate responses to the great unknown. Confronting fear, instead of fleeing it, requires courage and cool reason. This experience can lead to struggle and to change. Expressing what we hope for can inspire faith that opens up a path where none appeared before. In 2006, as the 21st Century rushes forward, the time has come to ask ourselves: Are we merely along for the ride? We encourage all participants to contribute to some aspect of this year's art theme. Create a theme camp that forecasts the future. Imagine alternative pasts which, branching off from what we know, create alternative realities. Immediately confront your own future or the world's future. Plunge into the time stream (and learn how to swim). If you are doing fire art or planning to install a work of art upon the open playa (whether it's related to our theme or not), please see our Art Guidelines for more information. Any art by anyone is always welcome.


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Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy
Young Soo Jung, Jung Hae Choi, Jong Heun Lee
* Highly Cited Researcher
The grain-boundary resistivity of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia (8YSZ) was determined by impedance spectroscopy using sub-millimeter-scale electrodes. During sintering, a liquid that formed at the top surface of the specimen penetrated into the 8YSZ and induced enhanced grain growth near the surface region. The grain-boundary resistivity of the specimen surface was observed to be 150 times higher than that of the interior. The deterioration of the grain-boundary conductivity was explained in terms of the presence of an intergranular siliceous phase.
Materials Science and Engineering B: Solid-State Materials for Advanced Technology
https://doi.org/10.1016/j.mseb.2003.11.009
CaSiO-dropped 8YSZ
Distribution of siliceous grain-boundary phase
Grain-boundary resistivity
Impedance spectroscopy
10.1016/j.mseb.2003.11.009
Dive into the research topics of 'Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy'. Together they form a unique fingerprint.
Liquid phase sintering Engineering & Materials Science 100%
Yttria stabilized zirconia Engineering & Materials Science 89%
liquid phase sintering Physics & Astronomy 84%
Spectroscopy Engineering & Materials Science 74%
yttria-stabilized zirconia Physics & Astronomy 72%
Grain Boundary Chemical Compounds 69%
Sintering Chemical Compounds 55%
Jung, Y. S., Choi, J. H., & Lee, J. H. (2004). Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy. Materials Science and Engineering B: Solid-State Materials for Advanced Technology, 108(3), 219-222. https://doi.org/10.1016/j.mseb.2003.11.009
Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy. / Jung, Young Soo; Choi, Jung Hae; Lee, Jong Heun.
In: Materials Science and Engineering B: Solid-State Materials for Advanced Technology, Vol. 108, No. 3, 15.05.2004, p. 219-222.
Jung, YS, Choi, JH & Lee, JH 2004, 'Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy', Materials Science and Engineering B: Solid-State Materials for Advanced Technology, vol. 108, no. 3, pp. 219-222. https://doi.org/10.1016/j.mseb.2003.11.009
Jung YS, Choi JH, Lee JH. Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy. Materials Science and Engineering B: Solid-State Materials for Advanced Technology. 2004 May 15;108(3):219-222. https://doi.org/10.1016/j.mseb.2003.11.009
Jung, Young Soo ; Choi, Jung Hae ; Lee, Jong Heun. / Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy. In: Materials Science and Engineering B: Solid-State Materials for Advanced Technology. 2004 ; Vol. 108, No. 3. pp. 219-222.
@article{c0146c5be4834b81a5bb5384eaf8d1bf,
title = "Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy",
abstract = "The grain-boundary resistivity of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia (8YSZ) was determined by impedance spectroscopy using sub-millimeter-scale electrodes. During sintering, a liquid that formed at the top surface of the specimen penetrated into the 8YSZ and induced enhanced grain growth near the surface region. The grain-boundary resistivity of the specimen surface was observed to be 150 times higher than that of the interior. The deterioration of the grain-boundary conductivity was explained in terms of the presence of an intergranular siliceous phase.",
keywords = "CaSiO-dropped 8YSZ, Distribution of siliceous grain-boundary phase, Grain-boundary resistivity, Impedance spectroscopy, Sintering",
author = "Jung, {Young Soo} and Choi, {Jung Hae} and Lee, {Jong Heun}",
note = "Funding Information: The work is supported by the Creative Research Initiatives of the Korean Ministry of Science and Technology. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",
doi = "10.1016/j.mseb.2003.11.009",
journal = "Materials Science and Engineering B: Solid-State Materials for Advanced Technology",
T1 - Penetration and characteristics of an intergranular-liquid phase during sintering of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia estimation by impedance spectroscopy
AU - Jung, Young Soo
AU - Choi, Jung Hae
AU - Lee, Jong Heun
N1 - Funding Information: The work is supported by the Creative Research Initiatives of the Korean Ministry of Science and Technology. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.
N2 - The grain-boundary resistivity of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia (8YSZ) was determined by impedance spectroscopy using sub-millimeter-scale electrodes. During sintering, a liquid that formed at the top surface of the specimen penetrated into the 8YSZ and induced enhanced grain growth near the surface region. The grain-boundary resistivity of the specimen surface was observed to be 150 times higher than that of the interior. The deterioration of the grain-boundary conductivity was explained in terms of the presence of an intergranular siliceous phase.
AB - The grain-boundary resistivity of CaSi2O5-dropped 8 mol%-yttria-stabilized zirconia (8YSZ) was determined by impedance spectroscopy using sub-millimeter-scale electrodes. During sintering, a liquid that formed at the top surface of the specimen penetrated into the 8YSZ and induced enhanced grain growth near the surface region. The grain-boundary resistivity of the specimen surface was observed to be 150 times higher than that of the interior. The deterioration of the grain-boundary conductivity was explained in terms of the presence of an intergranular siliceous phase.
KW - CaSiO-dropped 8YSZ
KW - Distribution of siliceous grain-boundary phase
KW - Grain-boundary resistivity
KW - Impedance spectroscopy
KW - Sintering
U2 - 10.1016/j.mseb.2003.11.009
DO - 10.1016/j.mseb.2003.11.009
JO - Materials Science and Engineering B: Solid-State Materials for Advanced Technology
JF - Materials Science and Engineering B: Solid-State Materials for Advanced Technology


