text:
TEST_SUITE(Journal)
{
	static const string logSuffix(".log");

	UNIT_TEST(emptyJournalForNonExistingFile) {
		const Path tempPath(FileUtils::getTempFile() + logSuffix);
		Journal j(tempPath, ProcessID(1));

		assertEquals(0u, j.journalSize());
		assertEquals(tempPath, j.path());
	}

	UNIT_TEST(persistenceCheckOkEmptyJournal) {
		const Path tempPath(FileUtils::getTempFile() + logSuffix);
		Journal j(tempPath, ProcessID(1));

		assertTrue(j.performConsistencyCheck());
	}

	void manuallyReadJournal(UnitTest* unitTest, const string& path, char* dest, uint32_t* size) {
		FILE* file = fopen((path).c_str(), "r+b");
		assertNotNull(file);

		*size = FileUtils::getFileSize(file);

		fread(dest, *size, 1, file);
		fclose(file);
	}

	void manuallyCreateLockFile(const string& path) {
		string lockPath = path + string(".lock");
		FILE* fileHandle = fopen(lockPath.c_str(), "a");
		fclose(fileHandle);
	}

	UNIT_TEST(persistenceCheckOkForValidJournal) {
		const Path targetJournal(FileUtils::getTempFile() + logSuffix);
		const Path originalJournal("test-resources/journals/persistenceCheckOkForValidJournal.log");
		assertTrue(FileUtils::copyFile(originalJournal, targetJournal));

		manuallyCreateLockFile(targetJournal.value);

		Journal j(targetJournal);
		assertTrue(j.performConsistencyCheck());

		char temp[1024] = {0};
		uint32_t tempSize = 0;
		const string expectedJournal("test-resources/journals/persistenceCheckOkForValidJournal_expected.log");
		manuallyReadJournal(unitTest, expectedJournal, temp, &tempSize);

		ByteBuffer bb(1024);
		AutoClosable<FileInputStream>(j.inputStream(0))->readBytes(&bb);
		const char* ptr = bb.ptr();

		assertEquals(tempSize, bb.offset());
		for (uint32_t i = 0; i < tempSize; ++i) {
			char c1 = ptr[i];
			char c2 = temp[i];

			assertEquals(c1, c2);
		}
	}

	UNIT_TEST(persistenceCheckOkForJournal1) {
		const Path targetJournal(FileUtils::getTempFile() + logSuffix);
		const Path originalJournal("test-resources/journals/persistenceCheckOkForJournal1.log");
		assertTrue(FileUtils::copyFile(originalJournal, targetJournal));

		manuallyCreateLockFile(targetJournal.value);

		Journal j(targetJournal);
		assertTrue(j.performConsistencyCheck());

		char temp[1024] = {0};
		uint32_t tempSize = 0;
		const string expectedJournal("test-resources/journals/persistenceCheckOkForJournal1_expected.log");
		manuallyReadJournal(unitTest, expectedJournal, temp, &tempSize);

		ByteBuffer bb(1024);
		AutoClosable<FileInputStream>(j.inputStream(0))->readBytes(&bb);
		const char* ptr = bb.ptr();

		assertEquals(tempSize, bb.offset());
		for (uint32_t i = 0; i < tempSize; ++i) {
			char c1 = ptr[i];
			char c2 = temp[i];

			assertEquals(c1, c2);
		}
	}

	UNIT_TEST(persistenceCheckOkForJournal2) {
		const Path targetJournal(FileUtils::getTempFile() + logSuffix);
		const Path originalJournal("test-resources/journals/persistenceCheckOkForJournal2.log");
		assertTrue(FileUtils::copyFile(originalJournal, targetJournal));

		manuallyCreateLockFile(targetJournal.value);

		Journal j(targetJournal);
		assertTrue(j.performConsistencyCheck());

		char temp[1024] = {0};
		uint32_t tempSize = 0;
		const string expectedJournal("test-resources/journals/persistenceCheckOkForJournal2_expected.log");
		manuallyReadJournal(unitTest, expectedJournal, temp, &tempSize);

		ByteBuffer bb(1024);
		AutoClosable<FileInputStream>(j.inputStream(0))->readBytes(&bb);
		const char* ptr = bb.ptr();

		assertEquals(tempSize, bb.offset());
		for (uint32_t i = 0; i < tempSize; ++i) {
			char c1 = ptr[i];
			char c2 = temp[i];

			assertEquals(c1, c2);
		}
	}

	UNIT_TEST(persistenceCheckOkForJournal3) {
		const Path targetJournal(FileUtils::getTempFile() + logSuffix);
		const Path originalJournal("test-resources/journals/persistenceCheckOkForJournal3.log");
		assertTrue(FileUtils::copyFile(originalJournal, targetJournal));

		manuallyCreateLockFile(targetJournal.value);

		Journal j(targetJournal);
		assertTrue(j.performConsistencyCheck());
		assertEquals(0U, j.journalSize());

		auto const size = FileUtils::getFileSize(targetJournal.value);
		assertEquals(0u, size);
	}
}


text:
Mark Anesh Experienced Legal Professional
Mark Anesh has been working in the legal field for more than 30 years and he has a great expertise in handling professional liability cases. He has represented attorneys, agents, brokers and several other professionals from public sector and municipal liability sectors over the years. A successful legal professional, Mark Anesh is the known as the -lawyers' lawyer- because of his success in all the cases he has chosen to represent over the years. His aggressive stance for the legal cases has earned him the respect and admiration of his colleagues in the legal profession along with preference of clients tangled in difficult legal situations.
Even though Mark Anesh is focused on presenting the cases related to litigation, he has also represented insurers in coverage disputes and declaratory judgment actions. He also offers risk management services for lawyers which include audits, seminars, newsletters, on-line continuing legal education and 1-800 hotlines. The 1800 hotlines owned by Mark Anesh provide legal guidance to professionals from all over the country. The advice provided by Mark Anesh and legal experts working with him has helped many professionals in reducing the claims against them.
Along with being an active legal professional, Mark Anesh also lectures frequently on risk management for attorneys for the New York State and American Bar Associations. He is also an adjunct professor of law at Touro Law Center, an assistant adjunct professor of law at the Hofstra University School of Law. Mark Anesh was also the founding president of Woodbury Jewish Center in Woodbury NY in 1987. The Jewish center started with 12 families and now it has more than 500 families. An experienced and highly respected legal professional, Mark Anesh also provides on-line continuing legal education for the benefit of legal professionals.
Divorce - Positive Side and Benefits
When Is Divorce Advisable

redpajama_set_name: RedPajamaCommonCrawl


Located at the state capital of Mato Grosso, with 131 thousand m2. You will find the biggest shopping center of the state with the national reference of Brimalls shopping building construction, the "Shopping Center Estação Cuiabá". Beside the unquestionable architectural beauty, the ventilated façade was a perfect thermal advantage choice as the average temperature in Cuiabá is 30º during all the year.
We had some issues in this project, for example the curve façade but it didn't stop us to make a good job, also the aluminium friezes installation, that was the architect special requirements, what made him appreciate more the façade.
The system used was the Rediwa Cat 3 with 90x90cm porcelain tiles in 1500m2 of ventilated façade.


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Fantastic laser burst effect using a 40mW green and 100mW red laser. Beam splitting creates amazing, room filling patterns from this one very compact unit. Ideal for projections on walls and ceilings in bars, etc. This easy to use plug & play unit does not require any expensive controllers. A simple multifunction infra-red control, is supplied and will control all the functions.
Operates in standalone mode with built-in microphone or will sequence through its automatic shows list. Supplied with a stand, remote and wall fixings.


