Scott Kirsner here… long-time fan of Beet.TV, first-time guest blogger. Like Andy, I've been following the evolution of online video as an incredibly powerful new distribution channel for content, writing in the Boston Globe, Variety, the NY Times, and on my own blog, CinemaTech.
I've spent the past 18 months talking to content creators about how they are navigating this new landscape, where video has suddenly become free to create and distribute. If you're a talented filmmaker, documentarian, animator, or vlogger, how do you actually earn a living in this incredibly noisy environment?
In a book that has just been published, I collect interviews with 30 of the creative innovators who've been trying to answer that question: people like "What the Buck" star Michael Buckley, the animators behind "Homestar Runner" and "Red vs. Blue," and documentarians like Robert Greenwald, who's now working on a project about the war in Afghanistan and releasing parts of it on YouTube before it's complete. The book is called Fans, Friends & Followers: Building an Audience and a Creative Career in the Digital Age.
Two of the people who've been pioneering this new kind of audience-building (and testing new business models) are Gregg and Evan Spiridellis of JibJab Media, founded a decade ago. In particular, they were early in their attempts to make ad-supported content work, and then moving away from advertising toward a subscription-based business model.
about $75,000 to make the videos. Where's the profit, where's the scale?
near-miss instead of a real hit, you're in the red.
so low with e-cards didn't mean it had to stay there.
content, and they share in the revenue that gets generated by that content.
hit some sort of steady model is a false hope. You've just got to keep moving.
got a boss. And with JibJab, we got used to going directly to our audience.
just didn't feel like the right time.
Editor's Note: It is with great pleasure to welcome Scott as a contributor to Beet.TV. He is one of the most astute observers of the digital media world and I am flattered he is contributing here.


text:
China National Gold's President Says No Longer In Talks With Ivanhoe Mines On African Investment
Alistair MacDonald broke the news that China's largest gold company, China National Gold, was no longer in talks with Ivanhoe Mines Ltd, the vehicle of famed mining entrepreneur Robert Freidland, and that it was in talks with Barrick Gold Corp. about potential partnerships. The story came through an exclusive interview with the company's president, who also said he was actively talking to other companies about takeovers.
June 17, 2014, 10:56 AM EDT – China National Gold's President Says No Longer In Talks With Ivanhoe Mines On African Investment
10:56 AM EDT: China National Gold President Says Talking To Barrick Gold About Potential Partnerships
10:56 AM EDT: China National Gold President: Chinese Gold Demand Likely To Be Slightly Lower In 2Q Vs 1Q
11:39 AM EDT: China National Gold Is Talking to Barrick About Potential Partnerships
By Alistair MacDonald
China's largest gold-mining company, China National Gold Group Corp., is on the hunt for global acquisitions and partnerships, the company's president said, in a move would make it a potential kingmaker in the beleaguered gold industry.
Xin Song said that he recently talked about potential partnerships with Barrick Gold Corp., the world's largest gold producer. But he said talks about an investment in the African properties of another well-known mining name, Robert Friedland, aren't currently active.
China is the world's biggest consumer and producer of gold, giving the nation increasing sway when it comes to both its price and production. Last year, the country's gold consumption grew to more than 1,176.4 metric tons, but its production was 428 metric tons, a dynamic which encourages overseas acquisitions, analysts say.
Mr. Song said he believed that demand for gold in China will remain strong even if the second quarter of this year sees a slight decline over the preceding quarter.
Acquisitions by China Gold would revive the mainly moribund market for gold mergers and acquisitions. Despite April's acquisition of Osisko Mining Corp. and several assets sales by gold majors, deals in this sector have fallen as smaller companies struggle to raise finance and larger firms mainly steer clear of acquisitions after years of empire-building.
So far, Chinese companies have mainly been cautious. Mr. Song said that his firm is actively searching the world for opportunities in gold, silver and copper.
"The growing strategy is very clear, we are going out looking at things globally," he told The Wall Street Journal. "On our hands we have a few opportunities, at different stages."
Speaking through an interpreter, Mr. Song said the company's current first preference is for assets in countries that border or are near to China, such as Mongolia, Russia and some of the Central Asian republics. It is also looking for acquisitions in developed countries, such as Canada, Australia and the U.S. As a third option, it is looking at opportunities in developing countries including those in Africa and South America. But "the political situation has to be stable," he said.
The Wall Street Journal reported last September that China Gold had examined buying a stake or operating part of Ivanhoe Mines, which wants to mine copper and zinc in the Democratic Republic of Congo and gold, nickel and copper in South Africa.
Mr. Song said it hasn't held talks recently and, in Africa, is currently focused on its properties in the Republic of Congo. The mining executive said that China Gold has a long relationship with Friedland, who is Ivanhoe's founder and chairman.
"We keep a hotline" open with the entrepreneur, he said. "But we need to figure what the advantage points where we can work together. Just like a marriage we have to know the common benefit."
Last week, Mr. Song talked to John Thornton, the chairman of Barrick Gold, who has set a key priority for his firm of establishing long-term relationships with Chinese partners.
"Both parties are looking for potential opportunities jointly," Mr. Song said. "The possibility is there," he said, though added that the two weren't yet working toward any specific project.
That opportunity, though, is unlikely to include an investment in Pascua Lama, a massive mine on the border of Chile and Argentina that Barrick Gold has put on hold amid cost overruns and environmental demands from the Chilean government. Mr. Song said the project has several challenges, including its high elevation, its permitting troubles and high capital expenditure.
Chinese gold consumption increased by 41% last year as people took advantage of a fall in the price of gold to buy jewelry and gold bars. Growth tailed off in the first quarter of this year as consumers exited gold investments, in what analysts said underscores how an economic slowdown and constrained credit markets are reducing demand in China after a decadelong buying spree.
Mr. Song, who is also the president of the China Gold Association, said that he believed that the second quarter will be "a little bit lower" than the first quarter but long term demand should stay strong, not least as a younger generation buys jewelry online.
"The Chinese gold industry plays a very important role in the global gold industry," he said.
Write to Alistair MacDonald at alistair.macdonald@wsj.com

redpajama_set_name: RedPajamaCommonCrawl


Tool holder (mostly Ender 3 tools) by bantamas is licensed under the Creative Commons - Attribution license.
Honestly, the holes are pretty tight. But, I guess is my printer's faults.
If you scaling it up with 1-2%, its gonna be better.
The material is doesn't matter.
Say thanks by giving bantamas a tip and help them continue to share amazing Things with the Thingiverse community.
We're sure bantamas would love a Tip, but unfortunately they have not setup their accounts to receive them yet.


text:
Nadi al-Muthanna (Al-Muthanna Club) fu un'influente associazione panaraba d'ispirazione fascista con sede a Baghdad. Creata nel 1935, rimase attiva fino al fallimento del colpo di Stato filo-nazista tentato da Rashid Ali al-Kaylani nel 1941. L'associazione prese il nome da Al-Muthanna ibn Haritha, antico guerriero e capo tribale musulmano protagonista della Battaglia di al-Qadisiyya. Il gruppo, successivamente rinominato "Partito Nazional Democratico", fu fortemente influenzato dall'esperienza dei fascismi europei e controllato da nazionalisti arabi radicali. Esso mirò a diffondere gli ideali del nazionalismo arabo mobilitando gli iracheni contro l'Impero britannico e facendo leva soprattutto sugli studenti. Nel dopoguerra vari esponenti del movimento si unirono ad al-Kaylani nel Partito Iracheno dell'Indipendenza.

Nadi al-Muthanna fu guidata da Saib Shawkat e dal suo braccio destro Muhammad Mahdi al-Kubba. Nel 1938, grazie alla forza crescente del movimento, Sami Shawkat fu nominato direttore generale dell'educazione  e, dietro suggerimento dell'ambasciatore tedesco Fritz Grobba, diede vita a un'organizzazione giovanile sul modello della Gioventù hitleriana, chiamata al-Futuwwa (parola legata all'Islam medievale e al sufismo). Un delegato dell'organizzazione partecipò al Congresso nazionalsocialista di Norimberga del 1938 e, a sua volta, il capo della Gioventù hitleriana Baldur von Schirach fu ospitato dal movimento iracheno. Il Daily Telegraph ha scritto che anche se non vi sono prove oggettive, è probabile che il giovane Saddam Hussein abbia fatto parte di un'organizzazione paramilitare simile a al-Futuwwa nata negli anni '50. Giunto al potere egli parlò varie volte con ammirazione della Gioventù hitleriana. Si ritiene inoltre che il panarabismo di Saib Shawkat abbia avuto una grande influenza ideale sul Partito Ba'th. Altro esponente di primo piano di Nadi al-Muthanna fu Yunis al-Sabawi, deputato e poi ministro dell'economia. Egli tradusse il Mein Kampf in lingua araba e veicolò messaggi politici di stampo antisemita. Nel giugno 1941 l'organizzazione partecipò a un pogrom antiebraico, noto con il nome di "Farhud".

Note

Bibliografia
 Elie Kedourie, Arabic political memoirs and other studies, 1974
 Youssef M. Choueiri, Arab nationalism: a history: nation and state in the Arab world, 2000
 Edmund Ghareeb, Beth Dougherty, Historical dictionary of Iraq, 2004
 Eric Davis, Memories of state: politics, history, and collective identity in modern Iraq, 2005
 Orit Bashkin, The other Iraq: pluralism and culture in Hashemite Iraq, 2009

Partiti politici iracheni
Partiti fascisti

redpajama_set_name: RedPajamaWikipedia


Gefen has announced the availability of two new digital signage media players, expanding the range of solutions it provides for this growing industry segment.
Gefen's Digital Signage Media Player with Wi-Fi.
Both Digital Signage Media Players with Wi-Fi offer a SMIL (synchronized multimedia integration language)-compliant media player that works with any computer LAN system, either by connecting directly to the LAN or by using the Wi-Fi connection. Users can playback 1080p Full HD video. These players also output component and composite video with two channel (L/R) audio and one-line scrolling text. Each player comes pre-loaded with more than ten templates to select from, so users can jump-start their digital signage applications with little to no design experience.
The Digital Signage Media Player with Wi-Fi offers 4 GB of internal flash memory and the secure flash card slot can host up to 16 GB of memory, if needed. Keyboards, mice, hard drives and more can be connected through the two USB 2.0 ports.
The Digital Signage Media Player with Wi-Fi Plus offers the same features but with the added ability to connect live video using a composite video input with audio. Users can also overlay content and separate the video into four quadrants for more complex systems. RS-232 for control of external displays or other connected devices is also included.
Both players support popular media formats, including MPEG-1, MPEG-2, MPEG L2, MP3, H.264/MPEG-4, and VC-1 codec formats. Gefen provides a number of optional CMS (content management system) providers for both players.


