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About KMF
KMF2021
Concept Paper
Past KMF
4, 5 & 6 October 2021
THE INVENTION OF TOMORROW
Crafting Our New Collective Narrative
Since the inception of KMF, themes have been discussed ranging from a new context where uncertainty is normality to the need to generate growth with inclusion in an age of paradox; to whether or not good stewardship based on the political economy of location, environment, and demographics can overcome geography as destiny; to the juxtaposition between Artificial Intelligence and Human Intelligence; and most recently, to how we can 'Build our Collective Brain' to engender better outcomes for markets, firms, economies and, most importantly, societies.
The KMF2021 theme is: 'The Invention of Tomorrow: Crafting Our New Collective Narrative'. In upholding KMF traditions, panel discussions will continue to be organised along four core sessions: how various markets globally are affected; what the theme means to firms, and society at large; what are the imperatives of leadership and people.
Read the Concept Paper
Monday, 4 October 2021 (Malaysia Time)
9:00am - 9:05am WELCOME REMARKS AND INTRODUCTION TO KMF2021
Dato' Amirul Feisal Wan Zahir	Managing Director, Khazanah Nasional Berhad
9:10am - 9:30am OPENING ADDRESS
YAB Dato' Sri Ismail Sabri Yaakob	Prime Minister of Malaysia; and Chairman, Khazanah Nasional Berhad
9:35am - 10:20am SPECIAL ADDRESS: 'The Global Human Self'
Tamim Ansary	Author, teacher and lecturer
Introducer: Nicholas Khaw	Head, Research, Khazanah Nasional Berhad
10:25am - 11:15am CORE SESSION 1: MACRO AND MARKETS
Covid, Convergence, Correlations
Dr Andrew Ang	Head, Factor Investing Strategies, BlackRock
Joyce Chang	Chair of Global Research, J.P. Morgan
Nadia Jalil	Regional Head, Group Economics & Markets Analysis, CIMB Group
Chairperson: Mohamed Ridzuan Mohamed	Director, Research, Khazanah Nasional Berhad
11:20am - 12:05pm SPECIAL ADDRESS: 'The Great Reset: Shaping a Sustainable Energy Future'
Tengku Muhammad Taufik	President and Group CEO, PETRONAS
Introducer: Datuk Amran Hafiz Affifudin	Executive Director and Head, Energy & Infrastructure, Khazanah Nasional Berhad
12:05pm - 1:35pm Break
1:35pm - 2:20pm FIRESIDE CHAT with Manny Maceda
Manny Maceda	Worldwide Managing Partner, CEO and Chairman of the Board, Bain & Company
Moderator: Anand Panchalingam	Head, Digital & Technology, Managing Director's Office, Khazanah Nasional Berhad
2:25pm - 3:10pm FIRESIDE CHAT with Robert F. Smith
Robert F. Smith	Founder, Chairman and CEO, Vista Equity Partners
Moderator: Serena Tan	Executive Director, Head, Private Markets and Head, Financial Institutions Group (FIG), Khazanah Nasional Berhad
3:15pm - 4:00pm FIRESIDE CHAT with Dr Fred Hu
Dr Fred Hu	Founder, Chairman and CEO, Primavera Capital Group
Moderator: Dato' Amirul Feisal Wan Zahir	Managing Director, Khazanah Nasional Berhad
Programme is correct as of 1 October 2021
Tuesday, 5 October 2021 (Malaysia Time)
9:05am - 10:05am CORE SESSION 2: FIRMS AND TRANSFORMATION
Trials and Tribulations in Sustainability – How Do We Create Real Impact?
Luanne Sieh	Senior Managing Director, and Head, Group Sustainability, CIMB Group
Rohaya Yusof	Chief Investment Officer, Employees' Provident Fund (EPF)
Tanah Sullivan	Head of Sustainability, GoTo Group
Tariq Fancy	Former Chief Investment Officer for Sustainable Investing, BlackRock; and Founder, The Rumie Initiative
Chairperson: Nik Sharifidin Nik Mohamed Din	Head, Strategy, Khazanah Nasional Berhad
10:10am - 10:55am SPECIAL ADDRESS: 'Income inequality in the past three decades: Globally, in advanced economies, and in China'
Prof Branko Milanović	Centennial Professor, London School of Economics; and Senior Scholar, Stone Center on Socio-economic Inequality, City University of New York
Introducer: Tan Siaw Woan	Director, Research, Khazanah Nasional Berhad
11:00am - 12:00pm CORE SESSION 3: GROWTH AND DEVELOPMENT
Covid-19 and Broken Economic Systems: Towards Crafting a More Inclusive and Sustainable Growth Path
Allen Ng	Chief Economist, Securities Commission Malaysia
Tan Sri Dr Jemilah Mahmood	Professor and Executive Director, Sunway Centre for Planetary Health
Chairperson: Prof Jomo Kwame Sundaram	Research Advisor, Khazanah Research Institute
12:05pm - 12:50pm SPECIAL ADDRESS: '4 Billion Years of Innovation in the History of Life'
Prof Neil Shubin	Robert Bensley Distinguished Service Professor, and Associate Dean, Biological Sciences Division, University of Chicago
Introducer: Nik Marien Nik Ahmad Kamal	Senior Vice President, Investments, Khazanah Nasional Berhad
2:30pm - 3:15pm FIRESIDE CHAT with Nadiem Makarim
Nadiem Makarim	Minister of Education, Culture, Research and Technology, Republic of Indonesia; and Founder, Gojek
Moderator: Tengku Dato' Sri Azmil Zahruddin Raja Abdul Aziz	Chief Investment Officer, Khazanah Nasional Berhad
3:20pm - 4:05pm SPECIAL ADDRESS: 'The Changing Past & The Changing Future'
Prof Peter Frankopan	Professor of Global History, and Director, Oxford Centre for Byzantine Research, Oxford University
Introducer: Imran Ahmad	Director, Research, Khazanah Nasional Berhad
Wednesday, 6 October 2021 (Malaysia Time)
9:05am - 10:25am SPECIAL SESSION: INNOVATION WITHOUT BORDERS
Alison Sander	Director, Center for Sensing and Mining the Future, Boston Consulting Group (BCG)
Dr Amani Salim	Co-Founder and Chief Scientist and Technologist, nanoSkunkWorkX Sdn Bhd
Kamarul Azman Muhamed	Founder and CEO, Aerodyne Group
Shawn Henry	President of CrowdStrike Services, and Chief Security Officer, CrowdStrike
Introducer: Geoff Lee	Head, Telecommunications, Media & Technology, Khazanah Nasional Berhad
10:35am - 11:35am SPECIAL SESSION: PANDEMIC AND PUBLIC HEALTH
Dato' Prof Dr Adeeba Kamarulzaman	Professor of Medicine and Infectious Diseases, University of Malaya; and Adjunct Associate Professor, Yale University
Prof Jayati Ghosh	Professor of Economics, University of Massachusetts - Amherst
Chairperson: Nazihah Muhamad Noor	Research Associate, Khazanah Research Institute
11:40am - 12:45pm SPECIAL SESSION: CRAFTING OUR NATION'S NEW COLLECTIVE NARRATIVE
Dzuleira Abu Bakar	CEO, Technology Park Malaysia (TPM)
Kim Lim	Co-Founder, PichaEats
Loi Tuan Ee	CEO, Farm Fresh
Azmi Zainal	COO, Farm Fresh
Vinesh Sinha	Founder and CEO, FatHopes Energy
Introducer: Edmund Goh	Vice President, Knowledge Management, Research, Khazanah Nasional Berhad
2:30pm - 3:15pm SPECIAL ADDRESS: 'Mission Economy'
Prof Mariana Mazzucato	Professor in the Economics of Innovation and Public Value, and Founding Director, Institute for Innovation and Public Purpose, University College London
Introducer: Shahin Farouque Jammal Ahmad	Executive Director and Head, Special Situations, Khazanah Nasional Berhad
3:20pm - 4:20pm CORE SESSION 4: PEOPLE AND LEADERSHIP
We're All In It Together: Crafting Our New Collective Narrative
Melisa Melina Idris	Senior Editor, Astro AWANI
Chairperson: Selvendran Katheerayson	Head, Real Assets, Khazanah Nasional Berhad
4:25pm - 4:45pm CLOSING ADDRESS
YB Senator Tengku Datuk Seri Utama Zafrul Tengku Abdul Aziz	Minister of Finance Malaysia; and Board Member, Khazanah Nasional Berhad
Dato' Prof Dr Adeeba Kamarulzaman
Professor of Medicine and Infectious Diseases, University of Malaya; and Adjunct Associate Professor, Yale University
Professor Adeeba Kamarulzaman is a Professor of Medicine and Infectious Diseases at Universiti Malaya (UM) and an Adjunct Associate Professor at Yale University. She was Dean of the Faculty of Medicine, UM from 2011 to 2019. She is presently Chair of the UM Medical Centre COVID-19 Task Force and a member of the Selangor COVID-19 Task Force.
Professor Adeeba has played a leading role in the response to the HIV epidemic in Malaysia and globally and is currently the Chairman of the Malaysian AIDS Foundation and President of the International AIDS Society. She is a member of the WHO Science Council, UNAIDS Advisory Group and Co-Chairs the Lancet Commission on Health & Human Rights. Her achievements have been recognised through several national and international awards including an Honorary Doctor of Laws from her alma mater, Monash University, for her contributions to medicine and as a health advocate
Alison Sander
Director, Center for Sensing and Mining the Future, Boston Consulting Group (BCG)
Alison serves as the Director of BCG's Center for Sensing and Mining the Future (CSMF) and brings more than 25 years' experience working with senior management teams on complex challenges. The Center develops BCG's global Megatrend databases and provides guidance to organisations seeking to better understand trends that will shape their future.
Alison has designed significant growth strategies for clients across many sectors and has used Megatrends to help clients to find the next areas of growth. The Center tracks more than 100 trends that cut across the latest technological developments, demographic shifts, economic requirements, and consumer shifts, among others.
Alison has an MBA from Harvard Business School, a JD from Harvard Law School, and a BA in political science from the University of Chicago. Prior to BCG, she gained experience at Cambridge Transnational Associates (Founder & CEO), and Goldman Sachs. She served for 11 years on the Board of the World Resources Institute.
Allen Ng
Chief Economist, Securities Commission Malaysia
Allen was formerly the Director of Research at Khazanah Research Institute, overseeing the institute's research work on technology, employment and the state of Malaysia's economic development. Prior to that, he spent more than a decade at Bank Negara Malaysia. His last role at the central bank was Deputy Director of the Monetary Policy Department, where he was responsible for leading macroeconomic surveillance and research on matters relating to monetary policy. Before that, he was in the Economics Department, overseeing longer-term structural policy research to support the bank's economic advisory role to the Malaysian Government.
Allen has a BA and MPhil in Economics from the University of Cambridge. He is also a Chevening alumnus.
