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On Location: St. Cloud State at St. Thomas on October 3, 2021
Posted on October 5, 2021 Posted in CCHA, NCHC, On Location, St. Cloud State Huskies, St. Thomas Tommies
This is the first article in our new On Location series where we will live tweet a college game that we attend in person and then later post an article here on the site.
Teams: St. Cloud State Huskies at St. Thomas Tommies
Where: Xcel Energy Center in St. Paul, Minnesota
When: October 3, 2021 at 5:07 p.m.
Opening puck drop at the first St. Thomas home game on October 3, 2021.
This was the second game of a home-and-home series to begin the 2021-22 season for these two teams. St. Cloud State hosted the first game on Saturday night and showed the new Division I team why they are ranked #2/3 in the preseason polls. The Huskies impressively won 12-2. The same two teams met on Sunday evening on October 3, 2021, in St. Paul. It's credited as the first Division I home game for St. Thomas despite it being at the Xcel Energy Center instead of the team's St. Thomas Ice Arena. 4,261 fans were in attendance.
St. Cloud State jumped out to a 1-0 lead on a power play goal from Zach Okabe in the first period. Jami Krannila and Spencer Meier assisted on the play. Shots on goal in the first period were 12-4 in favor of the Huskies.
St. Cloud State celebrates a first period goal to put the Huskies up 1-0.
The Xcel Energy Center is home to the NCHC Frozen Faceoff. This weekend of hockey played every March includes the final four teams left in the conference tournament with the winner of the title game hoisting the Frozen Faceoff trophy and earning an automatic bid to the national tournament. The NCHC conference tournament took place in Grand Forks, North Dakota in 2021 but the Frozen Faceoff will return to St. Paul in 2022. This game against St. Thomas is the first time St. Cloud State has played at the Xcel Energy Center since March 23, 2019, when the Huskies lost 3-2 in 2OT to UMD in the 2019 NCHC Frozen Faceoff title game.
The Xcel Energy Center is home to the NCHC Frozen Faceoff.
In the second period, the Huskies scored again to make it 2-0 heading into the third period. This time the goal was from Micah Miller with the assist from Kevin Fitzgerald. The Tommies had several chances but came up short. Shots in the second frame were 7-6 in favor of St. Cloud State.
St. Thomas gets a shot off in the second period of the October 3, 2021 game against St. Cloud State.
There's an area in the Xcel Energy Center that is devoted to the Hobey Baker and Patty Kazmaier Memorial Awards. It includes a list of past winners, replica Hobey Baker Award, and jerseys of a handful of past recipients. There are also summaries of the awards and what they mean to the hockey community.
Wing of the Xcel Energy Center dedicated to Hobey Baker Award.
Jerseys of past Hobey Baker Award winners showcased at the Xcel Energy Center.
Wing of the Xcel Energy Center dedicated to Patty Kazmaier Memorial Award.
There was no scoring in the third period. St. Thomas pulled the goalie but no goals were scored for either team before time expired. St. Cloud State outshot the Tommies 29-14. David Hrenak recorded his first shutout of the season as the Huskies opened the season with two wins. The Tommies put up a good fight but are still looking for the program's first Division I win.
Final minutes of the St. Cloud State and St. Thomas game on October 3, 2021.
Featured Flashback: St. Thomas hockey in 1924
Posted on September 30, 2021 Posted in CCHA, St. Thomas Tommies
The St. Thomas Tommies will begin a new chapter this Saturday, October 2. When the puck drops in St. Cloud against the Huskies, St. Thomas will have officially made the jump to Division I. The Tommies will be the second team in as many years to join the ranks of the top men's division of college hockey. But unlike Long Island, who created a program from scratch prior to the 2020-21 season, St. Thomas has a long and storied history of hockey. This is a program that began play in 1920. Prior to this season, the Tommies had only been a part of one conference: Minnesota Intercollegiate Athletic Conference (MIAC). With a new division comes new scenery. The Tommies will immediately participate in the revamped CCHA. However, the team must first play the national runner-up and NCHC powerhouse, St. Cloud State to begin the season. The home-and-home series will occur on Saturday and Sunday with the Tommies first home game taking place at the Xcel Energy Center; home of the Minnesota Wild.
In the featured photo, the St. Thomas hockey team is shown participating in an intrasquad scrimmage in 1924. The location is presumably on campus. The Tommies went 8-2 during the 1923-24 season. The program holds the record for most wins among all Division III hockey schools. As the sixth Division I hockey program in Minnesota, the program will have its hands full on the ice in the CCHA as well as the recruitment trail. But if past accomplishments are any indication and early trends continue for this new-look program, Rico Blasi's team will not only fit right in, it will excel within the State of Hockey.
Photo Credit: Minnesota Historical Society.
Our main goal is to preserve the history of American college hockey while educating all who want to learn more about this sport. For a comprehensive history of this sport, visit the U.S. College Hockey History page.
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In this narrative, Billy Graham shares his personal experience of growing older and in almost every page of the book, you can see a man who is full of confidence in the Lord. Although he is not a perfect man but rather has his own struggles, yet as you read his narrative, you couldn't help but notice that his deep trust in God is really palpable.
In these chapters, he talks about how we should view material riches and money, and how we should view our lives with a sense of mission from God as well as retirement. In the chapter on work, he advises younger people not be slaved to work so much so that our entire self worth are wrapped up in our work.
Instead of one who is fear of death, as he nears his last lap of earthly life, again we can see a man who rather embraces death as his days are drawing nearer and nearer home.
Others brag, "We've been there and done that!" The truth is that we gain new experiences until we die."
In conclusion, this is truly truly a worth account to read, so much gem to pick.


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Siganus vulpinus
Family : Siganidae
Text © DrSc Giuliano Russini – Biologist Zoologist
English translation by Mario Beltramini
The unusual and colourful Foxface or Rabbitfish (Siganus vulpinus – Schlegel & Müller, 1845, known also as Lo vulpinus), in French, "Tête de renard", is a saltwater fish with a flamboyant livery. Once, this fish was afferent to the genus Lo, one of the shortest of the zoological systematics, composed by a very modest number of tropical species, why an ICZN taxonomical revisitation is underway. Nowadays, the genus Lo has been replaced with the genus Siganus, even if some authors, especially ichthyologists of Japanese school, keep it still in use. However il belongs to the class of the Osteoichthyes (Osteichthyes), subclass of Actinopterygians (Actinopterygii), the order of Perciforms (Perciformes), family Siganids (Siganidae) and genus Siganus or, rightly, Lo. Besides the genus Siganus , ex- Lo, the family of the Siganidae includes the genus Siganites. The total number of the species, considering both genera, is of about thirty. They are medium-sized fishes. The common name of "rabbitfish" comes from the particular shape and profile of the snout present in the Siganus vulpinus, as well as in the other members of such family, which reminds the snout of this pavid, double-toothed, lagomorph; as matter of fact, the line of the snout is uninterruptedly curved downwards.
Zoogeography
The Siganus vulpinus is diffused (like some of the other species of this family), in the waters of the Indian and Pacific Oceans, with a high density in the Indo-Pacific geographic zone. Some species of this family do live in the Red Sea.
Habitat-Ecology
This perciform, like its conspecifics and congeners, frequents mainly coastal waters, even if, not infrequently, it penetrates into the mouths of the rivers or into brackish waters; a couple of species live also in fresh waters. Their food consists essentially of reef small animals, algae and aquatic plants, which they manage to break thanks the sharp tooth. None of these species, therefore the foxface too, is sought for by the fishermen as food, because the fleshes do not have any value, on the contrary, some of these species are considered as poisonous. Contrariwise, they are fished for being sold as ornamental fishes.
During the eighties of the last century, the ichthyological biologists have done interesting observations on the phenomenon which is underway since the end of the XIX century, of the penetration of these fishes into the Mediterranean from the Red Sea; Since 1869, year of inauguration of the Suez Canal, a two species of these rabbitfishes, the Siganus rivulatus and the Siganus luridus, together with many other fishes of various families, have reached the "Mare Nostrum", through this access route, settling there permanently; an instance of alien colonization, defined as "Lessepsian migration", which is the entrance and the stabilization of animal and vegetal species from the Red Sea to the Mediterranean one, taking advantage of the Suez Canal.
The Siganus volpinus, not edible, has spines connected to venom glands © Giuseppe Mazza
Utilizing this canal, the siganids have therefore reached the Turkish waters after having coasting the Middle Eastern regions.
By the time of the Second World War, they have reached the Greek archipelagos and the Cyclades; though having settled since little time in these areas, they did not waste too much time to meet the local fishermen, with their poisonous stings. To know up to where they can go, along with other Red Sea fishes, westwards in the Mediterranean will be established with further observations.
Morpho-physiology
The Siganus vulpinus is a medium-sized fish, usually less than 25 cm; some species of this genus may, however, exceed the 40 cm. The ventral fins, internally as well as externally, have, in correspondence to each hard thorny ray, three soft radii; the dorsal fin is, on the contrary, equipped with thirteen rays and ten radii, the first ray of this fin may be stretched less than the others, and is placed much ahead at the level of the nape; moreover, it is endowed of a very sharp thorn. The anal fin is supported by seven rays and nine radii and the pectoral ones, finally, are rather rounded and are not much big. In addition to the supposed poisonousness of its flesh, the spines of the aforementioned fins may cause quite painful wounds, as along the spiny rays of the dorsal and the anal are located venomous glands capable to inject their secretion in the wounds done at the least contact.
The skeleton of the skull does not have particular characteristics; there is absence of somatic sexual dimorphism between the sexes. The livery is characterized by a very bright lemon yellow colour on the dorsal, ventral, caudal and anal fins; the caudal peduncle and the whole body, strongly compressed, flattened and tall, are of white colour. Black dots are present and they colour the dorsal part of the snout, from the head to the tip; also the throat and the cheeks are black coloured, and there is present a round dots of the same colour in the supero-posterior part of the back. The eyes are big and dark.
Ethology-Reproductive Biology
Not much is known about the life way and habits of the Siganus vulpinus, like for the other members of the family of the Siganidae, the same applies to their biological cycle. The data currently in possession of the ichthyological bologists tell us that this fish has a calm character, that he tends to continuously explore the reefs and the relevant coral ravines, looking for food particles. The social relations with the other members of the group where it is gregarious, become tense when is coupled for reproducing, otherwise, in other circumstances, it is fairly sociable. Temperatures between the 24-30 °C are needed for living well. In case of attack by a predator, like a moray eel, it pretends to be dead, loses all the colours becoming grey with some blackish dot, then lies on the bottom and breathes very slowly; doing so, the predator ceases the attack and after a few minutes all goes back to the normality.
It does not reproduce in aquarium, and there are no data about its reproduction in nature. The vulnerability index of this species is of 24 over 100.
Amphacanthus vulpinus Schlegel & Müller, 1845; Lo vulpinus Schlegel & Müller, 1845; Teuthis tubulosa Gronow, 1854; Teuthis vulpina Schlegel & Müller, 1845; Teuthis vulpinus Schlegel & Müller, 1845.
→ For general information about fishes please click here.
→ To appreciate the biodiversity within the Osteichthyes, the BONY FISH, and find other species, please click here.
Siganus vulpinus was last modified: November 27th, 2019 by Giuseppe Mazza

