The Apple iPad Pro Tablet sports a 10.5-inch retina display with a resolution of 2224x1668 pixels. Powered by the A10X Fusion chip, and M10 motion coprocessor, it provides high speed and efficiency. This space gray, Wi-Fi + 4G model has a storage capacity of 512 GB, and runs on the IOS operating system. It features a 12 MP iSight camera, allowing you to capture sharp and detailed photographs. In addition, this tablet supports the Smart Keyboard and the Apple Pencil. This device is compatible with Straight Talk, Verizon, Boost Mobile, Sprint, U.S. Cellular, AT&T, T-Mobile Carriers.
The best tablet ever made.
This my second tablet after 6 years using the iPad Air I was so exited in got a more capacity and speed. This new iPad Pro with 4 speakers are amazing loud powerful sound great speed and more thinner. I'm really in love with this new tablet with a perfect 10.5 screen size. Highly recommended for any use. Not a toy for kids of course. Is super strong it feels out down from my car dashboard and hit the middle of the road and it still working perfectly. WoW..
the iPad 10.5 is the perfect size not too small as the mini one and not too big as th 12.9 inch model.
Maybe one of the last iPad Pro 10.5s with a headphone jack!
I'm glad I was able to score this iPad. I haven't even cracked the box, but it's the third iPad I've owned, and they're fabulous tablets. I'm glad I get the headphone jack for another few years.


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text:
Berkeley English Graduate Students
Sarah Sands Rice
Office: Zoom!
Weds. 6-8 pm
sarahsandsrice@berkeley.edu
Renaissance and Early Modern
Selected Publications and Papers Delivered
"'This bastard graff shall never come to growth': Conception and Consent in Shakespeare's Lucrece." Shakespeare Quarterly 72, forthcoming in 2021.
"'Full of pins (or arrows)': Renaissance Art and Sadomasochistic Aesthetics in "The Love Song of St. Sebastian.'" Yeats-Eliot Review 33.1-2, forthcoming.
"Imagination as a Biological Force." Panel: "Milton and Materiality." International Milton Symposium. Strasbourg, France. 2019.
"Perverse Sights: Dissection in 'Tis Pity She's a Whore." Seminar: "Invisible Presences." Shakespeare Association of America Annual Meeting. Washington, D.C. 2019.
"The Poetics of Anatomy in Henry Power's 'Microscopicall Observations.'" Panel: "The Science and Poetics of Sight." Society for Renaissance Studies Eighth Biennial Conference. Sheffield, England. 2018.
"'To Thy Mother Dead Attest': Legal Rhetoric and the Sign of Blood in The Faerie Queene II.i." Berkeley-Stanford Conference. University of California, Berkeley. 2016.
Recent English Courses Taught
R1A/7
Reading and Composition: Love and Its Discontents in Shakespeare's England
Reading and Composition
R1B/5
Reading and Composition: The Monstrous Renaissance

redpajama_set_name: RedPajamaCommonCrawl


If you see Roger biking down Elim's outdoor paths, don't be surprised to hear us enthusiastically cheering him on!
Everyone makes progress in different ways, and at Elim, we celebrate accomplishments, no matter how big or small they might seem to someone else.
For many years, Roger showed interest in riding a modified bicycle, but he struggled to tolerate wearing a bike helmet. Elim's therapy and teaching staff never gave up, persistently encouraging and exposing Roger to the equipment he needed to make his biking dreams a reality. In June, Roger finally did it! Proudly wearing his helmet, Roger rode a tandem bike with his assistant teacher, his happiness evident to all!
Biking is just one area where Roger experienced huge strides this year. Just a couple of years ago, found it difficult to take part in classroom activities and community outings. Elim's team knew the potential of this young man and worked hard to equip him with the communication skills and strategies he needed to be able to enjoy activities with others.
Today, and because of your support, Roger loves community trips, visiting chapel, and attending assemblies and sporting events. He enjoys participating in classroom activities with his friends and has built strong relationships with Elim's staff.
Oh, and biking too. He loves biking.


When Mallory contacted me to talk birth photography she knew the birth of their 2nd child would be by cesarean at Kootenai Health. She had high hopes of having the full procedure documented and I am thrilled that we were able to provide just that for her. Her OB, Dr. Henneberg, knew how important this moment was to her. In most cases with cesarean birth the anesthesiologist has say over who is allowed into the OR. I am beyond thankful that both he and Dr. Henneberg granted me access to fully tell their story. Because her cesarean was scheduled and not an emergency I was able to be with them the entire time, through intake up until family was welcomed back to meet their newest miracle. Here is a little glimpse into their story!
If you are interested in having your home birth, hospital birth, VBAC, or cesarean birth documented please contact me today!
Such beautiful pictures!!! brings back memories. Thank you for allowing us to see this beautiful event!!!!!


Andrea Liatis was recently awarded a R36 Mental Health Dissertation Research Grant to Increase Diversity by the NIH National Institute of Mental Health for two years at $35,000 per year. The award will fund her dissertation research project entitled, The Role of the Sympathetic Nervous System in Major Depression and Inflammation.
This proposal will provide insights into possible mechanisms linking inflammation to major depression and will help identify molecular targets related to the sympathetic nervous system contributions to the relationship among stress, depression, and disease. Activation of the innate immune system may play a role in major depression and may contribute to the detrimental impact of major depression on the development and outcome of medical illnesses including cardiovascular disease, diabetes, and cancer. Stress, a well-known precipitant of major depression, also activates the innate immune system, and an exaggerated inflammatory response to stress is seen in patients with major depression and early life stress. Studies have shown that stress-induced increases in inflammatory responses are mediated in part through the release of catecholamines and stimulation of alpha-I adrenergic receptor subtypes. In contrast, beta-adrenergic receptor subtypes have been shown to inhibit inflammatory responses. Andrea's research will investigate the role of alpha-1 and beta-2 adrenergic receptor subtypes in increased inflammation in patients with major depression and varying levels of early life stress.
Her preliminary data indicates that inflammatory stimuli upregulate mRNA expression of the beta-2 receptor in a human monocytic cell line, THP-1. The goal is to investigate the mechanisms of increased inflammation in major depression with an emphasis on the role of the sympathetic nervous system, catecholamines, and their receptors. The long-term objectives are to further explain the mechanisms that contribute to increased inflammation in major depression and early life stress. The information gained may reveal specific receptor subtypes and signaling pathways that may contribute to an increased sensitivity to catecholamine-induced inflammation in depressed patients, thus revealing novel targets for therapeutic intervention.
Andrea was among the first trainees in the PhD/MSCR dual degree program funded by the TL1 component of the Research Education, Training, & Career Development (RETCD) program of the ACTSI. "It is one of my career and research goals to bridge the gap between basic science and clinical research. My experience in the MSCR program has equipped me with all the necessary skills to accomplish this feat," said Andrea. She recently completed the requirements for the MSCR and is working on her PhD dissertation. Andrea received her BS in Biology from GA Tech, is currently working towards her PhD from Emory University's Graduate Division of Biological and Biomedical Sciences, Neuroscience, and is currently being mentored by Dr. Andrew Miller.


text:
9 things to do at TCU in '09
Mem´ries Sweet
Comrades True
TCU Magazine "Cover Story"
Other paths traveled...
Pulling out all the stops |Facing Lithuania | Size wise
Now and Zen -- Claude Ware '46
Each morning begins at six.
An hour of meditation.
Twenty minutes of T'ai Chi Ch'aun, 88 fluid movements in all.
A hike around a park.
A vegetarian lunch.
Then, a few administrative duties for Bao Phap, a developing monastery for the International Buddhist Cultural Heritage Foundation in Monterey Park, Calif., All in all, it's a quiet, meditative life of study and service for 78-year-old Buddhist monk Claude Ware '46 (MBA '48).
And quite different from what the former TCU jazz drummer and Southern Baptist envisioned while gobbling fries in his parents' Fort Worth burger joint at Magnolia and Jennings in the early '40s.
"I was raised in a good Christian home, went to church and belonged to a youth group but never felt a connectedness," said the man who walked a rather ordinary road before his Buddhist ordination. "It took years of going down the road I was on before I realized there was something else. All of a sudden I had these two paths that I could take."
His road diverged in 1976, the year he met Thich Thien An, a Buddhist master who was teaching Zen philosophy at UCLA. "This man coming into my life made all the difference. I didn't even have to stop and ask myself. They say when the student is ready, the master would appear. I was ready and there he came."
The musician whose education was paid for with jukebox nickels doesn't regret taking that divergent road. It led to inner peace and contentment. Still, Ware recalls with great fondness early days with the band, especially one particular trip to New York with bandleader Don Gillis and brand new band uniforms, thanks to Fort Worth newspaper mogul Amon Carter. It was there that the TCU Jazz Band made a name for itself performing on the steps of city hall for Mayor Fiorello LaGuardia.
Ware, who now serves as the administrative assistant for the Secretary General of the Vietnamese American Buddhist Congress, acknowledges his path toward enlightenment was circuitous. In the years between TCU and ordination, the now-divorced Ware earned a doctorate, raised two children, taught psychology at various institutions and applied human factors to operating equipment in the aerospace industry. After tiring of that, he ran a private family and marriage clinic while working for the County of Los Angeles as a research analyst, specializing in drug and alcohol abuse, a topic he came to know intimately over a seven-year period that included a breakdown and two heart attacks. Desperate to recover his ruined health, Ware turned to meditation and began studying the philosophy that eventually became his destiny.
"Buddhism is really the leveling force behind my ability to stay sober," said the monk, now dry for 33 years.
The man who jokes that he's the only "round-eye" at the temple is happy and content with his decisions. Except one.
"I've often thought I should have stayed on the faculty at TCU," he said, referring to his two years as a graduate student teaching psychology. Those were the same years he wiled away evenings plunking the piano for the Curley Broyles '44 Band. "Staying at TCU was one road I should have taken."
So, the teaching continues. Ware regularly leads chants and adorations and presents Dharma, or law, talks for the English-speaking members. He still guides T'ai Chi students through private lessons and teaches meditation traditions (also the focus of his book) at a local Chinese Buddhist college.
"Teaching keeps me involved," he said. "I'm certainly not a perfect human, but I want to tell others what I've found and it's the best way I know."