Dr Amani Salim
Co-Founder and Chief Scientist and Technologist, nanoSkunkWorkX Sdn Bhd
Dr. Amani Salim is the Chief Scientist and Technologist and Co Founder of nanoSkunkWorkX Sdn Bhd – a Malaysian startup focused on radical innovation in healthcare diagnostics, biosensors, energy storage, and advanced materials through high-scale, low-cost, and novel nanotechnology design process. A multidisciplinary engineer and researcher, project manager, and educator with a background in nanotechnology, biomedical, electrical, and materials engineering. Thrives under pressure with proven delivery and execution experience in time-sensitive, mission-critical projects, have worked with projects funded under domain-leading organisations such as NASA, EPA, and NIH. Passionate and engaging public speaker for youth and STEM engagement, addressing varied audiences such as students, corporate, and government bodies.
Dr Andrew Ang
Head, Factor Investing Strategies, BlackRock
Andrew Ang, PhD, is Head of BlackRock Systematic Wealth Solutions and Head of the Factor-Based Strategies Group. Dr. Ang is a well-known financial economist specialising in quantitative investing. Author of over 100 publications, Dr. Ang has published on equities, fixed income, optimal asset allocation, and alternative assets. He has written seminal papers in the area of factor investing, including research behind the minimum volatility factor. Dr. Ang has won many industry prizes and grants, including the Bernstein Fabozzi/Jacobs Levy award, and awards and grants from Q Group, INQUIRE, Netspar, and the National Science Foundation. Before joining BlackRock, Dr. Ang was the Ann F. Kaplan Professor of Business at Columbia Business School.
Azmi Zainal
COO, Farm Fresh
Azmi Zainal is the co-founder and COO of Farm Fresh, formerly known as The Holstein Milk Company, which produces the namesake dairy products sold across Malaysia and Singapore. He began his career with the Federal Land Development Authority (FELDA) in 1989 and Gemilang Packaging Sdn Bhd in 1997. Azmi has been instrumental in the growth of the company's operations and development of Farm Fresh's unique Home Dealers Network. Today, there are over 800 Farm Fresh home dealers around Malaysia, which has helped the company to access different customer markets whilst also empowering micro-entrepreneurs such as stay-at-home mothers to earn a stable income.
Prof Branko Milanović
Centennial Professor, London School of Economics; and Senior Scholar, Stone Center on Socio-economic Inequality, City University of New York
Branko Milanovic is Centennial Professor at the London School of Economics, and a Senior Scholar at the Stone Center on Socio-economic Inequality at the City University of New York. Milanovic's main area of work is income inequality, in individual countries and globally, including in pre-industrial societies. He has published articles on these topics in The Economic Journal, Review of Economics and Statistics and Journal of Economic Literature among others. His book Global Inequality: A New Approach for the Age of Globalization (2016), addresses economic and political issues of globalisation. It was translated in sixteen languages and awarded the 2017 Bruno Kreisky Prize and 2018 Hans Matthöfer Prize. Branko was awarded (jointly with Mariana Mazzucato) the 2018 Leontief Prize for Advancing the Frontiers of Economic Knowledge. His most recent book is Capitalism, Alone.
Dzuleira Abu Bakar
CEO, Technology Park Malaysia (TPM)
A Malaysian-grown tech professional with 17 years of experience across various industries with positions both in the private sector and GLIC/GLCs, Dzuleira started her career in the early 2000s and now carries with her the vast expertise on private equity and venture capitalism to lead Technology Park Malaysia (TPM). In her years of venture capital career, she has evaluated countless deals and invested in many Malaysian and regional companies. Dzuleira weaves these pieces of knowledge and experience as an advocate for the startup community while leading Malaysian Global Innovation and Creativity Centre (MaGIC) and initiated programmes critical to technology development such as National Innovation and Technology Sandbox (NTIS) and the critically-acclaimed Global Accelerator Programme (GAP). As TPM's CEO, she currently carries the mandate to transform the company into a premier tech park to lead the commercialisation of homegrown technology.
Dr Fred Hu
Founder, Chairman and CEO, Primavera Capital Group
Dr. Fred Hu is the founder and chairman of Primavera Capital Group. Prior to this, he was Chairman of Greater China and Partner at Goldman Sachs.
Fred is a respected economist who served at the International Monetary Fund. He previously sat on the Hong Kong Government's Strategic Development Committee, the Advisory Committee for the HKSFC and INED of HKEX.
Fred is the non-executive chairman of Yum China and serves as an Independent non-executive director of ICBC, UBS AG and Ant Group.
Fred holds a Master in Engineering Science from Tsinghua University and a Master and Ph.D. in Economics from Harvard University.
Prof Jayati Ghosh
Professor of Economics, University of Massachusetts - Amherst
Jayati Ghosh taught economics at Jawaharlal Nehru University, New Delhi for nearly 35 years, and is currently Professor of Economics at the University of Massachusetts at Amherst, USA. She has authored and/or edited 20 books, most recently The making of a catastrophe: Covid-19 and the Indian economy, (Aleph Books forthcoming 2021), published 200 scholarly articles, and received several awards for her research. She has advised governments in India and other countries, including as Member of the National Knowledge Commission of India (2005-09). She is the Executive Secretary of International Development Economics Associates (www.networkideas.org), an international network of heterodox development economists. She has consulted with several international organisations and is member of various boards and commissions, including the UN High Level Advisory Board on Economic and Social Affairs, and the WHO Council on the Economics of Health for All. She writes regularly for popular media like newspapers, journals and blogs.
Tan Sri Dr Jemilah Mahmood
Professor and Executive Director, Sunway Centre for Planetary Health
Dr. Mahmood is Professor and Executive Director of Sunway Centre for Planetary Health in Malaysia. She was the Special Advisor to the Prime Minister of Malaysia on Public Health from April 2020 to August 2021. She is a member of the Government of Malaysia's Economic Action Council and Climate Action Council.
Her previous appointments include the Under Secretary General for Partnerships at the International Federation of Red Cross and Red Crescent Societies (IFRC), Chief of the World Humanitarian Summit secretariat at the United Nations, and Chief of the Humanitarian Response Branch at UNFPA. She is the founder of MERCY Malaysia, a southern based international humanitarian organisation.
Dr. Mahmood graduated as a Doctor of Medicine (MD), has a Masters in Obstetrics & Gynaecology and is a Fellow of the Royal College of Obstetricians and Gynaecologists United Kingdom. She also completed executive education at the International Management and Development Centre, IMD Lausanne.
Chair of Global Research, J.P. Morgan
Joyce Chang is Chair of Global Research for J.P. Morgan's Corporate and Investment Bank, a global leader in Banking, Markets and Investor Services. Joyce began her career as an Emerging Markets Strategist and held top rankings in Institutional Investor surveys for Emerging Markets research from 1997 through 2012, earning 25 #1 individual rankings. In 2014, she was inducted into the Fixed Income Analyst Society Hall of Fame. Joyce was a Managing Director at Merrill Lynch and Salomon Brothers before joining J.P. Morgan Chase in 1999. She is the Senior Sponsor for J.P. Morgan's Corporate and Investment Bank Women on the Move Network, the network for employees of Asian heritage (AsPIRE) and Nonprofit Board Service. She has been included in American Banker's Most Powerful Women in Finance list since 2012 and Barron's 100 Most Influential Women in US Finance since 2020.
Kamarul Azman Muhamed
Founder and CEO, Aerodyne Group
Kamarul is the Founder and CEO of Aerodyne Group, a Malaysian-based drone solutions provider that is ranked second in the world by Drone Industry Insights of Germany. He was recently named 'EY Entrepreneur of The Year 2020', 'EY Technology Entrepreneur of The Year 2020 Malaysia' as well as 'SEBA Entrepreneur of The Year 2020'. Kamarul led Aerodyne from a 3-person startup in 2014 to a global company with presence in 35 countries in just 6 years. He is a TEDx speaker and a drone industry thought leader, who has presented his ideas and innovation on AI, Drones and Industry 4.0 around the world. An auditor by training, Kamarul spent his formative years in the city of London before switching his career to the tech industry upon returning to Malaysia after a 10-year stint in the UK. Kamarul is an avid explorer and has travelled to more than 100 countries, both for business and pleasure.
Kim Lim
Co-Founder, PichaEats
Kim Lim is the co-founder of PichaEats, a food business rebuilding lives of refugees in Malaysia.
PichaEats was the winner of The Chivas Venture 2017/18 in Malaysia and thrived into the Top 5 at the international level, the winner of Allianz's "Empowering Future Generation" in Munich, Germany, Booking Booster's Top 10 sustainable venture with Booking.com and recently Top 10 Asia's Social Enterprise.
She was awarded THE EDGE Inspiring Young Leaders 2017 awards, listed Forbes 30 under 30 Asia 2018, and Asia Tatler's Generation T in 2019.
Loi Tuan Ee
CEO, Farm Fresh
Loi Tuan Ee is the MD & CEO of Farm Fresh, formerly known as The Holstein Milk Company, which produces the namesake dairy products sold across Malaysia and Singapore. After leaving Century Bond Berhad in 2005 as Deputy Managing Director, Loi sought to establish fair pricing in local raw milk production and increase availability of fresh milk to Malaysians via Farm Fresh. Under Loi's leadership, Farm Fresh has achieved many accolades including the "Best Dairy Farm" by Asia Livestock in 2014 and the ASEAN Inclusive Business Award in 2020. In 2021, Farm Fresh became the first in Asia to receive the Humane Farm Animal Care certification. Loi is an Endeavor Entrepreneur since 2016 and has been nominated as Ernst & Young's Malaysia Entrepreneur of the Year in 2016.
Luanne Sieh
Senior Managing Director, and Head, Group Sustainability, CIMB Group
Luanne is the head of Group Sustainability at CIMB, one of ASEAN's leading banking groups, where she is responsible for transforming CIMB into a shaper of sustainable finance and responsible banking practices in Asia.
Luanne has extensive experience in sustainability, strategy and transformation, as well as change management. She has been involved in a number of fields, including financial services and consulting. She was also a founding member of a startup company.
Luanne holds a Bachelor of Arts and a Master's Degree in Manufacturing Engineering, as well as a Master of Arts from the University of Cambridge, and she is currently pursuing a Master of Liberal Arts in Sustainability at the University of Harvard Extension School.
linkedin.com/in/luanne-sieh
Manny Maceda
Worldwide Managing Partner, CEO and Chairman of the Board, Bain & Company
Manny Maceda is the Worldwide Managing Partner, CEO and Chairman of the Board of Bain & Company.
He is responsible for all aspects of the firm's strategy and people across Bain's global network of over 61 offices in 38 countries. Manny leads the firm in its mission to help clients create high levels of value while overseeing a culture perennially named as one of the world's best places to work.
Throughout his 30-year Bain career, Manny has advised CEOs from around the globe while being recognized as one of the foremost experts on advising companies through large-scale transformations.
He holds an MS in Management from the MIT Sloan School of Management and a BS in Chemical Engineering (magna cum laude) from the Illinois Institute of Technology. Manny is a member of the Advisory Board of the MIT Sloan School of Management.