redpajama_set_name: RedPajamaCommonCrawl


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Doc Rivers: 'I'll Be Very Happy' When Kobe Bryant Retires
Mark D. Smith-USA TODAY Sports
Kobe Bryant, Chris Paul Talked About Winning Titles Before Vetoed Trade
Back in 2010, the Los Angeles Lakers were able to get some revenge against their arch rivals by beating the Boston Celtics in seven games in the NBA Finals. It was the second of back-to-back titles for the Lakers with Kobe Bryant winning his fifth and final championship ring.
The loss to the Lakers at the Staples Center back in 2010, and all the frustrating nights trying to figure out how to stop Kobe Bryant, has stayed with current Los Angeles Clippers head coach Doc Rivers to this day.
Apparently Bryant's retirement can't come soon enough for Rivers via Dan Woike of OC Register:
"I'll be very happy when Kobe retires. He's inflicted pain on me – personally." Doc Rivers
— Dan Woike (@DanWoikeSports) April 3, 2016
Two years prior to winning a title in 2010, the Lakers lost to the Celtics in the Finals in devastating fashion. Rivers' Celtics squad got the best of Los Angeles in six games with the final game being especially painful for Bryant as the Lakers suffered a 39-point blowout defeat.
Bryant used the loss to the fuel his fire to get back on top and was able to accomplish that feat. Kobe led the Lakers to three straight NBA Finals appearances and two titles while playing alongside Pau Gasol.
After Sunday's game against the Celtics, Bryant will have only six games left in his NBA career with two of those games coming against Rivers' Los Angeles Clippers. The Lakers will face the Clippers on back-to-back nights at the Staples Center with Bryant and company being the away team on Tuesday and the home team on Wednesday.
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{{Info/Futebol/seleção
|apelido     = Chollima|nome        = Coreia do Norte
|Bandeira    =
|associacao  = Associação de Futebol da RPDC
|confederacao= AFC (Ásia)
|material    =  Choeusu
|treinador   =  Yun Jong-su
|capitao     =  Ri Myong-guk
|maispart    = Ri Myong-guk (118)
|artilheiro  = Jong Il-gwan (26)
|codigofifa  = PRK
|rankingfifa = 86
|melhorcolfifa = 57 (Novembro de 1993)
|piorcolfifa = 181 (Outubro de 1996)
|rankingelo = 66
|melhorcolelo = 26 (Julho de 1966)
|piorcolelo = 87 (Julho de 2005)
|partint=  0 - 1 Coreia do Norte Beijing, 7 de outubro de 1956
|maiorvit=  Coreia do Norte 21 - 0 Guam Taipé, República da China; 11 de março de 2005
|maiorder=  Portugal 7 - 0 Coreia do Norte Cidade do Cabo, 21 de junho de 2010
|modelo=padrão
|skin1=_dpr1617h
|skin_be1=_dpr1617h
|skin_bd1=_dpr1617h
|skin_calção1=_dpr1617h
|braçoesquerdo1=FFFFFF
|corpo1=FFFFFF
|braçodireito1=FFFFFF
|calções1=FFFFFF
|meias1=FFFFFF
|skin2=_dpr1617a
|skin_be2=_dpr1617a
|skin_bd2=_dpr1617a
|skin_calção2=_dpr1617a
|braçoesquerdo2=FF0000
|corpo2=FF0000
|braçodireito2=FF0000
|calções2=FF0000
|meias2=FF0000
|medalhas         =

|Ri Myong-guk}}

A Seleção Norte-Coreana de Futebol representa a Coreia do Norte nas competições de futebol da FIFA. Filiou-se à FIFA em 1945.

 História

A primeira grande aparição da seleção Norte-Coreana em termos mundiais ocorreu justamente na primeira vez em que participaram de uma Copa do Mundo, na Copa do Mundo FIFA de 1966.
O time até então desconhecido e sem experiência internacional era cotado como um dos mais fracos do mundial; mas viriam a fazer história''.
Durante a fase de grupos da Copa do Mundo FIFA de 1966, a equipe eliminou surpreendentemente a seleção da Itália na última rodada, carimbando o acesso às quartas de final, onde jogou contra Portugal. Neste jogo, a Coreia do Norte estava vencendo por 3-0 e contava com o apoio dos fãs ingleses; mas Portugal protagonizou uma das maiores reviravoltas da história das copas do mundo, acabando por vencer por 5-3, com quatro gols de Eusébio.
Após o surpreendente desempenho na competição, os jogadores foram recebidos como heróis nacionais.

Partidas na Copa 1966:
  0 – 3
  1 – 1
  1 – 0

  3 – 5

Seu primeiro título foi a medalha de ouro nos Jogos Asiáticos de 1978 (dividido com a Coreia do Sul) e obteve uma medalha de prata nessa mesma competição em 1990. Também conquistou a medalha de ouro na Universíada de 1985.

Copa do Mundo de 2010

No dia 17 de junho de 2009 a seleção Norte-Coreana se classificou para a Copa do Mundo FIFA de 2010 na África do Sul após empatar sem gols com a seleção da Arábia Saudita.

Na Copa do Mundo FIFA de 2010, a seleção norte-coreana esteve no grupo G juntamente com Brasil, Portugal e Costa do Marfim.
A seleção não correspondeu às expectativas de obter um bom desempenho, assim como em 1966 e foi eliminada logo na primeira fase.
Uma das imagens mais marcantes da Copa ficou por conta do choro de Jong Tae-Se enquanto o hino nacional norte-coreano era executado.

Partidas na Copa 2010:
  1 – 2
  0 – 7
  0 – 3

Após a fracassada campanha, a rádio Ásia Livre e a imprensa sul-coreana noticiaram que o treinador e a equipe foram obrigados a subir em um palco no Palácio da Cultura Popular, diante de 400 funcionários públicos, estudantes e jornalistas, e teriam sido submetidos a seis horas de críticas e humilhações.
A FIFA, no entanto, negou as acusações depois de investigações.

Preparação para a Copa do Mundo de 2010

No final do segundo semestre de 2009, na preparação para a estreia da seleção contra o Brasil a equipe disputou um amistoso contra uma equipe da segunda divisão do campeonato paulista, o Atlético Sorocaba. Foi a primeira equipe sul-americana a participar de um jogo em solo norte-coreano, ainda mais contra a seleção nacional.

O jogo foi disputado no Kim Il Sung Stadium, na capital Pyongyang, sob a vista de vários membros da embaixada brasileira, e por cerca de oitenta mil torcedores, enquanto cerca de 40 mil outros ficaram do lado de fora assistindo por telões.

A partida foi bastante equilibrada, com as duas equipes tendo várias chances de abrir o placar, com o goleiro norte-coreano fazendo belas defesas durante o jogo, que terminaria mesmo num empate sem gols.

