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Administrative / News / Ophthalmology / Stem Cell / USC's Mark Humayun to receive National Medal of Technology and Innovation
USC's Mark Humayun to receive National Medal of Technology and Innovation
Mark Humayun will receive the National Medal of Technology and Innovation.
UPDATE: Officials at the White House have announced the postponement of Friday's National Medal awards ceremony because of extreme weather forecast in the Washington, DC, area. Mark Humayun, MD, PhD, was scheduled to receive the National Medal of Technology and Innovation from President Barack Obama. The ceremony will be rescheduled to spring, officials said. The original article is printed below.
President Barack Obama will bestow the National Medal of Technology and Innovation to USC University Professor Mark Humayun at a ceremony in Washington, D.C.,on Jan. 22.
Humayun, who holds joint appointments at the Keck School of Medicine of USC and the USC Viterbi School of Engineering, is a University Professor, the inaugural Cornelius Pings Professor of Biomedical Sciences and professor of ophthalmology, biomedical engineering, and cell and neurobiology at USC.
He earned worldwide acclaim through his development of a retinal prosthesis system that helps individuals with a certain type of blindness to see. A recent iteration of that system, the Argus II, became the first retinal implant to receive FDA approval two years ago.
"Mark Humayun is such a deserving recipient of this prestigious honor," said USC President C. L. Max Nikias. "He dreamed the impossible: to help the blind see. With fearless imagination, bold leadership and biomedical expertise, he and his team made that dream come true with the world's first artificial retina. USC is tremendously proud to be Professor Humayun's academic home."
"The level of recognition is very exciting and very much a surprise," Humayun said. "I'm honored to be the recipient of this award."
The Argus II system restores some visual capabilities for patients whose blindness is caused by retinitis pigmentosa. RP is an inherited retinal degenerative disease that affects about 100,000 people nationwide.
"Science and technology are fundamental to solving some of our nation's biggest challenges," Obama said in a White House news release announcing the National Medal of Technology and Innovation honorees. "The knowledge produced by these Americans today will carry our country's legacy of innovation forward and continue to help countless others around the world. Their work is a testament to American ingenuity."
Humayun joined USC in 2001 after receiving his bachelor's degree from Georgetown University, MD and residency in ophthalmology at Duke University Medical School, PhD in biomedical engineering at the University of North Carolina and advanced fellowship training in retinal surgery from Johns Hopkins School of Medicine. In 2013, Humayun was named the inaugural director of the USC Eye Institute and interim chair of the USC Department of Ophthalmology.
He holds more than 100 patent and patent applications, and is a member of both the U.S. National Academies Institute of Medicine and the National Academy of Engineering. Humayun serves as the director of the National Science Foundation BioMimetic MicroElectronic Systems Engineering Research Center, and is the director of the Department of Energy Artificial Retina Project.
R&D Magazine named Humayun "Innovator of the Year" in 2005 for his work on the Argus II.
Dozens of patients
The Argus II is manufactured by Sylmar-based Second Sight. It was first approved for use in Europe in 2011 and has been implanted in dozens of patients in clinical trials – often by Humayun himself.
The system uses a camera mounted on special glasses that sends a signal to an electronic receiver with 60 electrodes that is implanted inside the eye. The receiver sends signals to the retina that travel through the optic nerve to the brain, where they can be interpreted as a visual picture.
Humayun has said that he hopes one day the device can be improved to also help individuals with age-related macular degeneration, a similar but far more common disease.
"These sort of things can only be accomplished if others join in and help you, and I've been very fortunate to have strong collaborators," he said.
Humayun, who flew to the East Coast yesterday for the holidays, got the news when he arrived.
"It was a complete surprise. I'm still not sure who nominated me," he said. It does, however, explain the call he received six weeks ago from the FBI, wanting to conduct a background check.
"I thought it was a hoax at first," he said. Even after he answered their questions, the federal officials declined to reveal the purpose of the check – but left Humayun with the suspicion that he'd be meeting someone very important.
Which, in about a month, he definitely will.
The National Medal of Technology and Innovation was created in 1980 and is administered for the White House by the U.S. Department of Commerce's Patent and Trademark Office.
"The award recognizes those who have made lasting contributions to America's competitiveness and quality of life and helped strengthen the nation's technological workforce," according to a White House statement. An independent committee representing the private and public sectors submits recommendations to the president.
Humayun and his colleagues' efforts to improve the lives of RP patients is an example of USC's commitment to tackling what Provost Michael Quick describes as "wicked problems" – difficult and multifaceted issues that require collaboration across several disciplines.
USC's breadth of research and programmatic areas collectively create a strong community to make influential contributions to address these problems – creating both an opportunity and an obligation for the university.
by Robert Perkins
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Check out a quartet of shows from Craig Finn & his Brooklyn bandmates.
Craig Finn and his Brooklyn bandmates in The Hold Steady were feeling particularly generous a few weeks back: They posted not one, not two, but four live recordings to their Bandcamp camp. And they're all downloadable for whatever you want to pay — including nothing. Two of the shows date back to Chicago in 2017, while the other pair were recorded this summer in Philadelphia. For my money, the essentials are the first night in Philly and the second night in Chicago (which includes a seat-of-the-pants cover of Cheap Trick's Southern Girls with the help of Kelly Hogan and Jason Narducy). But since all the set lists are somewhat different, your mileage may vary based on your personal faves. Suffice to say they were all massive nights. And cheap at twice the price. Check them all out below.


