text:
Dwight McNeil- Wiki, Age, Girlfriend, Ethnicity, Net Worth, Height, Career
Dwight McNeil is an English professional footballer. Dwight McNeil is also a winger for Premier League club Everton. He was born in England but due to family ties he is eligible to play for Jamaica.
First and last name:
Horoscope:
Best Match For Marriage:
Leo, Aquarius
Net value
$1 million – $10 million
Oasis Academy
Matty McNeil
Tracy McNeil
Baillie and Chiara
Dwight McNeil Biography
Dwight James Matthew McNeil, better known as Dwight McNeil, was born in Rochdale, England, on November 22, 1999. According to his date of birth, he is 22 years old and of English nationality. Furthermore, he was born under the sign of Sagittarius and is a Christian.
He is also Matty McNeil (father) and Tracy McNeil (mother). His father played professional football for Macclesfield Town and Stockport County in the English Football League. Furthermore, he has two siblings named Baillie and Chiara.
Dwight McNeil Education
In terms of education, he attended the Oasis Academy in Oldham. Apart from that, there is no information about his graduation.
Dwight McNeil Height and Weight
This football player is 1.80 meters tall and weighs about 71 kg. Furthermore, he has dark brown eyes and black hair and has not released any information about his body measurements such as biceps size, hip size, waist size, shoe size and so on.
Dwight McNeil in a game (Source: Pinterest)
As for his career, Dwight McNeil started playing football at Trafford's JJB Sports Center. He joined Manchester United's academy when he was five, the team he supported as a child, and stayed until he was 14 and was released.
In 2014, he joined Burnley's youth team. Likewise, in July 2016, he was offered a two-year scholarship and joined the U18 team and the Development Squad.
In February 2018, he traveled with the selection of the first team, but was not in the match selection. After receiving his scholarship on April 10, 2018, he signed a two-year contract with the club.
After going through Burnley's youth system, he made his first-team debut against Bournemouth on 13 May 2018.
On December 30, 2018, he scored his first goal for the club against West Ham. In 26 games, he scored three goals and provided five assists. In 40 games, he scored two goals and assisted six others.
On October 16, 2020, he extended his Burnley contract until 2024. In 40 appearances for the team in 2020-21, he had 5 assists and 2 goals. This player made 40 appearances and had 1 assist in 2021-22. On 28 July 2022, he signed a five-year deal with Everton for a rumored £20 million plus add-ons.
This young player has represented England. He played for the England U20 and U21 teams. In March 2019, he was called up to the England U21 team for matches against Poland and Portugal.
On March 21, 2019, he made his England U20 debut against Poland U20. This player was included in the U20 team for the Toulon tournament in May 2019 and scored his first goal on June 11, 2019.
He played for England U21 on 30 August 2019. This player made his England U21 debut on October 11 in Maribor against Slovenia.
Dwight McNeil Awards
He has received a number of awards and recognition as a professional football player. He was second in Most Valuable Championship Players, third in Best Championship Players and ninth in Most Valuable Classic Wingers.
Net Worth of Dwight McNeil
Officially, this football star has not disclosed his net worth, salary or income. According to some online media, his net worth is estimated at between $1 million and $10 million with his current club paying him £3.7 million a year.
Dwight McNeil Girlfriend, Dating
Dwight McNeil is too young to get married, according to his relationship status. Since there are no reports or rumors of him dating anyone, this man is currently believed to be single.
He has also not revealed any information about his romantic interests or dating history. He has not posted any pictures of himself with girls on his social media profiles. Moreover, he seems to be more concerned with his career than with finding love.
1 Quick Facts
2 Dwight McNeil Biography
3 Dwight McNeil Education
4 Dwight McNeil Height and Weight
6 Dwight McNeil Awards
7 Net Worth of Dwight McNeil
8 Dwight McNeil Girlfriend, Dating
Previous articleFinancial Offers for Reliance Capital Must Be Submitted Monday
Next articleUntold truth about the "insatiable" star
Lenny Nicholson: Untold details about Amerie's husband
Lenny Nicholson is a talent manager widely recognized as the husband of an American singer Amerie (aka Amerie Mi Marie Nicholson). His wife...
Austin Stoermer Coleman – Wiki, Bio, Age, Net Worth, Parents
Austin Stoermer Coleman is an emerging American actor and media personality who has appeared in a number of films and television series. He...
What is Evan Felker doing now? Where is Evan Felker today?
 Who is Evan Felker?Evan Duane Felker was born on March 24, 1984 in Okemah, Oklahoma, USA. He is...
1 Dwight McNeil- Wiki, Age, Girlfriend, Ethnicity, Net Worth, Height, Career
1.2 Quick Facts
1.3 Dwight McNeil Biography
1.4 Dwight McNeil Education
1.5 Dwight McNeil Height and Weight
1.6 Career
1.7 Dwight McNeil Awards
1.8 Net Worth of Dwight McNeil
1.9 Dwight McNeil Girlfriend, Dating
1.9.1 Lenny Nicholson: Untold details about Amerie's husband
1.9.2 Austin Stoermer Coleman – Wiki, Bio, Age, Net Worth, Parents
1.9.3 What is Evan Felker doing now? Where is Evan Felker today?


