That red and black brooding piece by Siqueros could come up in nightmares ... Magnificent!
I'm impressed. I usually am when you post about art.
Cool range of stuff there, Grrrl. I'm naturally drawn to the Earth photograph, though the others are worth a look as well.
That's a cool collection of art. I was quite taken with the aerial photograph of the Lena river delta and I also followed the Andy Warhol article and Tina Modotti links. They say the past is another country, but I feel that those Tina Modotti photographs really provide glimpses into a whole 'nother world.
Life is much like a river, is it not? Rushing away from her mountain birth in tiny rills and cascades she rejoices in waterfalls and rapids. In maturity she slows growing wide and deep. At last the mighty river tangles herself among a thousand islands of memory on her reluctant approach to the sea.
I liked them all but that one stopped me in my tracks.
Wow1 Oh wow! Oh wow! What an amazing cache. I love them all - so different - so varied - and each a unique expression.
Akseli - I found you through a comment on Francis' blog. Welcome and thanks for topping by!
This is amazing. The Wyeths are utterly amazing.
Sandy - I was hoping someone would mention the Wyeths. I love the mood of the day he captured in all three.
I was oohing and ahhing over each of them ~ long-time Wyeth fan, and I love the puppeteer's hands. but that Warhol photo? fantastic. a fave. great find Gina. have a great weekend.
Gina, these are all so good that it is hard to single out just one for comment. Nice post.
Becky - so good to have you back!
Jack - glad you enjoyed the post!
Everyone - have a great weekend. I have a four-day starting right which I plan on enjoying thoroughly!
Okay... I'm going to take just one of these and see if I can describe what it does to me. "The Sweep"
This is a deceptively simple painting. Typical Wyeth, too, in the way so much of it is balanced perfectly, and the way he plucks this set of visual teeter totters out of the craziest slice of the middle of nowhere. It's not so much a painting of a thing or a place as it is a painting of the place AROUND or BETWEEN the things and places.
The horizon line just about cuts the painting in half. This is generally a no-no, and Wyeth deeply understands this. The half-way line is a sort of "bottom of the visual gravity well" "most obvious and boring spot" for the major dissector of a piece. And that is precisely why it plays such games with the shallow diagonal of the top of the wall, emphasized by the long pole on top, and the way the right hand end curves just a bit above the horizon line. The center line is such a strong pressure that it makes that little distortion on the right, the diagonal, and the ever-so-quiet S-curve of the whole top of the wall, MUCH more important than they would normally be in any other position. And that emphasis of the pole would not be anywhere near as strong without that glimpse of snow under it - which is o-so-nearly-but-not-quite in the middle of the painting - a sort of fulcrum or balancing point for the pole and the painting on the OTHER axis. Tension AND balance in both dimensions.
The stones are in the foreground - but somehow they seem to be like little miniature skies, and thus the big sky on top seems closer and more immediate than it otherwise might. It makes the foreground and background tussle with each other, even as everything seems so peaceful due the nearly windowpane like divisions on the surface plane.
And just try in your mind's eye changing the shape or placement of the large dark tree silhouette on the left, or the balancing darkness in the lower right. Any change you can picture seems to diminish the painting, or upset the balancing that makes the pole and the top of the wall the REASON for this image. Even the darkest stone in the wall is not an accident, nor can it be moved or changed without loss to the sum of the painting.
To me, this is what stands out in Wyeth's work as his particular voice, his particular genius. As much as his colors, textures, and subject matter are his own, for me it is these compositional tensions and balances making the pieces so peaceful and yet on the edge, like the stillness before something spontaneously shifts, or the pent up pressures of centuries, which are his real subjects, his real message.
And seeing studies he did prior to paintings provides many hints about the work he did to CREATE, not just find, these glimpses of balance and tension - these pecularily Wyeth compositions. The final painting is often much removed from the initial sketch or concept, and each drawing between brings more harmony and force into the mix, until you have the final statement, which is the most peaceful and more powerful of the series. He WORKED at these - they were't discovered; they were MADE. They weren't lying around him - his surroundings offered hints and then the paintings came out of his soul. You can't go looking for Wyeth's paintings in the Branywine Valley of Pennsylvania because they only exist on the paper, canvas, and masonite, the products not of his eyes, but of his inner vision.


Shed light on your promotion with this mini aluminum flashlight with claw hook keychain attachment. Flashlight features 3 ultra-bright LED bulbs and easy-to-use rubber push button on/off switch on end.
Prop 65 and CPSIA compliant. Price includes 1 location laser engraved imprint. Setup: $55. Repeat setup: $25. Every effort is made to produce the exact quantity requested, however; due to imprinting processes you may receive and be billed for 5% more or less than the quantity ordered.
Size: 2"L x 1/2" diam.


Another product of Bill Gates and Paul Allen. This version of BASIC was not loaded into RAM, leaving more memory available for programs.
To load Extended ROM BASIC – switch 2 up, switch 1 up (all others down).
AUX1 down. This will load Extended BASIC from Arduino memory into addresses 0xC000-0xFFFF and terminal will display MEMORY SIZE?
Enter capital "O" (for Okidata) and press Enter.
To load a program, first clear any program that may be in memory by typing "NEW" and press Enter.
Set the front panel switches 0-8 to the address of the program you want to load, with all other switches down.
Press AUX2 down, the program will start to load. When it's done, just type "RUN" and press Enter.
These programs can also be loaded when any other version of BASIC is running, including CP/M's MBASIC and 4k BASIC, but most will not run in 4k BASIC due to the limitations of the language.


text:
by Mary · Published December 23, 2022
We don't know about you, but we're always a little excited for a brand new calendar at the beginning of a new year. And we're always looking for ones that reflect our interests and passions…
by Bette Porter_LA · Published December 23, 2022
What could easily have been the most beautiful, heartwarming, goosebumps reunion, in an endless amount of better and more believable scenarios, was now presented to us in a cringeworthy, disposable, romcom dream…
by Bette Porter_LA · Published December 5, 2022 · Last modified December 6, 2022
For season 3 of The L Word, showrunner Marja Lewis-Ryan had the option to choose either of the two endings to this saying: "all good things come to those who wait" or "all good things must come to an end". However, she decided she's not the choosing type and, much to the dismay and rage of all the loyal fans, she ran with both options.
The L Word / The L Word Generation Q / Videos
by Mary · Published December 4, 2022 · Last modified December 5, 2022
Advocate Today Interview | Laurel Holloman "The L Word: Generation Q"
"I want to say thank you to all the fans, because we really wouldn't be back there without them, you know, and I'm so happy that people love this relationship of Bette and Tina as much as Jen and I do, as much as we love these characters and love this family…"
by Bette Porter_LA · Published December 2, 2022
How low can you go
I won't beat around the bush here: it was the most painful episode of The L Word (OG and Gen Q) I ever had to watch. Deliberate choice of the words "had to", as I really felt I should write about it, even though after seeing the very first scene in the ambulance already made me want to turn off my TV. But hey, I'm a tough cookie, so just shouting at my device when events really became too far stretched and ridiculous to even be remotely believable, helped me through.
The New Year is just around the corner. For many people a time to reflect and make New Year's resolutions. So did these ladies #waybackwhen
by Mary · Published December 9, 2022 · Last modified December 11, 2022
Here's the thing. It's been way longer than nine months, and there's no sign that you're moving on. But, hey, we're glad you're still here – and we love that you have hope. We're still here, too. And we're just as curious as you are to see how this story plays out.
We wrote it. We shot it. We loved it. But the network didn't. It was the rare instance in which we had a creative disagreement. Our executives simply felt that it was too soon for us to be spoofing ourselves. They felt that it was something to be attempted in a third or a fourth season, but not at the end of the first season, when the audience was still bonding with these characters.
Back in the day ourchart.com was groundbreaking. It "invented" interconnectivity even before Facebook took the stage. A website where LGBTQ+ could meet up with each other, share stories, discuss their favorite show, get links...
by Mary · Published November 25, 2022
"I want to be in a grand, historic, iconic love story"
I gave it to the universe and it handed me back my request in an even more extraordinary package of playing in an iconic, wonderful, lesbian love story. And it was fantastic. It was more than I even knew what to ask for. And I'm incredibly grateful…
The L Word / The L Word Generation Q / Videos / Way Back When
by Mary · Published November 19, 2022 · Last modified December 9, 2022
All about our love…
After all this time, as a small tribute to this iconic couple, a "throwback":
Those who were there for it will remember the elated excitement the morning these screeners came out just a few hours before the last episode "Last Word" aired (March 8th, 2009), with the song that was originally meant for the last Tibette love scene (All about our love, by Sade).
Promotional Photos / The L Word Generation Q
by Mary · Published November 9, 2022 · Last modified November 21, 2022
The L Word: Generation Q, Episode 3.02 – "Los Angeles Traffic" Promotional Photos
Bette and Shane break new ground with Tina and Tess, respectively, but old habits come back to bite them. Sparks fly with Alice's latest prospect until an unexpected revelation, while Angie heals her heartbreak with a new flame. Meanwhile, Finley competes for Maribel's favor until Maribel drops a bomb about Sophie that threatens to tear them apart, and Dani puts hurt feelings aside for Gigi, but is it too late?
by Bette Porter_LA · Published November 3, 2022 · Last modified November 21, 2022
L for Longevity
We were talking about longevity, a word that keeps coming up when the desired storylines for The L Word are being discussed on social media. Longevity in lesbian relationships specifically, because representation matters, and as yet there are far too few (if any) long lasting lesbian relationships portrayed in TV-shows.
The L Word Generation Q / Videos
by Mary · Published October 29, 2022 · Last modified November 27, 2022
The L Word: Generation Q – Find the One
So many of us struggle. But our time here is limited. Reminds me not to waste another second…
Bette Porter
The L Word: Generation Q, Episode 3.01 – "Last Year" Promotional Photos
Bette and Tina struggle to reconcile their past and future selves as Angie is dealt a shocking blow on her first day of college. Meanwhile, Shane adjusts to domestic life with Tess, and Alice questions what she wants in a partner. At the bungalow, Finley returns from rehab and works to pick up the pieces of the life she left behind with Sophie, while Dani and Micah take big swings with Gigi and Maribel.
Polls / The L Word / The L Word Generation Q
by thelwordq · Published October 22, 2022 · Last modified October 29, 2022
The L Word Poll
So, here we are, close to the start of Season 3 already! We're wondering, are you on the edge of your seats yet, or more of an OG person?
Quizzes / The L Word / The L Word Generation Q
by thelwordq · Published October 22, 2022 · Last modified November 3, 2022
Who said it?
How well do you know The L Word? Take the quiz and find out now! 60 seconds per question, no cheating 😉