Control your frowning to prevent wrinkles. It may seem a little silly, but it's true. When you realize that you are doing it, force yourself to stop. In time, you will break the habit.
Watch your caloric intake in order to slow down your aging. Overeating and obesity are linked with more health problems than can be http://www.skinactives.com/Collagen-Serum.html listed here. Talk with your doctor about how many calories you should be taking in at your age, weight and fitness level and then stick to it.
Learn how to live a full life while you can still visit the next site get around and think about ways to live that same life once you are not so mobile. Very few people can get around when they get older the way that they did when they were young, but if you think about how you can make things happen while you are young enough to do them, you are sure to carry on once you cannot.
Go see your doctor regularly for check ups and get tested when asked. By keeping on top of things, you will be able to catch health issues early on and do something about it right away. The sooner you address your concerns, the sooner you can begin to eliminate or treat the problem.


I work with CIOs, CEOs, and the leaders of a company's major technology initiatives, assisting them with process consulting, project assurance, IT strategy, technology selections and technology assessments.
In our technology consulting practice, we help clients maximize the value of their technology investments to achieve their goals while minimizing risk. For many of these clients, their biggest challenge is dedicating sufficient staff resources to significant tech initiatives. That's why it's my role to advise them on all information technology matters.
I'm proud of how I've partnered with several small tech companies early in my career to oversee their expansion throughout the United States. As a result of client growth like this, we've been able to fuel the growth of Plante Moran's national management consulting practice with a specialization in IT and operations consulting.
When I'm not counseling external clients, I spend a lot of time thinking about the staff on my team. I try to help people advance in their own careers by pairing them with the right assignments that also allow for work-life balance. They count on me to advocate for them. Plante Moran's work-life balance is important to me because I have a wife and three kids. I love spending time with them, planning vacations, mountain biking, or simply relaxing.
A couple of times a year, I speak at events such as the Public Technology Institute Conference, International City/County Management Association, and others on issues of contract management, data analytics, and technology due diligence. I have a B.S. in computer science from the University of Michigan–Dearborn and an M.B.A. from U of M's Ross School of Business.
My dad used to own a construction company, so I spent two summers in college doing manual labor for him. I worked with the roofing crew on the construction of new houses.


The American Cancer Society now recommends that colon cancer screening begin at age 45 for people at average risk.
Our highly skilled medical and administrative staff is committed to your well-being, in an environment designed to provide comfort and convenience for our patients and their families.
We treat a variety of conditions using the most up-to-date technologies and treatments to ensure the best treatment possible for your digestive health.
The physicians and staff of Asheville Gastroenterology Associates are committed to providing the highest quality and most comprehensive healthcare in the field of digestive diseases. AGA has now grown to 17 Board Certified Gastroenterologist and 8 Advanced Practitioners specializing in the prevention, diagnosis, and treatment of gastrointestinal conditions in adults.
AGA has over 20 years of academic and pharmaceutical industry research.


Stagecoach Walton on Thames is head office to over 600 Stagecoaches.
Stagecoach is a performing Arts School which offers three hours of drama, singing and dancing in one session for children aged over 6 years, with a shorter 90 minute session for our younger members.
Further Stages class is an extra session for those aged 15+ who wish to further develop their Musical Theatre Skills.
If you are looking for a drama school for your child with classes in dancing, drama and singing in Walton on Thames then please have a look at our selection of classes.
Our Boys Ballet classes run each Monday evening in Walton on Thames.
Do you have a son aged between 4 and 18 years?
Would he like to learn ballet with other like-minded boys?
Would ballet interest him but not if it were with girls?
We run classes each Monday.


text:
Schöferhof ist eine Ortschaft in der Gemeinde Gutau im Bezirk Freistadt, Oberösterreich.

Die Ortschaft befindet sich südöstlich von Freistadt, teils im Einzugsgebiet der Waldaist, die auch die Südgrenze des Gemeindegebietes darstellt, und teils im Einzugsgebiet der Feldaist, die etwas weiter westlich des Gemeindegebietes liegt. Am  zählte die Ortschaft  Einwohner.

Einzelnachweise

Gutau
Ort im Bezirk Freistadt

redpajama_set_name: RedPajamaWikipedia


text:
Olympic dreams continue at Harvard
20 February, 2019 in China, #MyRugbyMoment, Womens Rugby by Asia Rugby
For one Chinese girl, an Olympic dream continues at Harvard.
Originally from Shanghai, Sofie Fella is studying psychology and economics having moved to America, but continues to impress in her short rugby career.
She plays Varsity D1 Rugby at Harvard, having only started playing rugby 'for fun' in high school.
"I never thought about applying to Harvard until the beginning of my senior year and even then I did it without thinking I would get in," said Fella.
"I am extremely grateful to study here because it's a great place to balance both academics and rugby.
"The team, coaching staff, teachers, and people you meet here are really supportive and caring, which helps a lot when moving to the US all the way from Shanghai."
Fella, who has a German Dad and Chinese Mum, started playing rugby in high school and went to a few camps in America.
She was selected to compete as part of an all-star team in her first tournament in the US and spent time traveling between China and America to compete in tournaments like the Las Vegas Invitational.
"During my summers I would train with residency programs such as the American Rugby Pro Training Center and the Atavus Academy 7s," added Fella.
"I found that playing with older players everyday during the summer really helped me improve.
"I also competed with the Germany U18 7s team at the European Championships in Andorra which was a great experience.
"Now I play at the collegiate level and I love it. Before rugby, I would bounce from hobby to hobby, never sticking with one. It has played a huge role in my life, giving me something to love and be motivated for.
"The sport has given me the ability to set goals and achieve them as well as set dreams for the future. I'm super grateful to have found this sport and I love everything about it."
Having fallen in love with the sport, Fella continues her rugby journey at Harvard and has always 'dreamed of playing rugby in the Olympics or the World Series'.
Having played with the Germany U18s 7s team and tried out for the Chinese 7s team, she is still deciding which country's pathway to step into.
"For now, however, I am focusing just on improving and being the best rugby player I can be and I'll let the future play out and see what happens."
And with the first-ever Rugby World Cup taking place in the continent she grew up in, the opportunities for Asia are huge in 2019.
"Having a Rugby World Cup in Asia is a huge step in growing rugby into a world sport," explained Fella.
"Coming from an Asian country myself, I know what it's like to not be able to find club teams or high level training opportunities close to me.
"I'd have to fly to the US to compete with teams there or go to summer programs there.
"Our high school season only lasted two months and I went looking for more opportunities to play high level rugby throughout the year, but didn't find many options.
"Hosting an event like the World Cup will help increase the interest in the sport in Asia and hopefully generate more supporters and more players."
Filed Under: China, #MyRugbyMoment, Womens Rugby Tagged: China


