David Makovsky is the Ziegler distinguished fellow at The Washington Institute and director of the Project on Arab-Israel Relations. He is also an adjunct professor in Middle East studies at Johns Hopkins University's Paul H. Nitze School of Advanced International Studies (SAIS). In 2013-2014, he worked in the Office of the U.S. Secretary of State, serving as a senior advisor to the Special Envoy for Israeli-Palestinian Negotiations.
Author of numerous Washington Institute monographs and essays on issues related to the Middle East Peace Process and the Arab-Israeli conflict, he is also coauthor, with Dennis Ross, of the 2009 Washington Post bestseller Myths, Illusions, and Peace: Finding a New Direction for America in the Middle East (Viking/Penguin). His 2017 interactive mapping project, "Settlements and Solutions," is designed to help users discover for themselves whether a two-state solution is still viable. His 2011 maps on alternative territorial solutions to the Israeli-Palestinian conflict were reprinted by the New York Times in the paper's first interactive treatment of an op-ed. His widely acclaimed September 2012 New Yorker essay, "The Silent Strike," focused on the U.S.-Israel dynamics leading up to the 2007 Israeli attack on Syrian nuclear facilities.
Mr. Makovsky is a lifetime member of the Council on Foreign Relations and the London-based International Institute for Strategic Studies. His commentary on the peace process and the Arab-Israeli conflict has appeared in the New York Times, Washington Post, Los Angeles Times, Wall Street Journal, Financial Times, International Herald Tribune, Chicago Tribune, Foreign Affairs, Foreign Policy, and National Interest. He appears frequently in the media to comment on Arab-Israeli affairs, including PBS NewsHour.
He has testified before the full U.S. Senate Committee on Foreign Relations, the full U.S. House of Representatives Committee on Foreign Affairs, and on multiple occasions before the House of Representatives Committee on Foreign Affairs Middle East Subcommittee.
In last several years, he has made over 120 visits to American college campuses to discuss the Israeli-Palestinian conflict. He has done a TEDx talk on this issue for the college audience.
Before joining The Washington Institute, Mr. Makovsky was an award-winning journalist who covered the peace process from 1989 to 2000. He is the former executive editor of the Jerusalem Post, was diplomatic correspondent for Israel's leading daily, Haaretz, and is a former contributing editor to U.S. News and World Report. He served for eleven years as that magazine's special Jerusalem correspondent. He was awarded the National Press Club's 1994 Edwin M. Hood Award for Diplomatic Correspondence for a cover story on PLO finances that he cowrote for the magazine.
In July 1994, as a result of personal intervention by then Secretary of State Warren Christopher, Mr. Makovsky became the first journalist writing for an Israeli publication to visit Damascus. In total, he has made five trips to Syria, the most recent in December 1999 when he accompanied then Secretary of State Madeleine Albright. In March 1995, with assistance from U.S. officials, Mr. Makovsky was given unprecedented permission to file reports from Jeddah, Saudi Arabia, for an Israeli publication.
A native of St. Louis, Missouri, Mr. Makovsky received a bachelor's degree from Columbia University and a master's degree in Middle East studies from Harvard University.


text:
Witness to Guantanamo
Story of GTMO
About WTG
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Redouane Chekkouri
Charges brought:
Redouane Chekkouri [also identified as Echekkouri and Radwan al Shakouri] was born in February 1972 in Asafi, Morocco. Chekkouri and his brother moved to Jalalabad, Afghanistan, where they worked for the Moroccan Islamic Fighting Group. After 9/11, Chekkouri was captured by the United Islamic Front for the Salvation of Afghanistan, which transferred him to U.S. custody. He was sent to Guantanamo Bay on April 30, 2002. Chekkouri was released to Morocco on July 31, 2004. Upon returning to Morocco, Chekkouri (along with four other ex-Guantanamo detainees) was put on trial for charges related to terrorism, but was eventually acquitted in 2007.
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redpajama_set_name: RedPajamaCommonCrawl


It's that time of year again. Spring is in the air and Western Australia is alive with a spectacular display of wildflowers. The season for flower lovers has hit, and Perth and surrounding areas are covered with more than 12,000 species for your eyes and nose to soak up.
WA's beauty can be associated with many things. Paradise beaches, plentiful sunshine hours, pockets of untouched wilderness to explore and some of the world's greatest botanical wonders. The wildflower season begins in the state's north early June. And as the weather warms up and the sun-filled days invite us to drift outside, it sweeps down through Perth to the south coast and lasts until the end of spring. An extended 4-month period of absolute bliss. It's one of WA's hottest tourist attractions. Not just on a national level either, but a worldwide magnetism that brings visitors from around the globe.
This place is simply magical and a must for all flower enthusiasts – especially extreme lovers of tulips like myself! The tulip season blooms until September 25th and the best place to get lost in their beauty is at Araluen Botanic Park (ABP). Don't believe me?
Check out this stunning picture taken by Perth Munchkin on her last adventure there! ABP is renowned for its 59 hectares of breathtakingly beautiful gardens. It's not just all tulips either, but a diverse range of exotic plants that will keep you wanting to explore for hours.
Add it to Your Calendar: ABP celebrates its annual Springtime Festival 19th August – 25th September when everything is in its full bloom. This is the best time to witness more than 125,000 tulips carpeting the park grounds in vivid bursts of colour. See more details about how to get there and things to do at Araluen here.
Famous for being a hotspot of wineries, restaurants and breweries, The Swan Valley is rich with wildflower species throughout the season. And it's only a 30 min drive out of Perth city. What better way to indulge in some of the country's tastiest wines and food, complete with a backdrop of brilliantly coloured flowers and the lush greens of the valley.
Whether you prefer to sit back with a glass of vino in one hand gazing over the blooms, or venture on some of the valley's extensive walking trails, there's something to enjoy for everyone.
To Do: Noble Falls Walk Trail which is home to orchids, trigger plants, verticordias, hakeas, grevilleas and petrophiles.
In the heart of Perth lies one of WA's ultimate settings for wildflowers – Kings Park. Perched high above Perth city overlooking the Swan River with magnificent views, Kings Park is home to the biggest display of wildflowers in the state.
Throughout the season, these beautiful parklands boast 1,7000+ native species of wildflowers and 3,000+ varieties of flora unique to WA. See more about Kings Park here.
To Do: Walk on the wild (flower) side! Bring the family and take a walk along the treetops along the Lotterywest Federation Walkway or experience the Botanic Garden Discovery Walk. Kings Park is full of free activities including guided walks, wildflower festivals and entertainment including live music.
If colourful countryside drives, rolling hills and winding streams make you excited, then Avon Valley is a must in spring. Stretching from Beverly through to New Norcia and Victoria Plains, the area covers Chittering, Goomalling, Northam, Toodyay and York too – all of which provide the perfect backdrop for wildflower getaways.
Head there for a day trip from Perth or a weekend adventure, and satisfy your thirst for rich history, local attractions and the picturesque display of wildflowers.
To Do: Road trip along Traverse Talbot West Road in York which takes you through the attractive woodlands and flower displays. While you're in York, it's worth checking out the haunted old York hospital for a ghostly abode!
250km east of Perth, The Wheat Belt joins in for the wildflower season with 980 species of colourful goodness. You can extend the wildflower season a little longer here, as they're on display from July to October lapping up the rainfall. Orchids thrive in the area, as well as multiple species of acacias, eucalyptus and heathland plants. Throughout WA's golden outback, you can experience the wildflowers in all their beauty on various walking trails and drives.
To Do: Add Wave Rock Trail to your itinerary for an lively showcase of wildflowers. The Everlastings trail will impress too, as well as the Granite Loop.
Explore along the Coral Coast for wildflowers that bloom all year round and head to Kalbarri National Park. Between June and October is when the magic truly amplifies. The dry sand plains transform into a colourful extravaganza during this time and native wildflowers bursting with character. Keep your eyes peeled for the Kalbarri Spider Orchid and delve deep in to the gorges and coastal cliff tops for native flora.
To Do: Take a weekend (or a week) off from the daily bustle and camp at the National Park for the supreme experience.
Head over to Rotto on the ferry, soak up and the sun and be a part of one of WA's popular playgrounds. The island is home to the Blue Rottnest Daisy and 1,500 additional native species of pretty wildflowers. You'll also find adorable Quokkas roaming around and attractive peacocks amidst the action. Not to mention, plenty of water sports, relaxing and exploring to achieve.
To Do: Trek along the 50km Wadjemup Bidi Trail for a scenic tour of the island's wildflowers. The walk is split into five sections, each boasting their own display of blooms and culturally inspired landmarks along the way.
Packed full of prettiness, adventure and relaxation, Serpentine National Park is the place to be this spring. Here, the bushland comes alive with wildflowers including red and green kangaroo paws including masses of brightly coloured orchids and blue lace flowers. Variety is at its peak and there are multiple walking trails to explore.
To Do: Drive, walk or wind through the Darling Range and head to Serpentine Dam for a swim. Along the way, you'll bear witness to lush forests and array of stunning flora.
This article is written by Emma Sayce, the owner and senior florist at A Touch of Class Florist – a Perth based boutique online flower shop with a difference, sourcing only the freshest flower arrangements daily with delivery 6 days a week. You can catch A Touch of Class on Facebook and Instagram too.
Thanks Julie, it's a gorgeous time of the year.
It's the most colourful time of the year.
The wheatbelt has to be my favourite but maybe that is because it is my home!
It must be beautiful at the moment. I love WA in September.