redpajama_set_name: RedPajamaCommonCrawl


Mobile dust extractor design is built to deliver maximum mobility used with the Bosch cordless GBH18V-26D D-handle Bulldog™. HEPA filter so users can move toward OSHA silica dust regulation compliance. Two Dust-Eyes and 4" extension available in 5/8" and 1" sizes for use with bits 5/32" to 1" diameter and up to 10" in length. Aluminum guide rail provides smooth retraction of the Dust Eye during the drilling application. Dust container provides capacity for up to 20 holes using a ½" diameter bit drilling 2" deep into concrete. Compatible with Bosch 2KG D-Handle Bulldog™ hammers – designed to fit 1" 11255VSR and 1-1/8" GBH2-28L and RH228VC corded models, as well as the 1" 18V GBH18V-26D cordless model. Includes: SDS-plus® Bulldog™ Mobile Dust Extractor, dust container, HEPA filter, auxiliary handle, 5/8 in. dust eye, 1" dust eye, and 4" extension.
The only universal tool of its kind on the market, the HAMMERVAC™ Vacuum Assisted Dust Extractor delivers a universal solution at low cost of ownership for dust extraction needs. The HAMMERVAC™ universal handle system allows quick set up and is compatible with major brands of SDS Plus rotary hammers and AC/DC hammer drills so users can drill safely into concrete and masonry without purchasing a new drill. It features a universal vacuum attachment system that is compatible with standard hose sizes of wet dry vacuums. This allows a standard wet dry vacuum to provide power and suction needed to remove dust as holes are drilled. Includes (3) side handle clamping collar assemblies, a replacement nozzle, adjustable depth stop and ruler.
SDS Max Dust Extraction Attachment provides users with a solution for the regulation on respirable crystalline silica dust (29 CFR 1926.1153). The SDS Max Dust Extraction Attachment is optimized for all drilling depths and any hole ranging from ¼" and 2-3/4" in diameter. Its removable brush rings allows for increased tool life when performing larger dry coring applications. Attach to the Milwaukee (25-0282) 8 Gallon Dust Extractor for a complete OSHA Table 1 compliant solution.
Compatible with major power tool brands of SDS Plus Rotary Hammers and AC / DC Hammer drills, the M12™ HAMMERVAC™ Universal Dust Extractor is the industry's only Universal dust extractor. Featuring a replaceable certified HEPA filter for high quality debris filtration, the user is able to replace the filter independently of the dust box to cost-effectively maintain suction efficiency. Powered by the M12™ RED LITHIUM battery pack for maximum portability. Kit includes: M12™ HAMMERVAC™ Universal Dust Extractor, (2) M12™ RED LITHIUM battery, (1) M12™ Lithium-ion Battery Charger, carrying case, HEPA filter, nozzles, and side handle clamping collar assemblies.
The industry's first OSHA® compliance solution without a vacuum, ideal for overhead drilling applications. The universal fit allows the DUST TRAP™ to work with all SDS Plus rotary hammers and SDS Plus drill bits up to an 8" length, including stop bits and other anchor installations tools. The clear sleeve allows visibility.
Dust collection shroud with flush grinding door allows dust collection for flush edge grinding. Universal vacuum hose connection locks onto the tool with a twist and click eliminating the use of tape to secure the hose to the shroud.
5"/ 6" Cutting and Tuckpointing Dust Shroud delivers tool-free shroud removal and adjustments and eliminates the need for user to tape hose to shroud. Includes dust collection and depth adjustment.
Dust Extractor Telescope with Hose for SDS Rotary Hammers filters dust and debris during high performance drilling. Dust extraction lasts two seconds after drill is switched off for an efficient clean.
When used with a dust extractor, DEWALT's Hollow Drill bit extracts dust while drilling for less dust, fast holes and fast adhesive anchor installation. The bit is also OSHA Table 1 compliant.
The DWH053K Large Hammer Dust Extraction is compatible with all DEWALT SDS MAX/Hex combo hammers and breakers and fits the D25553K, D25651K, D25831K DEWALT Spline Drive Hammers.
Table 1-compliant dust management solution for 1" SDS Plus rotary hammers. 2-second power off delay ensures dust extraction to continue after drill is switched off. Clear, durable dust box ensures users can see when dust box needs to be emptied. Built-in motor increases suction and high tool performance. Drill up to 5/8" diameter, 4" useable length, and 6" overall length bits. Fits into tight spaces on scissor lifts and between overhead pipes and ductwork.
This OSHA Table 1-compliant Dust Extractor works with the cordless DCH293 and the corded D25333 1-1/8 in. Rotary Hammers. It features an OSHA 1926.1153-compliant Dust Box Assembly. With a filter cleaning mechanism and a HEPA filter, it removes 99.97% of airborne particles 0.3 microns or greater. This Dust Extractor has a powerful fan assembly for increased suction during high-performance drilling. It allows users to drill up to 1" diameter, to depths up to 10". Install large diameter sleeve, stud/wedge, and screw anchors using our onboard dust extractor.
The DWH052 Large Hammer Dust Extraction is compatible with DEWALT Demo Hammers D25980 and D25960 and accepts DEWALT Pointed and Flat Chisels up to 1.25" wide. Fits DW Universal Hose Connector which allows for quick connection to hose & swivel capability.
Two interchangeable drilling heads for optimum dust removal. One for holes up to 1-1/2" and one for holes up to 2". Tough rubber seal allows for adhesion to most masonry surfaces. Two hole cleaning nozzles match nozzle to hole size for optimal hole cleaning. Fits DW universal hose connector which allows for quick connection to hose and swivel capability. Includes: 5/16" hole cleaning tube, 9/16" hole cleaning tube, 1-1/2" hole drilling head attachment, 2" hole drilling head attachment, dust extractor body and kit box.
Bosch SDS-plus® Dust-Collection Attachment provides excellent dust collection when drilling with Bosch hammers. This attachment fits most new Bosch SDS-plus® hammers, coupling via a unique side-handle interface. The attachment has a metal telescoping arm for precise retraction and can accommodate up to a 4-3/4-In. drilling depth, and it can be adjusted forward or back with a clamping band to accommodate a variety of bit lengths. The dust port can be hooked up to a 1-3/8-In. vacuum hose nozzle, or it can accommodate 1-1/4" or 2" nozzles when combined with an appropriate optional adapter. Includes: Dust collection attachment, thin wall core bit cap.
The HDC200 is a flexible dust collection attachment SDS-max® hammers for drilling into concrete. It is optimized for drilling diameters from 5/8 In. to 1-3/8 In. but can accommodate up to 2-1/2 In. if the brush ring is removed. The attachment features two unique air chambers: one allows the drilling bit to pass through when drilling into the work surface. The second air chamber is designed to maintain suction to the wall during the drilling application. The dust port is designed for Bosch 1-3/8 In. vacuum nozzle but can be used with either 1-1/4 In. or 2 In. vacuum nozzles when used with the appropriate adapter. The system is universal and is designed to connect to a vacuum so that it can be used with any size hammer and can accommodate the full range of drill bit diameters and drilling depth.
Universal vacuum hose adapter provides versatility for attaching different sized hoses. Connects 1-1/4 and 1-1/2 In. hoses to tools and attachments. Designed for Bosch products but also fits other brands. High quality construction provides strength and durability.


Transform your workplace's interiors with Interior Wraps!
Is your workplace in need of refreshed furniture and fittings? Perhaps you have tired doors, wear and tear on tables or want to introduce a different look and feel to worktops and counters?
Interior wraps can prove an effective and purse-friendly way of reviving a building's interior, allowing you to upgrade your office and work space quickly without causing disruption to your teams.
To replace or refurbish tired furniture or office fittings can be incredibly costly, not to mention disruptive to your organisation. This expensive capital expenditure can be better invested into other aspects of your business, but it's still important to present a professional working environment to both your own employees and visitors.
An improved and refreshed work space will lead to greater productivity and better employee morale. Interior wraps are quick to install, inexpensive – often saving over 50% of the cost of refurbishment – and have an immediate effect, injecting new life into your interiors and guaranteed to last for 10 years.
Interior wraps are a great way of giving your furnishings, fixtures and fittings a boost without incurring significant costs. Installation by our film and wrap experts is quick and mess-free, meaning that your business can carry on as normal and, if required, ARC Window Films will work around you to make sure that we're onsite at less busy times.
The options for interior wraps are endless! This versatile product with over 500 finishes to choose from can completely transform desks, tables, counters, worktops, doors and walls, creating a modern and up-to-date space that's durable, guaranteed and long-lasting.
How do interior wraps work?
This adhesive vinyl wrap is a laminate covering used to create an expensive look at a fraction of the cost. ARC Window Films can supply a wide range of colours, styles and designs to suit your corporate branding or interior design requirements, including architectural styles from authentic wood-look patterns to stone, metal and carbon fibre effects for a quick and easy refurbishment that makes a real impact.
Interior wraps are quick and non-disruptive to apply. We use a high-quality product with air-release adhesive for a bubble-free installation, and the film can be installed to most surfaces, from ceilings and furniture to lifts, doors and office walls.
Modern architectural styles suit interior wraps perfectly. The industrial look of 'raw' natural materials such as wood and stone can be recreated in any building using a simple wrap, and our wrap styles constantly keep up-to-date with modern interior design trends.
From leather, wood and natural stone, there are countless options to choose from; we even supply a glitter wrap for an extra touch of sparkle!
ARC Window Films are film application specialists. We have a wealth of experience in the supply and installation of quality window films, including interior wraps, graphics, and window films. You can be sure of a product that's of a superior standard, installed by experts who respect your workplace and understand how to apply film for a beautifully seamless finish.
Interior wraps make an excellent addition to an interior designer's portfolio and our team would be pleased to work with you to recommend, supply and install wraps that will transform spaces. If you occupy or manage a building and would like to contact us for advice and samples, please get in touch!
Contact ARC Window Films now on 0333 800 2400 to find out more about our interior wraps!
Why choose Thermal Window Film?


