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La ricerca find articoli where soggetti phrase all words 'FACTOR BETA-RECEPTOR' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 240 riferimenti
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Reddy, SAG
Signaling pathways in pancreatic cancer
CANCER JOURNAL
S.A.G. Reddy, "Signaling pathways in pancreatic cancer", CANCER J, 7(4), 2001, pp. 274-286
Alvi, AJ; Rader, JS; Broggini, M; Latif, F; Maher, ER
Microsatellite instability and mutational analysis of transforming growth factor beta receptor type II gene (TGFBR2) in sporadic ovarian cancer
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
A.J. Alvi et al., "Microsatellite instability and mutational analysis of transforming growth factor beta receptor type II gene (TGFBR2) in sporadic ovarian cancer", J CL PATH-M, 54(4), 2001, pp. 240-243
Vali, U; Kilk, A; Ustav, M
Bovine papillomavirus oncoprotein E5 affects the arachidonic acid metabolism in cells
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
U. Vali et al., "Bovine papillomavirus oncoprotein E5 affects the arachidonic acid metabolism in cells", INT J BIO C, 33(3), 2001, pp. 227-235
Rowland-Goldsmith, MA; Maruyama, H; Kusama, T; Ralli, S; Korc, M
Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation
M.A. Rowland-Goldsmith et al., "Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation", CLIN CANC R, 7(9), 2001, pp. 2931-2940
Hinz, B; Celetta, G; Tomasek, JJ; Gabbiani, G; Chaponnier, C
Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
MOLECULAR BIOLOGY OF THE CELL
B. Hinz et al., "Alpha-smooth muscle actin expression upregulates fibroblast contractile activity", MOL BIOL CE, 12(9), 2001, pp. 2730-2741
Kusano, M; Kakiuchi, H; Mihara, M; Itoh, F; Adachi, Y; Ohara, M; Hosokawa, M; Imai, K
Absence of microsatellite instability and germline mutations of E-cadherin, APC and p53 genes in Japanese familial gastric cancer
TUMOR BIOLOGY
M. Kusano et al., "Absence of microsatellite instability and germline mutations of E-cadherin, APC and p53 genes in Japanese familial gastric cancer", TUMOR BIOL, 22(4), 2001, pp. 262-268
DiMaio, D; Mattoon, D
Mechanisms of cell transformation by papillomavirus E5 proteins
D. DiMaio e D. Mattoon, "Mechanisms of cell transformation by papillomavirus E5 proteins", ONCOGENE, 20(54), 2001, pp. 7866-7873
Mattoon, D; Gupta, K; Doyon, J; Loll, PJ; DiMaio, D
Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein
D. Mattoon et al., "Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein", ONCOGENE, 20(29), 2001, pp. 3824-3834
Hammond, DE; Urbe, S; Woude, GFV; Clague, MJ
Down-regulation of MET, the receptor for hepatocyte growth factor
D.E. Hammond et al., "Down-regulation of MET, the receptor for hepatocyte growth factor", ONCOGENE, 20(22), 2001, pp. 2761-2770
Guda, K; Giardina, C; Nambiar, P; Cui, HY; Rosenberg, DW
Aberrant transforming growth factor-beta signaling in azoxymethane-inducedmouse colon tumors
K. Guda et al., "Aberrant transforming growth factor-beta signaling in azoxymethane-inducedmouse colon tumors", MOL CARCINO, 31(4), 2001, pp. 204-213
Herzog, CR; Crist, KA; Sabourin, CLK; Kelloff, GJ; Boone, CW; Stoner, GD; You, M
Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas
C.R. Herzog et al., "Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas", MOL CARCINO, 30(3), 2001, pp. 159-168
Chen, S; Hong, SW; Iglesias-de la Cruz, MC; Isono, M; Casaretto, A; Ziyadeh, FN
The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy
S. Chen et al., "The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy", RENAL FAIL, 23(3-4), 2001, pp. 471-481
Chin, BY; Mohsenin, A; Li, SX; Choi, AMK; Choi, ME
Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells:role of the p38 MAPK pathway
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
B.Y. Chin et al., "Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells:role of the p38 MAPK pathway", AM J P-REN, 280(3), 2001, pp. F495-F504
Levitzki, A
Protein tyrosine kinase inhibitors as therapeutic agents
BIOORGANIC CHEMISTRY OF BIOLOGICAL SIGNAL TRANSDUCTION
A. Levitzki, "Protein tyrosine kinase inhibitors as therapeutic agents", T CURR CHEM, 211, 2001, pp. 1-15
Saito, Y; Haendeler, J; Hojo, Y; Yamamoto, K; Berk, BC
Receptor heterodimerization: Essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation
Y. Saito et al., "Receptor heterodimerization: Essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation", MOL CELL B, 21(19), 2001, pp. 6387-6394
Ozawa, F; Friess, H; Tempia-Caliera, A; Kleeff, J; Buchler, MW
Growth factors and their receptors in pancreatic cancer
TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS
F. Ozawa et al., "Growth factors and their receptors in pancreatic cancer", TER CAR MUT, 21(1), 2001, pp. 27-44
Rotzer, D; Roth, M; Lutz, M; Lindemann, D; Sebald, W; Knaus, P
Type III TGF-beta receptor-independent signalling of TGF-beta 2 via T betaRII-beta, an alternatively spliced TGF-beta type II receptor
EMBO JOURNAL
D. Rotzer et al., "Type III TGF-beta receptor-independent signalling of TGF-beta 2 via T betaRII-beta, an alternatively spliced TGF-beta type II receptor", EMBO J, 20(3), 2001, pp. 480-490
McGonigle, S; Feeney, EL; Beall, MJ; Pearce, EJ
SIP, a novel SH3 domain-containing protein, interacts with Schistosoma mansoni receptor kinase 1
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
S. McGonigle et al., "SIP, a novel SH3 domain-containing protein, interacts with Schistosoma mansoni receptor kinase 1", MOL BIOCH P, 114(1), 2001, pp. 119-123
Ostman, A; Heldin, CH
Involvement of platelet-derived growth factor in disease: Development of specific antagonists
ADVANCES IN CANCER RESEARCH, VOL 80
A. Ostman e C.H. Heldin, "Involvement of platelet-derived growth factor in disease: Development of specific antagonists", ADV CANC R, 80, 2001, pp. 1-38
Enomoto, A; Esumi, M; Yamashita, K; Takagi, K; Takano, S; Iwai, S
Abnormal nucleotide repeat sequence in the TGF-beta RII gene in hepatocellular carcinoma and in uninvolved liver tissue
JOURNAL OF PATHOLOGY
A. Enomoto et al., "Abnormal nucleotide repeat sequence in the TGF-beta RII gene in hepatocellular carcinoma and in uninvolved liver tissue", J PATHOLOGY, 195(3), 2001, pp. 349-354
Franchi, A; Gallo, O; Sardi, I; Santucci, M
Downregulation of transforming growth factor beta type II receptor in laryngeal carcinogenesis
JOURNAL OF CLINICAL PATHOLOGY
A. Franchi et al., "Downregulation of transforming growth factor beta type II receptor in laryngeal carcinogenesis", J CLIN PATH, 54(3), 2001, pp. 201-204
Black, AR; Black, JD; Azizkhan-Clifford, J
Sp1 and kruppel-like factor family of transcription factors in cell growthregulation and cancer
A.R. Black et al., "Sp1 and kruppel-like factor family of transcription factors in cell growthregulation and cancer", J CELL PHYS, 188(2), 2001, pp. 143-160
De Crescenzo, G; Grothe, S; Zwaagstra, J; Tsang, M; O'Connor-McCourt, MD
Real-time monitoring of the interactions of transforming growth factor-beta (TGF-beta) isoforms with latency-associated protein and the ectodomains of the TGF-beta type II and III receptors reveals different kinetic models and stoichiometries of binding
G. De Crescenzo et al., "Real-time monitoring of the interactions of transforming growth factor-beta (TGF-beta) isoforms with latency-associated protein and the ectodomains of the TGF-beta type II and III receptors reveals different kinetic models and stoichiometries of binding", J BIOL CHEM, 276(32), 2001, pp. 29632-29643
Sato, A; Sasaoka, T; Yamazaki, K; Nakamura, N; Temaru, R; Ishiki, M; Takata, M; Kishida, M; Wada, T; Ishihara, H; Usui, I; Urakaze, M; Kobayashi, M
Glucosamine enhances platelet-derived growth factor-induced DNA synthesis via phosphatidylinositol 3-kinase pathway in rat aortic smooth muscle cells
A. Sato et al., "Glucosamine enhances platelet-derived growth factor-induced DNA synthesis via phosphatidylinositol 3-kinase pathway in rat aortic smooth muscle cells", ATHEROSCLER, 157(2), 2001, pp. 341-352
Chen, TP; Yan, W; Wells, RG; Rimm, DL; McNiff, J; Leffell, D; Reiss, M
Novel inactivating mutations of transforming growth factor-beta type I receptor gene in head-and-neck cancer metastases
T.P. Chen et al., "Novel inactivating mutations of transforming growth factor-beta type I receptor gene in head-and-neck cancer metastases", INT J CANC, 93(5), 2001, pp. 653-661
McGonigle, S; Beall, MJ; Feeney, EL; Pearce, EJ
Conserved role for 14-3-3 epsilon downstream of type I TGF beta receptors
S. McGonigle et al., "Conserved role for 14-3-3 epsilon downstream of type I TGF beta receptors", FEBS LETTER, 490(1-2), 2001, pp. 65-69
Yeager, ME; Halley, GR; Golpon, HA; Voelkel, NF; Tuder, RM
Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension
CIRCULATION RESEARCH
M.E. Yeager et al., "Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension", CIRCUL RES, 88(1), 2001, pp. E2-E11
Jones, SM; Kazlauskas, A
Growth factor-dependent signaling and cell cycle progression
CHEMICAL REVIEWS
S.M. Jones e A. Kazlauskas, "Growth factor-dependent signaling and cell cycle progression", CHEM REV, 101(8), 2001, pp. 2413-2423
Pietras, K; Ostman, A; Sjoquist, M; Buchdunger, E; Reed, RK; Heldin, CH; Rubin, K
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
K. Pietras et al., "Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors", CANCER RES, 61(7), 2001, pp. 2929-2934
Czuwara-Ladykowska, J; Gore, EA; Shegogue, DA; Smith, EA; Trojanowska, M
Differential regulation of transforming growth factor-beta receptors type I and II by platelet-derived growth factor in human dermal fibroblasts
J. Czuwara-Ladykowska et al., "Differential regulation of transforming growth factor-beta receptors type I and II by platelet-derived growth factor in human dermal fibroblasts", BR J DERM, 145(4), 2001, pp. 569-575
Sternberg, DW; Tomasson, MH; Carroll, M; Curley, DP; Barker, G; Caprio, M; Wilbanks, A; Kazlauskas, A; Gilliland, DG
The TEL/PDGF beta R fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways
D.W. Sternberg et al., "The TEL/PDGF beta R fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways", BLOOD, 98(12), 2001, pp. 3390-3397
Park, DS; Choi, YB; Han, MK; Kim, UH; Shin, JY; Yun, YD
Adaptor protein Lad relays PDGF signal to Grb2 in lung cells: A tissue-specific PDGF signal transduction
D.S. Park et al., "Adaptor protein Lad relays PDGF signal to Grb2 in lung cells: A tissue-specific PDGF signal transduction", BIOC BIOP R, 284(2), 2001, pp. 275-281
Yasuda, Y; Nakamura, J; Hamada, Y; Nakayama, M; Chaya, S; Naruse, K; Nakashima, E; Kato, K; Kamiya, H; Hotta, N
Role of PKC and TGF-beta receptor in glucose-induced proliferation of smooth muscle cells
Y. Yasuda et al., "Role of PKC and TGF-beta receptor in glucose-induced proliferation of smooth muscle cells", BIOC BIOP R, 281(1), 2001, pp. 71-77
Fahey, MS; Dawbarn, D; Allen, SJ; Paterson, IC; Prime, SS
Expression of recombinant extracellular domain of the type II transforminggrowth factor-ss receptor: Utilization in a modified enzyme-linked immunoabsorbent assay to screen TGF-ss agonists and antagonists
M.S. Fahey et al., "Expression of recombinant extracellular domain of the type II transforminggrowth factor-ss receptor: Utilization in a modified enzyme-linked immunoabsorbent assay to screen TGF-ss agonists and antagonists", ANALYT BIOC, 290(2), 2001, pp. 272-276
Hinz, B; Mastrangelo, D; Iselin, CE; Chaponnier, C; Gabbiani, G
Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation
AMERICAN JOURNAL OF PATHOLOGY
B. Hinz et al., "Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation", AM J PATH, 159(3), 2001, pp. 1009-1020
Takemoto, M; Yokote, K; Nishimura, M; Shigematsu, T; Hasegawa, T; Kon, S; Uede, T; Matsumoto, T; Saito, Y; Mori, S
Enhanced expression of osteopontin in human diabetic artery and analysis of its functional role in accelerated atherogenesis
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
M. Takemoto et al., "Enhanced expression of osteopontin in human diabetic artery and analysis of its functional role in accelerated atherogenesis", ART THROM V, 20(3), 2000, pp. 624-628
Petti, LM; Ray, FA
Transformation of mortal human fibroblasts and activation of a growth inhibitory pathway by the bovine papillomavirus E5 oncoprotein
CELL GROWTH & DIFFERENTIATION
L.M. Petti e F.A. Ray, "Transformation of mortal human fibroblasts and activation of a growth inhibitory pathway by the bovine papillomavirus E5 oncoprotein", CELL GROWTH, 11(7), 2000, pp. 395-408
Ohwada, M; Suzuki, M; Saga, Y; Suzuki, T; Ikeda, M; Yamada, M; Sato, I
Mutational analysis of transforming growth factor beta receptor type II and DNA mismatch repair genes in sporadic endometrial carcinomas with microsatellite instability
M. Ohwada et al., "Mutational analysis of transforming growth factor beta receptor type II and DNA mismatch repair genes in sporadic endometrial carcinomas with microsatellite instability", ONCOL REP, 7(4), 2000, pp. 789-792
Osawa, H; Shitara, Y; Shoji, H; Mogi, A; Kuwano, H; Hagiwara, K; Takenoshita, S
Mutation analysis of transforming growth factor beta type II receptor, Smad2, Smad3 and Smad4 in esophageal squamous cell carcinoma
INTERNATIONAL JOURNAL OF ONCOLOGY
H. Osawa et al., "Mutation analysis of transforming growth factor beta type II receptor, Smad2, Smad3 and Smad4 in esophageal squamous cell carcinoma", INT J ONCOL, 17(4), 2000, pp. 723-728
Park, BK; Jang, JS; Park, K
Deletion of one adenine base within the polyadenine tract of transforming growth factor-beta receptor type II in human MDA-MB-231 breast cancer cell line
B.K. Park et al., "Deletion of one adenine base within the polyadenine tract of transforming growth factor-beta receptor type II in human MDA-MB-231 breast cancer cell line", INT J ONCOL, 17(3), 2000, pp. 473-478
Kadono, T; Kikuchi, K; Nakagawa, H; Tamaki, K
Expressions of various growth factors and their receptors in tissues from neurofibroma
T. Kadono et al., "Expressions of various growth factors and their receptors in tissues from neurofibroma", DERMATOLOGY, 201(1), 2000, pp. 10-14
Connecting signaling and cell cycle progression in growth factor-stimulated cells
S.M. Jones e A. Kazlauskas, "Connecting signaling and cell cycle progression in growth factor-stimulated cells", ONCOGENE, 19(49), 2000, pp. 5558-5567
Periyasamy, S; Ammanamanchi, S; Tillekeratne, MPM; Brattain, M
Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency
S. Periyasamy et al., "Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency", ONCOGENE, 19(40), 2000, pp. 4660-4667
Go, C; He, W; Zhong, L; Li, P; Huang, J; Brinkley, BR; Wang, XJ
Aberrant cell cycle progression contributes to the early-stage acceleratedcarcinogenesis in transgenic epidermis expressing the dominant negative TGF beta RII
C. Go et al., "Aberrant cell cycle progression contributes to the early-stage acceleratedcarcinogenesis in transgenic epidermis expressing the dominant negative TGF beta RII", ONCOGENE, 19(32), 2000, pp. 3623-3631
Itoh, K; Udagawa, N; Matsuzaki, K; Takami, M; Amano, H; Shinki, T; Ueno, Y; Takahashi, N; Suda, T
Importance of membrane- or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors
JOURNAL OF BONE AND MINERAL RESEARCH
K. Itoh et al., "Importance of membrane- or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors", J BONE MIN, 15(9), 2000, pp. 1766-1775
Tateishi, M; Kusaba, I; Masuda, H; Tanaka, T; Matsumata, T; Sugimachi, K
The progression of invasiveness regarding the role of transforming growth factor beta receptor type II in gastric cancer
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY
M. Tateishi et al., "The progression of invasiveness regarding the role of transforming growth factor beta receptor type II in gastric cancer", EUR J SUR O, 26(4), 2000, pp. 377-380
Wu, HB; Kumar, A; Tsai, WC; Mascarenhas, D; Healey, J; Rechler, MM
Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3
JOURNAL OF CELLULAR BIOCHEMISTRY
H.B. Wu et al., "Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3", J CELL BIOC, 77(2), 2000, pp. 288-297
Rao, JN; Li, L; Bass, BL; Wang, JY
Expression of the TGF-beta receptor gene and sensitivity to growth inhibition following polyamine depletion
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
J.N. Rao et al., "Expression of the TGF-beta receptor gene and sensitivity to growth inhibition following polyamine depletion", AM J P-CELL, 279(4), 2000, pp. C1034-C1044
Walker, RA
Transforming growth factor beta and its receptors: their role in breast cancer
R.A. Walker, "Transforming growth factor beta and its receptors: their role in breast cancer", HISTOPATHOL, 36(2), 2000, pp. 178-180
Akiyama, Y; Nagasaki, H; Yagi, KO; Nomizu, T; Yuasa, Y