text:
Robert A.M. Stern: Houses
Published by: New York: The Monacelli Press, 1997
In over thirty years of practice, Robert A. M. Stern has developed a distinctive architecture committed to the synthesis of tradition and innovation and, above all, to the creation and enhancement of a meaningful sense of place. Inspired by the great legacy of American architecture, the firm of Robert A. M. Stern Architects has produced a variety of building types in a range of stylistic vocabularies. The design of houses, for which the firm initially gained notice, remains a cornerstone of the practice. Beautifully illustrated in color, this major monograph – a companion volume to the best-selling Robert A. M. Stern: Buildings – thoroughly documents more than forty-five houses built over the course of thirty years.
Open Studio: The Work of Robert A.M. Stern Architects

redpajama_set_name: RedPajamaCommonCrawl


text:
Tag Archives: Japanese character
This years kanji
Every December a 漢字 (Japanese kanji character) is chosen in Japan that best summarizes the year that is ending…and it becomes the official 「今年の漢字」 ("Kanji of the Year") in a ceremony in Kyoto with the temple monk writing the character in calligraphy brushstrokes on a large board.
The 2011 Kanji of the Year is 「絆」 ("Bond").
The official character for 2011 was announced today. It's 「絆」 (Kizuna)…which means "(to) bond".
This was chosen because of the way the people of Japan and the world came together to help the victims of the March 11 earthquake.
(Last year (2010), the Kanji of the Year meant "hot". Click here to find out why.)
Tags: きずな, bond, 絆, earthquake, Japan, Japanese, Japanese character, kanji, kanji of the year, kizuna, kyoto, March 11, Tokyo
Categories Events, festivals, Japan, My kids
カッパさん
Let me introduce you to a Japanese folklore character.
Do you know what a 「カッパ」 ("Kappa") is?
It's a fictional character that has been a famous folklore legend in Japan for centuries.
It looks like a creepy turtle-like creature with a "dish" on it's head surrounded by hair, a turtle-like shell on it's back, a bird-like beak and webbed fingers and toes.
It lives in the rivers, streams and other bodies of water in Japan.
Kappa love to eat cucumbers. So there is a type of sushi made with cucumber that is called "Kappa-maki".
But their favorite meal is children. They like to eat children who wander too close to rivers and streams.
As you may have guessed, the "Kappa" is a type of "boogey-man" in Japan that is meant to frighten children from playing too close to water were they might drown.
That's the purpose of Kappa. To keep small children from playing near rivers and streams.
So, almost every sign near rivers, streams, ponds, etc that warn children from playing there have a picture of a Kappa.
The character is basically a "do not swim" mascot.
The sign says "Danger!! Don't play in the water" (The faded blue sign says about the same)
(Signs in Japan for earthquake shelters have a logo too. A catfish. (I wrote a post about that: here).
Kappa can be seen many places in Japan. There's even a part of Tokyo called 合羽橋 (Kappabashi).
The Kappa has a weak point.
His incredible strength stems from the "dish" on top of his head that is full of water.
Kappa must be careful to never let the water spill out of the dish.
But the Kappa is famously polite…if a person is confronted by a Kappa that person should bow to the Kappa because the polite Kappa will surely return the bow—and then spill the water off his head which would render him helpless.
And there's another weakness…if someone refills a Kappa's empty "dish" and restores his strength, the Kappa will be indebted to that person for life.
A cuter Kappa-san
What types of folklore creatures are in your country's culture? And they meant to ensure children's safety, like the Kappa?
Tags: かっぱ, カッパ, danger, Japan, Japanese, Japanese character, Japanese creature, Japanese folklore, Japanese legend, Japanese monster, Kappa, Kappa-san, Kappabashi, 河童
Categories Japan
"New" Kanji of the Year
Every December a kanji character is chosen in Japan that represents the year that coming to an end, and the character is written in traditional 習字 (calligraphy) by the head monk at a temple in Kyoto and presented in a ceremony to the public.
Last year (2008), the character 「変」 ("change") was chosen. Click here to read my post from last year to see why that character was chosen.