Prof Mariana Mazzucato
Professor in the Economics of Innovation and Public Value, and Founding Director, Institute for Innovation and Public Purpose, University College London
Mariana Mazzucato (PhD) is Professor in the Economics of Innovation and Public Value at University College London (UCL), where she is Founding Director of the UCL Institute for Innovation & Public Purpose (IIPP). Her previous posts include the RM Phillips Professorial Chair at the Science Policy Research Unit (SPRU) at Sussex University. She is a selected fellow of the UK's Academy of Social Sciences (FAcSS) and of the Italian National Science Academy (Lincei).
She is winner of international prizes including the 2020 John von Neumann Award, the 2019 All European Academies Madame de Staël Prize for Cultural Values, and the 2018 Leontief Prize for Advancing the Frontiers of Economic Thought.
She is the author of three highly-acclaimed books: The Entrepreneurial State: Debunking Public vs. Private Sector Myths (2013), The Value of Everything: Making and Taking in the Global Economy (2018) and the newly released, Mission Economy: A Moonshot Guide to Changing Capitalism (2021).
Melisa Melina Idris
Senior Editor, Astro AWANI
A journalist with 15 years' experience in news media—newswires, print, online, radio and television—Melisa is currently Senior Editor at Astro AWANI, and anchor of 'Consider This' & 'The Future Is Female'. She was previously the Executive Producer of The Morning Run for BFM89.9 Radio. Among those Melisa has interviewed include Nobel Prize-winning economist Joseph Stiglitz, theoretical physicist Michio Kaku, the first humanoid Artificial Intelligence SOPHIA the Robot, and former Prime Minister Tun Dr Mahathir Mohamed. Melisa holds a Master in Journalism from New South Wales University, Sydney, and is an Economics & Public Administration graduate from Universiti Malaya. In 2017, she was a Wolfson Press Fellow with Cambridge University, researching news media in a Post-Truth era and the spread of disinformation.
Nadia Jalil
Regional Head, Group Economics & Markets Analysis, CIMB Group
Intan Nadia Jalil is the Regional Head, Group Economic and Market Analysis for CIMB Bank Berhad. Her previous appointments include the CEO of the PNB Research Institute, Associate Director of Economics at the Malaysian Aviation Commission, and Deputy Director of Research at Khazanah Research Institute. Nadia has 17 years' experience in macroeconomics research, and in developing comprehensive economic development policies, strategies, and plans in Malaysia and Southeast Asia, including a term as Malaysian economist for the World Bank. Nadia holds an MSc in Regional and Urban Planning Studies from the London School of Economics and Political Science, and graduated from the University of Cambridge, United Kingdom with a BA in Economics.
Minister of Education, Culture, Research and Technology, Republic of Indonesia; and Founder, Gojek
Nadiem Makarim is currently the Minister of Education, Culture, Research, and Technology Republic of Indonesia. Prior to the current position, he was a management consultant at McKinsey & Company (2006–2009), Co-Founder and Managing Director of Zalora Indonesia (2011–2012), Chief Innovation Officer at Kartuku (2013–2014). In 2010, he co-founded Gojek and served as Chief Executive Officer until 2019. He was educated at Brown University (BA) and at Harvard Business School (MBA).
Prof Neil Shubin
Robert Bensley Distinguished Service Professor, and Associate Dean, Biological Sciences Division, University of Chicago
Neil Shubin is the Robert Bensley Distinguished Service Professor at the University of Chicago and Associate Dean for academic strategy of the university's Biological Sciences Division. Shubin's research focuses on the evolution of new organs and he leads a laboratory that combines expeditionary paleontology and molecular biology to understand major transformations in the history of life.
He is the author of Some Assembly Required (2020), The Universe Within: The Deep History of the Human Body (2013) and Your Inner Fish: A Journey into the 3.5-Billion-Year History of the Human Body (2008). Your Inner Fish was named best book of the year by the National Academy of Sciences and was developed as a miniseries for PBS which won an Emmy in 2016.
Shubin earned his Ph.D. in organismic and evolutionary biology at Harvard and was elected to the American Academy of Arts and Sciences in 2009, the National Academy of Sciences in 2011 and the American Philosophical Society in 2017.
Prof Peter Frankopan
Professor of Global History, and Director, Oxford Centre for Byzantine Research, Oxford University
Peter Frankopan, Professor of Global History at Oxford University, is Senior Research Fellow of Worcester College and Director of the Oxford Centre for Byzantine Research – specialising in the Eastern Mediterranean, Russia, the Middle East, Central Asia and China. His rewriting of the history of the Crusades is monumental.
His phenomenally successful book, The Silk Roads: A New History of the World, has received magnificent acclaim from the most prestigious sources.
More recently, The New Silk Roads: The Present and Future of the World is also receiving gushing acclaim.
He works with United Nations Industrial Development Organisation (UNIDO) on the future of sustainable cities and on the Belt and Road Initiative. In 2017, he was appointed Senior Advisor and Academic Expert to a major project for the World Bank and Department for International Development (DFID) on Transport Corridors in South Asia. Professor Frankopan advises governments, inter-government agencies, institutions and corporations about geopolitics. He writes regularly for the global press.
www.peterfrankopan.com
Robert F. Smith
Founder, Chairman and CEO, Vista Equity Partners
Entrepreneur and philanthropist Robert F. Smith is one of the most preeminent technology investors and has been recognised as a thought leader for both his financial acumen and philanthropic vision. Smith is the Founder, Chairman and CEO of Vista Equity Partners. Vista currently has more than $77 billion in AUM, with a portfolio of over 70 companies that employ more than 75,000 people globally.
In 2020, Smith was named as one of TIME's 100 Most Influential People in the World and has been recognised by Forbes as one of the 100 Greatest Living Business Minds. He is the Chair of the Robert F. Kennedy Human Rights organisation, Chairman of Carnegie Hall, on the board of overseers of Columbia Business School and on the Board of Directors of the Business Roundtable.
Rohaya Yusof
Chief Investment Officer, Employees' Provident Fund (EPF)
Rohaya Mohammad Yusof was appointed as the Chief Investment Officer of Malaysia's Employees Provident Fund (EPF), in January 2020. She joined the EPF Investment Division in 2008 and has worked in various senior positions in Investment. Prior to joining EPF she has over 18 years Investment banking experience. She is currently the Chairman of Institutional Investors Council Malaysia and Board of Trustees, Yayasan Khazanah. Rohaya is also a member of the Board of Directors of Malaysia Resources Corporation Berhad, Projek Lebuhraya Usahasama Berhad, United Plantations Berhad and Yinson Holdings Berhad.
Rohaya holds a degree in Bachelor of Commerce from Australia National University and is an associate member of CPA Australia.
Shawn Henry
President of CrowdStrike Services, and Chief Security Officer, CrowdStrike
Shawn Henry is President of the CrowdStrike Services Division, leading world-class teams of cybersecurity professionals engaged in response operations across every major commercial sector, protecting organisations' sensitive data and networks globally.
Shawn spent 24 years at the FBI, becoming Executive Assistant Director overseeing all cyber investigations worldwide. He led the establishment of the National Cyber Investigative Joint Task Force (NCIJTF), forging partnerships domestically and internationally within governments and the private sector.
His many recognitions include, inter alia: Presidential Rank Award for Meritorious Executive; one of the most influential people in information security by Security Magazine and SC Magazine; Federal 100 Award (twice); McAfee Inc cybercrime fighter of the year etc.
Shawn has lectured at prestigious universities; has held, and currently holds, many high profile directorships; has been a keynote speaker at many major conferences; was a US delegate to the G8; has been interviewed by or contributed extensively to countless television, radio, newspaper segments.
Tamim Ansary
Author, teacher and lecturer
Tamim Ansary is an Afghan American author, teacher, and lecturer who takes a particular interest in zones where cultures and civilisations overlap. His books, which have been translated into over a dozen languages, include West of Kabul, East of New York, a memoir about straddling a cultural fault line in the world; Games Without Rules, a history of Afghanistan from the inside looking out; and Destiny Disrupted, a history of the world through Islamic eyes. His latest work, The Invention of Yesterday, offers a birds' eye view of world history as a fabric woven of cultural narratives and explores how a world historical narrative might be constructed for the global age. Ansary ran the San Francisco Writer Workshop for 22 years and teaches occasionally at the Osher Institute, at U.C. Berkeley.
Tanah Sullivan
Head of Sustainability, GoTo Group
Tanah Sullivan is the Head of Sustainability at GoTo Group. Prior to the merger between Gojek and Tokopedia to form GoTo in May 2021, she led Gojek's sustainability function to accelerate and expand its environmental and social efforts.
Before joining Gojek in 2020, Tanah was at the World Economic Forum in Switzerland, where she led partnerships for a range of sustainability-focused initiatives in ASEAN and globally. She engaged business, government and civil society leaders to work on issues such as energy transition, the circular economy, food security, deforestation and financial inclusion, among others.
Previously, Tanah held various public sector roles at the Canadian and Australian governments, covering international development, natural resource security as well as foreign trade and investment.
Tanah holds a Bachelor's degree in International Relations from Bond University and a Master of Political Economy from the University of Melbourne, Australia.
Tariq Fancy
Former Chief Investment Officer for Sustainable Investing, BlackRock; and Founder, The Rumie Initiative
Born and raised in Toronto, Tariq Fancy began his career in Credit Suisse First Boston's technology-sector investment banking group in Silicon Valley. In 2003, he joined New York-based private equity firm MHR Fund Management, where he became the firm's youngest partner. In 2018, BlackRock hired Tariq as Managing Director and first-ever Chief Investment Officer of Sustainable Investing.
After working at the highest levels in ESG and sustainable investing, Tariq Fancy stunned Wall Street by speaking out on the greenwashing practices in the financial community. Tariq has been featured in The Guardian, The Wall Street Journal, Bloomberg News, The New York Times, among other media outlets.
Tariq now focuses on bringing free learning to children around the world through Rumie. Founded in 2013, Rumie is a non-profit that uses affordable technology to make learning new skills as fun and easy as social media and is used in over 100 countries today.
Tengku Muhammad Taufik
President and Group CEO, PETRONAS
Tengku Muhammad Taufik, a Malaysian aged 47, holds a BA (Honours) Degree in Finance & Accounting from Strathclyde University, Scotland. He is a Fellow of the Institute of Chartered Accountants in England and Wales (ICAEW) and Member of the Malaysian Institute of Accountants (MIA).
Tengku Taufik was appointed as President and Group CEO of PETRONAS in July 2020. He was previously Executive Vice President and Group CFO in 2018. Currently, he holds Board positions in various PETRONAS companies.
He is the Chairman of East Coast Economic Region Development Council (ECERDC) Audit Committee, National Trust Fund and Northern Corridor Implementation Authority (NCIA) Audit Committee, CEO Action Network as well as a Council Member of the ECERDC and NCIA.
Tengku Taufik is also on the Board of Trustees of the Merdeka Award Trust and member of the World Economic Forum (WEF) Oil & Governors Forum, WEF Industry Action Group and APEC Business Advisory Council (ABAC).