Wellington's annual International Dance Day was established by Youthdance Education Trust (YET) in 2000. YET is a Wellington registered charitable trust with two aims: to support young people in dance and to support those who work with young people in dance.
YouthDance Education Trust, winner of the Wellington Arts and Culture Award at the 2013 Wellington Airport Regional Community Awards.
International Dance Day is part of UNESCO's World Dance Day, an event established on the 29th April 1986. The chosen date celebrates the birth of Jean-George Noverre (1727-1810), the creator of modern ballet. Dance crosses all political, cultural and ethnic barriers and the aim of the day is to bring people together in peace and friendship through the common language of dance. International Dance Day is free to all participants, in common with other celebrations around the globe.
International Dance Day enables Wellington's diverse cultural, theatrical and social dance organisations to come together to share ideas, learn new dances, new dance styles, perform to new audiences and celebrate in dance. Professional dancers, amateurs and school groups from the public and private sector participate.


Skydive Oz is coming to Dubbo! Embrace your fear, hop in the plane to take in your 'backyard' during the 20 minute scenic flight to 14,000 feet.
Feel free to scream at the top of your lungs as you free-fall for 60 seconds at over 200 kilometres per hour. Then enjoy floating down under canopy over the beautiful countryside for about five to seven minutes soaking up views of Dubbo city, the Macquarie River, and Western Plain Zoo. We have a unique, fun, relaxed and safe atmosphere to ensure you have the absolute most amazing skydiving experience possible!
Everyone is welcome to join us at the Aero Club! Watch your friends and neighbours as they experience the thrill of a lifetime.


text:
The Productivity Commission thinks Australia will be better off with fewer writers and fewer publishers. By Michael Heyward.
Michael Heyward
Parallel importation and the attack on local publishing
The Productivity Commission has an irrational obsession with destroying the livelihoods of writers. This is the only conclusion I can draw from its draft report on intellectual property. It has an intemperate and profoundly unbalanced hatred of the concept of literary ownership.
Take one recommendation: By the end of 2017, the commission would abolish the qualified territorial copyright arrangements, or parallel import rules, we have in Australia. These precisely limited arrangements, which have operated in Australia since 1991, make copyright enforceable in Australian book publishing. Without this market mechanism the ability of Australian writers and publishers to compete for the benefit of Australian consumers will be eroded.
If the draft recommendations are adopted, it will damage the wellbeing and long-term interests of people who buy books, and harm the ability of writers and publishers to be entrepreneurs and to innovate. It will be harder for new players to enter the market. Far from encouraging competition, the removal of territorial copyright will freely transfer revenue to huge foreign retailers, wholesalers and publishers because they will continue to benefit from territorial copyright in the other major English-language territories. No significant English-language market other than New Zealand has done as the Productivity Commission would have Australia do. But books aren't cheaper in New Zealand, and its publishing industry has withered since it tossed territorial copyright into the Tasman.
The commission assumes its recommendations would reduce book prices. None of its assumptions about prices are tested. The Productivity Commission has done no research on price since it delivered its previous report, in 2009. Yet, since 2008, the average selling price of printed books has fallen by at least 25 per cent in Australia.
The commission's draft report is a covert arts policy, designed to take us back to the days when Australia was a publishing colony.
The commission has a duty to put its assumptions to the test. It ought to do its homework on price before it recommends fracturing our extraordinarily successful book culture. There have been no Australian Bureau of Statistics data on the industry for more than a decade. Back in 2009 the commission confessed it was unable to measure the effect of parallel import rules (PIRs) on prices or to predict what would happen to prices if they were removed.
In September 2009, it said: "In summary, while it is not possible to provide a definitive estimate of the effects of PIRs on book prices, or an unequivocal prediction of market-wide price movements in their absence, the evidence assembled during the study enabled the Commission to draw conclusions about those price impacts that, in its experience, are sufficiently robust for assessing the merits of policies such as PIRs."
This Alice-in-Wonderland logic remains painful to read. It is a marvel of nature that any report could ever draw robust conclusions in the absence of definitive estimates or unequivocal predictions.
Understanding the importance of territorial copyright for the publishing industry begins with the Copyright Act, which is based on the inherent right of ownership that attaches to creative effort. But the Copyright Act cannot fulfil its objectives in the absence of territorial copyright because without it writers cannot enforce the contracts they sign. Without enforcement, they cannot compete.
The current rules not only encourage competition – they make it possible because they grant Australian writers and publishers the same territorial rights that writers and publishers have in other English-language markets.
Australia has an impressive diversity of booksellers, who operate in the fairest and most liberal territorial copyright regime in the English-speaking world, because the 1991 amendments balanced the interests of all parties. As a consequence, our independent bookselling sector has real market clout and sets international standards. This prescient reform ensured books would be made available to readers in a timely fashion, thus protecting the competitive interests of booksellers. It permitted parallel importation – the purchase of a competing edition from an overseas supplier – for personal use, allowing readers to buy books from all over the world, and it permitted booksellers to parallel import upon customer request.
All this applied downward pressure on prices and created powerful incentives for our industry to operate efficiently. I am appalled that the commission believes that Australian territorial copyright rules "distort the allocation of resources from their highest value uses".
What the Productivity Commission means is that Australia will be better off with fewer writers and fewer publishers. The Turnbull government, which has not bothered to announce an arts policy, has already declared it will adopt the commission's draft recommendations. In fact its policy has been declared for it by the Productivity Commission, and its purpose is to reduce the number of Australian writers and publishers and to diminish Australian literary culture.
The draft report notes that Australia is a net importer of copyright. The fact is that every writer whose book is published in the United States or Britain, or any other market, is a net exporter of copyright. Some publishers, such as Text, are net exporters of copyright. The dismantling of territorial copyright, to the extent that it disabled the export of Australian writing, would damage entrepreneurial creators and producers, and so erode Australian culture. The beneficiaries of this erosion will be foreign wholesalers and retailers who will become free riders in our market.
Abandoning the rules will strip writers of royalties they would otherwise earn. Here's why. Publishers pay domestic royalties to authors for books they sell in their home territory. For books sold in foreign territories authors are paid export royalties – commonly about one-third the value of a domestic royalty. The overwhelming majority of Australian authors receive domestic royalties in Australia and the overwhelming majority of foreign authors whose books are distributed here earn export royalties. In general, the only foreign writers receiving domestic royalties from sales in Australia are those who have licensed their books to Australian publishers, just as Australian authors receive domestic royalties in foreign countries when they license their books to publishers in those countries.
The Productivity Commission wants to believe our rules favour foreign writers. If this is true, is it then in favour of territorial copyright in the US and Britain because the rules in those countries must therefore benefit foreign copyright holders, such as Australian writers? Or does such revenue merely encourage Australian writers to persist with the inefficient allocation of their resources into books?
The fact is that our qualified territorial copyright benefits Australian writers most because Australian writers are in general paid much higher royalties here. Abandoning territorial copyright will benefit foreign copyright holders at the expense of Australian copyright holders simply because the volume of foreign books sold here will increase, and the volume of Australian books will decrease, whether or not there is any measurable impact on prices. Australian writers will begin to earn export royalties on foreign editions of their books sold in their own country, so their incomes will fall, a welcome trend in the eyes of the commission since it will be evidence its recommendations are working.
Trading in rights is critical to any modern publishing industry. The benefits of selling the territorial rights of Australian authors abroad should be obvious: greater audience and royalties, the export of Australian culture. The benefits of buying Australian territorial rights from foreign writers are also widespread. The books of these writers are printed in Australia, creating jobs. Their contracts are negotiated in Australia, creating jobs. Their books may be edited for Australian conditions, creating jobs. Their books may be designed in Australia, creating jobs. The Australian publishing industry supports 20,000 jobs. It is worth $2.2 billion, bigger than film and recorded music combined.
The removal of territorial copyright will shrink every aspect of our industry: fewer authors published, fewer books printed, fewer Australian-made books sold. The rights market will be eroded because it will no longer be possible to define Australia as a publishing territory.
No publisher will be exempt. At Text, for instance, the foreign revenue we earn by selling rights considerably exceeds the royalties we pay as a consequence of Australian sales. Most of this foreign revenue flows through to our Australian writers. The value of our books in print outside Australia is greater than the value of our original domestic editions. It shows what can be achieved if we conceive of Australia as a sovereign territory upholding the same rights in copyright as our international competitors. And it shows the threat to fair competition and entrepreneurial risk-taking if those books, produced because we have licensed rights outside Australia, can boomerang back into this market as free riders. There's a lot at stake. As much as a third of our company's revenue is generated internationally. About two-thirds of the royalties we pay our writers are generated internationally.
Any proposal to dismantle territorial copyright is in fact a radical instrument of reverse cultural engineering, which is why the Productivity Commission's draft report is a covert arts policy. It is designed to take us back to the days when Australia was a publishing colony. Who in the commission's brave new world is going to publish in Australia the large number of Australian writers who also have international readerships? The answer is foreign companies who will be competitively advantaged by the absence of territorial copyright here. It is not in Australia's interest for Australian copyrights to go offshore and for Australian culture to be curated elsewhere. And who is going to publish debut authors, the bestsellers and prizewinners of tomorrow? Fewer publishers, I would suggest, taking fewer risks. But that's good news for the Productivity Commission and the Turnbull government because, in the efficient reallocation of resources to value uses higher than literature, there will be fewer writers too.
This article was first published in the print edition of The Saturday Paper on Jun 18, 2016 as "Closing the books".
Michael Heyward is publisher of Text Publishing.