text:
>Home >Reading Together >FAQs >How schools can better support effective parenting in their communities
How schools can better support effective parenting in their communities
In 2015, Adam Rivett (Principal of Waimate Main School) wrote a Sabbatical Report based on a synthesis of school visits, interviews and professional reading looking at how schools can support effective parenting in their communities leading to children having better learning experiences at school.
The Sabbatical Report is available for download in PDF, and addresses the following questions:
What does research tell us about the impact of out of school factors on children's academic performance in school?
What is the latest brain development research on the development of the brain in the first 5 years of life and what can primary schools do about this?
What are schools doing to support parents to be more effective in the first 3-5 years of a child's life and what difference (if any) is this having on student academic performance within school?
Where schools and other social agencies are involved together to support parents, how are they making these partnerships with parents sustainable in the longer term?
What are the parents, who are being supported by schools and other social agencies, saying about what affect these school and community partnerships are having for them?
NOTE: In 2016, Adam Rivett wrote a letter to NZEI (NZ's largest education union) and extracts from that letter follow:
Our school has used Reading Together® for about 4 years now and we are also part of the Early Reading Together® programme too through our involvement with the Parenting Hub, which was set up on school grounds to support parenting in our community.
My research clearly shows that parents have an immense impact on the educational outcomes of their children. Some NZ research I looked at, suggested that this impact could be as high as 65% of student outcomes attributed directly to parenting. One English author I looked at suggested out of school factors could account for almost 80% of how well a child does at school.
To be part of this [Reading Together®] programme has been such an honour. It is a brilliant programme and parents find it very, very helpful. At our school, our Reading National Standards are the highest of the three core subjects and I am convinced that our participation in Reading Together® has a large part to play in this.
It seems to me that after 10 years of being a Principal, the biggest problem facing our education system is not what schools are or aren't doing, but really what parents are or aren't doing. The number of ill prepared children entering our schools is just astounding. I see now that the education of parents is just as important, if not more important than the education of their children.
To this end, Reading Together® and Early Reading Together® are two outstanding tools in our toolbox to do this.
AdamRivett_SabbaticalReport2015v1_0.pdf (Size: 492.71 KB)


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text:
PRE-TEENS AND TEENS
Pre-teens and Teens, Preschooler, Uncategorized
Brands of Multicultural Toys That Children Will Enjoy
Posted on March 28, 2022 November 25, 2022 by Miaosmith
Children appreciate toys that mirror their appearance. Here are six companies or brands that offers multicultural toys that cater to a wide range of ethnicities, all of which youngsters will enjoy using.
These six brands of multicultural toys and businesses break down cultural barriers and foster a collaborative learning environment that children will enjoy.
1. Modi Toys
*Image source: www.moditoys.com
It was only after they saw that the market was lacking in South Asian products that Viral and Avani Modi Sarkar were inspired to create Modi Toys, a brand that symbolizes their background and roots.
Plush Hindu deities, including Baby Ganesh and Hanuman, play Hindu devotional chants when squeezed into the Modi Toys collection, unveiled in 2018 and featuring plush toys in their likeness. Companion board books by Modi Toys depict popular Hindu myths and legends.
*Image source: www.bbc.com
The co-founders want to pass on aspects of the Hindu faith and introduce children to these toys from a young age to pique their interest in the culture of the future. You may get these items shipped to over 36 different countries.
2. Bright Bandar Co.
Dhvani Shah's Bright Bandar Co. (translated as bright "monkey" from Hindi and Urdu) encourages bilingualism by educating youngsters to converse in their home tongue.
*Image source: Bright Bandar Co.
My First Words board books in six South Asian languages—Bengali, Gujarati, Hindi, Punjabi, Telugu, and Urdu—are part of the brand's collection (with more languages to come). One hundred native words and their English translations are included in these books.
Children can use this to bond with their grandparents, participate in family discussions, learn about customs, and appreciate cultural jokes and nuances.
3. Kulture Khazana
*Image source: Kulture Khazana
At Kulture Khazana, Akruti Babaria wants to connect families with cultural stories through accessible and cheap books, puzzles, kits, and films. "Khazana" means treasure in Hindi and Urdu.
This product line attempts to foster an appreciation for cultural differences among youngsters by teaching them about festivals, mythology, and more. For example, the Indian rangoli, a popular patterned design used as seasonal decor, is transformed into a kid-friendly puzzle by the firm. Also due in the summer of 2021 are more puzzles, sticker sets, and coloring books.
4. Worldwide Buddies
*Image source: Worldwide Buddies
As a result of moving abroad, founders Evi Triantafyllides and Nefeli Malekou set out to build a platform through which children may have a more accurate understanding of the world and an appreciation for multiculturalism.
Worldwide Buddies is an educational firm that creates multicultural picture books and toys.
There are a variety of gift bundles in the collection, such as the "China Gift Bundle" and "Mexico Gift Bundle," which include a picture book, a plush animal, and multilingual cards. The Book of Cultures, a new 120-page picture book from the company, with 30 tales showcasing multicultural people from worldwide.
5. Little Global Citizens
*Image source: wellingtonworldtravels.com
Akeelah Kuraishi and Tim Minnick have developed a subscription service for children aged 4 to 10 called Little Global Citizens. She wanted to design a product that would show the diversity of cultures she encountered while traveling across 19 nations.
Little Global Citizens lets you see the world from the comfort of your living room. Currently, it has boxes for India, Kenya, Thailand, China, Egypt, Peru, England, and Jamaica, among other countries.
To provide the most authentic experience possible, local experts designed each box from the location in question. The goal is to invest in children a sense of tolerance and respect for people from different backgrounds.
Storybooks, cultural activities, hands-on crafts, language skills, and cuisine help bring each country to life.
6. Ish Dolls
*Image source: toybook.com
Amanda Ealla, who resides in New York, wanted to find a new approach to assist her children in connecting to their ethnic identity and include religion in their daily lives without being overpowering.
In May 2020, she debuted Ish Dolls with a baby Krishna plush doll. To better serve her broad clientele, she immediately recognized that she needed to increase the variety of playrooms she offered.
Ish Dolls aims to bridge the gap between culture and play with T-shirts and onesies.
This entry was posted in Pre-teens and Teens, Preschooler, Uncategorized and tagged Pre-School, Primary, Toddler.
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Copyright 2023 © Parents and Kids Blog. All rights Reserved.