text:
namespace grpc_event_engine {
namespace posix_engine {

TEST(TimerManagerTest, StressTest) {
  grpc_core::ExecCtx exec_ctx;
  auto now = grpc_core::Timestamp::Now();
  auto test_deadline = now + grpc_core::Duration::Seconds(15);
  std::vector<Timer> timers;
  constexpr int kTimerCount = 500;
  timers.resize(kTimerCount);
  std::atomic_int called{0};
  std::random_device rd;
  std::mt19937 gen(rd());
  std::uniform_real_distribution<> dis_millis(100, 3000);
  auto pool = std::make_shared<grpc_event_engine::experimental::ThreadPool>();
  {
    TimerManager manager(pool);
    for (auto& timer : timers) {
      exec_ctx.InvalidateNow();
      manager.TimerInit(
          &timer, now + grpc_core::Duration::Milliseconds(dis_millis(gen)),
          experimental::SelfDeletingClosure::Create([&called]() {
            absl::SleepFor(absl::Milliseconds(50));
            ++called;
          }));
    }
    // Wait for all callbacks to have been called
    while (called.load(std::memory_order_relaxed) < kTimerCount) {
      exec_ctx.InvalidateNow();
      if (grpc_core::Timestamp::Now() > test_deadline) {
        FAIL() << "Deadline exceeded. "
               << called.load(std::memory_order_relaxed) << "/" << kTimerCount
               << " callbacks executed";
      }
      gpr_log(GPR_DEBUG, "Processed %d/%d callbacks",
              called.load(std::memory_order_relaxed), kTimerCount);
      absl::SleepFor(absl::Milliseconds(333));
    }
  }
  pool->Quiesce();
}

TEST(TimerManagerTest, ShutDownBeforeAllCallbacksAreExecuted) {
  // Should the internal timer_list complain in this scenario?
  grpc_core::ExecCtx exec_ctx;
  std::vector<Timer> timers;
  constexpr int kTimerCount = 100;
  timers.resize(kTimerCount);
  std::atomic_int called{0};
  experimental::AnyInvocableClosure closure([&called] { ++called; });
  auto pool = std::make_shared<grpc_event_engine::experimental::ThreadPool>();
  {
    TimerManager manager(pool);
    for (auto& timer : timers) {
      manager.TimerInit(&timer, grpc_core::Timestamp::InfFuture(), &closure);
    }
  }
  ASSERT_EQ(called.load(), 0);
  pool->Quiesce();
}

}  // namespace posix_engine
}  // namespace grpc_event_engine

int main(int argc, char** argv) {
  grpc::testing::TestEnvironment env(&argc, argv);
  ::testing::InitGoogleTest(&argc, argv);
  grpc_init();
  int ret = RUN_ALL_TESTS();
  grpc_shutdown();
  return ret;
}

redpajama_set_name: RedPajamaGithub


Hand-gathered in late April 2018 at 1600 meters above sea level, our Alishan oolong comes from a garden that has provided us with tea for the past seven years. It's a garden that for the past few years have won repeated accolades for the quality and character of its tea. Their harvest season spans twelve days, and during that time, tea-picking, oxidation, roasting and rolling occurs around the clock. Each step in the process is mindfully controlled to ensure that the tea is crafted to optimize its aroma, taste and finish.
This year's harvest season was marked by days of heavy rain interspersed with unseasonably warm days. The result was a significantly lower quantity of tea picked, but skilled craftsmanship turned that small amount into an exceptionally wonderful tea. This batch counts as one of the best we've tasted - intensely flavorful and aromatic, without sacrificing mouth feel or sweetness.
High elevation oolongs from Alishan usually carry notes of citrus and apples. This year's harvest has suprised us with a thick buttery character.
Properly brewed, Alishan has a balance of floral and fruit notes, with an engaging but not overbearing creaminess.
In a gaiwan or small tea pot, we prefer steeping 4.5 grams of this tea at 200 degrees for 2 minutes on the initial brew, then increasing that in increments of 30 seconds after the second brew. For lighter infusions, use cooler water and extend the steeping time.


CJ Cleaning & Maintenance strives to provide our clients with the highest quality and trouble free service available. We accomplish this by recognizing that every client has different needs. We listen to your needs and then custom tailor our professional personnel, equipment and resources to meet them. Our low turnover in staff is one of the many reasons we have provided excellent service since 1998.
As the founder of this company I make myself available to every client at any time for whatever the reason.


When you're ill, and you reach the threshold of what you consider 'enough pain to warrant treatment,' you can do a number of things: you can continue to live with the pain, you can try at-home remedies, you can seek out holistic forms of treatment that exist outside the medical realm, or you can go to the doctor.
Pain is a matter of perception. Most adults know when we're in enough pain to seek treatment. Adults are seen as having certain rights to their bodies, to experience the world in their own way, and to deal with the scrapes and bruises life has dealt them as they find appropriate, and to make decisions regarding their bodies. This is a bit of a fantasy on the part of American society, however; it is well known and accounted for that women have not always been seen as full citizens in the United States, within and outside of the healthcare sector.
Women's bodies have not been accorded autonomy in the way that men's bodies have been accorded autonomy, in both the public and private sector. Women's bodies, queer bodies, (dis)abled bodies, African American bodies, and Native American bodies have been raped, molested, denied autonomy, controlled, exploited, and treated as objects for white male patriarchal profit and gain across time. The painful reality is that these heinous and objectifying American "traditions" on which our county, and its medical industry, were built continue to plague us as a society, preventing us from radical and collective healing.
But daily bumps and aches, cancers and sciatic pains, plague us all, and so we must try to grapple with what it means to live in a world in which illness is as American, as human, and as common, as apple pie, as petty theft, as breath.
Whether it's your ankle that hurts, your knee that's sore, your tooth that aches, your heart that hurts, or something else: you decide when it is time to seek the advice of a professional, and sometimes (if your homeland offers universalized health care or if you are a member of an elite) you can choose the professional who will assess your condition. You might be prodded by a nagging neighbor or urged to seek help from friends and family, if you are stubborn; but you, ultimately, have the right to decide whether or not, and when, you need treatment. Doctors don't police the street looking for potential patients, for red elbows or pink eyes or hangnails, in need of treatment.
In general, it is not common for members of American society in this day and age to fear physicians because when it comes to generalized medical care, patients are seen as having the right: to seek, to not seek, to pursue, or to deny treatment. Most Americans do not have to worry that when they go to see a physician, some terrible tragedy will unfold. They don't have to worry that they will go to see a physician and not be allowed out of the office.
Most Americans don't have to worry that their doctor is going to harm them: to stab them in the heart when they come in for heart failure or to kick them in the knee when they come in for a bad knee or to make them more sick than when they came in seeking help. Most Americans don't have to worry about how others are going to treat them because they had to go to the hospital for diverticulitis or because the flu knocked them out for two weeks. Most Americans don't have to worry that their pancreatitis is going to cause the police to drive down their street, checking up on their pancreas.
Most Americans don't have to worry that their doctor might harness them to a bed if they go in seeking treatment for their ulcers. If most Americans had to fear that their illness would result in their loss of rights, in the ripping away of their autonomy; most Americans would NOT seek treatment– they would not go to the doctor, they would try to hide whatever aches and pains they might experience. Or they might revolt because they would know that such imperialist treatment is wrong.
No one can force an adult to go through chemotherapy if that adult chooses not to do so. No one can force an adult to have her broken ankle wrapped if she prefers to let it heal at home. These examples involve physical ailments– ones recognized and recognizable.
When you are unwell, and you perceive yourself as being ill, you know one thing: you know you have, or should have, the right to choose.
But what happens when you are well.
What happens when you're well but others believe you are ill.
What happens when someone is well, when someone feels fine, and is going about their business being fine and treating others well.
What happens when an individual is well and meets up with a group that has the power to call this wellness into question.
The above dialogue is fictional and is intended to raise issues related to patient autonomy.
There is a difference between someone going to the doctor because they feel sick– and a group of people deciding that someone else is sick and needs care. Who gets to say who is sick and injured? Who gets to decide if someone is ill, or well, and what treatment, if any, is best? The patient? The doctor? Schmucks on the street?
Patient rights matter because human rights matter. Because patients are human beings.
Here, Woolf addresses the absurdity of not thinking of illness as an entity as central and fascinating to the human experience as love. She also, through painting illness as a path into art, reverses our expectations about the nature of illness, and her prose suggests that in illness there is a kind of wellness– a wellness of spirit that brings the one who is ill into a state of perception about the human experience that is deeper and more beautiful than can be experienced in wellness. Woolf's profound sentiment is that one kind of illness can give birth to another kind of wellness, a wellness derived from illness, a wellness through the consciousness altered into observation by illness. She collapses the binary of wellness/illness by making one compact within the other, able to coexist with the other, able to be born of the other. "On being ill," then, is also on being well, well through all that the lens of being "ill" has taught us to see: all in life that one who has not been well-and-ill in this way is unable to perceive.
Woolf wrote this as someone who struggled with illness, with being different, at a time when women were considered ill for defying notions of traditional womanhood or for being disobedient to their husbands. Woolf wrote this at a time when patient rights were non-existent– when the will of the husband over the wife, the doctor over the patient, superseded anything she might have done, said, or written.
She created wellness from illness.
Her words instruct us how to be well in a world that might be ill, in a world that might make us ill.