text:
Claudia Kinney
January 25, 2022 9 Condolences Print Obituary
On January 23, 2022, Claudia left us to join family and friends who were awaiting her arrival in the Sky Garden.
Two weeks shy of her 91st birthday, she has left behind a legacy of kindness, thoughtfulness, and grace. She loved all things green and growing, and had a special fondness for dogs. She saw goodness in everyone, and lived by her mantra, What Will Be, Will Be. In her final days, when she acknowledged that she was facing her own imminent mortality, she asked that she be remembered by all that knew her, by way of a Toast 'to Claudia and her great life' with a glass of your favorite wine, as she begins her final journey.
Her husband of 70 years, Max, and children, Guy, Kevin and Brenda, with their families, will endeavor to embody the attributes that were part of her being. She was so very proud of her grandchildren, and was thrilled to have lived long enough to know her great grandchildren.
While grief is the price we pay for love, she asked that no one be sad, but to be happy that she lived the life she chose, surrounded by her family and friends, her flowers, and her garden with its legendary cucumbers, carrots and tomatoes. A private celebration of her life will occur when it is safe to do so.
Claudia loved flowers, but, she loved knowing that her family and friends were safe on the roads they frequently travelled. Rather than any floral tributes, if you wish to acknowledge her remarkable life, please consider a Tribute Gift to Stars Air Ambulance.
We love you more….
Anne Vuong . on Terence Nicholas Choo
Jenny & Mike Cooper on January 25, 2022 at 9:33 pm
Deepest Sympathy to the Kinnney family. Beautifully written tribute and a "toast to her new journey". Hugs to all that your memories of Claudia bring you peace and warmth in your heart.
💐❤ Mike & Jenny
Kevin Gene Kinney on January 26, 2022 at 9:58 pm
Thank you Mike and Jenny. ❤
Tony da Silva on January 26, 2022 at 10:50 am
My deepest condolences to Claudia family.
I will go to miss Claudia and her stories when she
Was working on garden .Rest in peace
John Gantly on January 26, 2022 at 9:39 pm
Claudia was a wonderful person, always so kind and easy to talk to. She was a super baker, everything she made was so tasty. I will always have fond memories of her. My heart felt wishes and prayers go out to her family and friends.
Cheryl C Silzer on January 27, 2022 at 12:33 am
So sorry to hear of your loss, She was a beautiful woman inside and out.
Michael and Donna Kinnee on January 29, 2022 at 6:39 pm
As kids, Aunt Claudia was always one of my favourites, she spoiled all of us and was warm, genuine and caring. As we all grow older, we as families sometimes drift apart and don't see each other as often as we should. But, we never forget the good ones in our lives. To my cousins Guy, Kevin and Brenda and your families, our deepest condolences on your loss.
Tim and Cathy Blanch on January 29, 2022 at 7:02 pm
Uncle Max, Brenda,Guy, Kevin and Families. Our deepest condolences. I have such wonderful memories of Auntie Claudia, many family get together when we were young. Always smiling and the sweetest lady.
Rest in piece sweet angel
Tim and Cathy Blanch (nee Kinnee)
Connie (Burbee) Hucul on February 28, 2022 at 1:55 pm
Condolences to Claudia's family and friends! It has been many years but I so remember this lovely lady from when we were both younger !
Deb Crozman on April 15, 2022 at 11:33 pm
To Max, Guy, Kevin and Brenda,
I was very surprised this week to hear of Claudia's passing in January.
I remember you guys coming to my grad dinner in Kelowna and Claudia getting the waiter's phone number for me. I enjoyed talking family history with her and she will be missed.
Deb Crozman nee Shaw( Uncle Bill's daughter)


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This work describes how "quantum teaming" extends human capabilities for collaborative creative work.
DePriest, Desiree L. (2016) "Quantum Teaming in the 21st Century Self-Information Age," C2C Digital Magazine: Vol. 1 : Iss. 5 , Article 12.


We'll pull back, my hearty, and take a look for our gay cap'n.
He didn't say anything, but began to pull back, and dig his heels into the sand.
The cook will have a snack for you before you pull back to Oban.
Had to pull back on my stick to keep from crashing into him.
I cannot resist the temptation to pull back the slide from one episode of the past.
On seeing this, Mr Tarwig gave the order to the other boats to pull back.
If there are, we will pull back and try to bring them on shore.
We may sail to the harbour, but we shall have to pull back with the loaded boat.
Bring tears of vexation at the emptiness we pull back for our pains.


From 20 June to 14 July 2016, 25 young enthusiasts in coding were able to be part of the mYouth Training, the main Mobility of Youth Workers activity within the mYouth project.
This 25-day power program took place in Skopje and Ohrid, Macedonia, where Android classes for advanced app development were provided by the international software development and consulting company Seavus. The 25 participants who came from Senegal, Italy, Poland, Hong Kong, Austria, Spain, Bulgaria, Macedonia and Ghana learned computer programming (learning-to-code) and problem-solving (coding-to-learn). Aside, the participants received the training on business modeling and marketing for their mobile apps.
Participants of the mYouth training in Skopje boosted their skills in the development of Android mobile apps, which was related to youth and learning. Therefore, this designates to encompass a major activity for building a stronger establishment of the mLearning model, the learning model of the future. During the training ten Android, mobile apps were produced.
The participants who attended the training in Skopje were selected through the local mobile coding camps which were taking place in each of the ten partner countries for the project. The training in Macedonia was their chance to complete their mobile apps and also to polish their digital skills in coding.
Why did we do this course?
mYouth in particularly highlighted the role of mobiles, and their potential to be centered in an exact educational model. In a society where access to knowledge and information is a continual increase of importance, the mobile as a technology asset holds the capacity to reduce gaps between "the haves" and the "have-nots" of one individual. Such model, as Traxler announces is, the m-Learning, a type of "learning that is not 'just-in-case,' education for the sake of producing a bank of knowledge, but rather represents learning that is 'just-in-time,' 'just enough,' or 'just-for-me'". Our Android mobile applications program course is set on a mission to stimulate participating students to research, design and create relevant digital products. During the course, participants were able to work in groups; thus they were able to determine the issues they want to tackle and solve, and tried to answer these matters through the usage of mobile applications.
Focusing simultaneously on solving real problems that matter to youth and their local communities, the students learned about thesoftware product development process in a hands-on way.
The "coding" adventure did not end here. In fact, the journey was just to begin here. Once the mobile apps were completed, invitations to apply for the European Youth Award (EYA) or the World Summit Youth Award (WSYA) respectively were waiting for participants. Both the competitions reward best digital achievements in the field of youth and education across Europe and the world, organised by the International Center for New Media (Austria), partner of this project.


