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Kezdőlap-Neurological-Neurological feature articles-SEEG – Overcoming the challenge of refractory seizures
SEEG – Overcoming the challenge of refractory seizures
Refractory epilepsy is clinically determined by response to anti-epileptic medications, age at onset, and seizure frequency, and can severely affect quality of life, with a significant effect on neuronal development1. Failure to successfully manage epileptic episodes in children can severely impact not only the social development of the child but also the wellbeing of their support network2. The additional time and resources required to manage the long-term programme for paediatric patients with such complex needs results in additional pressures on healthcare workers from clinicians and neurosurgeons through to hospital managers. These increase the need for earlier, more targeted interventions.
The route to seizure freedom
Surgical resection offers an alternative approach that can provide better seizure control or ultimately, lead to seizure freedom in a subset of focal epilepsy patients that are typically refractory to standard pharmacological treatment.
Accurately identifying the epileptogenic zones is critical to the success of resection procedures.
While several intracranial electroencephalography (IEEG) methods exist, minimally-invasive surgical solutions, such as SEEG, offer numerous benefits in comparison to alternative methods such as subdural electrode (SDE) implantations (Table 1).
Table 1. A comparison between SEEG and SDE. Table adapted from Fiani et al. (2021)3
Invasiveness and safety
Minimised intra-operative and postoperative blood loss
Increased risk of CSF leaks and postoperative issues
Electrode removal after monitoring in <15 minutes
Reduced hospital stay duration.
Lower cost of care
Patients require two craniotomies: for placement and for extraction.
Longer hospital stay
Increased care costs
Seizure control is more effective than SDE
Seizure control is lower compared to SEEG
DIXI MICRODEEP depth electrodes are single-use, multi-contact flexi-rigid intracerebral electrodes, manufactured using the gold standard platinum-iridium for superior smooth recording.
The success of SEEG in investigative and therapeutic procedures is increasingly influenced by innovative robotic technologies and depth electrodes.
Electrodes such as MICRODEEP® by DIXI medical, allow for deep, active bilateral exploration of the brain; with depths ranging from 16 mm to 80.5 mm, they can reach areas that are normally inaccessible during IEEG. In addition, the electrodes can be used to disorganise the epileptogenic zone, offering an alternative treatment route for children ineligible for surgery.
Clinical evidence in different applications
The use of depth electrodes during SEEG has expanded the repertoire of tools for diagnosing and treating refractory seizures in children with considerable success in several areas:
Insula/operculum (I/O) exploration4,5
Seizures originating in the I/O cortex can manifest heterogeneously as well as share characteristics with seizures originating in other lobes. Consequently, detecting and recording seizures that originate from the I/O cortex can be challenging. Without accurate recognition of the epileptogenic zone, in particular those that originate deep in the brain, the risk of a poor outcome is greatly increased. However, using the minimally-invasive SEEG with depth electrodes, clinicians have successfully identified that in around 64 per cent of SEEG cases, seizures originate in the I/O.
Epileptogenicity mapping6
One of the simplest approaches for investigating and delineating the epileptogenic zones is to map the activation level, as evidenced by changes in gamma activity, of each IEEG contact. Using SEEG and depth electrodes, variations in neural activity during a seizure can be quantified allowing for more accurate micro-resection.
Radiofrequency thermocoagulation7
In addition to identifying areas for surgical resection, depth electrodes can also be used in the treatment of refractory seizures. Creating small focal lesions that disrupt the epileptogenic zone using radiofrequency thermocoagulation (RFTC) has been shown to reduce seizure frequency and, in some cases, lead to complete seizure freedom. According to a particular study7, of patients not eligible for surgical resection, three (13.6%) were seizure-free and six (27.3%) were significantly improved after radiofrequency thermocoagulation.
The benefits of this approach are that depth electrodes are directly targeted to the epileptogenic zone and RFTC is applied during the SEEG procedure thereby eliminating the need for repeat procedures.
Identifying epileptogenic zones in children with refractory epilepsy has its challenges, with many of the methods requiring invasive procedures that increase intra- and post-operative complications.
SEEG offers a minimally invasive approach that can be successfully harnessed in the identification and treatment of paediatric refractory seizures, thanks to the effective placement of intracranial DIXI depth electrodes.
Renishaw offers cutting edge solutions that facilitate the identification of epileptogenic zones for tailored resection surgery in patients with refractive epilepsy.
Contact us onlineSEEGneuromate™Peer-reviewed articles
McCoy, B., Benbadis, S. (2010). Approach to refractory childhood seizures. Therapy. 7:497-506. Accessed at https://www.openaccessjournals.com/articles/approach-to-refractory-childhood-seizures.pdf
Dallas, J., Englot, D. J., Naftel, R, P. (2020). Neurosurgical approaches to pediatric epilepsy: Indications, techniques, and outcomes of common surgical procedures, Seizure, 77:76-85, DOI: https://doi.org/10.1016/j.seizure.2018.11.007
Fiani, B., Jarrah, R., Doan, T., Shields, J., Houston, R., & Sarno, E. (2021). Stereoelectroencephalography versus Subdural Electrode Implantation to Determine Whether Patients with Drug-resistant Epilepsy Are Candidates for Epilepsy Surgery. Neurologia medico-chirurgica, 61(6):347–355. DOI: https://doi.org/10.2176/nmc.ra.2020-0361
Kappen, P., Eltze, C., Tisdall, M., Cross, H, J., Thornton, R., Moeller, F. (2020) Stereo-EEG exploration in the insula/operculum in paediatric patients with refractory epilepsy, Seizure, 78:63-70, DOI: https://doi.org/10.1016/j.seizure.2020.02.011
Bottan, J, S., Rubino, P, A., Lau, J, C, MacDougall, K, W, Parrent, A, G., Burneo, J, G., Steven, D,A. (2020) Robot-Assisted Insular Depth Electrode Implantation Through Oblique Trajectories: 3-Dimensional Anatomical Nuances, Technique, Accuracy, and Safety. Oper Neurosurg (Hagerstown). 18(3):278-283. DOI: https://doi.org/10.1093/ons/opz154
Ayoubian, L., Tadel, F., David, O. (2020) Epileptogenicity Mapping: A Quantitative Approach to Identify the Seizure Onset, Neurosurgery Clinics of North America, 31(3):449-457, DOI: https://doi.org/10.1016/j.nec.2020.03.006
Chipaux, M., Taussig, D., Dorfmuller, G., Dorison, N., Tisdall, M, M., Boyd, S, G., Thornton, R., Eltze, C., Fohlen, M., Cross, H, J., Ferrand-Sorbets, S. (2019) SEEG-guided radiofrequency thermocoagulation of epileptic foci in the paediatric population: Feasibility, safety and efficacy, Seizure, 70:63-70. DOI: https://doi.org/10.1016/j.seizure.2019.07.004
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Therapies and procedures
Stereoelectroencephalography (SEEG)
Hírek - Neurológiai termékek és gyógymódok


