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Date of Decision 22-Apr-2010
Keywords: Autoimmune diseases, disease susceptibility, PTPN22 gene polymorphism, systemic lupus erythematosus
Pradhan V, Borse V, Ghosh K. PTPN22 gene polymorphisms in autoimmune diseases with special reference to systemic lupus erythematosus disease susceptibility. J Postgrad Med 2010;56:239-42
Pradhan V, Borse V, Ghosh K. PTPN22 gene polymorphisms in autoimmune diseases with special reference to systemic lupus erythematosus disease susceptibility. J Postgrad Med [serial online] 2010 [cited 2020 Jan 18];56:239-42. Available from: http://www.jpgmonline.com/text.asp?2010/56/3/239/68651
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the presence of autoantibodies to nuclear constituents and inflammatory lesions in multiple organ systems. The pathogenesis of SLE has a strong and complex genetic base. Molecular genetic studies, both in human and in experimental animal models, have identified important genes that contribute to SLE pathogenesis. Recently, three genome-wide association studies in Caucasian patients with SLE from international collaborations confirmed the known candidate genes for disease susceptibility, including human leucocyte antigen (HLA) like DR3, DR4, Fc gamma receptor IIA, IIIA and IIIB (Fcγ R), protein tyrosine phosphatase, non-receptor type 22 (PTPN22), signal transducer and activator of transcription 4 (STAT4) and interferon regulatory factor 5 (IRF5). [1]
The PTPN22 gene, located on chromosome 1p13, encodes lymphoid protein tyrosine phosphatase (LYP), which is important in negative control of T lymphocyte activation. LYP is expressed on T lymphocytes and associates with C-terminal Src Kinase (CSK) to form a complex that suppresses T cell receptor signaling kinases LCK and FYN. The missense R620W polymorphism in PTPN22 gene at the nucleotide 1858 (1858 C > T) in codon 620 (620Arg > Trp) has been associated with various autoimmune diseases. The disease-associated LYP variant Trp 620 prevents the interaction of LYP with CSK. Consequently, the T cell receptor-associated kinases might exhibit an uncontrolled T cell induction and this may increase the overall reactivity of the immune system thus predisposing an individual to autoimmune disease. [2]
:: PTPN22 Polymorphism - Associated Autoimmune Diseases
The first study on the 1858C/T single-nucleotide polymorphism (SNP) in PTPN22 gene and its association with increased risk of type 1 diabetes (T1D) was reported in 2004, which was further confirmed in a large population. [3],[4],[5],[6] The 1858C/T SNP in PTPN22 gene was also reported in rheumatoid arthritis (RA), [7],[8],[9],[10],[11] juvenile idiopathic arthritis (JIA), [11],[12] SLE, [8],[12] Graves disease (GD), [13] Myasthenia Gravis, [14] generalized vitiligo [15] and Wegener's granulomatosis. [16] Interestingly, some autoimmune diseases were demonstrated not to be associated with the 1858T allele, including multiple sclerosis (MS), [17] inflammatory bowel diseases (IBD) such as Crohn's disease [18],[19],[20] and ulcerative colitis, [20],[21] celiac disease, [22] primary biliary cirrhosis, [23] psoriasis and psoriatic arthritis. [11]
In addition to the 1858C/T SNP (rs2476601), there are numerous other SNPs in the human PTPN22 gene. Some of these SNPs are shown in [Figure 1]. An initial investigation of the role of these other SNPs in RA patients confirmed that 1858C/T is the major disease-associated SNP in PTPN22, but also suggested minor involvement of at least one other SNP (rs3789604). [24] Subsequent studies have supported the notion that 1858C/T is the only SNP in PTPN22 associated with RA. [25],[26],[27] Similarly, T1D patients have also been investigated with regard to other SNPs in PTPN22. Kawasaki et al., (2006) had reported that a promoter SNP in PTPN22 (-G1123C, rs2488457) confers increased risk of T1D, supporting a role for 1858C/T as the major T1D-associated SNP in PTPN22.[28] However, it is still possible that additional polymorphisms may be discovered for PTPN22 that may independently relate to different and/or overlapping groups of autoimmune disorders. Huffmeier et al., (2006) reported that 1858C/T SNP was not associated with psoriasis but that there was evidence for a susceptibility locus for this disease somewhere else in PTPN22 or in its vicinity. [29] Studies on PTPN22 gene polymorphism in vitiligo showed that the 1858T allele is significantly overrepresented in vitiligo patients, indicating that LYP missense R620W polymorphism may have an influence on the development of generalized vitiligo, which further provides evidence for the autoimmunity as an etiology factor. [15],[30]
Figure 1 :PTPN22 structure with two transcript isoforms and six single nucleotide polymorphisms
A metaanalysis has also confirmed the association between the 1858T allele and the diseases T1D, RA, JIA, SLE and GD. [31] Genetic studies with different populations revealed a clear geographic gradient with regard to the frequency of the disease-associated 1858T allele in Europe. Although this allele is relatively rare in southern European populations (2% in Italy, 6% in Spain), the frequency increases northward through Europe (8% in the United Kingdom, 12% in Sweden, 15.5% in Finland). Interestingly, in African-American and Asian populations, the 1858T allele is virtually absent, suggesting a northern European origin and/or selective advantage for the 1858T allele in this region. Nevertheless, an adequate number of studies have now been conducted to demonstrate that an autoimmune disease association with the 1858T allele is population-independent. [32]
:: PTPN22 Gene Polymorphism and SLE Susceptibility
Genetic and environmental factors play an important role in the overall susceptibility to a prototype autoimmune disease, SLE and pathophysiology between the affected individuals. SLE has a complex genetic basis that includes many susceptible loci. PTPN22 has been reported as one of the susceptible loci where an SNP 1858C/T in the PTPN22 gene has been found to be associated. SLE patients are susceptible to common and opportunistic infections, which contributes significantly to morbidity and mortality in endemic areas. In many populations, infection is found to be the leading cause of death in SLE. Evidence suggests that in most of the cases opportunistic infections such as candidiasis, cryptococcal meningitis and tuberculosis (TB) leads to mortality. [33],[34],[35],[36] It was reported that the autoimmune disease risk allele of PTPN22 is associated with skewing of the serum cytokine profiles toward higher IFN alpha activity and lower TNF alpha levels in vivo in patients with SLE. This serum cytokine pattern may be relevant in other autoimmune diseases associated with the PTPN22 risk allele. Although, in general, PTPN22 appears to be coupled with the collection of autoimmune diseases that are typically characterized by circulating autoantibodies, the role of PTPN22 in autoantibody response may not necessarily be intrinsic to B cells but rather a consequence of altered T cell help.
An increased susceptibility to infections is due to an abnormal immune response and immunosuppressive therapy used in SLE. Several studies suggest that there is an increasing prevalence of TB infection, especially in the endemic parts of the world such as part of Asia, sub-Saharan Africa and central Europe. A possible role of prior TB infection in precipitating SLE in genetically predisposed patients had been reported. The PTPN22 locus is also found to be responsible for the development of pulmonary TB in certain populations. The PTPN22 1858C/T gene locus will be ideal to look for SLE susceptibility to TB in the Indian population. As Mycobacterium tuberculosis is a strong immunogen, and its product is used extensively as an adjuvant, there is the distinct possibility that in genetically predisposed individuals TB infection may precipitate in SLE. [37],[38],[39]
Lamsyah et al., 2003, had reported on the role for PTPN22 G788A (R263Q) in susceptibility to infectious diseases such as TB. The Q263 enzyme is a loss-of-function variant that is associated with reduced risk of lupus. [35] The association of the two PTPN22 gene variants [R620W(C1878T) and R263Q(G788A)] was found to be relevant in the opposite direction than the ones observed with autoimmunity. The protective effect of the T1858 allele against TB might contribute to the positive selective selection at this locus, which might explain its high frequency in selected populations, despite its role in increasing the risk of autoimmunity. PTPN22 seems to influence the susceptibility to pulmonary TB. The role of PTPN22 in TB and other infectious diseases warrants further investigation. The protective effects of the gain-of-function W620 PTPN22 variant in TB suggest that PTPN22 could be a target for novel pharmacological approaches to the therapy of TB.
A candidate biomarker approach is based on the study of known factors that are thought to be involved in disease pathogenesis to identify biomarkers. [ 40],[41] Lack of validated biomarkers for disease activity has been a barrier to drug discovery for the treatment of autoimmune diseases. There is a need to explore the genetic association of PTPN22 1858C/T gene polymorphism with SLE susceptibility to TB in the diverse populations of India. If the PTPN22- Trp620 gain-of-function phenotype has a pathogenic role in human autoimmunity, a specific small molecular inhibitor could be useful to prevent the emergence of autoreactive T-cells. Such a drug could be of broader value for the treatment of autoimmune diseases. [42] Gene therapy is an attractive alternative for systemic protein delivery systems. Gene therapy can be considered as an alternative therapeutic approach to replace the function of the mutant or aberrant gene. This approach of synthesizing therapeutic protein in vivo allows minimizing possible side-effects. Local delivery of PTPN22 gene alone or in association with other SLE-related genes in SLE patients can turn out to become a possible therapeutic approach with several potential advantages over systemic forms of targeted therapy. Several strategies for successful delivery of DNA are available and new techniques are constantly emerging. New vectors (viral and non-viral) continue to become the most promising treatments for a number of autoimmune diseases. However, additional safety studies involving pharmacokinetics, biodistribution and toxicity will need to be accurately evaluated in experimental animal models. [43]
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Ahh, shabby chic. It may remind some of us of the halcyon days of the 90's when old side tables were being dressed in pastels and popping up in every rom-com and sitcom imaginable. (Think Meg Ryan's apartment in You've Got Mail, or Monica and Rachel's apartment in Friends). Or maybe you know it from marathons of From Trash to Treasure on HGTV. Either way, shabby chic is an enduring design style to this day, celebrated for its approachability and ability to perfectly blend old with new.
"Shabby chic" was first coined in the 80's by Min Hogg, editor of World of Interiors magazine. Hogg called shabby chic the antidote to the over-the-top opulence of the 80's, defining it as "a catch all for comfortable, cosy, worn, informal interiors." Shabby chic was soft pastels and worn wood in a world of black lacquered tables and serious dark oak. As result, many associate shabby chic with feelings of comfort and hominess. So it's no surprise that shabby chic endures today.
Because the whole point is to look a bit worn-in and cozy, shabby chic is never out of date. But what else is there to love?
We love shabby chic because it creates a welcoming space--it's the idea that no piece of furniture is so precious that it can't be lived in. Because shabby chic pieces are typically antique (or antique-looking) pieces that have been painted to fit a specific room, they convey an air of sophistication without being pretentious.
Shabby chic furniture is there to be used, rather than put on display like you might an antique. It's a relaxed, low maintenance elegance, or what Chris Martin, director at Lassco reclamation yard in London calls a "whiff of faded grandeur." If you're looking to create a space that's refined but not uptight, shabby chic is the way to go.
Making an old desk new with a little bit of blue.
Fun fact about buying vintage? It's good for the earth. The craftsmanship and quality of vintage furniture is typically higher than new furniture today (sorry, Ikea). That means that it'll probably last you a lot longer, even if it was mass produced in the time it was made. That also means that you're less likely to toss this furniture in the landfill, making your purchase automatically eco-friendly.
Plus, the way that we make and buy furniture has undergone a massive transformation over the past century. Today, buying hand-crafted furniture is often prohibitively expensive and affordable, pre-fabricated furniture from big box stores often has a short lifespan and is devoid of personality. One of the best things about going shabby chic is that you can re-paint or re-style a piece of furniture as many times as you'd like, meaning less waste from always buying furniture new.
That leads us to our favorite thing about shabby chic: you can make your furniture "new" again and again. With a few hours and a can of paint, anyone can transform an antique or vintage piece of furniture into shabby chic.
It's a great intro to DIY (Do It Yourself) projects because there's no pressure to make it perfect since you're not attempting a perfect restoration. There's lots of great tutorials to make your furniture unique and perfectly suited to any room. And, because shabby chic furniture is intentionally dilapidated, it's totally kid friendly and easy to maintain. Added bonus: if you re-design the room you can just re-paint it!
Unlike an antique shop, Loveseat prices our furniture so you have the freedom to go shabby chic without a massive price tag. We want to make your furniture shopping experience approachable and affordable, so if you're on the market for some pre-loved furniture give us a shout or take a look at our selection for some inspiration.