text:
Ultraviolet South Pole
This ultraviolet view shows wavy cloud bands near Saturn's south polar region. Though the region has some visible features, strong contrast between light and dark cloud bands is notably absent, as are bright and dark spots.
The eye is drawn to a bright wedge near the lower-left limb (apparent edge) of the planet. That wedge falls in a latitude band that borders a darker latitude band a little closer to the pole. Viewing the limb of the planet in ultraviolet light allows scientists to study the high part of the atmosphere (the stratosphere). Scientists can discern from this image that the stratosphere in this latitude band is relatively pure hydrogen and helium and contains very little of the stratospheric haze that causes darkening closer to the pole.
This view was taken with the Cassini spacecraft narrow angle camera on July 21, 2004, at a distance of 6.4 million kilometers (4 million miles) from Saturn. The image scale is 38 kilometers (23 miles) per pixel. The image was taken using a spectral filter centered at 298 nanometers, and reveals different details in the gas giant's atmosphere than those seen in longer wavelengths. Contrast was slightly enhanced to bring out features in the atmosphere.
Bright streaks adorn the face of densely cratered Rhea, Saturn's second largest moon. The lit terrain seen here is on the leading hemisphere of Rhea (1,528 kilometers, or 949 miles across). North ...
Resplendent Rhea
Presented here is a cartographic map sheet which forms a high-resolution Mimas atlas, a project of the Cassini Imaging Team. Mimas, as imaged by the Voyager spacecraft in the early 1980s, has a ...
The Mimas Atlas (2008)
The Cassini spacecraft peers through the fine, smoke-sized ice particles of Saturn's F ring toward the cratered face of Mimas. The F ring's core, which contains significantly larger particles, is d...
A Wisp of Smoke
The Cassini spacecraft has beamed back a new, more detailed image of smog-enshrouded Titan.
Through the Haze
This image of asteroid Vesta from NASA's Dawn spacecraft shows an old, very degraded crater that is almost completely filled with regolith. Regolith is the fine-grained material that covers most of...
An Old Crater Almost Completely Filled with Regolith
During a close flyby of Titan on March 31, 2005, Cassini's cameras got their best view to date of the region east of the bright Xanadu Region. This mosaic consists of several frames taken by the na...
Titan Mosaic - East of Xanadu
A swing high above Saturn by NASA's Cassini spacecraft revealed this stately view of the golden-hued planet and its main rings.
Jewel of the Solar System
This raw image of Saturn's moon Enceladus was taken by NASA's Cassini spacecraft on Dec. 20, 2010. The spacecraft was approximately 158,000 kilometers (98,000 miles) away from Enceladus. Image cre...
Dark Moon, Bright Spray
Numerous linear crater chains on Ceres dominate this image from NASA's Dawn spacecraft, which is centered at approximately 20 degrees north latitude, 198 degrees east longitude.
This image from NASA's Dawn spacecraft taken on June 13, 2016, shows terrain at the equator of Ceres. The image is centered at 0 degrees latitude, 291 degrees east longitude.
Ithaca Chasma is one of the two most prominent features on Saturn's moon Tethys; the other is the gigantic crater Odysseus. Ithaca Chasma is visible near the moon's lower right limb in this image, ...
Sintana Crater is seen on the left side of this image of Ceres from NASA's Dawn spacercraft. The crater's central peak casts a shadow over its western flank. At lower right, the rim of Darzamat pee...
This image of Aricia AV-L-11, from the atlas of the giant asteroid Vesta, was created from images taken as NASA's Dawn mission flew around the object, also known as a protoplanet.
Aricia AV-L-11
The Cassini spacecraft passed within a cosmic stone's throw of Telesto in October, 2005 capturing this shot of the tiny Trojan moon. Telesto (24 kilometers, or 15 miles across) appears to be mantl...
Smooth Surface of Telesto
Bold Saturn August 19, 2004 Full-Res: PIA06423 Saturn's atmosphere is prominently shown with th...
Bold Saturn
Diverse cloud forms shift and spin in the far northern reaches of Saturn. The image was taken with the Cassini spacecraft wide-angle camera on Feb. 18, 2008 using a spectral filter sensitive to wa...
The Turbulent North
Set starkly against the blackness of space are the F ring's delicate strands which are periodically gored by its shepherding moon, Prometheus. Prometheus (86 kilometers, or 53 miles across) and Pa...
Fragile F Ring
NASA's Dawn spacecraft in thermal vacuum chamber.
Dawn Spacecraft in Thermal Vacuum Chamber
The range of features to be found in Saturn's C ring is seen in this Cassini image. Near the bottom of the frame is a narrow eccentric ringlet lying in a gap that researchers suspect may contain o...
Many Faces of the C Ring
This view of the asteroid 243 Ida is a mosaic of five image frames acquired by the Galileo spacecraft's solid-state imaging system at ranges of 3,057 to 3,821 kilometers (1,900 to 2,375 miles) on A...
Asteroid Ida - Five Frame Mosaic
This image shows examples of straighter, shorter, wider gullies that scientists on NASA's Dawn mission have found on the giant asteroid Vesta. The crater shown here is called Fonteia.
Straight Gullies in Fonteia
Comet ISON shows off its tail in this three-minute exposure taken on 19 Nov. 2013 at 6:10 a.m. EST, using a 14-inch telescope located at the Marshall Space Flight Center.
Comet ISON Streaks Toward the Sun
Images recorded by the European Space Agency's Huygens probe descent imager/spectral radiometer between 11 and 5 miles (17 and 8 kilometers) were assembled to produce this panoramic mosaic. The pro...
Titan's Surface
This Cerean crater, which is covered in ridges and steep slopes, called scarps, was captured by NASA's Dawn spacecraft on Dec. 23, 2015. These features likely resulted when the crater partly collap...
Crater with Scarps in LAMO


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Nestled in the foothills backing onto the majestic Rocky Mountains, Sundre is a welcoming community located along the scenic Cowboy Trail. Set on the Red Deer River, Sundre sports many beautiful trails and parks, perfect for an early morning jog or an afternoon picnic with the family. On top of the beautifully treed riverside setting of Sundre, the neighboring Rocky Mountains are only a short drive away, providing abundant nature and adventure based tourism attractions including, hiking, camping and white water rafting, facilitated by the more than one thousand RV lots located in and around Sundre. Easily accessed from larger centers like Red Deer and Calgary, thousands of visitors choose Sundre as their base for exploring all that the West Country has to offer.
After your round, reminisce over your wins while being pampered by a professional masseuse- completely unwind and allow yourself to drift off in a complete state of bliss with the aroma of essential oils. Located centrally in the upper village, at the Pine Inn, Pure Massage offers a wide variety of services including massages, wraps, hot stone, body treatments and spa packages.
Even though you really enjoyed the smooth ride that our new fleet of powered golf carts with Visage GPS technology had to offer; exploring a rougher terrain at rapid speeds on a different type of 4 wheeler does justify you holding onto the steering wheel a little tighter. Toby Creek Adventures' ATV tours access beautiful backcountry. Tours are comfortable scenic wilderness experiences that are suitable for all members of the family, all ages and experience levels.


MP Julian Huppert brushed up on the life-saving skills he learnt as a St John Ambulance volunteer during a training session at the Liberal Democrat Conference.
Julian joined other MPs to reinforce his support for a campaign by TV hardman, Vinnie Jones to teach hands-only CPR as an alternative to the kiss of life.
He was invited to try the technique of giving chest compressions "hard and fast" at least 100 times each minute until professional help arrives.
The campaign is run by the British Heart Foundation which set up the training at the Brighton conference.
Vinnie Jones starred in a television advert to actively promote hands-only CPR and a training film recorded by the actor was shown at the conference.
Julian said: "I learnt life-saving skills during my time with St John Ambulance and realised very quickly how important it is to act fast when a person collapses. It can literally mean the difference between life and death.


text:
set -e
echo ""
echo "Testing netCDF-4 test programs with valgrind..."

# These are my test programs.
list='simple_nc4_wr simple_nc4_rd simple_xy_nc4_wr '\
'simple_xy_nc4_rd '

for tst in $list; do
    echo ""
    cmd1="valgrind -q --error-exitcode=2 --leak-check=full ./$tst"
    echo "$cmd1:"
    $cmd1
done

echo "SUCCESS!!!"