Imiza is also known as 'The village of dream'.
This perched village located in the Cap-Corse region offers a panoramic view over yhe gulf of Saint-Florent, the Agriates desert and the town of Ile-Rousse.
IMIZA invite you to discover an authentic, essential and attractive cosmetics range.
Offer your body a true skincare programme with products from the protected Corsican countryside.
Our research has produced products of a high standard.


text:
package laika.ast.sample

import laika.ast.{Document, DocumentTree, DocumentTreeRoot, TemplateDocument}
import laika.config.Config.ConfigResult
import munit.Assertions

trait DocumentTreeAssertions extends Assertions { self =>

  implicit class DocumentTreeRootEitherOps (val root: ConfigResult[DocumentTreeRoot]) {

    def assertEquals (expected: DocumentTreeRoot): Unit = {
      root.fold(
        err  => Assertions.fail(s"rewriting failed: $err"),
        root => root.assertEquals(expected)
      )
    }

  }

  implicit class DocumentTreeEitherOps (val root: ConfigResult[DocumentTree]) {

    def assertEquals (expected: DocumentTree): Unit = {
      root.fold(
        err  => Assertions.fail(s"rewriting failed: $err"),
        root => root.assertEquals(expected)
      )
    }

  }

  implicit class DocumentTreeRootOps (val root: DocumentTreeRoot) {

    def assertEquals (expected: DocumentTreeRoot): Unit = {

      root.tree.assertEquals(expected.tree)

      self.assertEquals(root.allDocuments.map(_.path), expected.allDocuments.map(_.path), "tree structure differs")

      (root.coverDocument, expected.coverDocument) match {
        case (Some(actual), Some(exp)) => actual.assertEquals(exp)
        case _ => ()
      }

      self.assertEquals(root.staticDocuments, expected.staticDocuments, "number or names of static documents differ")

    }
  }

  implicit class DocumentTreeOps (val tree: DocumentTree) {

    def assertEquals (expected: DocumentTree): Unit = {

      def validateStructure(): Unit = {
        self.assertEquals(tree.allDocuments.map(_.path), expected.allDocuments.map(_.path), "tree structure differs")
      }

      def validateContent(): Unit = {
        tree.allDocuments.zip(expected.allDocuments).foreach { case (actual, expected) =>
          actual.assertEquals(expected)
        }
      }

      def collectTemplates (tree: DocumentTree): Seq[TemplateDocument] = tree.templates ++ tree.content.collect {
        case child: DocumentTree => collectTemplates(child)
      }.flatten

      def validateTemplates(): Unit = {
        val actualTmp = collectTemplates(tree)
        val expectedTmp = collectTemplates(expected)
        self.assertEquals(actualTmp.map(_.path), expectedTmp.map(_.path), "number or names of templates differs")
        actualTmp.zip(expectedTmp).foreach { case (actual, expected) =>
          self.assertEquals(actual.content, expected.content, s"difference in content of template '${actual.path.toString}'")
        }
      }

      validateStructure()
      validateContent()
      validateTemplates()
    }

  }

  implicit class DocumentOps (val actual: Document) {

    def assertEquals (expected: Document): Unit = {
      val doc = s"of document '${actual.path.toString}'"
      self.assertEquals(actual.content, expected.content, s"difference in content $doc")
      self.assertEquals(actual.title, expected.title, s"difference in title $doc")
      self.assertEquals(actual.fragments, expected.fragments, s"difference in fragments $doc")
    }

  }

}

redpajama_set_name: RedPajamaGithub


This outdoor monument is a tribute to the 'Ma'apilim," or the Jewish blockade runners who bypassed the British during Mandate times to immigrate to pre-state Israel. Address: Tel Aviv boardwalk near Bograshov St.
Founded by the Zionist Organization of America in the early 1950s, the veteran cultural institution offers a diverse selection of arts, entertainment and nightlife options.
Established in 1966 and named after the famous author, this institution to promote Yiddish culture houses a library and archive, and offers classes and exhibitions. Address: 4 Berkowitz St.
Created in 1937, the center devoted to the life of Zionist leader and Irgun resistance group co-founder Ze'ev Jabotinsky houses a museum and historical archives.
Azrieli Center is one of Israel's most impressive malls, with dozens of stores, restaurants and a multiplex cinema. Among the center's biggest draws is the Middle East's highest observation platform (187 meters tall), which offers a breathtaking panoramic view. Address: 132 Menachem Begin Rd. at HaShalom Rd.


Clone process worked fine and the new disk booted OK however it did the 'load desktop' thing and failed to start explorer. The reason being is that the source disk contained windows 7 on the H: drive and the clone put it on the C: drive. So now windows 7 is confused enought to see user profiles but cannot load them and cannot find many of it's applets.
Setting the source system to C: is not an option as that requires a reinstall of the OS so how can Migrate Easy persist the H: drive letter for the boot OS?
I think the problem as far as W7 is concerned is that the W7 boot manager can reference installations by reference or by fully qualified path, when cloning to another drive especially one that is different in size, the sectors where the OSs start as far as the BCD database are concerned are now wrong, so it will either not boot Windows or reference the wrong place.
So what is the short answer, Migrate Easy does not work for windows 7 if the OS is NOT on C:?


Looks like I have not been keeping tabs on this brand. I have just found out that Stowa has issued a Limited Edition run of 70 pieces of their very popular Stowa Airman for Taiwan. I suspect this is in collaboration with the local Taiwan distributor of Stowa.
This limited edition watch, the Stowa Flieger is powered by a hand wound movement, the ETA 2801. It is logoless, i.e. the dial is sterile and features blue hands. It has a solid back and it is engraved with the limited edition run serial number. I like it. I actually thought of getting it and selling my Stowa no logo no date COSC Airman and replacing it with this.
The case back. I believe the TW/LE/2010 indicates it is Limited Edition Taiwan produced in 2010.
Hi there, this is a nice watch.
Is it selling in Taiwan already? And where can I get it?
Any more details on the pricing as well?
Welcome to the blog. With regards to the watch, it is currently being sold, well as of April 9, there was 1 piece, by the Stowa distributor here in Taiwan. I am not sure of the price of the watch as I did not ask. The distributor is located near Taipei 101, but I do not know the exact address.


At Sage, we've been supporting businesses like yours with world-class business software for well over a quarter of a century. Our long-term commitment to investing in technologies and applications helps you to stay ahead in a rapidly changing world.
Many of today's organizations recognize the need to link their business processes with a broader approach. This is necessary to drive down costs, compete with larger rivals, and empower employees to collaborate more effectively. This call for an integrated approach has been answered with Sage MAS 90 and 200 Extended Enterprise Suite, featuring end-to-end software connectivity that dynamically links processes, information, workflows, and communication channels. Extended Enterprise Suite simplifies tasks, reduces redundant data, and provides unrivaled information transparency.
Extended Enterprise Suite helps organizations like yours coordinate your whole business: From customer-facing systems, such as sales and service, through back-office processes, including accounting and project management, to core activities, such as manufacturing and engineering.
With Extended Enterprise Suite, your staff works together more effectively while your limited or expensive resources are optimized. In addition, your managers have instant access to companywide information and are equipped to plan for the future of your growing business.
Extended Enterprise Suite includes the applications needed to manage information and processes in every part of your business. It supports you in managing the whole process of customer acquisition—from your initial marketing campaign and lead generation through your quotation process and successfully winning the order. And finally, to fulfilling your orders and providing outstanding customer service in the future.
Extended Enterprise Suite helps your employees access a more concise, accurate, and complete view of your customers and their every interaction with your organization, including sales and marketing, order dispatch, project management, and credit control. By integrating your business processes, Extended Enterprise Suite allows your staff to view the same data. Time previously spent reentering data is saved, and accuracy is improved while your customer requirements can be identified and fulfilled quickly and profitably.
All Extended Enterprise Suite applications can be quickly deployed and mapped to specific business requirements, ensuring that you are up and running quickly with software that's right for your business. You'll also have options to configure applications, and in many cases, the software can be customized fully by a Sage business partner to suit particular business processes.
We understand that every business has its own requirements in terms of functionality and level of integration needed. Extended Enterprise Suite provides your business with a solid and dependable software platform. The core modules in the suite are Financials, Distribution, Bill of Materials, and CRM, to which you can add extra users and modules such as Job Costing and Payroll, to meet your own business processes. Your business benefits from simplified ownership and a single point of contact and accountability, whether you have everything, on only a few of the available modules.
Extended Enterprise Suite supports operations specific to particular industries, notably Manufacturing and Wholesale Distribution. Beyond that, our alliances with third-party software developers give you access to an exceptionally wide range of specialized software options that can be integrated with your Sage solutions.
Managing the day-to-day running of your business, the Financials modules provide you with unrivalled business control and management reporting. They draw on information held in General Ledger, Accounts Payable, Accounts Receivable, Bank Reconciliation, and Fixed Assets.
Distribution adds Sales Order Processing, Purchase Order, Inventory Management, Return Merchandise Authorization and Credit Card Processing, to the Financials modules. By integrating your accounting and distribution modules, you can easily automate the delivery of customer orders with effective inventory management for complete control of your supply chain.
SageCRM is an Internet-based CRM solution, designed to bring the real benefits of Customer Relationship Management (CRM) to your organization. It's designed to be easy to use and deploy, affordable, and packed with useful features.
With SageCRM, you can quickly analyze, manage, and synchronize sales, marketing, and customer service activities across all points of contact.
The BOM module follows your bill of materials process from beginning to end. It breaks down the manufacturing operation into easy-to-access areas, including materials, labor, machines, operations, and reporting.
With our vast industry experience, we are perfectly placed to provide integrated systems that control the whole manufacturing process, from planning materials to monitoring real-time work orders. Manufacturing gives companies greater control over their manufacturing processes through effective scheduling of work, close tracking of resource utilization, and improved business analysis.
Designed to provide instant visibility across your business, our business intelligence tools combine to create all-encompassing information management so you can turn data into actionable knowledge. Our customizable report generation, inquiry, analysis, and charting features work seamlessly to increase your productivity, improve business financial reporting, and enhance functionality.