text:
12.05.2019 by 4:33pm
Tags: Holualoa Companies, Richard Kauffman
From Commercial Executive Magazine
Tucson, Arizona – Richard B. Kauffman has been promoted to Chief Executive Officer of Holualoa Companies effective December 1, 2019.
I. Michael Kasser will continue to guide Holualoa as Founder and Chairman of the company. "Rick's leadership has been an integral part of Holualoa's success, and his becoming CEO is a natural step forward for the company," Kasser said.
Kauffman, who has been with Holualoa since 2000 in various finance and operational roles, previously served as the company's Chief Financial Officer.
"I am honored to work with Holualoa's skilled team of over 30 professionals and particularly with the partners on the company's executive team, including Aroon Chinai (Chief Investment Officer), Stan Shafer (Chief Operating Officer) and Lani Baker (Vice President of Finance)," Kauffman said.
Holualoa was founded by Kasser in Hawaii 35 years ago. The company expanded to the Southwest in the Resolution Trust Corporation days with a Tucson office. The company continued to grow by opening offices in Phoenix, Arizona and Santa Monica, California. Further expansion led Holualoa to partnerships in Washington, DC and Paris, France.
11.26.2019 11.26.2019 by 9:33am
Click here to download a PDF with coverage of Holualoa's leaders and properties in AZRE Magazine.
09.11.2019 by 11:15am
Tags: Forbes Office, Holualoa Companies
A Tucson office property vacated in 2016 will soon undergo a significant revitalization effort to make it more desirable for businesses and better-suited for multitenant use.
The property, located at 2202 Forbes Blvd. in Tucson, is part of the larger Broadbent Interstate Center, which first took shape in the 1980s. The Forbes office building is a 58,000-square-foot back office building recently owned by Carondelet Healthcare. When Carondelet was purchased by Tenet Healthcare in 2016, Tenet moved its operations out of the building.
Holualoa Companies officially acquired the property on Sept. 6, and plans a $4 million renovation to transform the space for a wide range of medical, office and other tenants to meet rising demand across the region. The property will feature a market-leading parking ratio of 9 spaces per 1,000 square feet of rentable space.
Holualoa Companies' Vice President of Finance Lani Baker said the property was particularly desirable because of its well-established location, its close proximity to Interstate 10 and the University of Arizona.
"There's a significant need for quality office space in this area, so transforming this vacant property into desirable office space helps address the needs of this growing part of Tucson," she said. "We have a number of companies that have already expressed interest in putting down roots at Forbes, and adding more parking spaces, upgrading building systems and otherwise enhancing its amenities will only increase its desirability."
Holualoa Companies already has a large presence throughout Tucson, including extensive office, industrial and multifamily properties. The company's planned $4,090,000 investment in the property will finance additional parking areas, leasing efforts and additional accommodations needed to make the property ideal for multi-tenant use.
08.26.2019 08.26.2019 by 11:21am
Tags: Gateway at Tucson, Holualoa Companies
A Tucson multifamily residential complex is about to receive a $10 million renovation to transform it into a premier apartment community.
Gateway at Tucson Apartments, a 188-unit complex located at 2800 W. Broadway Road, will be completely renovated over the course of the next year. The complex, built in 2005 to serve college students, will be reintroduced to the market as a 272-unit multifamily community with exceptional amenities and a variety of floor plans available.
Holualoa Companies purchased Gateway in November 2018 with the intention of transforming it into a more dynamic and inviting residential community to help meet a surge in demand for multifamily in the Tucson marketplace. Multifamily occupancy in the Tucson market reached 95 percent in 2019, which has led to an increase in rents year-over-year of almost 8 percent.
Lani Baker, Vice President – Finance of Holualoa Companies, said the property was an ideal opportunity for renovation because of its location near Downtown Tucson.
"We look forward to transforming this property into a community that is truly inviting for residents wanting to live in this bustling area of Tucson," Baker said. "Because of the significant need in the Tucson market for properties such as this, we're confident that the project will be successful and will be a welcoming living environment for residents."
Gateway will remain open for current residents during construction.
Holualoa Companies plans to split each of the existing 84 four‐bedroom units at Gateway — designed for groups of students — into one‐bedroom and two‐bedroom units, renovate all unit interiors, and remedy a significant amount of deferred maintenance as part of the renovation.
Holualoa Companies has an extensive experience with multifamily assets in Arizona, having acquired more than 5,700 units. The company also has extensive office and industrial holdings in Tucson.
08.22.2019 by 8:13am
Tags: Camelback Collective, Holualoa Companies, Stifel
One of the country's premier investment firms is moving its Phoenix office to a premier location in the Camelback Corridor's newest office project. Stifel, Nicolaus & Company, Incorporated ("Stifel") is a full-service wealth management and investment banking firm established in 1890. It is the primary broker-dealer subsidiary of Stifel Financial Corp., a diversified financial services holding company that conducts its business through several wholly-owned subsidiaries.
Tags: Holualoa Companies, Scottsdale, Scottsdale North Marketplace
A prominent north Scottsdale retail center has new ownership as a result of a $16 million sale that closed last week. Scottsdale North Marketplace, a 68,522-square-foot retail center located at Scottsdale Road and Lone Mountain Road, was purchased by a joint venture between Holualoa Companies and Epic Real Estate Partners in a $16 million transaction.
Tags: Creighton University, Park Central
PHOENIX, ARIZ. – It's about to get busy at Park Central in midtown Phoenix, as construction of Creighton University's nearly $100 million health sciences campus gets underway on July 8.Plaza Companies is the developer, and Okland Construction will be the general contractor for the first phase of the Creighton University building. Butler Design Group will serve as the architect, and the conceptual and tenant design and improvement architect is RDG Planning & Design….
Tags: Holualoa Companies, Park Central
Midtown Phoenix is no longer a canyon of far-from-full office towers built more than three decades ago.
The area that businesses moved away from in the late 1990s is now drawing start-ups and big companies that want to be near light rail, new restaurants, apartments, redeveloped buildings and revived historic neighborhoods.
Tags: AC Marriott, Camelback Collective, Holualoa Companies
A new AC Hotels by Marriott has opened in Phoenix's upscale Biltmore area, and it looks to cater to both business and leisure travelers.
The 160-room AC Hotel Phoenix Biltmore is part of the Marriott International (Nasdaq: MAR) brand that has heavy European influences. The property, at 2811 E. Camelback Road, had a soft opening in October and held a grand opening event on Nov. 8.