Elenco atual

Os 23 jogadores seguintes foram convocados para Copa do Leste Asiático em partida contra  Mongólia

 Atualizado até 28 de dezembro de 2019

Desempenho em competições

<div style="text-align:left">

Títulos
 Jogos Asiáticos: Medalha de ouro - 1978*
 Universíada: Medalha de ouro - 1985*'''dividido com a Coreia do Sul.

Campanhas de destaque
 Copa do Mundo: 8º lugar - 1966
 Jogos Asiáticos
 medalha de prata: 1990
 Universíada
 medalha de bronze: 1987

Uniformes

Uniformes atuais
 1º - Camisa vermelha, calção e meias vermelhas;
 2º - Camisa branca, calção e meias brancas.

Uniformes dos goleiros
 Camisa azul, calção e meias azuis;
 Camisa bege, calção e meias pretas.

Ver também
 Eliminatórias da Copa do Mundo de Futebol de 2010

Futebol da Coreia do Norte
Seleção Norte-Coreana de Futebol

redpajama_set_name: RedPajamaWikipedia


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Tekie Geek had an expo table at the event, provided free WiFi for guests, and President Geek Mike Bloomfield also offered a presentation. The presentation was titled "Introducing Today's Smart Home and Office." Mike spoke about some new products such as the Nest Line of Products, TiVO, Sonos, & Insteon. Tekie Geek also included information at their expo table about Home Theater Installation and their IT services.
The lead sponsors at the event included the Staten Island Advance, Barry's Auto Body, and Richmond County Savings Bank. The event provided free entry for all guests, Robot Wars that were created by high school students on Staten Island, vendor tables, and an array of new gadgets.


text:
our story our products our process our brands contact us
solutions to meet your every need
Our 40 years of experience have given us unique and unparalleled expertise when it comes to product development and sourcing. Our teams of over 400 specialists across 15 wholly owned offices around the globe, seamlessly deliver over 50 million products to satisfied customers each year thanks to our exclusive network and longstanding relationships with designers, craftsmen, manufacturers, quality assurance and logistical experts.
Contempo Chronology
Our story began in 1977, when Betty Wong, founded Contempo in Hong Kong. She started the company as a boutique sourcing house with a specialty in sweaters. As Contempo's founder, Betty established and maintained the company's standard of excellence for the next 40+ years!
Ahead of our time – Women were First!
Contempo was a pioneer in empowering and promoting women to business leadership roles. Betty identified talent and work ethic in her recruits. From the beginning, and as Contempo grew, she trained, nurtured and rewarded excellence with senior and executive positions throughout the company. Contempo remains an example of corporate equality and fairness…always valuing and promoting strong, talented women.
countries of origin serviced
pieces of cashmere products shipped over the last decade
percentage of female employees
connect with us globally
staff testimonials
Sammi Lee Merchandising, Taipei
"We wanted something extraordinary and unique for the opening of our new Taipei office. We decided to create a handspun installation with the most beautiful novelty yarns of the season. Despite our hectic schedule, everyone in the office pitched in for the entire month. Using 229 cones, weighing over 50 kilos, our wall of yarn was fabricated."
Winnie Kwok Merchandising, Hong Kong
"A small seal, crafted by an artist in Fujian, China, was designed to commemorate Contempo's 35th anniversary. The Chinese character "諾", or "vow", stands for our most treasured value – our commitment to honour promises to customers, vendors and colleagues."
Chris Tse CEO
"From humble beginnings, Contempo has grown into an international sourcing agent, attracting some of the finest industry talents, and servicing many top retailers in the market. But our path has never been a straight line. While there are times of smooth sailing, it is often through the unexpected twists and turns that we discover, learn, and gain new momentum. As we embark on our 40th anniversary and celebrate our achievements, we embrace our future with renewed optimism, enthusiasm and commitment."
Oreo Hong Kong
"I am the company dog and I come to work most Fridays. The best part of the workday is the food – pineapple buns, peanut butter toast, and the occasional roast pork with stir fried vegetable on rice – all treats from colleagues I have befriended over the years. I am a highly valued employee of the company. My proudest moment was to model for the company's product catalog – and to be chosen for the cover."
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"Designers always do more than just designing. One minute, we put on the hat of a supplier, discussing costing parameters, timelines for manufacturing, and product development. The next minute we become part of a sales team, working closely with buyers to develop ideas. We are a magician at times, coming up with instant solutions, and then a fortune teller, predicting the bestseller for the next season. It always seems impossible. Until it's done."
Kelly Shum Merchandising, Hong Kong
"I started my career with Contempo, in 1980. Our small office had fewer than 10 people when I first joined. Everyone was responsible for everything – following up orders, garment inspections, shipping, trips to the post office… we worked many 13-hour days. My parents thought I would quit within the first month, but this is my 37th year with Contempo!"
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Ideal as a gift of birth: Contains 1 pair of fabric shoes, a triangular cloth and a headband.
&. Sweet baby fabric shoes in blue and white striped pattern with pink seahorses.
&. For babies 1-6 months (foot length: 8-10 cm) or 7-12 months (foot length: 10-12 cm).
&. Easy cleaning at 30 °.


text:
St. Mark, Gonzales
On July 24, 1973, St. Mark Parish was created from the parish of St. Theresa in Gonzales. The founding pastor, Father Clarence Waguespack, soon took residence in a mobile home located close to newly-purchased church property. The parishioners worked enthusiastically to clear the wooded area of land assigned for the building of the new church. Father Waguespack celebrated Sunday Mass temporarily at the V.F.W. Hall and, for weekday Masses, a hall was built by the ushers and other parishioners.
Two years later, on December 7, 1975, the new church was dedicated and blessed by Bishop Joseph Sullivan and placed under the protection of St. Mark the Evangelist. The parishioners of St. Mark continued to enhance their church over the years. In 1978, stained glass windows representing church organizations were installed in the church, and a statue of St. Mark made out of Carrara marble was erected in front of the church. At the back of the church, a new sacristy was built which included a stained glass window commemorating the deceased members of the parish. Additionally, a beautiful shrine in honor of Our Lady of Lourdes was built near the PSR Building. The shrine is affectionately known as "The Grotto."
On July 24, 1983, St. Mark celebrated its 10th anniversary with a special event. On this day, the mortgage of all the debt of the parish was burned. Through the years, the parish has been blessed with nearly 50 organizations and ministries. The parishioners of St. Mark continue to pray, work and worship together as God's family in Gonzales.
Mass & Confessions
St. John-St. Theresa School
Rev. Rubin Reynolds
Pastor | St. Mark, Gonzales
rreynoldsdiobr.org


We don't believe in waiting for vacation time.
Nope. We believe in making every day more fun. Right here. Right now.
What's that? Too busy adulting? Then maybe you missed the memo: Grown-ups don't have to act like grown-ups ALL the time. Remember being a kid? Playing outside with our friends was our job. Turns out, we were straight-up smarty-pants. Play is serious! So even though our jobs are now our jobs, we still take play very seriously. Yup. Outside. With our friends.
But hold up. It gets better. Shenanigans, silliness, ridiculousness, laughter? Totally contagious.
Our super-fun, giant outdoor games and awesome knockdown tables (featuring fast, swearword-free assembly) are a great place to start. Or, the perfect way to up your game if you're already hip to this whole everyday-nonsense lifestyle.
Explore your own hometown. Find parks, festivals, concerts, tailgates, bars and restaurants with ultra-casual outdoor areas, or ask people over to play in your own backyard. Old friends, new friends, family, neighbors…heck, start a league! We love our hometown so much, we chose our name in honor of a local neighborhood full of green spaces to play and a fun-loving, young-at-heart, kind-to-the-Earth, let's-slow-down-and-enjoy-this attitude.
They say laughter is an instant vacation, so make time for play, and create fun right where you live. Embrace the chance to take yourself less seriously, add a few Belknap Hill games and tables, and see the possibility for fun in everything. Just like when you were a kid.
Now, go outside and play with your friends.


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Do squeaky brakes, a spongy brake pedal, or less stopping power have you searching for brake specialists near you in Garland? Firestone Complete Auto Care is the place to go when you need brakes for less than the other guys. And with our brake coupons, you can spend less on the brake repairs and services you need to keep you safe on the road. But how do you know when it's the right time to stop by? Watch out for signs! Smells, sounds, and sensations in your steering wheel can all mean you've got braking problems. Screeching noises can point towards worn brake pads and shoes. A burning smell near your tires isn't normal, and is a sign you need a brake inspection. No matter the trouble, your best bet is stop by for a free brake inspection. Otherwise, the damage could spread!
Visit your local Firestone Complete Auto Care for a free brake check in Garland, when it's most convenient for your schedule. During your inspection, our technicians will evaluate pad, rotor, and drum wear, on top of checking the health of your brake fluid and e-brake. We'll then discuss any services with you, like brake pad replacement, rotor and drum resurfacing, brake fluid change, or replacement of brake lines. Whether you need new pads or hoses, you'll find that we're one of the best choices for brakes on a budget. We perform nearly one million brake repairs every year!
Make sure that when you hit the brakes, you don't hit anything else. Conveniently book an appointment at Firestone Complete Auto Care for brake service in Garland at the first sign of squeaky brakes, low brake fluid, or a loss of stopping power. Most stores are open in the evenings and on weekends to better fit your schedule. Trust our work and trust your brakes. Find your nearest shop and invest in safe driving today!
From oil changes to alignments to engine repair, trust your nearest Firestone Complete Auto Care for your car or truck maintenance and repairs. We're your local car care center, tire store, and automotive shop combined into one. Our automotive technicians work hard to help keep your vehicle performing its best. When you need work done on your car or truck, we promise affordable prices and exceptional service. Ready to experience the difference? Book your Garland, Texas auto repair or service today.