Specificity/Sensitivity: Negative on all human cells and cell lines tested. This antibody recognises a rat cell surface marker, and therefore cannot be used as a negative control in this species. Test results have shown that it is also suitable for use as a negative control with bovine, ovine, porcine, equine, canine, lapine and guinea-pig tissues.
Specificity/Sensitivity: This antibody is suitable for use as a negative control to assess non-specific binding of mouse IgG1 antibodies to target cells. And It is not suitable for use as a negative control on human.


text:
Q: Django CMS - check if placeholder is empty I use:

*

*DjangoCMS 2.4

*Django 1.5.1

*Python 2.7.3

I would like to check if my placeholder is empty.

    {% placeholder "my_placeholder" or %}
    {% endplaceholder %}

I don't want the html between the placeholder to be created if the placeholder is empty.
{% if placeholder "my_placeholder" %}

    {% placeholder "my_placeholder" or %}
    {% endplaceholder %}

{% endif %}

A: If you want additional content to be displayed in case the placeholder is empty, use the or argument and an additional {% endplaceholder %} closing tag. Everything between {% placeholder "..." or %} and {% endplaceholder %} is rendered in the event that the placeholder has no plugins or the plugins do not generate any output.
Example:
{% placeholder "content" or %}

There is no content.

{% endplaceholder %}

A: Here's a very compact solution.
Template filter:
@register.filter('placeholder_is_empty')
def placeholder_is_empty(request, slot):
    page = request.current_page
    placeholder = page.placeholders.get(slot=slot)
    return placeholder.cmsplugin_set.exists()

Usage in template:
{% if request|placeholder_is_empty:'myplaceholder' %}

Here comes some content...

{% endif %}

A: Depending on what you are trying to achieve, you can simply use CSS to hide the element if doesn't have content using the :empty selector. And if you are worried about white spaces you can use Django's in-build {% spaceless %} template tag to remove them.
So you'd get this template:
{% spaceless %}

    {% placeholder "my_placeholder" %}

{% endspaceless %}

And this CSS:
hide_if_empty:empty {
    display: none;
}

Not exactly what was asked for as it doesn't remove the HTML - but this will solve the most common case where one wants to check if a place holder is empty, and doesn't require the introduction of a new template tag.

A: There is no built-in way to do this at the moment in django-cms, so you have to write a custom template tag. There are some old discussions about this on the django-cms Google Group:

*

*https://groups.google.com/forum/#!topic/django-cms/WDUjIpSc23c/discussion

*https://groups.google.com/forum/#!msg/django-cms/iAuZmft5JNw/yPl8NwOtQW4J

*https://groups.google.com/forum/?fromgroups=#!topic/django-cms/QeTlmxQnn3E

*https://groups.google.com/forum/#!topic/django-cms/2mWvEpTH0ns/discussion
Based on the code in the first discussion, I've put together the following Gist:

*

*https://gist.github.com/timmyomahony/5796677
I use it like so:
{% load extra_cms_tags %}
{% get_placeholder "My Placeholder" as my_placeholder %}

{% if my_placeholder %}

    {{ my_placeholder }}

{% endif %}

A: Based on the great answer form @Philip Zedler, a solution that works for both placeholder on django-cms pages, but also on placeholders "outside of the cms".
@register.filter()
def placeholder_empty(page_placeholder, slot=None):
    """
    for page/slot, pass a page object, and a slot name:
    {% if request.current_page|djangocms_misc_placeholder_empty:"content" %}

    for a outside page placeholder, just the placeholder object:
    {% if object.placeholderfield|djangocms_misc_placeholder_empty %}

    also, with:
    {% with ph_empty=object.placeholderfield|djangocms_misc_placeholder_empty %}
    """
    placeholder = None
    if isinstance(page_placeholder, Placeholder):
        placeholder = page_placeholder
    elif isinstance(page_placeholder, Page):
        page = page_placeholder
        try:
            placeholder = page.placeholders.get(slot=slot)
        except Placeholder.DoesNotExist:
            pass
    if placeholder:
        # // return not placeholder.cmsplugin_set.filter(language=get_language()).exists()
        return not placeholder.cmsplugin_set.exists()
    return False

usage in template
{% if request.current_page|placeholder_empty:'content' %}

Fallback!