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Q: Checking if class has active, if so run external .js file? Possible? So I'm currently developing a small website for someone over at http://carrotcrunchpvp.comule.com/.
On the 'our ethos' page, I have a svg running for the radial percentage stats. If you load this page, http://carrotcrunchpvp.comule.com/#horizontal/1 you will notice that there is animation on this SVG which loads it round to the defined % which is in the HTML. This is all done by my javascript file - percentagecircles.js.
Now, my question is, as the animation is triggered by running the file percentagecircles.js, is there any way to run this file ONLY when on the 'Our Ethos' page. For example if you load the homepage, the animation will run when you can't see it.
I am using FullPage.js plugin in the backend. I have noticed while developing that when traversing each page, the class="slide fp-slide fp-table" becomes class="slide fp-slide fp-table active" when on that page.
Logically I would imagine I would use an if function which says, if '#fullpage > div > div.fp-slides > div > div.slide.fp-slide.fp-table has class ;active' (our ethos css path), run the percentagecircles.js file. Seems simple to me retrospectively but my Jquery + Javascript knowledge is very very minimal...
Just a note, I've tried using a couple of plugins like Wow.js and onScreen.js to no success, perhaps I wasn't utilising them right.
Any help is appreciated,
Cheers,
Chris

A: You need to make make use of the callbacks provided by fullPage.js such as afterSlideLoad or afterLoad.
You will find them explained in the documentation.
And you have available examples such as callbacks.html here.
This way you can get the active slide and work with it.

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Discipleship Team – First Church of Christ (Holiness) U.S.A.
The Bible Bowl Team is a group of young people ages 6 – 18 that engages in an in-depth study of the Word of God. The team participates in Bible quizzes and competes annually at the Eastern Diocese Youth Conference and the COCHUSA National Convention.
Children's Church teaches God's – chronology, doctrines, commandments, precepts – thus enabling God to shape the hearts and minds of children to become faithful disciples and develop personal relationships with our Lord and Savior Jesus Christ.
The First Church Bible Institute is the Christian Education arm of First Church of Christ. The courses offered are structured to guide participants through an in-depth study of the word of God; thereby supporting members in maturing into faithful disciples of Jesus Christ. The Institute's Courses include New Disciples Training and The Master Life Discipleship Training. In addition to the course offerings, The First Church Bible Institute also offers Workshops, seminars, and retreats.
The Master Life Discipleship course utilizes a sequential, developmental process which helps Christians become deeply grounded in biblical doctrine; and grow into mature disciples of Jesus Christ. The course consists of four six-week studies which involve daily workbook assignments as well as weekly group meetings for accountability. Currently, the course begins three times a year: September, January, and March.
(1) Spending Time with the Master, (2) Living in the Word, (3) Praying in Faith, (4) Fellowshipping with Believers, (5) Witnessing to the World, and (6) Ministering to Others. The foundational scripture for the Master Life Course is Luke 9:23: "If any man will come after me, let him deny himself, take up his cross daily and follow me." Master Life course begins three times each year: September, January and March.
The Pearl Clark Scholarship Fund provides financial resources and encouragement to eligible college-bound high school students, and returning undergraduates. The mission of the Pearl Clark Scholarship Fund is to foster academic and spiritual growth in Christ. Over the past 34 years, monetary gifts were granted to over 200 students.
Established in 2015, this scholarship honors the memory of Edna Douglas Dancil, a staunch disciple of Jesus Christ who believed in sacrificial giving. The scholarship reflects the ongoing commitment to the education of young people and service to the community.
Sunday School promotes spiritual growth in the body of Jesus Christ by providing participants an opportunity to engage in Bible study in a less formal atmosphere than Sunday services. We encourage active participation as all lessons are designed to be practical, relevant, and engaging. In-depth discussions reinforce ideas or misconceptions and can serve as a blessing to others.
It's energized and over the top! Relevant and spiritually edifying! Youth and Young Adults engage in discussions directly from the headlines of today and make personal connections to their own lives as well as to the world around them. Learn to use the word of God to navigate life and stay in Christ!


Announcing a new style of living for downtown Austin, 404 Rio Grande is the ultimate living, Austin style. This impeccably designed community provides modern apartment homes with the finest finishes and amenities combined with the best downtown location. Your new home is constructed with a sentiment of historic Austin located in the center of the city with all the amenities you expect. Start living Austin style. Contact Apartment Ninjas at 800-519-0071 for the best prices on rent at apartments in Austin, Texas.


If you want to communicate well in any language it's difficult to have one without the other. For this reason, I think the question itself is somewhat misguided. Is the implication that we have to spend time alternating between learning grammar rules and lists of words?
I find rules confusing and I'm sure I'm not the only one. If I had to stop speaking to think about grammar rules I would never say anything. For example, earlier today I was preparing a class for next week which focusses on using adverbs. The rules say that adverbs usually go after the verb but that we use modifying adverbs with adjectives or other adverbs and modifying adverbs always go before the adjective or adverb. If I try to teach that then I have to teach my students what a modifying adverb is and we get lost very quickly.
Learning individual words is also full of dangers for people who want to communicate. Here's another example. Last week in a class, I was asked what the word 'range' means. The student had gone to the translator app in her phone and was confused by the result. The word given as a translation meant 'distance' which is correct in some situations. However, in this case, 'range' was being used with the word 'mountain'. A mountain range is a line or group of mountains.
So what should we do to make learning less confusing?
Remember that one language is not simply a translation of another language. They are different because they have different origins and relate to different cultures. Learning the phrases that these cultures use will help us to communicate with them much better than just learning rules and individual words.


text:
Les Mikado série 42.100 numéro 42.101 à 42.140 étaient des locomotives-tender qui furent construites par l'Administration des chemins de fer de l'État, pour le service sur les lignes de la banlieue parisienne de Paris-Saint-Lazare.