Vinesh Sinha
Founder and CEO, FatHopes Energy
Vinesh Sinha is an entrepreneur, investor and environmentalist. He is best known for his role as the founder of FatHopes Energy in 2010. He also started other ventures such as Minenergy and WRMS (Waste Resource Management Software). Recently, he invests in a new business called COOX, a food and beverages industry business incubator.
In 2017, he was the top finalist for the Ernst & Young Entrepreneur of the Year Award for the Emerging Entrepreneur category in Malaysia. He was listed in Forbes 30 under 30 – Asia in 2018 and received The Edge Inspiring Young Leaders Award in 2019.
Sinha enrolled in the London School of Commerce in Business and Finance in 2006. However, he dropped out of college to go into business. In 2019, he completed his tertiary education in the Executive Program, Owners/President Management (OPM56) at Harvard Business School.
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The group gathered in the parlour.
"Thank you for your help, and keeping the entire Universe safe." Cheryl Olive began.
"Oh, it was nothing!" Firetop commented, not exactly sure what he had done.
Beryl looked at Lycralad, who looked away quickly and into the eyes of Adam. He then looked away quickly once again, down to the floor. Adam smiled broadly.
"So Adam was a guardsman?" Lycralad asked, nodding towards Adam.
"As was Ammeloc the Elder," Beryl gestured toward the elderly man, who smiled towards Firetop. "And the banshee" Beryl continued, looking now at Annabeth. Charlie watched as Annabeth changed her appearance, quickly to that of the banshee, before returning to her normal human appearance. She smiled as Charlie jumped slightly in his chair.
"But I found Annabeth the mermaid by chance," Charlie asked, thinking back to the cliff top.
Lycralad looked at Adam. "Shadow is a banshee?" he asked, desperately trying to keep up.
"Ah…" Lycralad thought he understood.
"Think nothing of it…" Lycralad commented, remembering the scripulus.
"Good choice!" He said, giving her a warm hug. She hugged back, starting to feel just a little more human already.
Adam mounted Shadow and waved with a smile as he sped off through the trees into the darkness beyond.
"Helloooooo my sweeeetttt…" the scripulus whispered from behind Sue. Lycralad made a move to run back inside, and Sue stopped him.
"Offff courssseee……" the scripulus replied, "take care of my sweeeetttt…" She took to the skies, and also vanished into the night.
Lycralad and Sue walked over to Igor. Lycralad released him from the tether. "There you go, Igor. You are free once again. Return to your family, and thank you for your help." The wyvern gently rubbed his head into Lycralad's chest before flying away from the cottage.
"I sent him that way." Sue said, with a smile.
"I thought mind control was bad?" Lycralad asked.
Lycralad smiled, as he and Sue joined Firetop and Invisible Charlie in the centre of the lawn.
Beryl, Merrell and Cheryl Olive, and Annabeth, stood before them.
"Thank you for all your help this evening," Cheryl Olive said. Cheryl Olive, Beryl and Merrell then lifted their left hands, and in a flash they, Annabeth and the cottage were gone. In front of the EFB now were the helicopter and the clearing in which they had landed upon their arrival to the island. A couple of wyverns flew overhead.
"Another job well done," Invisible Charlie said, "Let's go home… And Happy Hallowe'en everyone!


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to shine and Elevate, again.
Paula Antonello Moore, Prose. Copyright: Thursday, November 29, 2018.
Thank you Dami. Now if I could only elevate myself 🙂 hope you are well.
Even your encouragement sparkles. 🌟thank you my friend.
Yes – please be elevated, Paula 🙂 Great work.


Remember this fabric I purchased the day I was dismissed from jury duty? I made them into cocktail napkins!
Back in November, I took a napkin sewing class at Picking Daisies and learned how to sew fabric napkins with mitered corners. It was on a Saturday afternoon, and Sean drove out to meet me for lunch. He came into the classroom at the back of the shop just as I was finishing the second napkin.
We went to lunch, and you can guess who picked up the tab.
On a separate note, today's adventure involved driving out to Los Osos to look for the County's community toilet recycling center, to dispose of the old toilet that Sean replaced yesterday.
Here is a photo of Old Broken Wing, posing for the blog at my request. The broken elbow didn't need to be set in a cast because it wasn't a displaced bone, but he is supposed to be wearing a sling on that right arm. Then again, he is supposed to be resting that arm, and not doing things like changing out old toilets and lugging them to recycling centers.
Categories: Handmade | Tags: cocktail napkins, lucha libre, luchador, Morro Bay, Sean, sewing, toilet bowl planters | Permalink.
I've been enjoying your posts daily and even got a bit of a history lesson. I was gonna comment on how it was fitting for Sean to be wearing a Waialua shirt with the toilets cuz I thought the translation of Waialua had something to do with water (wai) and toilets (lua). I did a quick google search and didn't find anything about toilets in the meaning of our li'l town's name! Ha!


text:
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T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence
Laryngology
Pihla Pakkanen ORCID: orcid.org/0000-0002-0009-81461,
Taru Ilmarinen1,
Elina Halme2,
Heikki Irjala3,
Petri Koivunen4,
Matti Pukkila5,
Sami Ventelä3,
Jaana Hagström6,7 &
Leena-Maija Aaltonen1
European Archives of Oto-Rhino-Laryngology volume 278, pages 4863–4869 (2021)Cite this article
We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC).
Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected.
Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate.
The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial.
Trial registration number and date of registration HUS/356/2017 11.12.2017.
T1 glottic laryngeal squamous cell carcinoma (LSCC) can be treated either with trans-oral laser surgery or with radiotherapy. The prognosis is excellent regardless of the treatment method [1,2,3,4,5,6,7,8]. In Finland, LSCC is mainly treated in university hospitals. The Finnish Head and Neck Oncology Working Group gives treatment guidelines for head and neck malignancies, and Multidisciplinary Tumor Board in each university hospital gives treatment recommendations for individual patients. Routine follow-up visits for head and neck cancer patients have been scheduled every 3–6 months during the 1st and 2nd year after treatment, and every 6–12 months thereafter, up to 5 years. However, the follow-up protocol varies between university hospitals, and clinicians may intensify or de-intensify follow-up intervals for individual patients, according to their risk profile.
In T1 glottic LSCC, post-treatment surveillance is primarily aimed at early detection of local recurrence. In recurrent head and neck cancer, the presenting symptoms, the pattern of recurrence (locoregional vs. distant), and options available for further treatment (curative vs. palliative) depend on the primary tumor subsite. The previous studies on post-treatment follow-up typically address all head and neck subsites as a single group [9, 10]. Tumor stage and site have a strong impact on likelihood of recurrence. Thus, similar follow-up protocols may not be applicable for all head and neck subsites. Recurrences of T1 glottic LSCC are typically local, and treatment of recurrent disease is often successful.
The aims of our study were to assess nationwide treatment outcome of T1 glottic cancer, with a special attention on the role of routine follow-up visits in detection of cancer recurrence.
We included all patients diagnosed with stage T1 glottic LSCC in the five Finnish university hospitals between years 2003 and 2015. Data were collected from the National Cancer Registry, and from medical records in each university hospital. The dates of death were collected from the Population Register Center. The study group comprised 303 patients (mean age 67 years, range 29–93), of whom 263 (87%) were male. All study patients were treated with curative intent, either with surgery or with radiotherapy. Transoral endoscopic surgery was the preferred method. Only one patient underwent open surgery. Radiotherapy was conventional external beam radiation therapy or intensity-modulated radiation therapy. The typical total radiation dose was 66 Gy in 2-Gy fractions. The treatment modality of the patients is decided in Multidisciplinary Tumor Board meeting according to the national treatment guidelines by The Finnish Head and Neck Oncology Working Group. The oncological outcome of the surgery and radiotherapy is considered as equal. Hence, function and individual patient-related factors are regarded in the treatment decisions.
Of all 303 patients, 263 (87%) had a minimum follow-up of 3 years, and 205 (68%) of 5 years, or until death. Routine follow-up visits were programmed every 3–6 months during the 1st and 2nd year after treatment, and every 6–12 months until 5 years. Laryngoscopy using a mirror, a fiber-optic endoscope, or a video-endoscope was the method used for clinical examination during follow-up.
Local recurrence was defined as presence of squamous cell carcinoma in biopsy specimen obtained more than 6 months after treatment of primary disease. Positive biopsy specimens obtained less than 6 months after treatment indicated residual, rather than recurrent, disease. Overall survival (OS) was defined as the duration from diagnosis to death from any cause. Recurrence-free survival (RFS) was defined as the duration from diagnosis to the first documented recurrence. Disease-specific survival (DSS) was defined as the duration from diagnosis to the death caused by LSCC.
The Ethics Committee of Surgery in the Hospital District of Helsinki and Uusimaa approved the study. Institutional permissions were granted. According to the Finnish law, informed consent is not required from patients in a retrospective study design.
IBM SPSS Statistics 24.0 was used for statistical analyses. Chi-square and Fisher's tests were used to compare categorical variables, and t test and Mann–Whitney U test to compare continuous variables. Kaplan–Meier method and log-rank test served to compare association between categorical variables and survival. Statistically significant p value was set at 0.05. STROBE reporting guideline followed in this study.
Clinical characteristics
We included 303 patients with T1 glottic LSCC. As expected, the number of patients diagnosed per university hospital (range 24–130) varied according to their population coverage. Of 303 patients, 274 (90%) had stage T1a, and 29 (10%) T1b disease. Table 1 presents clinical characteristics of all study patients.
Table 1 Clinical characteristics of all patients with T1 glottic cancer
In total, 163 (54%) patients were treated with surgery and 140 (46%) with radiotherapy. The proportion of patients treated with surgery (range 13–64%) varied significantly between the five university hospitals (p < 0.001).
Patients with T1b LSCC were more likely to undergo radiotherapy than T1a patients (83% vs. 42%, p < 0.001, respectively). In T1a tumors, involvement of the anterior third of vocal fold did not correlate with the primary treatment method.
Of 163 patients treated primarily with surgery, 11 (7%) had residual tumor which was treated with radiotherapy. Conversely, 2 of 140 (1%) patients primarily treated with radiotherapy had residual tumor which was treated with endoscopic surgery or total laryngectomy and neck dissection. The treatment of T1a patients is presented in the Fig. 1.
Treatment of 274 T1a LSCC patients. The patients who eventually underwent both surgery and radiotherapy are shown in the middle (in italics). RT radiotherapy
In total, 38 of 303 patients (13%) with T1 LSCC developed a recurrence during follow-up (Table 2). Of 38 recurrences, 35 (92%) were local and 3 (8%) regional or distant. The median time between primary LSCC diagnosis and local recurrence was 1.7 years (range 0.6–8.9 years). Of 35 local recurrences, 7 (20%) were diagnosed more than 5 years after primary LSCC diagnosis.
Table 2 Patients with recurrence (n = 38)
Local recurrence rates in T1a (31 of 274, 11%) and T1b (4 of 29, 14%) were similar (p = 0.758). University hospitals had similar local recurrence rates (p = 0.340).