{% endif %}

It's in my djangocms-misc package

A: I took the extra compact solution here and created a templatetag that checks if a static placeholder is not empty:
from cms.toolbar.utils import get_toolbar_from_request

@register.filter("static_placeholder_is_not_empty")
def static_placeholder_is_not_empty(request, slot):

    placeholder = StaticPlaceholder.objects.get(code=slot)

    if get_toolbar_from_request(request).edit_mode_active:
        placeholder = placeholder.draft
    else:
        placeholder = placeholder.public

    is_not_empty = len(placeholder.get_plugins(request.LANGUAGE_CODE)) > 0
    return is_not_empty

It's used like this:
{% load my_new_shiny_templatetag %}

{% if request|static_placeholder_is_not_empty:'my_static_placeholder' %}

{% endif %}

{% static_placeholder "my_static_placeholder" %}

{% if request|static_placeholder_is_not_empty:'my_static_placeholder' %}

{% endif %}

redpajama_set_name: RedPajamaStackExchange


ARE you aged between 12 – 24 and are passionate about the environment?
Do you want to connect with other young people who feel the same, learn new skills, identify ways to reduce your eco-footprint and make your home and school more sustainable?
As part of National Youth Week, Alpine Shire Council is hosting a "Youth Leading the World" Sustainability and Environment Congress on Wednesday, 9 April and Thursday, 10 April.
Youth Development Officer Ebony Buckley said the congress was a fantastic way for young people to come together to meet new people and learn how to address issues of concern around climate change, sustainability, food security and the environment.
"We have partnered with sustainability and community-driven change organisation OzGreen to run this congress for two days over the school holidays," she said.
"Trained facilitators will work with participants to gain a better understanding of their eco footprint and identify ways for them to become more sustainable in the homes, schools and communities.
The Congress will run at the Bright Courthouse from 10am – 5pm on Wednesday, 9 April and Thursday, 10 April.
Bookings are essential. Anyone aged between 12 – 24 is welcome to attend.
This is a free event. Morning and afternoon tea and lunch will be catered.
For more information or to book contact Ebony Buckley on (03) 5755 0506 or ydo@alpineshire.vic.gov.au by Monday, 7 April.


It took a while, but they finally decided to introduce a plot to our story. So it comes down to a war between the wolves to gain more territory. I just find it odd they separated it by west and east, it seems to be a bit random to split things like that. At least this insures an huge upcoming brawl, not like their hasn't been action every episode.
So we get a slight intro to our super bad luck loli. I was hoping she would get some more screen time. To find out what her role was. Still, she does not replace Ume, I was so sad to realize she got zero screen time this episode. I still think getting a billion free cans of coke isn't bad luck. The powers of her bad luck are pretty awesome nonetheless. I am wondering what would happened with our loli and Ume if they were put together.
The bulk of the episode being the introduction to Monarch. I was surprised that a rivalry exists. Wolves are suppose to hunt solo. For them to band together to fight as a side feels awkward. I mean, The best of a location fighting another best should have no real correlation. It is just a battle between two of the best wolves and has zero repercussions to any of the other wolves. It just seemed very awkward to have a war between the two sides.
It is pretty obvious she was one of the two wolves that battled it out to start the rivalry. She is even introduced as one of the retired wolves. They didn't even attempt to hide it. I can only assume she will get more screen time to start a flashback of what has happened in the past in the midst of the brawl. I think it is a bit early still to be introducing this as the major climax and I would be pretty disappointing if it got dragged out too badly.
Still an extremely entertaining show with an introduction of a more solid plot. As long as they keep their wacky humour with some crazy brawls, it is fine by me. I guess the fighting being so simple is just the break I need. When anime all need super special finishing moves to keep things flashy, a simple punching brawl stands out amongst all those battle anime. Definitely an anime I am enjoying quite a bit.


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div[data-listview] table th {
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div[data-listview] .item {
    border: 1px solid white;
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div[data-listview] .item:hover {
    background-color: #EFF7FF;
    border: 1px solid #9CB9F7;
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div[data-listview] .item .thumb img {
  width: 30px;
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div[data-listview] .item .thumb {
  position: relative;
  border: 1px solid gray;
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  border-radius: 3px;
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div[data-listview] .column-title {
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redpajama_set_name: RedPajamaGithub


According to a release from the Nacogdoches County Sheriff's Office (NCSO), on Thursday afternoon, July 13th, the NCSO conducted a search warrant at a residence on Pecan Street.
Found at the residence was the primary suspect in the investigation, James Johnson (top middle photo). Investigators conducted a search of the residence that resulted in the seizure of ½ pound of marijuana and drug paraphernalia. Johnson, 62, from Nacogdoches was transported to the Nacogdoches County Jail and booked in on Possession of Marijuana, a state jail felony.
On Friday July 14th, the NCSO and the Nacogdoches Police Department conducted a joint investigation. Both agencies executed a search warrant on a residence located on Hollywood Street in Nacogdoches. Jose Eduardo Roque, 46, (top right photo) was the primary suspect in the ongoing investigation. Officers from both agencies conducted a search of the residence which led to the discovery of methamphetamine, marijuana and two handguns. Roque was charged with Delivery of Controlled Substance, felony 2nd degree, unlawful possession of a firearm by felon , 3rd degree felony and misdemeanor possession of marijuana. Roque was transported and booked into the Nacogdoches County Jail.
On July 17th, around 1:00 am, deputies conducted a traffic stop on a Nissan passenger vehicle for a traffic violation on highway 59 North. The driver and lone occupant of the vehicle was identified as Halston Lewis, 25, from Hurst, Illinois. Lewis was very nervous while speaking with deputies and gave conflicting statements about his trip. Deputies received consent to search the vehicle. The search led to the seizure of 10.4 lbs. of marijuana concealed in the trunk of the vehicle. Lewis was arrested for Possession of Marijuana and transported to the Nacogdoches County Jail. His bond was set at $25,000.00 dollars.
On July 18th, around 2:00 am, deputies stopped a grey Honda civic for a traffic violation in the 2500 block of South Street. There were five occupants inside the vehicle that were all later arrested. All subjects were very nervous and deputies suspected criminal activity due to their behavior. Deputies obtained consent to search the motor vehicle. During the search deputies discovered 1.4 pounds of marijuana, and 35.1 grams of THC wax .
Kelvin Scott, 22(bottom left photo), Wael Laarits,19 (bottom middle photo), Domineek Mojica,19 (bottom right photo), Abril Morales, 20 (top left photo), all from Nacogdoches and Jeffery Davis, 20, from San Antonio were all arrested for Possession of Controlled Substance a 2nd felony and Possession of marijuana a state jail felony.