text:
TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis
Jiwei Hou, Tan Ma, Honghui Cao, Yabing Chen, Cong Wang, Xiang Chen, Xiang Zou, Xiaodong Han
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease of unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR-MSCs) and tumor necrosis factor-α (TNF-α) play important roles in the development of pulmonary fibrosis. However, the underlying connections between LR-MSCs and TNF-α in the pathogenesis of pulmonary fibrosis are still elusive. In this study, we found that the pro-inflammatory cytokine TNF-α and the transcription factor nuclear factor kappa B (NF-κB) p65 subunit were both upregulated in bleomycin-induced fibrotic lung tissue. In addition, we discovered that TNF-α promotes myofibroblast differentiation of LR-MSCs through activating NF-κB signaling. Interestingly, we also found that TNF-α promotes the expression of β-catenin. Moreover, we demonstrated that suppression of the NF-κB signaling could attenuate myofibroblast differentiation of LR-MSCs and bleomycin-induced pulmonary fibrosis which were accompanied with decreased expression of β-catenin. Our data implicates that inhibition of the NF-κB signaling pathway may provide a therapeutic strategy for pulmonary fibrosis, a disease that warrants more effective treatment approaches.
Journal of Cellular Physiology
https://doi.org/10.1002/jcp.26112
idiopathic pulmonary fibrosis (IPF)
lung resident mesenchymal stem cells (LR-MSCs)
myofibroblast differentiation
NF-κB signaling
tumor necrosis factor-α (TNF-α)
10.1002/jcp.26112
Hou, J., Ma, T., Cao, H., Chen, Y., Wang, C., Chen, X., Zou, X., & Han, X. (2018). TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis. Journal of Cellular Physiology, 233(3), 2409-2419. https://doi.org/10.1002/jcp.26112
Hou, Jiwei ; Ma, Tan ; Cao, Honghui ; Chen, Yabing ; Wang, Cong ; Chen, Xiang ; Zou, Xiang ; Han, Xiaodong. / TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis. In: Journal of Cellular Physiology. 2018 ; Vol. 233, No. 3. pp. 2409-2419.
@article{896b9171e6284ffdb13bfe149bfdf540,
title = "TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis",
abstract = "Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease of unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR-MSCs) and tumor necrosis factor-α (TNF-α) play important roles in the development of pulmonary fibrosis. However, the underlying connections between LR-MSCs and TNF-α in the pathogenesis of pulmonary fibrosis are still elusive. In this study, we found that the pro-inflammatory cytokine TNF-α and the transcription factor nuclear factor kappa B (NF-κB) p65 subunit were both upregulated in bleomycin-induced fibrotic lung tissue. In addition, we discovered that TNF-α promotes myofibroblast differentiation of LR-MSCs through activating NF-κB signaling. Interestingly, we also found that TNF-α promotes the expression of β-catenin. Moreover, we demonstrated that suppression of the NF-κB signaling could attenuate myofibroblast differentiation of LR-MSCs and bleomycin-induced pulmonary fibrosis which were accompanied with decreased expression of β-catenin. Our data implicates that inhibition of the NF-κB signaling pathway may provide a therapeutic strategy for pulmonary fibrosis, a disease that warrants more effective treatment approaches.",
keywords = "idiopathic pulmonary fibrosis (IPF), lung resident mesenchymal stem cells (LR-MSCs), myofibroblast differentiation, NF-κB signaling, tumor necrosis factor-α (TNF-α)",
author = "Jiwei Hou and Tan Ma and Honghui Cao and Yabing Chen and Cong Wang and Xiang Chen and Xiang Zou and Xiaodong Han",
doi = "10.1002/jcp.26112",
journal = "Journal of Cellular Physiology",
publisher = "Wiley-Liss Inc.",
Hou, J, Ma, T, Cao, H, Chen, Y, Wang, C, Chen, X, Zou, X & Han, X 2018, 'TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis', Journal of Cellular Physiology, vol. 233, no. 3, pp. 2409-2419. https://doi.org/10.1002/jcp.26112
TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis. / Hou, Jiwei; Ma, Tan; Cao, Honghui; Chen, Yabing; Wang, Cong; Chen, Xiang; Zou, Xiang; Han, Xiaodong.
In: Journal of Cellular Physiology, Vol. 233, No. 3, 01.03.2018, p. 2409-2419.
T1 - TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis
AU - Hou, Jiwei
AU - Ma, Tan
AU - Cao, Honghui
AU - Chen, Yabing
AU - Wang, Cong
AU - Chen, Xiang
AU - Zou, Xiang
AU - Han, Xiaodong
N2 - Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease of unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR-MSCs) and tumor necrosis factor-α (TNF-α) play important roles in the development of pulmonary fibrosis. However, the underlying connections between LR-MSCs and TNF-α in the pathogenesis of pulmonary fibrosis are still elusive. In this study, we found that the pro-inflammatory cytokine TNF-α and the transcription factor nuclear factor kappa B (NF-κB) p65 subunit were both upregulated in bleomycin-induced fibrotic lung tissue. In addition, we discovered that TNF-α promotes myofibroblast differentiation of LR-MSCs through activating NF-κB signaling. Interestingly, we also found that TNF-α promotes the expression of β-catenin. Moreover, we demonstrated that suppression of the NF-κB signaling could attenuate myofibroblast differentiation of LR-MSCs and bleomycin-induced pulmonary fibrosis which were accompanied with decreased expression of β-catenin. Our data implicates that inhibition of the NF-κB signaling pathway may provide a therapeutic strategy for pulmonary fibrosis, a disease that warrants more effective treatment approaches.
AB - Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease of unknown cause. It has been reported that both lung resident mesenchymal stem cells (LR-MSCs) and tumor necrosis factor-α (TNF-α) play important roles in the development of pulmonary fibrosis. However, the underlying connections between LR-MSCs and TNF-α in the pathogenesis of pulmonary fibrosis are still elusive. In this study, we found that the pro-inflammatory cytokine TNF-α and the transcription factor nuclear factor kappa B (NF-κB) p65 subunit were both upregulated in bleomycin-induced fibrotic lung tissue. In addition, we discovered that TNF-α promotes myofibroblast differentiation of LR-MSCs through activating NF-κB signaling. Interestingly, we also found that TNF-α promotes the expression of β-catenin. Moreover, we demonstrated that suppression of the NF-κB signaling could attenuate myofibroblast differentiation of LR-MSCs and bleomycin-induced pulmonary fibrosis which were accompanied with decreased expression of β-catenin. Our data implicates that inhibition of the NF-κB signaling pathway may provide a therapeutic strategy for pulmonary fibrosis, a disease that warrants more effective treatment approaches.
KW - idiopathic pulmonary fibrosis (IPF)
KW - lung resident mesenchymal stem cells (LR-MSCs)
KW - myofibroblast differentiation
KW - NF-κB signaling
KW - tumor necrosis factor-α (TNF-α)
U2 - 10.1002/jcp.26112
DO - 10.1002/jcp.26112
JO - Journal of Cellular Physiology
JF - Journal of Cellular Physiology
Hou J, Ma T, Cao H, Chen Y, Wang C, Chen X et al. TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis. Journal of Cellular Physiology. 2018 Mar 1;233(3):2409-2419. https://doi.org/10.1002/jcp.26112


Hello!Today I pass IBM Collaboration Solutions exam with 951/1000 points.I have the same question like this material. I haven't notice any new question. The sims are EIGRP, ACL and VTP.Thanks Good luck to all!
today i have passed IBM Collaboration Solutions got 986 score. thiz dums is still valid.


text:
Brie Larson >
Brie Larson's fame fears
By Bang Showbiz in Lifestyle / Showbiz on 05 March 2019
Follow Brie Larson
Brie Larson admits she wasn't sure if she was would take on the role of 'Captain Marvel' because she is a ''super introvert'' and was worried how it would affect her ''anonymity''.
Brie Larson wasn't sure if she was going to take on the role of 'Captain Marvel' because she was worried about her ''anonymity''.
The 29-year-old actress only knew too well how her role in the Marvel movie would shoot her to international fame and she admits she had to carefully consider taking on the job as she is a ''super introvert''.
She said: ''Marvel was very patient with me. They understand what taking something like this on means. My anonymity has always been super important to me, not just because I'm a super introvert - that's how I'm able to disappear into other characters.''
However, Brie is glad she signed up for the movie and she wants the character to inspire girls and young women to be strong individuals.
She told ABC News: ''For it to finally come out and to get these little glimmers of seeing young girls excited about it, it's everything to me. I didn't make this movie for myself, I made it for them.''
Meanwhile, the Hollywood actress previously confessed she is finding the new attention she is currently receiving is ''scary''.
She said: ''It definitely is scary to think of people paying attention to me. I'm not gonna act super-strong when I've been kind of freaking out seeing how quickly my numbers on Instagram have been going up since 'Avengers: Infinity War' came out ... I've been sort of like, 'Oh God, I did not think about that. Um, like why are people paying attention to me?' I really just feel the same. I do feel like just a person. And so it's a weird feeling when people on the outside view you differently.''
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text:
USS Morris (DD-271) was a  built for the United States Navy during World War I.

Description
The Clemson class was a repeat of the preceding  although more fuel capacity was added. The ships displaced  at standard load and  at deep load. They had an overall length of , a beam of  and a draught of . They had a crew of 6 officers and 108 enlisted men.

Performance differed radically between the ships of the class, often due to poor workmanship. The Clemson class was powered by two steam turbines, each driving one propeller shaft, using steam provided by four water-tube boilers. The turbines were designed to produce a total of  intended to reach a speed of . The ships carried a maximum of  of fuel oil which was intended gave them a range of  at .

The ships were armed with four 4-inch (102 mm) guns in single mounts and were fitted with two  1-pounder guns for anti-aircraft defense. In many ships a shortage of 1-pounders caused them to be replaced by 3-inch (76 mm) guns. Their primary weapon, though, was their torpedo battery of a dozen 21 inch (533 mm) torpedo tubes in four triple mounts. They also carried a pair of depth charge rails. A "Y-gun" depth charge thrower was added to many ships.

Construction and career
Morris, named for Charles Morris, was laid down 20 July 1918 by the Fore River Plant, Bethlehem Shipbuilding Corporation, Squantum, Massachusetts; launched 12 April 1919; sponsored by Mrs. George E. Roosevelt, great-granddaughter of Commodore Charles Morris; and commissioned 21 July 1919.