Five-year RFS was 91% in all patients, 91% in T1a patients and 86% in T1b patients. The corresponding numbers for 3 year local control were 92, 92 and 90%. RFSs were not associated with T stage (p = 0.831) in log-rank test. Presence of earlier dysplasia, age at diagnosis or smoking history was not significantly associated with recurrences, laryngeal preservation or second primary tumor.
Local recurrences and primary treatment of T1a glottic cancer
Local recurrence of T1a after primary surgery occurred in 25 of 158 (16%), and after primary radiotherapy in 6 of 116 (5%). Thus, local recurrence of T1a was significantly more likely after surgery than radiotherapy (p = 0.006). However, 5 of 25 (20%) local recurrences of T1a after surgery occurred over 5 years after primary treatment. Five-year local control in T1a was higher after radiotherapy than surgery (97% vs. 87%, p = 0.020).
Resection margins
Positive resection margins were reported in 15 of 158 (9%) T1a patients treated with surgery, and 7 of them underwent re-resection. Local recurrence was detected in 2 of the 7 (29%) re-operated patients during follow-up, and in 3 of 8 (38%) patients without re-operation. Resection margins were defined as negative if they were not infiltrated by tumor cells, or if negative resection surface biopsy specimens were obtained after endoscopic removal of tumor. Negative resection surface margins were reported in 71 of 158 (45%) T1a patients treated with surgery, and 7 of 71 (10%) developed a local recurrence. Resection surface margin status was not reported for 72 (46%) patients. T1a patients with positive resection margins had higher local recurrence rate than patients with negative margins (33% vs. 10%, p = 0.031). Margin status was not associated with DSS in T1a patients (p = 0.064).
Treatment of recurrent T1 glottic cancer
Of all 38 patients with recurrent disease, 14 (37%) underwent radiotherapy, 11 (29%) endoscopic surgery, and 9 (24%) total laryngectomy and/or neck dissection. Total laryngectomy rate was similar in patients primarily treated with surgery (5 of 163, 3%), compared to those treated with radiotherapy (8 of 140, 6%, p = 0.395). Two of 38 (5%) patients had palliative care and died in laryngeal cancer after their first recurrence, and two (5%) patients died of other causes.
The majority of recurrences (26 of 38, 68%) were detected by clinical examination on a routine follow-up visit (Fig. 2). Nine patients (24%) requested a visit because of new symptoms. Two (5%) recurrences were diagnosed during clinical examination of another disease. In one patient (3%), the recurrence was detected by PET imaging, which was part of the follow-up protocol in one university hospital.
Of 38 T1 LSCC recurrences, 26 (68%) were detected on a routine follow-up visit
Over half (21 of 38, 55%) of recurrences were detected in patients presenting without new symptoms. The most common symptom was hoarseness in 13 patients, followed by pain in 3 and dysphagia in 3. The patients primarily treated with radiotherapy reported pain as a symptom of local recurrence more often compared to patients treated with surgery but the difference was not statistically significant (2 of 9 (22%) vs. 1 of 26 (4%)). Sex or age was connected neither with symptoms of local recurrence, nor with detection of local recurrence on a routine visit versus on other visit. Twenty-one of 31 (68%) T1a patient's and 3 of 4 (75%) T1b patients' local recurrences were detected on a routine follow-up visit (p = 1.000). Seventeen (55%) of 31 T1a patients and 3 (75%) of 4 T1b patients with local recurrence were symptomatic (p = 0.619). The time interval from diagnosis to local recurrence in patients presenting with a new symptom was significantly longer, compared to patients without new symptoms (median 2.7 years (range 0.9–8.4 years) vs. median 1.6 years (range 0.6–8.9 years), Mann–Whitney p = 0.019).
The larynx preservation rate was not connected with symptoms of local recurrence, or with detection of local recurrence on a routine follow-up visit. Larynx preservation rate was 60% in the patients with symptomatic local recurrence and 70% in the asymptomatic patients (p = 0.721). Accordingly, 9 of 20 (45%) symptomatic local recurrences and 3 of 15 (20%) asymptomatic local recurrences were treated with trans-oral endoscopic surgery.
Survival of patients with stage T1 glottic cancer and second primary tumors
Of 303 patients, 8 (3%) died of LSCC. Five-year overall survival (OS) of all study patients was 82%, 82% in patients with stage T1a disease and 76% in T1b. The corresponding numbers for 5 year DSS were 98, 97 and 100%. In log-rank test, OS and DSS did not correlate with T stage, university hospital or primary treatment method.
Second primary tumor (either in the head and neck or in the lungs) was diagnosed in 20 of 303 (7%) patients during follow-up. Second primary subsites were lungs (12/20, 60%), hypopharynx (4/20, 20%) and other head and neck subsite or multiple subsites (4/20, 20%). Eight (8/20, 40%) of the second primary tumors were diagnosed concurrently with LSCC, or during LSCC treatment, and 4 (4/20, 20%) more than 5 years after LSCC diagnosis. Of 303 patients, 9 (3%) died of second primary tumor. The primary treatment method was not related to second primary tumors (p = 0.248).
We assessed the treatment outcome and the benefits of routine follow-up in T1 glottic LSCC. In our study, most of the recurrences were local, and 26 of 38 (68%) were diagnosed during a routine follow-up visit. Only 45% of patients had new symptoms when the recurrence was diagnosed. Finland has a publicly funded health care system. The role of routine visits is currently discussed to improve cost-effectiveness of follow-up protocols. According to our study, routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Furthermore, clinical follow-up of LSCC with modern flexible endoscopes is easy and feasible, without causing exposure to radiation.
Our results are similar compared to the study by Ritoe et al. where they included LSCC patients with T stage I to IV. In their study, 122 of 156 (78%) LSCC recurrences and second primary tumors were found within 3 year follow-up, and 94 of 156 (60%) recurrences and second primary tumors were detected on a routine follow-up visit [11]. In another study, 81% (103 of 127) of patients with stage I to IV glottic LSCC who developed a recurrence were symptomatic [12]. In our study of T1 patients, the number of symptomatic patients was substantially lower.
After treatment of T1 glottic LSCC, patients may adapt to often permanent changes in voice quality. Some patients may have hoarse voice due to a large post-surgical glottal gap, or mucosal edema after radiation therapy. The first symptom of local recurrence in these patients may be airway obstruction and stridor. Thus, detecting a recurrence of early glottic LSCC by symptom-directed surveillance only is more complicated compared to some other head and neck cancer subsites, in which the majority of recurrences are detected when new symptoms appear [13]. Early detection of local recurrence allows curative treatment with acceptable oncological and functional outcome. Compared to patients with late recurrences, patients with early (< 2 years) recurrence of T1 LSCC were less likely to present with a new symptom, and less likely to be diagnosed on a patient-requested visit. It may take long for the post-treatment voice problems to resolve, and newly treated patients especially may not recognize subtle changes in voice as a symptom of recurrence. Furthermore, patients may not request for an extra visit because follow-up during the first 2 years is typically intense.
The 5-year RFS and DSS in this study were comparable to the previous review studies [5, 8, 14, 15]. A Finnish nationwide study showed that 5-year RFS in T1a glottic cancer was 88%, and DSS 100%. In T1b glottic cancer, RFS was 82% and DSS 95% [16]. Our previous prospective randomized study of 56 patients showed that T1a glottic LSCC recurred in 11%, already during 2-year follow-up [17].
Five out of 303 (1.7%) patients developed glottic LSCC over 5 years after primary diagnosis. We considered these as recurrences rather than new primary tumors. The definitions of treatment failure, recurrence, and new primary tumor are somewhat controversial. According to the previous literature, late cancer events in LSCC are rare [18]. Prolonged post-treatment follow-up may not be justified in all patients with T1 glottic LSCC. If new symptoms should occur, the threshold for re-examination should be low.
Primary surgery was associated with inferior RFS, compared to primary radiotherapy. Radiotherapy has earlier been the gold standard for T1 LSCC treatment but in surgery a major change occurred after an article by W. Steiner in 1993 [19]. Endoscopic laser surgery of early LSCC was introduced soon also in Finland, and there may have been surgeon-related learning curve effect in the beginning. In addition, possible errors in T-staging could have affected the results. However, we found no association between the primary treatment method and the other outcome measures, such as DSS and OS. Moreover, larynx preservation rate was similar in both treatment methods. Selection of the primary treatment varied significantly between the five university hospitals. Radiotherapy was preferred in university hospitals where the number of patients was smaller. Possibly, in these smaller units, the availability of radiotherapy was better compared to surgery.
Our study represents approximately 60% of T1 LSCC cases diagnosed in Finland between years 2003 and 2015, because patients treated in non-academic centers were not included [16, 20]. Complete follow-up data were unavailable for some patients, since they were treated in the smaller university hospitals, responsible for large geographical areas with long distances. Soon after treatment, these patients were referred to non-academic hospitals for follow-up. Due to the retrospective study design, detailed information was not always available for smoking, previous dysplasia, margin status, and presence of new symptoms in patients presenting with local recurrence.
The National Cancer Database study from the USA assessed positive margin rates in trans-oral laser microsurgery of LSCC. Cases treated at non-academic centers and those with lower caseloads had a higher likelihood of positive margins [21]. Silverman et al. showed that postoperative radiotherapy of T1-T2 LSCC was significantly more common in low-volume centers [22]. In our study, positive margin status in T1a was associated with a higher risk of local recurrence. Furthermore, 11 of 163 (7%) patients primarily treated with surgery had residual tumor, requiring further treatment with radiotherapy. These findings highlight the need for thorough pre-treatment work-up and surgical skill, since bimodal treatment of T1 LSCC should be avoided. In our retrospective study, margin status was unavailable for a large number of patients (46%). The prognostic value of positive margin status, according to the literature, is controversial [23, 24]. A uniform guideline for determining negative resection margins would be useful, and margin status should be considered in upcoming recommendations for clinical follow-up.
Pre-treatment diagnostic work-up is the key element in choosing the optimal treatment modality. RFS was inferior in patients primarily treated with surgery, compared to patients treated with radiation therapy. However, DSS, OS and laryngeal preservation rate were similar. Treatment of T1 glottic LSCC may cause permanent voice changes, and symptoms of local recurrence can be misinterpreted as post-treatment sequelae. Routine post-treatment follow-up of T1 glottic LSCC is beneficial.