exit 0

redpajama_set_name: RedPajamaGithub


text:
Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome
Saori Kitao, Akira Shimamoto, Makoto Goto, Robert W. Miller, William A. Smithson, Noralane Morey Lindor, Yasuhiro Furuichi
Rothmund-Thomson syndrome (RTS; also known as poikiloderma congenitale) is a rare, autosomal recessive genetic disorder characterized by abnormalities in skin and skeleton, juvenile cataracts, premature ageing and a predisposition to neoplasia. Cytogenetic studies indicate that cells from affected patients show genomic instability often associated with chromosomal rearrangements causing an acquired somatic mosaicism. The gene(s) responsible for RTS remains unknown. The genes responsible for Werner and Bloom syndromes (WRN and BLM, respectively) have been identified as homologues of Escherichia coli RecQ, which encodes a DNA helicase that unwinds double-stranded DNA into single-stranded DNAs. Other eukaryotic homologues thus far identified are human RECQL (refs 13,14), Saccharomyces cerevisiae SGS1 (refs 15,16) and Schizosaccharomyces pombe rqh1+ (ref. 17). We recently cloned two new human helicase genes, RECQL4 at 8q24.3 and RECQL5 at 17q25, which encode members of the RecQ helicase family. Here, we report that three RTS patients carried two types of compound heterozygous mutations in RECQL4. The fact that the mutated alleles were inherited from the parents in one affected family and were not found in ethnically matched controls suggests that mutation of RECQL4 at human chromosome 8q24.3 is responsible for at least some cases of RTS.
https://doi.org/10.1038/8788
Rothmund-Thomson Syndrome
Skin Abnormalities
DNA Helicases
Inborn Genetic Diseases
Mosaicism
Schizosaccharomyces
Single-Stranded DNA
Human Chromosomes
Kitao, S., Shimamoto, A., Goto, M., Miller, R. W., Smithson, W. A., Lindor, N. M., & Furuichi, Y. (1999). Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome. Nature Genetics, 22(1), 82-84. https://doi.org/10.1038/8788
Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome. / Kitao, Saori; Shimamoto, Akira; Goto, Makoto; Miller, Robert W.; Smithson, William A.; Lindor, Noralane Morey; Furuichi, Yasuhiro.
In: Nature Genetics, Vol. 22, No. 1, 05.1999, p. 82-84.
Kitao, S, Shimamoto, A, Goto, M, Miller, RW, Smithson, WA, Lindor, NM & Furuichi, Y 1999, 'Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome', Nature Genetics, vol. 22, no. 1, pp. 82-84. https://doi.org/10.1038/8788
Kitao S, Shimamoto A, Goto M, Miller RW, Smithson WA, Lindor NM et al. Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome. Nature Genetics. 1999 May;22(1):82-84. https://doi.org/10.1038/8788
Kitao, Saori ; Shimamoto, Akira ; Goto, Makoto ; Miller, Robert W. ; Smithson, William A. ; Lindor, Noralane Morey ; Furuichi, Yasuhiro. / Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome. In: Nature Genetics. 1999 ; Vol. 22, No. 1. pp. 82-84.
@article{cfaf33eae37d47e89e77c56540650dfe,
title = "Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome",
abstract = "Rothmund-Thomson syndrome (RTS; also known as poikiloderma congenitale) is a rare, autosomal recessive genetic disorder characterized by abnormalities in skin and skeleton, juvenile cataracts, premature ageing and a predisposition to neoplasia. Cytogenetic studies indicate that cells from affected patients show genomic instability often associated with chromosomal rearrangements causing an acquired somatic mosaicism. The gene(s) responsible for RTS remains unknown. The genes responsible for Werner and Bloom syndromes (WRN and BLM, respectively) have been identified as homologues of Escherichia coli RecQ, which encodes a DNA helicase that unwinds double-stranded DNA into single-stranded DNAs. Other eukaryotic homologues thus far identified are human RECQL (refs 13,14), Saccharomyces cerevisiae SGS1 (refs 15,16) and Schizosaccharomyces pombe rqh1+ (ref. 17). We recently cloned two new human helicase genes, RECQL4 at 8q24.3 and RECQL5 at 17q25, which encode members of the RecQ helicase family. Here, we report that three RTS patients carried two types of compound heterozygous mutations in RECQL4. The fact that the mutated alleles were inherited from the parents in one affected family and were not found in ethnically matched controls suggests that mutation of RECQL4 at human chromosome 8q24.3 is responsible for at least some cases of RTS.",
author = "Saori Kitao and Akira Shimamoto and Makoto Goto and Miller, {Robert W.} and Smithson, {William A.} and Lindor, {Noralane Morey} and Yasuhiro Furuichi",
doi = "10.1038/8788",
T1 - Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome
AU - Kitao, Saori
AU - Shimamoto, Akira
AU - Goto, Makoto
AU - Miller, Robert W.
AU - Smithson, William A.
AU - Furuichi, Yasuhiro
N2 - Rothmund-Thomson syndrome (RTS; also known as poikiloderma congenitale) is a rare, autosomal recessive genetic disorder characterized by abnormalities in skin and skeleton, juvenile cataracts, premature ageing and a predisposition to neoplasia. Cytogenetic studies indicate that cells from affected patients show genomic instability often associated with chromosomal rearrangements causing an acquired somatic mosaicism. The gene(s) responsible for RTS remains unknown. The genes responsible for Werner and Bloom syndromes (WRN and BLM, respectively) have been identified as homologues of Escherichia coli RecQ, which encodes a DNA helicase that unwinds double-stranded DNA into single-stranded DNAs. Other eukaryotic homologues thus far identified are human RECQL (refs 13,14), Saccharomyces cerevisiae SGS1 (refs 15,16) and Schizosaccharomyces pombe rqh1+ (ref. 17). We recently cloned two new human helicase genes, RECQL4 at 8q24.3 and RECQL5 at 17q25, which encode members of the RecQ helicase family. Here, we report that three RTS patients carried two types of compound heterozygous mutations in RECQL4. The fact that the mutated alleles were inherited from the parents in one affected family and were not found in ethnically matched controls suggests that mutation of RECQL4 at human chromosome 8q24.3 is responsible for at least some cases of RTS.
AB - Rothmund-Thomson syndrome (RTS; also known as poikiloderma congenitale) is a rare, autosomal recessive genetic disorder characterized by abnormalities in skin and skeleton, juvenile cataracts, premature ageing and a predisposition to neoplasia. Cytogenetic studies indicate that cells from affected patients show genomic instability often associated with chromosomal rearrangements causing an acquired somatic mosaicism. The gene(s) responsible for RTS remains unknown. The genes responsible for Werner and Bloom syndromes (WRN and BLM, respectively) have been identified as homologues of Escherichia coli RecQ, which encodes a DNA helicase that unwinds double-stranded DNA into single-stranded DNAs. Other eukaryotic homologues thus far identified are human RECQL (refs 13,14), Saccharomyces cerevisiae SGS1 (refs 15,16) and Schizosaccharomyces pombe rqh1+ (ref. 17). We recently cloned two new human helicase genes, RECQL4 at 8q24.3 and RECQL5 at 17q25, which encode members of the RecQ helicase family. Here, we report that three RTS patients carried two types of compound heterozygous mutations in RECQL4. The fact that the mutated alleles were inherited from the parents in one affected family and were not found in ethnically matched controls suggests that mutation of RECQL4 at human chromosome 8q24.3 is responsible for at least some cases of RTS.
U2 - 10.1038/8788
DO - 10.1038/8788
10.1038/8788


text:
Digital Pathology Today is your podcast all about the world of digital pathology. Each week, we talk with industry leaders, key academics, top pathologists and more to discover the past, present and future of digital pathology.
KEY AREAS OF SERVICE
Provide news, information and analysis about the state of digital pathology
Examine digital pathology's past, present and future
Engage key leaders in digital pathology to discuss topics of interest to our listeners
Each episode of Digital Pathology Today will provide insight and information about the state of digital pathology from top leaders in the field.
Confirmed guests include:
"History of Digital Pathology"
Liron Pantanowitz, MBBCh
Director, Anatomic Pathology
"The State of Digital Pathology Regulation"
Joe Lennerz, MD, PhD
Medical Director, Center for Integrated Diagnostics
Co-Founder; Alliance for Digital Pathology
"The Intersection of Precision Medicine and Digital Pathology"
Anthony Magliocco, MD
Protean BioDiagnostics
"Artificial Intelligence in Digital Pathology"
Ajit Singh, PhD
Managing Director and General Partner
Artiman Ventures
Adjunct Professor; Stanford University Medical Center
"Remote diagnosis Using Digital Pathology"
Matthew Hanna, MD
Invited guests include:
Derek Welch, MD
PathGroup
Claire Weston
Reveal Biosciences
Greg Osmond, MD
Pathology Watch
Dan Milner, MD
American Society for Clinical Pathology Center for Global Health Team
Michael Isaacs
Director of informatics
Dr. Joseph Anderson is a consultant to early stage and mature companies in the digital pathology and molecular diagnostics space. Previously, he oversaw the clinical pathology group at Genomic Health as the Oncotype Dx Breast cancer assay grew to a volume of over half a million tests. He was also involved in the development of new products, including assays for DCIS, Colon Cancer and one of the first commercially available liquid biopsies. He served the College of American Pathologists on the Molecular Oncology Committee, with responsibility for proficiency testing in biomarkers for lung cancer in the United States and across the world and as member the House of Delegates representing California. He has served in several working groups and committees for the American Medical Association for CPT coding and reimbursement and assessment of new technologies such as next generation sequencing. Upon graduating from the University of Minnesota Medical School, he completed residency in Anatomic and Clinical Pathology at Rush University, fellowship in Oncologic Pathology at Fox Chase Cancer Center and post-doctoral training in Molecular diagnostics at UCSF. He initially worked in private practice, credentialed at 17 various hospitals and surgery centers. More details at: https://www.linkedin.com/in/joseph-anderson-md-b447b3/
Danny Schreiber is an award-winning journalist with over 25 years' experience in broadcast and print. He has worked at news operation KTTV and KTLA, where he won his Emmy award, in addition to Crain Communications where he led the team behind Crain's NewsPro publication. In addition, he has worked with Crain's Modern Health Care, the Association of Health Care Journalists, National Association of Science Writer, National Academy of Television Arts and Sciences, and the Society of Environmental Journalists.
More details at: https://www.linkedin.com/in/danny-schreiber-27632910/
Email: digitalpathologytoday@gmail.com
Web: www.digitalpathologytoday.com
562 University Drive, Unit 3