Didn't see any rain clouds when we left the house.
Followed by strong gusts, blackness and pelting rain.
Under a bright (remarkably cloudless) sky and in a waveless pond-like gulf.
Fifty miles away over Ft Myers.
Typical summer afternoon at the beach.


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Q: How to Serialise a List of instance nested within a class? I am trying to save a class into a file with serialization, it work for all proptiety but fail to Serialize nested class.
My class is suppose to represent a Task with a name,description ,... and it can be compose itself by subtask which is represent by a List of task
I have try to write [Serializable] before my list like explaine here:  Serialize Nested Classes in c#?
but I get this error: "Attribute 'Serializable' is not valid on this declaration type. It is only valid on declarations."
[Serializable()]
public class t_Task
{
   private string nom;
   private string description;
   [Serializable]
   List<t_Task> subTask;
}

How to get all class in the list also serialize please ?
Edit: I am serializing using a methode found here: http://blog.danskingdom.com/saving-and-loading-a-c-objects-data-to-an-xml-json-or-binary-file/
public static void WriteToBinaryFile<T>(string filePath, T objectToWrite, bool append = false)
{
    using (Stream stream = File.Open(filePath, append ? FileMode.Append : FileMode.Create))
    {
        var binaryFormatter = new System.Runtime.Serialization.Formatters.Binary.BinaryFormatter();
        binaryFormatter.Serialize(stream, objectToWrite);
    }
}

Then i call it with a methode close to this one
public void Save()
        {
            GesionBinaryFileIO.WriteToBinaryFile<t_Task>(PathToFile, this);
        }

A: [Serializeable] is not allowed on fields/properties and only needs to be put on the class.  Your class should be serializeable just looking like this:
[Serializable()]
public class t_Task
{
   private string nom;
   private string description;
   List<t_Task> subTask; // Removed the [Serializeable] attribute
}

It is important to note that your List<t_Task> is not a nested class (it is just a regular class field), so the link you are referencing is not actually related to your problem.
[Serializable] is a relatively old method of marking for serialization. I would reference the Microsoft documentation on SerializeableAttribute to see how your code could work.
Here is a sample based upon the Microsoft article I linked:
using System;
using System.Collections.Generic;
using System.IO;
using System.Runtime.Serialization.Formatters.Binary;

namespace ConsoleOne
{
    [Serializable()]
    public class t_Task
    {
        private string nom = "test"; // Added for test data.
        private string description = "desc"; // Added for test data
        List<t_Task> subTask = new List<t_Task>();

        public void AddTask()
        {
            this.subTask.Add(new t_Task());
        }

        public override string ToString()
            => $"{nom}-{description}-{subTask?.Count}";
    }

    class Program
    {
        static void Main(string[] args)
        {
            var task = new t_Task()
            {

            };

            task.AddTask();
            task.AddTask();

            // Opens a file and serializes the object into it in binary format.
            Stream stream = File.Open("data.xml", FileMode.Create);

            BinaryFormatter formatter = new BinaryFormatter();

            formatter.Serialize(stream, task);
            stream.Close();

            //Empties obj.
            task = null;

            //Opens file "data.xml" and deserializes the object from it.
            stream = File.Open("data.xml", FileMode.Open);
            formatter = new BinaryFormatter();

            //formatter = new BinaryFormatter();

            task = (t_Task)formatter.Deserialize(stream);
            stream.Close();

            Console.WriteLine($"{task}");
            Console.ReadLine();
        }
    }
}

Note: There are many other avenues for serialization in .NET that are a bit more modern.  It may be worth reading about these as well. However, if you are only interested in a simple binary format then the above information should be sufficient.

*

*Serialization in .NET

*Json.NET

redpajama_set_name: RedPajamaStackExchange


Poly Bridge is a highly addictive puzzle game developed by Dry Cactus Limited. Currently, the game is available for Android and iOS; you can download and install it for free. However, if you want to unlock all the features in the game, we recommend you use the Poly Bridge Mod APK we provide in this article. In the game, players will play an architect to build bridges, which help to facilitate traffic between villages. Gameplay may sound simple, but building a bridge well enough to go through the challenges of the game is not easy at all. You need to have a basic understanding of physics, as well as a little luck.
It is not easy to create a bridge across the river. You need to use the wooden bars to support the force, use the cable and place them in the most suitable position. The larger the means of transport, the bridges must be built more solidly. Pay attention to your budget. Just like in practice, the cost of building each bridge is limited. You need to use the resources that are as economically feasible as possible.
However, to ensure that transportation does not fall into the river when crossing the bridge, you should use good enough resources and reasonable. Remember, do not waste too much, but do not overdo it. If you exceed the specified amount, press the undo button to return to the previous step. After completing the bridge, click the Start Simulation button on the top right corner of the screen to bring the bridge into the test. If successful, you will go through the stage and come up with new challenges. If it fails, use the undo button to change a certain structure of the bridge or click on the trash can icon to start rebuilding from scratch.
The task is usually to build a road by connecting 2 Static Joints. Or a bit more complicated. However, the challenges will come after the first 10 levels.
At this time, the vehicle over the bridge will be heavier and it will require players to build more support. Remember, triangular structures are the most stable to keep your bridge active.
In each stage, you need to build bridges to serve different vehicles. It is important to find out what the number of vehicles and types of vehicles are. It's a waste of time if you have to focus on designing a solid bridge just to get a motorbike through. There are large payloads that require players to build more support systems. In other cases, your bridge needs to be equipped with a self-splitting feature when passing ships.
At present, Poly Bridge brings you more than 100 levels to conquer. We bet that to finish them, you will spend a lot of time. So, we bring you the latest mod of this game, it helps you complete all of the challenges in the game easier.
Using tools will make the bridge construction easier. Poly Bridge provides useful features to help you build bridges that are simpler. Area Selection Tool will help you select a part or whole bridge. Move Joint Tool adjusts the position of the Bridge Joints. The Suspension Bridge is one of the most sustainable bridges. So, do not forget to use the Tracing Tool to build it when you can afford it.
In Poly Bridge, sometimes you will face difficulties. At times, you have made a lot of changes to the bridge material or changed the structure, the length of the bars, but you still can not complete the game. There is a tool that will help you overcome this. You just have to switch to slow motion mode, which can help you find out what part of the bridge is weakest and need to improve. Click the Start Simulation button and drag the slider to the right of the screen to adjust the view speed. Keep in mind the broken position of the bridge then go back and add support for that point.
If you've ever dreamed of becoming a bridge architect then try playing Poly Bridge mod. The game is a collection of many physics and geometry puzzles to challenge the mind and creativity of the player. The puzzle system has an increasing difficulty enough that you can conquer it. To create a perfect and sustainable bridge, you will sometimes have to play again and again and try different ways of building. The undo, redo tools will help you easily edit your design. If you have any questions about the game, please leave a comment below.