The Advanced Band and Advanced Orchestra students participated in an SCSBOA (Southern California School Band and Orchestra) festival at Montebello High School.
Students prepared selections of music and were adjudicated by professional band and orchestra specialists against a national music education standards based rubric. The orchestra received a unanimous excellent rating. The band received a combination good/excellent rating.
Congratulations Woodland Hills Academy music students!
Students from WHA recorded original movie score selections from Disney's Lion King, Tangled and Atlantis in a 90 minute workshop with a professional Disney Conductor. This activity provided our students with real world experience of what it takes to be a studio musician.


At Land Rover Troy, we firmly believe your Land Rover is not just a vehicle; it's something to be treasured. As such, if you want to enjoy the unbridled luxury and performance potential of your Land Rover vehicle for years to come, it's essential to keep up with Land Rover recommended maintenance and care. Fortunately, with years of experience serving drivers all over Troy, MI and nearby Birmingham, Bloomfield and Royal Oak, MI, our Land Rover Troy service center is the first and only place you should turn to for all your Land Rover maintenance and repair needs.
Unlike many other service centers here in Michigan, we here at Land Rover Troy strive to provide the white glove standard of service that drivers of discerning tastes have come to expect from the Land Rover Brand. With our factory-certified Land Rover technicians on staff and the latest in tools and genuine Land Rover parts at our disposal, our Land Rover service center is well-equipped to handle your every maintenance need. Best of all, we strive to do so in a comprehensive and timely manner, helping you get back out on the road as quickly as possible.
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text:
Raazi: Alia Bhatt On Patriotism And The Time She Took 11 Takes On Set
HomeEntertainmentRaazi: Alia Bhatt On Patriotism And The Time She Took 11 Takes On Set
This Article is From May 07, 2018
In Raazi, Alia Bhatt plays the role of an Indian spy who marries a Pakistani man
EntertainmentRohit KhilnaniUpdated: May 07, 2018 4:22 pm IST
Alia Bhatt in Raazi (Image courtesy: YouTube)
"I feel very grateful and extremely happy," she said
Raazi is directed by Meghna Gulzar
Raazi releases this Friday
Mumbai: In Meghna Gulzar's Raazi, actress Alia Bhatt plays the role of an Indian spy who marries a Pakistani man. It's an intriguing story based on Harinder Sikka's novel Calling Sehmat. In this interview with NDTV.com, Alia praises unsung heroes like Sehmat who risk their lives and fight for the country. She says her biggest takeaway from the film was an appreciation of the selflessness of Sehmat and others like her who put themselves in harm's way for their country. These are the true patriots, says Alia Bhatt. And, by the way, just in case you are among those who think Alia can do no wrong - prepare to be surprised.
Q: Explain to us how is it to work with Meghna Gulzar, what is she like on the set?
Alia Bhatt: "Overall she is in control of everything - she knows exactly what she wants. But she lets the crew do her thing and work at their comfort and pace. She is not one of those directors who is talking on the microphone and screaming at people. She likes to let an actor come and explore the scene. Because we have done so much prep work beforehand and had many conversations, we didn't have to discover many things on the set. Her tones were all discussed and ironed out before I reached the set. That's comforting for an actor - you don't feel alone. Whenever she could she would always control the atmosphere because this is an emotional film, you need a particular kind of an environment when you are shooting a film like Raazi."
Q: Meghna said that without you, she would not have made Raazi. Just six years into your acting career you have filmmakers writing roles for you. What's that like?
Alia Bhatt: "I feel very grateful and extremely happy. If this film had gone to someone else, then God knows how my journey would have been as an actor. My ultimate goal is to keep my director happy. The only person who is allowed to be selfish on a film set is the director. We all move on, and do other work and other films while she is still working on this one. I have only worked for 48 days, I am doing two other films but the director has just this one film. I feel responsible towards my director. After I watched Talvar, I wanted to work with her. That idea that she thought of me, I feel grateful and blessed. I hunt for good directors and writers."
Q: So now who you are looking at next? Anyone, in particular, you want to work with.
Alia Bhatt: "Juhi Chaturvedi (writer of Vicky Donor, Piku, October). I love her work, and I am on the hunt (laughs). Juhi, I hope you are reading this - I am looking out for you! I want her to write something for me."
Q: How long does a film stay with you after it's out. When do you move on?
Alia Bhatt: "Oh, it's awful! This experience of letting your film go is tough. Like right now, this phase is such a high, we are together we are being emotional and promoting the film. It's like you are on the top of a mountain and you don't know what to do after it's out. It's like getting over a very serious relationship. I don't snap out of it but I snap into something else, and that's the best way to move on."
Q: How does a film like Raazi affect you?
Alia Bhatt: "A film like this does affect you. Technically, we are living with that story for 48 days, shooting nine scenes a day that's 14 hours a day. I don't have time even to read a book - all you are doing is sleeping and acting. That character becomes a very big reality. Post-shooting a long schedule is when you settle down suddenly the adrenaline is out of your body and you are hit. My father says its like you are treated like a war victim; suddenly you are done with it."
Q: What's your biggest takeaway from Raazi?
Alia Bhatt: "The story of this character! It's such a selfless act. There are not that many selfless deeds that exist in today's world. Some acts that may seem selfless will have a hint of selfishness in it, maybe in a good way. One big takeaway is that I really have respect for those who are day in and day out fighting for the country. I always had respect for them, I have done a trail of the BSF borders, and I have spent time with them. But I never sat back and understood that they have put their lives out there. And there are also so many unsung heroes who have given up their lives, and we have no clue where they are. Just by putting themselves out there in the mouth of danger for us they have done so much for us. We should take a moment to think that do we really understand the true meaning of patriotism. Do we really understand the meaning of it?"
Q: Since Raazi is based on the book Calling Sehmat, why didn't you read the book?
Alia Bhatt: "The book is not available, but the author gave me the book. So I was thought at least I should go through the parts that are in the film. There was no need to get into anything that's not in the movie. My script was my book. The book is quite extensive and goes into other characters' journey."
Q: You have done a variety of roles in your six-year-long career and critics and fans have always praised your work. There are people feel you can do no wrong. What do you want to say to them?
Alia Bhatt: "That's very sweet. Expectations are always difficult to keep up to. I do wrong - I took eleven takes for one scene on the set of Kalank the other day (Laughs). For me, that's wrong because I don't usually take more than three takes. I fumble and stumble but thank you for all your support and hope I don't disappoint you. Hope you watch Raazi, it's very special to my heart."
Watch: Alia Bhatt on Raazi
Raazi, co-starring Vicky Kaushal, Rajit Kapur and Alia's mother Soni Razdan, releases this week.
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I do not have the answer to your question but I do have a design suggestion. SIMPLIFY your content and your colors. Your page is a bunch of small areas all screaming for my attention and I do not know where to look first.
Your visitors are looking for specific information when she or he visits your site. Maybe have a simple list of topics and either link each topic to a simple page, or a pop-up layer with a simple explanation.
I love the idea of a mobile notary. I seem to remember when we had our design business in San Francisco years ago a notary who would come to the office. It was so much more convenient.
You have attached so code that keeps the browser idle for almost 1.5 seconds; this code is not a Xara addition AFAICS. Focus on a simpler page design with fewer font changes and split the page into several.


Thank you so much to David and Dilys Astin who popped in with their cheque after organising the Sunshine & Smiles Benefit Concert. They raised over £3,000 on 2nd February!!
A huge thank you to the Headingley Voices, Sound Company, Free Range A Capella, and Harissa and Roger Harington for making the evening so magical, and thank you for inviting us to bring along our pop up Café 21 to serve our delicious cake, teas & coffees to everyone at the interval.
We can't thank you enough for choosing to raise funds for our charity, and thank you to all the people who came along to listen!


text:
Probing the Superfluid–to–Mott Insulator Transition at the Single-Atom Level
W. S. Bakr1,
A. Peng1,
M. E. Tai1,
R. Ma1,
J. Simon1,
J. I. Gillen1,
S. Fölling1,2,
L. Pollet1,
M. Greiner1,*
1Department of Physics, Harvard University, Cambridge, MA 02138, USA.
2Institut für Physik, Ludwig-Maximilians-Universität, 80799 München, Germany.
↵*To whom correspondence should be addressed. E-mail: greiner{at}physics.harvard.edu
Science 30 Jul 2010:
W. S. Bakr
A. Peng
M. E. Tai
R. Ma
J. Simon
J. I. Gillen
S. Fölling
L. Pollet
M. Greiner
For correspondence: greiner@physics.harvard.edu
Quantum gases in optical lattices offer an opportunity to experimentally realize and explore condensed matter models in a clean, tunable system. We used single atom–single lattice site imaging to investigate the Bose-Hubbard model on a microscopic level. Our technique enables space- and time-resolved characterization of the number statistics across the superfluid–Mott insulator quantum phase transition. Site-resolved probing of fluctuations provides us with a sensitive local thermometer, allows us to identify microscopic heterostructures of low-entropy Mott domains, and enables us to measure local quantum dynamics, revealing surprisingly fast transition time scales. Our results may serve as a benchmark for theoretical studies of quantum dynamics, and may guide the engineering of low-entropy phases in a lattice.
You are going to email the following Probing the Superfluid–to–Mott Insulator Transition at the Single-Atom Level
By W. S. Bakr, A. Peng, M. E. Tai, R. Ma, J. Simon, J. I. Gillen, S. Fölling, L. Pollet, M. Greiner
Science 30 Jul 2010 : 547-550
Imaging of atoms that were optically trapped in lattice sites reveals local dynamics of a quantum phase transition.