Getting through Great Yarmouth means crossing Breydon Water which can be rough in high winds.
This means planning ahead and crossing at the right times at low water. Don't attempt to cross in fog.
You'll need to cross Breydon Water if you want to cruise between the northern rivers (Bure, Ant and Thurne) and the southern rivers (Yare, Chet and Waveney).
If in doubt whether it's safe to cross, call Broads Control (01603 756056) or Great Yarmouth Yacht Station on 01493 842794.
Time your arrival in Great Yarmouth to coincide with the right tide - slack, low water or just after, which is approximately one hour after low water at Great Yarmouth Yacht Station. To find out when low or slack water is check the tide tables.
At slack, low water the current is weaker so it's easier to moor and there is more room under bridges. If you try to cross at high water you may not get under bridges and there is nowhere safe to wait for the tide to drop if you are on Breydon side.
It will take about 2¼ hours to get to Great Yarmouth from Acle and about 2 hours from Reedham or St Olaves.
Stay within posts - there is shallow water outside the posted channel.
Everyone should wear a life jacket, but especially when crossing Breydon Water.
Regular ranger patrols are made to coincide with high tide at Great Yarmouth Yacht Station during the summer and updates are passed regularly to the Yacht Station and Broads Control. If in doubt, check with Great Yarmouth Yacht Station 01493 842794. Passage should not be attempted in fog. You'll find additional information from rangers in our Breydon navigation notes.
Broads Authority Act 2009 (which amends various sections and definitions contained in the above).


text:
Q: Numbers do not appear in bibliography I am writing a report and the brackets in my bibliography remain empty, also the citations in text are question marks. How do I get numbers in them?
This is my code:
\documentclass[pdftex,10pt,a4paper]{report}

\usepackage{minitoc}
\usepackage{amsthm, amsmath}
\usepackage{listings}
\usepackage{color}
\usepackage{fancyhdr}
\usepackage{float}
\usepackage{geometry}
\usepackage[square,sort,compress,numbers]{natbib}
\usepackage[pdftex,colorlinks=true]{hyperref}
\usepackage[pdftex]{graphicx}
\usepackage{wrapfig}
\usepackage{notes}
\usepackage{watermark}
\usepackage{epstopdf}
\usepackage{sectsty,textcase}
\usepackage{blindtext}

\begin{document}
Some text \cite{carmeliet2000}.
Extra text \cite{alberts2002}.

\newpage
\bibliographystyle{plainnat}
\bibliography{allsources}

It shows the references in the bibliography, but does not put numbers in the brackets, in the bibliography as well as in the text.
allsources.bib looks like:
@ARTICLE {carmeliet2000,
author  = "Peter Carmeliet and Rakesh K. Jain",
title   = "Angiogenesis in cancer and other diseases",
journal = "Nature",
year    = "2000",
volume  = "407",
pages   = "249-257",
month   = "sep",
DOI     = "doi:10.1038/35025220"
}

@BOOK {alberts2002,
author    = "Alberts B. and Johnson A. and Lewis J. et al",
title     = "\textit{Blood Vessels and Endothelial Cells} in Molecular
Biology of the Cell",
publisher = "New York: Garland Science",
year      = "2002",
edition   = "fourth"
}

A: Just check the attached image. If you are using tex studio, go to Tools -> clean auxiliary files, then run the file twice.

redpajama_set_name: RedPajamaStackExchange


text:
Marc Webb Teasing Venom In 'Amazing Spider-Man 2'?
Posted February 7th, 2013 by Ben Silverio
Earlier this week, we learned that 'The Amazing Spider-Man 2' began production and last week, we found out that the film would be shooting entirely in New York. We also got official word that villains Electro, played by Jamie Foxx, and Rhino, played by Paul Giamatti, would be featured in the film. With those rogues lined up to cause trouble, Andrew Garfield's Peter Parker is sure to have his hands full, but could another rather popular villain be making an appearance in the film as well?
Screen Rant shared the following picture from Marc Webb's Twitter, where the director has been sharing various shots from the Spidey set. The picture looks to be a filing cabinet or a locker. Seemingly random, yes? Well, word around the rumor mill is that this locker is connected to the symbiotic super villain Venom. Check it out below:
But what could a locker featuring the number 14 have to do with Venom? Well, let's start with the hashtag. #happybirthday could refer to Dane DeHaan, who's birthday was on February 6th, which was less than an hour before the picture was taken. The director probably snapped the shot during a late night shoot with DeHaan on set. The 'Chronicle' star is set to play Harry Osborn in the film, and the character is more traditionally connected to the Green Goblin, but in some versions, like the new 'Ultimate Spider-Man' cartoon on Disney XD, he takes on the symbiote to impress his father by one-upping Spider-Man.
Still, that doesn't explain the locker. Well, in the 'Ultimate Spider-Man' comic books, Peter and Eddie Brock find an experiment meant to cure cancer in a locker that belonged to Pete's father at Oscorp. The parasitic concoction bonds with Peter first, making him a stronger Spider-Man, but after he rejects it, it bonds to Brock and the iconic foe is born.
It's very possible that Webb, along with writers Alex Kurtzman, Roberto Orci, and Jeff Pinkner, borrowed from the various stories of Harry and Venom and adapted them to their needs. It's also very possible that everyone is over-analyzing this. Either way, it's interesting an interesting theory to speculate on.
What do you think about the latest rumors about 'The Amazing Spider-Man 2'? Do you think Dane DeHaan's Harry Osborn will come out of this movie as Venom and then spin off into the long-rumored film from 'Chronicle' director Josh Trank? Or is this just a random picture that fans are over-thinking? Share your thoughts in the comments below!
'The Amazing Spider-Man 2' starring Andrew Garfield, Emma Stone, Jamie Foxx, Shailene Woodley, Dane DeHaan, Colm Feore, Paul Giamatti, and Sally Field is set to hit theaters in 3D on May 2, 2014.
Alex Kurtzman
Colm Feore
Jeff Pinkner
Roberto Orci
The Amazing Spider-Man 2
Ben Silverio
Ben F. Silverio received a degree from Drexel University in the Screenwriting and Playwriting Program with a minor in Television Production. While at Drexel, Ben co-founded and co-hosted a film review show called The Pretentious Film Majors, which has evolved into a multi-format form of entertainment including blogs, podcasts on iTunes, articles in the school paper, and a potential tv show. Now armed with an extremely expensive piece of paper, Ben can begin climbing the treacherous ladder of the entertainment industry, which he hopes to do while streaming WWE wrestling matches, reading Marvel comics, and blogging about the excessive amount of movies and tv shows that he watches, all on the iPhone that is permanently attached to his hand.
BBC Three Axes UK's 'Being Human'
Dreams of Building the Death Star Continue in Great Britain
Every Wish You Could Destroy Cities As 'Godzilla'? A New Online Game Let's You Do Just That!
'Titans' Producer's Comments May Hint At The TV/Movie Futures For Batgirl, Dick Grayson, Cyborg And More
Ryan Reynolds And Will Ferrell Set To Star In Musical 'A Christmas Carol' For Apple TV+
J.J. Abrams Is "Not Screwing Around" When It Comes To 'The Rise Of Skywalker'


Dr. Shilen Lakhani, MD is a gastroenterology specialist in Reston, VA and has been practicing for 12 years. He specializes in gastroenterology.
×Post a ResponseAre you Dr. Shilen Lakhani, MD?
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Check the quality of care at hospitals where Dr. Lakhani treats patients.


Kylie Jenner was reportedly unimpressed by her ''low key'' baby shower that took place in her back garden as her boyfriend Travis Scott wasn't there and her friends weren't allowed to take pictures for fear they would leak onto social media.
Kylie Jenner was unimpressed by her ''low key'' baby shower.
The 'Keeping Up With The Kardashians' star is reportedly expecting her first child with her boyfriend Travis Scott but was disappointed when her bash to celebrate the impending arrival fell short of her sister Kim Kardashian West's baby shower, which was just a day before.
A source said: ''Kim got the VIP treatment for her baby shower, it was naturally an out of this world, no expenses spared celeb packed event with Kim as the star of the show. Kylie's by contrast took place a day later and was much more low key.
And Kylie, 20, was ''upset'' her boyfriend couldn't make it or that her friends couldn't document it on social media as things had to be kept secret before the big reveal on the family's E! reality show.


text:
BREAKING: Tree falls onto car in Offaly as crowds head to Ploughing 2018
A large tree has fallen on a car on a busy Offaly road this morning as thousands make their way to Day 2 of the National Ploughing Championships.
It is reported that the tree came down on the car at Lahinch Cross, Kilcoursey, Clara on the Clara to Kilbeggan road. The route is being used by traffic heading to the National Ploughing Championships in Tullamore.
Gardaí, ambulance and fire services are attending the scene.
It's understood one occupant of the car has sustained minor injuries.
Also read: Fallen trees and debris being removed on north Longford roads this morning
This news comes just hours after another tree came down on a road near Cadamstown in Offaly. Storm Ali continues to ravage the country with 80km/h winds and gusts of up to 130km/h.
A Met Éireann weather warning for strong winds remains in place in Offaly and 16 others counties until 1pm.
Check out the Longford Leader National Ploughing Championship coverage HERE
The National Ploughing Association announced that it would delay the opening of Day 2 in Tullamore until 11am on Wednesday morning due to the weather.
It's expected that close to 100,000 people have been making their way to the site from all over the country from early this morning.
Also read: Opening of National Ploughing gates 'delayed until further notice'


Padmaavat Enters The 100 Crore Club In Just 4 Days!
Padmaavat box office collection is as much the audience's response to the film's creative merit as to the hate mongers and the fringe groups. Despite widespread protests against the Sanjay Leela Bhansali film even after the Supreme Court ordered state governments to maintain law and order during its release, Padmaavat has managed to emerge victorious at the box office.
Despite widespread protests against it and no screening in few states, Sanjay Leela Bhansali's epic period drama Padmaavat has turned out to be an absolute winner at the Indian box office. The movie in just 4 days has crossed the 100 crore mark and entered the Koimoi's 100 crore club!
The movie stands with a total of 114.00 crore at the box office. Since Padmaavat is a solo release, the collections are expected to remain steady at least till February 9 when Akshay Kumar-starrer female hygiene drama PadMan and Neeraj Pandey-directed thriller Aiyaary will arrive in the cinemas.
Thanks to Karni Sena, Bhansali's film grabbed eyeballs much before its release, and the anticipation in the fans was palpable. And this eagerness translated into big numbers at the ticket windows.
The film has been in the eye of a storm ever since the filmmaker began shooting in Jaipur. Several groups have been protesting against Padmaavat, alleging that the film distorts history and demeans the honour of Rajput queen, Rani Padmini.


The Dynamic Interface Between Clutter And Direction.
The Interface Between Clutter And Direction.
Both are acceptable, but the word Dynamic was introduced because of the drive that an individual naturally has when the clutter in their environment is no longer there.
In physical terms, the "Empty Desk" does not really exist, you are either one side of it or the other. It is just like the tick mark that signifies agreement. You start with the down stroke, which says I/ we have sorted/ got rid of the clutter. You then immediately go into the upstroke to confirm that everything follows the direction in question.
Clutter acts as a block and can have the effect of frustrating or stopping the progress of what you are doing, or what you are trying to do. The result is that you try to go faster, you are under pressure, but the fact is that you become more susceptible to making mistakes and end up going slower.
The words Dynamic and Direction could give the impression that you go off at speed but, with the absence of clutter, you realize that you are already at where you were trying to go. The emphasis, in proper direction, turns out to be communication rather than speed.
There is a school of thought that a certain amount of disorder is necessary to bring about success. The finding here by "Empty Desk" is that it is important to differentiate between "clutter/ disorder" and "full/ empty". Study, by definition, indicates a degree of untidiness. The same thing in production would be clutter. The question, when looking at a document, is – "Is it part of the structure of what is in communication?" In other words "If it is not an item which is a part of, or helping you with, what you are currently in communication with, why is that document there?" In a group activity, this could be – "why are you there?" i.e. Should you be somewhere else?
Albert Einstein's desk was not cluttered, it was full. He knew what was going on and that was all that mattered. He had an "Empty Desk" i.e. a desk empty of clutter!