beta-Catenin and adenomatous polyposis coli (APC) mutations in adenomas from hereditary non-polyposis colorectal cancer patients
CANCER LETTERS
Y. Akiyama et al., "beta-Catenin and adenomatous polyposis coli (APC) mutations in adenomas from hereditary non-polyposis colorectal cancer patients", CANCER LETT, 157(2), 2000, pp. 185-191
Tanabe, Y; Saito, M; Ueno, A; Nakamura, M; Takeishi, K; Nakayama, K
Mechanical stretch augments PDGF receptor beta expression and protein tyrosine phosphorylation in pulmonary artery tissue and smooth muscle cells
Y. Tanabe et al., "Mechanical stretch augments PDGF receptor beta expression and protein tyrosine phosphorylation in pulmonary artery tissue and smooth muscle cells", MOL C BIOCH, 215(1-2), 2000, pp. 103-113
Shi, ZQ; Yu, DH; Park, M; Marshall, M; Feng, GS
Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity
Z.Q. Shi et al., "Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity", MOL CELL B, 20(5), 2000, pp. 1526-1536
Blake, RA; Broome, MA; Liu, XD; Wu, JM; Gishizky, M; Sun, L; Courtneidge, SA
SU6656, a selective Src family kinase inhibitor, used to probe growth factor signaling
R.A. Blake et al., "SU6656, a selective Src family kinase inhibitor, used to probe growth factor signaling", MOL CELL B, 20(23), 2000, pp. 9018-9027
Maudsley, S; Zamah, AM; Rahman, N; Blitzer, JT; Luttrell, LM; Lefkowitz, RJ; Hall, RA
Platelet-derived growth factor receptor association with Na+/H+ exchanger regulatory factor potentiates receptor activity
S. Maudsley et al., "Platelet-derived growth factor receptor association with Na+/H+ exchanger regulatory factor potentiates receptor activity", MOL CELL B, 20(22), 2000, pp. 8352-8363
Teller, S; Eluwa, S; Koller, M; Uecker, A; Beckers, T; Baasner, S; Bohmer, FD; Mahboobi, S
Pyrrolo[3,4-c]-beta-carboline-diones as a novel class of inhibitors of theplatelet-derived growth factor receptor kinase
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
S. Teller et al., "Pyrrolo[3,4-c]-beta-carboline-diones as a novel class of inhibitors of theplatelet-derived growth factor receptor kinase", EUR J MED C, 35(4), 2000, pp. 413-427
Xu, ZW; Friess, H; Buchler, MW
Molecular biology of pancreatic cancer
Z.W. Xu et al., "Molecular biology of pancreatic cancer", EXP ONCOL, 22(1-2), 2000, pp. 8-14
Cherrington, JM; Strawn, LM; Shawver, LK
New paradigms for the treatment of cancer: The role of anti-angiogenesis agents
J.M. Cherrington et al., "New paradigms for the treatment of cancer: The role of anti-angiogenesis agents", ADV CANC R, 79, 2000, pp. 1-38
Puri, CP; Katkam, RR; Sachdeva, G; Patil, V; Manjramkar, DD; Kholkute, SD
Endometrial contraception: modulation of molecular determinants of uterinereceptivity
C.P. Puri et al., "Endometrial contraception: modulation of molecular determinants of uterinereceptivity", STEROIDS, 65(10-11), 2000, pp. 783-794
Tomoda, H; Omura, S
Lactacystin, a proteasome inhibitor: Discovery and its application in cellbiology
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
H. Tomoda e S. Omura, "Lactacystin, a proteasome inhibitor: Discovery and its application in cellbiology", YAKUGAKU ZA, 120(10), 2000, pp. 935-949
Ulrich, CD
Growth factors, receptors, and molecular alterations in pancreatic cancer - Putting it all together
MEDICAL CLINICS OF NORTH AMERICA
C.D. Ulrich, "Growth factors, receptors, and molecular alterations in pancreatic cancer - Putting it all together", MED CLIN NA, 84(3), 2000, pp. 697
Kim, HS; Woo, DK; Bae, SI; Kim, YI; Kim, WH
Microsatellite instability in the adenoma-carcinoma sequence of the stomach
LABORATORY INVESTIGATION
H.S. Kim et al., "Microsatellite instability in the adenoma-carcinoma sequence of the stomach", LAB INV, 80(1), 2000, pp. 57-64
Araki, T; Yamada, M; Ohnishi, H; Sano, S; Uetsuki, T; Hatanaka, H
Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons
T. Araki et al., "Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons", J NEUROCHEM, 74(2), 2000, pp. 659-668
Rotin, D; Staub, O; Haguenauer-Tsapis, R
Ubiquitination and endocytosis of plasma membrane proteins: Role of Nedd4/Rsp5p family of ubiquitin-protein ligases
JOURNAL OF MEMBRANE BIOLOGY
D. Rotin et al., "Ubiquitination and endocytosis of plasma membrane proteins: Role of Nedd4/Rsp5p family of ubiquitin-protein ligases", J MEMBR BIO, 176(1), 2000, pp. 1-17
Kami, K; Morikawa, Y; Sekimoto, M; Senba, E
Gene expression of receptors for IL-6, LIF, and CNTF in regenerating skeletal muscles
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
K. Kami et al., "Gene expression of receptors for IL-6, LIF, and CNTF in regenerating skeletal muscles", J HIST CYTO, 48(9), 2000, pp. 1203-1213
Suprynowicz, FA; Sparkowski, J; Baege, A; Schlegel, R
E5 oncoprotein mutants activate phosphoinositide 3-kinase independently ofplatelet-derived growth factor receptor activation
F.A. Suprynowicz et al., "E5 oncoprotein mutants activate phosphoinositide 3-kinase independently ofplatelet-derived growth factor receptor activation", J BIOL CHEM, 275(7), 2000, pp. 5111-5119
van Kerkhof, P; Grovers, R; dos Santos, CMA; Strous, GJ
Endocytosis and degradation of the growth hormone receptor are proteasome-dependent
P. van Kerkhof et al., "Endocytosis and degradation of the growth hormone receptor are proteasome-dependent", J BIOL CHEM, 275(3), 2000, pp. 1575-1580
MacDonald, JIS; Gryz, EA; Kubu, CJ; Verdi, JM; Meakin, SO
Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA
J.I.S. MacDonald et al., "Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA", J BIOL CHEM, 275(24), 2000, pp. 18225-18233
Madge, LA; Pober, JS
A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NF kappa Bin human endothelial cells
L.A. Madge e J.S. Pober, "A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NF kappa Bin human endothelial cells", J BIOL CHEM, 275(20), 2000, pp. 15458-15465
Rosenkranz, S; Ikuno, Y; Leong, FL; Klinghoffer, RA; Miyake, S; Band, H; Kazlauskas, A
Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression
S. Rosenkranz et al., "Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression", J BIOL CHEM, 275(13), 2000, pp. 9620-9627
Sommerfeld, MT; Schweigreiter, R; Barde, YA; Hoppe, E
Down-regulation of the neurotrophin receptor TrkB following ligand binding- Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB
M.T. Sommerfeld et al., "Down-regulation of the neurotrophin receptor TrkB following ligand binding- Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB", J BIOL CHEM, 275(12), 2000, pp. 8982-8990
Tamura, K; Kanzaki, T; Tashiro, J; Yokote, K; Mori, S; Ueda, S; Saito, Y; Morisaki, N
Increased atherogenesis in Otsuka Long-Evans Tokushima fatty rats before the onset of diabetes mellitus: association with overexpression of PDGF beta-receptors in aortic smooth muscle cells
K. Tamura et al., "Increased atherogenesis in Otsuka Long-Evans Tokushima fatty rats before the onset of diabetes mellitus: association with overexpression of PDGF beta-receptors in aortic smooth muscle cells", ATHEROSCLER, 149(2), 2000, pp. 351-358
Schneider, BG; Bravo, JC; Roa, JC; Roa, I; Kim, MC; Lee, KM; Plaisance, KT; McBride, CM; Mera, R
Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population
B.G. Schneider et al., "Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population", INT J CANC, 89(5), 2000, pp. 444-452
Iino, H; Simms, L; Young, J; Arnold, J; Winship, IM; Webb, SI; Furlong, KL; Leggett, B; Jass, JR
DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer
H. Iino et al., "DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer", GUT, 47(1), 2000, pp. 37-42
Jass, JR; Iino, H; Ruszkiewicz, A; Painter, D; Solomon, MJ; Koorey, DJ; Cohn, D; Furlong, KL; Walsh, MD; Palazzo, J; Edmonston, TB; Fishel, R; Young, J; Leggett, BA
Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum
J.R. Jass et al., "Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum", GUT, 47(1), 2000, pp. 43-49
Agrotis, A; Condron, M; Bobik, A
Alternative splicing within the TGF-beta type I receptor gene (ALK-5) generates two major functional isoforms in vascular smooth muscle cells
A. Agrotis et al., "Alternative splicing within the TGF-beta type I receptor gene (ALK-5) generates two major functional isoforms in vascular smooth muscle cells", FEBS LETTER, 467(1), 2000, pp. 128-132
Jazayeri, A; McGee, J; Shimamura, T; Cross, SB; Bejcek, BE
SHP-2 can suppress transformation induced by platelet-derived growth factor
A. Jazayeri et al., "SHP-2 can suppress transformation induced by platelet-derived growth factor", EXP CELL RE, 254(2), 2000, pp. 197-203
Homma, S; Oppenheim, RW; Yaginuma, H; Kimura, S
Expression pattern of GDNF, c-ret, and GFR alpha s suggests novel roles for GDNF ligands during early organogenesis in the chick embryo
S. Homma et al., "Expression pattern of GDNF, c-ret, and GFR alpha s suggests novel roles for GDNF ligands during early organogenesis in the chick embryo", DEVELOP BIO, 217(1), 2000, pp. 121-137
Laird, AD; Vajkoczy, P; Shawver, LK; Thurnher, A; Liang, C; Mohammadi, M; Schlessinger, J; Ullrich, A; Hubbard, SR; Blake, RA; Fong, TAT; Strawn, LM; Sun, L; Tang, C; Hawtin, R; Tang, F; Shenoy, N; Hirth, KP; McMahon, G; Cherrington, JM
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
A.D. Laird et al., "SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors", CANCER RES, 60(15), 2000, pp. 4152-4160
Catasus, L; Matias-Guiu, X; Machin, P; Zannoni, GF; Scambia, G; Benedetti-Panici, P; Prat, J
Frameshift mutations at coding mononucleotide repeat microsatellites in endometrial carcinoma with microsatellite instability
L. Catasus et al., "Frameshift mutations at coding mononucleotide repeat microsatellites in endometrial carcinoma with microsatellite instability", CANCER, 88(10), 2000, pp. 2290-2297
Leppanen, O; Miyazawa, K; Backstrom, G; Pietras, K; Sjoblom, T; Heldin, CH; Ostman, A
Predimerization of recombinant platelet-derived growth factor receptor extracellular domains increases antagonistic potency
O. Leppanen et al., "Predimerization of recombinant platelet-derived growth factor receptor extracellular domains increases antagonistic potency", BIOCHEM, 39(9), 2000, pp. 2370-2375
Botchkareva, NV; Botchkarev, VA; Welker, P; Airaksinen, M; Roth, W; Suvanto, P; Muller-Rover, S; Hadshiew, IM; Peters, C; Paus, R
New roles for glial cell line-derived neurotrophic factor and neurturin - Involvement in hair cycle control
N.V. Botchkareva et al., "New roles for glial cell line-derived neurotrophic factor and neurturin - Involvement in hair cycle control", AM J PATH, 156(3), 2000, pp. 1041-1053
Sakuma, K; Watanabe, K; Sano, M; Kitajima, S; Sakamoto, K; Uramoto, I; Totsuka, T
The adaptive response of transforming growth factor-beta 2 and -beta RII in the overloaded, regenerating and denervated muscles of rats
ACTA NEUROPATHOLOGICA
K. Sakuma et al., "The adaptive response of transforming growth factor-beta 2 and -beta RII in the overloaded, regenerating and denervated muscles of rats", ACT NEUROP, 99(2), 2000, pp. 177-185
Price, WA
Peptide growth factors regulate insulin-like growth factor binding proteinproduction by fetal rat lung fibroblasts
W.A. Price, "Peptide growth factors regulate insulin-like growth factor binding proteinproduction by fetal rat lung fibroblasts", AM J RESP C, 20(2), 1999, pp. 332-341
Kawate, S; Takenoshita, S; Ohwada, S; Mogi, A; Fukusato, T; Makita, F; Kuwano, H; Morishita, Y
Mutation analysis of transforming growth factor beta type II receptor, Smad2, and Smad4 in hepatocellular carcinoma
S. Kawate et al., "Mutation analysis of transforming growth factor beta type II receptor, Smad2, and Smad4 in hepatocellular carcinoma", INT J ONCOL, 14(1), 1999, pp. 127-131
Hicke, L
Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels
TRENDS IN CELL BIOLOGY
L. Hicke, "Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels", TR CELL BIO, 9(3), 1999, pp. 107-112
Jones, SM; Klinghoffer, R; Prestwich, GD; Toker, A; Kazlauskas, A
PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1
S.M. Jones et al., "PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1", CURR BIOL, 9(10), 1999, pp. 512-521
Yokouchi, M; Wakioka, T; Sakamoto, H; Yasukawa, H; Ohtsuka, S; Sasaki, A; Ohtsubo, M; Valius, M; Inoue, A; Komiya, S; Yoshimura, A
APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-indnced mitogenesis
M. Yokouchi et al., "APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-indnced mitogenesis", ONCOGENE, 18(3), 1999, pp. 759-767
Walter, AO; Peng, ZY; Cartwright, CA
The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism
A.O. Walter et al., "The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism", ONCOGENE, 18(11), 1999, pp. 1911-1920
Shih, SC; Chien, CL; Tseng, KW; Lin, SC; Kao, CR
Immunohistochemical, studies of transforming growth factor-beta and its receptors in the gastric mucosa of patients with refractory gastric ulcer
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
S.C. Shih et al., "Immunohistochemical, studies of transforming growth factor-beta and its receptors in the gastric mucosa of patients with refractory gastric ulcer", J FORMOS ME, 98(9), 1999, pp. 613-620
Higashiyama, M; Ishikawa, S; Saito, T; Nakamura, T; Kusaka, I; Nagasaka, S; Honda, K; Saito, T
Inhibition by transforming growth factor-beta 1 of the cellular action of arginine vasopressin in cultured rat glomerular mesangial cells
Hypertension research
M. Higashiyama et al., "Inhibition by transforming growth factor-beta 1 of the cellular action of arginine vasopressin in cultured rat glomerular mesangial cells", HYPERTENS R, 22(3), 1999, pp. 173-180
Olivera, A; Edsall, L; Poulton, S; Kazlauskas, A; Spiegel, S
Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLC gamma
A. Olivera et al., "Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLC gamma", FASEB J, 13(12), 1999, pp. 1593-1600
Koponen, S; Keinanen, R; Roivainen, R; Hirvonen, T; Narhi, M; Chan, PH; Koistinaho, J
Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical, layers: Regulation by N-methyl-D-aspartate receptors and glucocorticoids
S. Koponen et al., "Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical, layers: Regulation by N-methyl-D-aspartate receptors and glucocorticoids", NEUROSCIENC, 93(3), 1999, pp. 985-993
Wang, XY; Gelfanov, V; Sun, HB; Tsai, SW; Yang, YC
Distinct actions of interleukin-9 and interleukin-4 on a hematopoietic stem cell line, EMLC1
EXPERIMENTAL HEMATOLOGY
X.Y. Wang et al., "Distinct actions of interleukin-9 and interleukin-4 on a hematopoietic stem cell line, EMLC1", EXP HEMATOL, 27(1), 1999, pp. 139-146
Zhao, RX; Zhao, ZJ
Tyrosine phosphatase SHP-2 dephosphorylates the platelet-derived growth factor receptor but enhances its downstream signalling
R.X. Zhao e Z.J. Zhao, "Tyrosine phosphatase SHP-2 dephosphorylates the platelet-derived growth factor receptor but enhances its downstream signalling", BIOCHEM J, 338, 1999, pp. 35-39
Govers, R; ten Broeke, T; van Kerkhof, P; Schwartz, AL; Strous, GJ
Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor
R. Govers et al., "Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor", EMBO J, 18(1), 1999, pp. 28-36
Friess, H; Kleeff, J; Korc, M; Buchler, MW
Molecular aspects of pancreatic cancer and future perspectives
H. Friess et al., "Molecular aspects of pancreatic cancer and future perspectives", DIGEST SURG, 16(4), 1999, pp. 281-290
Coleman, WB; Tsongalis, GJ
The role of genomic instability in human carcinogenesis
W.B. Coleman e G.J. Tsongalis, "The role of genomic instability in human carcinogenesis", ANTICANC R, 19(6A), 1999, pp. 4645-4664
Komura, K; Masuda, H; Esumi, M
Two types of sporadic multiple colorectal cancers with and without HNPCC-like genetic instability
HEPATO-GASTROENTEROLOGY
K. Komura et al., "Two types of sporadic multiple colorectal cancers with and without HNPCC-like genetic instability", HEP-GASTRO, 46(30), 1999, pp. 3115-3120
Menke, A; Geerling, I; Giehl, K; Vogelmann, R; Reinshagen, M; Adler, G
Transforming growth factor-beta-induced upregulation of transforming growth factor-beta receptor expression in pancreatic regeneration
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
A. Menke et al., "Transforming growth factor-beta-induced upregulation of transforming growth factor-beta receptor expression in pancreatic regeneration", BBA-MOL CEL, 1449(2), 1999, pp. 178-185
Togo, G; Okamoto, M; Shiratori, Y; Yamaji, H; Kato, J; Matsumura, M; Sano, T; Motojima, T; Omata, M
Does mutation of transforming growth factor-beta type II receptor gene play an important role in colorectal polyps?
G. Togo et al., "Does mutation of transforming growth factor-beta type II receptor gene play an important role in colorectal polyps?", DIG DIS SCI, 44(9), 1999, pp. 1803-1809