- Always operate under adult supervision. The safety on the children depends on you. Your personal supervision is absolutely required at all times.
- Only compatible age groups and sizes shall play on the moonwalk at the same time.
- Extra caution and supervision are required for children ages three (3) and under.
- Never allow older kids to bounce with children ages (3) and under unless they are supervised.
- Keep toddlers from putting netting in mouth.
injury from falls, bumps or bouncing) are not permitted in or on the unit at any time.
- Remove shoes, glasses and jewelry.
- All personnel must remove shoes, glasses and jewelry before playing in the Moonwalk.
- No flips, wrestling, piling or extreme horseplay.
- As with flipping, improper use of the inflatable includes wrestling and riders piling on themselves.
Such activity may result in neck and back injuries to riders. these activities are not allowed.
- Absolutely no- Silly String.
(confetti, gum, food, drinks, sprays, or other sticky substances are allowed in or around Moonwalk.
- Should "Silly String" come in contact with the moonwalk, it would cause irreparable damage.
- No Sharp Objects allowed inside or around the moonwalk.
- Do not Bounce against the sides or near the doorway of the unit- serious injuries may result.
- Do not jump on the inflatable step area of the Moonwalk.
- Do not hanging from the netting on the sides.
- Stay off netting at all times.
- Do not allow climbing on the unit.
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- Do not allow climbing on the unit itself or the netting by persons either inside or outside of the moonwalk.
- A repair fee will be imposed if the sides/ roof is damaged from misuse.
- Do not put water inside the inflatable bouncers.
- Jumping inside the bouncer can be dangerous if the surface is slippery.
- REMOVE THE CHILDREN IMMEDIATELY.
- If the motor has stopped, make sure that it has been unplugged.. if the motor is still running, check the the air-take screen on the sidemotor.
- Make sure the breaker for the outlet has not tripped. If the problem persists, try another power outlet.
- Also check both blower tubes on the back of the moonwalk to make sure that they are tightly tied off.
- Never allow riders to jump in a partially inflated unit.
- Keep children away from the blower.
- Do not deflate the unit (unless rain is imminent) So that it may be inspected and cleaned prior to departure from the premises.
- In case of rain and thunderstorms.
- Remove all persons from the Moonwalk and turn off the motor.
- When the thunderstorms and rain stop, first dry inside of the moonwalk with a soft clean towel before, in order to prevent slips.
- Do not use the Moonwalk if the wind exceed of 20 mph. (The unit can flip over) and Severe cold weather (below 40 degrees).
- Children should immediately exit of the moonwalk.
- The blower should there after be switched off and the unit allowed to deflate.
- Do not remove the Moonwalk from the area where it was installed.
- If the inflatable unit moves, pull it by one of its corners back to its original location of installation.
- Keep the inflatable unit away from swimming pools at all times.
- No alteration in or attachments to the moonwalk area allowed period.


text:
Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness
Mandy Johnstone, Alan Maclean, Lien Heyrman, An-Sofie Lenaerts, Annelie Nordin, Lars-Göran Nilsson, Peter De Rijk, Dirk Goossens, Rolf Adolfsson, David M St Clair, Jeremy Hall, Stephen M Lawrie, Andrew M McIntosh, Jurgen Del-Favero, Douglas H R Blackwood, Benjamin S Pickard
Applied Medicine
Robust statistical, genetic and functional evidence supports a role for DISC1 in the aetiology of major mental illness. Furthermore, many of its protein-binding partners show evidence for involvement in the pathophysiology of a range of neurodevelopmental and psychiatric disorders. Copy number variants (CNVs) are suspected to play an important causal role in these disorders. In this study, CNV analysis of DISC1 and its binding partners PAFAH1B1, NDE1, NDEL1, FEZ1, MAP1A, CIT and PDE4B in Scottish and Northern Swedish population-based samples was carried out using multiplex amplicon quantification. Here, we report the finding of rare CNVs in DISC1, NDE1 (together with adjacent genes within the 16p13.11 duplication), NDEL1 (including the overlapping MYH10 gene) and CIT. Our findings provide further evidence for involvement of DISC1 and its interaction partners in neuropsychiatric disorders and also for a role of structural variants in the aetiology of these devastating diseases.
Journal of Neuropsychiatry and Clinical Neurosciences
Overlapping Genes
Protein Binding
copy number variants
NDE1
NDEL1
affective disorder
Johnstone, M., Maclean, A., Heyrman, L., Lenaerts, A-S., Nordin, A., Nilsson, L-G., ... Pickard, B. S. (2015). Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness. Journal of Neuropsychiatry and Clinical Neurosciences, 1(3), 175-190. https://doi.org/10.1159/000438788
Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness. / Johnstone, Mandy; Maclean, Alan; Heyrman, Lien; Lenaerts, An-Sofie; Nordin, Annelie; Nilsson, Lars-Göran; De Rijk, Peter; Goossens, Dirk; Adolfsson, Rolf; St Clair, David M; Hall, Jeremy; Lawrie, Stephen M; McIntosh, Andrew M; Del-Favero, Jurgen; Blackwood, Douglas H R; Pickard, Benjamin S.
In: Journal of Neuropsychiatry and Clinical Neurosciences, Vol. 1, No. 3, 10.2015, p. 175-190.
Johnstone, M, Maclean, A, Heyrman, L, Lenaerts, A-S, Nordin, A, Nilsson, L-G, De Rijk, P, Goossens, D, Adolfsson, R, St Clair, DM, Hall, J, Lawrie, SM, McIntosh, AM, Del-Favero, J, Blackwood, DHR & Pickard, BS 2015, 'Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness', Journal of Neuropsychiatry and Clinical Neurosciences, vol. 1, no. 3, pp. 175-190. https://doi.org/10.1159/000438788
Johnstone M, Maclean A, Heyrman L, Lenaerts A-S, Nordin A, Nilsson L-G et al. Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness. Journal of Neuropsychiatry and Clinical Neurosciences. 2015 Oct;1(3):175-190. https://doi.org/10.1159/000438788
Johnstone, Mandy ; Maclean, Alan ; Heyrman, Lien ; Lenaerts, An-Sofie ; Nordin, Annelie ; Nilsson, Lars-Göran ; De Rijk, Peter ; Goossens, Dirk ; Adolfsson, Rolf ; St Clair, David M ; Hall, Jeremy ; Lawrie, Stephen M ; McIntosh, Andrew M ; Del-Favero, Jurgen ; Blackwood, Douglas H R ; Pickard, Benjamin S. / Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness. In: Journal of Neuropsychiatry and Clinical Neurosciences. 2015 ; Vol. 1, No. 3. pp. 175-190.
@article{4fd9aea464f94e63b15a578497ac3bf9,
title = "Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness",
abstract = "Robust statistical, genetic and functional evidence supports a role for DISC1 in the aetiology of major mental illness. Furthermore, many of its protein-binding partners show evidence for involvement in the pathophysiology of a range of neurodevelopmental and psychiatric disorders. Copy number variants (CNVs) are suspected to play an important causal role in these disorders. In this study, CNV analysis of DISC1 and its binding partners PAFAH1B1, NDE1, NDEL1, FEZ1, MAP1A, CIT and PDE4B in Scottish and Northern Swedish population-based samples was carried out using multiplex amplicon quantification. Here, we report the finding of rare CNVs in DISC1, NDE1 (together with adjacent genes within the 16p13.11 duplication), NDEL1 (including the overlapping MYH10 gene) and CIT. Our findings provide further evidence for involvement of DISC1 and its interaction partners in neuropsychiatric disorders and also for a role of structural variants in the aetiology of these devastating diseases.",
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author = "Mandy Johnstone and Alan Maclean and Lien Heyrman and An-Sofie Lenaerts and Annelie Nordin and Lars-G{\"o}ran Nilsson and {De Rijk}, Peter and Dirk Goossens and Rolf Adolfsson and {St Clair}, {David M} and Jeremy Hall and Lawrie, {Stephen M} and McIntosh, {Andrew M} and Jurgen Del-Favero and Blackwood, {Douglas H R} and Pickard, {Benjamin S}",
note = "Acknowledgements We would like to thank all of the patients, relatives and control individuals who participated in the study. We are indebted to the late Prof. Walter Muir, Chair of Developmental Psychiatry and Honorary Consultant in Learning Disability Psychiatry, University of Edinburgh, who initiated these studies and whose work was dedicated to the welfare of the patients who generously participated. We are also grateful to Mrs. Pat Malloy for her assistance with DNA collection and MAQ assays screening of the Scottish samples. The Scottish sample collection was supported by a grant from the Chief Scientist Office (CSO), part of the Scottish Government Health and Social Care Directorates. This research was funded by grants from the CSO to B.S.P. (grant CZB/4/610), The Academy of Medical Sciences/Wellcome Trust to M.J. (grant R41455) and The RS Macdonald Charitable Trust (grant D21419 together with J.H.), the Swedish Research Council (grants 2003-5158 and 2006-4472), the Medical Faculty, Ume{\aa} University, and the County Councils of V{\"a}sterbotten and Norrbotten, Sweden, as well as by grants from the Fund for Scientific Research Flanders (FWO-F), the Industrial Research Fund (IWT) and the Special Research Fund of the University of Antwerp, Belgium. M.J. is funded by a Wellcome Trust Clinical Research Fellowship for MB PhD graduates (R42811). We acknowledge the contribution of the personnel of the VIB Genetic Service Facility (http://www.vibgeneticservicefacility.be/) for the genetic analysis of the Swedish samples. Research nurses Gunnel Johansson, Lotta Kronberg, Tage Johansson and Lisbeth Bertilsson are thankfully acknowledged for their help and expertise. The Betula Study was funded by the Swedish Research Council (grants 345-2003-3883 and 315-2004-6977). We also acknowledge the contribution by the staff in the Betula project",
journal = "Journal of Neuropsychiatry and Clinical Neurosciences",
publisher = "American Psychiatric Publishing Inc.",
T1 - Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness
AU - Johnstone, Mandy
AU - Maclean, Alan
AU - Heyrman, Lien
AU - Lenaerts, An-Sofie
AU - Nordin, Annelie
AU - Nilsson, Lars-Göran
AU - De Rijk, Peter
AU - Goossens, Dirk
AU - Adolfsson, Rolf
AU - St Clair, David M
AU - Hall, Jeremy
AU - Lawrie, Stephen M
AU - McIntosh, Andrew M
AU - Del-Favero, Jurgen
AU - Blackwood, Douglas H R
AU - Pickard, Benjamin S
N1 - Acknowledgements We would like to thank all of the patients, relatives and control individuals who participated in the study. We are indebted to the late Prof. Walter Muir, Chair of Developmental Psychiatry and Honorary Consultant in Learning Disability Psychiatry, University of Edinburgh, who initiated these studies and whose work was dedicated to the welfare of the patients who generously participated. We are also grateful to Mrs. Pat Malloy for her assistance with DNA collection and MAQ assays screening of the Scottish samples. The Scottish sample collection was supported by a grant from the Chief Scientist Office (CSO), part of the Scottish Government Health and Social Care Directorates. This research was funded by grants from the CSO to B.S.P. (grant CZB/4/610), The Academy of Medical Sciences/Wellcome Trust to M.J. (grant R41455) and The RS Macdonald Charitable Trust (grant D21419 together with J.H.), the Swedish Research Council (grants 2003-5158 and 2006-4472), the Medical Faculty, Umeå University, and the County Councils of Västerbotten and Norrbotten, Sweden, as well as by grants from the Fund for Scientific Research Flanders (FWO-F), the Industrial Research Fund (IWT) and the Special Research Fund of the University of Antwerp, Belgium. M.J. is funded by a Wellcome Trust Clinical Research Fellowship for MB PhD graduates (R42811). We acknowledge the contribution of the personnel of the VIB Genetic Service Facility (http://www.vibgeneticservicefacility.be/) for the genetic analysis of the Swedish samples. Research nurses Gunnel Johansson, Lotta Kronberg, Tage Johansson and Lisbeth Bertilsson are thankfully acknowledged for their help and expertise. The Betula Study was funded by the Swedish Research Council (grants 345-2003-3883 and 315-2004-6977). We also acknowledge the contribution by the staff in the Betula project
N2 - Robust statistical, genetic and functional evidence supports a role for DISC1 in the aetiology of major mental illness. Furthermore, many of its protein-binding partners show evidence for involvement in the pathophysiology of a range of neurodevelopmental and psychiatric disorders. Copy number variants (CNVs) are suspected to play an important causal role in these disorders. In this study, CNV analysis of DISC1 and its binding partners PAFAH1B1, NDE1, NDEL1, FEZ1, MAP1A, CIT and PDE4B in Scottish and Northern Swedish population-based samples was carried out using multiplex amplicon quantification. Here, we report the finding of rare CNVs in DISC1, NDE1 (together with adjacent genes within the 16p13.11 duplication), NDEL1 (including the overlapping MYH10 gene) and CIT. Our findings provide further evidence for involvement of DISC1 and its interaction partners in neuropsychiatric disorders and also for a role of structural variants in the aetiology of these devastating diseases.
AB - Robust statistical, genetic and functional evidence supports a role for DISC1 in the aetiology of major mental illness. Furthermore, many of its protein-binding partners show evidence for involvement in the pathophysiology of a range of neurodevelopmental and psychiatric disorders. Copy number variants (CNVs) are suspected to play an important causal role in these disorders. In this study, CNV analysis of DISC1 and its binding partners PAFAH1B1, NDE1, NDEL1, FEZ1, MAP1A, CIT and PDE4B in Scottish and Northern Swedish population-based samples was carried out using multiplex amplicon quantification. Here, we report the finding of rare CNVs in DISC1, NDE1 (together with adjacent genes within the 16p13.11 duplication), NDEL1 (including the overlapping MYH10 gene) and CIT. Our findings provide further evidence for involvement of DISC1 and its interaction partners in neuropsychiatric disorders and also for a role of structural variants in the aetiology of these devastating diseases.
KW - copy number variants
KW - DISC1
KW - NDE1
KW - NDEL1
KW - Schizophrenia
KW - affective disorder
KW - intellectual disability
JO - Journal of Neuropsychiatry and Clinical Neurosciences
JF - Journal of Neuropsychiatry and Clinical Neurosciences
10.1159/000438788Licence: CC BY
http://creativecommons.org/licenses/by/4.0/ Open Access License / Drug Dosage / Disclaimer - http://www.karger.com/Article/FullText/438788
Final published version, 2.11 MBLicence: CC BY