Great 60x80 steel building located just off I35 on 4th Ave s in Clear Lake. Built with steel beams, heavy insulation, heated flooring, as well as a 23x64 mezzanine above the office space. This building is being sold with an additional 50x182 parcel located on the East side. Owner willing to sell separately. Current business also available to purchase separately. Call an agent today for more information.


I started this blog in 2013 but after 5 years I'm taking an open ended sabbatical sailing around the world on my own sailboat. I'm still doing some freelancing work for one small startup in silicon valley that allows me to pay my expenses, but I'm not actively looking for new clients. The work life balance I have with just one client is perfect for now.
A few weeks ago I published a post on how to write and translate for Mobile, where I explained the three Fs approach: Fast, Focus and Fun.
Some readers asked me how you can possibly be fun when you design something serious as say, a payment flow. Well, here's an excellent example from what I consider the best app out there in terms of sleek design and crisp content: Hotel Tonight.
Hotel Tonight is a San Francisco's startup founded in 2010 by Sam Shank, Jared Simon and Chris Bailey. It's in series D founding round, backed by VCs like, among others, Accel Partners. It's only on Mobile, their website is just a homepage where you can download the app.
If there's an app out there that abides by the three principles I've listed in my previous post, this is Hotel Tonight.
When I'm asked for examples of well designed apps with great content, tone of voice and style, Hotel Tonight is the first (and finest) example that comes to my mind. Oh, and one more thing! The app works really well and the deals are fantastic!
Please feel free to post other examples of apps with sleek design and great content!
1) Create a translation project importing a xlif and an MS Word file.
2) Create a new TM and import an existing one in both TMX and TXT format.
3) Create a new TD and import an existing one in TBX format.
5) Search a term in TD and TM.
6) Observe TM and TD results.
7) Run a concordance search.
9) Check numeral and tags consistency.
Unlike all other commercial tools available today on the market, Heartsome Translation Studio runs on a Mac! The User Interface is very sleek and the views can be customized according to your personal preferences. The translation happens in a grid, like in Trados, Déjà Vu or MemoQ. The segment's filter offers a good number of options and it can be customized. The toolbar is not too crowded with unnecessary options.
This tools work very well and are quite handy.
Practically your projects are saved in this default position: C:\Users\username\Heartsome Workspace\, where you have the folders Intermediate, Source, Target, XLIFF. I mean, is not as bad as Trados Studio, but there's got to be a more intuitive way to handle this. Another way to open a file for translation, is by dragging it directly into the Source folder under the specific project. I hope that someone is going to simplify this process.
Another annoying behavior is the Export feature. When you're done with your translation/review and you need to deliver the project back to the requester, you need to click on Project > Export Project and then select the path where you want to export a funky .hszip file, that is nothing more that a zip archive that needs to be renamed into .zip to be opened and that contains a Xliff folder with the .hsxliff file.
Overall, Heartsome Translation Studio is a very good tool that could potentially became an excellent one with some simple User Experience improvements. At the moment there's only one contributor on GitHub, but it's true that this tool become Open Source just a few months ago. The UI looks sleek and the tool is robust (never experienced a crash). It has lots of potential, and could easily take over Trados Studio if more developers start contributing. So watch out for Heartsome Translation Studio in the future!
In my next post I will be reviewing Omega T+. Stay tuned!
I took the time to compile an extensive list of CAT tools available on the market today, both commercial and Open Source. The goal is to compile a gap analysis and a comparison review.
I'd like to close 2014 writing about one of the hottest topics: language plural and gender rules. One of the issues I run more often into when I work on mobile apps is in fact the way developers handle plurals and genders. I've had the opportunity to raise this issue with many apps developers and designers lately, and I was surprised to learn that unfortunately very few of them are aware of the complexities of other languages and the way to tackle this kind of problem.
In my opinion, it is paramount for Mobile developer and designers to think ahead about their global audience and build these language plural rules in their apps since the very beginning. I've been insisting a lot on this, because internationalizing the strings of their apps retroactively is a lot more work than doing it incrementally throughout development. And more costly too.
Imagine your app suddenly becomes a hit oversea, for example in Russia. You need to localize it and you send your string files to the Localization team.
If you're Localization team is a good one, they will tell you that you can get away with that quick one/not one check when pluralizing nouns. These are the only two categories in English, but other languages aren't that simple. Your Russian users have 4 different rules for pluralizing their nouns! And if you think this is complicated, Arabic speakers have six!
If you want to learn more about plural rules, you can read the Unicode Common Locale Data Repository (CLDR) Project which provide tables and charts that can help developers to handle these cases. The category names (i.e. zero, one, two, few, many, and other) are common across all languages and the rules define the mapping between a quantity and the plural category to use.
other ⇒ No rule, or any other number.
In the past there wasn't any option for properly internationalizing your iOS app. The good news is that in mid 2013, Apple released Localizable.stringsdict that provides built-in support for plural and gender rules in the Foundation Release Notes for iOS 7 and OS X 10.9.
If you start to use these categories even before you need it, you will be able to reach a global audience faster than you would otherwise, saving yourself a lot of work, time and money!


Aside from capturing and digitizing original artwork, Bullivant Gallery also offers high level digital archiving and preservation of items such as valuable documents, maps, and heirlooms, both flat and dimensional. Our custom engineered copy stand system creates a 500 megabit ultra high resolution digital file of your original, which can then be used to create an archival-quality print with all the character of the original. Our equipment meets the stringent 4-star FADGI Guidelines (Federal Agencies Digitization Guidelines Initiative), the highest quality specification. This is the standard used by many federal institutions such as the Library of Congress.
One of the unique aspects of this system is that is completely portable, allowing us to scan your most valuable or sensitive items while working with your staff and archivist in the safety of your museum and gallery. Please inquire for more details.
Please click here to view some of our preservation projects.
Our custom designed and built copy stand features a 40″ x 60″ delicate items vacuum table, which gently holds the original art in place for the duration of the image capture. The lighting, camera, lenses, Phase One IQ4 150mega pixel digital back, and processing software are all optimized to create a digital capture with exquisite detail and superior color accuracy. Our state-of-the-art system is a hybrid of document capture solutions in use in the finest museums and archives in the world, truly, there is no higher quality image and document capture available.
Bullivant Gallery is a member of the Association of Midwest Museums and the Midwest Archives Conference, and subscribes to the standards for digital archiving as outlined by the FADGI guidelines.