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UN chief Ban apologises to Haitian people over cholera epidemic
This file photo taken on October 15, 2016 shows UN Secretary-General Ban Ki-moon visiting a shelter in the Lycee Phillipe Guerrier in the city of Les Cayes, Haiti. — AFP/VNA Photo
UNITED NATIONS, United States — UN Secretary General Ban Ki-moon yesterday apologised for the first time to the people of Haiti for the role played by the world body's peacekeepers in sparking a devastating cholera epidemic in the country.
"On behalf of the United Nations, I want to say very clearly we apologise to the Haitian people," he said three times -- in Haitian Creole, French and English -- to the UN General Assembly.
"We simply did not do enough with regards to the cholera outbreak and its spread in Haiti," Ban said. "We are profoundly sorry for our role."
According to numerous independent experts, cholera was introduced to Haiti by infected Nepalese UN peacekeepers sent to the Caribbean country after the massive 2010 earthquake.
Cholera, a disease that is transmitted through contaminated drinking water and causes acute diarrhea, is a major challenge in a country with poor sanitary conditions.
The cholera epidemic has claimed more than 9,000 lives in Haiti, the most impoverished country in the Americas, and infected 800,000 people.
The United Nations reiterated its rejection of claims that it is also legally responsible for the damages from the health emergency.
"We do not change our basic legal position," UN Deputy Secretary-General Jan Eliasson told reporters.
Ban insisted the UN has "a moral responsibility to act."
"This has cast a shadow upon the relationship between the United Nations and the people of Haiti," he said. "It is a blemish on the reputation of UN peacekeeping."
The UN chief also formally presented the 193-nation General Assembly with a "new approach," a two-pronged programme to help the families of the cholera victims and support the battle against the disease.
The UN hopes the new proposal will raise US$400 million over two years, but funding for prior UN assistance to Haiti has been slow to arrive.
Ban urged donors to finance the program. "On the scale of global humanitarian and development needs, limited sums are required to eliminate cholera in Haiti," he pleaded.
"This mission is realistic and doable. Cholera is a treatable and preventable disease. It can be controlled and eliminated."
Since the outbreak of cholera in Haiti and the ensuing accusations against the UN peacekeepers, the United Nations has steadfastly argued its missions enjoy diplomatic immunity from prosecution.
That immunity has been upheld by US courts in rejecting several lawsuits filed by victims seeking millions of dollars in damages for negligence.
To lift that immunity would jeopardise UN peacekeeping operations, Eliasson said.
"This is a true apology," he said, adding that Ban "wanted to do it before the end of his term" on December 31.
Philip Alston, UN special rapporteur on extreme poverty and human rights, said in an October report to the General Assembly that the UN's position "flouted the applicable international law" and "undermined the credibility of the organisation."
In August, the UN recognised for the first time that it brought cholera to Haiti and had a "moral responsibility" toward the victims, promising material aid. — AFP
Japanese firms wish to scale up business in Việt Nam

redpajama_set_name: RedPajamaCommonCrawl


Track and field events in the 10th Defence Services Athletics Championship - 2018 (DSAC) started on Tuesday (13) at Sugathadasa Stadium, Colombo 13.
During today's events, Private H.D.V Lakshani of the Sri Lanka Army Women's Corps by marking 13.58 meters made a new game record in the women's Triple Jump event.
The championship tournament will continue until Sunday (16) to culminate with the closing ceremony. Major General Damapath Fernando, Chief of Staff is scheduled to participate in the closing event as the Chief Guest.