Pickleball is back this year on Mondays, Tuesdays, and Thursdays starting on October 1. You need to register and pay a mere $10 for the season to participate so that insurance is covered. See page 29 of the Loyalist Township Recreation Guide under Adult Programs for details. All levels welcome. Great fun!
To register call 613.389.3648 or 613.634.5355 during business hours. Or online: www.loyalist.ca/go/register Payment options are Visa or MasterCard.
Shared paddles and balls are available.


GLOCK has a new model, the G30S (Slim), originally designed for an elite law enforcement unit and a great firearm for concealed carry. The GLOCK Engineers took the slender GLOCK 36 in .45 AUTO and paired it with parts from the big-bore GLOCK 30 SF. The GLOCK 30S has a 10+1 capacity magazine and can also except the GLOCK 21 magazine that holds 13 rounds.
After examining the G30S I was not disappointed, it has the external qualities from GLOCK you have grown accustom to; the paradigm-setting polymer receiver, The GLOCK SAFE ACTION fire control system, allowing the shooter to use three independent automatic safeties fast; a super-hard, corrosion-resistant, low-reflective external finish on the slide, barrel and GLOCK night sights; and the GLOCK standard cold-hammer-forged barrel with octagonal rifling for the .45 AUTO cartridge. When I was walking up to the table the G30S appears identical to a GLOCK 30, but when I reached the booth I noticed the G30S slide was actually thinner then the G30's.
When I picked up the GLOCK 30S it fit comfortably in my hand, you can feel the Short frame/Gen4 frame design immediately.
Atticus with his larger hands still said it was comfortable in his hands. Over all I really liked the gun and would use it for my own personal carry.
With the holidays quickly approaching I know you are starting to think about what to get the women in your life for the holidays. Good news, your search is over! Personally I celebrate Christmas and would love to see any of the items in the article under my tree, so I know the gal shooters in your life will love this stuff.
While doing research one night I came across The Well Armed Women, and they have some very beautiful jewelry that any woman, shooter or not, would absolutely love. I know I do! For the shotgun shooter in your life, look into getting her a "Shot Through the Heart" brass or silver heart pendant with a Winchester 28 gauge shotgun shell, gun and heart charm for $49.99!
So I am so excited about the next product! Urban Moxy is the first conceal carry purse that doesn't look like an old lady's bag! Krista, the designer of the purses, knows firsthand what a lady is looking for in a purse for her firearm. This purse is kid friendly and by that I mean it has a special feature called "The locket pocket", and a dangle chain for easy grab and go. At the moment it does not fit a full size firearm but don't worry they are working on offering pocket-size options. The purse I fell In love with was the Nicole, it is $99.99. And that is a great deal for such I beautiful purse.
I don't know about your girl, but I love wearing t-shirts. Off Hand Gear has some of the cutest and comfiest shooting related shirts out there. The shirts are made in America, which I love, by American Apparel. And the cut of the shirts you just can't beat! They fit amazingly because they are shooting related shirts actually made for women! I personally was getting tired of not having any options other than the men's shirts at the gun shows!
I know I didn't showcase that much today for gift ideas but between the three sites I gave you I covered jewelry, purses and clothing. You can't say I didn't cover the basics for shopping for a girl! Good luck guys on the shopping, and don't forget you can get your girl presents anytime of the year and if it's shooting related… I have to say sir you hit the jackpot on finding a lady that loves shooting, she deserves to get a gift from one of these places.
I have worked at a shooting range for a number of years. We get people from all walks of life. Some of the people who come in scare the living daylight out of me, and some are welcoming and sweet. On my lucky days,I would have a cool shooter come in that would actually teach me something new. But, on my "not so lucky days", I'd have shooters, who would come in with terrible aim, and even worse attitudes. Having these combinations of people come in and out has left me with a lot of good and bad stories.
It was mid-July and it has to be at least a hundred degrees. We just got the after lunch rush and I felt like I was melting. I barely got to eat lunch myself. There were at least fifteen people waiting to get on the line and the heat was making everyone a little cranky. Myself and one other range officer were in charge of running three bays. Every lane had at least one shooter and things were getting pretty chaotic. That day had me at the max on my "stress odometer." On days like this one, I wouldn't recommend talking smack about any R.O., and definitely not to a regular customer. One of the great things about building a relationship with the regulars that come in is knowing that they'll have your back. On days like this one, this came in handy. Some rude guy decided to talk crap about me saying that I didn't know what I was doing, and had no business being a range officer. Normally this wouldn't bother me, but, due to the heart that was cooking everyone alive, I had no patience with this guy. I didn't sugar coat any of my impatience when I told him, "I am not going to kick someone off because you think you're special." This guy got so mad! As far as I was concerned, it wasn't my fault that he decided to come shoot at the same time as everyone else.
After storming off, one of my regulars informed me that this gentlemen was saying rude things about me behind my back. Yes, I am a girl, but no, that does not make me any less knowledgeable about guns, or less capable to run my line. To teach this guy a lesson, I decided to act exactly like the "ignorant girl" he thought I was. "Silly me" forgot how much AR-15's throw cartridges, almost right at the person next to them, and when it was finally time to get our new favorite person on the line, guess where I put him. That's right! I put him at the very end, in the tactical bay. All the brass was attracted to him, it must have been karma. Ironically this guy had a big mouth, and a little gun. Let's just say once he got on the line, he didn't shoot for very long.
The moral of this story is: Don't talk crap about your R.O.'s, especially if it's a female that knows what she is doing.
I am packing up my shooting gear for the range today not for myself but so I can head out with my sister to a girls night out shooting event here in Dallas, TX.
The Gun Bunny will be out with us and I will be getting pictures and interviews from a few of the shooters tonight.
(Ammoland.com)- As a gun reviewer, blogger and all-around avid gun enthusiast, I spend a fairly good amount of time at the range and gun shops for work. While not a new subject, something that has been rapidly increasing the past few years are female gun owners and recreational shooters.