PISTÓN F, GIL-HUMANES J, RODRÍGUEZ-QUIJANO M, BARRO F (2011). Down-Regulating γ-Gliadins in Bread Wheat Leads to Non-Specific Increases in Other Gluten Proteins and Has No Major Effect on Dough Gluten Strength. PLoS ONE 6(9): e24754. doi:10.1371/journal.pone.0024754.
RUIZ M, AGUIRIANO E, GIRALDO P, CARRILLO JM (2011). Genetic redundancy among durum wheat accessions as assessed with SSRs and endosperm proteins. Spanish Journal of Agricultural Research 9:156-165.
MOLNÁR I, CIFUENTES M, SCHNEIDER A, BENAVENTE E, MOLNÁR-LÁNG M (2011). Association between simple sequence repeat-rich chromosome regions and intergenomic translocation breakpoints in natural populations of allopolyploid wild wheats. Annals of Botany 107, 65-76.
SIN E, DELMORAL J, HERNÁNDEZ P, BENAVENTE E, RUBIO M, MARTÍN-SÁNCHEZ JA, PÉREZ RF, LÓPEZ-BRAÑA I, DELIBES A (2011) Effects of the 4N(v) chromosome from Aegilops ventricosa on agronomic and quality traits in bread wheat. Czech J. Genet. Plant Breed., 47 (Special Issue): S63–S66.


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Cross-country runners at the 2018 Heartland Classic pushed past more than just their competitors on Saturday; the 98-degree heat index forced many athletes past their point of endurance.
At least five athletes in the varsity boys race alone were taken to the emergency room after their race, and the meet saw at least 15 others faint from the heat. Kelly-Harvey was competing in her first ever varsity race, and was positioned fifth on the team when she dropped out.
"I'm over it. I didn't finish and I can't take it back, so I'm just looking forward to next week," Kelly-Harvey said.
In an unprecedented season in which four of the six scheduled meets so far have been canceled, many athletes are itching to compete.
"It's really frustrating not being able to race, just because it's our senior year and everyone wants to improve and enjoy the meet one last time," Ella Hennager '19 said.
For seniors, the cancellation of meets means not being able to revisit courses at which they have spent years racing.
The Heartland Classic was the first meet of the season for most runners, so frustration was high when less than ideal racing conditions did not allow for a satisfactory first race. Despite this, runners found a way to look on the bright side.
Hassan's positive attitude towards the race was one shared by many of the other students on the teams.
The varsity girls placed 12th in a field of 30 other teams, with the JV girls finishing third overall. Varsity boys placed 23rd, and JV left with a 10th place finish. The girls team is looking to improve their spot in the rankings.
"I think at the varsity level once we put the pieces together and get everyone feeling good on the right day, we're going to move on up the rankings even further," Ryan Ahlers, co-head coach, said.
Leading the varsity is freshman Rowan Boulter, who broke the record for the fastest time in City High history in her very first 5K race at time trials.
Boulter admits to being a little intimidated coming into the sport as a freshman athlete, but said that the team environment has made up for it.
The boys are also experiencing a number of freshmen and sophomore athletes making their mark on varsity. Freshmen Parker Max, Sullivan Hall, and Elliot Dunwald have each been racing at a varsity level this season.
With only four opportunities to compete left in the season for most runners, the coaches are excited to see what they can push themselves through.