text:
Every Changemaker Should Know These 3 Strategies (But Most Don't)
tags: Change, Leadership, Strategy, Transformation
All too often, we see change as a communication exercise. We think that if people really understood our idea, they would embrace it. In this view, bringing about change is really just a matter of messaging. Find the right slogan and deliver it in the right way, and you will ignite the passions required to drive transformation.
Nothing can be further from the truth. If a change is important and has real potential for impact, there will always be some people who won't like it and they will work to undermine it in ways that are dishonest, underhanded, and deceptive. Change rarely fails because people don't understand it. Most often it is actively sabotaged.
A more elegant slogan won't save you. What you need is a sound strategy to overcome resistance to change. Fortunately, we know from social and political movements that radical, transformational change is possible and, as I explained in Cascades, their principles can be highly effective in organizations. Here are three strategies that you should know.
1. Start With A Majority
Change starts with a belief. If people believe that a change is good, they will be likely to adopt it. If they believe it's bad, it's going to be tough to convince them otherwise especially, as is often the case, their beliefs are rooted in their identity and sense of self. In fact, research has shown when we are presented with facts contrary to our beliefs, we tend to question the evidence rather than our own preconceived notions.
This raises an important question: How do we come by our beliefs? As it turns out, the best indicator of not only our beliefs, but our actions, habits and even some aspects of our health, is the people around us and studies suggest that the effect extends out to even third degree relationships. So not only our friends, but the friends of our friend's friends influence us.
The truth is that majorities don't just rule, they also influence. That's why when we seek to bring about change, it's important to start with a majority. The secret is that you get to choose where you start. It might be a small, local majority of, say, three people in a room of five. As long as supporters outnumber detractors, change can move forward.
You can always expand a majority out, but as soon as you are in the minority, you will feel immediate pushback. When that happens, you can lose momentum and send the entire initiative off the rails. In many cases, you will never get the momentum back and your hopes for change will end before they really start.
There's an unfortunate aspect of human nature that drives us to want to convince skeptics. Resist it and focus on empowering your supporters.
2. Prepare For A Trigger
It's easy to confuse a moment with a movement. A movement links together small, but often disparate, groups in the context of shared purpose and shared values. A moment occurs when an event triggers a temporary decrease in resistance and opens up a window of opportunity. Movements require preparation. Moments often emerge on their own.
What's crucial for changemakers to grasp is that a trigger eventually emerges that creates a moment. It's rare that we can predict exactly when it's going to happen, but it's not too hard to see that one will come eventually and prepare for it. Political revolutions have leveraged this for decades, focusing on particular stress points in which a trigger is likely to emerge.
For example, the color revolutions in Eastern Europe targeted elections that they knew were likely to be falsified. After Martin Luther King Jr.'s failed Albany campaign, he moved on to Birmingham, because he knew that Bull Connor, the Commissioner of Public Safety, was a hothead and likely to employ the type of brutal tactics that would trigger a moment.
In much the same way, the Covid pandemic triggered digital transformation in many organizations. Economic downturns trigger efficiency measures. When a competitor comes out with a hit product, it tends to trigger enthusiasm for innovation. We don't know when these things are going to happen, but we know that they are likely to happen eventually.
One reason why so many change efforts have failed in recent years is that the movements were built in response to a moment. Once the moment comes, it's too late. You build your movement to prepare for a trigger, so that once it comes you can make the most of it.
3. Leverage Your Opposition
Change thrives on passion. The status quo always has inertia on its side and never yields its power gracefully. That's why so many would-be changemakers start out by attacking their opposition, seeking to meet them head on, expose their misconceptions and show the value of doing things differently.
This is almost always a mistake. Directly engaging with staunch opposition is unlikely to achieve anything other than exhausting and frustrating you. However, while you shouldn't directly engage your fiercest critics, you obviously can't act like they don't exist. On the contrary, you need to learn to love your haters.
In fact by listening to people who hate your idea you can identify early flaws, which gives you the opportunity to fix them before they can be used against you in any serious way. They can also help you to identify shared values. For example, the LGBTQ movement prevailed by emphasizing their commitment to stable marriages and happy families, exactly the ideas that were used against them for decades.
Perhaps most importantly, you can leverage your opposition to your advantage. If left to their own devices, they will often overreach and send people your way. Bull Connor's brutality, which he was all too eager to display for the TV cameras, furthered the cause of civil rights. In the color revolutions, the activist group Otpor found a way to even use arrests to weaken the regime and empower the revolution..
The truth is that to bring about real change you need to attract, rather than overpower. Being seen fighting the opposition may fire up your most active supporters, but it won't bring anyone to your side. However, if the enemies of change see you gaining traction, invariably they will lash out, overreach and send people your way.
Applying Strength To Weakness
In the final analysis, the reason that most would-be revolutionaries fail is that they assume the righteousness of their cause will save them. It will not. Injustice, inequity and ineffectiveness can thrive for decades and even centuries, far surpassing a human lifespan. If you think that your idea will prevail simply because you believe in it you will be sorely disappointed.
Tough, important battles can only be won with good strategy and tactics, which is why successful change agents learn how to adopt the principle of Schwerpunkt. The idea is that instead of trying to defeat your enemy with overwhelming force generally, you want to deliver overwhelming force and win a decisive victory at a particular point of attack.
Yet Schwerpunkt is a dynamic, not a static concept. You have to constantly innovate your approach as your opposition adapts to whatever success you may achieve. For example, the civil rights movement had its first successes with boycotts, but moved on to sit-ins, "Freedom Rides," community actions and eventually, mass marches.
Starting with a majority, preparing for a trigger and leveraging your opposition are only three ways you can apply strength to weakness. The key to success isn't any particular tactic, leader or slogan but strategic flexibility. Unfortunately, that's exactly what most change efforts lack. All too often they get caught up in a strategy and double down, because it feels good to believe in something, even if it's failure.
Change, like many things, largely boils down to strategy and execution. It's not a simple matter of belief or passion. You need to learn how to operate effectively, by studying those who succeeded and those who failed, building on your successes, dusting yourself off after the inevitable setbacks, correcting mistakes and returning to fight with renewed vigor.
The 5 Immutable Laws Of Change
To Achieve Real Change, You Must First Anticipate And Overcome Resistance
There Will Always Be People Who Want To Kill Change. Here's How To Outsmart Them
The "Trigger" Strategy For Driving Radical, Transformational Change
How To Overcome Resistance To Change