text:
The Sound Room
Studio Tickets
Berks Country Fest
The Sessions Archive
Listen to WEEU
Search Results for: grace
Posted on February 2, 2017 by WPsoundroom_Admin - Country, Pop, The Sessions
Stephanie Grace performs in The Sound Room at WEEU, 830 AM in Reading, PA.
From Stephanie's website:
In both miles and metaphors, a 12-hour drive from Douglassville, Pennsylvania to Nashville is a considerable distance. With her blossoming career as an ascending artist, it is an inspiring journey that Stephanie Grace knows well.
A songwriter with something essential to say, a gifted singer and a charismatic live performer who has opened shows for platinum artists like Taylor Swift, Scotty McCreery, John Michael Montgomery, Josh Turner, and The Charlie Daniels Band.
Now 20, and already a veteran of national radio promotional tours and imposing concert stages, it is difficult to imagine that Stephanie could be overwhelmed by anything. "It's all an act!" she laughs. "Growing up, I never had confidence. I was super awkward. Singing brought me out of that, but to this day I still get nervous before I sing. Then the second the song starts it's like, 'I've got this.' It's a drastic change. I get onstage and this explosion occurs."
Posted on March 13, 2019 by Jeremy Drey - Classical, Folk, Front Page Feature, Music, The Sessions
Seasons performs live in The Sound Room at WEEU, 830 AM in Reading, PA. Set includes "The Goat on the Roof" at 0:00, "Get My Pay" at 5:23, "Sea in My Veins" at 8:50 and "March Jigs" at 11:56
Seasons, a Celtic ensemble, features Peter Winter Lee on hammer dulcimer, Mary-Grace Autumn Lee on hammer dulcimer and drums, Mary-Kate Spring Lee on harp, and Mary-Clare Chun Lee on violin. The Sound Room is a project of Reading Eagle, WEEU830AM and Pretzel City Productions
Arrowhead Jazz Band
Posted on September 7, 2017 by WPsoundroom_Admin - Jazz, The Sessions
The Arrowhead Jazz Band performs live in The Sound Room at WEEU, 830 AM in Reading, PA. Set includes "Saint James Infirmary" at 0:00, "Mama Inez" at 5:10, and "Amazing Grace" at 8:56.
James Supra Band
Posted on April 6, 2017 by WPsoundroom_Admin - Blues, Rock, The Sessions
Berks Country Fest: An Americana Jamboree is proud to present the James Supra Band featuring Sarah Ayers on vocals, June 8 @ 6:00 pm – 7:30 pm at the beautiful Stone Terrace Tent at the Reading Public Museum, 500 Museum Rd, Reading, PA 19611 United States.
Harmonica or "harp" playing is well established with deep roots in the Americana music scene. Throwing back to its earliest use in countries like Germany, where it is also called the "mouth organ", skilled players of the instrument can add grace notes, solos, blues notes, bends and twists like no other musician can. When you add fabulous vocals and superb playing on guitar and bass, you arrive at where we're going with this show and you're on the James Supra Band's express train to concert fun.
Artists Sarah Ayers on vocals and James Supra on vocals and harmonica are joined by Lou Franco on acoustic guitars and vocals, and Mitch Shelly on acoustic upright bass. Sarah and James have been performing together unofficially some 10-plus years ago.
They continue to make great music and keep the crowds on their feet. In March of 2017, the James Supra Band was among the top nominees at the Lehigh Valley Music Awards, with nine nominations including Outstanding All-Around Performer, nominated both by fans and people who work in the music industry. He has won the top industry award two years in a row. James Supra also won Best Harmonica Player which made that the 18-consecutive time he won this award dating back to the award show's inception in 1999.
The hallmark of a performance by the James Supra Band with Sarah Ayers on vocals is 100% professionalism and audience engagement. Long-established fans come to be at the party and newcomers find themselves in what instantly feels like a familial event where all are welcome to dig into the fabulous buffet of music that's being served up by the band!
Tickets on sale online now at www.berkscountryfest.com
…or in person at:
Meadowood Music, 8521 Allentown Pike, Blandon, PA
Mail N' Ship 4 U, 96 Commerce Drive, Wyomissing, PA
Zeswitz, 100 Gibraltar Road, Exeter Township, PA
Sponsorships and licenses for Berks Country Fest: An Americana Jamboree can be obtained through Alicia Marinelli, amarinelli@pretzelcityproductions.com
Naelee Rae
Posted on February 1, 2017 by WPsoundroom_Admin - The Sessions
Naelee Rae performs in The Sound Room at WEEU, 830 AM in Reading, PA. Set includes "Give You the Sun" at 0:16, "Red Corvette" at 5:46, and "Shivers" at 11:02.
From her website:
Sweetly soaring vocals, graceful guitar-playing, and blending breezy melodies with boldly heart-on-sleeve lyrics characterize the music of Singer-Songwriter Naelee Rae.
At fourteen, Naelee started teaching herself how to play guitar and started writing songs right away. To date, her catalog has grown to over 200 songs.
Some places where Naelee has performed include:
– The Apollo, NYC
– Madison Square Garden, NYC
– Ashford & Simpson's Sugar Bar, NYC
– Bluebird Cafe, Nashville
– Musikfest, Bethlehem
– Many festivals, fairs, and restaurants
Larry Beaird from Beaird Music Group in Nashville recently stated, "Gonna be a star! That's my prediction."
We think so, too.
Kevin Neidig
Posted on December 21, 2016 by WPsoundroom_Admin - Folk, The Sessions
Kevin Neidig performs live in The Sound Room at WEEU, 830 AM in Reading, PA. Set includes "The House Carpenter" at 0:00, "Boundary" at 6:42, and "Rain Down" at 10:24.
Extended Audio Session Below:
Rarely do you get in one musician the virtuosity of singer, instrumentalist and songwriter. Kevin brings all three with eloquent effortlessness:
The unexpected complexity, combined with graceful agility, are what grab you by the throat, compelling you to listen into the wee hours. Kevin possesses an otherworldly ear and literal sleight of hand. Watching his nimble fingers execute a fretboard is like bearing witness to a spider weaving geometry into form. He manages to project a kind of tenderness clad in power, by turns exuding mystery, exuberance and wit.
From first note, you notice honed, flexible vocals, at once at ease with old-as-the-hills bluegrass as the latest pop number on the radio. There's authenticity underlying all the flow, and a comfort level with an impressive range – high and soulful to deep and baleful. Clear and powerfully emotive, Kevin's voice commands you to listen time and again as you marvel at how your soul is stirred with each play.
Kevin's approach never fails to present a different perspective – lyrically and musically. With his use of intricate timing, ingenuity with keys and tempos, and a dizzying contortion of chords, it's easy to understand why other musicians clamor to play his compositions for the thrill and sheer workout of it. He delivers impeccably crafted, hand-hewn tunes – a perfect turn of word here, transforming melodies there – lush, tuneful journeys not to be missed.
I've been described as a singer-songwriter and maestro of guitar, banjo, mandolin (I love anything with strings), influenced by Darrell Scott, Tim O'Brien, Sam Bush, Bela Fleck and Tony Rice – heroes one and all. I can get eclectic, too – doing the occasional metal tune, Foo Fighters, Allman Brothers Band, etc. Times change, though, and I'm not sure this description fits me anymore.
A person of considerable influence in my life recently described the tunes on my new solo CD as "Music of a New Era" and this feels right to me. Maybe it's because I'm now working with infusing intention into my music, the results of which feel like something altogether my own, or more "me" than anything else I've created musically. After studying under Grammy-nominated Sound Master Jonathan Goldman, I feel I've discovered a whole new way of working with music and sound, to the point where one of my sidelines involves working with sound in a healing capacity. I call it Sonic Reiki.
As performances and venues go, I was proud to perform, as part of Voxology, at the 2002 Salt Lake Winter Olympics and to open for such renowned acts as Doc Watson, Peter Rowan, Tom Paxton and the Alison Brown Quartet. I've enjoyed playing numerous gigs at colleges and universities, including Bucknell, Penn State and Cornell, to name a few, and just about every festival a stick can be shaken at from Arkansas to New York, such as Ohio's Funk-N-Groove Music Spectacular, Spoutwood Farm's Fairie Festival and Harrisburg's Kipona Arts Festival.
As for bragging rights, I have a nice collection of awards from the Deer Creek Fiddler's Convention in Westminster, MD, having won first place in the Male Vocal and Old-Time Banjo contests and four first place prizes in the Guitar competition. Another pride and joy of mine is the Neidig Guitar Studio, established 17 years ago in Mechanicsburg, PA, where I teach guitar and mandolin to a roster of talented and inspiring students.
If you have a question for The Sound Room team please contact us here.
Velvet Shelter
Dick Boak
Andrew Pauls
© 2019 The Sound Room.


The Appalachian Trail Conservancy (ATC) hosted neighbors and partners of the Great Barrington Trails and Greenways Alliance on July 24 at the ATC Kellogg Conservation Center in celebration of the successful 2009 A. T. Community Partners program. This event served as a big 'thank you' to the many volunteers, organizations, and businesses that have gone the extra mile to make Great Barrington and its surrounding areas a more hike, bike, and walk-friendly place.
Organizations in attendance included: The Great Barrington Land Conservancy, The Sheffield Land Trust, The Upper Housatonic Valley National Heritage Area, the Appalachian Mountain Club and the Berkshire Chapter of the Mass. A.T. Committee.
The evening began with a hike on the A.T. to the Jug End Lookout for a fantastic northward view of the Housatonic River Valley in Southern Berkshire County.
Following the hike, attendees enjoyed a picnic and presentation of the A.T. Community Partner program successes in 2009, including guided hikes, tales from the trail program, A.T. documentary screening, trail building work trips, and a young interviewer series involving students interviewing A.T. thru hikers.
Great Barrington and the ATC are pleased with the progress of this program which has strengthened the community's enjoyment and stewardship of many natural resource areas, including their own special segment of the A.T. Partners in the program hope that these connections enhance the dedication and vision that will sustain South Berkshire County as an enjoyable outdoor destination.