Genèse
Vers 1930, le réseau de l'État avait décidé de moderniser son parc traction, en faisant construire de nouvelles locomotives reproduisant les modèles de la Compagnie des chemins de fer de l'Est comme les Décapod 150-001 à 195 et les Mountain 241-001 à 041.

Poursuivant ce même principe, le réseau de l'État fit construire une série de quarante Mikado-tender numérotées dans la série 42.100, et reproduisant les 141-701 à 742 de l'Est. Les machines furent livrées en 1932 et 1933 par Schneider pour les 42.101 à 42.120, et Batignolles-Châtillon pour les 42.121 à 42.140.

Description
La chaudière était équipée d'un foyer « Belpaire » à grille étroite, comprenant deux tubes de circulation d'eau supportant la voûte en briques réfractaires, et d'un surchauffeur « DM3 » à vingt-et-un éléments. Le régulateur était installé dans le dôme, et la chaudière protégée des surpressions de vapeur par deux soupapes de sûreté types « Coale ». L'alimentation en eau contenue dans les deux soutes à eau latérales et une troisième placée à l'arrière sous la hotte à charbon, se faisait à l'aide de deux injecteurs universels en charge.

Ces machines étaient équipées d'un moteur à trois cylindres à simple expansion avec une distribution du type « Walschaerts », le deuxième essieu couplé étant coudé pour recevoir la bielle motrice du cylindre interne. Cette configuration à trois cylindres alliée à des roues de petit diamètre en faisaient des locomotives aux accélérations rapides et à l'effort de traction très important.

Les bissels avant et arrière étaient typiquement « Est » à châssis non suspendu.

L'ensemble de la série fut équipé d'origine de la conduite par réversibilité. Elles reçurent par la suite quelques modifications comme la pose d'écrans pare-fumée, d'un réservoir-doseur de traitement « T.I.A », et d'un échappement « Kylchap » permettant une meilleure utilisation de ces machines.

La vitesse limite en service de  était relativement élevée pour ces locomotives, malgré des roues motrices d'un diamètre de .

Utilisation et services
Avec leurs congénères 141 T 42.000, les 42.100 partagèrent la traction des trains de banlieue constitués de rames Talbot et de voitures à deux niveaux État, en réversibilité au départ de Paris-Saint-Lazare sur les lignes de Paris-Mantes par Poissy et de Paris-Mantes par Conflans-Sainte-Honorine jusqu'en 1967. Elles assurèrent également du service banlieue sur Gisors, de Mantes à Plaisir - Grignon, ainsi que la traction de trains de marchandises sur les lignes électrifiées en  par troisième rail de Versailles-Rive-Droite et de Saint-Germain-en-Laye, de même que jusqu'à Trappes par la grande ceinture.

Elles furent affectées au dépôt des Batignolles, mais aussi à Mantes et Achères.

À la création de la SNCF, elles seront immatriculées 3-141 TD 101 à 140. L'une d'entre elles, la 141 TD 139, sera détruite pendant la seconde guerre mondiale.

Au début des années 1950, sept locomotives supplémentaires de conception identique et provenant de la région Est, seront mutées au dépôt des Batignolles puis numérotées 141 TD 703, 709, 720, 736, 740, 741 et 742.

Le , lors la mise sous tension de l'intégralité de la ligne de Paris-Mantes par Conflans-Sainte-Honorine, la 141 TD 119 de Mantes assurera la traction du dernier train de banlieue en traction vapeur sur Paris-Saint-Lazare, clôturant ainsi l'ère de la vapeur dans cette grande gare parisienne.

La 141 TD 740 fut préservée par la SNCF en 1968 pour figurer au Musée français du chemin de fer de Mulhouse, mais le projet fut abandonné et la locomotive rachetée en 1982 par l'association CFTLP qui restaurera la machine en état de marche, afin d'assurer la traction de trains spéciaux.

Notes et références

Voir aussi

Articles connexes
 Locomotives à vapeur françaises
 Voitures OCEM « Talbot »
 Voiture à étage État