Published: Feb 20, 2018 at 12:03 p.m.
Updated: Feb 20, 2018 at 12:16 p.m.
Sending people halfway around the world to lead off their sportscast with NHL and NBA highlights seems like a bit of a waste.
But that's what's happening on SportsCentre with Jay and Dan every weekday morning on TSN during the Winter Olympics in Pyeongchang.
Jay Onrait and Dan O'Toole have been back at the Toronto-based sports channel since September, following a close to four-year foray in the States. Fox Sports 1 poached them in a bid to challenge ESPN, the entrenched leader in sports TV down there.
After Fox Sports had a change in leadership and direction last year, the Jay and Dan brand was welcomed back home. Given the multi-channel nature of TSN now, the pair's mix of highlights and humour is offered as an alternative to a more staid version of what happened in the sports world any given day.
But they seem to be flying under the radar at these Games. If there's been much promotion of their assignment, I've missed it. On the other hand, it would probably be different if CTV, TSN's big network sibling, was the main Olympics rights holder for Canada. But that's CBC, which does dole out a few hours of coverage to TSN and Sportsnet.
Jay and Dan would have to do some pretty outstanding work to compete. Well, based on a couple samplings, the first block of the show is pretty much hockey highlights from North America, delivered from a rooftop set, with our hosts decked out in winter jackets and mountain scenery as a backdrop. The second segment has bona fide Olympics action.
But Jay and Dan fans can get that anywhere. It's not until the back half of the show that you find The Adventures of Jay and Dan in South Korea, a travelogue-type segment that has featured a trip to the demilitarized zone and a street that has nothing but coffee shops. There's also a regular bit that has O'Toole attempting to taste-test various unorthodox Korean delicacies. Better are casual on-set interviews with Canadian Olympians like medal-winning lugers Sam Edney and Alex Gough.
But aside from accumulating air miles, it's hard to see what the overall goal was.
There's a regular Jay and Dan segment called Ya Blew It! Whoever drew up the coverage plan for them in South Korea might be in the running for a future episode.


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San Jose, CA to become largest US city to ban natural gas
Katie Pyzyk Contributor
Will Buckner, Flickr
San Jose, CA Mayor Sam Liccardo and other city council members approved a proposal to prohibit natural gas infrastructure from being installed in many new residential buildings. The measure covers single family homes, accessory dwelling units and low-rise multi-family buildings.
The ordinance would require all new multi-family buildings to have 70% electric vehicle (EV) capable parking spaces, at least 20% EV ready spaces and at least 10% EV supply equipment spaces.
A final ordinance is expected to be approved in October, going into effect on January 1. The council's intention is to expand the ban to include more buildings, and it has requested check-ins from city staff over the next several months with recommendations for the expansion, a mayor's office spokesperson told Smart Cities Dive. They are also examining offsetting the cost of solar and battery storage installations in affordable housing.
San Jose's ban comes just after Berkeley, CA passed a natural gas ban that will also take effect on January 1. San Jose is the largest city to advance this type of ordinance. It aims to reduce emissions from buildings, which are considered the largest emissions producers along with transportation.
Other U.S. cities also are pushing for greater building electrification to get away from fossil fuel use. Seattle Mayor Jenny Durkan proposed a tax on heating oil providers to help 3,000 homes transition from oil to electric heat. This spring, San Francisco Mayor London Breed proposed a plan to transition buildings over 50,000 square feet to 100% renewable energy by 2030. That occurred just after Chicago became the largest U.S. city to commit to 100% renewable energy use by 2035.
A number of climate and environmental advocacy groups, including the Sierra Club, are in favor of San Jose's move.
"As gas companies and their shady front groups continue to use sketchy tactics to hold communities back from realizing their clean energy realities, leaders in over 50 California cities are moving ahead on similar strategies to end their reliance on gas in their homes and businesses," said Matt Gough, senior campaign representative for the Sierra Club's My Generation campaign.
But opponents of natural gas bans warn that these moves could harm citizens because natural gas provides a lower priced, more efficient type of energy.
"We are saddened and disappointed that several city councils are considering action to ban the use of natural gas ... Unfortunately, across the country, there is a growing effort to move communities to a single source all-electric model, eliminating clean, resilient natural gas. These 'all eggs in one basket' policy proposals are shortsighted, untested and eliminate the ability for consumers to decide what is best for their families," said Dave Schryver, executive vice president of the American Public Gas Association, in a statement.
San Jose leaders contend the ban will provide consumers cost savings in the long run, in addition to improving their health and the environment.
The natural gas ban advanced in part from funding from the Bloomberg Philanthropies' American Cities Climate Challenge, the mayor's office spokesperson said. It was the largest environmental grant San Jose had ever received. The Natural Resources Defense Council also worked with San Jose on its electrification plan.
Antidote to Trump: San José Mayor and Councilmembers Call for City to Become the Largest in the Nation to Require Construction of Electric Buildings City of San Jose
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NYC's new gas ban highlights market growth needs for building electrification
Outgoing Mayor Bill de Blasio signed the climate legislation in his final days in office, but work to expand awareness, market development and worker training remains.
By Maria Rachal • Dec. 22, 2021
"Jogger Crosses Empty New York City Street During COVID19 Quarantine" by Anthony Quintano is licensed under CC BY 2.0
How the pandemic has shaped driver and pedestrian behavior
The past year has seen drastic changes to driver behavior and commuting patterns, ushering in an era of high traffic and pedestrian deaths.
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redpajama_set_name: RedPajamaCommonCrawl