On 26 August 1919 Morris sailed for European waters. A month later she passed through the Strait of Gibraltar and continued on to Split, Croatia (then Yugoslavia). There she joined the Adriatic Detachment which was then performing quasi-political and diplomatic duties in the void caused by the breakup of the Austro-Hungarian Empire. She returned to New York 21 May 1920 and operated briefly on the east coast before sailing for San Diego, California. Steaming via the Panama Canal she arrived at San Diego 7 September and for the next 9 months cruised south for brief patrols off the politically unstable countries of Nicaragua and Mexico.

She decommissioned at San Diego 15 June 1922 and entered the Reserve Fleet. Struck from the Naval Vessel Register 19 May 1936, she was sold to the Schiavone Bonomo Corporation of New York City 29 September 1936.

Notes

References

External links

http://www.navsource.org/archives/05/271.htm

Clemson-class destroyers
Ships built in Quincy, Massachusetts
1919 ships


text:
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text:
Грег Лий Хенри () (роден на 6 май 1952 г.) е американски актьор.

Частична филмография

Филми
 1983: "Белязаният"
 1984: "Дубльорката"
 1992: "Пристъп на безумие"
 1998: "Стар Трек: Бунтът"
 1999: "Разплата"
 2002: "Фатална жена"
 2002: "Балистик"
 2003: "Чистилището"
 2003: "Грях"
 2006: "Плужекът"
 2006: "Полет 93"
 2006: "Черната далия"
 2014: "Пазителите на Галактиката"
 2016: "Джейсън Борн"
 2017: "Пазителите на Галактиката: Втора част"

Телевизия
 1976–1977: "Богат, беден: Втора книга"
 1985: "Съдружници по неволя"
 1985–1996: "Убийство по сценарий"
 1987–1995: "Матлок"
 1987: "Магнум"
 1988–1994: "Законът на Ел Ей"
 1989: "Джейк и дебелака"
 1994: "Уокър, тексаският рейнджър"
 1995: "Военна прокуратура"
 1995: "Болница Чикаго хоуп"
 1996: "Хамелеонът"
 2001: "От местопрестъплението"
 2002: "Светулка"
 2002: "Бумтаун"
 2002: "ЦРУ"
 2003: "Стар Трек: Ентърпрайз"
 2003: "Съдия Ейми"
 2003: "24"
 2004: "ФБР инструктор"
 2006–2010: "От местопрестъплението: Маями"
 2005–2007: "Момичетата Гилмор"
 2008: "Спешно отделение"
 2008: "Менталистът"
 2009: "Звярът"
 2009: "Къща за кукли"
 2009: "Мръсно синьо"
 2009: "Криминални уравнения"
 2009: "Касъл"
 2009: "Клуб Веселие"
 2010: "Анатомията на Грей"
 2010: "Добрите момчета"
 2010: "Медиум"
 2011: "Законът на Хари"
 2011: "Слънчасали"
 2009–2011: "Увиснал"
 2011: "Извън играта"
 2012: "Военни престъпления: Лос Анджелис"
 2011: "Честни измамници"
 2011–2012: "Кралете на бягството"
 2012: "Престъпления от класа"
 2012–2017: "Скандал"
 2013–2014: "Убийството"
 2014–2016: "Ад на колела"
 2014–2015: "Последователите"
 2015–2016: "От местопрестъплението: Кибер атаки"
 2016: "Лекарите от Чикаго"
 2016: "Момичетата Гилмор: Една година от живота"
 2017: "Супергърл"

Източници

Външни препратки

Американски актьори и актриси


Discussion in 'Photojournalism, Candids and Street Photography' started by 4labs, Apr 21, 2005.
having no kids of my own(yet) I love spending time with my siblings kids. Both my brother and sister have two girls. Julia and Jillian are just a few montsh apart in age but you can tell from the pictures that they are very different.
Looks like that Jillian is a real go-getter on the field. Julia on the other hand appears to be much more reserved (that was always me!). You've not only captured great shots, but obviously you know your subjects well enough to catch their personality as well. I'm sure their parents will love these frozen memories. BTW, i just love shots of kids....mine or anyones! Good job.
Very nice image. The tongue in cheek on #2 is a classic. Good captures.
I like number one the best as well. Exposure was probably tough that day, but you did a great job exposing her face even with the high contrast from the sun. I also like the action of that shot!
Nice set of action shots!!
Thnxs for taking the time to look everyone. DavidM You sure were right about the harsh sun. Getting the exposure was more a matter of having a good camera than me knowing how to get it. I have spent hours reading Ron's ebook and studying histograms and all I get is a headache.
Lovely kids! Just love the lighting and action in number 2, they are all great! Stick with Ron's book - he's the best there is!
Nice shots, especially given the harsh lighting condition. Adorable and great fun. First two are best.
FYI, this is part of the reason why I decided to upgrade to DSLR (from a prosumer compact).
Thnxs everyone once again it is great to find a place where all photography is welcomed and not just fine art. Man-Fai I know what you mean I started with the a Coolpix and now I will go broke from this hobby..
second was with the Bigma. I think I am going to haev to shell out some bucks for a long Nikon lens..


text:
Theater Accidentally Plays Horror Movie Trailer Before Peter Rabbit, Families Run Out Screaming
Matt Novak
The upcoming horror movie Hereditary is being touted as one of the scariest films of the year. So when a theater outside Perth, Australia accidentally played the trailer before a screening of Peter Rabbit, you can guess what happened.
"It was dreadful," one parent at the screening told the local news website WA Today. "Very quickly you could tell this was not a kid's film. Parents were yelling at the projectionist to stop, covering their kids' eyes and ears."
The screening was on Wednesday, a national holiday in Australia known as Anzac Day, where most people get the day off. But some families who had chosen to go to the movies got way more than they bargained for. One horrified witness explained how other parents, "fled the cinema with their kids in tow."
Understandably, the movie theater wanted to make things right. The theater, Event Cinemas in Innaloo, released a statement:
As soon as the staff onsite were made aware of the situation yesterday, the trailers were taken off-screen immediately and all patrons were given complimentary tickets as a gesture of goodwill.
The only problem? The movie theater even messed up their apology. The free movie passes reportedly had an expiration date of April 25, 2018, the same day as the screening.
"We had been told they were valid for a month but they were out of date," one parent told WA Today. But the theater insists that the free tickets will be honored until April 25, 2019, no matter what's printed on the piece of paper.
For comparison's sake, here's the trailer for Hereditary...
...and here's the trailer for Peter Rabbit:
So you can see why both parents and kids might have been a little disturbed on their day off.
Hereditary, which actually looks pretty good in this humble blogger's opinion, hits theaters June 8th. You can read the io9 review here. Peter Rabbit is in theaters now.
[WA Today and Pedestrian.tv]
Matt Novak is the editor of Gizmodo's Paleofuture blog
Zhesty
Am I terrible for finding this funny?