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East Bracklesham Drive, Bracklesham Bay, PO20
Detached Bungalow Close to Beach
Large Corner Plot
Separate Cloakroom/WC
Parking + Garage
Re-development Potential in Garden
No Forward Chain
A detached bungalow, now in need of refurbishment, located not far from the beach on a large, corner plot that has a second garden area with potential for re-development (subject to the usual consents). There is no forward chain.
Internally, the accommodation measures 1,146 sq ft and briefly comprises: entrance porch with door to lobby area which, in turn, has a door to the kitchen/breakfast room which has some fitted units, a good sized dining area and door to the side of the property. Also from the lobby is a door leading to the spacious sitting room with its window overlooking the front garden, tiled mantelpiece and door to the inner hallway. From here is a double store cupboard and doors to all three bedrooms, the bathroom and a separate cloakroom/WC. EPC-D
The property sits on a large corner plot with two areas of garden to the rear separated by a wrought iron gate - one of which may have the potential for re-development, subject to the usual Planning consents. The gardens are laid mainly to lawn with a variety of trees and shrubs, pathways, patio area and wooden shed. The front of the property is approached by a low wooden gate opening into the driveway which provides parking and access to the single attached garage; it also has an area of lawn with numerous trees, shrubs and flowers. The garage has a personal door leading to the rear of the bungalow and also has two separate, adjacent storage cupboards accessed from outside.
Situated at Bracklesham Bay, a coastal village some 7 miles south-west of the City of Chichester. The beach there is a popular place to enjoy a variety of water sports or admire the lovely view towards the Isle of Wight. 'Billy's' beachside café/restaurant and some local shops are close by, although further amenities can be found at the nearby village of East Wittering, including: infants/junior school, GP surgery, chemist, dentist, library and a range of quality independent shops. There is a regular bus service to Chichester City centre with its range of shops, restaurants, cinemas, Festival Theatre and main line railway station. Goodwood Racecourse and Motor Circuit are some 3 miles beyond Chichester.
A detached bungalow, now in need of modernisation, on a large corner plot located close to the beach
Sitting Room 16' (4.88m) x 10'8 (3.25m)
Kitchen/Dining Room 11'8 (3.56m) x 7' (2.13m)
Breakfast Room 12'5 (3.78m) x 9' (2.74m)
Bedroom 1 11'9 (3.58m) x 11'5 (3.48m)
Bedroom 2 17'1 (5.21m) x 7'4 (2.24m)
Bedroom 3 9'8 (2.95m) x 9' (2.74m)
Large Garden on Corner Plot
Garage 17'8 (5.38m) x 9'8 (2.95m)
Details correct: BG/CE 21/06/2019
Why live in the Witterings?
People flock to East Wittering during the holiday season thanks to our world-famous beaches that are so beautiful and a way of life that's relaxed and warm.
It's little wonder we experienced significant building development during the 1960s and '80s when our rich mix of character house styles in the Witterings made it hard for people to leave. Many of the properties in the area enjoy wonderful views across the English Channel and the sound of distant waves provides a soothing backing track to everyday life here.
There's no shortage of things to do in the area, especially if you enjoy spending time on the beach, playing water sports and experiencing the countryside and wildlife. Both East and West Wittering are well known for sailing and surfing and there are local sailing clubs at West Wittering, Itchenor and Dell Quay and mooring facilities at Chichester Marina. West Wittering beach is postcard-perfect with its vast expanses of fine golden sand while East Wittering is more typically English with a shingle shelf that's exposed when the tide goes out leaving behind stunning areas of wet sand where you can make sandcastles to your heart's content. The nearby Bracklesham Bay is especially popular with surfers, divers, windsurfers and paddle boarders as well as being a treasure trove for fossil hunters.
We have everything here you need to enjoy this idyllic lifestyle here. In the village you'll find a good selection of shops, including mini supermarkets, greengrocers, butchers, banks, bakers and a fishmonger and everything is close by in Chichester and Portsmouth. We have two local schools for children up to 11 years of age at East Wittering Community Primary School and West Wittering Parochial C of E School and a choice of secondary schools and further education options in Chichester.
If you'd like to buy, sell or let a property in East Wittering, get in touch with your local team and discover the Henry Adams difference for yourself.
Owers Way, West Wittering, PO20
Detached CHALET BUNGALOW with light, spacious accommodation, set within sought-after CUL-DE-SAC close to village centre. 2 Shower Rooms + en suite cloakroom. Garage...
5 Field Road, East Wittering, PO20
Offers In Excess Of £550,000 (Freehold)
Detached chalet-style house in QUIET, CUL-DE-SAC LOCATION in seaside village, not far from village centre and amenities.
Bracklesham Lane, Bracklesham Bay, PO20
A handsome and SPACIOUS family home in village outskirts. 1,517 sq ft of FLEXABLE ACCOMODATION, generous private grounds of 0.44 acre and NO FORWARD CHAIN.
A detached chalet bungalow CLOSE TO THE BEACH, in need of complete REFURBISHMENT with LARGE GARDEN on TOTAL PLOT of 202' x 50'.