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the men's team my second family. When my dad helped form the FPU women's team in 1998 that family grew even bigger. I was always at FPU training sessions and went to almost every game. Even my mom got into coaching for a while! She didn't know anything about soccer before meeting my dad. It was contagious.
In order to have booked my acting jobs which included a national commercial for Sprint with David Beckham; I needed the fundamental skills expected of a soccer player.
Click here to read my whole story!


text:
BSA Study Groups
Join the BSA
MedSoc Groups
Phil Strong Memorial Prize
Foundation for the Sociology of Health and Illness Book Prize
BSA >> Groups >> Medical Sociology Groups >> Medical Sociology (MedSoc) Study Group >> Prizes >> Phil Strong Memorial Prize
We are pleased to announce the Phil Strong Memorial Prize for the Academic year 2018-19. The prize was established in memory of Phil Strong (1945-1995) one of the post-war generation of sociologists who influenced the development of medical sociology in the UK, and it is anticipated that there will be one prize to the value of £1200 awarded this year. The purpose of the prize is to contribute to the advancement of medical sociology by supporting postgraduate research in medical sociology.
Phil's work combined rigorous empirical analysis with sociological imagination. He was one of the foremost exponents of Goffman's ideas, but he did not confine himself to interactionism, or indeed to sociology, in his reading or thinking which drew on philosophy, political science and literature. His empirical research included important studies of the clinical encounter, NHS reforms, and the social history of AIDS. In memory of his contribution as an essayist, researcher and teacher this prize has been established to support postgraduate research in medical sociology.
Previous Winners of the Phil Strong Memorial Prize
Read Philip M Strong (1945-1995): an appreciation of an essayist by Michael Bloor
We are delighted to announce Maria Jesus Vega Salas as the 2018 Phil Strong Memorial Prize winner.
To enter, complete the Application Form and return as an email attachment to the BSA Office. Alternatively, you can post your application to the address on the Application Form.
Applications must be submitted to arrive no later than Friday, 16 August 2019. Incomplete applications and applications received after this date will not be considered.
Applicants must show that they are low waged or unwaged and not receiving a full or part time research studentship that is intended to cover maintenance and research expenses for the duration of study, that they are working in the field of Medical Sociology and that they are registered for a higher degree at a British University or other recognised British research institution, with a named supervisor who is a member of the BSA.
The announcement of the winner for this year's prize will be made at the Medical Sociology Study Group's AGM during their Annual Conference.
Selection criteria for the Phil Strong Prize
A selection panel comprising the co-convenors and early-careers representatives of the Medical Sociology committee will decide on the winner using the following criteria:
Relevance- is the relevance of the applicant's research to medical sociology made clear?
Purpose - is the use of the proposed prize activity for the applicant's research made clear?
Conditions of the award of the Phil Strong Prize
The money will be paid by BACS transfer to the sponsoring institution. The sponsoring institution is responsible for administering and accounting for the money and making such information available to the Committee on request.
Departments that do not comply with the conditions listed above will not be allowed to enter students for the prize in the following five years.
Students receiving the Phil Strong prize must produce a short report (approximately 1000 words) on how the money has been used. This should include (1) a brief overview of their doctoral research including the background, aims and objectives, methods and progress to date including a summary of any analysis or conclusions (2) an account of the activities supported by the Phil Strong Memorial Prize, including any reflections on how this enhanced the study or the recipients' sociological development. This should be submitted to the convenors of the BSA Medical Sociology Study Group within three months of the completion date specified in the student's application.
The recipient should keep the convenors of the Medical Sociology Committee informed should there be any problems associated with the use of the money.
The prize money may not be used for any purpose other than that for which it is granted. Should the money not be used within one year of the time from which was awarded, it shall be returned to the Medical Sociology Group.
These conditions may be varied by the Medical Sociology Committee, subject to the approval of the AGM, to optimise the outcome of the Phil Strong Memorial Prizes and enhance the good name of Medical Sociology.
*PLEASE NOTE*
The Phil Strong Prize Money may not be used for:
The material production of a thesis (e.g. photocopying and binding). The BSA has a support fund to which students can apply for this;
Courses which should be offered by the Department/Unit as part of normal provision for postgraduate or undergraduate students (e.g. standard courses in research methods);
Return fares for an international student, registered in Britain, to return home. Exceptions may be made if there is strong evidence of how this would advance the study;
Materials and equipment such as books, computers (including access to the internet) and recording equipment which should properly be supplied by the sponsoring institution; and
Any purpose which is unlawful.
2017 - Khalid Al-Muhandis
2016 - No applications received
2015 - Elizabeth Sutton
2014 - Rose Closson
2013 - Jeremy Booth
2012 - Timothy Banks
2011 - Agato Pacho, Ghada Ibrahim and Lucy Moore
2010 - Rampaul Chamba
2009 - Lynn Tang
2008 - Marion Judd
2007 - Sonali Johnson
2006 - Kerry Jones
2005 - Wendy Martin


What are Novelum USA ceilings made of?
What kind of accessories can be mounted on the ceilings?
Can it be applied to a wall?
What is the delivery time for Stretch ceilings?
Can it be installed in public spaces?
Novelum USA ceilings are made from a special PVC film with unique caracteristics.
The film is applied to stretch and is held in place by profiles specially designed on purpose.
Novelum USA ceilings are very resistant. They are able to support heavy charge ( as a water damage).
The ceiling will be deformed but will return to its initial position without any sagging or loss of shine, colour, texture or form.
The ceiling's membrane is surrounded by a semi rigid PVC profiles forming as a hook to be clipped.
This profile is welded by High Frequency. Rails are fixed ( stapled or screwed)to the existing walls or ceiling. We can form shapes as waves.
Every type of accessory available in the market at present can be installed with a stretch ceiling.
That includes spot or hanging lights, air conditioning, extracting or ventilation grids, sprinklers, fire detectors or anything else.
Due to its anti bacterial texture, in PVC the stretch ceilings can be washed as many times as necessary, keeping a perfect hygienic surface.
They can be washed with water and soap.
Yes! One of Novelum USA rails can be installed on walls.
Once the technician has taken measurement on the job site the stretch ceiling could be placed in the following three weeks.
The stretch ceilings are A1 fire tested.
Copyright © 2012 BlueVed. All rights reserved.


It may seem like there's still a lot of snow in the mountains, but we're already planning for the summer season! That includes thinking about the Trail Ambassador program on Scotchman Peak.
If you've hiked Scotchman Peak, you know all about the mountain goats that call the peak home. And you probably know that they can be a bit naughty. From licking sweat off hikers to full on stealing trekking polls (because they have sweat on them too). These goats are on a mission to find salt.
Luckily, mother nature has provided them with plenty of options already. Unluckily, they've decided hikers (and the things they leave behind) are an easier target. Enter the Trail Ambassador program.
Volunteer Trail Ambassadors hike Scotchman Peak during the summer and early fall to talk with folks about safety in mountain goat habitat. Keeping a distance (100' or more) from the fluffy critters is not just to keep people safe, it's to keep the goats safe too. Becoming dependent on humans for salt can hurt their ability to survive in their natural habitat. If they become too aggressive, desperate measures may be needed.
"There is a fine line between civilization and wilderness." Trail Ambassador Tracie Babor enjoys keeping the wild wild.
Tracie Babor, über Ambassador from 2018, believes in the benefits of the program for the volunteers as well. "It has been a fantastic responsibility to coexist with nature, while nurturing and keeping the wild wild. The coexistence has been a renewal of the mind and body. And an honor that I have fully embraced!" And Tracie would know. She hiked Scotchman Peak three times in 2018 as Trail Ambassador.
If hiking Scotchman Peak is on your to-do list this year, sign-up to be a Trail Ambassador and do it with a greater purpose. Not to mention an excuse to stop along the trail to catch your breath while talking with other hikers.
Remember to put June 8 on your calendar for Trail Ambassador training!
Baby goats cover photo by Bryan Tollbom.