text:
POP Congress Wrap-up - Newsletter No. 4
LA MANIF
Delegates to the PSI Congress express Solidarity with staff at the United Nations.
Trade unionists attending the PSI World Congress rallied yesterday at the Place des Nations in Geneva to show solidarity with workers of international organisations. Over 30% of the Unite Nations workforce are working in precarious positions, including short-term consultant contracts and unpaid internships. The issue of internships is a continuing concern for trade unionists as these forms of precarious employment are starting to replace entry level job opportunities for young workers.
"How can we even begin to address the problem of increasing job insecurity in other sectors when the UN, the cradle of Human Rights, is itself exploiting or excluding thousands of young people each year through unpaid fellowships?" said Rosa Pavanelli, General Secretary of PSI, before delegates gathered at the Place des Nations.
The General Secretary also called on the UN to change its administrative practices on unpaid status to "ensure that a budget allocation is made for all interns." Additionally, she called on the UN to review their labor policies "so that we all avoid precarious employment."
Solidaridad con el staff de la ONU expresó el Congreso de la ISP
Los sindicalistas que están asistiendo al Congreso Mundial de la ISP se congregaron ayer en la Plaza de las Naciones de Ginebra para mostrar su solidaridad con los trabajadores de las organizaciones internacionales. Más del 30% de la fuerza de trabajo de las Naciones Unidas está trabajando en posiciones precarias, incluidos contratos de consultores a corto plazo y pasantes no remuneradas. El tema de los pasantes es una preocupación constante para los sindicalistas, ya que estas formas de empleo precario están comenzando a reemplazar las oportunidades de trabajo de nivel inicial para los trabajadores jóvenes.
"¿Cómo podemos siquiera empezar a abordar el problema de la creciente precariedad laboral en otros sectores cuando la ONU, la cuna de los Derechos Humanos, está ella misma explotando o excluyendo a miles de jóvenes cada año a través de prácticas no remuneradas?", señaló ante los asistentes, Rosa Pavanelli, Secretaria General de la ISP, en un lugar que pocas veces ha recibido a tantos sindicalistas como es la Plaza de Las Naciones.
La representante de la ISP, además llamó a la ONU a modificar su instrucción administrativa sobre las prácticas no remuneradas "y garantizar que se lleve a cabo una asignación presupuestaria para todos los becarios". Además, debe revisar sus políticas laborales "con el fin de que todos evitemos el empleo precario".
The future of work in public services
"The labour market of the future is not yet formed, it will be what we make of it, said ILO Director-General, Guy Ryder in the panel on the future of work in public services on Wednesday morning. "Technology dominates almost every debate and article about the future of the labor market, but many other factors will have an influence, for example trade unions," he said. "Technology will not destroy as many jobs in the next 10 years as Lehman Brothers destroyed in the last ten years."
Karen Gregory, Lecturer in Digital Sociology, University of Edinburgh, UK, took up what she called Platform Capitalism. "Technology always changes the nature of work, it changes the infrastructure. Technology is never neutral, somebody owns it and has an agenda, but also, technology is labour."
Technology was a common theme for several panellists. Serena Sorrentino, General Secretary, Funzione Pubblica CGIL, Italy, added "new technology means workers need to have more professional skills. It will give greater strength to trade unions."
Marcelo Di Stefano, International Relations secretary for the Asociación del Personal de la Universidad de Buenos Aires, Argentina, said, "Technology can be an instrument for progress, for example in climate change, universal education or health. We need to take charge of technology and own it," he added.
Karen Gregory concluded by saying "Technology will continue to change the nature of work, but people, politics and culture matter."
Sustainable urbanisation and public services
Societies and working life are changing fast. More people than ever are moving from rural areas to cities in search for jobs and a better life. How can cities and municipalities handle the huge migration and be sustainable and offer quality public services at the same time?
The speakers in panel 4 with the aptly title Heaven or hell, should try to give good answers to these questions. Despite political differences in their countries, the panellists agreed that a strong, public sector is the best to take care of the inhabitants needs for available and public services of good quality.
-We have four simple answers to why welfare services should be the responsibility of public sector, said Mark Hancock, president in The Canadian Union for Public Employees. It is cheaper, quality is better, the availability is better, it gives the employees safer jobs and better wages. Now we have to convince the politicians that they should do as we say.
Ibrahim Khaleel Abudlkadir president, Nigeria Union of Local Government Employees explained that the most important fight now for his union and the members, is to ensure the independence of the 274 municipalities in the country. – According to the Nigerian Constitution, the municipalities should be secured money to drive their public services from the 36 states, but very often the money from the central state stops here. Because of this, many of our members have not got their salaries the last 4-8 months, said Abdulkadir.
-This is why it is crucial to win this time. We have the Nigerians people with us, our members are active and I do believe that we'll manage to change the Constitution this time.
Public services in a just global economy
"Public services are more important than we think. They are important both for the local communities, and also for maintaining stability in society," said Ann Pettifor, Economist at the City University and New Economist Foundation in South Africa, when she spoke in the panel "Public services in a just global economy" on Wednesday afternoon.
"We must not allow multinational companies to go offshore. They should be forced back on shore. They put themselves over the democratic system. As soon as somebody even mentions taxes, they disappear. But they are weak; they have lots of debt and are afraid of risk. The "roaring lion" of the public sector should step up and take control," she said.
Dennis Kristensen, president of the Confederation of Municipal Employees in Denmark told the audience about the Nordic welfare model.
"We are proud of our system. It is based on relatively high taxes which in turn pay for a high level of welfare. Unfortunately, we are moving in the wrong direction. In the old days, we agreed on the level on welfare and set the taxes in accordance with it. Now we do the opposite - taxes are lower and the level of welfare is reduced too. It's a race towards the bottom," said Kristensen.
Public policy for Sale?
"Among the first things Donald Trump did after becoming President was to make working conditions worse for public employees. We have to compete for our jobs, and services are outsourced and privatized very fast," said David J. Cox, President of the American Federation of Government Employees.
Cox continued to attack Trump in his opening speech in the panel Public Policy for Sale. "Trump attacks media, the freedom of speech, he wants to prohibit Muslims and he puts people up against each other. He wants to politicize the whole workforce and gives jobs to his republican friends. Do we want to be led by a republican or by a person who is competent to do their job?", Cox asked rhetorically. Former minister from Iceland and former PSI Executive Board member, Ögmundur Jónasson, approached the topic from a historical viewpoint. "There are three main reasons for privatizing," he said. "It's because someone wants to earn money, because it gives you power and access to policy decisions and policy development. The third reason is the aim to force public services into the same mould as the private sector. When public services are public it's much more difficult to implement cutbacks and to dismiss people," he said.
Ariel Pringles, Unión de Empleados de la Justicia Nacional, Argentina, emphasized the importance of highlighting problems concerning corruption and mistakes made by the politicians and big companies. "We need collective solutions and global strategies to disclose the consequences. We need international rules to protect the whistleblowers," he said.
"To stop the attacks on public services and public employees we must organise, organise and organise," said David Cox. Not only the panel, but the whole congress agreed with him.
PSI FILMS
One Day Premiere
RADIO LABOUR
KAREN GREGORY TALKS ABOUT THE NEGATIVES AND POSITIVES OF COMPUTER PLATFORM CAPITALISM
Karen Gregory, a professor of Digital Technology at the University of Edinburgh talks about the negatives and positives of computer platform capitalism.
RADIO LABOUR - SPECIAL REPORT
GUY RYDER WARNS NOT TO FOCUS SOLELY ON TECHNOLOGY
ILO Director-General Guy Ryder warns not to focus solely on technology as we consider the future of work.
3rd NOV - 08:00 - @ROOM 1+2+3+4
Pledge to #EndViolenceAgainstWomen
Promesa de poner fin a la violencia contra las mujeres
Engagement pour mettre fin à la violence faite aux femmes
#EndVAW - #MeToo - #Ihavesignedthepledge - #Ihave - #EndViolenceagainstWomen - #PSICongress2017
Don't forget to wear orange!
Panel 9 - Bread and Roses: Hearts starve as well as bodies
3rd NOV- 14:00h - @ROOM 1+2+3+4
Congress closing
Copyright © 2017 Public Services International, All rights reserved.


SWBAT compare texts to determine meaning and support their conclusions with evidence from the text.
The end is near…how will you respond?
Today is the beginning of my efforts to wind up our year on a positive note while keeping my students engaged. So, I open class today with a reminder that while the end is near, it's not over yet, and it is important to finish strong.
Classrooms that give in and "party" at the end of the school year irritate me, so this is my way of combating that. I want my students to see that while we celebrate their year and accomplishments, we still use our time wisely as they prepare for both the challenges of the end of the year and summer.
Then, we'll view the video below and discuss how it relates to their second half challenge - at a point when they are ready to throw in the metaphorical towel for summer, they have to rise to the challenge of not only state and local assessments but also making the best use of their time.
Sticking with my theme of challenge and not throwing in the towel, today students will read about two very impressive athletes. One they know - Jackie Robinson (and that will also snag my boys attention), but the other is someone I'm sure they aren't familiar with -a female boxer from Afghanistan.
Students will read the piece and use the graphic organizer to collect their thinking. Then, they'll complete the short answer questions.
Students will self-assess using the General Scoring Guide (displayed on screen) and turn in their work. This is not a new process for my students, so it takes only a few moments.


text:
Гвидо Густаво Гоццано (; 19 декабря 1883 — 9 августа 1916) — итальянский поэт и писатель. Один из крупнейших итальянских лириков XX века. Видный представитель, так называемой, «сумеречной» поэзии (crepuscolarismo).

Биография
Сын инженера. Из слабого здоровья окончил начальную школу с посредственными результатами. Окончил Национальный колледж Савильяно, в 1903 году поступил на юридический факультет Туринского университета. Однако с группой друзей предпочитал посещать литературные семинары поэта Артуро Графа, которые позже образовали группу Туринских поэтов Crepuscolari («сумеречной» поэзии), для которой характерны в противопоставление пышной риторике и традиционализму XIX века приглушенная меланхолическая тональность и подчеркнутая разочарованность в жизни.

Пессимизм в творчестве Гоццано объясняется ещё и тем, что он, страдая легочной болезнью, вынужден был большую часть времени проводить на курортах; о том, что умрет рано, он, конечно, знал. В мае 1907 года сильный приступ плеврита заставил его уединиться на Лигурийской Ривьере, затем в горных деревнях. В том же году вышла первая книга его поэзии «La via del rifugio».

В своём творчестве Гоццано испытал влияние бельгийских и французских поэтов-символистов и писателей (Ж. Роденбах, Э. Верхарен, Фр. Жамм) и немецкой философии, что отразилось в его стихах.

Автор двух поэтических сборников: «В поисках прибежища», 1907, и «Беседы», 1911; отдельные стихотворения, а также незаконченный цикл «энтомологических посланий» «Бабочки» увидели свет после смерти поэта. В 1914 году вышел из печати его путевой дневник «Lettere dall'India», написанный во время круиза в Индию (в 1912). Переписка Гоццано и его возлюбленной Амалии Гульельминетти была опубликована лишь в 1951 году.

В своих произведениях Г. Гоццано анализирует подсознательное и всплывающие в нём потоки ассоциаций, подобно тому как это делал в прозе Марсель Пруст; характерно для Гоццано также иллюзионистическое восприятие действительности и любовь к образам прошлого, в изображении которых он мастерски использует поэтические приемы соответствующей эпохи, преломляя их юмористически. Крайне утонченная, доступная лишь немногим и часто болезненная поэзия Г. Гоццано — поэзия аристократической верхушки интеллигенции.

Поэзия Гоццано близка к разговорной, в которой подчеркнута разочарованность в жизни (отсюда — склонность к описаниям тихой провинции, монотонных будней, больниц, монастырей; и демонстративная тоска по прошлому, по фамильным особнякам и буржуазным салонам минувшего столетия). При всём своём холодном эстетизме, Гоццано и остальные «сумеречные» поэты не чужды иронии, нередко иронизируя и над собой.

Значение Гоццано для современной итальянской поэзии — в его новаторских приемах. Гоццано, по словам Э. Монтале, одного из самых тонких исследователей его творчества, «был единственным среди поэтов своего времени, сумевшим оставить нам в небольшой книге песен собственный завершенный портрет».

Умер от туберкулёза в возрасте 32 лет.

Избранные произведения
 Поэзия
 La via del rifugio. Genua / Turin , 1907
 I colloqui, 1911
 Tutte le poesie, 1980
 Проза
 I tre talismani, 1914
 La principessa si sposa, 1918
 Viaggio verso la cura nel mondo. (1912—1913), postumi 1917
 L'altare del passato, 1917
 L'ultima traccia. Новеллы, 1919
 Primavere romantiche, 1924
 La moneta seminata e altri scritti, 1968
 Verso la Cuna del mondo — Lettere dall'India, 2005.

Литература
 Литературная энциклопедия. — В 11 т.; М.: издательство Коммунистической академии, Советская энциклопедия, Художественная литература. Под редакцией В. М. Фриче, А. В. Луначарского. 1929—1939.

Ссылки
 Gozzano, Guido
 Encyclopaedia Britannica. Guido Gozzano
 Гвидо Гоццано

Писатели-путешественники
Умершие от туберкулёза
Выпускники Туринского университета


While many fans will mark the day with a clever social media post, we're reminded of how the company behind "Star Wars" has famously used The Force -- of the law -- to try to protect its trademarks in court (with mixed results, as Motherboard has pointed out). Meantime, a search of FindLaw's archives reveals a few other "Star Wars"-related legal tales as well.
1. Lucas Sues Over 'Jedi Mind' Headset.
Back in 2010, a couple of scruffy nerfherders at Jedi Mind Inc. got themselves sued by George Lucas himself. The company claimed its headset product would somehow read a user's brainwaves to allow interfacing with games and other computer software.
Lucas sued them for infringing on a "Jedi" trademark owned by his film production company Lucasfilm. Lucas doesn't control use of the word "Jedi" in all contexts, but there are legal problems when a product has a potential to cause real confusion for consumers.
Plus, the "Jedi mind trick" is a well-known "Star Wars" reference wherein a Jedi uses telepathy to manipulate others. This headset purported to "read" your mind to manipulate a game or software. Our guess is that Jedi Mind settled with Lucas, as the company is now called Mind Solutions.
2. Man Kills Wife Over 'Star Wars' Toys.
"Star Wars" collectibles are a big deal in some circles, but are they worth killing for?
A British man, Rickie La Touche, seemed to think so, after strangling his wife for smashing items from his Luke Skywalker and Darth Vader collections. They didn't freeze him in carbonite, but La Touche will be most likely be spending the rest of his life in prison.
3. Man Jailed for Light Saber Attack at Toys 'R' Us.
Oregon resident David Allen Canterbury should be reaching the end of his probation for an impromptu light saber battle he instigated with Toys "R" Us customers in 2012. The misguided padawan was sentenced to 45 days in jail for the attack, and had two years added to his then-existing probation.
Hopefully Canterbury can avoid the allure of the dark side when his grant of probation is over.
Think of any other legal "Star Wars" moments we missed? Serve us a slice of knowledge pie with a glass of blue milk on Facebook or Twitter.