Experience the pristine lakes on Fraser Island.
Discover some of the most pristine lakes in Australia on Fraser Island.
One of the most scenic islands in the world, it should come as no surprise that Fraser Island was awarded a Heritage Status. Boasting marvelous fauna and flora, this island is known for its white silica beaches, sand dunes and endless stretches of rainforests. With a mild climate and sunlight that lasts virtually all year long, Fraser Island is additionally reputed for its wonderfully refreshing lakes.
In fact, Fraser Island has more than 100 freshwater, perched and window lakes to delight tourists of just about any age. While jet skis and speedboats are banned, most of these lakes are equipped with camping accessories and amenities.
One of Fraser Island's most popular lakes, Lake McKenzie is found on east of Kingfisher Resort in the Great Sandy National Park.
This freshwater lake is green colored and has a maximum depth of 12 meters. One of the most sought-after camping spots, Lake McKenzie is a perched lake that measures approximately 930 metres wide and 1200 metres long. With a hectare area of approximately 150, this lake is surrounded by white silica sand, ideal for a relaxing camping session. Tourists visiting Fraser Island will be glad to learn that the lake water is so clear and pure that it is actually inhabitable for quite a few species.
Best of all, visitors will be able to enjoy different complimentary camping facilities that have been set up for them, such as barbecues and toilets along with picnic an camping areas.
Located on Fraser Island, Lake Wabby has over 13 species of fish, which is why it is such a popular camping and fishing spot.
Both a barrage and window lake, lake Wabby has an important cultural significance to the Butchulla tribe. In fact, a century ago, this lake was only accessible to men belonging to the tribe. With a maximum depth of 39 feet, this lake offers plenty of sunshine where you can dry off after a refreshing dip in the gloriously cool water.
Fraser Island's Lake Wabby has quite a few facilities for anyone who wants to enjoy a nice family picnic or spend a few days by the lakeside. For example, tourists will be able to make the most out of the walk-in camping area and restrooms. Additionally, several walking tracks have been installed from the parking lot and around the lake. A lookout point is also included near Lake Wabby on Fraser Island.
Hailed as a paradise for anyone who wants to get lost in nature's lush embrace, Lake Allom is one of Fraser Island most prized jewel.
With cool, fresh water and plenty of sunlight, this lake is found north of the world-famous Woralie Track. Abundant in nature, this Fraser Island lake is backed by the Department of National Parks, Recreation, Sport and Racing Government, which means that it comes with a variety of facilities to make your camping trip more enjoyable and comfortable.
Lake Allom is particularly ideal to anyone who wants to spot turtles or drive through the picturesque road that leads to the lake.


text:
Fiddler on the Roof (film)
Fiddler on the Roof is a musical with music by Jerry Bock, lyrics by Sheldon Harnick, and book by Joseph Stein, set in the Pale of Settlement of Imperial Russia in 1905. It is based on Tevye and his Daughters (or Tevye the Dairyman) and other tales by Sholem Aleichem. The story centers on Tevye, the father of five daughters, and his attempts to maintain his Jewish religious and cultural traditions as outside influences encroach upon the family's lives. He must cope both with the strong-willed actions of his three older daughters, who wish to marry for love – each one's choice of a husband moves further away from the customs of his faith – and with the edict of the Tsar that evicts the Jews from their village.
The original Broadway production of the show, which opened in 1964, had the first musical theatre run in history to surpass 3,000 performances. Fiddler held the record for the longest-running Broadway musical for almost 10 years until Grease surpassed its run. It remains Broadway's sixteenth longest-running show in history. The production was extraordinarily profitable and highly acclaimed. It won nine Tony Awards, including Best Musical, score, book, direction and choreography. It spawned four Broadway revivals and a highly successful 1971 film adaptation, and the show has enjoyed enduring international popularity. It is also a very popular choice for school and community productions.
This page contains text from Wikipedia, the Free Encyclopedia -	https://wn.com/Fiddler_on_the_Roof
Fiddler on the Roof is a 1971 American musical comedy-drama film produced and directed by Norman Jewison. It is an adaptation of the 1964 Broadway musical of the same name, with music composed by Jerry Bock, lyrics by Sheldon Harnick, and screenplay by Joseph Stein. The film won three Academy Awards, including one for arranger-conductor John Williams. It was nominated for several more, including Best Picture, Best Actor for Chaim Topol as Tevye, and Best Supporting Actor for Leonard Frey, who played Mottel Kamzoil the Tailor (both had originally acted in the musical; Topol as Tevye in the London production and Frey in a minor part as Mendel, the rabbi's son). The decision to cast Topol, instead of Zero Mostel, as Tevye was a somewhat controversial one, as the role had originated with Mostel and he had made it famous. Years later, Jewison explained that he felt Mostel's larger-than-life personality, while fine on stage, would cause film audiences to see him (i.e., Zero Mostel, the actor) rather than the character of Tevye.
This page contains text from Wikipedia, the Free Encyclopedia -	https://wn.com/Fiddler_on_the_Roof_(film)
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Fiddler On The Roof, Fiddler On The Roof
Matchmaker, Fiddler On The Roof
Fiddler On The Roof, John Williams
Golde..."
(Golde)
Do I what?
(Tevye)
Do I love you?
With our daughters getting married
And this trouble in the town
You're upset, you're worn out
Go inside, go lie down!
Maybe it's indigestion
"Golde I'm asking you a question..."
You're a fool
"I know..."
But do you love me?
For twenty-five years I've washed your clothes
Cooked your meals, cleaned your house
Given you children, milked the cow
After twenty-five years, why talk about love right now?
Golde, The first time I met you
Was on our wedding day
I was scared
I was shy
I was nervous
So was I
But my father and my mother
Said we'd learn to love each other
And now I'm asking, Golde
I'm your wife
Do I love him?
For twenty-five years I've lived with him
Fought with him, starved with him
Twenty-five years my bed is his
If that's not love, what is?
Then you love me?
I suppose I do
And I suppose I love you too
(Both)
It doesn't change a thing
But even so
After twenty-five years
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Man sets fire to Japanese cartoon studio killing 33
Grand Forks Herald 19 Jul 2019
TOKYO -- A man shouted "Die!" as he sprayed a flammable liquid all over an animation studio in Japan on Thursday, July 18, and set the building on fire, killing 33 people as some victims collapsed in a desperate bid to reach the roof ... Many bodies were found on the top ......
Rule violations delayed nod, Kerala government tells high court
After pointing out the defects, the affidavit said, "From the narration of the above facts, it is evident that there was laches and violation of building rules on the part of the applicant ... The concrete pillars and concrete roof envisaged in the approved plan was changed into steel pillars and truss roof ... Download The Times of Indiafor Latest ....


FTP (File Transfer Protocol) Create FTP credentials. You must first create FTP credentials through your hosting provider. Go to FileZilla, also known as WordPress source editor, and enter your FTP host, username and password. You can use the Code Snippets plugin. Code Snippets plugin is a great way to add custom code to WordPress pages and is easier than creating your own plugin.
What is the best way to customize WordPress code?
WordPress pages are created by folks every workday. This means they download WordPress, setup it, and use a topic exactly as it was created. While you can achieve a great deal by using the right topic and plugin, there might still be a period when you realize that you have to get yourself into the code and put a few words in yourself.
Adding user-defined code to your WordPress page is the best way to do this, depending on a wide range of considerations. If so, don't include user-defined code in the subject matter file, says Erich Boileau, owner of Gaijin LLC, a web designer. "Once you upgrade the cores, plugins or designs, your changes will be deleted," he says.
So if you can't change the code directly in the theme's data sets, what should you do? Brandon Howard, proprietor of All My Web Needs, a WordPress web designing firm, says All My Web Needs allows you to create a sub site code to append to the features. phone book without having to worry about loosing your changes once you have downloaded WordPress Core or WordPress Topic Upgrades.
In addition, with sub topics, you can use "hooks that are WordPress dependent, and topics [...] to paste your code," he says. If you' re not sure what a kid topic is, let me tell you. It' essentially a sub-theme to your primary topic installation. Indeed, all you need to do is FTP your site and make a directory (something like Topic Name Picture will work) and then make a template. This is a template corresponding to the directory name.
Retracts information from the higher-level theme's own style sheet. All you need to do is enable the subtitle design in your dashboard. We' ve actually written about how you can extensively build your own children's topic some time ago, so you should consider this when deciding how you want to include customized code on your website.
So if you aren't very experienced in working with the WordPress frontend, but still want to make some user-defined code optimizations, you should use a plug-in that allows you to add code to strategically placed parts of your website. Scott Chow of The Blog Starter says that using a plug-in will reduce "the likelihood of something being erased accidentally".
First: Add headers and footers. With this plug-in you can add code to the headers or footers of your website. His second recommended plug-in is Global Content Blocks. You can use this plug-in to add code to articles and store these code excerpts for later use. Natalia Chriss, another development I talked to, has an extra plug-in suggestion.
It' titled Code Insert Manager and is perfect for attaching code to Google Analytics, Aweber and GetResponse as well. If you want to remodel a website but keep the same features - or just want to put code somewhere on your website - you can build a plug-in to use it.
"I' m creating a site-specific function plug-in for user-defined code rather than integrating it into the theme's features. I' m creating a phone file," says Adam Smith, IT Director at Marketing Mojo. "That' s what makes WordPress different from design," he says, pointing out that this is most often the case when you use someone else' s designs, and not the ones you created yourself.
Smith uses this plug-in for user-defined functions to include typical user-defined mail type, shortcuts, customizations to the WordPress administrator, and other changes he deems necessary. "In many cases, we create user-defined plug-ins with only 10-20 rows of code just because we want a small thing to be added, and it's important that the thing stay in place even if the topic is changed," he says.
We' ve just talked about what to do if you want to include customized code on a topic you've been downloading for free or buying at a special interest store. What if you had done it yourself? Once you've rewritten your design from the ground up, "you can paste the code directly into the design," says Boileau, which would have a great side effect in improving the site's performance and effectiveness.
Simply open the features of your topic. If you want to make a small modification, a pdf should do. Yes, this methodology is valid both for those who use other people's topics and for those who use them. Creating a plug-in that accompanies your own topic has some neat benefits.
It not only makes it easier for you to turn certain site features on and off if you choose not to need them anymore, it also gives you the ability to get into plug-in programming. When you think that the code within the plug-in you create is beneficial to other programmers, "you can consider creating your own all-new plug-in and sending it to WordPress to help others," says Boileau.
If you are asked to include user-defined code on a WordPress site, you should do so: Build plug-ins to include advanced page features. It should help you build customized websites that remain exactly the way you want them to, no matter what new releases are made. Hopefully you now have a better grasp of how to apply user-defined code to your WordPress page and which methods work best in your present state.