Co-hosts Sandra Oh and Andy Samberg at the rollout of the Red Carpet for the Golden Globe Awards 2019 at the Beverly Hilton Hotel in Beverly Hills, CA. January 3, 2019.
There are plenty of big questions about tonight's Golden Globe Awards ceremony: Can A Star is Born sweep all five of its big-category nominations, or will it get sha-la-la-la-shafted? Which award will be presented by Rami Malek's stunt-teeth from Bohemian Rhapsody? And, when it comes to all-time great Globes reaction-shot memes, will any celeb be able to carry Tommy Lee Jones' fire?
The red carpet arrivals—in which eerily over-smiling, Muppet-like creatures awkwardly ask famous people about international events—will begin with E! Countdown to the Red Carpet: The 2019 Golden Globe Awards. That special airs Sunday, starting at 1pm Pacific (4pm Eastern), and you can watch it on E!, or on the network's smartphone app. If you can only find time for a few red carpet looks, or even slayalicious lewks, there are multiple specials airing closer to the show's starting time: E!'s Live From the Red Carpet—also on the network's smartphone app—starts at 3pm Pacific (6pm Eastern). Meanwhile, NBC's own arrivals show starts at 4pm Pacific (7pm Eastern) on the website, the network's app, and its Facebook page.
Once the whole thing is over—hopefully by 8pm Pacific (11pm Eastern)—you can then tune into E!'s Busy Tonight Live: Golden Globes After Party, hosted by Busy Philipps, which will also be on E! and its smartphone app.
Of course, one of the best ways to watch any awards show is to keep up on Twitter, where breakout moments and weirdo red-carpet comments are immediately consumed, archived, and memed into awards-show infamy. This year, the show's highlights will also be broadcast on Snapchat Discover about an hour after the show begins. That's a lot of GlobesTent(™) to consume in one night, but we know you can do it. Have fun at your at-home awards ceremony, and stay golden!


text:
CBS & Big Ten Conference reach 7-year football & basketball deal
BALTIMORE — Beginning next year, all Big Ten Conference football and basketball games will be aired on CBS and streamed live on Paramount+ under a new broadcasting agreement.
CBS on Thursday announced a seven-year, multi-platform rights agreement between the network and conference for both sports, which begins in 2023 and runs through the 2029-2030 season.
College basketball fans are accustomed to seeing the Terps play on WJZ, but the football games are a new reason to tune in.
In a statement, CBS Sports Chairman Sean McManus said the network was thrilled to build on the existing relationship it has had with the conference for more than three decades.
"The combination of CBS Sports' proven record in elevating college conferences to new heights, our standard of excellence and the…
CBS Baltimore Staff
Tags: 7year basketball big CBS Conference deal football reach Ten
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Q: Angularjs Selectbox with remote data and no empty value I have a common problem with selectboxes in angularjs, when I retrieve the options and the model from REST api.
This is my html which is inside a ng-repeat:
<select class="form-control"
    name="{{ field.name }}"
    ng-model="data[field.name]"
    ng-options="key as value for (key, value) in field.options">
</select>

In the controller I retrieve both - the $scope.field value and the $scope.data value from a (REST) service. The data basically looks like this:
data = {
    'selectfield' => 2
};
field = {
    'name' => 'selectfield',
    'options' => {
        '1': 'Option 1',
        '2': 'Option 2'
    }
};

The problem: I get an empty option for this selectbox and this empty value is selected, even if the data.selectfield has another value. What can I do?

A: Your select is bound to the value of data[field.name]. So it default value will be the value of data[field.name] which is selectfield. (And not its value)
You should change the expression in ng-model="data[field.name]" to the variable's name you would like to bound the select.
For example in your case if data is also a $scope variable:
ng-model="data.selectfield"

redpajama_set_name: RedPajamaStackExchange


An area of low pressure is just off shore spewing lines of showers across the state. This rain will increase heading into tomorrow before tapering off tomorrow night and into Monday.
It looks like Tuesday, Wednesday and Thursday of next week will be mostly dry as a ridge of high pressure builds into the mix. Temperatures will get close to 70 degrees by mid-week. Another low will drag a chance of scattered rain back into the forecast by Friday with highs in the lower 60s.


Gas Plate heat exchanger,热交换芯体,Air heat recovery Core-Xiamen AIR-ERV Technology Co. Ltd.
Xiamen Air-ERV Technology Co., Ltd.
Cross flow heat exchanger core is made of antiseptic hydrophilic/epoxy coating aluminum foil and galvanized sheet cover.The air is forced to crossover through the heat exchanger core, two airstreams never come into direct contact,avoid the transfer of any smell and moisture. It is usually being used for recovering enegy at residential, commercial and wind-power industry ventilation systems.
Counter flow heat exchanger core i$ made of antiseptic hydrophilic/epoxy coating aluminum foil and galvanized sheet cover.The air is forced to counter through the heat exchanger core,two airstreams never come into direct contact, avoid the transfer of any smell andmoisture.It is usually being used for recovering enegy at industrial ventilation system, such as: base station/outdoor cabinet ventilator and so on.
Heat exchanger core is made of fireproof and antibacterial fibrous paper and ABS framework,the air is forced to crossover through the heat exchanger core, two airstreams never come Into direct contact, avoid the transfer of any smell and moisture. It is usually being used for residential ventilation system, in order to recover the energy and moisture.


Events, tradeshows and conventions are often the most tangible affirmation of value for user communities and technology-focused associations. They can be the organization's largest source of revenue, provide attendees with education, networking opportunities, and new product innovations, and help member or affiliate companies achieve their sales and marketing objectives. Our client organizations benefit from SmithBucklin's experience as one of the most respected and engaged participants in the conference industry. Our expert teams apply leading practices to deliver powerful results through the creation and management of educational programming, conference design, business model development, participant marketing, site selection, registration, technology, logistics, attendee experience, and tradeshow and sponsorship sales and fulfillment.


Nishant is an Android Engineer and open source enthusiast who spends his time doodling when not hacking on Android. He is a caffeine-dependent life-form and can be found either talking about android libraries or advocating that coffee is the elixir of life at community gatherings.
15 Github: How to embed a gist into README.md?
7 How do I kill all active tasks/apps using ADB?


As we are in our Summer Part Deux, is it possible to say that it is still "ice cream season"? To someone that would much rather be sweating hot than freezing cold, it is still warm enough to go out of my way for Red Mango. However, although Fall is shortly upon us, Brooklyn Farmacy and Soda Fountain is a reason to go out of your way for ice cream no matter what the temperature is outside.
Brooklyn Farmacy is a family owned ice cream destination located in a beautifully restored 1920's pharmacy offering an extensive menu of anything goes creations of ice cream treats. They offer sundaes with various bases such as buttermilk biscuits or different pies, custom made Whoopie pies with the ice cream flavor of your choice. They offer their rendition of The Elvis with candied bacon bits and a pickle and of course homemade egg creams (yes Mom, we can go) and floats again with you choice of ice cream.
Although, normally I'd be hesitant to admit that I stuck with something "simple" or "basic", I was far from dissatisfied and quite happy that I chose to have 2 scoops topped with bananas and a cone on the side. My 2 flavors were pumpkin ('tis the season) and coffee. This ice cream is so fresh and made from true ingredients – I was able to taste the actual pumpkin and the actual coffee used. It was delicious and satisfying!
Brooklyn Farmacy also serves old school soda fountain savories. Whether you are in the neighbor or have the time to make a trip to Carrol Gardens, I SO recommend stopping in for some food and some dessert – any time of the year.
This entry was posted in hungry? and tagged Brooklyn Farmacy & Soda Fountain, egg creams, floats, ice cream, sundaes, Whoopie pies. Bookmark the permalink.


text:
Arthoniomyces E.A. Thomas ex Ciferri & Tomaselli, 1953
Fungi (Kingdom)
Ascomycota (Phylum)
Arthoniomycetes (Class)
Arthoniales (Order)
Arthoniaceae (Family)
Arthoniomyces (Genus)
Arthonia E. Acharius, 1806
Arthoniaceae Reichenb. ex Reichenb., 1841
Taxonomic remark A homotypic synonym of Arthonia Acharius 1806 according to Index Nominum Genericorum.
Taxonomic remark A homotypic synonym of Arthonia Acharius 1806 according to Index Nominum Genericorum. [details]
IRMNG (2018). Arthoniomyces E.A. Thomas ex Ciferri & Tomaselli, 1953. Accessed at: http://www.irmng.org/aphia.php?p=taxdetails&id=1067797 on 2019-07-19
basis of record Index Fungorum [details]
basis of record SN2000/Kirk et al., 2001 [details]
basis of record Farr, E. R.; Zijlstra, G. (eds). (1996-current). Index Nominum Genericorum (ING). A compilation of generic names published for organisms covered by the ICN: International Code of Nomenclature for Algae, Fungi, and Plants. [previously: organisms covered by the International Code for Botanical Nomenclature]. Web publication, available at http://botany.si.edu/ing/ (accessed August 2007). [details]
source of synonymy Index Fungorum [details]
verified source for family Index Fungorum (May 2009) [details]
verified source for genus Farr, E. R.; Zijlstra, G. (eds). (1996-current). Index Nominum Genericorum (ING). A compilation of generic names published for organisms covered by the ICN: International Code of Nomenclature for Algae, Fungi, and Plants. [previously: organisms covered by the International Code for Botanical Nomenclature]. Web publication, available at http://botany.si.edu/ing/ (accessed August 2007). [details]
extant flag source Index Fungorum [details]
habitat flag source same as current name [details]


Then Zapier provides an URL. Copy this URL to enter it in your Clustaar app, to allow Clustaar to send the information needed to Zapier.
Zapier integration action is on the action panel of your step, in the "Integrations" part.
"Define your variables": to define the variables you want to be sent to Zapier.
- Variable value: The value taken by your variable. It can be a session value or a user attribute.
- URL: URL provided by Zapier during Webhook configuration - mandatory.
Here you can describe your Zap, to have a good visibility on each Zap purpose in case you have several integrations with Zapier in your bot.
Once this is done, you can click on "Confirm" to save your configuration parameters. The action appears in the step panel with the description and variables displayed.
You then have to come back on Zapier to finish setting up your Zap. All you need to do at this point is to set your "Action App", which will be the app receiving the information from Clustaar. You can choose any app among those proposed by Zapier.
For this example, we will create a new Google Sheets row for each user with the information recovered during his conversation with the bot (name and email).
6. Last but not least, do not forget to put your Zap "ON"!