It was decided that since the U.S. elected a historic new President, Japan elected a Prime Minister from a new party, and also because of the global epidemic of "Swine Flu" which is called 「新型インフルエンザ」 ("New Flu") in Japan…that the kanji character for 2009 is 「新」, which means "new".
The 2009 Kanji of the year is the character for "New"
Here's a picture of the head monk writing the character 「新」 ("new") in traditional Japanese calligraphy:
Tags: atarashii, Buddhist, calligraphy, 習字, Hatoyama, Japan, Japanese, Japanese character, kanji, kanji of the year, kyoto, monk, new, New Flu, obama, Prime Minister Hatoyama, shin, Swine flu, temple, Tokyo, traditional calligraphy, U.S. President Obama, 新, 新型インフルエンザ, 東京, 京都, 漢字
Categories Events, Japan, kyoto, News
Yesterday was my oldest daughter's 中学校の卒業式 (Junior High School graduation ceremony).
After Spring vacation she'll start her first year of high school (10th grade). I can't believe how fast my kids are growing up!
Today is 春分の日 (Spring Equinox). (Click here to read my short FAQ about this holiday).
In Japan, both 春分の日 (Spring Equinox) in March and 秋分の日 (Autumn Equinox) in September are holidays, so we have the day off…and they're days that many people pay a visit to their family gravesite.
So, this morning we went to our family gravesite to leave flowers and pay respects. It's called 墓参り (Haka-mairi).
After that, we went to the 「アンパンマンとやなせたかし展」 ("Anpanman & Takashi Yanase Exhibit") at the 日本橋三越本店 (Mitsukoshi Dep't Store head store in Nihonbashi, Tokyo).
やなせ・たかし (Takashi Yanase) is the artist who created the famous and extremely popular children's cartoon character アンパンマン (Anpanman).
This exhibit at the 日本橋三越本店 (Mitsukoshi Dep't Store head store in Nihonbashi, Tokyo) is to celebrate やなせ・たかし (Takashi Yanase)'s 60 years of being an artist, the 40th anniversary of the アンパンマン (Anpanman) comic, and the 20th anniversary of the アンパンマン (Anpanman) TV series.
アンパンマン (Anpanman) is about as popular as Mickey Mouse is in Japan. Maybe more.
アンパンマン (Anpanman) is a superhero whose head is made of Anpan, which is a sweet-bean filled bun.
He and his friends (most of whom also have heads made of various types of bread or some other healthy food) fight 「ばいきんまん」 (Germ man) and his partner 「どきんちゃん」 (Dokin-chan) who use various inventions and their army of 「かびるんるん」 (Mildew maniacs) to try and fill the world with germs.
アンパンマン (Anpanman)'s weakness is if his head becomes wet…at which he's helpless until the friendly baker 「ジャムおじさん」 (Jam-ojisan) makes a new head for him.
「ばいきんまん」 (Germ man)'s weakness is contact with soap.
There are also sub-plots in the story which include:
「どきんちゃん」 (Dokin-chan)'s having an infatuation with アンパンマン (Anpanman)'s friend 「食パンマン」 (Sandwich bread man), much to 「ばいきんまん」 (Germ man)'s chagrin.
アンパンマン (Anpanman) helping people in distress. Often by giving them a piece of his head to eat if they're hungry.
「ばいきんまん」 (Germ man) gave a black heart to 「ロールパンナちゃん」, the older sister of アンパンマン (Anpanman)'s friend 「メロンパンナちゃん」 (Melon-panna chan). If she sees アンパンマン (Anpanman), her heart turns black and she betrays her friends…but when she sees her sister, her heart turns kind again.
After she helps her friends, she always leaves to live in solitude for fear of her heart turning black again.
アンパンマン (Anpanman) is very popular with young children in Japan and his image (as well as many of the other characters) can be seen on all sorts of items from toys to clothes to lunchbox sets to just about anything!
アンパンマンの仲間 (Anpanman & friends)
When my kids were little, they loved アンパンマン (Anpanman).
Last Spring, we visited the 「横浜アンパンマンこどもミュージアム」 ("Yokohama Anpanman Children's Museum").
(Click here to read the post I wrote about it).
Click here to visit the 「アンパンマンとやなせたかし展」 ("Anpanman & Takashi Yanase Exhibit") website (Japanese only).
Click here to visit the official Anpanman website (Japanese only).
and another popular superhero in Japan is Ultraman. I wrote a post about him, too. ( Click here to read it.)
Tags: anime, Anpanman, どきんちゃん, ばいきんまん, やなせたかし, やなせ・たかし, アンパンマン, ジャムおじさん, Baikinman, graduation, Holidays, Japan, Japanese, Japanese character, Japanese holiday, March 20, Mitsukoshi, Spring Equinox, Takashi Yanase, Ultraman, 卒業式, 春分の日, 三越
Categories anime, Celebrities, Events, Holidays, Japan