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Abdurehim Y, Hua Z, Yasin Y, Xukurhan A, Imam I, Yuqin F (2012) Transoral laser surgery versus radiotherapy: systematic review and meta-analysis for treatment options of T1a glottic cancer. Head Neck 34:23–33
Aydil U, Akmansu M, Kizil Y, Yazici O, Üstün S, Karaloǧlu F et al (2013) An individualised treatment algorithm for tumour stage 1 glottic squamous cell carcinoma. J Laryngol Otol 127:1127–1133
Feng Y, Wang B, Wen S (2011) Laser surgery versus radiotherapy for T1–T2N0 glottic cancer: a meta-analysis. Orl 73:336–342
Jones AS, Fish B, Fenton JE, Husband DJ (2004) The treatment of early laryngeal cancers (T1–T2 No): surgery or irradiation? Head Neck 26:127–135
Warner L, Chudasama J, Kelly CG, Loughran S, Mckenzie K, Wight R et al (2014) Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD002027.pub2
Ahmed J, Ibrahim ASG, Freedman M, Rosow DE (2018) Oncologic outcomes of KTP laser surgery versus radiation for T1 glottic carcinoma. Laryngoscope 128:1052–1056
Ding Y, Wang B (2019) Efficacy of laser surgery versus radiotherapy for treatment of glottic carcinoma: a systematic review and meta-analysis. Lasers Med Sci 34:847–854
Vaculik MF, MacKay CA, Taylor SM, Trites JRB, Hart RD, Rigby MH (2019) Systematic review and meta-analysis of T1 glottic cancer outcomes comparing CO2 transoral laser microsurgery and radiotherapy. J Otolaryngol-Head Neck Surg 48:1–11
Kyto E, Haapio E, Minn H, Irjala H (2019) Critical review of the follow-up protocol for head and neck cancer patients. J Laryngol Otol 133:424–429
Pagh A, Grau C, Overgaard J (2015) A longitudinal study of follow-up activities after curative treatment for head and neck cancer. Acta Oncol 54:813–819
Ritoe SC, Krabbe PFM, Kaanders JHAM, Van Den Hoogen FJA, Verbeek ALM, Marres HAM (2004) Value of routine follow-up for patients cured of laryngeal carcinoma. Cancer 101:1382–1389
Brandstorp-Boesen J, Zätterström U, Evensen JF, Boysen M (2019) Value of patient-reported symptoms in the follow up of patients potentially cured of laryngeal carcinoma. J Laryngol Otol 133:508–514
Ilmarinen T, Keski-Säntti H, Markkanen-Leppänen M, Haapaniemi A, Tapiovaara L, Atula T et al (2019) De-escalation of post-treatment surveillance in oropharyngeal cancer. Head Neck 41:1457–1462
Baird BJ, Sung CK, Beadle BM, Divi V (2018) Treatment of early-stage laryngeal cancer: a comparison of treatment options. Oral Oncol 87:8–16
Guimarães AV, Dedivitis RA, Matos LL, Aires FT, Cernea CR (2018) Comparison between transoral laser surgery and radiotherapy in the treatment of early glottic cancer: a systematic review and meta-analysis. Sci Rep 8:1–7
Haapaniemi A, Koivunen P, Saarilahti K, Kinnunen I, Laranne J, Aaltonen L et al (2016) Laryngeal cancer in Finland: a 5-year follow-up study of 366 patients. Head Neck 38:36–43
Aaltonen LM, Rautiainen N, Sellman J, Saarilahti K, Mäkitie A, Rihkanen H et al (2014) Voice quality after treatment of early vocal cord cancer: a randomized trial comparing laser surgery with radiation therapy. Int J Radiat Oncol Biol Phys 90:255–260
Haapaniemi A, Väisänen J, Atula T, Alho O-P, Mäkitie A, Koivunen P (2017) Predictive factors and treatment outcome of laryngeal carcinoma recurrence. Head Neck 39:555–563
Steiner W (1993) Results of curative laser microsurgery of laryngeal carcinomas. Am J Otolaryngol Neck Med Surg 14:116–121
Finnish Cancer Registry [Internet]. Available from: https://cancerregistry.fi/statistics/cancer-statistics/. Accessed 19 Feb 2019.
Hanna J, Brauer PR, Morse E, Mehra S (2019) Margins in laryngeal squamous cell carcinoma treated with transoral laser microsurgery: a National database study. Otolaryngol-Head Neck Surg 161:986–992
Silverman DA, Zhan KY, Puram SV, Eskander A, Teknos TN, Rocco JW et al (2020) Predictors of postoperative radiation following laser resection in early-stage glottic cancer. Otolaryngol-Head Neck Surg 163:1–8
Fiz I, Koelmel JC, Sittel C (2018) Nature and role of surgical margins in transoral laser microsurgery for early and intermediate glottic cancer. Curr Opin Otolaryngol Head Neck Surg 26:78–83
Jumaily M, Faraji F, Osazuwa-Peters N, Walker RJ, Ward GM (2019) Prognostic significance of surgical margins after transoral laser microsurgery for early-stage glottic squamous cell carcinoma. Oral Oncol 97:105–111
Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds.
Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, P.O. Box 263, 00029, Helsinki, Finland
Pihla Pakkanen, Taru Ilmarinen & Leena-Maija Aaltonen
Department of Otorhinolaryngology-Head and Neck Surgery, University of Tampere and Tampere University Hospital, Tampere, Finland
Elina Halme
Department of Otorhinolaryngology-Head and Neck Surgery, University of Turku and Turku University Hospital, Turku, Finland
Heikki Irjala & Sami Ventelä
Department of Otorhinolaryngology-Head and Neck Surgery, University of Oulu and Oulu University Hospital, Oulu, Finland
Petri Koivunen
Department of Otorhinolaryngology-Head and Neck Surgery, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
Matti Pukkila
Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Jaana Hagström
Department of Oral Pathology and Radiology, University of Turku, Turku, Finland
Pihla Pakkanen
Taru Ilmarinen
Heikki Irjala
Sami Ventelä
Leena-Maija Aaltonen
Study plan, data collecting: L-MA, PP, TI, EH, HI, PK, MP, SV, JH. Data analysis: PP, TI, L-MA. Manuscript drafting: PP, L-MA, TI. All authors critically reviewed and approved the manuscript.
Correspondence to Pihla Pakkanen.
No conflicts of interest.
The study was approved by the ethical committee of the Helsinki Hospital District.
Consent to participate
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Pakkanen, P., Ilmarinen, T., Halme, E. et al. T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence. Eur Arch Otorhinolaryngol 278, 4863–4869 (2021). https://doi.org/10.1007/s00405-021-06983-3
Issue Date: December 2021
Glottic cancer
Early laryngeal cancer
Treatment method
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Philadelphia 76ers center Jahlil Okafor could very well have ended up in Boston had trade talks between the Celtics and 76ers not fallen through before the deadline, according to the Boston Herald.
Celtics general manager Danny Ainge recently revealed the potential trade, though he would not divulge details once trade talks ceased.
Okafor's move to the Celtics would have likely lifted their front court - which consists of Amir Johnson, Kelly Olynyk and Jared Sullinger - and given them another piece to challenge the Cavaliers and Raptors atop the Eastern Conference.
Okafor is averaging 17.1 points and 7.3 rebounds per game. Clearly the Sixers decided it was in their best interest to keep the rookie on their squad, for now.


I was recently invited onto the Church of the Geek podcast by Brian Bennett and Sam Blair to discuss the blog and the book series. We had a great discussion about the intersection of Theology and Pop Culture, and I wanted to share that podcast with you and encourage you to follow Brian and Sam on Twitter @GeekChurch.
You can download the episode on iTunes or simply click here to listen to it.
Thanks again to Brian and Sam for having me on!


Bill Text - SB-1371 Occupational licensing: list.
An act to add Section 41 to the Business and Professions Code, relating to professions and vocations.
SB 1371, as introduced, Morrell. Occupational licensing: list.
Existing law provides for the licensure and regulation of various professions and vocations by state entities, including, but not limited to, the boards, bureaus, and committees in the Department of Consumer Affairs.
This bill would provide a list of certain occupational licenses and would state that it is the purpose of this provision to establish and maintain a complete list of all occupational licenses required by the State of California. The bill would state the intent of the Legislature to continue to update and complete the list of occupational licenses in this section. The bill would require that the list be kept updated by an unspecified entity.
(a) The purpose of this section is to establish and maintain a complete list of all occupational licenses required by the State of California. It is the intent of the Legislature to continue to update and complete the list of occupational licenses in this section. The list in this section shall be updated by ____ whenever a new license is established and posted on a State of California Internet Web site.
(1) The Dental Board of California: dentist.
(2) The Medical Board of California: physician and surgeon; midwife.
(3) The State Board of Optometry: optometrist.
(4) The California State Board of Pharmacy: pharmacist; pharmacies.
(5) The Veterinary Medical Board: veterinarians; veterinary premises.
(6) The California Board of Accountancy: accountant; accounting firms.
(7) The California Architects Board: architect.
(8) The State Board of Barbering and Cosmetology: barber; cosmetologist; establishment.
(9) The Board for Professional Engineers, Land Surveyors, and Geologists: professional engineer; land surveyor; geologist.
(10) The Contractors' State License Board: contractor.
(11) The Bureau for Private Postsecondary Education: private postsecondary educational institutions.
(12) The Bureau of Electronic and Appliance Repair, Home Furnishings, and Thermal Insulation: service dealer; service contractors; home furnishings businesses; thermal insulation manufacturers.
(13) The Board of Registered Nursing: registered nurse; nurse practitioner; public health nurse.
(14) The Board of Behavioral Sciences: licensed clinical social worker; licensed educational psychologist; licensed marriage and family therapist; licensed professional clinical counselor.
(15) The State Athletic Commission: professional boxer; professional martial arts fighter; manager; trainer; second; referee; judge; matchmaker; timekeeper; promoter.
(16) The Cemetery and Funeral Bureau: cemeteries; cemetery manager; cemetery salesperson; broker; crematories; crematory manager; cremated remains disposer; embalmer; funeral director; funeral establishments.
(17) The Bureau of Security and Investigative Services: alarm companies and employees; locksmith companies and locksmiths; private investigator; private patrol operator, security guard, repossession agencies and employees.
(18) The Court Reporters Board of California: certified shorthand reporter.
(19) The Board of Vocational Nursing and Psychiatric Technicians: vocational nurse; psychiatric technician.
(20) The Landscape Architects Technical Committee: landscape architect.
(21) The Bureau of Automotive Repair: automotive repair dealer; brake and lamp adjuster; brake and lamp stations; smog check stations; smog check repair technician.
(22) The Respiratory Care Board of California: respiratory care practitioner.
(23) The Acupuncture Board: acupuncturist.
(24) The Board of Psychology: psychologist.
(25) The California Board of Podiatric Medicine: doctor of podiatric medicine.
(26) The Physical Therapy Board of California: physical therapist.
(27) The Physician Assistant Committee: physician assistant.
(28) The Speech-Language Pathology and Audiology and Hearing Aid Dispensers Board: speech-language pathologist; audiologist; hearing aid dispenser.
(29) The California Board of Occupational Therapy: occupational therapist.
(30) The Osteopathic Medical Board of California: osteopathic physician and surgeon.
(31) The Naturopathic Medicine Committee: naturopathic doctor.
(32) The Dental Hygiene Committee of California: dental hygienist.
(33) The Professional Fiduciaries Bureau: professional fiduciary.
(34) The State Board of Chiropractic Examiners: chiropractor.
(35) The Bureau of Real Estate Appraisers: real estate appraiser.
(36) The Structural Pest Control Board: operator, field representative, applicator.
(2) School nurse services credential.
(9) Life and Disability Insurance Analyst.
(12) Yacht and Ship Broker; Yacht and Ship Salesperson.