The Oregon Shakespeare Festival will open the world premiere of Lisa Loomer's Roe on April 24 in the Angus Bowmer Theatre. Preview performances are April 20, 22 and 23.
Directed by OSF Artistic Director Bill Rauch, Roe is about the two women at the heart of Roe v. Wade: lawyer Sarah Weddington, who was only 26 when she argued the case before the U.S. Supreme Court, and plaintiff Norma McCorvey, the hard-drinking, wild-tempered bartender who became "Roe" after seeking to end an unwanted pregnancy. That they won the landmark 1973 case legalizing abortion is widely known; how different their lives were after the case-and how those divergent journeys reflect the subsequent polarization of American culture-is far less familiar.
Roe, a co-production with Arena Stage and Berkeley Repertory Theatre,is the latest play to emerge from American Revolutions: The United States History Cycle, OSF's commissioning program examining key moments of change in U.S. history, such as Lyndon Baines Johnson's presidency in Robert Schenkkan's Tony Award-winning All the Way and The Great Society, and the "de-industrial revolution" of the 1990s in Lynn Nottage's Blackburn Prize-winning Sweat.
"We produced All the Way in 2012, a presidential election year, and to be doing another American Revolutions play four years later during another presidential election feels vitally important to me," Rauch said. "Whoever the final candidates are for the major parties, there is no doubt the issue of abortion is going to be more in the foreground than it has been in years. To look at what led up to 1973 and what has happened since feels like something a theatre company should be doing in 2016."
Compelling, entertaining, thought-provoking, humorous and moving, Roe is not a polemic, but instead an examination of the difficult choices women make and the passion each side has for its cause.
"The characters in Roe really span from very decidedly pro-choice to very decidedly pro-life, and there are even characters who shift their views over the course of the story," Rauch said. "What Lisa's done that's so remarkable is she really reveals the humanity of every character. So wherever someone sits in their own heart on abortion, I think Lisa's given space for everybody to come and experience the story."
"I see theatre as people sitting together in the dark to look at the human condition," Loomer said in OSF's Prologue magazine. "Perhaps to consider a question together. If we are really considering the questions that are evoked by Roe v. Wade, don't we have to hear from both sides? I don't kid myself that a play will change minds. It happens, but very rarely. But if we can open our minds enough to even consider a position that is different from the one we brought into the theatre-that is the beginning of compassion."
OSF previously produced Loomer's Distracted in 2007; Loomer's other plays include The Waiting Room, Living Out (directed by Rauch at the Mark Taper Forum), Bocón! and Café Vida. She has been awarded both the American Theatre Critics Award and the Jane Chambers Playwriting Award twice, the Kennedy Center Fund for New American Plays Award, the Lurie Foundation Award, the Edgerton Foundation New American Plays Award, the Imagen Foundation Award and the Susan Smith Blackburn Prize, among others.
Coinciding with the run of Roe is the second year of the Living Ideas: Art and Community Dialogue Series, a humanities program that seeks to forge connections between individuals and communities through collaborative programming driven by the works on the Festival's stages. This year, Living Ideas will present a series of events that frame Roe v. Wade through the lens of history (May 14-15), agency (July 15-16) and advocacy (August 19-20).
The cast of Roe features Sarah Jane Agnew as Sarah Weddington, Sara Bruner as Norma McCorvey, Gina Daniels as Aileen/Barbara/Uma/Third Pregnant Woman/Ensemble, Susan Lynskey as Linda Coffee/Judy/First Pregnant Woman/Peggy/Ensemble, Amy Newman as Helen/Second Pregnant Woman/Ronda/Ensemble, Kate Mulligan as Molly/Mary/Ensemble, Catherine Castellanos as Ofelia/Connie Gonzalez/Ensemble, Barret O'Brien as Henry McClusky/Robert Flowers/Abortion Doctor/Ensemble, Jeffrey King as Ron Weddington/Jay Floyd/ Flip Benham/Ensemble, Richard Elmore as Justice Blackmun/Dr. Kennedy/Ensemble, Zoe Bishop as Justice Blackmun/ Dr. Kennedy/Ensemble and Nemuna Ceesay as Roxanne.
Scenic design is by Rachel Hauck, costumes by Raquel Barreto, lighting by Jane Cox, composition and sound by Paul James Prendergast and video by Wendall K. Harrington. Tom Bryant is dramaturg, Rebecca Clark Carey is voice and text director, U. Jonathan Toppo is fight director, Sarah Beata DeLong is associate costume designer, Lavina Jadhwani is Phil Killian Directing Fellow and Jeremy Eisen is stage manager.
Roe's Lead Sponsor is the The Goatie Foundation, and the play is the recipient of an Edgerton Foundation New Play Award. OSF also gratefully acknowledges the support of Production Sponsor The Paul G. Allen Family Foundation, and Production Partners Andrew and Brenda Birrell, Nancy and Donald de Brier, Carol Streeter and Harold Goldstein, Thomas Castle and Pamela Howard, Claudette and George Paige, and Betty and Jack Schafer.
The production runs April 20 through October 29, 2016.


A house of prayer for all nations and we are here for all people to experience Christian community as God's people, to be filled with God's presence and to live for God's purposes together.
We began in 2008 as a "Minneapolis" service out of Bethel Christian Fellowship in St. Paul. We soon realized that we were called to be a church, not a third-service or campus and that Bethel was called to help plant churches, not campuses. Since making that shift 10 years ago, our churches have now grown to seven churches with people from over thirty different nations worshipping together each week! Together we are the All Nations Family of Churches here in the Twin Cities and form part of the international family of ministers and ministries called the Fellowship of Christian Assemblies.
Every Sunday at 5 PM we share a free dinner together followed by a time of worship at our location in North East Minneapolis.
We also meet in community groups in neighborhoods throughout the week as we actively seek to love God and our neighbors together.
For All People: We are always looking to create opportunities for everyone to begin with God no matter their background or stage of life.
To Be God's People: We seek to live out what it means to be God's family by developing lasting relationships with others.
With God's Presence: We desire to welcome and host the presence of God as we passionately pursue Him in prayer and worship.
For God's Purposes: We want to join with God in His purposes to Redeem, Reconcile, Renew, and Restore individuals, families, communities, and nations.