Codeless game design, publishing, and distribution platform that can be used by developers and educators in Computer Science teaching.
Pros: As far as I know Game Salad was first of its kind to bring drag and drop type game development. It was a really cool feature when i started using it.
Cons: I wish there had been more tutorials online. However , I used it 2-3 years ago for a hobby project so things may have changed a lot by now.
Pros: This engine can make learning how to program games professionally a little bit easier.
Cons: The engine has limited functionality if you plan on creating anything complex.
I dabbled with Gamesalad after I decided I wanted to get into game development.
Pros: One thing is that it is mainly a drag and drop interface. You have the ability to create levels by simply putting the "stage" into your order, much like Mario Level Creator for the Nintendo game systems.
Cons: For one, unless you want to release a game that looks identical to thousands of others, you must create your own assets. Secondly, as other developers have noted, a lot of features that are must have to create a successful game are just plain out missing. Also a big learning curve, so tough for the amateur, although drag and drop interface.
Overall: As stated in my review, I played around with it awhile, but decided on using other software. However, if you have a decent graphic designer or are good at graphic design yourself, this may be for you.
Pros: So far its the easiest Software to start developing games, very self explanatory and many tutorials online. its a great way to start seeing the tip of the iceberg, the features are as easy as a few clicks, for gravity changes or any other key roll of your game.
Cons: The over all interaction to insert in the Store is a bit more tricky, but worth it.
Overall: It was my first approach many years ago, i still love it.
Pros: Quite simple to get a game started and developed the way you'd like using the drag and drop function.
Design a game the way you like it.
Pros: An easy way to create own game that you like it, for new gaming developers GameSalad is a good learner.
Pros: Nice interface HD quality. EASY with drag and drop capabilities. Working in education, makes it an easy teaching and learning program for starters.
Cons: Doesn't seem for the adult educational group....but ok for the younger grades. Would be nice to have a Free version.
Pros: GameSalad is a great beginner application to help you create your game and teach you the basics. It's very easy to use too!
Cons: The biggest con might not be that much of a con for everyone, mainly if you're looking for more freedom in what you build then you might be better off with the bigger ones, but for what it is, it works as intended.
Slightly confusing, but was easy to figure after a few tutorials.
Pros: First off, its free to use and download. It uses a simple drag-and-drop interface, making it more open to the public.
Cons: It could more powerful. They could provide more tutorial or a "first run" guide to familiarize newcomers faster.
Overall: I was able to create a short game with it. I had fun developing it and having my friends play/demo it.
Pros: Very easy to get a game started and developed the way you'd like using the drag and drop interface, also available on OSX and Windows.
Cons: Needs more customization. Not a lot of support between older Mac devices and new devices with differentiating version numbers.
Cons: Not enough features, so many more applications offer better features e.g. shaders simple coding level design this has none of that and it is a problem.
Overall: None really was nice to look at but not many benefits at all find it lacking in a lot of departments.
Pros: Dragg and drop interface, an excellent tool for non-programmers.
Allows you to export your game to a variety of platforms such as iPhone, Android, Kindle, and HTML5.
Counts with a big community of users willing to assist you on forums.
Cons: Since you don't really code and instead you rely on its drag and drop system, you don't get to see the code itself, which is problematic since your understanding of your own game would never be as much if you coded it.
Overall: A clear idea of how game development works as well as game mechanics.
It was O.k. for a first timer.
Pros: I love the Drag and Drop features (because I cannot code), I love the assets you can add to it, and to be honest, adding your own assets to a project is always a good thing.
Small Download, doesn't waste a bunch of Hardware space.
Cons: Not pleased with the UI. They really need to update the tutorial videos and walkthrough on exactly how to create a UI and have it functional all throughout your project.
Overall: It was O.K for someone wanting to understand how a game is made.
Pros: The most interesting thing that GameSalad offers is the possibility of developing a videogame without the need to be an expert in programming. The drag-and-drop system allows you to create characters and / or levels quickly and intuitively.
Cons: What I liked least about GameSalad was the internet site that offers to upload the games online. It presents many delays when it comes to upload your game.
Pros: It is good to create a game on your phone and easily use it after. Pretty much creating the game of your dreams.
Cons: It does not have the best development tools. It is not as easy to use and you can get stuck on certain parts of it.


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Texas commit Jalen Milroe rallies Tompkins past Travis in playoff opener
Sports // High School
Adam Coleman , Houston Chronicle Nov. 14, 2019 Updated: Nov. 15, 2019 10:42 a.m.
Texas commit Jalen Milroe rallies Tompkins past Travis in...
1of25Tompkins Falcons quarterback Jalen Milroe (4) throws pass under pressure by Travis Tigers John Henderson (34) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
2of25Travis Tigers cornerback Jahvon O'neal (4) breaks up a pass in the end zone intended for Tompkins Falcons wide receiver Anthony Munoz (5) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
3of25Travis Tigers Mason Much (6) intercepts a pass intended for Tompkins Falcons Conner Kinslow (8) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
4of25Tompkins Falcons quarterback Jalen Milroe (4) throws a pass under pressure by Travis Tigers outside linebacker Jace Marsters (1) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
5of25Travis Tigers Eric Rodriguez (11) is sacked by Tompkins Falcons defensive end Tunmise Adeleye (94) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
9of25Travis Tigers Eric Rodriguez (11) scrambles under pressure by Tompkins Falcons nose guard Eti-ini Bassey (63) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
10of25Tompkins Falcons Conner Kinslow (8) catches a pass for a touchdown during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
11of25Tompkins Falcons fullback Garrett Mack (20) scores a touchdown during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
12of25Tompkins Falcons fullback Garrett Mack (20) catches a pass and runs for a touchdown during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
13of25Travis Tigers Eric Rodriguez (11) rushes for a touchdown during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
14of25Tompkins Falcons Pryce Powell (25) reacts after a tackle on fourth down during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
15of25Travis Tigers Eric Rodriguez (11) is forced to scramble under pressure by Tompkins Falcons defensive end Tunmise Adeleye (94) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
16of25Travis Tigers Eric Rodriguez (11) throws a pass during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
17of25Tompkins Falcons Marquis Shoulders (6) breaks a tackle by Travis Tigers cornerback Jahvon O'neal (4) and rushes for a touchdown during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
18of25Tompkins Falcons Marquis Shoulders (6) runs the ball during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
19of25Travis Tigers Kaelen Shankle (8) rushes for a touchdown during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
20of25Travis Tigers Eric Rodriguez (11) is tackled by Tompkins Falcons Dru Polidore (7) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
21of25Tompkins Falcons quarterback Jalen Milroe (4) tackles Travis Tigers outside linebacker Mickael Oliva (21) after an interception during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
22of25Tompkins Falcons quarterback Jalen Milroe (4) throws pass under pressure by Travis Tigers John Henderson (34) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
23of25Tompkins Falcons Marquis Shoulders (6) dives for a first down defended by Travis Tigers strong safety Cam Moore (7) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
25of25Tompkins Falcons Marquis Shoulders (6) runs the ball defended by Travis Tigers John Henderson (34) during the first half of the high school football playoff game between the Tompkins Falcons and the Travis Tigers at Mercer Stadium in Sugar Land, TX on Thursday, November 14, 2019. The Falcons lead the Tigers 21-14 at halftime.Photo: Tim Warner, Contributor
The unforgiving nature the state's toughest playoff bracket means at least one team will have a first-round loss tougher to swallow than most.
Tompkins avoided that disappointment — narrowly. The Falcons rode 28 unanswered points to a 35-28 win over Travis in the Class 6A Division I Region III bi-district playoffs Thursday at Mercer Stadium.
Travis had its own run with 14 unanswered in the last seven minutes of the game, nearly coming back to tie.
Travis (10-1) entered the game undefeated and riding high off a District 20-6A championship campaign in which it overcame stalwart Ridge Point. Tompkins (10-1) now has back-to-back double-digit win seasons with its only loss this year is to top-ranked Katy. The Falcons' rise continues after going 0-9 in 2017.
They did it with a defense that overcame a hot start from a vaunted Travis offense and the shifty Marquis Shoulders leading the running game. Tompkins junior quarterback and University of Texas pledge Jalen Milroe didn't let three first-half interceptions sully the game, either. He finished with three touchdown passes and a rushing score.
The last five minutes of the first half and opening five minutes of the second half saw Tompkins surge to its first lead of the night and wrestle control of what was a back-and-forth affair early on.
Tompkins did so on short drives, too. Milroe needed one play with his pass to Garrett Mack, who took it 28 yards to the end zone to tie the game at 14 with 7:21 left until halftime.
Tompkins took a 21-14 lead into halftime off Milroe's 46-yard touchdown pass to Conner Kinslow with 4:29 left in the second quarter to cap a three-play drive.
Tompkins' defense settled in between those scores. After Mack's touchdown, the unit forced a Travis punt, its second in as many drives. Highly coveted defensive end Tunmise Adeleye sacked Travis quarterback Eric Rodriguez the drive after Kinslow's score, which forced a third consecutive punt.
The turnaround for Tompkins' defense was impressive considering Travis opened with touchdowns on its first two drives — K.J. Shankle's 11-yard score and Rodriguez's 1-yard run after a 12-play drive that included four first downs.
And then there were Milroe's three first-half interceptions. He threw the third to Mason Muchaw after Adeleye's sack. Muchaw picked Milroe off twice in the first half, and the other interception went to Mickael Oliva on game's opening drive. It wasn't enough prevent Tompkins from taking over, though, and Milroe got into a groove in the second half.
He tossed his third touchdown of the night off a screen pass to Shoulders for a 35-yard touchdown with 7:35 remaining in the third quarter. The dagger seemingly came from Milroe's 1-yard touchdown run for a 35-14 lead with 8:17 remaining in the game. That easy run was made possible by his 39-yard pass to Anthony Munoz to the Travis 1-yard line.
Travis' offense woke up. Rodriguez, often the catalyst for the Tigers this year, scored on a 12-yard run with 7:16 remaining in the game. Travis' defense forced a stop, and Rodriguez tossed a 51-yard bomb to Jarrell Farr with just under four minutes left in the game to suddenly make it 35-28.
Tompkins awaits the winner of Lamar-Cypress Falls in the area round.
Adam Coleman
Follow Adam on:
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Adam Coleman joined the Houston Chronicle in April 2016 to cover Rice University and high school sports.
He previously worked for the Big Spring Herald and Houston Community Newspapers and also covered Houston high school and college sports as a freelance writer.
Coleman is a graduate of Westside High School and Texas Tech.
Chron's boys athlete of the week: Jordan Ivy-Curry, La Marque
Chron's girls athlete of the week: Amillion Fowler, George Ranch
2019 All-Greater Houston high school football teams
Tompkins defensive end Tunmise Adeleye transferring to IMG Academy
United edges out victory against North Shore
Clear Brook hires Duncanville DC John Towels III as new football head coach
Bryce Griggs leads Hightower over Manvel in overtime
Brandon Brown, the All-Greater Houston defensive player of the year