text:
Too Long, Didn't Watch? The Case for 8 Hour Films
in Features, Film, Uncategorized
In February, Filipino auteur Lav Diaz's latest film, A Lullaby to the Sorrowful Mystery, had its world premiere. While reviews have been mixed, the focus on this film has been less about its quality and more about its length. The historical drama, centred around the Philippine Revolution of 1896-98 and the disappearance of and search for Andrés Bonifacio, clocks in at a fairly staggering 8 hours and 5 minutes.
Such a runtime is not unique in Lav Diaz's filmography. Death in the Land of Encantos is an even more arduous 9 hours, while Norte, the End of History was a relatively brief 4 hours and 10 minutes. Other filmmakers like Bela Tarr, who's 7 hour drama Satatango premiered in Berlin in 1994, have also favoured a slower, more languid style of filmmaking. The question is, should filmmakers be making films of such epic scale, given how many of the cinema going audience will be put off by the 485 minute run time? If not, what is an appropriate length for a film?
Alfred Hitchcock once said that "the length of a film should be directly related to the endurance of the human bladder", and it has always been common practice for feature films to range between the 80 to 120 minute mark largely due to the theory that audiences' attention spans and physical comfort would be tested by anything of any significantly greater length. However, this seems to be a criticism reserved, unfairly, for cinema alone. It is not uncommon for stage plays to go on for 3 hours or more, which for some reason seems more acceptable.
It is true that the majority of plays have intervals, but then, so do some films. Certainly A Lullaby to the Sorrowful Mystery, the film which has kickstarted this discussion, was divided in two by a lunch break when it played in Berlin. Films like 2001: A Space Odyssey were created with a natural break in mind, a break still adhered to by cinemas when the film is periodically rereleased to the big screen. This then, is evidently not a watertight argument.
Furthermore, people also do not seem to have a problem with extraordinarily lengthy novels like War and Peace or the works of modern writers like Norman Mailer, despite the fact that these texts are substantially longer than the average length of popular books. Poetry is the same: Milton's Paradise Lost is to most poems what a one year long film would be to most films. Painters, sculptors and other design artists are even freer, there is no idea of how large or small, abstract or objective, easy or difficult to digest such works should be. It therefore seems that cinema is alone amongst all the art forms as bearing a public stigma regarding its boundaries.
The likely reason for this is that films have, since the inception of the U.S. studio system in the early 20th century, been regarded as entertainment for the masses, for everyone, rather than just for the intellectuals who visited art galleries and read epic literature. This idea can be seen in the way that cinema is approached in present day education. It seems to me that it is the least well represented of the arts, with literature, art and music all being covered by a young age. In comparison, the vast majority of students are not given the option to study film until they have reached university. The concept of 'screen time' and parents getting their children to read rather than watch anything on a screen ties into this philosophy that somehow film is less worthy a pastime than books. The result of this attitude is that films are now seen as having to be accessible to a wide audience, suiting the needs and requirements of the general public, who do not necessarily want to sit through a film that takes up a significant portion of their day.
My contention is that just as with literature, for example, there is cinema created for the mass market and which has a primary function of being disengaging and entertaining and making the filmmakers money, and then there is cinema made in order to explore deeper concepts and ideas. Just as you have Fifty Shades of Grey and Milan Kundera's The Unbearable Lightness of Being both existing within the realms of 'literature', so too do the likes of Iron Man and Carl Theodor Dreyer's Ordet inhabit the same medium. Clearly then, not all films should have to meet the lowest common demands of cinema going audiences. After all, if you don't want to see a film because you think it is too long then the solution is fairly simple: don't go and see it.
[Tim Abrams]
a lullaby to the sorrowful mysteryfilm featureglasgow universitylav diazlong filmtim abramsUniversity of Glasgow
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redpajama_set_name: RedPajamaCommonCrawl