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Star Trek II: The Wrath of Khan
By James Southall Saturday September 5, 2009
Composed by James Horner
Film Score Monthly / 2009 / 75:28
The fervour fans had for any new Star Trek thirty years ago was so high that even the turgid Star Trek: The Motion Picture didn't put them off. Someone evidently realised that they couldn't put out another film like that and expect to keep the punters coming in, so the studio went off in a completely different direction, pushing creator Gene Roddenberry off to one side and bringing in a new team of filmmakers, including young director Nicholas Meyer. That move is essentially the one that leaves the franchise alive today, almost thirty years later – and Star Trek II is still the film that all the others have to live up to (and none has yet come close). A classic tale of revenge, everything just works perfectly – the main cast's advancing age is not ignored but taken on as one of the key themes of the film – the villain is memorable, over-the-top, and his wrath is personal. It's a perfect Star Trek film.
By far the best element of the first film was Jerry Goldsmith's score, which is simply magnificent and one of his very best. There seems to have been no desire from Meyer to engage Goldsmith for the sequel, even if he had the budget to do so – so a young, little-known composer was given the unenviable task of stepping into his shoes. Quite a challenge for anyone, but James Horner took on that challenge, thrived under it, and almost unbelievably wrote a score which is just as good as Goldsmith's and deserves its own place in the list of the great film scores.
A young James Horner
Given his reputation (even then), and indeed the first score's reputation, it's remarkable that Horner trod a completely different musical path from Goldsmith. Meyer's instruction was to think of the film like "Horatio Hornblower in space" and that's what Horner did, with music that sounds more seafaring than spacegoing. It's in evidence from the word go, in the main title – the swirling main theme, full of adventure, is a world away from Goldsmith's stately march – but absolutely perfect for this film. It's not used that often within the body of the score, but when it is, it always leaves an impression ("Enterprise Clears Moorings" is, again, just as good as the equivalent piece from Goldsmith).
The twosome "Surprise Attack" and "Kirk's Explosive Reply" present action music at a level rarely attained. While Horner has always strived to keep his music within proper musical form, somehow writing ten-minute balletic pieces even for animated films when most of his colleagues struggle to get beyond thirty seconds in a cue, these are particularly fine examples of what makes him so good – nine minutes of fluid, vibrant music, so perfectly choreographed to the film – yet sounding so natural on the album, it might not be film music at all. He plays Khan's and Kirk's themes off each other perfectly, particularly in the first cue, which is vaguely reminiscent of the best parts of Krull.
There are two similar sequences of shorter cues, with a very different tone, occurring either side of the explosive action music just mentioned. These are brilliantly tense, with Horner capturing the horror of the characters to a tee. Then we come to the score's centrepiece, indeed perhaps the highlight of this composer's career – "Battle in the Mutara Nebula". Horner follows the increasingly desperate battle between Kirk and Khan to a tee – accentuating every high, every low, yet still keeping things flowing musically, perfectly. In eight minutes we move from despair to triumph and back again, in a film music tour-de-force that may add a debt to Prokofiev, but who cares?
The adventure continues in "Genesis Countdown", in which Spock heroically battles to save his crewmates, who must get away from impending doom as quickly as possible. Will they get away or won't they? The answer may be obvious, but that's the question Horner asks through his music, in such thrilling fashion. Of course, they do get away, but it comes at a heavy price – as evidenced in "Spock (Dies)", a genuinely touching piece of music as the beloved character takes his final bow (well, kind of final). Horner strains to wring every ounce of emotion out of the viewer – and does a fine job, with a variation on his Spock's Theme designed to bring a tear to the eye. The album ends with the great end title suite, reprising several of the main themes.
For years, we were able to enjoy 45 minutes of this magnificent music, first on an Atlantic Records LP, then a GNP/Crescendo CD. For just as long, fans have clamoured for an extended release, which seemed destined never to happen – but as someone might say, there are always possibilities – and in the end, the needs of the many prevailed. Film Score Monthly – forever, erm, enterprising – managed to secure the rights to release the complete score, and here it is for the first time. The original album featured all the best cues, but the new ones heard for the first time (away from the film) here all have a role to play. The pick of them include the tense "Captain Terrell's Death", the beautiful, shimmering "The Genesis Cave", the explosive action vignette "Enterprise Attacks Reliant" and the previously-mentioned "Spock (Dies)". Even if it weren't worth getting for the new music (which it is), then the vastly-improved sound quality would be a clincher; and there are of course extensive liner notes, including interview material with director Meyer and composer Horner. The music is Horner's masterpiece, one of the very greatest film scores, and it finally has the release it deserves. I have been, and always shall be, its friend. *****
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Tags: FSM, James Horner, Star Trek, Star Trek II: The Wrath of Khan soundtrack review
Rory Weber (Reply) on Wednesday 10 January, 2018 at 06:56
Been listening to "Surprise Attack" and "Kirk's Explosive Reply" on-and-off for about a week now. Just electrifying stuff.
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Horner reviews
Thunderheart
Composed by James HornerIntrada / 44m A very fine film, Michael Apted's Thunderheart stars Val Kilmer as an FBI agent… Read more…
Composed by James HornerHolywood / 61m We have become used to having dilemmas on how far we can separate the… Read more…
Composed by James HornerVarèse Sarabande / 56m Robert Penn Warren's Pulitzer-winning novel All the King's Men had already been adapted… Read more…
Composed by James HornerSony / 75m An unexpected smash hit, The Mask of Zorro was a thoroughly-entertaining old-fashioned adventure romp… Read more…
Composed by James HornerIntrada / 59m Released in 1993 after sitting on the shelf for a couple of years, House… Read more…
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In October 2011 the Commission published a Minimum Practice Framework as a guide to organisations providing services in the victims sector in order to identify the standards expected. Five years later, the Commission has worked on refreshing these standards in order to bring them up-to-date and reflect changes to service delivery within the sector. These draft standards are now subject to an eight week consultation process that will run to 18 November 2016.
We would encourage everyone to engage with this process and send us your views on this draft or attend one of our consultation workshops and provide us with your views and feedback.
If you are interested in one of these workshops, please regsiter with Peter at peter.mann@cvsni.org or by calling 028 90 31 1000 by Friday 7th October (Southern/Mid Ulster workshop) and by Friday 14th October (North West and Greater Belfast workshops).
Please also advise if you have any specific dietary/access requirements (buffet lunch served afterwards).
If any of the following documents are not in a format that suits your needs, please contact us and we can discuss alternative arrangements that may better suit your specific requirements.