MONTREAL, QUEBEC and SARASOTA, FLORIDA--(Marketwired - Nov. 13, 2013) - Intertape Polymer Group Inc. (TSX:ITP) ("Intertape" or the "Company") today released results for the third quarter ended September 30, 2013. All amounts are denominated in US dollars unless otherwise indicated and all percentages are calculated on unrounded numbers.
"We are pleased with the increase in gross margin over last year which reflects manufacturing cost reductions and an increase in the spread between raw material costs and selling prices. For 2014, we expect gross margin to be between 20% and 22%. This range assumes temporary costs associated with the relocation of our South Carolina manufacturing operation offset by continued success with gross margin expansion initiatives," stated Intertape President and Chief Executive Officer, Greg Yull.
"The increase in revenue reflects an increase in selling prices, including the impact of product mix, which was offset by a decrease in sales volume reflecting our decision to reduce sales of low-margin products.
"During the quarter, the Company redeemed the remaining $18.7 million of high interest-bearing Notes. The lower average cost of debt combined with the reduction in debt significantly reduced interest expense year-to-date," concluded Mr. Yull.
On November 12, 2013 the Board of Directors declared a dividend of $0.08 per common share payable on December 30, 2013 to shareholders of record at the close of business December 16, 2013. These dividends will be designated by the Company as "eligible dividends" as defined in Subsection 89(1) of the Income Tax Act (Canada).
The Company's revenue for the third quarter of 2013 was $199.9 million, an increase of 0.7% compared to $198.5 million for the third quarter of 2012. Revenue was higher in the third quarter of 2013 compared to the third quarter of 2012 primarily due to an increase in selling prices, including the impact of product mix, partially offset by a decrease in sales volume. The decrease in sales volume of approximately 3% when compared to the third quarter of 2012 was primarily due to the progress the Company made in reducing sales of low-margin products in the second half of 2012 partially offset by increased sales of new products. Selling prices, including the impact of product mix, increased approximately 4% in the third quarter of 2013 compared to the third quarter of 2012. The increase in selling prices was primarily due to higher selling prices of equivalent units and a shift in the mix of products sold.
The Company's revenue for the third quarter of 2013 increased 3.3% sequentially compared to $193.5 million for the second quarter of 2013. Revenue increased in the third quarter of 2013 compared to the second quarter of 2013 primarily due to higher sales volume partially offset by a decrease in selling prices, including the impact of product mix. The increase in sales volume of approximately 5% was primarily due to increased demand for tape and film product lines. The Company believes that some of the increased demand for film products in the third quarter of 2013 was due to customers pre-buying in response to an announcement of a price increase to take effect on orders placed on or after September 30, 2013. The Company also believes that the second quarter of 2013 volume was lower partially due to customers pre-buying both tape and film products during the first quarter of 2013 in advance of price increases that took effect in the first quarter of 2013. Selling prices, including the impact of product mix, decreased approximately 2% in the third quarter of 2013 compared to the second quarter of 2013. The decrease in selling prices was primarily due to a shift in the mix of products sold and lower selling prices of equivalent units.
Gross profit totalled $40.0 million in the third quarter of 2013, an increase of 14.3% from $35.0 million in the third quarter of 2012 and a decrease of 5.4% from $42.3 million in the second quarter of 2013. Gross margin was 20.0%, 17.6% and 21.8% in the third quarter of 2013, in the third quarter of 2012 and in the second quarter of 2013, respectively.
When compared to the third quarter of 2012, gross profit and gross margin increased primarily due to the impact of manufacturing cost reductions and an increase in the spread between raw material costs and selling prices. When compared to the second quarter of 2013, the decrease in gross profit was primarily due to an increase in overhead related to the planned annual maintenance partially offset by an increase in sales volume. The decrease in gross margin was primarily related to an increase in overhead related to the planned annual maintenance. The spread between selling prices and raw material costs remained relatively stable in the first nine months of 2013.
Selling, general and administrative expenses ("SG&A") totalled $20.5 million for the third quarter of 2013 compared to $19.3 million in the third quarter of 2012 and $20.2 million in second quarter of 2013. As a percentage of revenue, SG&A was 10.3%, 9.7% and 10.4% for the third quarter of 2013, the third quarter of 2012 and the second quarter of 2013, respectively. SG&A increased when compared to both periods primarily due to an increase in stock-based compensation expense.
Adjusted EBITDA was $26.8 million for the third quarter of 2013, $22.3 million for the third quarter of 2012 and $28.3 million for the second quarter of 2013. The increase in adjusted EBITDA in the third quarter of 2013 compared to the third quarter of 2012 was primarily due to higher gross margin. The decrease in adjusted EBITDA in the third quarter of 2013 compared to the second quarter of 2013 was primarily due to an increase in overhead related to the planned annual maintenance.
Net earnings for the third quarter of 2013 totalled $14.4 million compared to net earnings of $10.9 million for the third quarter of 2012 and net earnings of $15.1 million for the second quarter of 2013. The increase in net earnings for the third quarter of 2013 compared to the third quarter of 2012 was primarily due to an increase in gross profit and a decrease in interest expense partially offset by an increase in stock-based compensation expense. The decrease in net earnings for the third quarter of 2013 compared to the second quarter of 2013 was primarily due to a decrease in gross profit.
Adjusted net earnings amounted to $17.5 million for the third quarter of 2013 compared to $11.8 million for the third quarter of 2012. Adjusted net earnings were $5.7 million higher for the third quarter of 2013 compared to the third quarter of 2012 primarily due to higher gross profit and lower interest expense. Adjusted net earnings were $0.8 million lower for the third quarter of 2013 compared to $18.3 million for the second quarter of 2013 primarily due to a decrease in gross profit.
Adjusted fully diluted earnings per share for the third quarter of 2013 was $0.28 per share, a $0.09 per share increase compared to the third quarter of 2012 and a $0.02 per share decrease compared to the second quarter of 2013.
For a reconciliation of non-generally accepted accounting principles ("GAAP") financial measures to their most directly comparable GAAP financial measures, see the Non-GAAP Financial Measures section below.
Cash flows from operations before changes in working capital items increased in the third quarter of 2013 by $3.8 million to $25.0 million from $21.2 million in the third quarter of 2012 and decreased $0.8 million compared to the second quarter of 2013. The increase for the third quarter of 2013 compared to the third quarter of 2012 was primarily due to higher gross profit. The decrease over the second quarter of 2013 was primarily due to lower gross profit.
The Company had total cash and loan availability of $44.5 million as of September 30, 2013, $51.6 million as of June 30, 2013 and $87.6 million as of September 30, 2012. The decrease of $7.1 million in total cash and loan availability between June 30, 2013 and September 30, 2013 was due to the redemption of an aggregate principal amount of $18.7 million of Notes, a $5.2 million decrease in the borrowing base and the payment of a $4.9 million dividend, partially offset by free cash flows of $22.5 million for the quarter. The decrease of $43.1 million in total cash and loan availability between September 30, 2012 and September 30, 2013 was primarily due to the increase in total borrowings under the ABL facility, which was used to fund the redemption of an aggregate principal amount of $93.7 million of Notes that occurred during the twelve month period ended September 30, 2013. This increase was partially offset by cash flows from operations during the same period. The Company had cash and loan availability under its Asset-Based Loan facility exceeding $45 million as of November 12, 2013.
Total debt as of September 30, 2013 was $137.7 million, a decrease of $13.6 million from December 30, 2012. The debt to trailing twelve month adjusted EBITDA ratio was 1.4 as of September 30, 2013.
The Company will continue to focus on developing and selling higher margin products, reducing variable manufacturing costs and executing on the previously announced manufacturing rationalization projects.
Charges after 2013 related to equipment moves and workforce retention costs are estimated to be $5 to $7 million, primarily related to the South Carolina Project. Cash outflows expected after 2013 for equipment moves, workforce retention costs and environmental are estimated to be $8 to $11 million.
This press release contains certain non-GAAP financial measures as defined under applicable securities legislation, including EBITDA, adjusted EBITDA, adjusted net earnings (loss), adjusted earnings (loss) per share and free cash flows. As required by applicable securities legislation, the Company has provided reconciliations of those measures to the most directly comparable GAAP measures. Investors and other readers are encouraged to review the related GAAP financial measures and the reconciliation of non-GAAP measures to their most directly comparable GAAP measures and should consider non-GAAP measures only as a supplement to, not as a substitute for or as a superior measure to, measures of financial performance prepared in accordance with GAAP.
A reconciliation of the Company's EBITDA, a non-GAAP financial measure, to GAAP net earnings (loss), the most directly comparable GAAP measure, is set out in the EBITDA reconciliation table below. EBITDA should not be construed as earnings (loss) before income taxes, net earnings (loss) or cash flows from operating activities as determined by GAAP. The Company defines EBITDA as net earnings (loss) before (i) interest and other (income) expense; (ii) income tax expense (benefit); (iii) refinancing expense, net of amortization; (iv) amortization of debt issue costs; (v) amortization of intangible assets; and (vi) depreciation of property, plant and equipment. Adjusted EBITDA is defined as EBITDA before (i) manufacturing facility closures, restructuring and other related charges; (ii) stock-based compensation expense; (iii) impairment of goodwill; (iv) impairment of long-lived assets and other assets; (v) write-down on assets classified as held-for-sale; and (vi) other items as disclosed. The terms "EBITDA" and "adjusted EBITDA" do not have any standardized meanings prescribed by GAAP and are therefore unlikely to be comparable to similar measures presented by other issuers. EBITDA and adjusted EBITDA are not measurements of financial performance under GAAP and should not be considered as alternatives to cash flows from operating activities or as alternatives to net earnings (loss) as indicators of the Company's operating performance or any other measures of performance derived in accordance with GAAP. The Company has included these non-GAAP financial measures because it believes that it permits investors to make a more meaningful comparison of the Company's performance between periods presented. In addition, EBITDA and adjusted EBITDA are used by Management and the Company's lenders in evaluating the Company's performance.
A reconciliation of the Company's adjusted net earnings (loss), a non-GAAP financial measure, to GAAP net earnings (loss), the most directly comparable GAAP measure, is set out in the adjusted net earnings (loss) reconciliation table below. Adjusted net earnings (loss) should not be construed as net earnings (loss) as determined by GAAP. The Company defines adjusted net earnings (loss) as net earnings (loss) before (i) manufacturing facility closures, restructuring, and other related charges; (ii) stock-based compensation expense; (iii) impairment of goodwill; (iv) impairment of long-lived assets and other assets; (v) write-down on assets classified as held-for-sale; (vi) other items as disclosed; and (vii) income tax effect of these items. The term "adjusted net earnings (loss)" does not have any standardized meaning prescribed by GAAP and is therefore unlikely to be comparable to similar measures presented by other issuers. Adjusted net earnings (loss) is not a measurement of financial performance under GAAP and should not be considered as an alternative to net earnings (loss) as an indicator of the Company's operating performance or any other measures of performance derived in accordance with GAAP. The Company has included this non-GAAP financial measure because it believes that it permits investors to make a more meaningful comparison of the Company's performance between periods presented. In addition, adjusted net earnings (loss) is used by Management in evaluating the Company's performance because it believes it provides a more accurate indicator of the Company's performance.
Adjusted earnings (loss) per share is also presented in the following table and is a non-GAAP financial measure. Adjusted earnings (loss) per share should not be construed as earnings (loss) per share as determined by GAAP. The Company defines adjusted earnings (loss) per share as adjusted net earnings (loss) divided by the weighted average number of common shares outstanding, both basic and diluted. The term "adjusted earnings (loss) per share" does not have any standardized meaning prescribed by GAAP and is therefore unlikely to be comparable to similar measures presented by other issuers. Adjusted earnings (loss) per share is not a measurement of financial performance under GAAP and should not be considered as an alternative to earnings (loss) per share as an indicator of the Company's operating performance or any other measures of performance derived in accordance with GAAP. The Company has included this non-GAAP financial measure because it believes that it permits investors to make a more meaningful comparison of the Company's performance between periods presented. In addition, adjusted earnings (loss) per share is used by Management in evaluating the Company's performance because it believes it provides a more accurate indicator of the Company's performance.
Free cash flows, a non-GAAP measurement that is defined by the Company as cash flows from operating activities less purchases of property, plant and equipment and other assets. The Company is including this non-GAAP measure because it is used by Management and investors in evaluating the Company's performance and liquidity. Free cash flows does not have any standardized meaning prescribed by GAAP and is therefore unlikely to be comparable to similar measures presented by other issuers. Free cash flows should not be interpreted to represent residual cash flow available for discretionary purposes, as it excludes other mandatory expenditures such as debt service. A reconciliation of free cash flows to cash flows from operating activities, the most directly comparable GAAP measure, is set forth below.
As noted in the March 31, 2013 Interim Condensed Consolidated Financial Statements, the Company adopted Amended IAS 19 - Employee Benefits, on January 1, 2013 requiring retrospective application to operating results for fiscal years 2012 and 2011. As such, the unaudited interim condensed consolidated financial statements for the three and nine months ended September 30, 2013 reflect the Company's adoption of this guidance and include corresponding comparative information for 2012. See the Section entitled "Pension and Other Post-Retirement Benefit Plans" of the Management's Discussion and Analysis and Note 3 - Pension and Other Post-Retirement Benefit Plans of the unaudited interim condensed consolidated financial statements for the three and nine months ended September 30, 2013 for a summary of the impact of the adoption of this guidance on the Company's financial results.
A conference call to discuss Intertape's 2013 third quarter results will be held Wednesday, November 13, 2013, at 10 A.M. Eastern Time. Participants may dial 800-734-8507 (U.S. and Canada) and 1-212-231-2910 (International).
You may access a replay of the call by dialing 800-633-8284 (U.S. and Canada) or 1-402-977-9140 (International) and entering the Access Code 21683027. The recording will be available from November 13, 2013 at 12:00 P.M. until December 13, 2013 at 11:59 P.M. Eastern Time.
Intertape Polymer Group Inc. is a recognized leader in the development, manufacture and sale of a variety of paper and film-based pressure sensitive and water activated tapes, specialized polyolefin films, woven fabrics and complementary packaging systems for industrial and retail use. Headquartered in Montreal, Quebec and Sarasota, Florida, the Company employs approximately 1,800 employees with operations in 16 locations, including 10 manufacturing facilities in North America and one in Europe.
This press release contains "forward-looking information" within the meaning of applicable Canadian securities legislation and "forward-looking statements" within the meaning of United States federal securities legislation (collectively, "forward-looking statements"). All statements other than statements of historical facts included in this press release, including statements regarding the Company's industry and the Company's prospects, plans, financial position and business strategy may constitute forward-looking statements. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industries in which the Company operates as well as beliefs and assumptions made by the Company's management. Such statements include, in particular, statements about the Company's plans, prospects, financial position and business strategies. Words such as "may," "will," "expect," "continue," "intend," "estimate," "anticipate," "plan," "foresee," "believe" or "seek" or the negatives of these terms or variations of them or similar terminology are intended to identify such forward-looking statements. Although the Company believes that the expectations reflected in these forward-looking statements are reasonable, these statements, by their nature, involve risks and uncertainties and are not guarantees of future performance. Such statements are also subject to assumptions concerning, among other things: the Company's anticipated business strategies; anticipated savings from the Company's manufacturing plant rationalization initiatives; anticipated trends in the Company's business; anticipated cash flows from the Company's operations; availability of funds under the Company's Asset-Based Loan facility; and the Company's ability to continue to control costs. The Company can give no assurance that these estimates and expectations will prove to have been correct. Actual outcomes and results may, and often do, differ from what is expressed, implied or projected in such forward-looking statements, and such differences may be material. Readers are cautioned not to place undue reliance on any forward-looking statement. For additional information regarding some important factors that could cause actual results to differ materially from those expressed in these forward-looking statements and other risks and uncertainties, and the assumptions underlying the forward-looking statements, you are encouraged to read "Item 3. Key Information - Risk Factors" in the Company's annual report on Form 20-F for the year ended December 31, 2012 and the other factors contained in the Company's filings with the Canadian securities regulators and the US Securities and Exchange Commission. Each of these forward-looking statements speaks only as of the date of this press release. The Company will not update these statements unless applicable securities laws require it to do so.