text:
totalMem = 0
locations = 16
#IO

acc = 0 #Accumulator is in base 10 for simplicity, and so that signs works.
ProgCounter = 0

#Functions
def showRAMInt(mem_):
    intMem = list()
    for item in mem_:
        intMem.append(fullBinToInt(item))
    return(intMem)

def prepareRAM(locations):
    mem = list()
    for i in range(locations):
        mem.append("0000000000000000")
    totalMem = (locations/2)*8
    return(mem)

def fullIntToBin(integer):
    if integer < 32768:
        if integer >= 0:
            lead = "0"
            stem = format(integer, '015b')
        else:
            lead = "1"
            stem = format(integer*-1, '015b')
        return(lead+stem)
    else:
        raise(OverflowError)

def fullBinToInt(binary):
    if binary[0] == "1":
        #it's negative
        print(binary)
        binary = binary[1:16]
        print(binary)
        return((int(binary, 2)*-1))
    elif binary[0] == "0":
        #it's postive
        binary = binary[1:16]
        return(int(binary, 2))

#Initialise
memory = prepareRAM(locations)
totalMem = len(memory)*2
print(str(totalMem)+" bytes prepared ("+str(locations)+" locations)")
print(memory)

#Instructions
def addLoc(loc):
    loc = str(loc)
    #print(loc+" loc")
    global acc
    #print(lookUpLoc(loc)+"lookedup")
    data = lookUpLoc(loc)
    #print(data+"data")
    #print(fullBinToInt(data))
    #print(str(acc)+"AccumulatorAdd")
    #print("Attempted to add "+str(int(acc))+" (acc) and "+str(int(fullBinToInt(data)))+" which gives "+str(int(fullBinToInt(data))+int(acc)))
    acc = int(int(acc) + int(fullBinToInt(data)))
    #print("AccumPostAdd "+str(acc))

def subLoc(loc):
    loc = str(loc)
    global acc
    data = lookUpLoc(loc)
    #print(fullBinToInt(data))
    acc = acc - int(fullBinToInt(data))

def lookUpLoc(loc):
    global memory
    global acc
    loc = int(loc)
    #print("triedtolookup "+str(loc))
    return(memory[loc])

def storAcc(loc):
    global memory
    global acc
    #print(str(loc)+"location for store")
    #print(str("AccforStore"+str(acc)))
    loc = int(loc)
    memory[loc] = fullIntToBin(acc)

def jumpIfZero(loc):
    global acc
    loc = str(loc)
    if acc == 0:
        ProgCounter = int(loc)-1 #Must have a -1, as jump increments the counter as the counter increments after running...

def jumpIfPlus(loc):
    #print("JMPlus")
    global acc
    global ProgCounter
    loc = str(loc)
    if acc >= 0:
        ProgCounter = int(loc)-1 #And again here

def jump(loc):
    loc = str(loc)
    global ProgCounter
    ProgCounter = int(loc)-1 #Here also

def loadAcc(loc):
    global memory
    global acc
    acc = fullBinToInt(memory[int(loc)])

def output(form):
    global acc
    if form == 0:
        print(acc)
    if form == 1:
        print(chr(acc))
#Cycle
def fetch():
    #print("fetch")
    #print(lookUpLoc(ProgCounter)+" lookup")
    return(lookUpLoc(ProgCounter))

def decodeExec(data):
    global acc
    ##print("check")
    #print(data+"data")
    #print(fullBinToInt(data))
    dataInt = fullBinToInt(data)
    dataInt = str(dataInt)
    #print(dataInt+"dataInt")
    argument = dataInt[1:len(dataInt)]
    #print(argument)
    instruction = dataInt[0]
    #print(instruction)
    if instruction == "1":
        #print("ADD")
        #print(str(argument)+"argument")
        addLoc(argument)
    if instruction == "2":
        #print("SUB")
        #print(str(argument)+"argument")
        subLoc(argument)
    if instruction == "3":
        #print("STR")
        storAcc(argument)
    if instruction == "4":
        #print("JMZ")
        jumpIfZero(argument)
    if instruction == "5":
        #print("JPL")
        jumpIfPlus(argument)
    if instruction == "6":
        #print("JMP")
        jump(argument)
    if instruction == "7":
        #print("LDA")
        loadAcc(argument)
    if instruction == "8":
        #print("OUT")
        #print(acc)
        output(argument)
    elif instruction == "0":
        print("End of program")