Have YOU Been Charging Your Phone Correctly?
You don't usually think much about batteries… until your phone, tablet or laptop dies. Most people fear running out of power when they're out and about. When our battery is down to about 50%, our instinct is to immediately charge it all the way up. Many of us charge our phones several times a day, despite the potential of damaging our batteries. The average lifespan for phone batteries is three to five years. How do we properly charge it to keep our batteries alive as long as possible?
Batteries do not enjoy eternal life. Most smartphone manufacturers say their devices' batteries are rated at 300-500 cycles. Apple claims that its laptop batteries reach 80 percent of their original capacity after 1,000 charges.
The big question about how to recharge a battery is whether you should let it run completely dry before charging back up to 100 percent.
It's better to not fully charge or fully drain your battery. Lithium-ion batteries do not need to be fully charged. In fact, the stress of high voltages can actually wear your battery down and cause to it to die sooner. Similarly, draining your battery completely also ages it by increasing the total number of "cycles" the battery goes through.
There are two stages of battery charging. The first stage, the fast charge period, is when the voltage is higher. It reaches about 70% of capacity during this stage. The second stage, the trickle-charge period, takes much longer, and the remaining battery is slowly charged from 70% to 100%.
Lithium-ion batteries cannot absorb overcharge. Once fully charged, the charge current must be cut off, but, not to worry, the charger will do that automatically.
Avoid extreme heat and cold. Operating temperatures are between between 32 and 95 degrees Fahrenheit. You can keep your phone out of direct sunlight and take it out of its case while charging to avoid damage to the battery.
Q: At what percentage should I charge my phone?
A: A good range to aim for when charging a Li-ion battery is from about 40-80 percent. Try not to let the battery drop below 20 percent.
Q: When should I do a full battery charge?
A: Experts recommend that you do a full zero to 100 percent battery recharge (a "charge cycle") maybe once a month only. This recalibrates the battery - a bit like restarting your computer, or, for people, going on holiday!
Q: Should I charge my phone overnight?
A: Most modern smartphones are clever enough to stop charging when full, so there isn't a great risk in leaving your phone charging overnight.
Q: Should I use fast charging?
A: Many Android phones have a feature that allows for fast charging, often referred to as Qualcomm Quick Charge or, in Samsung's case, Adaptive Fast Charging - there are others. The iPhone 6 doesn't feature fast charging, but its Qualcomm PMIC is smart enough to recognise when you use a higher-amp charger (like the one you get with the iPad), and that's a good thing because fast charging will heat up that Li-ion battery and cause increased wear.
Q:What is the battery memory effect?
The battery memory effect refers to NiCad "forgetting" portions of its capacity due to consistently remaining under or over a certain charge level. Lithium-ion (Li-ion) batteries don't suffer the memory effect so you almost need to do the opposite: charge them often but not all the way throughout the day, and don't let them drop to zero.
Don't leave a Li-ion battery li-ing around too long at 0 percent. Try to leave it at around 40-50 percent.
These batteries drain at about 5-10 percent a month when not in use. If you let the battery discharge completely and leave it uncharged for a long period of time it may eventually become incapable of holding a charge at all (that's properly dead).
It's unlikely you'll leave your smartphone lying in a drawer for very long, but some people do leave their laptops, battery packs or spare batteries unused for long periods of time. So try to keep them all at least half charged.
and that's a good thing because fast charging will heat up that Li-ion battery and cause increased wear.
I'm not sure if increased wear is a good thing though.
Great article to sum up FAQ.
Q: Should I charge my phone overnight?A: Most modern smartphones are clever enough to stop charging when full, so there isn't a great risk in leaving your phone charging overnight.
I remember "back in the day" my family had an old VHS-style video camera with a NiCad battery. We had to always discharge the battery all the way before charging the battery again because of the "memory effect". And you couldn't interrupt the charge until it was at 100% again or that would mess it up, too. It was a huge pain to plan around. I'm glad modern batteries are so much more user friendly!
Thank you for sharing this with us Anker and making are batteries safer and do's and don'ts on how to charge our batteries.
Thank you for the great source of info.
I woke up this morning, logged on to my Anker account as I always do, and was so excited to see this post! Don't know why I'm only now seeing it, but nonethless, this sort of thing is exactly the type of info I was asking for in my thread titled "Cleaning/Maintaining/Servicing Anker Products." Of course, my phone isn't manufactured by Anker, but it's still extremely relevant to Anker being that phone accessories are what initially introduced me to the Anker brand, and thus, the Anker community.
it's not really serviceable I think, so the best you can do is wipe with dam tower then wipe dry. for the cable, I think there's some cleaning cream which used for shoe can be used here as well.
I always charging my phone overnight!
Thanks, more hidden knowledge will be revealed and shared.
Thanks you for sharing this link with us, it's really insightful!
Thanks for the great write up. I typically follow these rules for charging our families' mobile devices. I find that following these basic steps our device's batteries last a little longer than our friends that have the same devices.
Cool! I'm very happy to share the useful charging tips with you!


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Home / Baseball / What to Watch For Wednesday: Former Noles Continue Summer League Action, Football Watch Lists
What to Watch For Wednesday: Former Noles Continue Summer League Action, Football Watch Lists
Steve Musco/FSU athletics
More than a month separates us from the new athletic year for Florida State, but some former Seminoles will continue their auditions for their professional teams and preseason prognostications will soon ramp up.
SUMMER LEAGUE RESUMES
Five former FSU basketball players have participated in the NBA Summer League out in Las Vegas. That wraps up on Monday with the final. Consolation games begin on Friday and quarterfinals get underway on Saturday.
Impressing the Los Angeles Clippers so far have been rookies Mfiondu Kabengele and Terance Mann. Kabengele leads the Clippers through three Summer League games in scoring at 17.7 points per game while shooting 46 percent from the field to go with a team-high two blocks. Kabengele started Summer League action with 21 points and 10 rebounds in a win over the crosstown Los Angeles Lakers.
Mann is averaging just below nine points per game in three Summer League contests, but leads the team with 11.7 rebounds and 5.7 assists per contest. In a win over the Washington Wizards on Tuesday night, Mann narrowly missed a triple-double with 15 points, 11 rebounds and nine assists.
So far in Summer League action, the Clippers are 2-1. They'll face the Sacramento Kings on Thursday night.
The other FSU rookie participating in Summer League action is 7-foot-4 center Christ Koumadje with the Philadelphia 76ers and thus far, he has impressed. Koumadje is averaging seven points, six rebounds and three blocks in three Summer League contests while shooting 69 percent from the field.
After finishing with 11 points, seven rebounds and five blocks in a win over the Milwaukee Bucks in his first Summer League contest, Koumadje followed up a scoreless performance with 10 points, 11 rebounds and four blocks in a loss to the Oklahoma City Thunder on Monday. Philadelphia is 1-2 in the Summer League and will face the Detroit Pistons on Wednesday afternoon.
Guard Dwayne Bacon has averaged a team-high 19.5 points per contest in two Summer League games for the Charlotte Hornets. Bacon followed up a 25-point performance in a win over the Golden State Warriors with 14 points in a loss to the San Antonio Spurs. At 1-2, the Hornets will face the Chicago Bulls on Wednesday evening.
In two Summer League games for the Orlando Magic, Braian Angola has averaged seven points and two assists. Angola finished with seven points and two assists in both a win over the San Antonio Spurs and a loss to the Denver Nuggets. The Magic are 1-2 in the Summer League and will face the Brooklyn Nets on Wednesday evening.
Beginning Monday, college football will begin releasing its preseason watch lists. Over two work weeks, 16 different watch lists will be unveiled.
Here is the 2019 Preseason Watch List Calendar … 16 lists over 10 weekdays from July 15-26. pic.twitter.com/bVY0EE3weT
— NCFAA (@ncfaa) May 16, 2019
Names that could appear on various lists for Florida State include Cam Akers, Tamorrion Terry, Tre' McKitty, Marvin Wilson, Levonta Taylor, Jaiden Lars-Woodbey, Dontavious Jackson, Ricky Aguayo and Logan Tyler. FSU hasn't had a player win a major national award since Nick O'Leary took home the John Mackey Award as the nation's best tight end in 2014.
When it comes to lesser awards, running back Dalvin Cook won the Jim Brown Award in 2015. In 2016, cornerback Tarvarus McFadden took home the Jack Tatum Award.
Mike Ferguson is the editor of The Daily Nole. Follow Mike on Twitter @MikeWFerguson. Like The Daily Nole on Facebook. To pitch an idea, author a post or to learn more about The Daily Nole, email Mike Ferguson at Mike@TheDailyNole.com.
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Webster County falls to Henry Clay 5-1
Webster County dropped a 5-1 decision to Lexington Henry Clay Monday in its opening game at the Cocoa Expo in Cocoa Beach, Florida.
Webster County falls to Henry Clay 5-1 Webster County dropped a 5-1 decision to Lexington Henry Clay Monday in its opening game at the Cocoa Expo in Cocoa Beach, Florida. Check out this story on thegleaner.com: http://www.thegleaner.com/story/sports/2018/04/02/webster-county-falls-henry-clay-5-1/480508002/
, The Gleaner Published 9:13 p.m. CT April 2, 2018
A bucket of baseballs sits on the field during game between the Southern Indiana Shockers and the McCutchanville Mud Dogs on the Mickey Martin baseball field at McCutchanville Community Park in Evansville, Thursday, Oct. 13, 2016. The Mickey Martin baseball field could be in jeopardy as the Evansville Vanderburgh School Corp. finalizes plans for a new North Side elementary school.(Photo: Alex Slitz / Courier & Press)Buy Photo
COCOA BEACH, Florida -- Webster County dropped a 5-1 decision to Lexington Henry Clay Monday in its opening game at the Cocoa Expo in Cocoa Beach, Florida.
Henry Clay pitcher Kennedy Parks limited the Trojans (0-3) to three hits. Webster County scored its only run in the top of the first when Gabriel Salazar walked and scored with the help of two Henry Clay errors.
The Blue Devils (5-1) had five hits against Webster County pitchers Logan Erickson and Luke May. Louis Kessinger was 2-for-4 and Proctor Mercer drove in three runs with two coming on a home run in the third inning.
Webster County is scheduled to face Cross Lanes Christian, West Virginia Tuesday at 3 p.m.