(13) Real estate broker; real estate sales person; mortgage loan originator.


The Inn features five cozy and beautifully appointed rooms conveniently outfitted with modern amenities such as its own kitchen and laundry that make The Ublu Inn ideal for both short and long-term stays. The Inn also features the Kuugaq Cafe within the same building. Visit www.theubluinn.com or give us a call to book your stay.


The 'Paloma' Veil is the definition of exquisite. For the bride who loves unique and romantic designs with the finest attention to detail. This veil is a special piece that will turn heads and become a cherished heirloom. This beautiful handcrafted veil with blusher features delicate tulle with embroidered flowers and butterflies in a stunning pattern with crystal look sequins. Be unlike any other bride in this whimsical and showstopping veil. Only available in ivory.
3 metres / 118 inches in length.


Cell force measurements in 3D microfabricated environments based on compliant cantilevers.
We report the fabrication, functionalization and testing of microdevices for cell culture and cell traction force measurements in three-dimensions (3D). The devices are composed of bent cantilevers patterned with cell-adhesive spots not lying on the same plane, and thus suspending cells in 3D. The cantilevers are soft enough to undergo micrometric deflections when cells pull on them, allowing cell forces to be measured by means of optical microscopy. Since individual cantilevers are mechanically independent of each other, cell traction forces are determined directly from cantilever deflections. This proves the potential of these new devices as a tool for the quantification of cell mechanics in a system with well-defined 3D geometry and mechanical properties.


text:
Understanding Etta
Imaginary Wish List: Etta James
Despite battling a grave drug addiction, American singer Etta James (born Jamesetta Hawkins) released multiple hit singles and albums, and won four Grammys throughout her varied career. Her style of singing was hard to categorize: she started out as a gospel prodigy, and moved onto jazz, blues and pop, constantly displaying a dextrous ability to make each genre work for her unmistakably earthy voice. Signed to Chess Records in 1960—alongside Chuck Berry and Muddy Waters—James quickly established herself as the label's first major female star with a string of hits that very same year. Among her best-known songs are "At Last", "I'd Rather Go Blind" and "A Sunday Kind Of Love", which have since been reimagined by various artists, such as Beyoncé and Cyndi Lauper. Of her art, Etta James famously told The Los Angeles Times in 1992: "A lot of people think the blues is depressing, but that's not the blues I'm singing. When I'm singing blues, I'm singing life. People that can't stand to listen to the blues, they've got to be phonies." In honour of Etta James's soulful talent, here's what we imagine she might pick to wear on stage now.
By Charlotte Sutherland-Hawes
House Of Fame LLC
Atelier Swarovski by Christopher Kane hoops (£199)
Michael Lo Sordo gown (£860)
Tom Ford Lip Lacquer in Copper Chic (£40)
Marina Rinaldi jacket (£919)
Benefit Ka-BROW! eyebrow gel (£20.50)


Chilliwack-based students, take note: the BC Ministry of Science and Universities has announced that it will provide UFV with an additional $10 million in support of its current capital development project. According to the university's December 16 press release, the new funding will go towards ongoing construction costs associated with the renovation and expansion of UFV's facilities at the Canada Education Park (CEP) campus in Chilliwack.
Chilliwack-based students, take note: the BC Ministry of Science and Universities has announced that it will provide UFV with an additional $10 million in support of its current capital development project.
According to the university's December 16 press release, the new funding will go towards ongoing construction costs associated with the renovation and expansion of UFV's facilities at the Canada Education Park (CEP) campus in Chilliwack.
The announcement comes at a crucial time for the CEP after the recent demise of a purchase plan for UFV's downtown Chilliwack campus put forward by Vancouver-based developer Shape Properties.
UFV Development Coordinator Craig Toews said that the new funding will help keep the project on track without having to cut any of the essential pieces.
The Canada Education Park project is a joint venture between UFV, the Justice Institute of BC, the City of Chilliwack, and the provincial government to redevelop the former Canadian Forces Base in Chilliwack into a multipurpose education and research park.
In addition to housing UFV's Trades and Technologies Centre, the current phase of the CEP development project will include room to grow for Health Sciences, Teacher Education, and Aboriginal programming.
Toews emphasized the university's effort to create a space that would foster community spirit and provide students with better places to gather than those of UFV's downtown Chilliwack campus.
One of the ways that the new campus will attempt to remedy this problem is with the creation of an Aboriginal Gathering Place, a large assembly area modelled after a longhouse with a 200 person capacity that will serve both students and the aboriginal community in Chilliwack. Bethany Wiens, a third-year Nursing student at UFV's Chilliwack North campus said that students are looking forward to a new learning environment with better facilities and technology to assist them in preparing for their careers.
UFV student Jay Mitchell said that by expanding UFV's trades and professional programs capacity, the university will continue to grow in a way that serves the Fraser Valley, fulfilling its mandate as a regional university.
MLA John Les noted that the CEP will help boost the local workplace market, creating jobs both during construction and day-to-day campus operations.
In October 2010, UFV awarded the majority of the construction work to BC contractor Stewart Olsen Dominion, who subcontracts to a number of small, local companies.
"Universities," said Les, "are great employers of professors, faculty, and support staff." According to the MLA, the expansion of UFV's facilities in Chilliwack might also favourably influence the pending decision to expand public transit connecting the communities of the Fraser Valley.
However, some students are sceptical that the expansion will result in any real changes to the transit system.
Construction is already well-underway for the $40 million campus development project that broke ground in April 2009. With an anticipated completion date of December of this year, Craig Toews said that the university is looking at a variety of other development projects for the future, including picking up where they left off with the student centre in Abbotsford after funding fell through this past October.
In addition to its recent $10 million investment, the B.C. government has already provided UFV $7.5 million for the purchase of the 84-acre site, $600 000 for the construction of an Aboriginal Gathering Place, and $21.6 million for the renovation of Building 1040, UFV's new Trades and Technologies Centre.


Watu Klotok Temple is a 10th century Balinese Hindu temple in the coastal village of Tojan, in the Klungkung regency of East Bali. This beachfront temple dates to the time of the historic high priest Mpu Kuturan, but is set within a site that itself is believed to date back to the megalithic ages. The temple overlooks Watu Klotok Beach, a stretch of black and pebbly sand that's bordered by the verdant rice fields of a neighboring farming village. You can reach the temple and beach after a scenic kilometre-long drive past these paddies from the Jalan Bypass Ida Bagus Mantra highway.
When there aren't any pilgrims attending for prayers or during Galungan (a major Balinese Hindu observance that occurs every 210 days on the Balinese 'Pawukon' calendar), both Watu Klotok Temple and Watu Klotok Beach are mostly quiet without much going on. It does, however, provide you with a unique kind of sightseeing experience with an exotic beach and cultural landmark sharing the same site. Come weekends, the beach is often a favourite spot for residents to unwind and take in the sunset views.
On clear days, from the temple courtyard you're usually provided with beautiful paddy views with the outlines of Mount Agung, Bali's highest peak, as backdrop. The crashing waves of the Indian Ocean behind you provide the perfect soundtrack to the beautiful scenery. Some of the locals make a living from handicrafts created using gravel and pebbles sourced from the beach as ornamental features for pots, floor tiles and terracotta. If you're feeling peckish and you'd like to try out some local traditional fare, try the fish satay prepared in the Balinese wrap style, called 'sate lilit'.


Loren Long began his children's publishing career as the illustrator of books by authors with familiar names, among them Madonna's Mr. Peabody's Apples and Angela Johnson's I Dream of Trains, Walt Whitman's When I Heard the Learn'd Astronomer, Watty Piper's The Little Engine That Could and Randall de Sève's Toy Boat. Winner of two Golden Kite Awards, Long quickly became a familiar name in the industry in his own right. His debut solo picture book, Drummer Boy, is out from Philomel, which will publish his newest picture book, Otis. Bookshelf spoke with Long about his latest book, which tells the story of the friendship between a caring old tractor and a needy young calf, and about factors that have influenced his work.
Otis has a classic, playful feel. What inspired the look of this art?
Well, to back up a bit, The Little Engine That Could marked a new direction for me, from the standpoint that this was the first book where I was obviously digging into a tried and true classic. I'm very proud of the books I did beforehand, but The Little Engine That Could opened up a new world for me.
The approach I took in Mr. Peabody's Apples and I Dream of Trains was more one of conventional realism. I am a huge fan of the American regionalist painters, the WPA muralists and N.C. Wyeth, and before The Little Engine That Could I never viewed myself as someone who would paint appealing trains with eyeballs and cute little purple elephants and toys. For the first time, I began realizing who my ultimate audience is: little children who would actually be holding one of my books. This was an epiphany for me. I suddenly realized that this is my career, that this is what I want to do for the rest of my life. And I started thinking about the classics that I liked as a child. The Little Engine That Could was a favorite, as was The Poky Little Puppy, The Story of Ferdinand and Virginia Lee Burton's books. I began thinking about creating books that, like these, might someday become a child's favorite, become classics.
So that led to the retro feel of Otis?
Yes, I know it's a warm and fuzzy, maybe corny thought, but that is what I was thinking when I did Otis. I know you can't set out to create a classic—only time will tell that. And who am I to think I can create a classic? It's too assuming, too arrogant to think that. What I did was set out to do a book that has what I think of as classic elements—by those I mean warm, appealing characters and a fun reading experience not only for a child but for adults reading it to them. I want it to be an experience that not only entertains, but gives readers comfort, security and happiness.
And why did you choose to center the story on a tractor and a calf?
I've always kind of liked tractors, and I thought a tractor would make a fun character, one that is rambunctious yet noble. I think The Little Engine That Could inspired part of the book, since Otis, like the engine, is a living, breathing character with emotions. People have asked me why I paired up a piece of machinery with a little animal. I like the fact that this unlikely pair becomes best friends. I'm not attempting to make any kind of statement, other than to show what it means to be a loyal friend and to have empathy and care for another.
With your illustration background, did you first envision the art for Otis and then write the text, or did you create the two simultaneously?
The story and characters were in place before the art. I knew I had to nail the characters first and make them appealing and endearing. I didn't think about what the landscape would be like before I had the story in place. After my editor, Patricia Lee Gauch, accepted Otis, we put it aside and decided to publish it down the road. I then turned my attention to other things, including Jon Scieszka's Trucktown series, which I worked on with Jon, David Shannon and David Gordon. And after working with those knuckleheads—and I say that with all due affection!—I decided that there was a little bit more I could add to Otis to improve it. And that's when I added more of the fun and feistiness.
Is creating your own book—words and art—a different challenge than illustrating stories by others?
I'd say I approach both enthusiastically. If I'm going to illustrate a manuscript that someone else has written, it's got to be something that I love. I remember after getting over the jitters about illustrating a classic like The Little Engine That Could, I cleared off my desk and said, "OK, I love this story enough to do it and make it mine." I hope that doesn't sound overly egotistical. But I feel that the book becomes as much mine as the author's, and as much the author's as mine.
Several books you illustrated reached bestsellers lists and you've won numerous awards. Did that give you a boost of confidence right out of the gate?