memory[0] = '0000000001001101'
memory[1] = '0000000000010010'
memory[2] = '0000000000100101'
memory[3] = '0000000001010000'
memory[4] = '0000000000011100'
memory[5] = '0000000000100110'
memory[6] = '0000000000110010'
memory[7] = '0000000000000001'
memory[8] = '0000000000000001'
memory[9] = '1000000000000000'

while ProgCounter < locations:
    #print(memory[ProgCounter])
    #print(acc)
    if fetch() == '1000000000000000':
        print("End of program")
        break
    else:
        decodeExec(fetch())
        ProgCounter = int(ProgCounter) + 1

redpajama_set_name: RedPajamaGithub


text:
You searched for: Contributor Hennepin County Library Remove constraint Contributor: Hennepin County Library Subject Headings Public Libraries Remove constraint Subject Headings: Public Libraries Rights Status No Copyright - United States Remove constraint Rights Status: No Copyright - United States
1 - 100 of 204 results
Sort by Creator: A to Z
1. Business and Municipal Branch, Minneapolis Public Library, Minneapolis, Minnesota
Kairies, A. E.
Exterior of the Business and Municipal Branch of the Minneapolis Public Library in 1916, at 508 Second Avenue South, Minneapolis, Minnesota.
2. First Annual Report of the Minneapolis Public Library, for the year ending December 31, 1890
Minneapolis Public Library
Annual report featuring a statement by Board President T.B. Walker, and statistical and financial data reported by Librarian Herbert Putnam. Appendices include books by classification, circulation by month, circulation by classification, Northside branch circulation, Franklin branch circulation, summary of statistics, and a list of donors.
3. Augsburg Park Library, Hennepin County Library, Richfield, Minnesota
Exterior view of the Augsburg Park Library. The Augsburg Park Library has provided service in its current location since 1975. It is named after the park in which it is located. The library serves the Richfield community and residents of nearby Minneapolis. The library was renovated in 1988 and again in 2013.
Slides (photographs)
Circulation desk of the Augsburg Park Library. The Augsburg Park Library has provided service in its current location since 1975. It is named after the park in which it is located. The library serves the Richfield community and residents of nearby Minneapolis. The library was renovated in 1988 and again in 2013.
Reading chairs in the Augsburg Park Library. The Augsburg Park Library has provided service in its current location since 1975. It is named after the park in which it is located. The library serves the Richfield community and residents of nearby Minneapolis. The library was renovated in 1988 and again in 2013.
Information desk in the Augsburg Park Library. The Augsburg Park Library has provided service in its current location since 1975. It is named after the park in which it is located. The library serves the Richfield community and residents of nearby Minneapolis. The library was renovated in 1988 and again in 2013.
Exterior view of Augsburg Park Library which has provided service in its current location since 1975. It is named after the park in which it is located. The library serves the Richfield community and residents of nearby Minneapolis. The library was renovated in 1988 and again in 2013.
Augsburg Park Library has provided service in its current location since 1975. It is named after the park in which it is located. The library serves the Richfield community and residents of nearby Minneapolis. The library was renovated in 1988 and again in 2013.
10. Augsburg Park Library, Hennepin County Library, Richfield, Minnesota
A seating area in Augsburg Park Library which has provided service in its current location since 1975. It is named after the park in which it is located. The library serves the Richfield community and residents of nearby Minneapolis. The library was renovated in 1988 and again in 2013.
11. Bloomington Public Library, Hennepin County Library, Bloomington, Minnesota
Patrons browsing in the first Bloomington Public Library, located at 98th St. & Nicollet Avenue.
Patrons reading at a table first Bloomington Public Library, located at 98th St. & Nicollet Avenue.
Exterior view of the first Bloomington Public Library, located at 98th St. and Nicollet Avenue.
16. Bookmobile, Hennepin County Library, Minneapolis, Minnesota
View of the Hennepin County Library Bookmobile from the 1970s.
"This 1962 Hennepin County Library Bookmobile, one of two serving the 500 square mile area of rural and suburban Hennepin County, replaces a 1950 bookmobile. Carring 3000 volumes, it travels 1000 miles a month, serving over 6000 families, supplementing services of 23 county branch libraries."
A Hennepin County Library bookmobile.
Negatives (photographic)
Hennepin County Library's Mobile Library parked in a garage.
Children leave the Hennepin County bookmobile with armloads of books.
21. Bookmobile, Hennepin County Library, Minnesota
A woman in a fur coat peruses a book from the Hennepin County Library Bookmobile on a snowy day. Shown in the background is the Hennepin Hardware Company building.
22. Bookmobile, Minneapolis Public Library, Minneapolis, Minnesota
The Minneapolis Public Library Bookmobile is parked in downtown Minneapolis, Minnesota.
Color photographs
The Minneapolis Public Library Bookmobile.
The Minneapolis Public Library bookmobile parked in a lot at Fiftieth Street and Knox Avenue in April 1966. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
25. Book Service, Hennepin County Library, Minneapolis, Minnesota
View of an early Hennepin County Library bookmobile.
26. Brookdale Library, Hennepin County Library, Brooklyn Center, Minnesota
The children's area of the Brookdale Library which opened for service in 1981 at 6125 Shingle Creek Parkway, Brooklyn Center, Minnesota. A branch of the Hennepin County Library System, the library is housed in a larger complex that includes district courts and a Hennepin County service center.
Entrance to the Brookdale Library which opened for service in 1981 at 6125 Shingle Creek Parkway, Brooklyn Center, Minnesota. A branch of the Hennepin County Library System, the library is housed in a larger complex that includes district courts and a Hennepin County service center.
A hallway with art on display in the Brookdale Library which opened for service in 1981 at 6125 Shingle Creek Parkway, Brooklyn Center, Minnesota. A branch of the Hennepin County Library System, the library is housed in a larger complex that includes district courts and a Hennepin County service center.
A seating area near the stacks in the Brookdale Library which opened for service in 1981 at 6125 Shingle Creek Parkway, Brooklyn Center, Minnesota. A branch of the Hennepin County Library System, the library is housed in a larger complex that includes district courts and a Hennepin County service center.
The hallway leading to meeting rooms in the Brookdale Library which opened for service in 1981 at 6125 Shingle Creek Parkway, Brooklyn Center, Minnesota. A branch of the Hennepin County Library System, the library is housed in a larger complex that includes district courts and a Hennepin County service center.
Exterior of the Brookdale Library which opened for service in 1981 at 6125 Shingle Creek Parkway, Brooklyn Center, Minnesota. A branch of the Hennepin County Library System, the library is housed in a larger complex that includes district courts and a Hennepin County service center.
32. Brooklyn Center Library, Hennepin County Library, Brooklyn Center, Minnesota
Exterior view of the Brooklyn Center Library. The Brooklyn Center branch library opened in 1965.
Interior of the Brooklyn Center Library at 5601 Osseo Road (subsequently named Brooklyn Boulevard).
Patrons reading near the fireplace and periodicals section of the Brooklyn Center Library at 5601 Osseo Road (subsequently named Brooklyn Boulevard).
36. Brooklyn Park Library, Hennepin County Library, Brooklyn Park, Minnesota
Interior view of the Brooklyn Park Library. Brooklyn Park Library has provided service in its current location since 1976. Prior to 1976, the Hennepin County Library bookmobile served Brooklyn Park-area residents.
The Children's area of the Brooklyn Park Library. Brooklyn Park Library has provided service in its current location since 1976. Prior to 1976, the Hennepin County Library bookmobile served Brooklyn Park-area residents.
Exterior view of the Brooklyn Park Library. Brooklyn Park Library has provided service in its current location since 1976. Prior to 1976, the Hennepin County Library bookmobile served Brooklyn Park-area residents.
40. Central Library, Minneapolis Public Library, Minneapolis, Minnesota
A view of the back of the original Central Library building of Minneapolis Public Library, showing an intersection with streetcar tracks and various businesses. This building, at Tenth Street and Hennepin Avenue, opened in 1889 and was in service until 1959.
A sitting area in the Central Library of Minneapolis Public Library in Minneapolis, Minnesota. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002.
A banner celebrating the Minneapolis Public Library's 1985 centennial. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
This exterior view of the Central Library of Minneapolis Public Library highlights the library's sign. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
A view from above of the Central Library of Minneapolis Public Library. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
A view from above of one of the entrances to the Central Library of Minneapolis Public Library. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
A library staff member helping a patron in Minneapolis Public Library's Central Library. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
A woman looking at a book in the Literature and Language section of Minneapolis Public Library's Central Library. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
A view from above shows the roof and planetarium dome of the Central Library of Minneapolis Public Library. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
A view from above shows the loading dock of the Central Library of Minneapolis Public Library. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
A view from above of the Central Library of Minneapolis Public Library and parking lot. This facility, at 300 Nicollet Mall, was built in 1961 and housed the library until 2002. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
58. Champlin Branch, Hennepin County Library, Champlin, Minnesota
Exterior view of the Champlin Branch. Library service has been available to Champlin-area residents since the early 1900s. For most of the 20th century, library service was provided in a variety of small community locations.
Exterior view of the Champlin Public Library, a branch of the Hennepin County Library. The library moved into this building in 1973.
64. Champlin Public Library, Hennepin County Library, Champlin, Minnesota
65. Children looking at fish bowl at Minneapolis Public Library, Minneapolis, Minnesota
66. Crystal Library, Hennepin County Library, Crystal, Minnesota
Residents of Crystal, Minnesota were served by a branch of the Hennepin County Library that operated out of a variety of locations, until a number of nearby branches were consolidated into the Rockford Road Library, which opened in 1972.
67. Eden Prairie Community Library, Hennepin County Library, Eden Prairie, Minnesota
Exterior view of the Eden Prairie Community Library. Library service has been available to the Eden Prairie community since 1924, when the first library in Eden Prairie opened in the new Consolidated School. After it closed in 1950, the community was served by the Hennepin County Library bookmobile until 1973 and then a reading center until 1986, when a community library opened.�
68. Eden Prairie Public Library, Hennepin County Library, Eden Prairie, Minnesota
Interior view of the Eden Prairie Public Library. Library service has been available to the Eden Prairie community since 1924, when the first library in Eden Prairie opened in the new Consolidated School. After it closed in 1950, the community was served by the Hennepin County Library bookmobile until 1973 and then a reading center until 1986, when a community library opened.�
Library service has been available to the Eden Prairie community since 1924, when the first library in Eden Prairie opened in the new Consolidated School. After it closed in 1950, the community was served by the Hennepin County Library bookmobile until 1973 and then a reading center until 1986, when a community library opened.�
Exterior of the Eden Prairie Reading Center branch of the Hennepin County Library. This facility served the Eden Prairie community from 1973 to 1986.
A winter view of the Eden Prairie Reading Center branch of the Hennepin County Library. This facility served the Eden Prairie community from 1973 to 1986.
72. Edina Public Library, Hennepin County Library, Edina, Minnesota
Interior view of the Edina Public Library. Edina Library was first housed out of Linden Hills School beginning in 1921. In the following decades, the library operated out of various locations in the community. Its first permanent location opened in 1968 on West 50th Street.�
Exterior view of the Edina Public Library. Edina Library was first housed out of Linden Hills School beginning in 1921. In the following decades, the library operated out of various locations in the community. Its first permanent location opened in 1968 on West 50th Street.�
76. Excelsior Public Library, Hennepin County Library, Excelsior, Minnesota
Exterior view of the Excelsior Public Library. Library service to the South Lake communities of Deephaven, Excelsior, Greenwood, Shorewood and Tonka Bay was established beginning in 1922, when the library was housed out of the White House Hotel. For several decades, the library operated out of various locations in the community, with the first permanent library location opening on Third Street in 1965.�
The Excelsior Community Library shared a building with the city administrative offices for a time and served the communities of Deephaven, Excelsior, Greenwood, Shorewood and Tonka Bay
This building on Third Street was the first permanent location of the Excelsior Public Library, opened in 1965. Library service to the South Lake communities of Deephaven, Excelsior, Greenwood, Shorewood and Tonka Bay was established beginning in 1922, when the library was housed out of the White House Hotel. Until 1965, the library operated out of various locations in the community. In 2014, the library moved to a new building on Water Street in the heart of downtown Excelsior.
The Excelsior Community Library shared a building with the city administrative offices for a time and served the communities of Deephaven, Excelsior, Greenwood, Shorewood and Tonka Bay. The first permanent location was built on Third Street in 1965. In 2014 , the library moved to a new building at 337 Water Street in the heart of downtown Exclesior.
84. Fireplace - Rockford Road Library, Hennepin County Library, Crystal, Minnesota
Rockford Road Library opened in 1972 and was renovated in 2013. It serves the cities of Crystal, New Hope and Robbinsdale. For several decades prior to 1972, library service was provided to area residents out of various locations in the community. The library is named for one of the most historic roads in Hennepin County.
85. Franklin Branch, Minneapolis Public Library, Minneapolis, Minnesota
A drawing of the Franklin Branch of the Minneapolis Public Library. Opened in August 1914 at 1314 East Franklin Avenue, and designed by architect Edward L. Tilton, this was the first library building in Minneapolis to be built with funds from Andrew Carnegie. It was listed on the National Register of Historic Places in 2000.
Drawings (visual works)
Exterior view of the Franklin Branch of the Minneapolis Public Library. Opened in August 1914 at 1314 East Franklin Avenue, and designed by architect Edward L. Tilton, this was the first library building in Minneapolis to be built with funds from Andrew Carnegie. It was listed on the National Register of Historic Places in 2000.
87. Golden Valley Public Library, Hennepin County Library, Golden Valley, Minnesota
Exterior view of the Golden Valley Public Library. Located in Golden Valley Village Hall from 1958-1971, Golden Valley Library opened in its current location in 1971.�
Interior view of the Golden Valley Public Library. Located in Golden Valley Village Hall from 1958-1971, Golden Valley Library opened in its current location in 1971.�
92. Hamel Branch Library, Hennepin County Library, Medina, Minnesota
Exterior view of the tiny Hamel branch library, which operated from 1922-1968.
Exterior view of the Hamel branch library, which operated from 1922-1968.
94. Hopkins Branch Library, Hennepin County Library, Hopkins, Minnesota
Exterior view of the Hopkins Branch Library. Library service to the Hopkins community was established more than 100 years ago, when the library was housed in City Hall. The library moved to the historic Dow House in 1948 and then temporarily to a vacant restaurant in 1963. The library opened in its current location in 1968 and was renovated in 2002. The Hopkins Library merged with the Hennepin County Library system in 1973.
Exterior view of the Hopkins Branch Library. Library service to the Hopkins community was established more than 100 years ago, when the library was housed in City Hall. The library moved to the historic Dow House in 1948 and then temporarily to a vacant restaurant in 1963. The library opened in its current location in 1968 and was renovated in 2002. The Hopkins Library merged with the Hennepin County Library system in 1973
Exterior view of the Hopkins Public Library, a branch of the Hennepin County Library. Library service to the Hopkins, Minnesota community was established more than 100 years ago. The library was initially housed in City Hall, moved to the historic Dow House in 1948 and then temporarily to a vacant restaurant in 1963. The library opened in this building, at its current location at 22 Eleventh Avenue North, in 1968. The library joined Hennepin County Library in 1973 and its building was renovated in 2002.
98. Hosmer Branch, Minneapolis Public Library, Minnesota
Exterior view of the Hosmer branch of Minneapolis Public Library. Originally known as the Thirty-sixth Street Branch, this building was built in 1916 with funds from the Carnegie Corporation and was added to the National Register of Historic Places in 2000.
99. Jordan Branch, Minneapolis Public Library, Minneapolis, Minnesota
Housed in a school in the Jordan neighborhood of Minneapolis, the Jordan branch of Minneapolis Public Library was closed when the North Regional Library opened in 1971. Founded in 1885, the Minneapolis Public Library grew to include a Central Library and fourteen branches. In 2008 the library was merged into the Hennepin County Library system.
100. Linden Hills Branch, Minneapolis Public Library, Minneapolis, Minnesota
The Linden Hills branch of the Minneapolis Public Library moved into this building at 2900 West Forty-third Street in 1931, with a stock of 10,000 books. In 2000 the building was added to the National Register of Historic Places.
more Physical Format »
City of Bloomington
City of Edina
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Library Buildings
Bookmobiles
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more Subject Headings »
No Copyright - United States[remove]