Love Island Lookbook - Get 15% OFF What The Islanders Wore!
Home Love Island Lookbook – Get 15% OFF What The Islanders Wore!
Love Island obsessives, we've got your back! Here's how you can steal the stars of the show's style, and get a great 15% OFF too.
Everyone's favourite summer TV show is back, and we've managed to get you an EXCLUSIVE code for 15% OFF Missguided! Now you can steal the Islanders' style for less. Use the code ASHLEIGHLOVE to grab some money off.
If you still want to update your summer wardrobe but these pieces aren't really your style, you can still enjoy 15% OFF the rest of the site, including Missguided's beaut holiday shop!
Hayley wore this beautiful baby blue bikini in a recent episode. It would look absolutely perfect paired with a tan! Sunbathing GOALS.
This swimsuit is giving us serious Baywatch vibes, and it's loved by Samira too! She wore it on the show.
How gorgeous is this acid wash pink jacket? Totally perfect for festival season! It was worn by Dani in the show.
Monochrome is always in style, and Rosie sported this bikini in the promo pics for Love Island.
Shop now, get 15% OFF with the code ASHLEIGHLOVE.
M&S Cyber Day – 20% OFF until Midnight Tonight!


Paul Given, the chairman of the Stormont justice committee has got it wrong. The DPP is correct in his decision not to publish the Attorney's report . Liam Adams' conviction is to be appealed and is therefore sub judice.
It exposes Mr Given's lack of understanding [shocking for the chairman of the justice committee] and his poor choice of subject. McGrory is a Director holed below the waterline as a result of his extensive representation of Sinn Fein/PIRA. He is excluded from participation in many prosecutorial decisions because of this.
If Given had any wit he would have made a better fist of this resignation demand by citing more compelling cases , such as the failure to prosecute McGuinness .