text:
ICI, immune checkpoint inhibitor
Posted inTP Receptors
Posted by By kentlandsinitiative December 5, 2022
ICI, immune checkpoint inhibitor. Covariates Demographics, medical history and medications were obtained through Research Patient Data Registry (RPDR). performed to study the association between ICI use and pericardial disease as well as pericardial disease and mortality. An additional 6-week landmark analysis was performed to account for lead-time bias. Results There were 42 pericardial events in the patients treated with ICI (n=2842) over 193 days (IQR: 64C411), yielding an incidence rate of 1 1.57 events per 100 person-years. There was a more than fourfold increase in risk of pericarditis or a pericardial effusion among patients on an ICI compared with controls not treated with ICI after adjusting for potential confounders (HR 4.37, 95% CI 2.09 to 9.14, p 0.001). Patients who developed pericardial disease while on an ICI experienced a pattern for increased all-cause mortality compared with patients who did not develop a pericardial event (HR 1.53, 95%?CI 0.99 to 2.36, p=0.05). When comparing those who developed pericardial disease after ICI treatment with those who did not, a higher dose of corticosteroid pre-ICI ( 0.7?mg/kg prednisone) was associated with increased risk of pericardial disease (HR 2.56, 95%?CI 1.00 to 6.57, p=0.049). Conclusions ICI use was associated with an increased risk of development of pericardial disease among patients with malignancy and a pericardial event on an ICI was associated with a pattern towards increase in mortality. strong class="kwd-title" Keywords: immunotherapy Introduction Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that target and inhibit unfavorable immune regulators and thereby activate immune responses against tumor cells. The approved indications for ICIs are increasing rapidly, with ICIs currently indicated for the treatment of at least 16 malignancy types with over 100 ongoing trials.1 2 The use of ICIs may lead to toxicities involving a range of organ systems collectively described as immune-related adverse events (irAEs).3 The best described cardiovascular irAE is myocarditis, which may be fulminant and is frequently fatal.4C6 However, evolving data suggest that cardiac toxicities occur beyond myocarditis.7 These expanded toxicities include arrhythmias, heart failure, and atherosclerosis-related cardiovascular events.8C10 Among Rabbit Polyclonal to Cytochrome P450 26C1 patients with cancer, pericardial effusions often occur due to the cancer itself, but may also develop secondary to treatment with traditional cytotoxic chemotherapy, radiation therapy, or targeted therapies.11C14 You will find limited data around the occurrence of pericarditis or pericardial effusions among patients on an ICI. There have been case reports describing pericardial disease in patients treated with ICI.15 16 Additionally, in a study leveraging irAEs reported to the WHO VigiBase, pericardial disease, defined as pericarditis and pericardial effusions, represented 0.36% of all reported toxicities; this risk of pericardial disease was more than threefold higher with an ICI and was more common among patients with lung malignancy.17 While this methodologic approach benefits from the large sample size, interpretation is limited by the lack of a control group or descriptive demographics to allow for adjustment due to confounders. In this work, we aimed to add to the limited evidence base linking ICI therapy to pericardial disease. We were specifically interested in whether pericarditis or pericardial diseases DSP-0565 were increased among those on an ICI compared with controls and aimed to identify the risk factors for pericardial disease or pericarditis among those on an ICI. Methods Study design, establishing and populace This was a single-center, retrospective cohort study. A total of 2842 consecutive patients who have received treatment with ICIs from July 2010 to March 2019 at Massachusetts General Hospital, Boston, Massachusetts were included in the study. Study design is usually outlined in physique 1. Two analyses were performed to evaluate the association between ICI use with pericardial disease and to identify risk factors associated with disease incidence. To evaluate if the prices of pericardial disease (described, according to prior research, as pericarditis or pericardial effusion) had been improved with an ICI, we performed a cohort research comparing incidences having a cohort of 2699 control individuals with metastatic tumor who weren't treated with ICIs (style 1).8 Because of this approach, between January 1 we selected settings from all individuals treated for tumor at Massachusetts General Medical center, january 1 2008 and, 2012. There have been 9793 individuals who fulfilled this criterion; of these, 1250 individuals had been excluded as.We were specifically thinking about whether pericarditis or pericardial illnesses were increased among those with an ICI weighed against settings and aimed to recognize the risk elements for pericardial disease or pericarditis among those with an ICI. Methods Study design, population and setting This is a single-center, retrospective cohort study. the individuals treated with ICI (n=2842) over 193 times (IQR: 64C411), yielding an incidence price of just one 1.57 events per 100 person-years. There is a far more than fourfold upsurge in threat of pericarditis or a pericardial effusion among individuals with an ICI weighed against controls not really treated with ICI after modifying for potential confounders (HR 4.37, 95% CI 2.09 to 9.14, p 0.001). Individuals who created pericardial disease while on an ICI got a craze for improved all-cause mortality weighed against individuals who didn't create a pericardial event (HR 1.53, 95%?CI 0.99 to 2.36, p=0.05). When you compare those who created pericardial disease after ICI treatment with those that did not, an increased dosage of corticosteroid pre-ICI ( 0.7?mg/kg prednisone) was connected with increased threat of pericardial disease (HR 2.56, 95%?CI 1.00 to 6.57, p=0.049). Conclusions ICI make use of was connected with a greater risk of advancement of pericardial disease among individuals with tumor and a pericardial event with an ICI was connected with a craze towards upsurge in mortality. solid course="kwd-title" Keywords: immunotherapy Intro Defense checkpoint inhibitors (ICIs) are monoclonal antibodies that focus on and inhibit adverse immune system regulators and therefore activate immune reactions against tumor cells. The authorized signs for ICIs are raising quickly, with ICIs presently indicated for the treating at least 16 tumor types with over 100 ongoing tests.1 2 The usage of ICIs can lead to toxicities involving a variety of body organ systems collectively referred to as immune-related adverse occasions (irAEs).3 The very best described cardiovascular irAE is myocarditis, which might be fulminant and is generally fatal.4C6 However, evolving data claim that cardiac toxicities happen beyond myocarditis.7 These extended toxicities consist of arrhythmias, heart failing, and atherosclerosis-related cardiovascular events.8C10 Among patients with cancer, pericardial effusions often happen because of the cancer itself, but could also develop supplementary to treatment with traditional cytotoxic chemotherapy, radiation therapy, or targeted therapies.11C14 You can find limited data for the event of pericarditis or pericardial effusions among individuals with an ICI. There were case reports explaining pericardial disease in individuals treated DSP-0565 with ICI.15 16 Additionally, in a report leveraging irAEs reported towards the WHO VigiBase, pericardial disease, thought as pericarditis and pericardial effusions, displayed 0.36% of most reported toxicities; this threat of pericardial disease was a lot more than threefold larger with an ICI and was more prevalent among individuals with lung tumor.17 While this methodologic strategy benefits from the top test size, interpretation is bound by having less a control group or descriptive demographics to permit for adjustment because of confounders. With this function, we aimed to increase the limited proof foundation linking ICI therapy to pericardial disease. We had been specifically thinking about whether pericarditis or pericardial illnesses were improved among those with an ICI weighed against controls and targeted to identify the chance elements for pericardial disease or pericarditis among those with an ICI. Strategies Study design, placing and population This is a single-center, retrospective cohort research. A complete of 2842 consecutive individuals who have received treatment with ICIs from July 2010 to March 2019 at Massachusetts General Hospital, Boston, Massachusetts were included in the study. Study design is outlined in figure 1. Two analyses were performed to evaluate the association between ICI use with pericardial disease and to identify risk factors associated with disease incidence. To evaluate whether the rates of pericardial disease (defined, as per prior studies, as pericarditis or pericardial effusion) were increased with an ICI, we performed a cohort study comparing incidences with a cohort of 2699 control patients with metastatic cancer who were not treated with ICIs (design 1).8 For this approach, we selected controls from all patients treated for cancer at Massachusetts General Hospital between January 1, 2008 and January 1, 2012. There were 9793 patients who met this criterion; of those, 1250 patients were excluded as they received ICIs later in their treatment course. Of.To address a potential lead-time bias, we performed a landmark analysis including patients who were alive at six weeks. pericardial event, we compared patients who developed an event on an ICI with patients treated with an ICI who did not develop a pericardial event. Cox proportional-hazard model and logistical regression analysis were performed to study the association between ICI use and pericardial disease as well as pericardial disease and mortality. An additional 6-week landmark analysis was performed to account for lead-time bias. Results There were 42 pericardial events in the patients treated with ICI (n=2842) over 193 days (IQR: 64C411), yielding an incidence rate of 1 1.57 events per 100 person-years. There was a more than fourfold increase in risk of pericarditis or a pericardial effusion among patients on an ICI compared with controls not treated with ICI after adjusting for potential confounders (HR 4.37, 95% CI 2.09 to 9.14, p 0.001). Patients who developed pericardial disease while on an ICI had a trend for increased all-cause mortality compared with patients who did not develop a pericardial event (HR 1.53, 95%?CI 0.99 to 2.36, p=0.05). When comparing those who developed pericardial disease after ICI treatment with those who did not, a higher dose of corticosteroid pre-ICI ( 0.7?mg/kg prednisone) was associated with increased risk of pericardial disease (HR 2.56, 95%?CI 1.00 to 6.57, p=0.049). Conclusions ICI use was associated with an increased risk of development of pericardial disease among patients with cancer and a pericardial event on an ICI was associated with a trend towards increase in mortality. strong class="kwd-title" Keywords: immunotherapy Introduction Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that target and inhibit negative immune regulators and thereby activate immune responses against tumor cells. The approved indications for ICIs are increasing rapidly, with ICIs currently indicated for the treatment of at least 16 cancer types with over 100 ongoing trials.1 2 The use of ICIs may lead to toxicities involving a range of organ systems collectively described as immune-related adverse events (irAEs).3 The best described cardiovascular irAE is myocarditis, which may be fulminant and is frequently fatal.4C6 However, evolving data suggest that cardiac toxicities occur beyond myocarditis.7 These expanded toxicities include arrhythmias, heart failure, and atherosclerosis-related cardiovascular events.8C10 Among patients with cancer, pericardial effusions often occur due to the cancer itself, but may also develop secondary to treatment with traditional cytotoxic chemotherapy, radiation therapy, or targeted therapies.11C14 There are limited data on the occurrence of pericarditis or pericardial effusions among patients on an ICI. There have been case reports describing pericardial disease in patients treated with ICI.15 16 Additionally, in a study leveraging irAEs reported to the WHO VigiBase, pericardial disease, defined as pericarditis and pericardial effusions, represented 0.36% of all reported toxicities; this risk of pericardial disease was more than threefold higher with an ICI and was more common among patients with lung cancer.17 While this methodologic approach benefits from the large sample size, interpretation is limited by the lack of a control group or descriptive demographics to allow for adjustment due to confounders. In this work, we aimed to add to the limited evidence base linking ICI therapy to pericardial disease. We were specifically thinking about whether pericarditis or pericardial illnesses were elevated among those with an ICI weighed against controls and directed to identify the chance elements for pericardial disease or pericarditis among those with an ICI. Strategies Study design, setting up and population This is a single-center, retrospective cohort research. A complete of 2842 consecutive sufferers who've received treatment with ICIs from July 2010 to March 2019 at Massachusetts General Medical center, Boston, Massachusetts had been contained in the research. Study design is normally outlined in amount 1. Two analyses had been performed to judge the association between ICI make use of with pericardial disease also to recognize risk factors connected with disease occurrence. To evaluate if the prices of pericardial disease (described, according to prior research, as pericarditis or pericardial effusion) had been elevated with an ICI, we performed a cohort research comparing incidences using a cohort of 2699 control sufferers with metastatic cancers who weren't treated with ICIs (style 1).8 Because of this strategy, we selected handles from all sufferers treated for cancers at Massachusetts General Medical center between January 1, 2008 and January 1, 2012. There have been 9793 sufferers who fulfilled this criterion; of these, 1250 sufferers were excluded because they received ICIs afterwards within their treatment training course. Of the rest of the 8543 sufferers, we randomly chosen controls using a 1:1 proportion to match situations for age group and cancers type such as previous research using the same dataset.8 We further excluded sufferers without metastatic disease. In the next strategy,.LZ is supported by something special from Mr Gordan Dr and Pugh Christine Olsen. Contending interests: TGN is a consultant to and received costs from Intrinsic Imaging, H3-Biomedicine, Amgen, Roche, and AbbVie, beyond the current function. ICI with sufferers treated with an ICI who didn't create a pericardial event. Cox proportional-hazard model and logistical regression evaluation were performed to DSP-0565 review the association between ICI make use of and pericardial disease aswell as pericardial disease and mortality. Yet another 6-week landmark evaluation was performed to take into account lead-time bias. Outcomes There have been 42 pericardial occasions in the sufferers treated with ICI (n=2842) over 193 times (IQR: 64C411), yielding an occurrence rate of just one 1.57 events per 100 person-years. There is a far more than fourfold upsurge in threat of pericarditis or a pericardial effusion among sufferers with an ICI weighed against controls not really treated with ICI after changing for potential confounders (HR 4.37, 95% CI 2.09 to 9.14, p 0.001). Sufferers who created pericardial disease while on an ICI acquired a development for elevated all-cause mortality weighed against sufferers who didn't create a pericardial event (HR 1.53, 95%?CI 0.99 to 2.36, p=0.05). When you compare those who created pericardial disease after ICI treatment with those that did not, an increased dosage of corticosteroid pre-ICI ( 0.7?mg/kg prednisone) was connected with increased threat of pericardial disease (HR 2.56, 95%?CI 1.00 to 6.57, p=0.049). Conclusions ICI make use of was connected with an increased threat of advancement of pericardial disease among sufferers with cancers and a pericardial event with an ICI was connected with a development towards upsurge in mortality. solid course="kwd-title" Keywords: immunotherapy Launch Immune system checkpoint inhibitors (ICIs) are monoclonal antibodies that focus on and inhibit detrimental immune system regulators and thus activate immune replies against tumor cells. The accepted signs for ICIs are raising quickly, with ICIs presently indicated for the treatment of at least 16 cancer types with over 100 ongoing trials.1 2 The use of ICIs may lead to toxicities involving a range of organ systems collectively described as immune-related adverse events (irAEs).3 The best described cardiovascular irAE is myocarditis, which may be fulminant and is frequently fatal.4C6 However, evolving data suggest that cardiac toxicities occur beyond myocarditis.7 These expanded toxicities include arrhythmias, heart failure, and atherosclerosis-related cardiovascular events.8C10 Among patients with cancer, pericardial effusions often occur due to the cancer itself, but may also develop secondary to treatment with traditional cytotoxic chemotherapy, radiation therapy, or targeted therapies.11C14 There are limited data around the occurrence of pericarditis or pericardial effusions among patients on an ICI. There have been case reports describing pericardial disease in patients treated with ICI.15 16 Additionally, in a study leveraging irAEs reported to the WHO VigiBase, pericardial disease, defined as pericarditis and pericardial effusions, represented 0.36% of all reported toxicities; this risk of pericardial disease was more than threefold higher with DSP-0565 an ICI and was more common among patients with lung cancer.17 While this methodologic approach benefits from the large sample size, interpretation is limited by the lack of a control group or descriptive demographics to allow for adjustment due to confounders. In this work, we aimed to add to the limited evidence base linking ICI therapy to pericardial disease. We were specifically interested in whether pericarditis or pericardial diseases were increased among those on an ICI compared with controls and aimed to identify the risk factors for pericardial disease or pericarditis among those on an ICI. Methods Study design, setting and population This was a single-center, retrospective cohort study. A total of 2842 consecutive patients who have received treatment with ICIs from July 2010 to March 2019 at Massachusetts General Hospital, Boston, Massachusetts were included in the study. Study design is usually outlined in physique 1. Two analyses were performed to evaluate the association between ICI use with pericardial disease and to identify risk factors associated with disease incidence. To evaluate whether the rates of pericardial disease (defined, as per prior studies, as pericarditis or pericardial effusion) were increased with an ICI, we performed a cohort study comparing incidences with a cohort of 2699 control patients with metastatic cancer who were not treated with ICIs (design 1).8 For this approach, we selected controls from all patients treated for cancer at Massachusetts General Hospital between January 1, 2008 and January 1, 2012. There were 9793 patients who met this criterion; of those, 1250 patients were excluded as they received ICIs later in their treatment course. Of the residual 8543 patients, we randomly selected controls with a.
In the transgenic mouse model of Pca, DNMT expression increases during the progressive stages of Pca, and this is associated with locus-specific nonrandom CpG island hypermethylation, as well as hypomethylation of repetitive DNA elements (17, 18)
(Figure 1) Open in another window Fig 1 Normal distribution of skin damage in a kid with atopic dermatitis