text:
Season preview: What to expect from Auburn baseball in 2019
A look at what the Tigers will have on the mound, in the field and at the plate when they open the season against Georgia Southern at Plainsman Park.
Season preview: What to expect from Auburn baseball in 2019 A look at what the Tigers will have on the mound, in the field and at the plate when they open the season against Georgia Southern at Plainsman Park. Check out this story on montgomeryadvertiser.com: https://www.montgomeryadvertiser.com/story/sports/college/auburn/2019/02/14/auburn-baseball-season-preview-2019-butch-thompson-casey-mize-sec-omaha-daniel-burns-holland-julien/2869483002/
Josh Vitale, Montgomery Advertiser Published 11:55 a.m. CT Feb. 14, 2019 | Updated 4:17 p.m. CT Feb. 14, 2019
AUBURN — It took some time for Steven Williams to put that play behind him.
You know the one: Bottom of the 11th inning, no outs in Game 3 of a Super Regional in Gainesville, Florida. Auburn's star true freshman right fielder got a glove on the line drive Gators left fielder Austin Langworthy sent hurtling his way. Had Williams caught it, the game would have continued. The Tigers might have won.
But it was Florida that celebrated that night. The ball bounced off Williams' glove and over the right-field wall for a walk-off home run. The Gators went to Omaha, Nebraska, for the College World Series, and the Tigers went home to think about what could have been.
On Friday, eight months and four days later, Auburn will begin the 2019 season against Georgia Southern. The play that ended the team's 2018 season may no longer be forefront on players' minds, but what it represents still is.
"We know that we've been one pitch away from going to Omaha, one run away from going to Omaha," junior infielder Conor Davis said. "I think that we'll be able to push ourselves and, hopefully, break through that door coach always talks about and go to Omaha."
The team that takes the field Friday at Plainsman Park will look different than the one that did all those months ago at McKethan Stadium. Five everyday starters in the field and three key arms are gone, including ace and No. 1 overall baseball draft pick Casey Mize. Eighteen players return, but the other half of the roster is made up of newcomers.
But there are still high hopes for that group. Auburn starts the season ranked No. 20 in the USA Today coaches poll. It was picked to finish fourth in a deep SEC West headlined by LSU, Ole Miss and Arkansas.
"I don't think we should take a backseat to anybody," head coach Butch Thompson said. "I think teams should have to take a look at us as the team that they have to play as well. I think we'll have a chance to win every baseball game we play this coming season."
Here's what to expect from Auburn in 2019:
Auburn baseball coach Butch Thompson looks on during a preseason practice at Plainsman Park. (Photo: Wade Rackley/Auburn Athletics)
ON THE MOUND
Auburn has two front-line starters leading the rotation during each of the past two seasons. In 2017, it was Keegan Thompson and Mize. In 2018, it was Mize and Tanner Burns. The hope is that Burns and Davis Daniel can provide the same punch this season, though Mize left some big shoes to fill after going 10-6 with a 3.30 ERA and 156 strikeouts over 114 1/3 innings last season.
Burns looks up to the task after going 7-4 with a 3.01 ERA during an SEC All-Freshman campaign last season, especially if he can take the same sophomore leap Mize once did. A bigger leap will be required of Daniel, who struggled as the No. 2 starter behind Mize last season before eventually being moved to the bullpen.
But it's the adjustments Daniel made after that switch that gave Auburn enough confidence in him to name him the team's opening day starter Friday against Georgia Southern — after pitching to a 5.66 ERA over his first 14 appearances, he complied a 2.60 mark over his final five.
"We think he's ready to take the reins, because that's a big slot to fill from what we've had in that slot the last two years," Butch Thompson said. "But I do think that both are capable of doing it, and I think that would be the positive nature of where we're at with those two guys, is that I think they're 1A and 1B."
Burns will follow Daniel on Saturday with redshirt junior Kyle Gray filling out the weekend rotation on Sunday. The left-hander went 7-1 with a 2.73 ERA and 91 strikeouts over 66 innings at Blinn Junior College last season.
Thompson said that third spot could have gone to a number of different pitchers, which showcases the depth the Tigers have on the mound even after losing Mize and key bullpen pieces Calvin Coker and Andrew Mitchell.
Sophomore left-hander Jack Owen (2-2, 5.97 ERA) will start Auburn's first midweek game on Tuesday. McClennan Community College transfer Bailey Horn (7-0, 3.86 ERA in 2017) could be stretched into a starter, but the staff is bringing him along slowly as he is only 10 months removed from surgery.
Sophomore right-hander Cody Greenhill was also given a look, but he threw to batters for the first time only last weekend. Thompson said he will remain in the bullpen and be the first pitcher the Tigers turn to with a game on the line after he saved five games with a 1.24 ERA last season.
Other pitchers Auburn will use in relief include returner Elliott Anderson (5-0, 3.64 ERA) and true freshmen Richard Fitts, Brooks Fuller, Will Morrison, Carson Skipper and Garrett Wade, who each bring a different skill set — Fitts is a hard-throwing right-hander, Fuller a competitor that could be used in the late innings, Morrison a lower-arm-slot thrower, Skipper a soft-tossing lefty, and Wade, the reigning Gatorade Alabama Player of the Year out of Hartselle, a specialist with "as much swing-and-miss as anybody" on Auburn's staff.
Auburn shortstop Will Holland. (Photo: Wade Rackley/Auburn Athletics)
Auburn returns a lot of familiar names among its position players, but its only constants in the field will be junior Will Holland, who enters his third season as the starting shortstop; and sophomore Williams, who is the returning starter in right field.
Holdovers Davis and Edouard Julien will also continue to play significant roles, albeit at different positions defensively. Davis, who played mostly left field last season, will team up with junior college addition Rankin Woley to replace Josh Anthony at first base, with the other likely serving as the designated hitter when not in the field. Julien, who served almost exclusively as the designated hitter last season, has moved to third base to replace Brendan Venter.
"We've been committed to that for a while," Thompson said of Julien, who started only 15 games in the field last season. "(Assistant coach) Karl Nonemaker has just spent every single day trying to make that happen."
Sophomore Judd Ward will take over as the starter in left field after serving in a part-time role last season. The rest of the starting roles will go to newcomers — true freshmen Ryan Bliss will take over for Luke Jarvis at second base and Kason Howell for Jay Estes in center field; and junior college addition Matt Scheffler (as well as returning reserve Chase Hall) for Brett Wright at catcher.
"Matt Scheffler has worked as hard as anyone in our program," Thompson said. "I think he's skilled enough, which I think is very important for this level. And then three, I think he's a servant. I think when he's on the field, he's really thinking, 'How can I make that guy on the mound 10-15 percent better.' Not everybody can do that."
Auburn second baseman Ryan Bliss takes batting practice. (Photo: Wade Rackley/Auburn Athletics)
The departures of Anthony, Venter, Jarvis, Estes and Wright give Auburn a few significant holes to fill in the lineup. Those five players combined to total 30 home runs and 191 runs, which equaled 41.1 and 45.2 of the team's totals, respectively.
The good news for the Tigers, though, is that while all those players were key cogs in the offense, none were the focal point. Julien, Holland and Williams were, and they all return with a chance to build on hugely successful seasons.
Julien hit .275 with a team-leading 17 home runs and 69 RBIs, the latter total breaking Frank Thomas' program record for a freshman. Holland hit .315 with 12 home runs and 52 RBIs, and Williams .291 with 12 homes runs and 51 RBIs.
But what will ultimately determine how successful Auburn's offense is this season is how the newcomers fill in around the returning contributors, which also include Davis (.268, two home runs, 34 RBIs) and Ward (.250, eight RBIs). The Tigers had great success with that last season, when Venter, Wright, Julien and Williams were all newcomers, and the hope is that this year's group can provide similar punch.
There is plenty to like from those players' junior college and high school resumes. Howell, a 20th-round baseball draft pick by the Boston Red Sox, hit .462 with six home runs and 39 RBIs as a senior at Liberty Christian (Texas) School. Bliss, a 30th-round pick by the Red Sox, stole 64 of 66 bases in his career at nearby Troup County (Georgia) High. Scheffler hit .369 with 15 extra-base hits and 22 RBIs at Pierce (Washington) Community College, and Woley .460 with 38 extra-base hits and 98 RBIs at Chattahoochee Valley Community College.
"There is a ton of potential in the lineup," Williams said. "We've got some new guys in there that can really swing it. I'm excited to see how they're going to react on game day like the freshmen Kason and Ryan and how they're going to react out there. The potential is sky high. We've got a lot of guys that can swing the bat. I'm excited to see it."
PROJECTED OPENING DAY LINEUP
LF Judd Ward
SS Will Holland
RF Steven Williams
DH Rankin Woley
3B Edouard Julien
1B Conor Davis
2B Ryan Bliss
CF Kason Howell
C Matt Scheffler
Josh Vitale is the Auburn beat writer for the Montgomery Advertiser. You can follow him on Twitter at @JoshVitale. To reach him by email, click here.


text:
International Summit on Human Gene Editing: No Recommendation for Ban or Moratorium on Germline Gene Editing Research
The International Summit on Human Gene Editing, hosted by the National Academies of Science and Medicine (NAS, NAM) and international partners, has just concluded a 3-day meeting (archived webcast available here). This summit was called following the rapid dissemination of human gene editing research using the CRISPR/Cas 9 technology (see earlier posts here and here). The impact of this technology cannot be understated:
The rapid development and widespread adoption of easy-to-use, inexpensive and effective genome-editing methodologies has changed the landscape of biology. The simplicity of the CRISPR–Cas9 system allows researchers and students to make precise changes to genomes, thereby enabling many experiments that were previously difficult or impossible to conduct.
Widespread concern over possible attempts to engineer the human germline (perform gene editing on embryos or gametes for reproductive purposes) led to calls for caution or even a research moratorium (see here). At the conference this week, panels discussed the current technical state of human gene editing, existing and potential governance structures, international perspectives, and social consequences of the technology. The most controversial application of human gene editing – germline editing creating heritable genetic changes – was central to many of the discussions, and the conference oscillated between considering the legitimacy of germline editing and considering the arguably more mundane regulatory control of somatic gene editing. The conference coordinating committee has released a consensus statement that endorses further research on both somatic and germ-line gene editing, subject to existing regulations and oversight mechanisms. The full statement is here. I reproduce the portion of that statement that focuses on the hotly contested issue of germline gene editing:
3. Clinical Use: Germline. Gene editing might also be used, in principle, to make genetic alterations in gametes or embryos, which will be carried by all of the cells of a resulting child and will be passed on to subsequent generations as part of the human gene pool. Examples that have been proposed range from avoidance of severe inherited diseases to 'enhancement' of human capabilities. Such modifications of human genomes might include the introduction of naturally occurring variants or totally novel genetic changes thought to be beneficial.
Germline editing poses many important issues, including: (i) the risks of inaccurate editing (such as off-target mutations) and incomplete editing of the cells of early-stage embryos (mosaicism); (ii) the difficulty of predicting harmful effects that genetic changes may have under the wide range of circumstances experienced by the human population, including interactions with other genetic variants and with the environment; (iii) the obligation to consider implications for both the individual and the future generations who will carry the genetic alterations; (iv) the fact that, once introduced into the human population, genetic alterations would be difficult to remove and would not remain within any single community or country; (v) the possibility that permanent genetic 'enhancements' to subsets of the population could exacerbate social inequities or be used coercively; and (vi) the moral and ethical considerations in purposefully altering human evolution using this technology.
It would be irresponsible to proceed with any clinical use of germline editing unless and until (i) the relevant safety and efficacy issues have been resolved, based on appropriate understanding and balancing of risks, potential benefits, and alternatives, and (ii) there is broad societal consensus about the appropriateness of the proposed application. Moreover, any clinical use should proceed only under appropriate regulatory oversight. At present, these criteria have not been met for any proposed clinical use: the safety issues have not yet been adequately explored; the cases of most compelling benefit are limited; and many nations have legislative or regulatory bans on germline modification. However, as scientific knowledge advances and societal views evolve, the clinical use of germline editing should be revisited on a regular basis.
As reported by David Baltimore, chair of the conference committee, the members did not recommend either a ban or a moratorium on research into germline gene editing, but they state that any use of gene editing in reproduction at this time would be "irresponsible." In the U.S., the NIH has already ruled out federal funding for such research:
However, NIH will not fund any use of gene-editing technologies in human embryos. The concept of altering the human germline in embryos for clinical purposes has been debated over many years from many different perspectives, and has been viewed almost universally as a line that should not be crossed.
The NAS contemplates ongoing public engagement with the controversies raised by human gene editing, in the form of an upcoming formal NAS study and the establishment of a publicly accessible forum to continue the discussion. More analysis of the conference and the effects on the current research climate will be posted here.
Labels: CRISPR, Gene Editing, NAS, NIH, Reproductive Technologies
Federal Circuit Denial of Rehearing for Prenatal D...
International Summit on Human Gene Editing: No Rec...