Locomotive à vapeur française
Matériel roulant de l'État

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Tom Hiddleston is already a Disney prince of sorts, but he'll dive even deeper into the Mouse House next spring. A few months back, it was announced that Hiddleston and Christina Hendricks had signed on for The Pirate Fairy, a sort of Peter Pan spinoff about Tinkerbell (Mae Whitman — yes, her), a badass fairy named Zarina (Hendricks), and the cabin boy (James) she falls for.
Unfortunately for Zarina, the object of her affections may not be quite as sweet and innocent as he looks. It turns out his name is James Hook, as in Captain Hook, although The Pirate Fairy takes place before that crocodile took his hand. A new trailer has just arrived, and you can check it out after the jump.
Yahoo! Movies got the new trailer. It mostly focuses on Tinkerbell and her gang, but it offers glimpses of Zarina and Hook as well.
Frankly, Hiddleston's presence in The Pirate Fairy seems kinda random. He's a big enough name that he seems like he should be leading in one of their live-action theatrical releases, not cropping up in a supporting role in a direct-to-DVD animated spinoff. And it's not like Disney's unaware of Hiddleston's appeal. His Loki is one of the Marvel Cinematic Universe's brightest stars. But who knows — maybe he was just really into the idea of playing a young Captain Hook.
Other than the cool voice cast, The Pirate Fairy doesn't seem to have much to entice adults. The trailer is cute and mildly entertaining, but it's also very definitely aimed at kids and not their parents.
The Pirate Fairy lands sometime next spring.
When a misunderstood dust-keeper fairy named Zarina steals Pixie Hollow's all-important Blue Pixie Dust, and flies away to join forces with the pirates of Skull Rock, Tinker Bell and her fairy friends must embark on the adventure of a lifetime to return it to its rightful place. However, in the midst of their pursuit of Zarina, Tink's world is turned upside down. She and her friends find that their respective talents have been switched and they have to race against time to retrieve the Blue Pixie Dust and return home to save Pixie Hollow. With comedy, heart and epic thrills for the whole family, "The Pirate Fairy" sets sail Spring 2014.


Jonathan Rea says he needs an improved package from Kawasaki after the reigning World Superbike champion fell further behind in his bid for a record fifth title at Assen on Sunday.
Alvaro Bautista sealed a double at Assen to make it a staggering 11 successive victories in his maiden season in the World Superbike Championship.
Jonathan Rea had to settle for the runner-up spot for the tenth race in a row as Alvaro Bautista made history at Assen on Sunday.
The opening World Superbike race at Assen has been cancelled due to heavy snow and hailstone showers.
Jonathan Rea was second fastest overall in free practice at Assen on Friday as World Superbike Championship leader Alvaro Bautista ended the day sixth quickest on the combined times.
Peter Hickman accepts he will start the new road racing season on the back foot following the late delivery of his new Smiths Racing BMW.
Michael Dunlop was forced to wait a little while longer to ride the new Tyco BMW S1000RR after missing Tuesday's official Bennetts British Superbike test at Silverstone.
A tribute night in memory of William Dunlop will be held at The Anchor Bar in Portstewart during this year's North West 200.
Jonathan Rea is already looking towards Assen this weekend as the World Superbike champion aims to put the brakes on new title favourite Alvaro Bautista.
Spain's Alvaro Bautista tightened his grip on the World Superbike Championship as the Ducati rider won an incredible ninth race on the trot at Motorland Aragon on Sunday.
Alvaro Bautista doubled up at Aragon in the Superpole race as he made it eight World Superbike wins in succession on Sunday.
Unstoppable Alvaro Bautista was in seventh heaven as the Ducati rider once again blitzed his rivals to extend his lead in the World Superbike Championship over Jonathan Rea.
Man of the moment Alvaro Bautista topped the times in free practice on day one at Motorland Aragon, with World Superbike champion Jonathan Rea third fastest.
Rising star Adam McLean is hoping for a change in fortune at this year's fonaCAB International North West 200 in association with Nicholl Oils.
World Superbike champion Jonathan Rea has vowed to 'give it my all' as he attempts to close the deficit to Alvaro Bautista at the top of the standing this weekend in Spain.
Four-time World Superbike champion Jonathan Rea will return to the fonaCAB International North West 200 in association with Nicholl Oils in May.
Irish road racing legend Phillip McCallen is on a mission to stage the world's biggest collection of Joey Dunlop race bikes at the inaugural Classic Bike Festival Ireland in August.
Michael Dunlop is set to make his debut in the notorious 'Race to the Clouds' Pikes Peak International Hill Climb in June.
There is no question the addition of John McGuinness and the factory Norton to an already stellar North West 200 line-up would be the icing on the cake, but rules are rules.


This book will present recent research advances in designing efficient clustering methods and tools for analyzing Big data and their innovative applications in contemporary AI systems, such as information retrieval, text mining, recommender systems, smart cities, Internet of things, digital and mobile health, human-robot interaction, social network analysis, etc.
The large volume and variety of data, being generated at an accelerated velocity, creates an important opportunity and challenge for humans and organizations. Data has become the lifeblood of today's knowledge-driven economy and society. Unfortunately, conventional unsupervised learning techniques, especially clustering, face tremendous challenges when mining such data due to its high complexity, heterogeneity, large volume and rapid generation. This raises exciting challenges for researchers to design new scalable and efficient clustering methods and tools that are able to extract valuable information from data.
The goal of this book is to provide a coverage of recent developments in big data clustering methods, tools, frameworks, applications, representation, visualization, and validation measures for analyzing Big Data.
Feel free to contact the book editors via email (olfa.nasraoui@gmail.com and chiheb.benncir@gmail.com) regarding your chapter ideas.


This adorable, one of a kind,~one level home features neutral decor, 4 bedrooms 2 baths with oversized master suite, washer/dryer room, huge yard with a beautiful deck, large storage shed, located in a quite cu-de-sac, close to Prince William Parkway, schoools,shopping and resturants. Hardwood floors in living area, tiled bathrooms and kitchen, carpeting in bedrooms. Enjoy a beautiful home with a backyard secluded by greenery.


text:
Q: Letting users define sender of an email a client asked me about a little form for his website, from which it would be possible to mail the URL to someone. Something like "Hey check this out".
Since he was not happy with mailto:, I want to use PHP mail() function, but i wonder if it is smart to let users define a sender of the email. I am worried about the form being abused for spam/phishing.
Is that a reason to worry? Is it even legal?