Actually it did. It was a bit of a baptism by fire. Some people said I'd become an overnight hit or whatever, and I didn't really have an answer to that. I'd worked for about a dozen years after getting out of school, doing illustrations for greeting cards, theater posters and magazines. But you never meet your audience when you do a picture for a magazine and it's not really the product—you're just decorating the product. But in book publishing, the book is the product. After illustrating my first book, I knew I loved children's publishing right away. I discovered that people cared—teachers, librarians, booksellers and kids. And I got to meet my audience.
Yeah! It was like, "Whoa!" The best compliment I ever got was from my nephew, Luke. He was 10 months old at the time The Little Engine That Could came out and he'd just learned to walk. At a family Christmas gathering, he kept taking the book from grownup to grownup, climbing from one lap to the next, wanting everyone to read it to him. I asked my wife, "He doesn't know that I illustrated this book, does he?" It was very special.
Speaking of youngsters, have your own sons provided input into or inspired your work?
They definitely have. They're 11 and 13 now, and I've always read them the texts I've written and read them manuscripts written by someone else that I'm considering illustrating. They are a good gauge of the fun element and are great sounding boards: is this fun or is this boring? is this character appealing or lame?
Were they on board with Otis from the start?
Actually, Otis started as a story my wife and sons made up as she took them to school when they were preschoolers. It was a homespun story that was more convoluted and took a totally different direction than my book. Now my 13-year-old teases me a bit and says I took their story, tweaked it and called it my own. But then I remind him that it's good to be able to buy groceries and soccer cleats.
Oh yes, there is college. Maybe it's a good thing to contribute to Daddy's work! If it's a family effort, all the better. I'll definitely take it!


(Sacramento, CA- June 3, 2016) On Wednesday, May 25th, Transfer Flow, Inc. was honored by Assemblyman James Gallagher at California Small Business Day. As Small Business of the Year for the Third Assembly District, Transfer Flow, Inc. was celebrated for their hard work and dedication to the community.
California Small Business Day honored 85 small businesses for their contribution to the state's economy. Small business contributes to 75% of California's gross state product and over half of the state's private sector jobs. From hardware stores to manufacturers, small businesses are engrained in California's communities and economy.
The Transfer Flow story began in 1983 in the beautiful and historic town of Chico, California, when former General Motors engineer Bill Gaines, along with his wife Jeanne, founded the company as an OEM fuel system supplier for the motorhome and travel trailer industry.
The business quickly expanded into the mobility, work body, and mainstream automotive industries, and by 1994 the company relocated to a 35,000 square foot manufacturing facility as demand continued to grow. Six years later, a 20,000 square foot building was built on an adjacent 3-acre parcel, and finally in 2008, a 15,000 square foot warehouse was added.
Today, Transfer Flow continues to invest in new technology and state-of- the art manufacturing equipment, while employing a dedicated and hardworking staff of more than 90 people from across Northern California.


text:
Playlist: Woodstock Remembered
You were there, right? August 15-18 marks 40 years since the original Woodstock Music & Art Fair.
Browse specials that are two minutes to two hours and include archival and new interviews, plus recordings from the festival. Producers include Joyride Media, Paul Ingles, Peter Bochan, and more.
Back To The Garden: Woodstock Remembered (2 x 59:00 or 2 x 54:00)
From Paul Ingles | 01:57:40
Musicians and audience members recall the festival that rocked the world. This two-hour special features interviews with Woodstock organizers, plus archival recordings from performers such as Jefferson Airplane, The Who, Richie Havens, and many more.
Back To The Garden: Woodstock Remembered (2 x ...
Paul Ingles
Woodstock organizers, musicians and audience members recall the 1969 music festival that rocked the world in more ways than one. Music and memories from the historic event include interviews with with Woodstock organizers Michael Lang, Joel Rosenman, and the late John Roberts, artists Richie Havens, Roger Daltrey and Joe Cocker, and audience members Ron Petras, Vivian Goodman and Danny Diamond. Music performances from many of the artists are featured: Jefferson Airplane, Creedence Clearwater Revival, Joe Cocker, CSNY, The Who, Arlo Guthrie, Joan Baez and many more.
Hours can be run consecutively or on successive nights or weekends with appropriate tagging and promotion.
Produced by Paul Ingles in association with Joel Makower, author of Woodstock: The Oral History from SUNY Press (available July 9, 2009).
Back To The Garden: Woodstock Remembered (2 x ... | 01:57:40
A Shortcut Back To 1969
From Woodstock to Altamont, Washington to Vietnam, Chappaquidick to Chicago with stops at Stonewall, Hyde Park, Shea Stadium, The Super Bowl, Memphis, Times Square, Sesame Street, and the Moon.
Featuring commentary from John Lennon & Yoko Ono, Iggy Pop, the Smothers Brothers, The Firesign Theater, Monty Python, Richard Pryor, Mick Jagger, Keith Richards, Brian Jones, Roman Polanski, Richard Nixon, JFK, Buzz Aldren, Neil Armstrong, and more.
1969-From Woodstock to Altamont, Washington to Vietnam, Chappaquidick to Chicago with stops at Stonewall,
Hyde Park, Shea Stadium, The Super Bowl, Memphis, Times Square, Sesame Street, and the Moon. Featuring commentary from John Lennon & Yoko Ono, Iggy Pop, the Smothers Brothers, The Firesign Theater, Monty Python, Richard Pryor, Mick Jagger, Keith Richards, Brian Jones, Roman Polanski, Richard Nixon, JFK, Buzz Aldren, Neil Armstrong, Walter Cronkite, Ted Kennedy, Burgess Meredith, Donald Sutherland, Elliot Gould, Dennis Hopper, Jack Nicholson, Peter Fonda, Dustin Hoffman, Michael Lang, "Topaz Caucasion", Chip Monck, Dave Marsh, Joe Boyd, Rob Kirkpatrick, Carl Capotorto, Arlo Guthrie, Hugh Romney, Harry Reasoner, Nile Rogers, various FBI and police agents, The Black Panthers, The Weather Underground, The Zodiac Killer, Apollo 11 astronauts and many others. Music from Hair, Midnight Cowboy, Sly and the Family Stone, The 5th Dimension, Elvis Presley, The Rolling Stones, James Brown, David Bowie, The Who, Les McCann & Eddie Harris, The Beatles, Bob Dylan, Blind Faith, Roy Budd, The Plastic Ono Band, The Jefferson Airplane, Arlo Guthrie, Canned Heat, The Beach Boys, Crosby, Stills, Nash & Young, Joni Mitchell, Beautiful People, Jimi Hendrix, Procol Harum, Henry Mancini and The Stooges!
"Give Peace A Chance!"
A Shortcut Back To 1969 | 55:31
From WXPN | Part of the Black History Month: Profiles in Music series | 04:10
Folk artist Richie Havens is best known for his marathon performance at Woodstock. In this profile, hosted by David Dye, Richie Havens talks about his early influences and performing socially conscious music.
WXPN
See series description
Richie Havens | 04:10
WOODSTOCK - 2 MINUTES OF PEACE & MUSIC
From Joyride Media | 40:00
Twenty modules in honor of Woodstock's 40th anniversary. Each piece includes a mix of live Woodstock music. Segments include exclusive and archival interviews with musicians and others involved with the original festival, including producers Michael Lang and Joel Rosenman, Richie Havens, Paul Kantner, Santana, Graham Nash, Eddie Kramer, and Rose Stone & Larry Graham from Sly & The Family Stone.
Joyride Media
Joyride Media will produce twenty 2 MINUTES OF PEACE & MUSIC modules in honor of Woodstock's 40th anniversary. Each piece will inlcude a mix of live Woodstock music, including clips of many previously unreleased performances. Segments will also include exclusive and archival interviews with musicians and others involved with the original festival, including producers Michael Lang and Joel Rosenman, Richie Havens, Paul Kantner, Santana, Graham Nash, Eddie Kramer, and Rose Stone & Larry Graham from Sly & The Family Stone.
These modules will be great for on-air use around airplay of music by Woodstock artists, during pledge drives, or any way you regularly use 2:00 features. They will also be available as podcasts for your website.
Host Eric Chase was co-producer in 1979 of the 6-hour documentary "Woodstock: 10 Years Later," source of some interview material for this series. More information on that series can be found at http://www.eccsvox.com.
Any feedback would be greatly appreciated. Feel free to contact andy.cahn@publicmediaservice.org with any comments.
#16 is missing due to an error. It will be replaced when fixed.
WOODSTOCK - 2 MINUTES OF PEACE & MUSIC | 40:00
Two Miles From Bethel -- On the Road, well, "almost," to Woodstock!
From Binnie Klein | 08:50
There are many stories of those who made it to Woodstock, and those who never went. What about those who, well, "almost" made it?
Binnie and Anne, two college girls, start out on the road to become a part of history, but a child's worry about a parent's car unexpectedly changes all that.
Two Miles From Bethel -- On the Road, well, ...
Binnie Klein
As we commemorate the 40th anniversary of the Woodstock Festival, there are many stories of those who went, those who never went, but what about those who, well "amost" made it? Binnie and Anne, 2 college girls, start out on the road to become a part of history, but a child's worry about a parent's car unexpectedly changes all that.
Two Miles From Bethel -- On the Road, well, ... | 08:50
Woodstock 40th Anniversary on FM Odyssey
From FM Odyssey | 01:57:53
Fred Migliore is joined by legendary NY radio personality, Pete Fornatale, whose new book "Back To The Garden" provides insight to Woodstock. Original interviews include Joe Cocker, Stephen Stills John Sebastian, Country Joe and Richie Havens.
FM Odyssey
"What sets this show apart from other celebrations of Woodstock is that it brings to life pieces of Woodstock history that few people know." - Fred Migliore
FM Odyssey has been going strong for 18 years and is heard weekly on 37 FM stations in the U.S. and abroad. Host/creator/producer Fred Migliore is pleased to announce the availability of another exciting FM Odyssey event, The Woodstock 40th Anniversary program.
Featured will be the legendary New York radio personality, Pete Fornatale. His new book, "Back to the Garden", published by Simon and Schuster, provides incredible insight for this two-hour journey.
The show will include original interview recollections from many of the headliners who appeared at Woodstock, such as Alvin Lee (10 Years After), Richie Havens, Joe Cocker, Country Joe McDonald, John Sebastian, Joan Baez, Leslie West, and Stephen Stills.
The program also recounts the stories from the cast of characters who worked endlessly behind the scenes to put the concert together, and for those three days, overcame setback after setback to pull it off. There are highlights from an interview an interview Fred did with Duke Devlin, the site interpreter at the Bethel Woods Museum that sits on the original Woodstock site, and of course, plenty of great music.
Sponsored by: The Museum at Bethel Woods Center for the Arts, NY, Yaktivate.com and Florida Institue of Technolgy..
Sponsored by: The Museum at Bethel Woods Center for the Arts, NY, Yaktivate.com and Florida Institue of Technolgy
Woodstock 40th Anniversary on FM Odyssey | 01:57:53