text:
Nikolaus (Anton) Graf Szécsen von Temerin () (26 November  1857 – 18 May 1926), was an Austro-Hungarian diplomat of Hungarian origin serving as ambassador at Paris at the outbreak of World War I.

Life
Born in Temerin on 26 November 1857 into the Hungarian nobility as son of Anton Graf Szécsen von Temerin (1819–1896), an Austro-Hungarian government minister. In 1896, he married Johanna Gräfin Mikes von Zabola (1866–1930) in Vienna.

Count Szécsen joined the Austro-Hungarian foreign service and served inter alia in Rome. In November 1895, he was appointed Second Section Chief at the Foreign Ministry in Vienna and was promoted to First Section Chief in January 1900. At the insistence of Count Tisza, he was appointed despite his relatively limited experience to serve as the Dual Monarchy's ambassador to the Holy See in November 1901, a prominent posting given the close connections between the House of Habsburg and the papacy.

Count Szécsen, considered an able diplomat with a "solid, practical mind and a masterful grasp of the workings of diplomacy", apparently turned down an offer to succeed Count von Aehrenthal as ambassador to St. Petersburg upon the latter's appointment as Minister of Foreign Affairs in 1906.

In early January 1911, Count Szécsen was appointed as ambassador to France, considered one of the most prestigious ambassadorships at the time, and presented his credentials on 21 March. In that capacity, he played a key role during the July Crisis in 1914. After returning to Vienna, he became a member of the Upper House (Herrenhaus) in 1916 and served as a Hofmarschall in Hungary from 1916 to 1918.

Count Szécsen had been invested as a Knight of the Order of the Golden Fleece in 1908.

His son Nikolaus was executed by Russian soldiers at Mór, Hungary, on 28 March 1945.

Count Szécsen died in Gyöngyösszentkereszt on 18 May 1926.