A: Setting the From on an email in php mail isn't the cause for concern. The problem is that you'll be sending emails from your server. The mail headers will have your server information embedded - so any issues will tie back to you.
As long as you can safeguard your own server from allowing these spam/phishing attacks, then there's nothing wrong with it.
Just limit the number of people this mail function can send to - and make sure it can't be called multiple times in succession -- like with a script.
This way, the spammers wouldn't benefit from using your page to try to send spam. They'll go elsewhere.
There's much more to do to work with sending email, but this will at least get you started.

A: It's legal to send e-mail. It's not legal (everywhere) to send spam. But you are just providing a share link, not a relay server, so I wouldn't worry about that. If you limit the amount of control over the content of the message, and limit the number of people to send it to, it won't be too interesting for spammers.
Letting the user choose a sender is not a very good idea. Some mail relay servers check if the originating server is allowed to send e-mails for the domain specified in the address, so the mails might never arrive. You can safely set the sender name, though.
Apart from that, if the receivers of the message consider it as spam and report it, your domain might become blacklisted, and your mails will be sent to junk mail in many cases, so you want to make sure no (or little) spam is sent through your form.
Those bots try every form automatically just to see what happens, so you'll need to make some effort. You could add a captcha, which is an obstacle for humans too, although Google is going to put an end to that. Or you could protect it through other means, like a honeypot. Maybe you can just generate the form through JavaScript, which is a big obstacle for most spam bots.

A: "Is it legal" depends upon the country you are in.
I don't think you need to worry about spam if you set up a login.
Or you could limit the number of emails by IP address.  This can be spoofed, however, so it may not be the best option.
There are other control options you could do; limit number of emails by User Agent/IP combination, etc.

A: Aside from the reasons pointed out by others who have answered this question, I would advise against doing this because these messages will likely be marked as spam by spam filters, due to SPF and DMARC records.
For example, is someone sends a message through your system from a yahoo.com address, most spam filters will treat the message as spam, because os Yahoo's DMARC record, which  basically says, 'any message sent from a yahoo.com email address that did not originate from a mail server on yahoo's network is spam'.  See https://help.yahoo.com/kb/mail/SLN24016.html?impressions=true for more info.


Buy freshly prepared sandwiches and just-squeezed juices and fresh smoothies to go.
A fresh blueberry muffin with freshly ground coffee tastes divine.
Our offering is freshly made. Our baristas prepare cappuccinos and espressos from the beans they grind themselves, and your glass will be filled with juice we just squeezed. We bake and prepare sandwiches on site – with tasty tomato and full-bodied mozzarella, for example.
You can also buy cold beverages, nuts and other snacks to go.


Beginning mid-December, you'll find plenty of blue and white treats amidst the red and green, like Hanukkah themed Brownie Six Packs and Cupcake Six Packs already wrapped for gift giving during the eight days and eight nights. Our Star of David Cookie Packs contain 8 shaped sugar cookies-- one for each night of Hanukkah-- decorated with blue sugar, white sugar, and sprinkles.
Order a braided Challah Bread for your Hanukkah table— available with Sesame Seeds, Poppy Seeds, or Plain. In addition, we offer a wide selection of fried donuts daily, most notably for Hanukkah are the Jelly Bismarks filled with black raspberry jam and covered in granulated sugar, as well as our Custard Bismarks dusted with powdered sugar.
AVAILABLE BY ORDER ONLY!! Dress up your Hanukkah table this holiday with the 7" Hanukkah Centerpiece Cake. Serving 10-12 people, the cake is made with three full layers of white dough, vanilla buttercream filling, and iced in smooth buttercream. For a festive finish, our decorators add a Hanukkah image, rim of silver crystal sugar, and blue borders.