text:
The binman shall inherit the earth... Residents will suffer as rubbish rules change again
What is it with local authorities, their acolytes, and dustbins? They are obsessed by the subject. Where some of us get off to sleep counting sheep, they stay awake counting dustbins.
It happens that I was born into a pre-dustbin generation. In those terrace-end days we had what were robustly known as middens.
A midden was a rough, open-fronted brick structure, usually adjoining a row of outdoor
lavatories, where we dumped our domestic rubbish. Every so often this heap of bluebottles and banana skins was shovelled into the corporation dustcart and the
sanitation department's work was done for another six months.
Consigned to history: The common black bin may become a thing of the past if communal bin trials are a success
Then we were moved into one of the new council estates, or 'social housing' as they're now known, where in each unkempt back garden was left a shiny new metal
dustbin, complete with sturdy lid. We insisted on calling them midden tins.
The bins were clatteringly emptied each Tuesday morning with the minimum of fuss. If you had an oversized item, such as an old mattress, the binmen would get rid of it for a small consideration. A couple of bob in their Christmas box — hence the institution
Boxing Day — guaranteed year-long impeccable service.
More from Keith Waterhouse for the Daily Mail...
Old beads are a girl's best friend 18/04/04
Voting with their bootees 14/04/04
When the Golden Mile gets even golder 11/04/04
A spell of buzz words at the Bee 07/04/04
Passing the buck along the line 04/04/04
How to win at a losing game... 31/03/04
Jobs for all in health 'n' safety 28/03/04
Back to the cloth cap with Clogworth 25/03/04
And so that was the year that was 22/03/04
So it went on for decade upon tranquil decade. Then suddenly, like an unexploded bomb, was heard, under the clanking of dustbin lids, the ticking of an insidious influence in the hitherto undisturbed world of refuse collection.
Recycling.
Do not run away with the idealistic idea that this had anything to do with saving Planet Earth for the polar bears. All that came later. The immediate impulse was
to save Planet Clogthorpe for rash investment in Iceland.
Under the slogan Where There's Muck There's Brass, local authorities set about separating the muck from the brass — or rather, setting their hapless subjects to
the task, on pain of huge penalties if they put their potato peelings in the wrong box on the right day or in the right box on the wrong day.
It was the time the binmen, no longer meek, inherited the earth. Like infants refusing to eat their spinach, they made any number of fussbudget demands upon the
taxpayers who had been their masters but were now their servants. Empty the bin? Sorry, squire, it's a quarter of an inch over the edge of the pavement. And it contains privet clippings which are outside our sphere.
No wonder the local authorities now don't allow them to solicit for Christmas boxes. They would get nothing but shirt buttons.
Then, abruptly, the wheels fell off the bandwagon. The wastepaper market was suddenly no longer worth what it was printed on. Junk was fetching less than
junk prices. The Steptoes had the administrators in. Councils which had backed recycling heavily, often in tandem with commercial firms, began to lose their monogrammed shirts.
Does this stop them dabbling in things they know little about? You must be joking. Still obsessed with dustbins, their newest, brightest idea is the communal bin, a kind of Turkish bath among bins, to be shared by 40 families. So the day of the communal
midden is back. It's already being tried out in Brighton.
The Big Bin, carrying 3,200 litres of rubbish, will leave 27,000 Brighton families without weekly collections. It cost £615,000 to install and is supposed to save £970,000 over seven years. That's without breakdowns. And you believe that?
A Big Bin for every 40 families will make our streets look like war bunkers. Can anyone explain — now that collecting cardboard has had its day — what was so wrong with dustbins?
Mumspeak
There seems to be a controversy of kinds, generated by a website called MumsRock, as to whether mothers like to be known as mums.
Speak as you find. Where I come from, mums were always called mams, or 'our mam' for short — 'R mam' as it would now be translated into text-speak.
There was a certain old world courtesy about this nomenclature. You could refer to your own mother as 'R mam' but anyone else's mam got her full title, as in 'Get on home, kid, your mother wants your boots for loaf tins' or 'Hey bighead, my mam wants to know if your mother will lend us your school cap to fetch a stone of flour.'
In my own family, there was no nonsense about mums or mams. Our mother brought us up to call her mother and nothing else. To our family, 'Dead, dead, and never called
me mother' was a speech embracing not tragedy but social superiority.