Notes

References

External links
 'Nikolaus Graf Szécsen von Temerin', Solving Problems Through Force
 'Szécsen Miklós, gróf', Magyar Életrajzi Lexikon

1857 births
1926 deaths
Austro-Hungarian diplomats of World War I
Austro-Hungarian diplomats
Austrian diplomats
Hungarian diplomats
Hungarian nobility
Knights of the Golden Fleece of Austria
Ambassadors of Austria-Hungary to the Holy See
Ambassadors of Austria-Hungary to France


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A brain wide chemical signal that enhances memory
How does heightened attention improve our mental capacity? This is the question tackled by new research published today in the journal Cell Reports, which reveals a chemical signal released across the brain in response to attention demanding or arousing situations.
The new discoveries indicate how current drugs used in the treatment of Alzheimer's, designed to boost this chemical signal, counter the symptoms of dementia. The results could also lead to new ways of enhancing cognitive function to counteract the effects of diseases such as Alzheimer's and schizophrenia, as well as enhancing memory in healthy people.
The team of medical researchers at the Universities of Bristol and Maynooth in collaboration with pharmaceutical company Eli Lilly & Company, studied how the release of the chemical 'acetylcholine' fluctuates during the day but found that the release is at its highest when the brain is engaged with more challenging mental tasks. The fluctuations are coordinated across the brain indicating a brain-wide signal to increase mental capacity with specific spikes in acetylcholine release occurring at particularly arousing times such as gaining reward.
Professor Jack Mellor, lead researcher from Bristol's Centre for Synaptic Plasticity, said: "These findings are about how brain state is regulated and updated on a rapid basis to optimise the encoding of memory and cognitive performance. Many current and future drug therapies for a wide range of brain disorders including Alzheimer's and schizophrenia are designed to target chemical systems such as acetylcholine so understanding when they are active and therefore how they function will be crucial for their future development and clinical use."
Professor Lowry, who led the team at Maynooth University, added: "This work highlights the importance of cross-disciplinary basic research between universities and industry. Using real-time biosensor technology to improve our understanding of the role of important neurochemicals associated with memory is very exciting and timely, particularly given the increasing multifaceted societal burden caused by memory affecting neurological disorders such as dementia."
Primary author Dr Leonor Ruivo added: "This collaboration gave us access to a new generation of tools which, in combination with other powerful techniques, will allow researchers to build on our findings and provide a much more detailed map of the action of brain chemicals in health, disease and therapeutic intervention."
The research team involved the University of Bristol's Centre for Synaptic Plasticity within the School of Physiology, Pharmacology & Neuroscience and the University of Maynooth department of Chemistry in collaboration with researchers at Lilly. The work was supported by the Wellcome Trust, BBSRC and Lilly.
Caroline Clancy
caroline.clancy@bristol.ac.uk
@BristolUni
http://www.bristol.ac.uk


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cp ../java/jodd/util/buffer/Fast*Buffer.java .
python FastBuffer.py

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'Weird Al' Yankovic Polarizes Fans with Childish Gambino Parody 'This Is My Hair I Cut'
By Dan Rice | June 3, 2018
LOS ANGELES — "Weird Al" Yankovic's "This is My Hair I Cut," a parody of Childish Gambino's extremely popular "This is America," has exposed a deep divide in his fanbase, officials of the "Weird Al" fan club confirmed.
"The message boards have been going wild ever since he released the video. Some longtime fans condemned it as insensitive and inappropriate," said "Weird Al" forum moderator Jesse Plitsky. "But, a lot of fans also praised it as his most relevant work since 'Smells Like Nirvana.' Al has always thrived on controversy, so I'm sure he's loving the discussion."
The video, which opens with a shirtless, dancing Yankovic approaching a man bound to a chair, pulling out an electric razor and shaving his hair clean off, has drawn criticism for undercutting a poignant message about gun control and race in the U.S.
"Mr. Yankovic should have just left this one alone," said music critic Sean Androtelli in a recent blog post. "'This is America' was an artistic masterstroke of relevant social commentary. To reduce that to a song about cutting hair for some reason is tasteless and irresponsible… and, also, I don't really get it."
White Guy Excited to Finally Sit Down and Miss the Point of Childish Gambino Video
10-Year-Old Music Snob Prefers Weird Al's Non-Parody Works
31-Year-Old "Weird Al" Yankovic Fan Has No Clue What Is Being Parodied on Latest Album
Meanwhile, the comment section on the official Youtube video is rife with diehard "Weird Al" fans jumping to the artist's defense.
"What about that part towards the end — where the music pauses, and instead of taking out a joint, he pulls a ham sandwich out of nowhere and takes a bite?" asked Eatitguy713. "Come on, guys. This is 'Weird Al' at his peak! At the end, when he's running and playing the accordion… that is pure talent."
But Androtelli disagrees.
"The scene where Glover kills that church choir is an obvious reference to the Charleston shooting. To replace it with 'Weird Al' using a giant hair dryer to blow the hats off of a barbershop quartet undermines an incredibly important message," said Androtelli. "Also, I objectively do not see how it's funny. Is this all he does? Makes things about things they aren't? Seems kinda easy."
Despite the controversy, Yankovic's representatives confirmed he is still planning to release a full-length polka version of Kendrick Lamar's Pulitzer-winning album, DAMN.
The Hard Times Blog
Report: It's Starting to Look Like She's Not Going to Follow You Back
By Dicky Stock
Where Were You When You Learned of Kurt Cobain's Tragic Suicide and Are You Busy Right Now and If Not Can You Drive Me to the Airport?
By Jon Wood
Guess Who Cheated: Couple Celebrating Anniversary Online Have "Been Through So Much Together"
By Alexandra Houle
We Tried To List The Pros and Cons of Selling Out But Can Only Think Of Pros
By John Danek
Kentucky: It's Time to Ignore How Fucking Sexy He Is and Vote McConnell Out
Hard Times Podcast Network
Episode 7: Contributor/Musician Jordan Breeding
This week on The Pitch Group we talk with Hard Times contributor and senior writer at Cracked.Com, Jordan […]
Goth's Not Dead
This week on Fanboys, the guys rush to the defense of a beleaguered Bruce Springsteen, reluctantly crown a second Hall […]
Do You Princess Toadstool Take This Koopa…?
Today's episode makes a whole bunch of no sense. Mario and Luigi go fishing, even though they have plans to go to […]
The Hard Times Podcast w/ Walter Delgado
Matt and Bill are joined by Rotting Out's Walter Delgado to talk about prison and weight training. You know, […]
Episode 6: Hawaii Punk with Kevin Tit
This week on The Pitch Group we talk with stand up comedian and musician Kevin Tit. From Hawaii, to Germany, to […]
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Opinion: Do You All Hate Me?
By Nick Ortolani on June 30, 2019
Like, seriously. I'm asking honestly, do you all hate me? I don't know, maybe I'm just being paranoid but I sometimes feel like you're all talking behind my back or...
Opinion: No, You Forgot the Fucking Aux Cable
By John Danek on June 26, 2019
I can't believe we're finally heading to Ozzfest! We've been talking about this for years and it's finally happening. Where else can you find the taint-shaking talents of Rob Zombie,...
Opinion: I'm Just a Girl, Standing in Front of a Boy, Asking for His Birth Time
By Krissy Howard on June 23, 2019
Hey you. It's me. I need to ask you something and I hope you'll be honest with me. I know you've been hurt before by people who are quick to...
Opinion: Miles Davis Played Ska
By John Danek on May 21, 2019
Virtuoso. Iconoclast. Visionary. Ska pioneer. These are just some of the terms used to describe legendary jazz/ska trumpeter Miles Davis. He never once confined himself to the boundaries of genre...


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In 1983 Lt Colonel Jeff Cooper helped introduce the 10mm Auto that was then offered in the introductory Bren Ten pistol. While the pistol did not meet with commercial success it did get some publicity on MIAMI VICE. The 10mm Auto was designed to bridge the gap between the stopping power of a .45 acp and the penetration of the 9mm. It was briefly adopted by the FBI in 1989, but its considerable recoil made it difficult for many agents to control. The result was the development of the .40 Smith & Wesson, a shortened 10mm Auto. Despite the FBI's abandonment of the 10, it was well received by sportsman shooters since and is prized as a self defense round with considerable stopping power. The 180 grain jacketed hollow point (JHP) round has a muzzle velocity of 1180 feet per second with over 550 foot pounds of energy. Self defense to "black bear medicine", Hornady is good for what ails you.
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I love this book. Can't believe I just said that, but it's true. Something about Triplett's style, plotting and the subject matter gave me that feeling I used to get as a kid when I'd read something that would make me giggle and squirm and be mortified at the same time, and just be thinking, "this is sooo cool." I mean, we've got astronauts, aliens, mythological beings, and even Bigfeet, Bigfoots Sasquatches, yeah those things. Triplett makes it work. And a comet is heading straight toward earth - far faster than a comet should be able to travel. Straightforward, intelligent prose with style in a fast moving adventure that takes us into orbit, beneath the earth, and even to the moon.
As fantastical as that all sounds, Triplett brings his military experience, as both Marine and Airman, to bear with just enough technical and procedural detail to make it all feel just right. His knowledge (and obvious fascination with) space travel, UFOs, and mythology is apparent throughout, and infuses the story with his bubbling enthusiasm for all things wacky - but possible.
If you haven't read it, and are looking for something seriously fun and refreshing but with real depth, then do. Right away. You won't be disappointed.