David O'Russell must really love Jennifer Lawrence and Bradley Cooper. The latest collaboration of this celebrated trio is Joy, a loosely based biopic on the life of American inventor Joy Mangano. While it is a solid film fueled by yet another Academy Award-nominated performance by Jennifer Lawrence, it's also clear that Joy is a much weaker motion picture than Silver Linings Playbook and American Hustle. And I t's not even a debate.
It's hard to review Joy without discussing Mangano's life, and I suppose certain details may be considered spoilers if you've never heard of her or see the trailer (or even just the poster). But since this is Spoiler-Free Reviews, I'm just going to assume that you don't know anything at all other the basic premise: Joy is a single mother struggling to make ends meet while taking care of everyone in her family from her parents (played by Robert De Niro and Virginia Madsen) to her ex-husband (Edgar Ramirez). And yet, she still dreams big, and as the opening caption of the film will tell you, she is an inspirational woman.
As such, there is a sense of inevitability about the movie even if you don't know who Joy Mangano is. She goes through plenty of heartache and frustration and despair, but you do get the sense that everything will eventually be okay in the end. Credit to O'Russell for still keeping the story relatively intriguing, with moments of hard-hitting drama and tension — though very little comedy, which begs the question why it is listed as a comedy-drama and was nominated as a comedy at the Golden Globes (I guess if The Martian is a comedy then any movie could be one too). The pacing could have been better, as it does drag at times and feels longer than its already-long 124-minute running time.
The Academy must also love Jennifer Lawrence because I'm not sure her performance in Joy was one of the top 5 female performances of the year. Don't get me wrong, it's really really good, probably top 10, as she completely drives the movie from start to finish, though I still got the feeling that she was probably miscast — she simply looks too young and fresh-faced to be totally convincing as a single mother of three who has lived a really hard life.
Apart from Lawrence, the rest of the supporting cast deliver fine performances as well. It's more or less expected when you have the likes of De Niro, Bradley Cooper and Isabella Rossellini on the roster. However, Lawrence is the clear standout, and despite my misgivings about the suitability of her casting, she gives it everything she has to elevate the movie above what it otherwise would have been in less capable hands.
This is not Lawrence's fault, but I also felt the film was lionising the protagonist a little too much. Joy is practically a saint in this movie and it never changes despite some really nasty stuff happening to her. It may be all true, but it would have been nice to see more "human" emotions from her character to keep it interesting.
Overally, Joy is a solid and occasionally very good biographical drama thanks to the direction of O'Russell and a great performance from Lawrence. The problems I had with it perhaps lay more with the script than anything else. It's an inspirational story, but it's one that also feels overlong and somewhat repetitive in that it keeps putting Joy down so that we can all feel the joy (pun intended) when things finally start going right for her. The result is O'Russell's least impressive effort in recent years, though by most other standards it's still a pretty enjoyable film.
I don't think much of Woody Allen as a husband or father, but I still get excited whenever I hear that he has a new film out. Despite a mixed bag in recent years, I loved Match Point and thought Midnight in Paris was one of the best movies of 2011. His latest, Blue Jasmine, starring Cate Blanchett in possibly a career-defining performance, is definitely right up there as one of his better projects over the past decade.
In tradition with Allen's unique style, Blue Jasmine is a small, chatty, neurotic character movie, this time about a woman who had everything coping (or not coping) with losing everything. Blanchett plays the titular Jasmine, a New York socialite who once had wealthy husband (Alec Baldwin) and all the branded handbags and shoes a woman could want, but begins the film travelling to live with her not-so-well-off sister and her two sons in San Francisco. There are reasons for her downfall and breakdown, and we find this out gradually, piece by piece, through a series of well-designed exposition and flashbacks.
It's clear from the very first scene, a one-sided conversation aboard her flight, that Jasmine is not a likable protagonist, someone who cannot let go of her elitist attitude and high and mighty behaviour despite no longer having the status or bank balance to back it up. Much of the fun is watching this very self-centered, pompous and cluelessly tactless woman trying to "put up" with people she thinks are inferior to her, though at the same time there is a certain poignancy to Jasmine's ordeal because she is fighting so hard to not crumble under her depression. Despite all the obnoxious and insufferable things she says and does, it's no easy hating Jasmine because she's so laughably pitiful.
Part of that is Allen's masterful writing, but most of the credit should go to Blanchett's performance, which has already won her a Golden Globe and makes her a favourite heading into the Oscars. She is simply perfect as Jasmine, exuding an elegance and presence that is tailor made for the role. Everything, from her posture to the way she seems to start every sentence with a heavy sigh, tells you the kind of horrible character she is, and yet you understand why men are drawn to her. And most of all, she is incredibly funny, in an endearing Larry David/George Costanza kind of way.
Backing Blanchett up is a strong cast that includes Sally Hawkins as her "far too nice" sister, Bobby Cannavale as the sister's middle-class boyfriend, and Peter Sarsgaard as a potential new love interest. Rounding out the effective ensemble are Alec Baldwin as the sleazy husband (another wonderful bit of casting), Louis CK as the sister's new potential love interest, and Michael Stuhlbarg as a creepy dentist.
Blue Jasmine is an unusual, quietly brilliant movie because it doesn't follow Hollywood's typical "character journey" plot. Some of the subplots were a little on the predictable side — you just knew Woddy was setting certain relationships up for a dramatic moment — but by the end I was pleasantly surprised with its unconventional, and probably more realistic, conclusion. The film does lose momentum and become more serious and less funny as it progresses, but with a crafty pace and a compact 98-minute running time, Blue Jasmine is a pure delight that doesn't come around very often, even for Woody Allen.
To be honest, I wasn't really all that interested in Captain Phillips, which depicts the true story of the Maersk Alabama hijacking by Somali pirates in 2009. I dunno, maybe I had been put off by pirates because of the Pirates of the Caribbean franchise (there may actually be an element of truth that joke), or perhaps it was because it looked like another boring a Oscar bait. I couldn't have been more wrong. Captain Phillips is, without a doubt, one of the most thrilling and captivating movies of the year.
As always, if you don't know about the Maersk Alabama hijacking then don't read up about it before you go watch the movie. First of all, it's best not knowing how the story ends, and secondly, you won't be distracted by any of the creative liberties taken by the filmmakers. I went into it not knowing anything about it at all other than that it's based on a true story, and as a result I was glued to the screen for the entire 133-minute running time, which didn't feel one bit overlong at all.
To just give a basic background of the premise, the film tells the story of Richard Phillips, the captain of the Maersk Alabama who took orders to sail through the Gulf of Aden to Mombasa with aide cargo. The ship gets hijacked by a band of Somali pirates, who take Phillips hostage for ransom and sets off a major international incident. It's an extraordinary story of bravery and survival, one that I'm sure has been at least a little embellished and sped up for the purposes of the movie, but I have no problems with that at all because it worked. Apart from a brief intro, Captain Phillips is intense all the way through, rarely easing up to give audiences time to take a breather. The sense of dread is real, the fear of danger is genuine, and the action feels authentic without being not over-the-top. It's a masterful piece of filmmaking considering that almost all of it takes place on the sea, and in nothing more than a couple of boats, and yet it's far more exciting than many films that follow characters to multiple locations all around the world.
I've been a fan and critic of director Paul Greengrass, who directed two of the Bourne movies (Supremacy and Ultimatum) as well as the underrated war movie Greenzone. I like the way he handles his action sequences but I'm not a fan of his trademark handheld camera. In Captain Phillips, however, it feels as though Greengrass held back on the queasy-cam sequences, and even the scenes where the handheld cameras were more obvious were almost fitting because they were on the rocky seas.
As for the performances, I expected an Oscar-nominated one from Tom Hanks, which he delivers, but I was equally impressed by newcomer Barkhad Abdi, who has nabbed a Golden Globe as the lead pirate and I think deserves an Oscar nod too. You would think as a hostage Hanks won't get to show off his acting chops as much, but he's so solid as the stoic but clearly terrified captain and it's difficult to imagine anyone else pulling off the role the way he did. Adbi, on the other hand, is brilliant as the young leader of the pirates, who is frightening and vulnerable at the same time. All of the newcomers who play the pirates are terrific — they are the bad guys but you almost don't want anything to happen to them — but Adbi is the one who stands out the most because of his screen presence.
In all, I was very impressed by Captain Phillips. It ticks all the right boxes — riveting plot, thrilling action, just the right amount of political intrigue and well-developed characters backed by top performances. A smart, intense and highly enjoyable film.