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Current Genesis employees may be eligible to receive a bonus for successfully referring a candidate for a therapy position with Genesis Rehab Services. For program details, current employees should check the Recruiting tab of RehabCentral, Genesis Rehab Services' employee intranet. NOTE: Genesis employees who want to refer candidates for non-therapy positions with Genesis HealthCare should visit GenSERV.
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Millennium Post, Jan 2017: Waste management rules in India are based on the principles of "sustainable development", "precaution", and "polluter pays". These principles mandate municipalities and commercial establishments to act in an environmentally accountable and responsible manner—restoring balance, if their actions disrupt it. The increase in waste generation as a by-product of economic development has led to various subordinate legislations for regulating the manner of disposal and dealing with generated waste are made under the umbrella law of Environment Protection Act, 1986 (EPA). Certain forms of waste are the subject matter of separate rules and require separate compliances, mostly like authorisations, maintenance of records and adequate disposal mechanisms.


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The Rental Heart & Other Fairytales
Salt, 2014
Twenty tales of lust and loss. These stories feature clockwork hearts, lascivious queens, paper men, island circuses, and a flooded world.
On the island of Skye, an antlered girl and a tiger-tailed boy resolve never to be friends – but can they resist their unique connection?
In an alternative 19th-century Paris, a love triangle emerges between a man, a woman, and a coin-operated boy.
A teenager deals with his sister's death by escaping from their tiny Scottish island – but will she let him leave?
In 1920s New Orleans, a young girl comes of age in her mother's brothel.
Some of these stories are radical retellings of classic tales, some are modern-day fables, but all explore substitutions for love, narrated with dreamy, dark language and vivid imagery.
The book will appeal to fans of dark, adult fairytale writers like Angela Carter, Kelly Link, Margo Lanagan, Eowyn Ivey's The Snow Child, Tea Obrecht's The Tiger's Wife, Lucy Wood's Diving Belles and Jess Richards' Snake Ropes.
For signed copies of The Rental Heart, please contact Waterstones Argyle Street on 0141 248 4814. Or if you are outside the UK, please email me: hello@kirstylogan.com
Waterstones The Book Depository Your Local Bookshop Kindle
Winner: Polari First Book Prize;
Saboteur Award for Best Short Story Collection
Shortlisted: The Green Carnation Prize
Saltire Society First Book Prize
Longlisted: Frank O'Connor International Short Story Award
"Logan is an exciting emerging voice, and The Rental Heart is an addictively enjoyable addition to the welcome resurgence of the short story. It displays an unexpectedly dizzying range of styles for a debut effort, putting Logan at the top of the "ones to watch" list. It's always exciting to see such a bold, fresh new talent." – Kaite Welsh, The Independent on Sunday
"…an alarmingly good short story collection: concise, vividly written and full of dark, arresting imagery." – The Herald
"Logan is very imaginative and very fertile. She's the kind of congenial spirit that one likes to be with as a reader…this is literature that creates a realm of understanding and mutual feeling that can build something." – Marina Warner
"There are few things in this world better than a carefully crafted short story. They never outstay their welcome; simply make their mark and leave you wanting more. Kirsty Logan's recent collection, The Rental Heart And Other Fairytales, is packed with prime examples of the form; memorable snapshots of lives less ordinary." – Scots Whay Hae!
"Kirsty Logan has been slated as a writer to watch. The stories within are inventive, beautiful, and shocking by turn, and the collection is one worthy of praise and awards." – Sabotage Reviews
"An assured collection which plays with the concept of the heart as a replaceable organ, and the effect variations in heart and character would have on human existence. A disorienting but fascinating collection of stories." – Saltire Society
"The first thing that hit me about the book was the number of unapologetically queer love stories, and to my delight, in particular queer love stories of women (which as far as I'm concerned are hard to come by)." – The Gay Agenda
"I'd highly recommend this collection of stories, even if you aren't usually a short story fan. I found myself absolutely captivated from the first line of delicate, descriptive prose and am already looking forward to curling up with it for a re-read." – Like A Skeleton Key
"The Rental Heart points to three characteristics that, to me, define Logan's collection as a whole: powerful use of language; the structures of fantasy and fairytale; and a concern with love in its various manifestations." – Shiny New Books
"Recommended for: Readers who enjoy magical realism and modern fairytales." – For Books' Sake
"Logan's occasionally surreal and gorgeous tales defy categorisation" – Twin Magazine
"A great book for those who want to experience a great example of modern literary artistry; if you want to broaden your horizons we dare you to give this collection a try." – So So Gay
"A thrilling walk through a brilliant mind, full of unexpected connections and utterly original leaps across voice, structure, genre. Truly anarchic artistically but always true emotionally, and delivered with the skill of a virtuoso. Read it in one sitting for the thrill then read it again for the smarts." – Bidisha
"Kirsty Logan is an exquisite writer who possesses the uncanny ability to make even the most mundane detail beautifully compelling. If you want to be captivated, if you want to be utterly taken, reach for this book and don't let go." – Roxane Gay
"A noteworthy, wonderful read. It's rare to come across such a strong, fresh voice but this truly is totally original stuff." – Adele Patrick, Glasgow Women's Library
"Every once in a while, one comes across a writer with talent so tangible that there's no question they could ever have been anything other than a storyteller. Kirsty Logan is one such writer. She proves herself masterful at creating nuanced characters in only a few pages with a writing style all her own." – BookTrust
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The Psychology of Animals Swallowed Alive: Love Stories


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Der Pulverturm ist das letzte noch erhaltene Gebäude der ehemaligen Stadtbefestigung von Oldenburg, Niedersachsen.

Geschichte
Als Baujahr für den Großen Zwinger vor dem Eversten Tor wird in der Literatur das Jahr 1529 angegeben. Das Gebäude bestand zunächst aus einem flachen Geschützturm über einem Gewölbe. Mit dem Ausbau der Oldenburger Befestigungsanlagen Anfang des 17. Jahrhunderts ist vermutlich der Turm über dem Zwinger mit seinem Kegeldach entstanden. Die früheste Darstellung mit Kegeldach stammt aus dem Jahr 1625.