Change can be a strange beast.
In one sense, I felt an enormous amount of sadness when I went back to my hometown for the first time in 15 years and saw a town significantly more populated and less clean than the quiet, idyllic place I grew up in.
Then there's the kind of change you can believe in, such as technological advances in medicine or the widespread availability of information to the masses thanks to the Internet's rise. Even video games have gone through a great change in just a decade or so.
"Langrisser: Re:Incarnation Tensei" is not one of those games.
Langrisser Re:Incarnation Tensei features some old-school style graphics.
Like a time capsule that was buried many years ago and unearthed recently, the latest Langrisser is almost unapologetic in its dedication to its old-school formula. Depending on how rosy your rose-colored glasses are, that will either be good or bad. I still remember all the Langrisser ads back in the day when physical video game magazines were still profitable. Most of the real estate of these ads were taken up by Satoshi Urushihara's trademark art with some screenshots thrown in. Given Re:Incarnation's sparse virtual style that harkens back to several generations of consoles, it would actually look at home in those ads.
While featuring solid albeit reused musical score, some voice acting and cutscenes, production values in Re:Incarnation for the actual game are at the low end of the spectrum. Between its overhead and battle sections, the game looks like a mishmash of 8-bit, 16-bit and 32-bit styles. As someone who still remembers playing Atari games, archaic graphics by today's standards are not a deal breaker for me. A good number of people, however, won't be as forgiving and that will be the challenge for Re:Incarnation. It's almost as if the game is trying to be Fire Emblem, except with a fraction of its budget. This is especially apparent in the battle attack scenes, which try to offer 3D models but with minimal detail, animation and movement. Battles involving mob groups admittedly look amusing but the 3D fights are mostly lifeless, especially when battling one one one. It almost would have been better to just present images of two fighters in virtual cards clashing while putting the freed up resources on sprucing up the overhead sections instead.
The actual battle system, meanwhile, while not bad, isn't as layered or in-depth as strategy games like Disgaea or even some of the more iconic strategy titles from older generations. Then again, the system that underpins the combat is definitely an improvement over the game's graphics. In addition to your standard character units, you can hire mercenaries prior to each battle to help you out. These include classes such as militia, abbot and dark elf, each with their own strengths and weaknesses. The more mercenaries you have alive after a battle, the more benefits you get so you'll want to make sure they don't bite the dust if possible. By conversing with allies, you can improve relationships, which adds another layer of strategy to the game. Add secrets that can be discovered during the course of battling and playing and you can top more than 100 hours if you decide to really invest the time into it. Then again, the combat has issues as well, with lack of a quick save during battle being a huge oversight.
Langrisser Re:Incarnation Tensei features new character designs.
The story, meanwhile, is typical gaming fantasy involving multiple factions, which has been told many different ways through the years. You have a powerful empire attacking a town in an apparent attempt to secure a legendary weapon and the hero who ends up wielding it. One plus is that the choices you make along the way can affect the direction of the story, which hangs in the balance between light and darkness. Like the battle system, I don't think the story's horrible either though it certainly isn't as compelling as, say, a Final Fantasy VI, which still managed to tell a good tale despite the limitations of the medium at the time. Then again, FF6 is an almost unfair comparison as that game is, well, a classic.
Like seeing my hometown after a long while, I admit that I also felt some sadness after witnessing Langrisser — but for different reasons. Behind this game is a story and concept that certainly had potential but appears to just not have the resources required for it to be fully realized. My hometown changed too much, I thought. Langrisser: Re:Incarnation Tensei, on the other hand, seems to be stuck in time, or might actually have even regressed given the overall positive history of the Langrisser series.
Langrisser: Re:Incarnation Tensei has the misfortune of being the next strategy RPG that I've played after Fire Emblem Fates, making its flaws seem even more magnified. Behind the low production values is a game with some good ideas. Unfortunately, it looks like its makers didn't quite have the necessary resources — whether it be time, money or both — to fully realize them.
Langrisser: Re:Incarnation Tensei takes the phrase "old school" literally.


text:
Q: Is This VB.net Error A Hosting Environment Error? On a VB.net page, I am clicking an Edit Button on a DataGrid, when I get the below error.  I think this is a hosting environment issue for my hosting company to rectify, rather than an error in my script.  Would you agree?  Do you know what must be done on the server to rectify this type of error?  Thanks.
-- Error Starts --

Could not find a part of the path
  'C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET
  Files\root\244b2b37\c0134493\uploads\inzbg7lz.tmp'.

Description:

An unhandled exception occurred during the execution of the current
  web request. Please review the stack trace for more information about
  the error and where it originated in the code.