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Get henry copeland's new animals quotes.
Acquisition of object-robbing and object/food-bartering behaviours: a culturally maintained token economy in free-ranging long-tailed macaques | Philosophical Transactions of the Royal Society B: Biological Sciences
The token exchange paradigm shows that monkeys and great apes are able to use objects as symbolic tools to request specific food rewards. Such studies provide insights into the cognitive underpinnings of economic behaviour in non-human primates. However, the ecological validity of these laboratory-based experimental situations tends to be limited. Our field research aims to address the need for a more ecologically valid primate model of trading systems in humans. Around the Uluwatu Temple in Bali, Indonesia, a large free-ranging population of long-tailed macaques spontaneously and routinely engage in token-mediated bartering interactions with humans. These interactions occur in two phases: after stealing inedible and more or less valuable objects from humans, the macaques appear to use them as tokens, by returning them to humans in exchange for food. Our field observational and experimental data showed (i) age differences in robbing/bartering success, indicative of experiential learning, and (ii) clear behavioural associations between value-based token possession and quantity or quality of food rewards rejected and accepted by subadult and adult monkeys, suggestive of robbing/bartering payoff maximization and economic decision-making. This population-specific, prevalent, cross-generational, learned and socially influenced practice may be the first example of a culturally maintained token economy in free-ranging animals.
#economics #money #abstraction #animals - royalsocietypublishing.org
'Robopets' can benefit health and wellbeing of older care home residents -- ScienceDaily
Lead author Dr Rebecca Abbott, from the University of Exeter Medical School, said: "Although not every care home resident may choose to interact with robopets, for those who do, they appear to offer many benefits. Some of these are around stimulating conversations or triggering memories of their own pets or past experiences, and there is also the comfort of touching or interacting with the robopet itself. The joy of having something to care for was a strong finding across many of the studies." Robopets are small animal-like robots which have the appearance and many of the behavioural characteristics of companion animals or pets. Five different robopets were used in the studies -- Necoro and Justocat (cats), Aibo (a dog), Cuddler (a bear) and Paro (a baby seal). Some of the studies were on older people's experiences of interacting with the robopets, while others sought to measure impact on factors such as agitation, loneliness and social interaction.
#aging #bots #animals - sciencedaily.com
I feel you: Emotional mirror neurons found in the rat -- ScienceDaily
On the basis of this, researchers formulated two speculations: (a) the cingulate cortex contains mirror neurons, i.e. neurons that trigger our own feeling of pain and are reactivated when we see the pain of others, and (b) that this is the reason why we wince and feel pain while seeing the pain of others. This intuitively plausible theory of empathy however remained untested because it is not possible to record the activity of individual brain cells in humans. Moreover, it is not possible to modulate brain activity in the human cingulate cortex to determine whether this brain region is responsible for empathy. Rat shares emotions of others For the first time, researchers at the Netherlands Institute for Neuroscience were able to test the theory of empathy in rats. They had rats look at other rats receiving an unpleasant stimulus (mild shock), and measured what happened with the brain and behavior of the observing rat. When rats are scared, their natural reaction is to freeze to avoid being detected by predators. The researchers found that the rat also froze when it observed another rat exposed to an unpleasant situation. This finding suggests that the observing rat shared the emotion of the other rat. Corresponding recordings of the cingulate cortex, the very region thought to underpin empathy in humans, showed that the observing rats activated the very neurons in the cingulate cortex that also became active when the rat experienced pain himself in a separate experiment. Subsequently, the researchers suppressed the activity of cells in the cingulate cortex through the injection of a drug. They found that observing rats no longer froze without activity in this brain region.
#pain #empathy #animals #mirror-neurons #cingulate-cortex - sciencedaily.com
Insel and "digital phenotype"
His company is working on using the technique to pre-screen for depression, post-traumatic stress disorder, schizophrenia and bipolar disorder. Their initial studies were able to link the digital features from participants' phones to how well they did on neural cognitive tests.
#medicalindustrialcomplex #depression #paleotherapy #mobile #animals - cbc.ca
The happiness project | Science
In 2010, cancer biologist Lei Cao—inspired by a family member who had died of cancer—wondered whether she could combat it by looking beyond drugs or genes. Her team at OSU created a 1-square-meter enclosure filled with so many mazes, running wheels, and bright red, blue, and orange igloos that her daughter dubbed it "Disneyland for Mice." <img class="fragment-image" src="https://d2ufo47lrtsv5s.cloudfront.net/content/sci/359/6376/624/F3.medium.gif"/> A fish at the University of Michigan in Ann Arbor gets to choose between an empty tank and one filled with marbles. PHOTO: AUSTIN THOMASON/MICHIGAN PHOTOGRAPHY When injected with cancer cells, animals housed there developed tumors 80% smaller than those in control mice, or no tumors at all. Cao even discovered a possible mechanism: A stimulating environment seemed to activate the brain's hypothalamus, which regulates hormones that affect everything from mood to cancer proliferation. "We showed that there's a hard science behind enrichment," she says. "You can't just treat the body—you have to treat the mind."