Als Teil des Eversten-Tores, bestehend aus Tor mit darüberliegendem Kommandantenhaus, Brücke und Turm, wurde der Turm in der Zeit der dänischen Festung (1730–1765) als Pulverturm genutzt und diente nach Aufgabe der Festung von 1765 bis circa 1900 als Eiskeller (Vorratsraum) für das nahe Schloss. Das gewölbte Eversten-Tor wurde 1814 und die doppelte Gewölbebrücke 1842 abgebrochen.

Restaurierung und Nutzung
Im Jahr 1964 ging der Turm vom Land Niedersachsen in das Eigentum der Stadt Oldenburg über. Nach Instandsetzung der Kuppel im Jahr 1965 wurde der Pulverturm 1966 unter Denkmalschutz gestellt.

Seit 1988 wird der Kuppelraum für Kulturveranstaltungen, sowie Kunst- und Keramikausstellungen genutzt.

Zur Untersuchung der Turmfundamente wurden 1992 Grabungen durchgeführt. Die Grabungen wurden dann 1993 durch das Institut für Denkmalpflege aus Hannover in Zusammenarbeit mit der Stadt Oldenburg ausgedehnt. In den Jahren 1995 und 1996 erfolgten Restaurierungs- und Rekonstruktionsmaßnahmen am Pulverturm und den aufgefundenen Mauerresten.

Im Jahr 2005 wurde das Gebäude für Dreharbeiten für eine geschichtswissenschaftliche Dokumentation des WDR genutzt.

Ausgleichsschichten im Mauerwerk belegen, dass die Neigung des Turmes Richtung Schlosswall bereits während oder kurz nach der Bauzeit entstanden ist. Setzungskontrollen in den letzten Jahren haben keine weitere Neigung des Gebäudes erkennen lassen.

Weblinks

Einzelnachweise

Wehrturm in Niedersachsen
Bauwerk in Oldenburg (Oldb)
Oldenburg
Turm in Europa

redpajama_set_name: RedPajamaWikipedia


A property developer who drove off with a bailiff clinging to the bonnet of his Mercedes has been jailed.
The bailiff had court papers to seize Myles Jasper's Mercedes C250 from his home on the luxury Wynyard estate, on the outskirts of Hartlepool.
But "arrogant" Jasper, 37, jumped behind the wheel and the bailiff had to leap onto the bonnet to avoid being crushed against his recovery truck.
The bailiff eventually threw himself off and he fortunately landed on his feet, said prosecutor Peter Sabiston.
The judge in the case said it was fortunate that the bailiff was not injured.
A psychiatrist told Teesside Crown Court that Jasper had a sense of superiority and the arrival of the bailiff had "burst his bubble".
Elaine Taylor, defending, said that Jasper had time to reflect on his position while on remand in jail and he had taken a number of training courses in the building industry.
Judge Sean Morris told Jasper: "You tend to consider yourself above everybody else, and when people bring reality alight for you and burst the bubble that you live in you react angrily.
"Fortunately for you no injury was caused".
Jasper, of Stockton Road, Castle Eden, who appeared over a videolink from Durham Prison, was jailed for 16 months after he was convicted of dangerous driving and common assault on August 3 last year.
Jasper was also disqualified from driving for three years and eight months and until he passes an extended driving test odered by the judge.


Cinebench is one of the strongest results for the Ryzen 5 2500U. In the multi-threaded test, the CPU was just slightly slower than the Core i7-8550U, and let's not forget the i7-8550U is a higher-tier product than the Ryzen 5 2500U. The Ryzen 7 2700U is clocked 5 to 10 percent higher, and no doubt would beat the i7-8550U in this test.
If you've been following Ryzen desktop coverage, the single-threaded result won't surprise you: the i7-8550U is a good 17 percent faster here. Interestingly, on a clock for clock basis, the 8550U is clocked 11 percent higher in single-core workloads, so read into that what you want.
Encoding x264 videos is a tougher task for the Ryzen 5 2500U. In the first pass, the 8550U is a huge 38 percent faster, though strangely this margin is narrowed significantly in the second pass to just 3 percent.
And it gets even tougher in x265 encoding, where Intel's 8th-generation parts hold a commanding lead. The 8550U is a good 23 percent faster in this workload, encoding the hour long test video in an hour and a half compared to two hours for Ryzen.