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50 GROUPS, 3 GRAND MARSHALS, 21 FLOATS
LibDay spectacle returns
By Leigh Gases
The float called the "Diaspora of FSM in Saipan" is seen with dancers from Yap getting ready to dance in front of the grandstand at the Garapan Fishing Base during the 74th, 75th, and 76th Liberation Day parade and festivities yesterday. (LEIGH GASES)
Making up for lost time, the CNMI celebrated yesterday three years' worth of Liberation Day parades that saw 50 groups, three grand marshals, and 21 floats snaking their way along a stretch of Beach Road that was lined on both sides with hundreds of spectators, some of whom have been camping out at the parade route the night before.
Billed as a celebration of the 74th, 75th, and 76th Liberation Day parades, the spectacle was on full display yesterday after being cancelled in 2020 and 2021 due to the COVID-19 pandemic, with most people choosing not to wear a mask, complete with rain before and during the parade, which seems to be a yearly occurrence, but which ultimately did not deter the hundreds of people gathered up and down Beach Road.
This year's Liberation Day theme is "Honoring Our Legacy as we Ride the Waves of Change" and was seen in the floats' designs and performances that meshed both tradition and modernization, as they made their way from the National Office Supply to Garapan Fishing Base after a slight delay due to the rain.
The start of the parade itself kicked off with the roar and booming sound of motorcycles from the Young Gunz and Harley Davidson Group, followed by the Guam Army National Guard, which joined the parade for the first time right behind the three grand marshals—Estanislao Tudela "Stanley" McGinnis, Don A. Farrell, and Michael S. "Mike" Sablan—representing one for each anniversary of Liberation Day since it was last held in 2019.
Prior to the start of the parade, House Resolution 22-21 was presented to remember and honor Elias Parong Sablan for his dedication, contributions, and sacrifices for the people of Saipan post-World War II.
The 50 groups of colorfully clothed and decorated marchers and floats also showcased their performances and presented gifts to the delegates, including Gov. Ralph DLG Torres, Sen. President Jude U. Hofschneider (R-Tinian), and various U.S. military VIPs who were present.
Separately, in his message in the Liberation Day program, Saipan Mayor David M. Apatang said this year's celebration of Liberation Day will be his last as mayor of Saipan as he will complete his term next year.
"As in all past Fourth of July Liberation Day celebrations since you made me your mayor, I owe you and all the Liberation Day committee volunteers that I had the honor of working side-by-side my profound gratitude," he said.
"Working together with many Fourth of July Liberation Day celebration volunteers in my eight years as your mayor has been a very refreshing and rewarding experience. I am blessed by your professionalism and enthusiasm to share your incredible talents in making each year's celebration an event for our residents and visitors to always remember. You are now a part of our island's history and your individual and collective contributions in our traditional Fourth of July Liberation Day events will be the legacy others after would, I am sure, emulate for all future generations that call our island of Saipan home. I want to take this opportunity to thank the sponsors of the Fourth of July Liberation Day celebrations for all the years I have served as the mayor of Saipan."
Later, when asked about the turnout of the parade and festivities, Apatang said, "I'm very happy for today's celebration. The community is all out today to watch the parade and I'm very happy that we have this many floats today. It's a very tremendous day for us as it's the first time we have this in the last couple of years. I want to thank our community for continuing to support our July 4 activities."
In fact, hours after the parade ended at noon, hundreds of people were still lined up along Beach Road, continuing their celebration with families and friends in tents and picnic tables that had been installed along the highway's sides.
Festivities for this year's Liberation Day Fair began last Thursday, June 30, and has over 60 booths.
Last night capped off the festivities with an explosive fireworks display over the Garapan Fishing Base.
Leigh Gases
Leigh Gases is the youngest reporter of Saipan Tribune and primarily covers community related news, but she also handles the utilities, education, municipal, and veterans beats. Contact Leigh at leigh_gases@saipantribune.com.
CNMI's 2022 PWS is OK'd
Fuel prices down 15 cents
'Our voices are not being heard'
'Some 200 employees will be let go'
Reminders on ARPA terms were ignored—Villagomez
Alleged 'FAM tour' denounced
CCC office is temporarily closed
'Unprecedented financial crisis'


This poem was written by the well known Shetland poet, Christine De Luca. As a child, Christine and her family spent their summers with the Dunn family at Portlethen Manse. Out of all the poems within the poetry section this one is my favourite.
I'm indebted to Marilyn Stronach (formerly Dunn) and her family for allowing me to use this poem here. Thanks are due to Christine as well. If, like me, you enjoy this poem you can find find out more about Christine and her work on my links page.
Like 'future', 'past' seemed arbitrary.
For us on holiday it was mildest magic.
of comparisons of beaches, fair rides.
flick change into compartments of a pouch.
and snappy hat, this was a job to covet.
Was like riding to the stars.
grown, scattered, made new alliances.
across the line, looks out of scale.
is a pilgrimage of mind and heart.
gentle syntax of so many futures.


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Branded Content: Sanwo-Olu to launch MIT's Senseable Lagos Lab at Isimi Lagos Tech Valley
Akelicious — December 14, 2022 1 comment
LandWey Investment Limited, one of Nigeria's foremost real estate firms, is still on its mission of building future cities.
In line with its commitment to combine technology and nature in its New Town Development projects, LandWey in collaboration with the world-renowned university, Massachusetts Institute of Technology, MIT and the Lagos State Government, is set to launch the Senseable Lagos Lab in Isimi Lagos Tech Valley.
The world-class facility will be launched with a ground breaking ceremony at its designated location within Isimi Lagos, Epe, on Thursday 15th of December presided by the Lagos State Governor, Babajide Sanwo-Olu.
The launch ceremony is part of the line-up of activities for the Lagos Future City Week organised by LandWey in partnership with the Lagos State Government, and the Lagos State SDG & Investment MIT's research initiative, Senseable City Labs, aim to radicalise the way we study and understand cities globally. Through design and science, the lab hopes to develop and deploy tools to anticipate and monitor changes in urban cities just like Lagos, Nigeria.
With over 121 awards and 33,216 citations associated with the lab, its launch in Lagos is set to produce discoveries that will help to achieve national sustainable development.
Commenting on the prospects of the Senseable Lagos Lab, Olawale Ayilara, Chief Executive Officer, Oxygen Holdings, the parent company of LandWey remarked, "We have always placed technology and innovation at the core of all our developments, it is therefore no surprise that we are proud to announce the launch of the Senseable Lagos Lab to be located within the Isimi Lagos Tech Valley. We are hoping that this collaboration will give rise to innovations and breakthroughs to propel Lagos and Africa at large to the forefront of the global technology movement as we work towards our sustainability goals."
READ ALSO National Honours: Call To Greater National Service – Orelope-Adefulire
MITs Senseable City Lab is affiliated with other world-renowned academic institutions such as the University of Tokyo, Weizmann Institute of Science, Universidad Autónoma de Occidente, Instituto Politecnico Nacional, Imperial College London, Università di Pisa, KTH Royal Institute of Technology, AMS Institute.
The research initiative is as fluent with industry partners as it is with metropolitan governments, individual citizens, and disadvantaged communities. This potent addition to Isimi Lagos Tech valley aids LandWey in actualising its vision of creating an ecosystem for stakeholders who produce tech ideas, inventions, and solutions that will alter the future of living through technology.
Isimi Lagos, the first wellness technology-powered eco city offers a serene space for both living and working, to its long- and short-term citizens and visitors. Located within the long stretches of green vegetation that make up Epe in Lagos, Isimi Lagos is a 300- hectare destination city for those who love a fusion of beautiful architecture, technology, and nature. This makes it the perfect destination for the omni-disciplinary approach to research that the Senseable Lagos Lab will follow. Designers, planners, engineers, physicists, biologists, and social scientists amongst others now have a safe haven that encourages innovations and can reshape the way we live in the coming years.
Enugu 2023: Anglican Bishop Under Attack For Kneeling Before, Peter Mbah
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Atiku Visits Sultan Of Sokoto (Photos)
Pingback: Branded Content: Sanwo-Olu to launch MIT's Senseable Lagos Lab at Isimi Lagos Tech Valley Akelicious - powermeentrepreneurs


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Home»Discoveries»Inside Lisbon's New Small Grand Hotel: Hotel Das Amoreiras
everett / January 10, 2023 / 0 / 1.1k
Coffee is served in the breakfast room at Hotel das Amoreiras. PHOTO FRANCISCO NOGUEIRA
By Ann Abel
The best small hotels are nearly always passion projects and labors of love. Lisbon got its latest proof of this in October, with the arrival of Hotel das Amoreiras, a 19-room oasis beside one of the city's most beautiful small parks.
Pedro Oliveira, who founded the new hotel along with his wife, Alicia Valero, has had a lifelong love affair with hotels. "Our family had a rich cultural life," he recalls of the years they spent as emigrants in London. "We would go to exhibitions and monuments, and also for tea in hotels—just to see the [grand] hotels … continue reading
Ann Abel is a travel writer and editor and was a senior editor at ForbesLife. She writes for Forbes, Departures, Conde Nast Traveller, Robb Report, Afar, National Geographic Traveler, Islands, Hemispheres, Brides, Modern Bride, Well + Good NYC, and other print and online publications."In the name of lifestyle journalism, " she says, " I've gotten a tattoo in Bora Bora, been bitten by a massage therapist, and flown small aircraft above three continents." She lives in Lisbon.
Tags:Hotel das AmoreirasLisbonPedro OliveiraPortugalsmall hotels
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