#brain #education #cancer #mind-body #training #animals #experiments #frats - science.sciencemag.org
rat enrichment
Inspired by research that showed enrichment could spark the growth of new neurons, he provided the rodents with cardboard for making nests, brightly colored balls for play, and ladders and ropes to climb. Remarkably, the animals were much slower to develop symptoms of a Huntington-like disease than their counterparts in standard housing—the first demonstration that enrichment could significantly influence neurological disorders.
#brain #paleotherapy #animals #experiments - science.sciencemag.org
Today, lab mice live in shoebox-size cages hundreds of thousands of times smaller than their natural ranges, and rats can't forage or even stand upright. Both spend their days blasted by ventilation and bright fluorescent lighting that disrupts their day-night cycles. "We're doing the exact opposite of what we should be doing to make these animals happy," Garner says. Lab animals tend to be obese, have weak immune systems, and develop cancer—all before scientists do any experiments on them.
#brain #paleotherapy #pharma #education #training #animals #experiments - science.sciencemag.org
Animals, like humans, place a higher value on what requires more effort.
We have examined the justification of effort effect in animals and found a pattern similar to the one in humans but we propose a simpler underlying mechanism: contrast between the greater effort and the resulting reward that follows. The contrast model predicts that any relatively aversive event will result in a preference for a reward (or for the signal of a reward) that follows. Much evidence supports this model: Signals for reward are preferred if they are preceded by having to make a greater number of responses, encountering a longer delay, or experiencing the absence of food (when food is presented on other trials). Contrast has also been found when the signals are associated with greater rather than less food restriction. We have also found a shift toward the preference of a food location that requires greater effort to obtain. Analogous effects have been found in humans (both children and adults) using similar procedures.
#managing #econ #investing #animals #sunk-costs - animalstudiesrepository.org
A man's best friend: Study shows dogs can recognize human emotions -- ScienceDaily
For the first time, researchers have shown that dogs must form abstract mental representations of positive and negative emotional states, and are not simply displaying learned behaviours when responding to the expressions of people and other dogs.
#emotion #animals #dogs - sciencedaily.com
Animals and fairness
At a canine research centre at Eotvos Lorand University in Budapest, for example, dogs frequently chosen to take part in tests are shunned by other dogs. It turns out that all the dogs want to take part in these tests because they receive human attention; those which are chosen too often are seen as having got unfair advantage. Capuchin monkeys taking part in experiments keep track of the rewards they are getting. If one is offered a poor reward (such as a slice of cucumber), while another gets a tasty grape, the first will refuse to continue the test. Chimpanzees do this, too.
#managing #money #animals #dogs - economist.com
Animal culture
In "The Cultural Lives of Whales and Dolphins", Hal Whitehead of Dalhousie University, Nova Scotia, and Luke Rendell of the University of St Andrews, in Scotland, argue that all cultures have five distinctive features: a characteristic technology; teaching and learning; a moral component, with rules that buttress "the way we do things" and punishments for infraction; an acquired, not innate, distinction between insiders and outsiders; and a cumulative character that builds up over time. These attributes together allow individuals in a group to do things that they would not be able to achieve by themselves.
#community #animals #culture - economist.com

redpajama_set_name: RedPajamaCommonCrawl


As the daughter of psychiatrists practicing in Tokyo, Japan, Sayaka Machizawa (Psy.D., Clinical Psychology, '05) knew from an early age that if she wanted to pursue her dream of being a psychologist, she would need to leave the country.
Psychology as a profession is viewed differently in Japan. There is currently no licensure, no national health insurance coverage, and psychologists aren't even allowed to give a patient diagnosis. "I thought that receiving clinical psychology training in the U.S. would give me better career opportunities," she says.
Today, Dr. Machizawa is a licensed clinical psychologist who in addition to practicing at clinics around Chicago, is also Associate Director of the Community Partnerships Department at The Chicago School—utilizing her research skills to implement community-based participatory research projects.
For her, this work is the best of both worlds and allows her to build bridges with her native country that will have a lasting impact on mental health.
Dr. Machizawa is also pleased with the opportunities that both her scholarship and faculty position at The Chicago School have opened for her to lead the way for the next generation of transnational feminist psychologists.