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I was fortunate to have the expertise of Shayne Parrish working alongside me when launching my website. Not only is Shayne a talented designer and collaborator, but he will stick with you from start to finish…and then, without any hesitation, will be there to do any further updates and/or changes you need. You can depend on his professionalism 100%.
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Working with Parrish Digital has been like a breath of fresh air. They are professional, responsive, creative, solution-oriented. There wasn't a question that they didn't answer immediately or a request that was asked that was not acted upon in a very timely fashion. Parrish Digital is an exemplary model of professionalism and have been a pleasure to work with. I highly recommend for web-design and maintenance.
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text:
Govt sets conditions for Nyege Nyege festival
Poetry enchants revelers at Kwivuga night...
Ugandan filmmakers to revolutionize film...
By Cecilia Okoth
Added 5th September 2019 07:07 AM
The conditions according to state minister for ethics, Fr Simon Lokodo bars participants from engaging in any sexual activity, violence and drug abuse.
Ethics minister Simon Lokodo said the festival will be closely monitored by Police, the army and other sister security agencies (File photo)
Government has set tough conditions for this year's Nyege Nyege cultural festival.
The conditions according to state minister for ethics, Fr Simon Lokodo bars participants from engaging in any sexual activity, violence, and drug abuse.
"I do not expect people to attend the festival in attires that leave their breasts or bums out. Women should also not wear bikinis during the day," Lokodo said, adding that indecency and nudity are totally prohibited.
Lokodo who was speaking to the New Vision on Wednesday said the festival will be closely monitored by Police, the army and other sister security agencies to ensure that nothing goes out of hand.
Revellers having fun at the festival
The minister explained that government, on the advice of President Yoweri Museveni, directed that certain conditions be given to the event organisers prior to the festival.
This, he said was agreed upon during a meeting that took place on Tuesday amongst officials from the Internal Affairs Ministry, Gender Ministry, the Department of Ethics and Integrity, Police, UPDF and CMI.
"Open sex or any sexual activity which has been the practice of nyege nyege shall not be allowed. The police and army, both in uniform and civilian attire will be given free access to the venue and if they catch anyone engaging in any king of immorality, he or she shall be arraigned in the courts of law," Lokodo explained.
He also warned participants against driving under the influence of alcohol.
According to a memorandum of understating between government and the organisers, in the event of breach of any or a combination of the above terms, government reserves the right to call off the event without notice.
Polly Namaye, the deputy police spokesperson, said the organisers of the event agreed to provide a detailed programme of the event to inform the deployment of security personnel as well as free access for the joint security at the venue at any point in time.
The festival attracts tourists too
"The organisers elaborated that the purpose of the event is to promote culture and local music and these are some of the key aspects that were embedded in the Memorandum of Understanding," she said.
Namaye said narcotic drugs substance and any form of drug abuse shall be prohibited, adding that the anti-narcotics units have been tasked to ensure compliance to this measure.
"Police will also ensure that the venue is accessed by only adults and anyone whose age is questionable shall be required to provide documentary evidence to prove their age. The event will not be turned into a political event," Namaye said.
Nyege Nyege is a Luganda word meaning 'the feeling of a sudden uncontrollable urge to move, shake or dance'.
The festival's name evokes different meanings among the East African countries. While in Uganda it refers to the uncontrollable urge to dance, Nyege amongst Swahili speakers has sexual connotations.
The festival, set to begin today (Thursday) at the Nile Discovery Beach in Buikwe district ends on Sunday.
Govt green-lights Nyege Nyege Festival
What to expect at Nyege Nyege Festival
Doing The Nyege Nyege On The Nile
Life and style,
Nyege Nyege cultural festival.
677 to graduate at Law Development Centre
UBL launches sh20b waste treatment plant
Busoga target for this year's immunisation week
Over 4000 nurses, midwives begin exams
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AFP, MUNICH: Germany are trying to move into a new era after their disastrous World Cup campaign, but Thursday's 0-0 draw with France showed the importance to coach Joachim Low of keeping faith in the old guard.
Low's starting line-up at the Allianz Arena against the world champions featured five members of the German team that beat Argentina in the 2014 World Cup final -- goalkeeper Manuel Neuer, centre-backs Mats Hummels and Jerome Boateng, midfielder Toni Kroos and forward Thomas Mueller.
That quintet, with over 400 caps between them, made up the spine of the team that would have beaten France were it not for some exceptional saves from visiting goalkeeper Alphonse Areola, notably from Marco Reus, Mueller and then Matthias Ginter in the second half. All of Germany's starting line-up for their first match in the inaugural UEFA Nations League had been part of their squad in Russia, when they were knocked out in the group stage. The only changed face was Leroy Sane, the Manchester City winger coming off the bench late on having been controversially left out of the 23 for the World Cup. The likes of Thilo Kehrer and Kai Havertz stayed on the bench.
"Of course we need to integrate new players. We always need to be pushing to do that, but it is a process that will not happen overnight," Low said after the match.
Low also opted to start with Ginter and Antonio Ruediger, centre-backs by trade, in the full-back positions, a decision that was rewarded as Germany kept Kylian Mbappe, Antoine Griezmann and company at bay.
"It was a bit frustrating that we didn't score a goal. But we wanted to keep it tight after what happened at the World Cup. That was the priority. I think we succeeded," said Kroos.
Germany, who host Peru in a friendly in Sinsheim on Sunday, are hoping to definitively move on from the fall-out of their World Cup debacle. That has been marked by Mesut Ozil's decision to retire from international football amid allegations of racism aimed at the German FA (DFB) president, Reinhard Grindel.
AFP, MUNICH: Germany are trying to move into a new era after their disastrous World Cup campaign, but Thursdays 0-0 draw with France showed the importance to coach Joachim Low of keeping faith in the old guard. Lows starting line-up at the Allianz Arena against the world champions featured five members of the German team that beat Argentina in the 2014 World Cup final -- goalkeeper Manuel Neuer, centre-backs Mats Hummels and Jerome Boateng, midfielder Toni Kroos and forward Thomas Mueller. That quintet, with over 400 caps between them, made up the spine of the team that would have beaten France were it not for some exceptional saves from visiting goalkeeper Alphonse Areola, notably from Marco Reus, Mueller and then Matthias Ginter in the second half. All of Germanys starting line-up for their first match in the inaugural UEFA Nations League had been part of their squad in Russia, when they were knocked out in the group stage. The only changed face was Leroy Sane, the Manchester City winger coming off the bench late on having been controversially left out of the 23 for the World Cup. The likes of Thilo Kehrer and Kai Havertz stayed on the bench. Of course we need to integrate new players. We always need to be pushing to do that, but it is a process that will not happen overnight, Low said after the match. We saw that against a team as strong as France, players like Hummels, Boateng and Kroos are extremely important, because of their class, their experience and their quality. The youngsters will get their opportunity. Low also opted to start with Ginter and Antonio Ruediger, centre-backs by trade, in the full-back positions, a decision that was rewarded as Germany kept Kylian Mbappe, Antoine Griezmann and company at bay. It was a bit frustrating that we didnt score a goal. But we wanted to keep it tight after what happened at the World Cup. That was the priority. I think we succeeded, said Kroos. Germany, who host Peru in a friendly in Sinsheim on Sunday, are hoping to definitively move on from the fall-out of their World Cup debacle. That has been marked by Mesut Ozils decision to retire from international football amid allegations of racism aimed at the German FA (DFB) president, Reinhard Grindel.