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text:
Hala är ett släkte av spindlar. Hala ingår i familjen vårdnätsspindlar.

Kladogram enligt Catalogue of Life:

Källor

Externa länkar

Vårdnätsspindlar
Hala


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text:
Home » Library » Sorry about the Sound Quality
Sorry about the Sound Quality
Improvisation, Living in the Moment and the Beauty of Mistakes
Hi, my name is Caroline Gillis and welcome to my audio interviews: Sorry about the Sound Quality: Improvisation, Living in the Moment and the Beauty of Mistakes.
I am an actress, mainly a theatre actress and in 2013 I went back to school to get my MA in Theatre Studies at the University of Guelph. As a graduate research assistant for ICASP (or Improvisation, Community and Social Practice) my task was to interview some of my friends and colleagues in theatre about improvisation, and about how they use it in their work and how it may have impacted their lives.
I've interviewed comedians, singers, voiceover actors, improv teachers, directors, writers and creators – and most of the artists I spoke to do a combination of all these things. Actors have to be improvisers on a daily basis, juggling many different types of work (creative and sometimes not) to keep body and creative soul alive. You will see how improvisation has positively affected the lives of these artists.
So, I hope you enjoy what these artists were kind enough to share, in a very personal way – and again "sorry about the sound quality."
INTERVIEW 1
Clare Preuss and Birgitte Solem
Hi, Caroline here. My first interview is with actors and creators Birgitte Solem and Clare Preuss. I worked with Clare and Birgitte at the Blyth Festival in Ontario years ago where we all acted together in a production of Anne (An adaptation of Anne of Green Gables). They share with us their insights on using improvisation as part of their work in everything from murder mysteries to interactive street theatre to teaching yoga. This interview immediately brought up themes that would continue to come up throughout my subsequent interviews: exploring the fear that some actors have of improv and why that is (Birgitte shares two very funny reasons why she thinks we can be so nervous about improv – so nervous that we can feel the "sweat on our fingertips" to quote her) – as well as themes about how we are all striving to live in the present moment and trying to be being open to inspiration. I interviewed the women in my apartment in Parkdale over pizza and beer. Hope you enjoy it and "sorry about the sound quality."
Nadia Ross and StoUnion
Hi, Caroline here. In my second interview about improvisation I interviewed Nadia Ross who is an actor, writer, director – well theatre artist – and is the artistic director of her own independent theatre company called StoUnion which is located in Wakefield, Quebec. Nadia and I met when we were both young actors and artists in Toronto and we were part of a collaborative creation in the early 90s called The Lorca Play which she references in her interview. It was a wild deconstruction of Lorca's House of Bernarda Albaperformed by seven women and one man. She talks about it in reference to how we create languages in theatre, in the same way musicians have a language. She is, incidentally, the daughter of a jazz musician and she shares some interesting thoughts on how that has affected her work. She's developed a language with her own company, and she has some fascinating things to share about inspiration and working with what she calls and "open system" which employs a lot of improvisation – and waiting. StoUnion also invites community involvement in its projects in Wakefield and I think you'll enjoy hearing about their yearly live television show.
I interviewed Nadia behind the Theatre Centre in Toronto where she was performing with her company in the show: What Happened to the Seeker? Hope you enjoy. Sorry about the sound quality.
Broadprov and Kate Ashby Academy
Hi, Caroline here. This is my third interview about improvisation in theatre and it's a pretty ambitious one. I interviewed eight women in my Parkdale apartment in Toronto. About 4 or 5 years ago I started taking improv classes with my friend, Kate Ashby, who had formed her own school for teaching improv, Kate Ashby Academy. One of the first classes she taught was called Broadprov – she started creating different names for the classes including a class called On Goldenprov which she created for seniors which you will hear referenced in a this interview as well as the following interview with a couple of Kate's other students. Broadprov consisted of professional female performers from many different avenues of acting and creating. This particular incarnation of Broadprov consists of comedians, theatre actors, writers, voiceover artists and singers. It was a magical class, to say the least, and so this interview was a reunion of sorts and actually becomes a little emotional at one point. When the class started some of us knew each other well, some a little, and some of us had never met at all. But if felt like something that was destined to be – a connection happened in that class that couldn't be denied. A lot of that had to do with trust, and with Kate creating a safe environment for us to work. Trust and feeling safe to create are themes that has come up over and over in these interviews, and this class provided that. It was therapeutic as well as creative. And it presents an interesting argument for process versus product which is also a common theme among theatre artists I've interviewed.
Unfortunately, I couldn't reunite the whole class for this interview but the "broads" that I were able to interview included: our teacher, Kate Ashby, and my classmates, Samantha Espie, Tracey Hoyt, Kirsten Johnson, Caroly Larson, Julie Lemieux, Teresa Pavlinek and Shoshana Sperling. I interviewed the women in my noisy home over drinks and sandwiches on a Sunday afternoon. Enjoy. Sorry about the sound quality.
Emily Hurson and Wendy Lands
Hi, Caroline here. This is the fourth interview in my series on improvisation – or theatrical improvisation and creation. In the previous interview I spoke with some students of Kate Ashby Academy – women from the original class of Broadprov. Broadprov has continued to morph over the years, with new female theatre artists joining the class as others left – but in fact some of the women have stayed with the class since its inception because of the positive impact it has had on their work and their lives. Here I interview Emily Hurson, an actor and a writer who was actually in the original Broadprov class (she couldn't make the reunion interview), and also Wendy Lands, a singer/songwriter and voiceover artist and actor who has been with Broadprov for the last few years. This interview is slightly unique in that I interviewed Emily and Wendy before and after an improvisational show of their work with Kate Ashby Academy – in this case a somewhat different type of presentation for them – their class, Broadprov, would meet for the first time on stage with the members of the senior's class, On Goldenprov. It was an interesting experiment with improv on stage – a kind of "pure improv" to borrow a term from my earlier interviewee Birgitte Solem. Kate would set up two person scenes and have them performed by one member of each class. Strangers (for the most part) meeting on stage. Again, we touched on themes of fear and anticipation which is especially present when one is performing in front of an audience – of friends and family for the most part – but as we hear from Wendy friends and family can sometimes be the scariest of audiences. We also have a quick cameo from Wendy's mom who watched the presentation that night.
I hope you enjoy this interview which took place in the lobby and then later the dressing room at the Ossington Street Theatre in Toronto. Sorry about the sound quality.
Kathryn Greenwood and Ed Sahely
Hi, Caroline here. In my fifth and final interview on improvisation, I speak with two of – probably the finest improvisers in the country – Kathryn Greenwood and Ed Sahely. It's an interesting look at how they found their way into improv and how it changed their lives. They share fascinating stories about their work with Second City, as well as their former company Not to Be Repeated which they co-founded with Jonathan Wilson. Kathryn also shares a bit about the creative process of the very successful sketch comedy troupe, of which she is a part – Women Fully Clothed. Kathryn and Ed illuminate a lot of the themes that have come up during my interviews and have really interesting slants on the frustrations, the joys and the importance of improv in their lives. They also come up with an interesting analogy between math and improv – "a blueprint" if you will. It's great to hear these long-time friends in conversation with each other – they are personifications of how trust, respect, inspiration and "just making each other laugh" work together to create some great art.
I interviewed Kathryn and Ed over wine and snacks (and lots of laughs) at my Parkdale apartment.
I hope you enjoy this final installment. It's been a pleasure (and sometimes a technological nightmare) to bring it to you. Sorry about the sound quality.
Sorry about the Sound Quality: Improvisation, Living in the Moment and the Beauty of Mistakes
Caroline Gillis Author


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BY AIR: Nearest Airport: Ben Gurion (Tel Aviv) - 45kms BY ROAD: Unless you know the layout of Jerusalem well, it is not recommended to drive to the royal Plaza/Lev Yerushalaym. A taxi from the airport will take approx. 40 minutes. The taxi should go to 8 Eliash Street, (near the Mashbir shopping mall) which is a suitable drop off point for clients and luggage. Guest should cross the pedestrian plaza to the Days Inn Jerusalem/Lev Yerushalaym which is on the far right hand corner of the plaza. Inform reception that you have luggage and they will send a porter.