Responsible Care has long been viewed as industry's commitment to world-class environmental, health, safety and security performance. As Responsible Care enters its fourth decade, ACC and its members are leveraging the foundation laid by Responsible Care to grow and enhance our industry's contributions to sustainability.
Join us for the 2019 Responsible Care & Sustainability Conference & Expo to explore how Responsible Care and ACC's Sustainability initiatives are helping stakeholders integrate the three components of sustainability - economic, environmental, and social - into their core business practices.
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Register by March 21, 2019 and save $200 by taking advantage of our early-bird discounts!
The chemical industry plays an essential role in cultivating circularity and sustainability. While progress will take time, stepwise advances include prioritizing resource conservation and efficiency and driving innovations in products and processes. This session will provide an overview of industry's engagement on this important issue and how leading organizations are implementing sustainability programs that enhance circularity.
ACC recently published an updated version of the Responsible Care Management System® (RCMS) Technical Specification, featuring enhancements to organizational planning and training requirements, among others, and ACC implemented changes to the certification process and Responsible Care logo usage guidelines. This session will provide an overview of these changes and help participants understand how these changes may affect how their companies implement Responsible Care.
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Steak and veggie Meal Prep ON FLEEK .. I was going go to with curry again this week because last weeks meal was so damn good but I went with steak and veggies this week. I didn't dip everything in garlic butter this time to ease up on the calories. This weeks meals is enough for two portions to split throughout the day if you're keeping calories low or just wanting to spread out the food since eating the whole tray in one sitting will be a bit too much. Trust me, I'm notorious for eating excessive amounts of food and this combination of food will keep you full for awhile. Next week I'll probably do a thai curry or something. #PokemonGo is still eating up most of my free time. I just can't stop! Thanks for all your support!! I'll be coming back to reality soon…I think.
I buy all the food from Costco except for the seasoning. I get all the seasoning from whole foods and on Amazon. Some of our favorite seasonings are Primal Palate, Caribeque, and TeenyTiny Spice.
Where do you like to grocery shop? Tell us in the comments below.


On restarting, they splashed through a stream that flowed across the road.
I regained my state-room and waited, watch in hand, for the jerk of restarting.
Before they could capture the aviator, he succeeded in restarting his machine and in making his escape to the German lines.
This is a very tedious interruption, and the stopping and restarting of the ship very incommodious.
The second point concerns the resettlement of returned soldiers upon the land and their restarting in business.
Nor dare he stop again and subject the animals to the cruel effort of restarting.


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ITC Notification: Credit Limited Up to 20% Not Reflected in GSTR 2A
Amendment Impact Input Tax Credit
Now with this insertion of this sub-rule (4) under the CGST Act, the reconciliation of invoices and GSTR-2A form is mandatory, which will increase the monthly workload of taxpayers professionals or practitioners. Keeping a close eye or following up with suppliers about the uploading of invoices will also become mandatory for taxpayers claiming ITC.
The reckless reporting of B2B transactions as B2C by suppliers due to this amendment will result in non-appearance of invoices/debit notes in the recipient's GSTR-2A. Such a time lag will also make it difficult for them to claim ITC.
Taxable entities with few suppliers belonging to the MNC/organized sector won't be largely affected due to such an amendment. Reconciliation and follow-up will be easy for such players. However, taxable persons at lower belts with multiple vendors, especially in the FMCG sector, will find it difficult to comply with such an amendment.
CBIC Notification for CGST Rules, 2017
"(4) Input tax credit to be availed by a registered person in respect of invoices or debit notes, the details of which have not been uploaded by the suppliers under sub-section (1) of section 37, shall not exceed 20 per cent of the eligible credit available in respect of invoices or debit notes the details of which have been uploaded by the suppliers under sub-section (1) of section 37." Check Notification
Issues that Need to be Addressed
Addressing the Mismatch Problems Between GSTR-1 and GSTR-2A:
As we know, GSTR-2A gets auto-populated based on the detailed filled in GSTR 1 from suppliers end even after passing of due date. Hence, a mismatch between invoices and updated GSTR 2A is common, making reconciliation challenging for taxpayers.
Quarterly GSTR-1 Filings by Suppliers:
The taxpayers with annual turnover less than INR 1.5 crores file quarterly returns as per GST rules. However, with Monthly ITC claiming via GST 3B return form, it is nearly impossible for anyone to reconcile monthly invoices with GSTR 2B (as it would be generated after the given quarter).
Miscellaneous Problems:
The newly inserted sub-rule has left ambiguity in terms of scenarios when the supplier needs to report invoice/debit note for a given tax period. Whether such amount will be a part of the eligible ITC for a reported tax period is still unclear. ITC can be taken as a credit of a FIFO basis or as a pro-rata basis, is also not clarified.
Legal Difficulties on Input Tax Credit
Based on Section 164(1), the government has the authority to form rules for applying the provisions of CGST Act 2017, on the basis of the recommendation of the Council. However, the provision of the CGST Act: section 16 and section 17 is not a part of such an embargo. So, invoking such restrictions by a rulemaking make is certainly not an accurate legal position. Also, it is very clear that a rule cannot override the provisions of the Act.
In actuality, Article 14 of the Constitution of India formed by Delhi High Court has been violated by the insertion of sub-rule(4) in CGST Act as it does not offer clarity between bona fide cases (the mismatch is due to the fault of the supplier) and non-bonafide cases (bogus credit claim by the recipient).
The last legal difficulty related to the insertion of new sub-rule in Act includes violation of the basic principle of law viz., Lex non-cognit ad impossibly, i.e., the law should not compel a person to do something which is impossible. With the current rule, the recipient is restricted from claiming Input Tax Credit because of the failure of the supplier in furnishing details in Form GSTR-1 on time.
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Department of Correction
Murder Suspect Accidentally Released From Jail, NYPD Says
Christopher Buggs had been in custody for three years awaiting trial for a 2018 Brooklyn murder
Published March 10, 2021 • Updated on March 11, 2021 at 12:07 am
The New York City Department of Correction appears to have accidentally released a murder suspect awaiting trial, and the NYPD says they're actively searching for him.
Christopher Buggs, 26, was arrested in Feb. 2018 on charges of second-degree murder. Authorities alleged he was responsible for the death of Ernest Brownlee, 55, who was shot in front of a Throop Avenue deli in Bed-Stuy.
Buggs sat in custody for three years, until he was "inadvertently released" due to a clerical error on Monday, police said. Court records indicate he was next due for a hearing in June on the murder charges.
Department of Correction online inmate records also show Buggs' status as "Released." He had been held in the Otis Bantum facility on Rikers Island. It appeared Buggs was released on an unrelated contempt of court finding, with Rikers staff not realizing he should still be locked up for his alleged role in the murder case.
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"We are aware of this incident and a full investigation into how this happened is underway. Right now we are working with our law enforcement partners to return this individual to custody," Peter Thorne, the department's deputy commissioner of public information, said in a statement.
New York City Mayor Bill de Blasio weighed in on the apparent mistake as well, saying that the city is looking to put "additional safeguards in place to make sure this never happens again. That's very frustrating." The mayor said he's confident Buggs will be re-apprehended soon.
"If he's out, ain't no telling where he is at or what is on his mind," said Isaac Mickens, a friend and advocate for the widow of Brownlee. "As of right now, it is more or less like a cat and mouse game. We're just waiting. I am waiting for them to catch the man."
Buggs' mugshot shows him with a scar on his face and a dollar sign tattoo on his neck.
Copyright NBC New York
Department of CorrectionBrooklyn