text:
Home> Review> A Crisis of Legitimacy
A Crisis of Legitimacy
Posted by John Heathershaw
On the tenth anniversary of the publication of his book Post-conflict Tajikistan: the politics of peacebuilding and the emergence of legitimate order, John Heathershaw uses a tenouous link to Central Asia to reflect on how its central concept of legitimacy pertains to the Brexit crisis engulfing the UK
Over three years since Britain voted to leave the European Union in 2016, arguments have intensified and political turmoil has increased. As I write, another turbulent week in parliament has left the country more divided than ever in my lifetime.
Many who voted leave simply cannot understand why we haven't left yet and blame truculent Remainers for blocking Brexit, the democratic will of the people. Many who voted remain simply see the chaos as indicating the stupidity of this choice and so damaging that it cannot be allowed to stand. Both sides question the legitimacy of the other's position.
As a former civil servant and political scientist (whom you may not be surprised to know voted remain), I recognise both these claims of legitimacy as being in turn procedural and substantive. For leavers, Brexit is procedurally legitimate – that is the process was governed by fair rules and democratic consent – because it was passed by popular vote. For Remainers, staying in the EU is substantively legitimate – that is in terms of its outcome– because the economic and political benefits of staying in are far greater than leaving.
But both of these claims to legitimacy are dubious.
First, leavers who argue that the choice made was procedurally legitimate and the losers must simply respect the result simply misunderstand the democratic process. Public votes are not mere shows of hands. Democracy and voting only work when they are constituted by clear rules which enable the will of majorities, protect minorities from an unlimited interpretation of that will, and are enacted by responsible leaders. In 2015, by agreeing to a straight in/out referendum, David Cameron committed vandalism against democracy by putting two incomparable choices to the public.
'Remain' was clear as the terms of Britain's membership were established over 40 years and thousands of pages of international treaties. However, 'Leave' was left entirely undefined. It could be anything from Norway-style single market membership to leaving without a deal. For more than three years the Conservative government which has been responsible for defining 'leave' has simply been unable to generate enough support behind any one of the many possible versions of Brexit. The continuing rancour among Tories today can be directly tied to Cameron's fateful decision in 2015.
To highlight quite how procedurally illegitimate the Brexit referendum question was let's consider what would happen if a similar approach were taken to Westminster elections. Voters would simply be given the choice between their MP or 'someone else'. In such circumstances, with MPs unpopular and the pros and cons of the alternative left to the imagination, 'someone else' may win. However, how would the electoral commission or returning officer decide on this 'someone else'? If elections were held like that, parliament would never work; that is why 'none of the above' is not an acceptable outcome in a representative democracy. The problem with the referendum was not the outcome but the question.
Political scientists know that referendums are particularly prone to this kind of problem if their question is not well-defined. In California, voters are asked to read detailed descriptions several pages long of the proposal made to them in the voting booth before making their choice on a specific question of policy. In Ireland, the constitution requires that a law is passed to specify in detail the outcomes which voters choose from. Most countries would also require a qualified majority to pass a constitutional change; in the UK, for example, it would have been sensible for majorities to be required in all three nations with devolved powers as well as the country as a whole. David Cameron's government did none of these things, making the Brexit vote itself illegitimate and plunging the UK into the political crisis through which we now live.
Second, however, the argument of ardent Remainers that it is substantively legitimate to stay in the EU because of its better outcomes for Britain is also wrong. All sensible economists agree that Britain will be poorer without frictionless trade with its closest neighbours with whom its economic integration is far-reaching. International relations specialists like myself almost all agree that Britain's international influence will go down dramatically now it cannot work through the 'force multiplier' of the EU. Most also recognise that it is perfectly legitimate for national democracy in an era of globalization to be subject to internationally-agreed rules, rather than this being an unconscionable violation of sovereignty.
However, these arguments, while valid factual points, are dubious as claims for the substantive legitimacy of Remain. Outcomes are not simply legitimate because they are better in objective and materials terms – that would be the legitimate standard to which a technocrat or perhaps a dictator is held. In a democracy, substantive legitimacy is achieved by an outcome which is in consistent with the political beliefs of the people. As the German sociologist Max Weber identified, these beliefs are shaped by tradition and charisma, as well as by rational argument. Notwithstanding procedural illegitimacy, the substantive political belief of a small majority of voting Britons with respect to the EU was clearly to leave.
The great tragedy of Brexit is that Leave and Remain each have valid claims to legitimacy which talk past one another and which, as time goes on, are less inclined to compromise. A substantively legitimate compromise could be a Norway-style deal or other outcome where the UK leaves but remains close to the EU. A procedurally legitimate compromise may be that second referendum between two clear choices. It is certainly possible to leave the EU democratically and with minimal damage, but the UK since 2016 has singularly failed to do so due, primarily to the procedural illegitimacy of the referendum it held.
The importance of legitimacy to politics can hardly be overstated. Without legitimate authority, rules and beliefs politics easily breaks down into violence. Legitimacy, as the political theorist David Beetham argues, is the yeast by which political order is baked. Ten years ago, my book on the civil war in Tajikistan, showed how the war broke out after a crisis of legitimacy with the end of the Soviet Union and was finally ended by a government which was able to deliver substantive legitimacy in accordance with a population which was prepared to surrender freedom for an authoritarian peace.
The crisis in Britain is thankfully less severe and the institutional context much stronger. But without a compromise Brexit or a second referendum the UK itself risks illegitimacy, beckoning Scottish independence, a potential return to violence in Ireland, and increased social and political division across the UK.
An autumn election is likely to return a hung parliament with yet more uncertainty and rancour. A small Conservative majority or a Tory-led coalition which took Britain out without a deal, or even with a warmed-up version of the deal negotiated by May, would face prolonged negotiation with the EU which would put the UK at risk. Even a Labour majority or a 'Remain coalition' would face a legitimacy crisis in enacting a second referendum or a 'soft Brexit'.
In politics, legitimacy is the prerequisite for peaceful change. In the UK it has been foolishly taken for granted. The goal of responsible politicians today, whether Leavers or Remainers, should not be the best outcome but a legitimate one.
[Revised: 8 September, 2019]
A winter general election on 12 December, in fact led to a healthy Conservative majority and ensured the UK would leave the EU at the end of January, 2020. The procedural illegitimacy of the process remains, however, and will continue to divide British politics, probably for decades.
[19 December, 2019]
Posted in Review.
ESCAS 2019: thank you!
Extradition in disguise: the 'deportation' and refoulement of Central Asian political exiles from Russia


The founder and owner of Imperium Productions, Josh enjoys taking projects through every stage of development - from ideas and scripting, to shooting and post, to marketing the final product. With a background in both broadcast and corporate, Josh produces television commercials, documentaries, short films, music videos, and corporate videos. He has worked with numerous celebrities and sports figures, and for clients such as the NBA, Discovery, Food Network, the NFLPA, Coca-Cola, Mercedes-Benz, Ashley Furniture and many more. He has traveled to over 25 countries and shot in Europe, Japan, India, Nepal, Canada and the Caribbean. Josh is also a PADI and SSI Advanced SCUBA diver with experience filming underwater in both controlled and open-water environments.
Grace manages many of Imperium Productions' bookings and client relations. An experienced production manager, she has been a large part of our success and growth in the past few years. Grace's talents allow the rest of us to focus more on the creative, while she manages the necessities of scheduling, organizing and accounting.
Specialties: Scheduling, Organizing, Accounting, and keeping our heads on straight!
A specialist in RED cameras, Patrick is passionate about visual story telling using the medium of motion pictures. He has traveled across the US on productions and has contributed to numerous feature films. "If you are going to tell a story, do so with the best possible look to enhance and not distract from the story. The line is becoming blurred between, TV Shows, Movies and Commercials. All offer a fun place to create and play."
Beginning with short student films in 2008 Westley has found the sound department a natural home on set. With a background in recording and mixing for musicians, recording audio on set was a welcome transition. He has worked on numerous national TV, reality shows, commercial and corporate productions.
Specialties: Production Sound Mixing, Sound Design, Audio Post-production, Recording, Pro Tools, Logic Studio, DaVinci Resolve, Final Cut Pro 7/X, Color-grading.
Journeying all the way from Tokyo and fueled by constant coffee, Kenji radiates energy that brings every project he works on to life! Skilled at intricate storytelling and design, Kenji approaches every project with fresh perspective, bringing the production elements to a point of final impact and emotion before they head out the door. He's created title sequences, television series, short films, and company branding, all while passing on the knowledge of project organization, software integration, and achievement of vision for the final product.