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NBC Sets Awkwafina, Seth Meyers as Next SNL Hosts; Travis Scott, Paul Simon as Musical Guests
By Stephan Cho | September 27, 2018 | 5:25pm
Photos by Desiree Navarro/Getty, Dimitrios Kambouris/Getty Comedy News Saturday Night Live
NBC has set the hosts and musical guests of the next two episodes of SNL, and we're getting both total newcomers and long, long-time veterans.
This summer's Crazy Rich Asians and Ocean's 8 breakout Awkwafina is set to host the second episode of the season on Oct. 6, joined by first-time musical guest Travis Scott, who's set to embark on the Astroworld – Wish You Were Here tour in November.
For the third episode of the season, airing on Oct. 13, we have host Seth Meyers, who spent 13 seasons on the show and, of course, was "Weekend Update" anchor before his current Late Night gig. Musical guest Paul Simon will also join the 15-timers club with his appearance on the forthcoming episode, which has him celebrating his 77th birthday and promoting his 14th studio album, In the Blue Light.
The show's picks for the season premiere this coming weekend seemed a bit underwhelming, so it's good to hear that the following two weeks are a bit more up the show's usual alley. Now so long as the show stays clear of any particularly dicey Brett Kavanaugh jokes, we should be in for a good time.
awkwafina
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DIMEBAG Murderer's Mother Speaks Again: My Son's Killer Is A Hero
Chad Williamson of Marysville Journal-Tribune has issued the following report:
On the wall of Mary Clark's apartment in Marysville is a wooden picture frame containing odd-shaped pictures of her three boys' typical pictures of smiling children that a mother would cherish.
Carved above the pictures is the inscription "Children fill our lives with love, laughter, mischief and memories."
Prior to Dec. 8, Clark, a mother of three boys, ages 30, 27 and 25, had plenty of the first two intangibles listed on the frame. On that night, however, the latter two, although painfully understated, stepped into the forefront.
Clark's son, Nathan Gale, 25, who lived at 111 1/2 E. Fifth St., opened fire at the Alrosa Villa in Columbus during a heavy metal concert, killing a nationally-known guitarist and three other individuals before a Columbus police officer ended his life with a single shot.
"I was shocked that my son was gone, but the damage that he did to everyone else," Clark said. "My heart just goes out to them."
Clark is left with lingering doubts about failing to recognize her son's mental illness, the outrage of fans and families on a national level and the guilt of having purchased the gun used in the shootings.
Clark loved her son dearly. She said he was a typical young man for most of his childhood. He was good natured, enjoyed snowboarding and loved sports. He even played semi pro football for the Lima Thunder.
According to his mother, he had many friends, an image that later was reversed.
In his teenage years he had a battle with drugs but had apparently fought through the addiction and was pulling his life together. He had attended Benjamin Logan High School early in high school but later transferred to Marysville and attended the Ohio Hi-Point Career Center.
"I never covered for my children, though I love them deeply," Clark said.
Christmas was a happy time for Clark. Her family was together and the spirit of the holidays was in the air. Her son, Nathan, wearing his endearing thick glasses, was there taking part. He was a funny, peaceful boy, by his mother's account, and took care to help his mother with the holiday traditions. Each year Nathan, a hulk at 6 feet 3 inches and 260 pounds, would help his mother pack away the Christmas tree and decorations because his she was too short to get them into their storage spot.
Recent Christmases had been especially soothing for Clark, because her son was growing into a man. Nathan had turned his life around. He had kicked his drug habit and entered the United States Marine Corps.
"He wanted to do something more with his life," Clark said.
Clark said her son had an interest in target shooting at a Delaware County shooting range. Upon completing basic training in 2002, Nathan received a special Christmas present from his mother — a semi-automatic handgun. She said the present was meant to show her son how proud she was of his accomplishments.
"He was cleaned up," Clark said. "It was a reward for cleaning himself up."
What Clark and others did not know was that Nathan was hearing voices in his head. In 2003 the Marine Corps gave Nathan a medical discharge after diagnosing him with paranoid schizophrenia.
Clark said she and other family members did not know of her son's problem.
The Marines sent Nathan home with a prescription of pills and little else. Once he returned home, Gale turned into a loner. He was a darker person.
"They (the Marines) said 'we don't have the money to help with this,'" Clark said.
During high school Gale developed an obsession for the heavy metal band PANTERA. Although Clark cannot remember if he ever saw the group perform a concert, Clark said her son did attend live heavy metal performances and took part in "mosh pits," which involve violent masses of bodies running into each other during such concerts. She remembered that during one such event, Gale came home with a black eye.
Though PANTERA split up, Gale remained fixated on its music. He dabbled in music, trying to play guitar but having little success, his mother said. He claimed at one point, prior to his diagnosis, that the band had stolen lyrics from him. He said the ideas in songs by PANTERA, which performed songs titled "Death Trap", "Clash with Reality" and "By Demons be Driven", were his own ideas and experiences.
Beyond that episode, Clark said, Gale never had a bad word to say about the band.
But on the night of Dec. 8, a deeply-hidden secret erupted from within Gale at the Alrosa Villa nightclub.
The group DAMAGEPLAN, comprised of two former members of PANTERA, including guitar legend "Dimebag" Darrell Abbott, took the stage that night. Gale was there. A short way into the first song he climbed onto the stage, made his way over to Abbott and shot him repeatedly with the gun that his mother had purchased.
He also used the weapon to kill three other people before Columbus Police Officer James D. Niggemeyer entered the club without backup and killed Gale, who was holding a hostage, with a single shotgun blast.
People across the country have hailed Niggemeyer as a hero. Clark said the man who killed her son is indeed a hero.
"He was doing his job," Clark said. "You don't know how many lives he saved with that shot."
Clark said she has purchased a card and intends to send a note to Niggemeyer.
"That's a horrible thing for him (Niggemeyer) to have to do," Clark said. "He was a hero — I agree with everyone on that."
Memories are all Mary Clark has left of her son.
Because of national media attention and fear of retribution, a private ceremony was held at an undisclosed funeral home after Gale was cremated. Though funerals are supposed to help the survivors deal with grief by accepting the condolences of friends, Clark and her family could not take the risk of opening the doors to the public.
Clark has read of threats against her family on the Internet. And, though the family has no relatives in the city, she knows of a local woman with the last name of Gale who has been threatened repeatedly over the phone.
"The mentality of some people is ridiculous," she said. "They think I should be shot with the same gun."
Clark said she has tried to keep a low profile since the shootings.
Immediately afterward, she packed a bag and stayed at a friend's house to avoid the media spotlight. Her phone rings repeatedly with requests for interviews.
She has tried to avoid local public places because she does not want to attract any attention. Though some locally have offered support and condolences, any attention brings her thoughts back to the events and her son. But even venturing out of town to eat dinner cannot give Clark an escape. Recently over a meal, a group at a nearby table was making jokes about the shooting.
"I know I'll have to hear things but it's not a joking matter," she said. "They don't know who they're sitting next too."
Clark said she intends to get back to work next week and hopes to settle back into a routine.
What stays with Clark is the guilt of having purchased a gun that was used to kill four innocent people. It was a simple token meant as a reward and it was used to end four lives.
"I'll pay for that one day," Clark said.
Since the shootings, Gale has found journals that her son used to keep.
The writings are somewhat free flowing, almost in a stream-of-consciousness manner. Topics are varied but the journals point to Gale's mental illness. He describes an inability to be able to hear his own thoughts.
"He just wanted something to break through to make him normal," Clark said. "I think he was searching for answers just as we are now."
Under the family photos on the picture frame on Clark's wall are a few more words: "Children make a life complete, cherish them forever."
Clark is left with a life that is less than complete. She shoulders some of the blame for the tragedy on Dec. 8 that ended five lives, including the life of one of her children. Through doubts about purchasing the weapon, Clark is left with a deeper regret about failing to recognize her son's mental illness. She said her son kept his struggles a secret.
She said he never confided in her about the voices in his head.
"He kept it very well under control around me," she said. "If he hadn't gone in the Marines, we may never have known."
Clark can't say if her son took the pills prescribed to him by the Marine Corps. She also cannot say if her son relapsed into drug use in the months leading up to the end of his life. Toxicology reports ordered by the police will paint a clearer picture on that issue.
Clark said many of the problems of young adults are filed away as drug addiction, when deeper causes could be the root. She noted that schizophrenia often manifests in the early adult years.
"You just don't blame everything on drugs," Clark said.
What Clark does know is that her son had a problem that wasn't fixed or controlled. She said her son never sought to use the mental health services offered in Union County — services that could have helped him calm the voices in his head.
"We all wonder why you can't help these people before it's too late," she said.
(Thanks: Jason Bodak)
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> Blog > Interesting Information > Type 1, Type 2, Type 3 ????
This post is to provide you with some useful information and to explain what the "Type" definitions are that VW has used for some many years.
From the very earliest days, Volkswagen has identified its various different models and designs by assigning them a series of Type designations. Originally they were only used within the VW organisation, but over the years they have become widely known and used by VW enthusiasts.
The Type designations really apply to air-cooled Volkswagens only. While the factory did apply Type designations to later water-cooled models, they are little known outside the VW organisation. Since 1980 VW has not referred to VW 'Types' at all, and model codes now form part of the 17-digit VIN. Modern VWs tend to be organised by 'platform' instead.
For this section, we will only consider Volkswagens made before 1980. For newer VWs, refer to the VIN listing page.
The British handed the VW factory back to the Germans in September 1949, the year the three former Allied zones were united to form the German Federal Republic. Former Opel director Heinz Nordhoff was appointed General Manager of the Volkswagenwerk.
Under German control, VW released two new Cabriolet models in 1949 alongside refinements and expansion of the sedan line-up. VW took the opportunity to reorganise the British model Type numbering system, and a new system was put in place. This saw the VW range divided into 4 basic types (eventually), with each type further divided into models described with three-digit numbers. This basic system lasted until the end of German air-cooled models and the introduction of the modern VIN system.
Within these four Volkswagen Types, the individual models were identified by a three-digit code – the first digit always being the Type number above. VW's first model lists for the Types 1 and 2 were drawn up in 1949 and 1950. They were reorganised and renumbered in 1966 for the 1967 model year, so there are two separate lists for each Type. After 1966, the first two digits of the Type number were used on the chassis number. Models were separated depending on whether they were Left or Right-Hand Drive.
Volkswagen water-cooled models of the early 1970s were also given similar-style Type numbers, and these are listed below. However, unlike the air-cooled models, these are not well known and hardly ever used, even by VW sales staff, mechanics and enthusiasts. VW Type numbers are generally only used when referring to air-cooled models.
While Type designations do show up in modern, post-1980 VIN codes, their importance has greatly diminished except for their use in spare parts codes. They often do not have any historical connection with previous Types. The T3 Transporter has a VIN type descriptor of '24' (pickups) or '25' (vans and buses) for example, and can still be said to be a Type 2. The T4 Transporter on the other hand, has a VIN descriptor of '70' and is thus not a 'Type 2' at all. For Australia the New Beetle is a '9C' and has no connection with the 'Type 1' (so it really isn't a Beetle). The first Polo was Type 86, but newer ones are 9N.
So while VW has an internal system for type designations, these are no longer used outside of Volkswagen. We don't refer to newer Golfs as Type 1G or Type 1H; they are Golf 2 or Golf 3.
For the record, here are some other VW model types used prior to the introduction of the VIN in 1980.