The University of Arkansas Community Design Center led an interdisciplinary team whose project, Fayetteville 2030: Food City Scenario, speculates on what Fayetteville would look like if its growth integrated local urban food production substantial enough to create self-sufficiency.
The project was one of 10 entries, out of more than 150 submitted, recognized in the 61st Progressive Architecture Awards program, a highly coveted industry program that honors trending work by North American architecture and urban design practices. It received an Honorable Mention award for its potential and holistic approach to design. The awards were announced Feb. 20 at a gala in New York, and will be featured in the March issue of Architect magazine, the official magazine of the American Institute of Architects.
Fayetteville currently has a population of 75,000, which is expected to double over the next 20 years. Although the region is the most prosperous in the state, it also has one of the state's highest child hunger rates.
This scenario devises a middle-scale urban food production model between the scale of the industrial farm and the individual garden. This "missing middle" foodshed functions as an ecological municipal utility, featuring green infrastructure; public growscapes, such as edible forest farms, orchard-lined streets, fruit and nut boulevards; food hubs; organic waste recycling districts; and various other agrarian initiatives.
Food City Scenario devises a new planning tool that outlines an ecology of five urban growing guilds. Each guild is associated with a niche function like pollution remediation, through low-impact storm water management landscapes and carbon sinks that support safe growing, as well as waste-to-energy districts for recycling of waste streams toward effective nutrient management and rebuilding of healthy soils. Incorporating agriculture back into the city environment will benefit economic development, add value to food products, provide community-wide ecosystem enhancement, and promote healthy lifestyles by expanding access to nutritious foods, Luoni said.
The interdisciplinary team at the University of Arkansas worked with local nonprofit groups dedicated to fighting hunger and poverty. This collaborative plan involved the Fay Jones School of Architecture, the department of biological and agricultural engineering, the Center for Agricultural and Rural Sustainability, the School of Law and its master of laws program in agricultural and food law, the department of food science, and the city of Fayetteville.
Marty Matlock, professor of biological and agricultural engineering in the College of Engineering, and executive director for the University of Arkansas office for sustainability, led a class that worked with the Community Design Center's team to evaluate soil, climate, and topography characteristics for this project.
"We were proud to contribute to Food City Scenario and impressed with the innovation and creativity that the Community Design Center brought to the task," said Susan Schneider, director of the master of laws program in agricultural and food law and professor in the School of Law. "Interdisciplinary projects like this enhance our work and remind us of the need to work together as a community to solve urban and food system problems." Schneider is also the co-author of a forthcoming book on urban agriculture that includes a section on Food City.
The Community Design Center was founded in 1995 as part of the Fay Jones School of Architecture. The center advances creative development in Arkansas through education, research and design solutions that enhance the physical environment. It has provided design and planning services to more than 45 communities and organizations across Arkansas, helping them to secure nearly $65 million in grant funding to enact suggested improvements. In addition to revitalizing historic downtowns, the center addresses new challenges in affordable housing, urban sprawl, environmental planning, and management of regional growth or decline. The center's professional staff members are nationally recognized for their expertise in urban and public-interest design, and their work has received more than 90 design awards.


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Reza Madadi's last win was in April of 2013 heading into his matchup with Yan Cabral in May. At 37 year olds the Allstars Training Center fighter was coming off a loss and trying to become the oldest fighter to ever win a lightweight bout in the UFC. Overcoming all the odds against him, Mad Dog's comeback stoppage TKO in the third round at UFC Fight Night 87 gives him mmaViking.com's Nordic 2016 Comeback Fighter of the Year.
After spending 14 months of his life in prison, Madadi was fortunate to be signed back to the leading organization and the Stockholm based fighter was lucky not to be cut by the UFC after losing to Northern Irishman Norman Park in his one bout of 2015. The Dublin loss was a big setback for Madadi that was looking to make a statement that he was just as good as the fighter that once beat highly ranked American Michael Johnson.
Cobral started out strong early in his battle with the wrestler, and took the first round by securing a take-down late in the round. The Brazilian was a bigger fighter, dropping from welterweight, but Mad Dog grinded his way back into the bout and started to wear down the Brazilian late.
Both fighters were slowed by the 10 minutes of battle coming out to the third round but Madadi landed a huge uppercut when he needed it. The big punch lead to several unanswered shots and a finish over a dazed Yan Cabral at Ahoy Rotterdam, reviving Madadi's career and finally returning to the win column.


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Главная » Horoscope » Compatibility of the Dragon and the Bull
Compatibility of the Dragon and the Bull
Compatibility of the Dragon and the Bull — a relationship without a chance
Compatibility of the Dragon and the Bull — what is it? How partners are able to get along with each other and build harmonious relationships?
Astrologers do not give an unambiguous forecast, so we will try to understand all the nuances in more detail.
General Compatibility Characteristic
Dragon and Bull are representatives of two very strong energetic signs. Their union is amazing, because, united, they create not just a pair, but a spiritual tandem.
But both do not always understand what responsibility fate has placed on them.
What characterizes the relationship between the Bull and the Dragon:
This union is one of the most ambiguous in the eastern horoscope. Partners have extremely inconsistent characters, so to exist together and build harmonious relationships for them in practice is quite difficult. But they must learn to comfortably interact, develop together and benefit society — this is their karmic task.
The bull is conservative by nature. He was used to certain rituals, setting, environment. It is not adjusted to change anything, because in a new situation it feels not so comfortable.
The dragon, on the other hand, is open to adventure and novelty. He has tremendous willpower, he is generous and generous, but sometimes unbearable in his stubbornness. It can be hot-tempered and unrestrained in words.
Dragon nature of fire. It ignites quickly, but no less quickly goes out. A bull should help a partner catch a wave of energy and manage to do all important things in a short period of inspiration. Otherwise, it will be difficult for him to live.
Generally surprising that made them pay attention to each other. The bull avoids such people, and at first the chosen one seems dramatically dull to the Dragon.
The only thing that unites partners is love for nature.
Bull Man and Dragon Woman
In this version of the union compatibility can not be called favorable. This is a pair of two stubborn people who will never yield to each other.
It is strange that relations between them have arisen at all, because they are full of contradictions, claims to the outside world and to each other.
What features can be noted in such a complex pair:
A man attracts the chosen one with his strong character. He is purposeful, and not only in words, but also in deeds. Set clear goals and a coherent plan of action, which is followed, not paying attention to external obstacles. In addition, he is focused on serious relationships, wants families and children, is faithful and will never change.
The man in this pair is just made for marriage, but the same cannot be said about the woman. She is like a cat that walks by itself, a man of freedom. She values her independence above all else, is not ready to limit herself to anything, serious relations are not for her at all.
She loves gloss and appearance shine, prefers to appear rather than be. She tries with all her might to impress others, to remain in the center of attention. He does not want to hear anything about responsibility, life and other mundane things. If at first a man is amused by such a character, he gradually begins to irritate, then derange himself, but in the end he realizes that he has chosen the wrong person and decides to end everything with a break.
Most often, such a union — no more than a light holiday romance. Although the relationship can last longer, provided that the girl has walked enough, and the man gained experience and wisdom to put up with the shortcomings of the second half.
But to get married and live together until old age, they can only if everyone tries to remake themselves a little. The girl will settle down, the man will get rid of a bit of tediousness.
Watch the video on:
Dragon Man and Bull Woman
This is a very unstable relationship that is unlikely to last long. For a serious and thorough girl, the Dragon will seem too frivolous, empty, unreal.
She will take it as an exciting adventure, but is unlikely to agree to a serious relationship.
What can be noted in such a union:
The dragon is quite satisfied that no matrimonial plans are being made in relation to him. He fits the role of a lover or a passing cavalier. He is not going to bind himself at all by marriage, he cannot stand obligations. Therefore, if both are satisfied with this situation, they can enjoy a magnificent short novel for a while.
A man charms the chosen one with his irrepressible energy, bright charisma and sparkling humor. At first, he seemed to her an incredible enthusiast, a creative person, almost a genius. But rose-colored glasses will quickly fall down, and she will understand that the chosen one speaks more than she does.
He too quickly disappointed in his beloved. When the passion passes and the romantic fervor fades away, it will seem to him incredibly boring, gray, while it demands only bright colors from life. Quiet and peaceful relationships will come to naught to a general satisfaction.
And the novel begins, as a rule, at the moment when the Dragon, a little tired of the endless series of entertainments, begins to seek peace and solitude.
A disaster if they decide to start a family. A man will rarely appear at home, and his wife will izvestret himself with jealousy and turn into a grumpy woman, with whom it is unpleasant to be in the same territory.
In the rare moments of fatigue and the desire to retire, the Dragon will be at home, interacting with children and listening to the claims of the second half. But after a week, maximum = a couple of months, he will again sail away «into the sunset.»
A rare woman will endure such an attitude, so the Bull remains with him only when she has victim syndrome or incredible patience.
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Castelfalfi ist ein italienisches Dorf (Fraktion, italienisch frazione), das  zur Gemeinde Montaione in der Metropolitanstadt Florenz gehört.