Experience life on a farm at this unique Northern Panhandle getaway.
The owners of Barn With Inn at Highland Springs Farm have it right. Harry Sanford and Chatman Neely believe, "you have to disengage to engage." So they've created a sanctuary outside Wellsburg in the Northern Panhandle where you can do just that, in one of the most unexpected places: a loft above a working barn.
You won't find a bellhop ready to gather your luggage and deliver it to your room. Instead, you'll be greeted by Cooper,their director of public relations—a free-range pot bellied pig. If you are lucky, you might catch Max the rooster riding on his back. And once the seven dogs announce your arrival, Martha the donkey and Jasper and Granite, the farm's two burros, will also want to say hello.
Nestled in 34 acres, the cabin at Highland Springs Farm is 170 years old and was moved to the property in the 1980s. In the 1990s, an addition was added to give the structure an old farmhouse look. Each morning a classic country breakfast of regional foods, including heirloom pork, is served on the breakfast porch looking out over the beautiful grounds. The innkeepers also offer onsite dinners, if requested in advance, complete with Neely's legendary sugar cream pie.
The property boasts three unique guest rooms and has become a popular site for weddings and events. There's a large guest room renovated from a barn loft previously used for storing hay, with a sitting area and a window overlooking the animals in the barn, a private bath with radiant-heated floors, and a small porch with views of the butterfly garden. The focal point of the room is the queen bed massive headboard, custom-made from 150-year-old hand-hewn cabin posts.
with radiant-heated floors. You can view the animals from a window or the charming front porch. And in the farmhouse, a first-floor bedroom with twin beds is decorated with antiques and rustic furnishings. Rooms range from $125 to $165 a night.
In addition to unencumbered access to the animals, the property has several other amenities: walking paths, a swimming and fishing pond, an in-ground pool where you can schedule a massage, outdoor showers, and butterfly, vegetable, and flower gardens. What you won't find are televisions or clocks, although the farm does have wi-fi hotspots for those guests who desperately need internet.


In order to create this rating list of the best gallon pitcher, we had to look through hundreds of products. We compared such aspects as material, cost, weight, and many other characteristics. You can always contact us and suggest any ideas if you think that our list can be improved.
People who are looking for good gallon pitcher should find our article very helpful. It contains all the needed information about existing gallon pitcher model, as well as buying tips for beginners and the TOP list of the best products.
Will stay clear and durable even after hundreds of dishwasher cycles.
Made from bpa free material that ensures containers to be safe and eco-friendly.
Made from food-safe, plastic, bpa-free and fda-approved material.
It is safe for gas or electric stove use, and will not breakage even if you pour the boiling water or frozen water directly into it.
Dishwasher safe: will stay clear and durable even after hundreds of dishwasher cycles. Temperature resistant: freezer safe and can contain hot liquids up to the boiling point. Tritan: tritan plastic will amaze you with a glass like look and feel. Whether you drop it, throw it in the bottom of your backpack or wash it hundreds of times, a product made with tritan lasts. Square: it's a great compact shape, allowing it to hold the 64 oz, but taking up minimal room in the fridge. Unique design: great for all better drinks & beverages like ice tea, lemonade or all other homemade juice.
What warranty should be offered with a decent gallon pitcher?
We recommend all our readers to buy gallon pitcherwith at least the two-year long warranty period. This is the optimal term for an average gallon pitcher. Instead of overpaying for a lifetime warranty, save the money to buy a new gallon pitcher later.
Convenient to use: can be used in the microwave, freezer and dishwasher (top rack only). Whether it is storing leftovers or packing lunch, lock & lock are convenient to use around the kitchen or for any other household needs. Wide variety of unique, stackable designs allows you to save space in your cabinets, refrigerator, and freezer. Cultivate a healthy lifestyle and save space, food and money by investing in some lock & lock containers. Only lock & lock products "sold by" amazon. Com or lock & lock are guaranteed genuine. This assures food to stay fresh longer and keeps contents in containers secure.
Bpa free & fda approved: made from bpa free material that ensures containers to be safe and eco-friendly. Passed strict hygiene and safety tests of the USA fda and german sgs.
Perfectly houses your favorite beverage, glass bottle holds 68 ounce or 2 liter – great glass jar with lid to store milk or store-bought beverages homemade lemonade juices in durable safe glass storage container with lid for easy, feel-good enjoyment. An integrated strong handle, wide mouth built-in pour spout makes it very simple to fill with ice or any favorite cut fruits, easy to hold and dispense and hand wash them. Yet is small enough pitcher fits perfectly in refrigerator door. Modern square bormioli frigoverre glass jug with hermetic lid are the perfect glass pitcher for serving water for any occasion and enhances every table; bpa free leak proof lid, keeps beverages cold fresh and tasty for much longer.
Constructed of thick glass, the absence of lead guarantees 100-percent recyclable products; superior resistant to use and dishwasher safe guarantees long lasting product; textured glass allows for an immediate view of the beverage contained, made in italy. Not recommended for use with hot water.
What do I need to check before choosing a gallon pitcher?
Marketplace provides a myriad of convenient features to help you compare and choose gallon pitcher. It also aggregates thousands of reviews from people all over the world. Always read them before choosing a gallon pitcher!
Food safe and bpa free – made from food-safe, plastic, bpa-free and fda-approved material. Extra large capacity holds 110 ounces. Serve over 3/4 of a gallon of your favorite refreshment. Wash with cool water, not suitable for heated cycle. Sturdy enough for outdoor use, pretty enough for indoor entertaining. Great as an ice tea pitcher, sangria pitcher, lemonade pitcher or just as a water pitcher. Looks like glass, yet won t shatter. Transparent design displays your beverage, sturdy acrylic construction will not shatter like glass.
How to get a refund for a gallon pitcher?
If you receive a wrong or a broken gallon pitcher, seller will oblige the seller to return your money or send you a replacement. There is no need to worry about refunds anymore thanks to the amazing customer-friendly policy!
Ergonomic handle and pour spout: wide mouth built-in pour spout makes juice drinking hassle free. Integrated strong handle make it easy to hold, dispense and hand wash them. It is thin, lightweight, smooth surface and cleaning effortless. Stainless steel filter top: the filter lid is stainless steel and perfect for pouring water or keeping the ice cubes, sliced fruit, tea bags inside the beverage pitcher. The mouth of the pitcher is large enough to fill with ice and any favorite cut fruits. Stovetop safe: it is safe for gas or electric stove use, and will not breakage even if you pour the boiling water or frozen water directly into it. Because this water carafe is made of borosilicate glass, this material could withdraw the temperature from -4 f to 300 f. So it can be used for many types of beverages from iced water, hot tea, fruit infused juices and so on.
2.1 liter capacity / 70 oz: it can hold more than half a gallon of fluid and perfect for serving beverages for any occasion and enhances table setting. This glass pitcher looks small, but it s large enough to hold beverages for several people, and easy to store on the refrigerator shelf. The new design which makes it more beautiful, practical and stable.
Do I need to worry when buying a gallon pitcher online?
Many people use online shopping every day. It is absolutely safe because you are secured by layers of customer protection programs. You are not risking anything by ordering a gallon pitcher since you can easily return it and receive your money back. We see no reason to worry while ordering goods online — it is a convenient, cheap, quick, and, of course, safe method of shopping.
What should be the warranty period for a good gallon pitcher?
If you do not want to buy a new gallon pitcher or spend your money every time it malfunctions, consider a model with a good warranty period. Otherwise, you will have to waste a lot of resources to repair or replace it.
What is the defining factor when choosing a gallon pitcher?
As you might have guessed, the weight of a gallon pitcher is one of the main factor to consider. Another important aspects is its material. If the gallon pitcher is assembled well, it will serve you for many years.


text:
<title>The 3D Web Coder</title>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8"/>
<link rel="stylesheet" type="text/css" href="3dwc.css"/>

Tutorials, Hackergarten, CompHound React.js

Yesterday I participated in
the Hackergarten Basel September 2015 meeting and worked with
Lukas @syzer Gintowt on integrating
a Reactjs component into
the CompHound node.js mongodb web
server CompHoundWeb.