text:
A Cody Classic
The Ted Riback Residence in Rancho Mirage was one of William F. Cody's last residential commissions.
Lawrence Karol September 29, 2019 Current Digital, Home & Design, Real Estate
A round pool boasts a waterfall that splashes into it from the bottom of a shaded platform.
PHOTOGRAPHS COURTESY OF THE AGENCY
The term "hidden gem" gets thrown around quite a bit in real estate circles. Yet when it comes to describing this William F. Cody-designed home at the Tamarisk Country Club in Rancho Mirage, it would be an understatement. The Ted Riback Residence was designed by Cody in 1973 and completed in 1977, making it one of his last residential commissions. Riback, a Canadian entrepreneur, was head of the Tamarisk Country Club building committee and collaborated with Cody when the architect designed the community's clubhouse.
The home, which just came on the market for $1,895,000, features soaring ceilings and expansive views from nearly every room. It sits on an almost half-acre, south-facing lot where two holes and two tees of the club's golf course converge. "There's a line of clerestory windows in the living room that continue into the kitchen and all face north, like in the best art studios, filling the rooms with the most perfect light without the light ever being direct," says real estate agent Ruben Valerio of The Agency. There are also views of the San Jacinto Mountains to the west and the Santa Rosa Mountains to the south.
• READ NEXT: An exquisite William F. Cody design at Eldorado Country Club.
On the exterior, stucco walls and a bronze veneer stripe meld with flat terracotta roof tiles. Many original details have been retained throughout the home's interior, including the original kitchen and most of the bathrooms.
The home's historical pedigree is on full display beginning with the bronze veneer courtyard gates by Forms + Surfaces, a maker of architectural products that were – and still are – popular with high-end architects and designers. A Forms + Surfaces bronze veneer also adorns the perimeter of the house just below the roofline, as well as the columns on the back yard's covered patio, and the door to the pool bathroom.
The floor plan includes three bedrooms, three full bathrooms, and two half-baths in over 4,800 square feet. "One of the best original details is the brown Ultrasuede-clad den/office with the original brown Edward Fields inlaid carpet," says Valerio. "Even the vertical blinds are upholstered with brown Ultrasuede."
• READ NEXT: Desert Dreamers 7: The Architects.
"One of the best original details is the brown Ultrasuede-clad den/office with the original brown Edward Fields inlaid carpet," says Ruben Valerio of The Agency. "Even the vertical blinds are upholstered with brown Ultrasuede."
"The original bathrooms all make use of Corian, which was new at the time," he adds. "The shower walls are also slabs of Corian." Other original details include the beveled smoked glass mirror and orange grasscloth wallpaper in the front hall powder room; a Sub-Zero refrigerator/freezer that's been reconditioned, Thermador ovens and warming drawers and a Corningware/Amana secondary cooktop – all from 1977; and Formica kitchen cabinets that soar to 10 feet and retain their original bronze drawer pulls and bronze bullet hinges.
The living room features a combination of travertine tiles and original Edward Fields carpet that's been dyed to an updated color. Designer Steve Chase did a light makeover of the house in 1983 and added book-matched marble on the fireplace.
The living room features a combination of travertine tiles and original Edward Fields carpet that's been dyed to an updated color. Newer touches, that could easily be mistaken for vintage ones, include FliePaper wallpaper in the guest rooms, kitchen, and living room wet bar cove that were custom designed for the home. (FliePaper is a wallpaper line designed by the current owners and it's part of the permanent collection of the Cooper Hewitt Smithsonian Design Museum in New York City.)
Outdoors, a round pool boasts a waterfall that splashes into it from the bottom of a shaded platform.
"The current owners are in the process of applying for historical designation," notes Valerio. "Plans were found tucked away in the garage that confirm the house's pedigree. This was a truly significant discovery that adds to the rich history of Cody's mark on Tamarisk."
• READ NEXT: The Fertile Imagination of William F. Cody.
The Ted Riback Residence
70843 Tamarisk Lane, Rancho Mirage
For more information, contact Ruben Valerio, ruben.Valerio@TheAgencyRE.com, 818-903-9479; or Jeff Kohl, JKohl@TheAgencyRE.com, 424-230-3707.
The courtyard entrance is accentuated by bronze veneer gates from Forms + Surfaces, a maker of architectural products that were – and still are –popular with high-end architects and designers.
Newer touches, that could easily be mistaken for vintage ones, include FliePaper wallpaper in the guest rooms, kitchen, and living room wet bar cove that were custom designed for the home.
Cody Uncloaked
Arnold Palmer's Last Stand
Ready to Get Mod
Smart as a Whip
44 Things to Do in October
Desert Designs
Rancho Miragerancho mirage real estateTamarisk Country ClubWilliam F. Cody


text:
Q: Sending data via onclick I am trying to do a really simple forum with a simple reply system. Every response of a post has an icon where you can "quote", or reply rather, a different reply of the post. I have never encountered anything similar to this to I'm pretty lost.
I have tried sending hidden post data but the values accumulate and the last hidden input value is the one sent to the page that is going to catch it.
I am using CodeIgniter.
EDIT: I managed to do something via javascript, I am sending the data I want, but the taget page of the post doesn't show anything when I echo the data...
Javascript:
function citar(key)
{
    document.getElementsByName('esta-cita').value=key;
    document.getElementById('form-cita').submit();
}

Here is the code:
$contenido = '#'.$numRespuestas.'
'.$row['contenido'];
$this->table->add_row($contenido);

$pie = array(
    'data' => '

            ̶  de '.$row['autor'].
            ' el '.$row['dia'].
            ' a las '.$row['hora'].'

',
    'class' => 'pag-row'
);
$this->table->add_row($pie);

$tabla .= $this->table->generate();

$numRespuestas++;


text:
function [calibStruct, Calib] = AutoCalibrate(Calib,pointOrder,recalibrate,recalibrationPoints)

Calib.pointer = tryScreenOpen(Calib.window, Calib.bgcolor);

%%
rootpath = fileparts(mfilename('fullpath'));

% load audio
[wav, srate] = audioread(fullfile(rootpath, 'calib.wav'));

if size(wav, 2) == 1
    wav = horzcat(wav, wav);
end

audioPtr = PsychPortAudio('Open', [], 1, 1, srate, 2, [], [], [], 8);

% load image
[calibImg, ~, alpha] = imread(fullfile(rootpath, 'calib.png'));

if isempty(alpha)
    alpha = uint8(ones(size(calibImg, 1), size(calibImg, 2)) .* 255);
end

alphaScale = double(alpha) ./ 255;

% background color
for j = 1:3
    imlayer = double(calibImg(:,:,j));
    imlayer = imlayer .* alphaScale;
    bglayer = (1-alphaScale) .* Calib.bgcolor(j);
    calibImg(:,:,j) = uint8(floor(imlayer + bglayer));
end

%%

if (recalibrate==0)
    tetio_startCalib;
    calibrateThesePoints = true([1, length(pointOrder)]);
else
    calibrateThesePoints = false([1, length(pointOrder)]);
    for i = 1:length(recalibrationPoints)
        calibrateThesePoints(recalibrationPoints(i) == pointOrder) = true;
    end
end

WaitSecs(1);

clc
disp('Press space bar exactly when participant looks at dot');

pointCounter = 0;
HideCursor;
PsychPortAudio('FillBuffer', audioPtr, wav');
PsychPortAudio('Start', audioPtr, 0, 0, 1);
for i = 1:length(pointOrder);

    if calibrateThesePoints(i)

        pointCounter = pointCounter + 1;

        if recalibrate
            tetio_removeCalibPoint(Calib.points.x(pointOrder(i)), Calib.points.y(pointOrder(i)));
        end

        x = Calib.points.x(pointOrder(i));
        y = Calib.points.y(pointOrder(i));

        xPixels = floor(Calib.screen(3) .* x);
        yPixels = floor(Calib.screen(4) .* y);

        xNorm = xPixels / Calib.screen(3);
        yNorm = yPixels / Calib.screen(4);

        [pressedSpace, clickedScreen, x, y] = fixationImage(calibImg, Calib.pointer, false, Calib.stimsize, xPixels, yPixels);
        tetio_addCalibPoint(xNorm,yNorm);

        Calib.points.x(pointOrder(i)) = xNorm;
        Calib.points.y(pointOrder(i)) = yNorm;

        % draw line to next point
        if pointCounter ~= sum(calibrateThesePoints)
            nextLineIters = find(calibrateThesePoints);
            nextIter = nextLineIters(nextLineIters > i);
            xNext = Calib.points.x(pointOrder(nextIter(1)));
            yNext = Calib.points.y(pointOrder(nextIter(1)));

            xPixelsNext = floor(Calib.screen(3) .* xNext);
            yPixelsNext = floor(Calib.screen(4) .* yNext);

            drawLine([xPixels, yPixels],[xPixelsNext, yPixelsNext], ...
                Calib.pointer, Calib.linecolor, Calib.linesize);
        end

        WaitSecs(0.3);

    end
end
PsychPortAudio('Stop', audioPtr);
PsychPortAudio('Close', audioPtr);
ShowCursor;
tetio_computeCalib;
calibPlotData = tetio_getCalibPlotData;
calibStruct = CalibrationStruct(calibPlotData);
Screen('Close', Calib.pointer);

end

redpajama_set_name: RedPajamaGithub