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The Loner is a 1988 American TV film directed by Abel Ferrara.

Cast
John Terry
Vanessa Bell

References

External links
The Loner at BFI
The Loner at IMDb

1988 television films
1988 films
Films directed by Abel Ferrara

redpajama_set_name: RedPajamaWikipedia


Mango rice is just one style of South Indian rice dishes among many different variations. Mango rice has a very unique flavor due to the tartness of the mangoes, the sweetness of the coconut, and the heat of the chilies all being mixed together. This is a simple but flavorful and satisfying light lunch!


You can view the photo that has been added by navigating using the left menu to MY PROXIO > Overview. In the top left corner, your picture will appear. Or to MY PROXIO > Home you picture will appear in the top right corner above the 'Activity Feed' (except many users who are with Keller Williams or KW GPS members and have a different version of ProxioPro - see here ).
You can also navigate using the left menu to NETWORK > Agents. In the 'Text Search:' field, enter your name and click the green arrow (as long as the country and other search criteria if you have entered any match that of your account), your profile will appear. Click your name to open your Agent Profile.
This is only because after you have clicked the Browse button, the information contained next to the Browse button will be the file name or in the field will be displaying the specific photo location where the image or file is from (i.e. on Internet Explorer C:\Users\Proxio\Desktop\Images\headshot.png which is an example of a file name and location that was on our hard drive. Note: your file and location will be different than this example).
Because the image is not stored there, the field will be blank, but your image is not lost.


Amazon Web Services (AWS), with its 'Walmartesque' everyday low prices strategy, has single handedly altered the enterprise software pricing model and has created the most important deflationary impact of this century.
The 'old tech' business model was to dominate an industry and then release mediocre upgrades at commensurate pricing points and with minimal worthwhile innovation. The 'new tech' model is to undercut the competition with material value added lower cost upgrades, which is exactly what AWS is doing. Amazon's low cost strategy has influenced many technology companies to also cut prices for their platform solutions, including Microsoft with its competing web platform, Azure, as well as Google Compute. In fact, you could argue that Windows 10 will be free for many users initially because of Amazon's influence.
We are being conditioned to expect to pay nothing or next to nothing for operating system platforms. I can't think of a more deflationary secular trend.
There are so many intriguing free Internet software products available now because of Amazon and there are no historical industry vertical precedents. The optimist in me believes that interest rates are low in part due to the deflationary impact of Amazon Web Services (AWS), and that the impact of low cost cloud platform computing will cause many verticals and software companies to cut prices in the years ahead and, hence, cause interest rates to remain close to historically low levels. AWS in 2015 is this generation's 1989 Berlin Wall tear down deflationary economic event.
Today, enterprise applications and operating system prices are plummeting thanks to Amazon acting as a price cut leader. This deflationary trend has started to accelerate as Microsoft and Google have started to also be price cut leaders by materially cutting the pricing points of their cloud service provider platforms, which are the platforms that some of the most disruptive companies in the world operate on top of. New companies are being created like Uber that charge much lower pricing points due to the inherent cost savings of low cost cloud platform solutions like AWS. This deflationary trend should continue for the foreseeable future. Many disruptive new companies don't use any software from old school tech companies like Oracle or Microsoft as there are widely available free (or lower cost) alternatives that run entirely on AWS. As a result, as consumers, we have so many opportunities to use technology products that now cost next to nothing to use or subscribe to (i.e., Netflix).
Why was the global economy booming in the '90s? It wasn't primarily because of the booming tech sector. Rather, it was mainly because the Berlin Wall fell in 1989 and a plethora of lower-cost, high-quality labor was unleashed from Eastern Europe; this was the reason we had low interest rates then, relative to the booming global economy.
AWS is today's equivalent. And the technology cost savings we're seeing today are commensurate with the deflationary labor cost savings in that era. Instead of the late, great Ronald Reagan prophetically telling Mr. Gorbachov to "Tear down this wall," Amazon has forced the entire enterprise software market to dramatically reduce prices around the walled garden of ridiculously high-margin software prices. Only it was Jeff Bezos telling Mr. Ballmer in 2005, when AWS was released, to "Tear down this wall." The deflationary impacts are remarkably similar.
How is AWS deflationary? Your monthly cable bill is now more than 50 percent cheaper. Your hotel fees are more than 50 percent cheaper. Your server computing bill is more than 50 percent cheaper. The IT cost to start a business is now more than 50 percent cheaper. The list goes on.
Netflix is profitable and is dirt cheap at only $7.99 per month, with superb proprietary content, because Netflix runs on AWS. AirBnB allows us to pay next to nothing for hotels because AirBnB runs on AWS. Dropbox has cut our company's server costs by more than 50 percent because it runs on AWS. As AWS continues to materially cut the pricing point of its platform and applications, we can expect more companies to cut prices and/or new companies to emerge that compete with, and materially disrupt, old school companies that have dominated their respective industries for decades. It's astonishing how much better Netflix's content is today versus a decade ago when its pricing point was much higher; thanks in large part to Netflix running on AWS.
Under Ballmer, Microsoft only cut the price point of Windows three times since it was launched more than 20 years ago. By contrast, Bezos has cut the price point of AWS close to an astonishing 50 times in less than 10 years.
But now, under new CEO Satya Nadella, Microsoft's competing product to AWS, Microsoft Azure, is not just a price cut follower, but also a price cut leader. Google's superb cloud platform, Google Compute, is also now a price cut leader. We have three unbelievable cloud service providers all aggressively cutting prices.
These platforms are the most important cloud operating systems and, thanks to AWS, the deflationary impact of the aforementioned platform price cuts is staggering and unprecedented. This is not an irrational exuberance event.
There is no historical deflationary precedent in any other industry. The impact is commensurate with Ford, GM, and Toyota cutting prices on cars 50 times in 10 years. Or Marriott, Holiday Inn, and Ramada cutting hotel prices 50 times in 10 years. Or General Electric, Sub-Zero, and Maytag cutting prices on their appliances 50 times in 10 years.
In the past, companies were slaves to the enterprise software giants with their "one neck to choke" strategy. Conglomerates like Oracle, with their patched together acquired vertical offerings from the hardware layer (Sun Microsystems), to the middleware layer (BEA) to the enterprise resource planning layer (PeopleSoft and others), would charge hefty annual maintenance fees. Never again. AWS and lower priced deflationary cloud computing options have finally disrupted this model. In the years ahead, we will continue to see cloud service provider platform giants like Amazon, Microsoft, and Google continue to cut prices, furthering the most deflationary event we have seen since that historic event in 1989.
Chris Haroun is a partner at VC firm ARTIS Ventures.