text:
package comment

import (
	"fmt"
	"regexp"
	"strings"

	"github.com/google/go-github/github"
)

// Notification identifies comments with the following format:
// [NEEDS-REBASE] Optional arguments
type Notification string

// Match returns true if the comment is a notification
func (b Notification) Match(comment *github.IssueComment) bool {
	if comment.Body == nil {
		return false
	}
	match, _ := regexp.MatchString(
		fmt.Sprintf(`^\[%s\]`, strings.ToLower(string(b))),
		strings.ToLower(*comment.Body),
	)
	return match
}

// Command identifies messages sent to the bot, with the following format:
// /COMMAND Optional arguments
type Command string

// Match will return true if the comment is indeed a command
func (c Command) Match(comment *github.IssueComment) bool {
	if comment.Body == nil {
		return false
	}
	match, _ := regexp.MatchString(
		fmt.Sprintf("^/%s", strings.ToLower(string(c))),
		strings.ToLower(*comment.Body),
	)
	return match
}


text:
require './spec/spec_helper'

describe Spitball do
  before do
    use_success_bundler

    @gemfile = <<-end_gemfile
        source :rubygems
        gem "json_pure"
      end_gemfile

    @lockfile = <<-end_lockfile.strip.gsub(/\n[ ]{6}/m, "\n")
      GEM
        remote: https://rubygems.org/
        specs:
          json_pure (1.4.6)

      PLATFORMS
        ruby

      DEPENDENCIES
        json_pure
    end_lockfile

    @spitball = Spitball.new(@gemfile, @lockfile)
  end

  describe "cached?" do
    it "returns true if the tarball has already been cached" do
      expect(@spitball).not_to be_cached
      expect(@spitball).to receive(:get_specs).and_return([])
      @spitball.cache!
      expect(@spitball).to be_cached
    end
  end

  describe "cache!" do
    it "returns if the spitball is cached" do
      expect(@spitball).to receive(:cached?).and_return(true)
      expect(Spitball::FileLock).not_to receive(:acuire_lock)
      expect(Spitball::FileLock).not_to receive(:release_lock)
      expect(@spitball).not_to receive(:create_bundle)
      @spitball.cache!
    end

    it "creates the bundle if it acquires the lock" do
      file_lock = instance_double("Spitball::FileLock")

      expect(@spitball).to receive(:cached?).and_return(false).twice
      expect(@spitball).to receive(:get_file_lock).and_return(file_lock)
      expect(file_lock).to receive(:acquire_lock).and_return(true)
      expect(@spitball).to receive(:create_bundle)
      expect(file_lock).to receive(:release_lock)
      @spitball.cache!
    end

    it "does not create the bundle if it does not acquire the lock" do
      file_lock = instance_double("Spitball::FileLock")
      expect(@spitball).to receive(:get_file_lock).and_return(file_lock)
      expect(file_lock).to receive(:acquire_lock).and_return(false)
      expect(file_lock).not_to receive(:release_lock)
      expect(@spitball).not_to receive(:create_bundle)
      @spitball.cache!(false)
    end

    it "blocks if it does not acquire the lock and sync is true (default)" do
      cached = false
      done_caching = false

      file_lock = instance_double("Spitball::FileLock")
      expect(@spitball).to receive(:get_file_lock).and_return(file_lock).at_most(3).times
      expect(@spitball).to receive(:cached?).and_return(false).at_most(2).times
      expect(@spitball).to receive(:cached?).and_return(true)
      expect(file_lock).to receive(:acquire_lock).and_return(false).at_most(2).times

      t = Thread.new do
        @spitball.cache!
        done_caching = true
      end

      sleep 0.1
      expect(done_caching).to be false

      cached = true
      t.join
      expect(done_caching).to be true
    end
  end

  describe "generate_build_args" do
    it "returns an empty string for nil" do
      expect(@spitball.send(:generate_build_args, nil)).to eq('')
    end

    it "returns arguments prepended with double dashes for a string" do
      expect(@spitball.send(:generate_build_args, '--build-args=joesmith')).to eq('-- --build-args=joesmith')
    end
  end

  describe "create_bundle" do
    it "generates a bundle at the bundle_path" do
      expect(@spitball).to receive(:get_specs).and_return([])
      capture_stdout { @spitball.send :create_bundle }
      expect(File.exist?(@spitball.send(:tarball_path))).to be true
    end
  end

  describe "without_clause" do
    before do
      @gemfile = <<-end_gemfile
          source :rubygems
          group 'development' do
            gem "activerecord"
          end
        end_gemfile

      @lockfile = <<-end_lockfile.strip.gsub(/\n[ ]{8}/m, "\n")
        GEM
          remote: https://rubygems.org/
          specs:
            activemodel (3.0.1)
              activesupport (= 3.0.1)
              builder (~> 2.1.2)
              i18n (~> 0.4.1)
            activerecord (3.0.1)
              activemodel (= 3.0.1)
              activesupport (= 3.0.1)
              arel (~> 1.0.0)
              tzinfo (~> 0.3.23)
            activesupport (3.0.1)
            arel (1.0.1)
              activesupport (~> 3.0.0)
            builder (2.1.2)
            i18n (0.4.2)
            tzinfo (0.3.23)