Opening this Guide is like opening a door into Global Interaction's world. We invite you to come in and unite with Australian Baptists as we reach out to the least-reached with a special concern for those who have been pushed to the edges of their society.
Currently two thirds of the world's population are yet to experience the life-transforming gift of Jesus. So many people go from birth to death without ever hearing the Good News of Jesus Christ. Global Interaction is devoted to sharing Jesus with these communities around the world.
Why are we so passionately focused on least-reached people groups? With 97% of the world's Christian workers and resources focused on the people who have already encountered Jesus, we think that those who may miss out on that opportunity deserve our attention and priority. Yes there are many worthy causes in the world today but we firmly believe that at present, God has called Global Interaction to be a presence and a light to nine of these least-reached people groups.
Ponder over the pages, imagine the places and the people and ask God what valuable contribution you can make. We refer to this Guide throughout the year in our prayer resources. We hope that it will help you as you pray to visualise the incredible work that you are supporting.
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When work is carried out on the water supply network or if there is a break, pressure changes may dislodge rust in certain pipes. The water remains drinkable even if it is slightly discolored. However, since il can stain clothing, we recommend that you check the color of the water befor doing a washing. If it is discolored, you should let the tap run until the water runs clear.


text:
U-204 — средняя немецкая подводная лодка типа VIIC времён Второй мировой войны.

История
Заказ на постройку субмарины был отдан 23 сентября 1939 года. Лодка была заложена 22 апреля 1940 года на верфи «Германиаверфт» в Киле под строительным номером 633, спущена на воду 23 января 1941 года. Лодка вошла в строй 8 марта 1941 года под командованием оберлейтенанта Вальтера Келя.

Флотилии
 8 марта — 1 мая 1941 года — 1-я флотилия (учебная)
 1 мая — 19 октября 1941 года — 1-я флотилия

История службы
Лодка совершила 3 боевых похода. Потопила 4 судна суммарным водоизмещением 17 360 брт и один военный корабль водоизмещением 1060 тонн.

Потоплена 19 октября 1941 года в районе с координатами  глубинными бомбами с британского корвета HMS Mallow и британского шлюпа HMS Rochester. 46 погибших (весь экипаж).

См. также
 Список подводных лодок Третьего рейха

Ссылки

Литература


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MINNEAPOLIS (WCCO) — Minnesota's East African leaders are calling for a $15 an hour minimum wage at the airport.
That's nearly double the state's current minimum wage of $8 an hour.
A new employment report shows thousands of East Africans working at the airport are earning poverty-level wages.
More than 2,500 East Africans work at the Minneapolis-St. Paul International Airport, according to a report by The Center for Popular Democracy — making the airport the largest employer for Minnesota's newest immigrants.
Most of them work in minimum-wage jobs, like cart driver Abdi Ali.
The report says 63 percent of Minnesota Somalis live at or below the poverty level, and it's calling for a wage increase to help raise living standards.
"We found that raising wages to $15 for airport workers would bring — just to the East African community — $30 million to the local community," report researcher and author Eden Yosief said.
Airport workers are employed by private airlines and related businesses. The Metropolitan Airports Commission recently required companies to offer paid leave.
"The Metropolitan Airports Commission has long had a strong relationship with labor and takes steps to ensure vendors providing services to the Commission compensate their employees fairly for that work.
At issue are employees who work for private businesses under contract to airlines. In December the Commission board passed a policy requiring those businesses to provide paid leave to their employees and to protect employees should an airline change service vendors.
Gov. Mark Dayton says he'll support a $10 airport wage, and says businesses opposing it cannot threaten to move.
Minnesota raised the state minimum wage to $8 an hour last August.
The wage is scheduled to go up to $9.50 an hour next year.


text:
What Can Brown Accomplish On His Mexico Trade Mission?
Monday, July 28, 2014 | Sacramento, CA
Gov. Jerry Brown and First Lady Anne Gust Brown open the California-China Office of Trade and Investment in Shanghai on Brown's last trade mission in April 2013.
Photo: Office of Gov. Brown
California Governor Jerry Brown is spending much of the week in Mexico on what his office calls a "trade and investment mission." But what can a state trade mission like this
actually accomplish?
When we posed that question to Jock O'Connell, a trade expert with the firm Beacon Economics, he paused for about four seconds before responding: "Good question!"
After all, states don't have a say in U.S. foreign policy. Brown acknowledged as much last week when he previewed his trade mission at the California Chamber of Commerce: "There are a lot of big issues that cause concern in both countries. I'm ot quite sure what a state governor can do. But if there's anything I can do, I'll find a way to do it."
So what can Brown do? O'Connell says that depends. Sometimes, the trips are just for the vanity of the governor. "But when missions are carefully focused – when they're primarily business missions, in which the governor is a party to it, then you can expect some gains."
Mexico is California's largest trading partner, and Brown hopes to boost trade opportunities and expand economic cooperation. "The business of buying and selling is not business of government, but our job is to open doors or to facilitate understanding and make all that possible," he says.
That may not be the only reason business leaders are paying $5,000 each to join the governor, top administration officials and several state lawmakers on the trip. O'Connell says the cost is well worth the access. "There are any number of organizations and businesses that has interests that they want to advance at the state Capitol who are glad to spend $5,000 to spend some time up close and personal with the governor," O'Connell says.
Brown's trip isn't just about trade; he also plans to discuss immigration, and urge Mexico to pursue what he calls an "intelligent" agenda on climate change.
jerry browntrade missionMexico
Director of Programming and Audience Development
Director of Programming and Audience Development Ben Adler first became a public radio listener in the car on his way to preschool — though not necessarily by choice. Read Full Bio
More State Government Stories
California reparations task force zeroes in on who'd be eligible for compensation