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Original Research |20 October 2009
Effect of Fluticasone With and Without Salmeterol on Pulmonary Outcomes in Chronic Obstructive Pulmonary Disease: A Randomized Trial
Thérèse S. Lapperre, MD; Jiska B. Snoeck-Stroband, MD; Margot M.E. Gosman, PhD, MD; Désirée F. Jansen, PhD; Annemarie van Schadewijk, MSc; Henk A. Thiadens, PhD, MD; Judith M. Vonk, PhD; H. Marike Boezen, PhD; Nick H.T. ten Hacken, PhD, MD; Jacob K. Sont, PhD; Klaus F. Rabe, PhD, MD; Huib A.M. Kerstjens, PhD, MD; Pieter S. Hiemstra, PhD; Wim Timens, PhD, MD; Dirkje S. Postma, PhD, MD; Peter J. Sterk, PhD, MD; the GLUCOLD (Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease) Study Group
Thérèse S. Lapperre, MD
Jiska B. Snoeck-Stroband, MD
Margot M.E. Gosman, PhD, MD
Désirée F. Jansen, PhD
Annemarie van Schadewijk, MSc
Henk A. Thiadens, PhD, MD
Judith M. Vonk, PhD
H. Marike Boezen, PhD
Nick H.T. ten Hacken, PhD, MD
Jacob K. Sont, PhD
Klaus F. Rabe, PhD, MD
Huib A.M. Kerstjens, PhD, MD
Pieter S. Hiemstra, PhD
Wim Timens, PhD, MD
Dirkje S. Postma, PhD, MD
Peter J. Sterk, PhD, MD
the GLUCOLD (Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease) Study Group
Note: Drs. Lapperre and Snoeck-Stroband contributed equally to the study and the manuscript. Drs. Postma and Sterk also contributed equally to the study, the study supervision, and the manuscript.
Acknowledgment: The authors thank the patients for their cooperation in our study.
Grant Support: By the Netherlands Asthma Foundation (grant 3.4.93.96.3), GlaxoSmithKline of The Netherlands, University Medical Center Groningen, and Leiden University Medical Center.
Potential Conflicts of Interest:Consultancies: N.H.T. ten Hacken (Nycomed, Chiesi, Boehringer Ingelheim, GlaxoSmithKline), K.F. Rabe (GlaxoSmithKline), H.A.M. Kerstjens (GlaxoSmithKline, AstraZeneca, Nycomed), D.S. Postma (Altana, AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Teva). Honoraria: D.S. Postma (AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Nycomed, Teva, Top Institute Pharma), P.J. Sterk (GlaxoSmithKline). Grants received: M.M.E. Gosman (Glaxo Wellcome), N.H.T. ten Hacken (GlaxoSmithKline, AstraZeneca, Nycomed, Novartis, Boehringer Ingelheim), K.F. Rabe (GlaxoSmithKline), H.A.M. Kerstjens (GlaxoSmithKline, AstraZeneca, Nycomed, Novartis, Boehringer Ingelheim), P.S. Hiemstra (GlaxoSmithKline), P.J. Sterk (GlaxoSmithKline, Innovative Medicines Initiative).
Reproducible Research Statement:Study protocol: Available at www.clinicaltrials.gov. Statistical code: Available from Dr. Sont (j.k.sont@lumc.nl). Data set: Available from Dr. Sterk (p.j.sterk@amc.nl).
Requests for Single Reprints: Dirkje S. Postma, MD, PhD, Department of Pulmonology, University Medical Center Groningen and University of Groningen, Box 30.001, 9700 RB Groningen, The Netherlands; e-mail, d.s.postma@int.umcg.nl.
Current Author Addresses: Drs. Lapperre, Rabe, and Hiemstra and Ms. van Schadewijk: Department of Pulmonology, Box 9600, 2300RC Leiden, University Medical Center, Leiden, The Netherlands.
Drs. Snoeck-Stroband and Sont: Department of Medical Decision Making, Box 9600, 2300RC Leiden, Leiden University Medical Center, Leiden, The Netherlands.
Dr. Gosman: Department of Neurology, University Hospital Nijmegen, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands.
Dr. Jansen: Faculty of Medicine, Box 30.001 NL-9700-RB, University Medical Center Groningen, Groningen, The Netherlands.
Dr. Thiadens: Department of Public Health and Primary Care, Postzone V-0-P, Box 9600, 2300RC Leiden, University Medical Center, Leiden, The Netherlands.
Drs. Vonk and Boezen: Department of Epidemiology E3.29, Box 30.001, University Medical Center Groningen, Groningen, The Netherlands.
Drs. ten Hacken, Kerstjens, and Postma: Department of Pulmonary Diseases, Box 30.001 NL-9700-RB, University Medical Center Groningen, Groningen, The Netherlands.
Dr. Timens: Department of Pathology, Box 30.001 NL-9700-RB, University Medical Center Groningen, Groningen, The Netherlands.
Dr. Sterk: Department of Respiratory Medicine, F5-259, Academic Medical Centre, University of Amsterdam, Box 22700, NL-1100 DE, Amsterdam, The Netherlands.
Author Contributions: Conception and design: J.B. Snoeck-Stroband, H.A. Thiadens, H.M. Boezen, N.H.T. ten Hacken, J.K. Sont, H.A.M. Kerstjens, P.S. Hiemstra, W. Timens, D.S. Postma, P.J. Sterk.
Analysis and interpretation of the data: T.S. Lapperre, J.B. Snoeck-Stroband, D.F. Jansen, H.A. Thiadens, J.M. Vonk, H.M. Boezen, N.H.T. ten Hacken, J.K. Sont, K.F. Rabe, H.A.M. Kerstjens, P.S. Hiemstra, W. Timens, D.S. Postma.
Drafting of the article: T.S. Lapperre, J.B. Snoeck-Stroband, M.M.E. Gosman, D.F. Jansen, H.M. Boezen, J.K. Sont, K.F. Rabe, P.S. Hiemstra, W. Timens, D.S. Postma, P.J. Sterk.
Critical revision of the article for important intellectual content: T.S. Lapperre, J.B. Snoeck-Stroband, M.M.E. Gosman, H.A. Thiadens, J.M. Vonk, N.H.T. ten Hacken, K.F. Rabe, H.A.M. Kerstjens, P.S. Hiemstra, W. Timens, D.S. Postma, P.J. Sterk.
Final approval of the article: T.S. Lapperre, J.B. Snoeck-Stroband, M.M.E. Gosman, D.F. Jansen, H.A. Thiadens, J.M. Vonk, H.M. Boezen, N.H.T. ten Hacken, J.K. Sont, K.F. Rabe, H.A.M. Kerstjens, P.S. Hiemstra, W. Timens, D.S. Postma, P.J. Sterk.
Provision of study materials or patients: T.S. Lapperre, J.B. Snoeck-Stroband, N.H.T. ten Hacken, K.F. Rabe, H.A.M. Kerstjens, D.S. Postma.
Statistical expertise: T.S. Lapperre, J.B. Snoeck-Stroband, D.F. Jansen, J.M. Vonk, H.M. Boezen, J.K. Sont, D.S. Postma.
Obtaining of funding: P.S. Hiemstra, W. Timens, D.S. Postma, P.J. Sterk.
Administrative, technical, or logistic support: T.S. Lapperre, J.B. Snoeck-Stroband, H.M. Boezen, K.F. Rabe, H.A.M. Kerstjens, D.S. Postma.
Collection and assembly of data: T.S. Lapperre, J.B. Snoeck-Stroband, M.M.E. Gosman, A. van Schadewijk, H.A. Thiadens, J.M. Vonk, N.H.T. ten Hacken, J.K. Sont, K.F. Rabe, P.S. Hiemstra, W. Timens, D.S. Postma.
For a complete list of the GLUCOLD Study Group investigators, see the 4.
From Leiden University Medical Center, Leiden; University Medical Center Groningen, Groningen; and Amsterdam Medical Centre, Amsterdam, The Netherlands.
Inhaled corticosteroids (ICSs) and long-acting β2-agonists (LABAs) are used to treat moderate to severe chronic obstructive pulmonary disease (COPD).
To determine whether long-term ICS therapy, with and without LABAs, reduces inflammation and improves pulmonary function in COPD.
Randomized, placebo-controlled trial. (ClinicalTrials.gov registration number: NCT00158847)
2 university medical centers in The Netherlands.
114 steroid-naive current or former smokers with moderate to severe COPD.
Cell counts in bronchial biopsies and sputum (primary outcome); methacholine responsiveness at baseline, 6, and 30 months; and clinical outcomes every 3 months.
Random assignment by minimization method to receive fluticasone propionate, 500 µg twice daily, for 6 months (n = 31) or 30 months (n = 26); fluticasone, 500 µg twice daily, and salmeterol, 50 µg twice daily, for 30 months (single inhaler; n = 28); or placebo twice daily (n = 29).
101 patients were greater than 70% adherent to therapy. Fluticasone therapy decreased counts of mucosal CD3+ cells (−55% [95% CI, −74% to −22%]; P = 0.004), CD4+ cells (−78% [CI, −88% to 60%]; P < 0.001), CD8+ cells (−57% [CI, −77% to −18%]; P = 0.010), and mast cells (−38% [CI, −60% to −2%]; P = 0.039) and reduced hyperresponsiveness (P = 0.036) versus placebo at 6 months, with effects maintained after 30 months. Fluticasone therapy for 30 months reduced mast cell count and increased eosinophil count and percentage of intact epithelium, with accompanying reductions in sputum neutrophil, macrophage, and lymphocyte counts and improvements in FEV1 decline, dyspnea, and quality of life. Reductions in inflammatory cells correlated with clinical improvements. Discontinuing fluticasone therapy at 6 months increased counts of CD3+ cells (120% [CI, 24% to 289%]; P = 0.007), mast cells (218% [CI, 99% to 407%]; P < 0.001), and plasma cells (118% [CI, 9% to 336%]; P = 0.028) and worsened clinical outcome. Adding salmeterol improved FEV1 level.
The study was not designed to evaluate clinical outcomes. Measurement of primary outcome was not available for 24% of patients at 30 months.
ICS therapy decreases inflammation and can attenuate decline in lung function in steroid-naive patients with moderate to severe COPD. Adding LABAs does not enhance these effects.
Primary Funding Source:
Netherlands Organization for Scientific Research, Netherlands Asthma Foundation, GlaxoSmithKline of The Netherlands, University Medical Center Groningen, and Leiden University Medical Center.
Lapperre TS, Snoeck-Stroband JB, Gosman MM, Jansen DF, van Schadewijk A, Thiadens HA, et al. Effect of Fluticasone With and Without Salmeterol on Pulmonary Outcomes in Chronic Obstructive Pulmonary Disease: A Randomized Trial. Ann Intern Med. 2009;151:517–527. doi: 10.7326/0003-4819-151-8-200910200-00004
Effect of Treatment With Fluticasone With and Without Salmeterol on Airway Inflammation and Lung Function in Patients With Chronic Obstructive Pulmonary Disease
Update in Pulmonary and Critical Care Medicine
Annals of Internal Medicine; 151 (8): I-21
Update in General Internal Medicine
Update in Pulmonary and Critical Care Medicine: Evidence Published in 2011
Adding salmeterol to fluticasone did not increase serious asthma events and reduced exacerbations
Annals of Internal Medicine; 165 (10): JC57
Adding salmeterol to fluticasone does not increase serious asthma events or reduce exacerbations in children
Review: In COPD, fluticasone or budesonide increases serious pneumonia but not mortality
Annals of Internal Medicine; 161 (4): JC8
Tiotropium reduced exacerbations more than salmeterol in moderate-to-very severe COPD
Annals of Internal Medicine; 155 (2): JC1-3
Related Point of Care
Annals of Internal Medicine; 154 (7): ITC4-1
Chronic Obstructive Airway Disease
Pulmonary/Critical Care
Chronic Obstructive Airway Disease, Pulmonary/Critical Care.
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