Geschichte

Namensgeschichte
Castelfalfi ist ein mittelalterliches Dorf (Borgo). Aus einem Schriftstück aus dem Jahre 754 geht hervor, dass der ursprüngliche Name Castellum Faolfi oder Farolfi langobardischen Ursprungs ist.

Frühgeschichte
Erste Siedler waren – soweit nachweisbar – die Etrusker, die vor rund 2500 Jahren auch die Gegend um Castelfalfi bewohnten.

Aus der Römerzeit und dem frühen Mittelalter ist nur wenig über Castelfalfi bekannt. Historiker sind sich jedoch einig, dass die Gegend nur sehr dünn besiedelt war. Die "Barbaren" scheinen die einzigen gewesen zu sein, die in diesem Landstrich siedelten. Später ließ sich der Langobarde Walfredo, Sohn von Ratgauso und Stammvater des Adelsgeschlecht Della Gherardesca, hier nieder, als er das Dorf von der Abtei Monteverdi geschenkt bekam. 1139 verkaufte sein Nachfahre Ranieri Della Gherardesca seinen Anteil am Castello für 100 Lire an den Bischof von Volterra.

13. bis 15. Jahrhundert
Florenz gewann immer mehr an Einfluss. Im Jahr 1230 wurden Castelfalfi und die umliegenden Dörfer San Miniato unterstellt, das seinerseits unter florentinischer Vorherrschaft stand. Auch wenn ansässige Adelsfamilien gegen diese Vorherrschaft rebellierten, blühte Castelfalfi unter florentinischer Herrschaft auf. Die aufsässigen Familien wurden abgestraft und Teile des Borgo beschlagnahmt. 1370 wurde Castelfalfi direkt Florenz unterstellt. Eine bekannte Persönlichkeit aus dieser Zeit ist Bertino da Castelfalfi. Der großherzige Landwirt half den Armen im Krieg zwischen Florenz und dem Grafen von Virtú.

16. bis 18. Jahrhundert
Im Krieg zwischen Florenz und Siena im Jahre 1554 wurde Castelfalfi geplündert und größtenteils zerstört. Mit dem darauffolgenden Wiederaufbau gingen weite Teile des Dorfes in den Besitz der Familie Biondi über, die die Dorfsanierung finanzierte. Nach der Landreform des Großherzogs von Florenz im Jahre 1774 wurde Castelfalfi wieder zu einer Gemeinde unter der Verwaltung Montaiones vereint. In dieser Blütezeit stieg die Einwohnerzahl auf 476 Einwohner an. Da die Familie Biondi die reichste Familie des Landguts war, ging der Besitz und die Verwaltung Castelfalfis an sie über.

Die große Landflucht im 20. Jahrhundert
Anfang des 20. Jahrhunderts wurde im Borgo eine Tabakfabrik errichtet und im Zusammenhang damit wurden auch die Straßen um das Dorf ausgebaut. Die Nachkriegszeit brachte nach langen Jahren der Entbehrung in den 1950er Jahren endlich den wirtschaftlichen Aufschwung nach Italien. Allerdings führten diese Entwicklungen in so abgelegenen Dörfern wie Castelfalfi zu Abwanderungen in die aufstrebenden Industriezonen im Norden Italiens. Die 1950er und 60er Jahre waren hauptsächlich bestimmt von Landflucht. Castelfalfi wurde nahezu vollständig entvölkert.

Die verlassene Ortschaft inmitten der weiten Hügel der Toskana war 2002 Schauplatz der Pinocchio-Verfilmung Roberto Benignis.

Rückgewinnung des Dorfes
Nach der jahrzehntelangen Verwaltung durch die Familie Biondi wurde Castelfalfi 1965 von der Tuchhändlerfamilie Benelli aus Prato gekauft. Nachdem diese bankrottgingen, verkauften sie 1980 Castelfalfi an Mailänder Unternehmer. Nach dreijährigen Verhandlungen mit den toskanischen Behörden bekamen sie die Erlaubnis für ein ambitioniertes Projekt, das die Landwirtschaft in dieser Gegend revitalisieren und den Tourismus fördern sollte. Die Hälfte der bestehenden Häuser wurde zu Touristenappartements umgebaut. Es entstanden ein Restaurant im Castello, ein Schwimmbad, ein 18-Loch-Golfplatz und Tennisplätze. Wegen fehlender finanzieller Mittel wurde die Restrukturierung nur halb realisiert. Das Geldinstitut, das das Bauvorhaben finanzierte, musste Konkurs anmelden.
Nach dem Scheitern des ambitionierten Projekts wurde Castelfalfi wieder Eigentum der Gemeinde, die es kurz danach zum Verkauf freigab. Es gab viele Interessenten – darunter auch Silvio Berlusconi und Sarah Ferguson, ohne dass es zunächst zu einem Vertragsabschluss kam.

Nachdem das Dorf nur noch zirka fünf Einwohner hatte, erwarb es die TUI AG 2007, um es zum größten Tourismusprojekt Italiens zu machen. Es sollte dort unter dem Namen Tenuta di Castelfalfi eine luxuriöse Dorfanlage entstehen, bei Erhaltung der historischen Bausubstanz. 2013 sollte das Projekt, in das bis dahin etwa 160 Millionen Euro investiert wurden, abgeschlossen sein. Die Vermarktung lief aber nicht wie geplant, so dass das Projekt zunächst zeitlich gestreckt wurde, und sollte nach Plänen im Jahre 2018 fertiggestellt sein. Im Jahre 2017 wurde das Fünf-Sterne-Hotel Il Castelfalfi – TUI Blue Selection eröffnet.

Im Mai 2021 wurde das gesamte Toskana-Dorf von TUI wegen finanzieller Probleme aufgrund der Corona-Pandemie laut FAZ "an einen niederländischen Käufer aus dem Imperium einer indischen Unternehmerfamilie" verkauft.

Sehenswürdigkeiten

 San Floriano, um das Jahr 1000 entstandene Kirche. Wurde 1511 neu errichtet und hatte von 1845 bis 1920 eine Loggia vor der Fassade. Die Kirche wurde 1920 und 2014 renoviert.
 In den 1970er Jahren wurde auf einem Landgut das Skelett eines Wals ausgegraben, dessen Alter auf 3,5 Millionen Jahre geschätzt wird. Es ist im Museo Comunale di Montaione ausgestellt.

Literatur
 Emanuele Repetti: CASTEL FALFI (Castrum Faolfi) in Val d'Era. In Dizionario Geografico Fisico Storico della Toscana (1833–1846), Onlineausgabe der Universität Siena (pdf, ital.)

Weblinks

 Offizielle Seite des Toscana Resort Castelfalfi
 TUI baut Feriendorf für Reiche. In: Der Spiegel, 7. Juni 2011
 Appell der Legambiente Toscana für den Schutz von Castelfalfi

Einzelnachweise

Ort in der Toskana
Fraktion in der Toskana
Montaione

redpajama_set_name: RedPajamaWikipedia


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Discussion in 'Modding and Customization' started by zeromaveric, Jan 24, 2019.
I have an idea in mind i'd like to do with my laptop. I've seen a few desktop videos of people adding LED strips wired to the motherboard, and my project is similar.


So, You Think You Have Food Allergies?
Is It Time to Talk to Your Doctor About Colorectal Cancer?
BPH: What is it, how is it treated?
Health and heritage: too tough to see a doctor?
Celery Juice: Health or Hoax?
Is this hot, new trend healthy or a hoax?
¿Alguien en tu familia es melindroso con la comida? Las botanas en forma de caracol te rescatarán.
How can a sibling rivalry be a good thing?
What are other types of dementia?
Urgent care, emergency room or doctor's office?
¿Cuándo debe visitar mi hija al ginecólogo?
Occasionally, a doctor may recommend using a neti pot to help with allergies, sinus infections or congestion. A neti pot is a small tea-pot shaped vessel you can use to pour liquid in one nostril and out of the other. However, you need to be careful with how you use it, or, more specifically, what you put in it.
A December 2018 article in USA Today discusses the case of a 69-year-old woman who died after getting infected with a brain-eating parasite following a year of use with a neti pot. The problem wasn't that she used a neti pot, however. It was the tap water.
The Centers for Disease Control and Prevention notes untreated tap water is not safe to use because it can contain parasites, such as Naegleria fowleri, the brain-eating amoeba. So, you may be thinking, if it's not safe for use in neti pots, does that mean it's not safe to drink? Not to worry, even if one of these nasty parasites is in a big sip of water, they won't survive stomach acids.
If a doctor recommends using a neti pot, follow the directions closely to make sure you stay safe. Remember, the CDC recommends using water that has been boiled for 1 minute (3 minutes at elevations above 6,500 feet) and cooled, or using distilled or sterile water.
Why is it so important to use properly treated water? Because amoebas like Naegleria fowleri could enter the body and lead to a disease known as primary amebic meningoencephalitis or PAM.
While infections from Naegleria fowleri are rare, when they do occur, they are usually fatal. In fact, the CDC notes only 4 known people have survived from the infection of the 143 infected between 1962 and 2017. It's a fatality rate of 97%.
Infections from the amoeba tend to happen in the summer months—July, August and September. The CDC says this is because the amoeba grows better in warmer water.
If your doctor recommends a neti pot, talk with them about safely using it and ensure you take the necessary precautions with the water that you use.
Want to see an allergist? Find one near you.
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This blog is provided for general information only. It is not intended to be—or to be construed as—medical advice, diagnosis, or treatment and is not a substitute for consultations with qualified health professionals who are familiar with your individual medical needs.