Et resume på Engelsk af bogen "The Potato People" af Angela Wright.
Opgaven stammer fra "Blue cat" som er en af folkeskolens engelsk bøger.
In the village Skullgoragh two boys once lived, called Sean and Patrick. Patrick was like a little brother to Sean. Patrick was unable to protect himself because he wasn't big and muscular like Sean. Sean was tall, and brave. Before the British came, and turned his families land over to lord Egham, he was a lord and owned all the land of Skullgoragh. The entire village relied on the potato harvest. So when the day came and the harvest failed they were all poor and starving. They had neither income nor food.


The Confluent Schema Registry often serves as the heart of a streaming platform, as it provides centralized management and storage of the schemas for an organization. One feature of the Schema Registry that deserves more attention is its ability to incorporate pluggable resource extensions.
Subject modes. For example, one might want to "freeze" a subject so that no further changes can be made.
A Schema Registry browser. This is a complete single-page application for managing and visualizing schemas in a web browser.
Along the way I will show how to use the KCache library that I introduced in my last post.
The first resource extension that I will demonstrate is one that provides support for subject modes. With this extension, a subject can be placed in "read-only" mode so that no further changes can be made to the subject. Also, an entire Schema Registry cluster can be placed in "read-only" mode. This may be useful, for example, when using Confluent Replicator to replicate Schema Registry from one Kafka cluster to another. If one wants to keep the two registries in sync, one could mark the Schema Registry that is the target of replication as "read-only".
The complete source code listing can be found here.
I haven't shown all the functionality of the Schema Registry browser, but it supports all the APIs that are available through REST, including creating schemas, retrieving schemas by ID, etc.


ROBO 3D Certified Print Packs include 20 unique models pre-installed on USB that can be used in Kitchens, Gardens, Bathrooms, and Offices.
ROBO 3D Certified Print Packs feature twenty, high quality, digital models that have been custom designed by the ROBO 3D team. With a wide variety to choose from, each print pack provides countless hours of 3D printing for hobbyists. The packs are designed to improve different decors at any home or office. They're saved in .STL file format; ready for either ROBO 3D or other 3rd party printers. The ROBO 3D Certified Print Packs are available in Garden, Kitchen, Bath, and Office. They're sold separately and pre-installed on USB for easy file transfer.
For the Garden print pack, choose from a wide range of outdoor-ready 3D prints that will decorate any yard.
The Kitchen print pack features both functional and aesthetic models.
Robo 3D's Bath print pack will not only update your décor, but also allow you to custom tailor your design using different color filaments.
The Office print pack will liven up your work atmosphere and help get you through the day.


If a person intends to observe a naafil fast, then he is invited to eat when visiting some relatives and he eats, is there any sin on him, or does he have to repeat that day so long as he intended to fast?.
1 – Muslim (1154) narrated that 'Aa'ishah (may Allaah be pleased with her) said: The Prophet (peace and blessings of Allaah be upon him) entered upon me one day and said: "Do you have anything (any food)?" We said, "No." He said, "Then I am fasting." Then he came to us another day and we said, "O Messenger of Allaah, we have been given some hays (a kind of food made from dates and ghee)." He said, "Show it to me, for I started the day fasting." Then he ate.
This clearly supports the view of al-Shaafa'i and those who agreed with him, that a naafil fast may be broken, and one may eat during the day and cancel the fast, because it is naafil, and the person has the choice whether to start it and continue it. Among those who were of this view are a number of the Sahaabah, Ahmad, Ishaaq and others, but all of them, and al-Shaafa'i too, are agreed that it is mustahabb to complete the fast. Abu Haneefah and Maalik said that it is not permissible to break the fast and doing so is a sin. This is also the view of al-Hasan al-Basri, Makhool and al-Nakh'i; they said that it is obligatory for the one who breaks the fast without an excuse to make it up. Ibn 'Abd al-Barr said: They were unanimously agreed that the one who has an excuse for breaking the fast does not have to make it up. And Allaah knows best.
2 – Ahmad (26353) narrated from Umm Haani' that the Messenger of Allaah (peace and blessings of Allaah be upon him) entered upon her and called for something to drink, and drank some, then he passed it to her and she drank some. She said: "O Messenger of Allaah, I was fasting." The Messenger of Allaah (peace and blessings of Allaah be upon him) said: "The one who is observing a voluntary fast is his own master; if he wishes he may (continue to) fast and if he wishes he may break his fast." Classed as saheeh by al-Albaani in Saheeh al-Jaami', 3854.
The ahaadeeth on this topic indicate that it is permissible for the one who is observing a voluntary fast to break it, especially if he is invited to eat by a Muslim.
3 – al-Bayhaqi narrated that Abu Sa'eed al-Khudri said: Some food was made for the Prophet (peace and blessings of Allaah be upon him) and when it was served a man said: "I am fasting." The Messenger of Allaah (peace and blessings of Allaah be upon him) said: "Your brother has invited you and make this effort for you. Break your fast and make it up later if you wish." Al-Haafiz said: Its isnaad is hasan.


If you wish to get a limited edition 30 day trial version of mSCADA/AR-SCADA/UNISEMS modules with a sample project and virtual tour or give your feedback or have any queries on our products and services, please fill the form below giving your official mail ID and your official URL. Alternatively you can write an e-mail to us at info@pramanj.com or pramanj2015@gmail.com from your official mail ID. We will be glad to help you.


Milwaukee, WI (September 9, 2017) – During the 52nd Annual Meeting & Course held in Philadelphia, Pennsylvania, September 6-9, the Scoliosis Research Society (SRS) announced the winners of the Russell A. Hibbs, John H. Moe & Louis A. Goldstein Awards. Named after pioneers in scoliosis surgery, the awards are given to the best basic research and best clinical research papers.
Nominees for the awards are selected by the Program Committee from the submitted 2017 abstracts for the IMAST and the SRS Annual Meeting. The nominees are invited to submit their paper's manuscript which is reviewed by the Program Committee. During the meeting, attendees vote for their favorite presentation via the SRS Annual Meeting app and the popular votes and manuscript scores are taken into consideration by the Program Committee, who select the final winners.


When the economy slowed in 2008, and consumers reduced grocery spending overall and shifted toward less expensive and private-label products, premium-brand tortilla chip maker Truco began looking for ways to help Kroger grow bagged snack category sales and profits while also strengthening sales of Truco's On The Border products. The company's focus was on how to give Kroger shoppers a high-quality branded tortilla chip option at a competitive price while working within the constraints of available shelf space and distribution.
Truco's pallet-based promotions have helped its grocery partner increase overall bagged snack dollar sales by 4.4% and gross margin by 2.6% in the past year.
During the same period, Truco has grown its own sales by 16.6% while also helping its grocery partner get more shoppers to purchase the category more frequently and with larger average basket sizes. Truco's pallet promotions drive an average 3.3 times lift in dollar sales in Truco products. Additionally, Truco achieves an average 115% sell-through on pallet programs, minimizing residual inventory and improving exit strategies.


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Every event we do is important. It doesn't matter if it's for 50 or 5,000 people. The goal is always the same; to bring people together through a great environment and great DJs and MCs who facilitate it all.
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