Besides that, let me mention tutorialspoint:

Tutorialspoint

CompHound React.js widget

CompHound road map

Tutorialspoint

If you are interested in learning any new technology, my colleague Cyrille suggests taking a look
at tutorialspoint.

It enables you to learn the theory and practice in a real-time hands-on lab at the same time, right there, online.
No need for any local installation of anything at all.

It boasts of having the largest tutorials library on the web, covering hundreds of topics, with a wide list of subjects ranging across all the following:

Academic

Big Data

Databases

Digital Marketing

Java Technologies

Multi Language Tutorials

Mainframe

Management

Microsoft Technologies

Questions and Answers

Miscellaneous

Mobile Development

Programming

Scripts

Software Quality

Telecom

Web Development

XML Technologies

I'm sure some of those are of interest to you too!

CompHound React.js Widget

Until yesterday,
the CompHoundWeb mongoose datatable was
driven by a Jade template file views/index.jade.

Since it is hard to combine that with a Reactjs component, Lukas replaced
it by a pure HTML file public/index.html.

We created version 0.0.16,
which I later cleaned up into 0.0.17.

I moved index.html to datatable2.html and
implemented a new route /datatable2 to it.

It is all up and running on Heroku, so you
can see the results live and the source in
the CompHoundWeb GitHub repo.
The readme there provides more info and testing links.

Many thanks to Lukas for his work and many other interesting suggestions!

CompHound Road Map

At this stage, the list of the things to work on next is still growing instead of shrinking:

Add the rest of the database columns to the datatable view.

Implement the react component to view and edit a component occurrence.

Add a View and Data API viewing component.

Implement the model translation for the viewer.

Add a database column for the viewer URN.

Implement isolated viewing of an individual selected instance.

Reroute the comphound.net domain to it.

Wish me luck on finishing this before my conference presentations
at RTC Europe in Budapest
and Autodesk University in
Las Vegas are due, end of October and beginning of December, respectively.

redpajama_set_name: RedPajamaGithub


text:
Irwin Family's Guide to Queensland's Sunshine Coast
Terri, Bindi and Robert Irwin continue Steve's legacy through ground-breaking research, conservation work around the world and their brand-new television series on Animal Planet: 'Crikey! It's the Irwins'.
The series has been Animal Planet's most popular world-wide launch ever, airing across 360 million homes in more than 205 countries and territories.
While their mission to save wildlife and wild places around the world takes them to some noteworthy places, they will always call Australia Zoo on Queensland's Sunshine Coast home.
As ambassadors for Queensland's Sunshine Coast region; the Irwin's share an insider's guide to the place they call home.
How did you come to live on the Sunshine Coast?
Terri: I visited the Sunshine Coast in October of 1991 and had a chance meeting with Steve Irwin at the then Queensland Reptile and Fauna Park. I fell in love and this visit changed my life forever.
How long have you lived on the Sunshine Coast?
Terri: I have lived on the Sunshine Coast for 26 years.
Bindi & Robert: Our whole lives!
Where do you live on the Sunshine Coast?
We live at Australia Zoo on Steve Irwin Way.
What do you love most about living on the Sunshine Coast?
Terri: I love most that we have beautiful wildlife and wild places like the Glasshouse Mountains.
Bindi: Living at Australia Zoo means that every day is a wonderful adventure.
Robert: The photography opportunities are endless on the Sunshine Coast. With some of the best world-renowned landscape locations, plus spectacular beaches are right on our doorstep.
What are your favourite things to do on the Sunshine Coast during your free time?
Terri: Visiting the shops in Maleny and dining at the Terrace Seafood Restaurant.
Bindi: Hiking with my family in the stunning Glasshouse Mountains.
Robert: Mountain biking on some of the amazing trails.
What's your favourite place on the Sunshine Coast to hang out as a family?
Terri: Watching the full moon rise over Australia Zoo.
Bindi: Sharing a picnic on top of Mount Ngungun.
Robert: Enjoying the magnificent lookout at Mary Cairncross Scenic Reserve.
What's the most surprising thing you've discovered about the Sunshine Coast?
Terri: The hinterland is even better than the beaches!
What is the one hidden gem you would recommend all guests must not miss on a visit to the Sunshine Coast?
Terri: The QCamel Dairy
Explore places mentioned in this guide
Beerwah village is one of the larger towns dotted throughout the Glass House Mountains area and offers a down-to-earth a...


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Book club, Groups, Uncategorized
Blagdon's Reading – May 2016
June 14, 2016 blagdonorg
Re-reading a much-loved book from our youth formed much of our discussion this month, Do we still find the same things funny? Is tragedy still as tragic? Do we understand a book better now, or see some aspects more clearly that were formerly obscured by the plot? One reader had been revisiting literature from the 1930s, in particular Rachel Ferguson's amusing, playful The Brontës Went to Woolworths. Three sisters, one already working as a journalist, another on the threshold of a career as an actress and the youngest still being taught by a governess (eccentrically in 1931), have to negotiate the collision between their rich fantasy lives and their incipient adulthood. 'How I loathe that kind of novel which is about a lot of sisters', says the eldest, betraying an exactly parallel collision with the premise of the book.
Elena Ferrante's My Brilliant Friend has been enjoyed and admired, and the second volume in this quartet about two Neapolitan friends, The Story of a New Name, is next on the list. These books have been called Tolstoyan in their scope and depth of feeling, and the intensity magnifies from book to book. Our reader had a warning, however, that the early, scene-setting part of My Brilliant Friend, when the two girls, Lila and Lenu, are small, though beautifully written is less engaging than what follows; so if you begin this book, do persevere until they begin to grow up.
Virginia Woolf's To The Lighthouse is also highly recommended. The first and longest of three sections takes place over the course of one day, during which the reader is invited to observe the Ramsay family, an Oxford professor, his wife (the pivot of the novel, based on Virginia Woolf's mother, Julia Duckworth, who died when Virginia was thirteen) and their eight children, on holiday in Scotland. There are also several house-guests. It is an absorbing examination of the role and worth of marriage, from the point of view of those within the marriage, those on the threshold of marriage and those on the outside. It is also about the counterpoise between past and present, at times poignantly held. The last section takes place ten years after the first.
Other books discussed included Suite Française by Irène Némirovsky, a French writer of Ukrainian-Jewish origin who planned a sequence of five novels at the outbreak of the war. Suite Française comprises the first two, Storm in June and Dolce. Already a celebrated novelist when she was writing Storm in June, Némirovsky died at Auschwitz in 1942 (her husband a few months later, in the process of trying to get her released). Her daughters survived, sheltered by teachers and friends. Denise, (who was twelve when orphaned) inherited her mother's papers in 1996. She thought the leather-bound notebook contained a journal, too painful to read, but in 2004 a literary friend realized it was a novel and set out to publish it. Although an unrevised draft, its scope and compassion have been said (by Helen Dunmore) to show her Russian origins, and comparison with Tolstoy has again been made. It is a dispassionate portrait of provincial France under occupation, not judgmental but shockingly revealing of self-preservative behaviour. At the same time, she shows compassion for the young Germans who were fodder for Hitler's megalomania. The entries in her journal about writing are fine examples of self-motivation and critical self-discipline.
The Improbability of Love by Hannah Rothschild is an art-historical novel with a twist: the title is that of a painting by Watteau, and the painting is the narrator. It tells the story of its journey from the courts of kings and emperors to a London junk shop, and the down-at-heel apartment of the book's heroine, Annie, a chef convalescing a broken heart. Hannah Rothschild will take up the Chair of Trustees of the National Gallery in August. Her book has been more than two decades in the writing, and its idea comes from visits to galleries as a child with her parents, wishing that the paintings could speak to her and tell her about their lives. Unusually, she has made this fantasy come true through her novel. Rachel Ferguson's Carne sisters would be proud!
We meet again on Wednesday June 29th at 7.30pm at the Seymour Arms.
Lindsey Shaw-Miller
lindseysm8@gmail.com
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