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text:
e-Newsletter: March 2022
Student Scholarships: Applications Due March 11
Each year the IEEE Vancouver Section awards
several student scholarships. This year marks the introduction of the fourth award in honour of John S. MacDonald, bringing the total available awards to $6,000. The Vancouver Section of the IEEE will award up to four $1,500 scholarships to students who best meet the objectives of the Scholarship Awards in 2022.
The award competition is open to undergraduate and graduate IEEE student members within the Vancouver Section's geographic area (province of BC, excluding Vancouver Island). The deadline for sending the application has been
extended by one week to Friday, March 11th 2022 at 11:59 pm. For more information, including award objectives and instructions on how to apply, please review the
Invitation for Student Scholarship Applications
Digital Skills & Readiness 101: The Skills YOU Need NOW to Prepare for the Future of Work
Dr. Melissa Sassi, IBM
Organizer: Young Professionals and Joint Computing Chapter
Thursday, March 10th, 12:00 noon to 1:30 pm. Online
As IBM Z's Chief Penguin, Dr. Melissa Sassi created her own IBM job title, job description, and is the Founder & Global Head of IBM Hyper Protect Accelerator, an IBM program focused on empowering early-stage startups to build and scale via business and technical enablement. Dr. Sassi has 100 startups in her existing portfolio with 40% early-stage fintechs.
Read more and register…
Vancouver Section AGM March 30th
The 2022 Annual General Meeting (AGM) of the IEEE Vancouver Section will be held online on the evening of Wednesday March 30, beginning at 7:00 PM. The meeting will cover several business items such as the auditor's report, and the announcement of section scholarship award recipients.
Due to current COVID concerns and limitations, the AGM will be held online once again. Though we will not be able to enjoy a full in-person "gala" event, we are planning an interesting and interactive event for our members and friends – an outstanding keynote speaker and the opportunity to network with your friends and colleagues!
This is a regular publication of the IEEE Vancouver Section.
Dr Chris Scholefield
IEEE Vancouver Section, All rights reserved.
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Mr. Aqua's Water Plant Soil is composed using specific proprietary blends of organic and inert ingredients providing all essential elements as well as a stable and ideal rooting media. The soil will also provide buffering capacities for softening water as well as a buffering pH from 6.6 – 6.8 depending on water parameters. The soil is a long lasting fertilized plant substrate lasting up to 12-18 months. It purifies water that is stained from driftwood. It prolongs water exchange periods up with its porous granular structure that is easily penetrated by plant roots.
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text:
Season starts next week
Yee Chun Leong
THE wait is finally over as Brunei's top tier football competition, the DST Super League, will kick off next Wednesday.
This was confirmed by National Football Association of Brunei Darussalam (NFABD) Chairman Competition Committee Hj Mohd Noor Hj Hamid yesterday when contacted by The Brunei Times.
Newly promoted IKLS, who finished runners-up in the DST Premier League last season, will battle it out against the Royal Brunei Police Force Sports Council (MS PDB) in the opener at the Balapan Track and Field of the Hassanal Bolkiah National Sports Complex in Berakas.
Najip FC will take on Kilanas FC in the second match at the Tutong Sports Complex two days later.
All eyes will be on the clash of the titans on April 5 with two-time defending champions Indera SC up against two-time runners-up Royal Brunei Armed Forces Sports Council (MS ABDB) at the Hassanal Bolkiah National Stadium in Berakas.
Kick off for all three matches will be at 8.15pm. The other returning teams for the DST Super League are Wijaya FC and Jerudong FC.
DST Premier League champions Lun Bawang are the other promoted side while Tabuan Muda (the national Under-23 football team) are set to make their debut completing the 10-team competition.
Indera finished last season's nine-team DST Super League with 43 points ahead of MS ABDB, who had 37 points.
The former won 14 games, lost one and drew one.
They scored a total of 51 goals and only conceded 14 throughout the campaign.
The DST Super League was initially slated to begin in February after the national football season started on Jan 24 with the 2015 Sumbangsih Cup, which Indera clinched after a 2-0 win over MS ABDB at the Hassanal Bolkiah National Stadium.
However, it was postponed due to the national team's participation in the 2018 World Cup qualifiers.
The Brunei Times
Labels: DST-National football League
Brunei U-23 team go down fighting
DPMM FC find Sergio to replace injured Fagan
Fagan out for six months
Under-23s off to Indonesia
Coaches agree that Brunei need more international ...
World Cup dreams over
Biggest game of my life'
Brunei make history
YouTube : Chinese Taipei 0-1 Brunei . 2018 FIFA Wo...
Brunei name World Cup Qualifiers players
Hat-trick hero Ramazotti stars in DPMM FC debut