text:
North Korea hints at restart of nuclear, missile tests, calls US…
EU Parliament and Social Media Platforms
EU political system facing threats from Political Cyber Gaming for Perception Building
By Shazia Anwer Cheema
On November 8, the European Parliament Committee on Internal Market and Consumer Protection conducted a Public Hearing where the whistleblower Frances Haugen was invited t6 give testimony on the negative impact of social media products on users.
Members of the European Parliament (MEPs) asked her several questions about harmful technical practices of social media platforms and she briefed them on how social media platforms gather private data, use it for commercial purposes, and how Facebook keeps engaging people on the platform, and why. She also talked about the adverse impact of social media platforms on youth and how one can save youth from adverse impacts. The adverse impact of Instagram was the major issue for members of the European Parliament, therefore they raised several questions about Instagram-related suicides among youth and vulnerable people.
After her briefing, there was a question and answer session. I attended both the sessions online to understand the subject of online safety and its priority for the European population, the rapidly changing online world, and how to ensure a better and safer digital environment for internet users.
MEP Christel Schaldemose (SD, Denmark) who leads MEPs for the Digital Services Act (DSA) was of the view that all users of Facebook should know and understand to the greatest extent the business model and the choices behind the operation of the platform while Andreas Schwab (EPP, Germany) indicated that Facebook plays (played) a large role in modern society and it shows users political advertisements and political content based on our personal data, and this practice can create "echo chambers".
European politicians strongly believe that there is a dire need to regulate online political content and the social media platform (Facebook) should use data of users with the informed consent of the users, and the mechanism behind the algorithm should be shared with users so they can know the risk that any algorithm or change of algorithm poses to the users and make the platforms accountable for the adverse impact of the recommended systems and algorithms.
This Public Hearing indicates that the European politicians and political parties feel threatened with a new kind of "Perception Building" against political systems and democracies. I believe the most vulnerable are democracies in the developing world where they already face pressures from establishments and powerful corporate giants, and one can understand establishments and corporate giants can use social media platforms for "regime change" without coming at the front. We understand a "deceit game with deceptive tools" is being played against many countries, against several political parties, and against a number of individuals through Social Media Campaigning in South Asia.
It is pertinent to mention that the European Parliament is working to make the "Digital Markets Act" (DMA) for ensuring the privacy of users so that personal data can only be used for political advertising if users give their renewed consent.
According to the office of the European Parliament Committee, "digital transformation is one of the EU's priorities and the Parliament is helping to shape the policies that will strengthen Europe's capacities in new digital technologies, open new opportunities for businesses and consumers and that is the reason that EU Parliament in May 2021 adopted a report on shaping the digital future of Europe. EU is investing €7.6 billion in five areas: supercomputing (€2.2 billion), artificial intelligence (€2.1 billion), cybersecurity (€1.6 billion), advanced digital skills (€0.6 billion), and ensuring a wide use of digital technologies across the economy and society (€1.1 billion). Therefore, online safety, the transparency of algorithms, and risk mitigation are important issues for Europe.
Important points Haugen shared with members of EU Parliament during her testimony include:
One out of three social media users is under 18 years of age.
The users of Instagram feel fear —- I cannot stop myself –I will be cut off from my family and friends if I will stop using it.
We really need a system instead of blaming parents.
Parents want to keep their kids busy sometimes and ask them to use social media.
Facebook discourages research on the impact of social media on kids and for developing meaningful social interaction.
Data gathered by Facebook should continuously be shared with the public and data monitoring is needed
Hate speeches are also considered as social media interaction
Producing more content is the game of Facebook and this is done through creating contradictions and encouraging contradictions including hate speech
Negative comments are encouraged and radicalization is also considered "debate"
We do not know what actually is going to happen with the data we share with social media platforms?
It is the responsibility of social media platforms to tell people about the impact of social media but the assessment process has been stopped inside Facebook operations.
Data streaming should be released on a monthly basis.
There should be a centralized authority in Europe to keep an eye on Fake News and Misinformation.
US and EU approaches are different on privacy and morality while a majority of social media platforms are registered in the USA and follow US rules and ethics.
Facebook hides the data of impact on people because Facebook knows if data is shared with users they would avoid coming on it (Facebook).
People Tracking is a forced option without their awareness.
Creating "Hate and Division" among social groups is the lethal game of social media platforms.
Whistleblowers are important and they have protection under US rules.
Shadow profiles are on social media to engage people.
Instagram and Facebook are providing misinformation and the most vulnerable are those who are already in a lonely phase like divorced people, living single etc
You are invited into groups — but leaving a group does not mean that your data has not been shared and gathered by a new group you join even for one minute.
The Facebook algorithm is tricky and the EU has a big role to discuss these issues because it is a real democracy.
Social Media Platforms must tell what backend system they have for security and data collection.
End to end encryption —-Facebook does not share what kind of encryption it has. People would be shocked one day when Facebook would disclose it.
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Shazia Anwer Cheema
The writer Shazia Cheema is an analyst writing for national and international media outlets. She heads the DND Thought Center. She did her MA in Cognitive Semiotics from Aarhus University Denmark and is currently registered as a Ph.D. Scholar of Semiotics and Philosophy of Communication at Charles University Prague
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