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Capital gains. Political losses
Jan Tucker
In 1996, the Los Angeles Times called me a "P.R. Guru" and whether it was true or not, the accusation took on a life of its own and people began to believe it. Whatever one believes to be true becomes binding upon them and determines the outcome of their behavior. So since then I've had a decent track record at promoting causes that nobody else would touch or even conceive of as being promotable.
If there's one thing I can't stand it's when a client or an organization that I'm promoting misses an opportunity for publicity when an "I told you so" moment arrives. Although it's been decades since the California Peace & Freedom Party allowed me any official role in public relations, I almost wish that I was on speaking terms with the leadership (of my own party) so that I could nudge them into jumping on an obvious P.R. offensive that could help to convince the public that the party is still relevant. One of its key early issues has all of a sudden become the subject of major national debate and yet the party leadership and its candidates aren't saying anything about it.
Ambrose Bierce once defined that "Radicalism is the conservativism of tomorrow, injected into the affairs of today." In 1971-72, the California Peace & Freedom Party (PFP) launched an initiative petition drive under the leadership of the San Jose Eugene V. Debs PFP Club to tax capital gains at the same rate as ordinary income. At the time this was both a radical and a rational program of tax reform.
The ethical and moral implications of the differential between capital gains taxation — i.e., the tax on profits from stock, real estate, bonds, etc. — as opposed to the income one derives from working for a living is basic fairness. Why should somebody who invests for a living get a tax break while somebody who works for a living does not? The usual answer is that the lower tax rate is justified by the need to encourage investment to produce jobs, a trickle down philosophy.
So, at the risk of criticizing a simplified straw man argument, let me get this straight: if you don't give somebody a tax incentive to invest money they won't invest it? What do you think they're going to do? Get a job?
I was the Los Angeles County coordinator for the PFP initiative to reform the capital gains law in California. I solicited and received endorsements for the proposal from the Los Angeles Democratic Club, UAW Local 645 and a lot of other mainstream organizations that recognized the simple fairness message of the proposal. Still in 1971-72, this was considered a radical notion, that people who earn the same amount of income should be taxed at the same rate regardless of whether they are a worker or a capitalist.
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Steve G
Feb 14, 2012 / 4:16 pm
I'd like to see it taken one step further. I think that investments for companies that have most of it's workforce inside the USA should have the capital gains on those investments still taxed at a lower rate than ordinary income. But only if those companies are based in the USA and actually hire USA workers for most of it's workforce. Investors don't care where the products are made or sold, they only care about the bottom line. So if they were taxed at a higher rate for say investing in Apple, they would look at invest in a USA corporation who hires mostly USA workers and they would be keeping more of the profits they make by enjoying a lower tax rate on that investment. The same monetary investment you could send to a corporation in India and make 20% and be taxed at say 30% wouldn't be as profitable as the same amount of monetary investment you could send to a USA corporation who hires mostly USA workers and still make that 20% profit, but have that investment be taxed at a lower rate. I understand at one time we needed people to invest in corporations and so a lower capital gains tax rate made it attractive to do so, but it's one of the many things on a long list of things that are killing the USA today. We can't keep on with the same policies that were necessary before, but are not necessary today, especially if today they hurt the US and not do much to help it.