text:
LITERARY POSEURS
Sir Bob Jones · May 18, 2020 · Uncategorized · 14 Comments
Over the last two months those of us following the news on the array of international television channels, must have viewed literally hundreds of proclaimed health experts, mainly American. Nearly every one of them has been interviewed against the background of bookshelves.
Books are my main preoccupation. On average I've spent about 8 hours every day over the last half century reading.
I read everything and own over 20,000 books in my homes in three countries. I haunt second-hand bookshops, particularly in Britain where I regularly am.
How do I have the time? Easy. First, I don't own a time-wasting cell-phone. When driving I listen to talking books, mostly fiction. I watch little television other than the news and some sport.
I've been in a picture theatre twice in the last 50 years, and so it goes.
In short I know books and I can tell you this with some expertise. That is that at least half of the health experts pitching their lines re the virus on the news channels have pretend background libraries, which I can ascertain at a glance.
There are all sorts of give-aways such as uniformity in size and colour, books lying flat in piles on shelves (which no self-respecting book lover would do) and many other clues.
On that note here's an amusing tale, although it wasn't at the time.
In the late 1980s when running a public company I was back and forward regularly between Sydney and Wellington. Additionally, my wife and I were constantly travelling to America and Britain.
We had two young boys and because of our constant absences, two live-in nannies respectively in our Sydney and Wellington homes.
Once, my wife decided to make a solid base in Sydney for a year as the boys needed stability, both going to Possums Pre-school there, an amusing name which has stuck in my memory.
One day I zipped home to New Zealand for a meeting and arrived about 8pm. On arrival I shot into the library to do some work. Sitting there I was overcome with an eerie feeling. It's a big library in 3 sections and my desk is at one end. The other two sections I left in darkness. As said, I was imbued with a strange sense of something amiss, as if the room was haunted.
So I rose and turned all the lights on. Bloody hell! The bored half-witted Wellington nannie, with nothing to do, had decided to "help me out" by rearranging the library, specifically in book size and colour. It took over a year to put it all back together again.
Even worse, she'd scrubbed a cricket bat clean of writing she perceived as despoiling it. This had been given to me by Jeremy Coney after our victorious 1986 unbeaten test series in England and which Jeremy had all the players sign.
But back to the health "experts". I have not the slightest doubt that history will record they were all grossly over-stating the concern and were loving their place in the limelight, something hitherto they'd never experienced. The biggest give-away were the American ones "thank you for having me" absurdity at the end of the interviews.
But the economic and social calamity inflicted on the world is more a consequence of lightweight politicians who have failed to show proper judgement in their copy-cat approaches.
Warren Buffett, noted for his buy quality and hold it through thick and thin highly successful investment approach (something I'd worked out years ago), has been selling down wholesale. It's tough for him as he's dealing in hundreds of billions of dollars of investment assets, not easily disposed of quickly.
So why this change from a life-time's investment philosophy which has served him so well? To quote him; "We do not know what happens when you shut down a substantial portion of your society. In 2008 our economic train went off the tracks. But this time we pulled the train off and put it in a siding – and I don't know of a parallel".
To that I'd say, Buffett doesn't know of a parallel in history for the very good reason there isn't one. What has occurred is abysmal political "leadership" which will have devastating political, social and health consequences.
Alan May 18, 2020 at 11:37 am
your final sentence nailed it Bob. What we've seen in the ' budget' from ardern and robertson is a great big sticking plaster placed over a festering wound..they're hoping that speading billions ( of borrowed money) will soothe the 55% or so of poor saps who think-or thought a couple of weeks ago-that labour etc should be the next govt. I strongly suspect their estimation of 9.8% unemployed will be seriously incorrect. I also suspect that they will extend this bullshit ' wage subsidy' long enough so that recipients still won't be "unemployed"…until after the election. Thats why ardern is frantic not to have the election pushed back, however there surely needs to be a census of some sort before an election can be held? What about the electoral role, are they just going to wing it like they're winging everything else?
Ruth Moreau May 19, 2020 at 2:15 pm
Agree with every word. We ain't seen nothing yet. The proverbial will hit the fan when the wage subsidy stops that's why Comrade Ardern wants to extend it. The government's handing of this "pandemic" has been catastrophic. They have crippled the economy using a sledgehammer to kill a fly. The most galling aspect of this disaster is that it is man-made, as apposed to an Act of God. Billions of dollars created out of nothing and charged out at interest The Babylonian financial system is to be destroyed and billions of borrowed money could be the catalyst. Fasten your seat belts for the wildest ride in history.
Andrew Atkin May 18, 2020 at 1:44 pm
I hope you were kind to your nanny. Her intentions were good I'm sure.
markscreaminggoosearmstrong May 19, 2020 at 10:17 am
"The road to hell is paved … " as my Mother used to say. 🙂
Kimbo May 19, 2020 at 11:50 am
The way to hell (or to tailor it, Andrew Atkin, to your personal philosophy, "bad karma") is paved with good intentions!
I mean, the first NZ cricket team to win a test series in England?! Remember it like it was yesterday: Hadlee six wickets in the first innings and Martin Crowe a century and Bruce Edgar, playing his last series before retiring, an 83 in the first test (drawn) at Lords. Also Willie Watson's test debut as I seem to remember Ewen Chatfield had an injured hand; Paddles ten for the match and a swashbuckling 68 on his English home ground in the second test at Trent Bridge. But he wasn't the only contributor as the tail hung around in our first innings, including John Bracewell who got a ton, with most of his runs coming from the front-footed cross-bat swot to square leg that was his trademark. Derek Stirling also hit a few boundaries at the end. However, the under-rated performer was Evan Gray who occupied the crease for six hours scoring 50, shoring up an end while the lower-order stroke makers piled on the runs. Now that's a test innings, and we won by eight wickets I seem to recall; and then the draw in the rain-affected last test at the Oval, but not before John Wright got a century, and Ian Botham, coming back from suspension and early in his opening spell, got two quick wickets (Edgar and Jeff Crowe) to equal, then pass Dennis Lillee's test wicket record, prompting the incredulous line from Graham Gooch, "Beefy, who writes your scripts?!" And then when England batted Tony Blain on debut for New Zealand dropped at stratospheric-challenging skier off Botham as he bludgeoned his way in quick order to an unbeaten 60. It was that punishment that likely did it for Derek Stirling as a test bowler, as his confidence never recovered, which was a pity as he had promise. And I have a feeling David Gower or Graham Gooch (who got a ton at Lords in the first test) scored centuries in that England innings. But saved by rain did us just fine.
So, no, some things you don't forget. Or vandalise. Would rather have my kids raised by CYFS than retain a child minder that…incompetent. I mean, come on, you've got to get your priorities right! 😳😂
william witherow May 18, 2020 at 2:40 pm
So what is Buffet doing with the money?
Caleb Mitchell May 18, 2020 at 3:55 pm
To a fair extent sitting on it, and waiting…
Feeling cool 🙂
Yes the bookshelves seems to have been a common, even cursory, observation by many. Interesting to see you finally get around to mentioning it.
What a horrific anecdote.
Billy May 18, 2020 at 8:14 pm
Maybe the health expert had a nanny? Dealt to the library? Bloody goats! But less irritating than the sheep who notice nothing
Sane Minority May 19, 2020 at 12:58 pm
I too noticed the Nanny syndrome occurring. Especially in the academic set. Funniest has to be the one who had library book wall paper. Almost as if, look I'm and expert, I got books.
Adrian May 19, 2020 at 9:33 pm
I sit here pulling out the odd grey hair in my beard, admiring my brown leather shoes, wondering where my sunglasses are (until I realized I left them on my head) all the time while contemplating what has been written by you Sir Bob and your followers. I certainly haven't read all the posts, only a few, but I do recall a few pertinent points.
I recall you writing that Labour are going to lose the Election yet Jacinda is now the most popular political leader in a century. You also quoted a Wellington newspaper reporter saying that 400 restaurants were going to close. Neither of these two things will come to pass. In your above post, the reader could interpret from what you've written that Warren Buffet is selling off great chunks of various assets at wholesale prices. In fact he is only selling off airline stocks at wholesale prices, which is quite understandable and he also states, never bet against America.
I am a commercial property investor with a good portfolio size and hold you in the highest regard. The commercial property world would certainly be a poorer place without you in in so I thank you very much for all your contributions in the property arena over the years.
Max Erman May 20, 2020 at 2:34 pm
To the 'thanks for having me' point I recall you thanking the host at the end of your appearances on the beat goes on…
No doubt there is footage online somewhere.
Morto May 20, 2020 at 8:53 pm
The response to a virus which culls the old, fat and infirm at 1/2 the rate of the flu was never about Health and Saving lives. This whole shebang is about creating a wall of inflation to cover up the looting of the pension schemes world wide by wall street and Inept Governments over the last 30 years. Why else would the solution be to force every into a position where they have zero income for 8 weeks, and are then encouraged to do the 'decent thing' and keep their employee's jobs open to save the country. Then as a sop to the voter conjure up a few hundred zeros in the form of business loans and helicopter cash, and splash the cash on the populace. We all know what happened to the Romans when they clipped the denarius, John Law and the Mississippi bubble, the Weimar Germans tried to print their way to freedom, and Zim's super successful efforts at making everyone a gazillionaire. So offer them all loans at very low rates, to create the inflation needed to make that pesky unaccounted for state pension fund obligation be achievably met, but only because a loaf of bread now costs $1000 and therefore that $1.5mm obligation is now only $50k in present day dollars. Way more affordable. Those super convenient swaps from the FED are superhandy. Weren't they so nice to offer Granty them back in December/ January.
But who wins?
What happens when the generational interest rates go from the lowest ever to highest ever? I recall my parents mortgage rates hitting credit card levels at 20%. So what if we get back to half that bad with a $200B national debt? HTF can we service that baby? Will they take a national park or a hydrodam or a dero railroad? Perhaps they'll take the mineral rights from the Antarctic to cover it? Or maybe we'll just carry on being debt slaves.
TO LIGHTEN YOUR DAY
MINDLESS FASHION AND TRUMP


text:
What is So.cl? Microsoft's New Social Network Takes On the Social Media Giants
ByRashaad Mubarak
While the world was captivated by Facebook, Twitter, Instagram, Tumblr, Pinterest, a new social network hit the internet in 2012. Microsoft's So.cl provides an outlet for users to creatively share their stories on the internet, but it's up for debate if the site has what it takes to challenge the social media giants of the internet.
So.cl is an "experimental research project" developed by Microsoft's FUSE Labs. So.cl focuses on expression and originality by allowing users to share personal experiences and stories with collages of pictures and videos. The project incorporates three other features — Video Party, Picotale, and BLINK — that encourage frequent communication and social interaction. Besides social networking, So.cl operates as a search engine by using Bing to search for data through public API (application programming interface). This means users can find content So.cl considers relevant to their collages or entire profile; So.cl will also recommend interests or "collections." Microsoft asserts that So.cl is not a competitor in the social media industry, but a complementary website designed for users to express themselves and share their life stories. Although So.cl is a successful promoter of expression and originality, the site pales in comparison to other social networking sites in the popularity contest.
The more popular social networking sites rely on status updates, tweets, animations, or gifs while So.cl relies more on the user's life experiences and interests. The concept of a social networking diary or journal is admirable, but its status as an "experimental research project" hinders its popularity and success among social media users. In addition, So.cl requires more contribution and introspection which could discourage users. Thus, So.cl needs more time to equal the amount of popularity and users of other social networking sites.
Facebook, Twitter, Instagram, Tumblr, Pinterest and LinkedIn are picking up users at an unprecedented rate. The number of users for So.cl remains unconfirmed, which implies that its fan base pales in comparison to the other social networking services.
Statistics (Users)
Alexa Rank (Global Rank)
200 million (Visitors Worldwide)
1 (Part of Google)
So.cl
So.cl is relatively new and garners little recognition in the social media industry. The bulk of So.cl users are from India; their numbers surpass So.cl's users in the United States. In addition to these two countries, So.cl has amassed users in Peru, Bangladesh, Pakistan, France, Mexico, Mauritius, Turkey and the United Kingdom. It appears the world is either unaware of So.cl, or it is eclipsed by the more popular social networking sites.
FUSE Labs has modified So.cl by redesigning the site's user interface and adding an imaging app (BLINK) and a meme generator (Picotale). Attempting to increase So.cl's popularity, FUSE Labs also installed a meme generator that allows So.cl users to create phrases for a specific meme. This could attract more users to So.cl or have no effect at all, leaving So.cl's future with a question mark.
The more popular social networking sites have established their place on the Internet as the reigning champions of social media. Since So.cl arrived in 2012, it is extremely difficult for the site to gain the quick, massive momentum its counterparts enjoyed. Microsoft has developed an innovative, useful site for people to share their experiences and interests, but So.cl needs considerable time to attain the amount of users that Facebook, Twitter, Instagram, LinkedIn or Tumblr have. However, one thing is certain: So.cl will more than likely surpass Myspace.