        PLATFORMS
          ruby

        DEPENDENCIES
          activerecord
      end_lockfile
    end

    it "should use without" do
      @spitball = Spitball.new(@gemfile, @lockfile)

      expect(@spitball).to receive(:install_and_copy_spec).exactly(8).times

      @spitball.send :create_bundle
      @spitball = Spitball.new(@gemfile, @lockfile, :without => 'development')

      expect(@spitball).to receive(:install_and_copy_spec).exactly(1).times
      @spitball.send :create_bundle
    end
  end

  context "sources_opt" do
    it "does not add --clear sources for rubygems >= 1.4.0" do
      @spitball = Spitball.new(@gemfile, @lockfile)
      parsed_lockfile =  @spitball.instance_variable_get("@parsed_lockfile")
      stub_const("Gem::VERSION", "1.3.10")
      expect(@spitball.send(:sources_opt, parsed_lockfile.sources)).to eq("--source https://rubygems.org/")
    end

    it "adds --clear sources for rubygems >= 1.4.0" do
      @spitball = Spitball.new(@gemfile, @lockfile)
      parsed_lockfile =  @spitball.instance_variable_get("@parsed_lockfile")
      stub_const("Gem::VERSION", "1.4.0")
      expect(@spitball.send(:sources_opt, parsed_lockfile.sources)).to eq("--clear-sources --source https://rubygems.org/")
    end
  end
end

describe Spitball::FileLock do
  describe "acquire_lock" do
    before do
      Spitball::Repo.make_cache_dirs
      @lock_path = File.expand_path('test.lock', SPITBALL_CACHE)
      @lock = Spitball::FileLock.new(@lock_path)
    end

    it "returns true if the lock is acquired" do
      expect(@lock.acquire_lock).to be true
    end

    it "returns false if the lock is not acquired" do
      fork { @lock.acquire_lock; exit! }
      Process.wait

      expect(@lock.acquire_lock).to be false
    end
  end
end

describe Spitball::Repo do
  before do
    Spitball::Repo.make_cache_dirs
  end

  describe "make_cache_dirs" do
    it "creates the correct cache dir" do
      FileUtils.rm_rf(SPITBALL_CACHE)

      expect(File.exist?(SPITBALL_CACHE)).to be false
      Spitball::Repo.make_cache_dirs
      expect(File.exist?(SPITBALL_CACHE)).to be true
    end
  end

  describe "bundle_path" do
    it "generates paths with the correct cache" do
      expect(Spitball::Repo.bundle_path('digest')).to match /^#{SPITBALL_CACHE}/
    end

    it "generates paths with extensions" do
      expect(Spitball::Repo.bundle_path('digest', 'tgz')).to match /\.tgz$/
    end

    it "generates paths prefixed with bundle_" do
      expect(Spitball::Repo.bundle_path('digest', 'tgz')).to match /bundle_digest\.tgz$/
    end
  end

  describe "gemcache_path" do
    it "returns the correct path in the cache dir" do
      expect(Spitball::Repo.gemcache_path).to eq(File.join(SPITBALL_CACHE, "gemcache"))
    end
  end

  describe "exist?" do
    it "returns true if tarball for a digest exists" do
      expect(Spitball::Repo.exist?('digest')).to be false
      File.open(Spitball::Repo.bundle_path('digest', 'tgz'), 'w') {|f| f.write 'tarball!' }
      expect(Spitball::Repo.exist?('digest')).to be true
    end
  end

  describe "tarball" do
    it "returns the path of the cached tarball for a digest" do
      expect(Spitball::Repo.tarball('digest')).to eq(Spitball::Repo.bundle_path('digest', 'tgz'))
    end
  end

  describe "gemfile" do
    it "returns the path of the cached gemfile for a digest" do
      expect(Spitball::Repo.gemfile('digest')).to eq(
        Spitball::Repo.bundle_path('digest', 'gemfile'))
    end
  end

  describe "cached_digests" do
    it "returns a list of cached bundles" do
      File.open(Spitball::Repo.tarball('digest'), 'w') {|f| f.write 'tarball!' }
      File.open(Spitball::Repo.tarball('digest2'), 'w') {|f| f.write 'tarball2!' }

      expect(Spitball::Repo.cached_digests).to eq(['digest', 'digest2'])
    end
  end

  describe "clean_up_unused" do
    it "removes cached tarballs and gemfiles that haven't been accessed within a certain period" do
      File.open(Spitball::Repo.tarball('digest'), 'w') {|f| f.write 'tarball!' }
      File.open(Spitball::Repo.gemfile('digest'), 'w') {|f| f.write 'gemfile!' }

      sleep 3
      File.open(Spitball::Repo.tarball('digest2'), 'w') {|f| f.write 'tarball2!' }
      File.open(Spitball::Repo.gemfile('digest2'), 'w') {|f| f.write 'gemfile2!' }

      Spitball::Repo.clean_up_unused(1)

      expect(File.exist?(Spitball::Repo.tarball('digest'))).to be false
      expect(File.exist?(Spitball::Repo.gemfile('digest'))).to be false
      expect(File.exist?(Spitball::Repo.tarball('digest2'))).to be true
      expect(File.exist?(Spitball::Repo.gemfile('digest2'))).to be true
    end
  end
end

describe Spitball::Digest do
  it "generates a digest based on the spitball's options and gemfile" do
    expect([
      Spitball.new('gemfile contents', 'gemlock', :without => "system").digest,
      Spitball.new('gemfile contents 2', 'gemlock', :without => "system").digest,
      Spitball.new('gemfile', 'gemlock', :without => "other_group").digest,
      Spitball.new('gemfile', 'gemlock').digest,
      Spitball.new('gemfile', 'gemlock2').digest
    ].uniq.length).to eq(4)
  end

  it "provides a hash equal to the digest's hash"do
    spitball = Spitball.new('gemfile contents', 'gemlock contents')
    expect(spitball.hash).to eq(spitball.digest.hash)
  end
end

describe Spitball do
  context "mismatched" do
    before do
      use_success_bundler

      @gemfile = <<-end_gemfile
          source :rubygems
          gem "json_pure"
          gem "somethingelse"
        end_gemfile

      @lockfile = <<-end_lockfile.strip.gsub(/\n[ ]{6}/m, "\n")
        GEM
          remote: https://rubygems.org/
          specs:
            json_pure (1.4.6)

        PLATFORMS
          ruby

        DEPENDENCIES
          json_pure
      end_lockfile

    end

    describe "create_bundle failure" do
      it "should raise on create_bundle" do
        expect {
          Spitball.new(@gemfile, @lockfile)
        }.to raise_error(StandardError)
      end
    end
  end
end

describe Bundler::FakeDsl do
  it "should support a single group" do
    gemfile = <<-end_gemfile
        source :rubygems
        gem "json_pure"

        group :development do
          gem 'rails'
          gem 'json_pure'
        end
      end_gemfile

    dsl = Bundler::FakeDsl.new(gemfile)
    expect(dsl.__groups[:development]).to eq(["rails", "json_pure"])
  end

  it "should support multiple groups in one line" do
    gemfile = <<-end_gemfile
        source :rubygems
        gem "json_pure"

        group :development, :test do
          gem 'rails'
          gem 'json_pure'
        end
      end_gemfile

    dsl = Bundler::FakeDsl.new(gemfile)
    expect(dsl.__groups[:development]).to eq(["rails", "json_pure"])
    expect(dsl.__groups[:test]).to eq(["rails", "json_pure"])
  end

  it "should support multiple groups on several lines" do
    gemfile = <<-end_gemfile
        source :rubygems
        gem "json_pure"

        group :development do
          gem 'rails'
        end

        group :test do
          gem 'json_pure'
        end
      end_gemfile

    dsl = Bundler::FakeDsl.new(gemfile)
    expect(dsl.__groups[:development]).to eq(["rails"])
    expect(dsl.__groups[:test]).to eq(["json_pure"])
  end
end


text:
Western Michigan Odds | 2021 College Football Betting Lines
western michigan Schedule
western michigan Standings
western michigan Injuries
Western Kentucky vs Western Michigan 2019 First Responder Bowl Lines & Prediction
Western Michigan vs Michigan State 2019 College Football Week 2 Odds & Pick
Western Michigan vs BYU 2018 Famous Idaho Potato Bowl Odds & Pick
Western Michigan Broncos Odds
2021 Western Michigan Broncos Headlines, Best Lines
Salt Lake City, Western Michigan
Mid-American Conference
Waldo Stadium
Buster Bronco
Western Michigan vs. Central Michigan | 2020 NCAAF Expert Analysis
Posted: Tuesday, November 17, 2020 8:48, EST | 0 comments
Three games on the college football schedule Wednesday and as usual they are all from the Mid-American Conference. It's an important matchup from the West Division between the two leaders and a rivalry game when Western Michigan visits Central Michigan.
How to Bet Western Michigan at Central Michigan NCAA Football Odds & TV Info
When: Wednesday, 7 PM ET
Where: Kelly/Shorts Stadium
TV: ESPN2
Stream: ESPN app
Radio:com
Opening NCAAF Lines: CMU -1 (total 60.5)
Central Michigan lost 31-15 at Western Michigan last year. Jon Wassink threw for a touchdown and ran for another, LeVante Bellamy ran for 105 yards and a touchdown to lead the Broncos. Patrick Lupro stopped CMU's game-opening drive with an interception at midfield. Bellamy cashed in four plays later with an 11-yard run. By the time Wassink scored on a 1-yard plunge late in the third quarter, the Broncos led 24-0. WMU finished with 432 yards on offense.
This will be the 91st meeting between in-state rivals Western and Central Michigan. WMU leads 50-38-2 and has won the past two.
Why Bet on Western Michigan? | 2020 NCAAF Expert Analysis
The Broncos (2-0) won a crazy game last week against Toledo, 41-38. Trailing by 10 with 2:54 remaining the Broncos embarked on an 11-play, 70-yard drive that ended with Kaleb Eleby registering his second rushing touchdown of the night from one-yard away. After missing the extra point, the Broncos trailed 38-34 with 45 seconds remaining. WMU then got the onside kick and with 17 seconds remaining, Eleby faked a spike and found Jaylen Hall wide open in the end zone to complete the Broncos' comeback.
Toledo racked up 501 total yards of offense compared to WMU's 437. The Broncos posted 153 yards on the ground with Sean Tyler leading the way with 100 yards on 12 carries. He also had a career-high eight catches out of the backfield for 47 yards. Eleby completed 20 of his 29 pass attempts for 284 yards and a career-high three touchdowns. The redshirt sophomore also had a career-high two rushing touchdowns on five carries. Through the first two games Eleby has thrown for 546 yards and six touchdowns while completing 71 percent of his passes.
D'Wayne Eskridge has gone over 100 yards receiving in both games this season. He had seven receptions for 131 yards and a touchdown vs. CMU and 114 yards on three receptions in the season-opening win over Akron. It's the first time he has recorded back-to-back games with at least 100 yards receiving.
Five of Western Michigan's six scoring drives in the win over Toledo were under 3:00, including two of 30 seconds or less. The quick scoring resulted in a program low time of possession of 21:28 under head coach Tim Lester. Nine of WMU's 14 scoring drives this season have been under 3:00.
The Broncos have forced a turnover in each of the last five games dating back to last season. The last game WMU failed to force a turnover was on Nov. 5, 2019 against Ball State.
The last time WMU and CMU met in Mount Pleasant, the Broncos earned a 35-10 victory.
Why Bet on Central Michigan? | 2020 NCAAF Expert Analysis
CMU routed Northern Illinois 40-10 last week for the Chippewas' first 2-0 start in the league play since 2009. Lew Nichols rolled up 150 all-purpose yards and scored two touchdowns and the Central Michigan defense was dominant.
NIU had just two yards rushing in the second and third quarters combined and finished with 244 total yards. The Chippewas rolled up 433 yards in total offense, 299 of that total coming in the second half. Both NIU scores came in the fourth quarter, a field goal with 8:23 to play and a touchdown with 11 seconds left.
Chips QB Daniel Richardson, a redshirt freshman, completed 13 of his 19 pass attempts for 196 yards and two scores. He threw his first interception in his second career start. Freshman kicker Marshall Meeder booted a 40-yard field goal in the third quarter and was good on all seven of his PAT attempts.
Dallas Dixon has been a breakout player for the Chippewas this season after sitting out all last year due to transfer rules. Dixon leads CMU in receiving yards (113) and is tied for second in receptions (6). He opened the scoring against NIU with a 58-yard touchdown grab on CMU's second offensive play of the game.
Under Jim McElwain, the Chippewas are unbeaten (7-0) at home. CMU went 6-0 last year, the first time they have accomplished that feat since 1980. In those games, the Chippewas outscored their opponents, 294-133, at Kelly/Shorts Stadium.
CMU looks to go 3-0 to begin a season for the first time since 2016. The Chippewas began that year with wins over Presbyterian (49-3), at Oklahoma State (30-27) and against UNLV (44-21).
Game Trends
Broncos are 2-8 ATS in their last 10 games following a straight up win.
Broncos are 2-8-1 ATS in their last 11 games as an underdog.
Chippewas are 10-0-1 ATS in their last 11 Wednesday games.
Chippewas are 7-1 ATS in their last 8 home games.
Road team is 7-1 ATS in their last 8 meetings.
Western Michigan 34, Central Michigan 30
College Football Betting News
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Western Michigan Broncos Recent History, News & Betting Odds
We offer the latest Western Michigan Broncos Game Odds, Broncos Live Odds, This Weeks Western Michigan Broncos team totals, spreads and lines. The latest Western Michigan team stats, NCAA Football Futures & Specials, including Vegas Odds the Broncos Winning the College Football Playoff National Championship, Western Michigan NCAA Football News & other info on the Western Michigan Broncos. So what are you waiting for Signup and Bet on the Western Michigan Broncos Today!
Posted: Tuesday, November 17, 2020 8:48, EST
Three games on the college football schedule Wednesday and as usual they are all from the Mid-American Conference. It's an important matchup from the West Division between the two leaders and a rivalry game when Western Michigan visits Central Michigan. How to Bet Western Michigan at Central Michigan NCAA Football Odds & TV Info When: Wednesday, 7 PM ET Where: Read More
Toledo vs. Western Michigan | 2020 NCAAF Expert Analysis
Three games from the Mid-American Conference in college football on Wednesday night and the marquee matchup is a huge one from the West Division at Toledo visits Western Michigan. The Broncos are short home favorites on the NCAAF odds. How to Bet Toledo vs. Western Michigan NCAA Football Odds & TV Info When: Wednesday, 8 PM ET Where: Waldo Stadium Read More
Posted: Friday, December 27, 2019 3:00, EST
One of the problems with wagering on bowl games is figuring out how every team is going to approach their game. Some teams view these games as more of a vacation than a day at the office, while others come in ready to go after sitting on a tough loss for a few weeks. The best games that we see Read More
Posted: Monday, December 17, 2018 12:16, EST
The Brigham Young Cougars will look to close out their season in style when they take on the Western Michigan Broncos in the 2018 Famous Idaho Potato Bowl on Friday afternoon. With BYU a decisive double-digit favorite in this matchup, let's find out if the Cougars can get the win and ATS cover or whether the Broncos are the better Read More
Western Michigan vs Michigan NCAA Football Week 2 Lines
Posted: Thursday, September 6, 2018 4:58, EDT
Anyone who watches college football is well aware that the margin for error is very slim, at least for those teams who believe they have a shot at a conference title and a spot in the playoffs. If one of the top teams loses early in the season, they are essentially painted into a corner, as losing again usually means Read More
College Football Week 1: Western Michigan at USC Lines & Preview
Posted: Friday, September 1, 2017 8:45, EDT
2017 Heisman trophy favorite Sam Darnold and the fourth-ranked USC Trojans will look to make a statement when they host the 'new-look' Western Michigan Broncos in their College Football Week 1 regular season opener on Saturday night. The Trojans are expected to challenge for the national championship while Western Kentucky is heading in a new direction following their stupendous 2016 Read More
Western Michigan vs Wisconsin Cotton Bowl Pick & TV Info
If No. 1 Alabama was to be upset by No. 4 Washington in the College Football Playoff on Dec. 31, then No. 15 Western Michigan has a chance to complete the only unbeaten season in the nation on Jan. 2 when the Broncos, having the best season by far in school history, face No. 8 Wisconsin in the Cotton Bowl Read More
Western Michigan vs Wisconsin Cotton Bowl Early Pick
Posted: Monday, December 19, 2016 4:25, EST
The eighth-ranked Wisconsin Badgers will look to hand the unbeaten 15th-ranked Western Michigan Broncos their first loss of the season while finishing off their fine season with a victory when they take to the gridiron in the 2016 Goodyear Cotton Bowl. The Badgers are solid 7.5-point favorites to win beat the Broncos in college football lines. Western Michigan vs Wisconsin Read More
Week 14 College Football Betting: Western Michigan At Ohio
The 13th-ranked Western Michigan Broncos will look to remain unbeaten when they hit the road to take on the Ohio Bobcats in the MAC Championship on Friday. With this matchup offering what I believe is a ton of value for collegiate gridiron gaming enthusiasts, let's find out which team that value lies with. Analyzing The Week 14 College Football Betting Read More
Western Michigan at Ball State Betting Pick & Spread
Middle Tennessee vs. Western Michigan Free NCAA Football Pick
Sports in the State of Michigan
MLB | Detroit Tigers
NFL | Detroit Lions
NBA | Detroit Pistons
NHL | Detroit Red Wings
Basketball | Michigan State Spartans
Basketball | Michigan Wolverines
Football | Michigan Wolverines
Football | Michigan State Spartans
Football | Eastern Michigan Eagles
Football | Central Michigan Chippewas
Football | Western Michigan Broncos
Western Michigan Broncos Odds | 2021 NCAA Football
Western Michigan Broncos | College Football Playoff National Championship


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Will 2017 be the Year of Augmented Reality Technology?
Kees Friesland
In 2015 a lot of writers and tech commenters boldly stated that 2016 was the year of VR. For the most part, they were right, but VR's thunder was somewhat stolen through the noise made by augmented reality technology.
1 The VR Revolution
2 Every Day People
3 Augmented Reality Technology: What is it?
4 Best of Show
5 I Can See Clearly Now
The VR Revolution
In 2016 we saw the release of long-awaited virtual reality platforms such as the Vive and Oculus Rift. VR is finally here in a form that's good to use and ready for the mainstream. Of course, it's still pretty darn expensive and needs a powerful computer to work, but if you can get it chances are you'll love it.
The problem is that, cool as VR is, it's not super useful. For training simulations and video games, VR is an amazing technology. The problem is that it's a pretty expensive luxury. Conversely, video game consoles are cheap and double as media centers. Computers also do many things, ranging from entertainment to serious work.
That's VR's biggest problem at the moment: it only appeals to hardcore VR fans. Until its price comes down or more killer apps are released, it will remain a niche product.
Every Day People
Compare that to a technology such as smartphones. Today just about everyone has a smartphone. They've become a dominant form of technology that few people have trouble using and even fewer would fail to recognize.
VR is not like that at all. You have to isolate yourself from the outside world, which makes it a very personal experience. It happens in a room closed off from the world or, if you're brave, in public on a train or airplane.
Augmented reality technology is a related beast. It is still very different in practice. Between virtual reality and augmented reality technology it's the latter that's most likely to take the world by storm.
Augmented Reality Technology: What is it?
Before I get to all the interesting stuff that we can expect in 2017 and beyond, it's probably a good idea to explain things first.
Virtual reality is a term that just about everyone knows now, but augmented reality technology is probably not that well-known. At least not yet.
Basically, augmented reality technology takes the real world as it is and then adds a layer of digital information to it. Think of it as a sort of Robocop or Terminator vision.
For example, Microsoft's Hololens system can project virtual objects onto the walls and flat surfaces like tables. You can have a room full of bare walls and furniture, but through the Hololens it looks like there are paintings. TV screens, sculptures or whatever.
Apart from these sorts of physical object projections, it can be as simple as a heads-up display. A lot of things technically count as augmented reality.
The stuff to really get excited about, however, basically, amounts to a mix of virtual reality and augmented reality technology. Which is also referred to as mixed reality.
We fetl the presence of augmented reality technology strongly at the 2017 Consumer Electronics Expo. It seemed that every company had some sort of augmented reality technology product to show off alongside their VR offerings.
There's a definite drive to make slim and light augmented reality glasses that don't make you look like a dork.
One company doing really interesting work in this area is Lumus Vision. These guys are making transparent AR displays that can fit in spectacle frames, helmet visors or car windows.
Their SLEEK prototype is especially impressive with a VGA-resolution monocle and Android 4.1.2 support it almost seems like a finished product. As with augmented reality technology in things like the Hololens, the field of view is very narrow. Just 23 degrees diagonally, but it's an amazing start and shows that the tech is much further ahead than many people may think.
What About 2017?
There's a strong sentiment floating about that we'll see more and more companies offer some sort of augmented reality technology in 2017 or at least announce it.
These may turn out to be true or not, but they certainly point to an interesting AR year in 2017.
Augmented Apples
One rumor that's going around is augmented reality technology for the upcoming iPhone 8.
It's not just blind speculation either. Apple has bought up several augmented reality technology companies AND they've poached AR experts from companies they couldn't buy.
VR Companies are Buying In
Both HTC and Oculus are working on untethered mobile headsets that have external cameras and room-scale tracking. While these aren't mainly meant to be AR devices, there's no way AR won't play a role here.
Even Thinner
Lumus has competition in the form of Vuzix. Have a look at these thin Blade 3000 smart glasses that are set for release in 2017:
The specs on these are impressive, with a quad-core CPU and 32GB of RAM. It's what the first Google Glass was meant to be.
The asking price is likely going to be a steep $1000 at first. That will change and the price is expected to drop to half that by the end of 2018.
Premature efforts such as Google Glass were a big disappointment. New augmented reality technology looks much more useful. It's already priced better too.
While $1000 sounds like a lot of money, regular people are already happy to spend that much on an iPhone or other flagship mobile gadget. That means AR is about to directly compete with other mobile computing solutions for the first time.
Although the first customers are still mainly going to be enterprises, it's not longer a question of stumping up ten thousand dollars for a basic AR device.
Make no mistake, augmented reality technology is coming and there's a good chance that it will overtake VR as a dominant new medium. Especially since the requirements for VR can be so expensive. It's one of the main reasons why you may want to hold off spending your money on a VR headset. Waiting to see what happens in the AR space may be the more sensible thing to do. On the other hand if you cannot wait to get your hands on some of the best VR headsets make sure you make a deep research.
Related ItemsAndroidARiOSVR
Since getting his first 80286 DOS PC, Kees has been hooked on all kinds of tech. Until he finally manages to get that Iron Man suit, he'll scour the web looking for the next cool gadget or gizmo.
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