Exception Details: System.IO.DirectoryNotFoundException: Could not find a part of the path 'C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET Files\root\244b2b37\c0134493\uploads\inzbg7lz.tmp'.
-- Error Ends --

redpajama_set_name: RedPajamaStackExchange


This is a work of fiction created by a delusional, egotistical moron. Greed was/is his motivating factor if you look at who was really controlling the DOE for all those years. Arne is a decent and nice man, only in his own mind.
Bravo! I cannot imagine a more incisive review. Keep on truckin'!
Fine review of Mr. Duncan's attempted K12 rock-rolling up Sysphus, Mr. Merrow.
First off, only 19 schools made it to the top, begging the question of how's the rarefied view working….not for the schools, but for the students. God bless those Superintendent candidates who come into an urban school district and tell us that we need all students, no matter their skills or talents, above average. Without pausing on the ridiculous here, at least there target is right: the student.
Arne's aim wasn't. Buildings don't get smarter. Students can, though. The simple fact is that if you raise the performance of each student, so will the scores go up for their school. Bingo! But who cares about schools. We need to care about each learner.
Answer: each learner needs their own Personal Learning Plan…created by them and managed by them (with help, of course, from their teachers, parents, mentors). But the students are the ones who have to stand and deliver. They need to show us what they know, and what they are still working on, and what they need to achieve their plan goals. The onus of learning falls first on the learner….not the teacher, not the parent. They are helpers, coaches, encouragers, and hand-clappers. Kids need to do it. They know best and can show they know.
It's the student's needs and performance we need to address….not the schools. Just as Mr. Merrow did with the kid with all that great basketball talent, but lagging in standards skills. When those basketball skills are gone, it sure helps if one can read a good book.
The best thing about NCLB was what the letters stood for, and certainly not for the host of plans that followed. They focused instead on No School Left Behind. What happened to each "Child"? It's even more maddening if we challenge betterment with a race to the top for school districts, states and our nation. It ain't gonna happen, as too many kids would say today.
It's "How Students Work" that matters more. We have nigh of 100,000,000 students in this country who also have the right to life, liberty and the pursuit of happiness. The practice of all those rights is theirs too, and one's own lifelong learning is the key.
So is Public Health, but you generally find health professionals making the choices and policy.
When has there ever been a Surgeon General who did not have some connection to the medical professions? When has there ever been an Attorney General who didn't have a law degree?
Only 3 of the eleven Secretaries of Education had teaching experience in K-12 education.
Education is still something that most people think "anyone can do" since "we all went to school." Unfortunately, the problems facing education are complicated and generally come from the outside such as the effects of poverty on children and their families and the inequity of funding. If Duncan, as a sociologist (his Harvard degree), used his position to try to impact the social order that has led to one of the highest rates of child poverty in the developed world, that would be different. But he didn't. He pushed policies that had a direct impact on how schools were run, how teachers were evaluated, and how tests were used (misused).
Public education is a public responsibility, but, I respectfully disagree, that is not the end of the story. There can be no "race to the top" when kids, schools, and school systems don't all have the same starting point. There can be no "no child left behind" while children are still being left behind economically and socially. We will never be a nation where "every child succeeds" until we are a nation where every child is given a fair chance to succeed.


Earlier this year, Greg and Jenna set up propbooth – a pop up photo booth suitable for all events including weddings, birthdays and family parties.
And choose wisely… will you play it safe or go for the wackiest prop you can find? Picture your Nan wearing a Mardi Gras headdress. Enough said! propbooth has hundreds of props to choose from including moustaches, hats, glasses, masks, accessories, message boards and frames.
2. Always remember: A mous-tache is must-have!
Well, it's not essential – but we think there's nothing better than a moustache prop to create that retro-vintage look.
3. Solo pose or team effort?
This is a tricky one – do you dare to do a solo pose? Actually, many people do, but it's usually in the second half of the event when guests are feeling slightly more relaxed. At the beginning of events its normally groups posing in the propbooth, so why not pluck up the courage and go solo before everyone else… you will have the pick of the props.
You'll end up with the most hilarious pictures with tons of personality, and these are the ones you will treasure forever.
But remember that a little movement is great too – so pop a party popper, blow some bubbles or throw some confetti… doing this creates a little depth in your picture and won't look static.
If you are posing in a group, squish up together and get rid of gaps. You may not get along with that cousin twice removed – but this is a party and you're having fun, so get over it!
Stay put after the first shot so we can take a second, or a third, or a fourth… At propbooth you can have as many pictures as you like – we may capture something brilliant and having a choice of photos is always better.
Got a great picture? Then why not have it turned into a keyring (or fridge magnet). These can be printed instantly at the event giving you a memory to take home and show off to your friends – or to give to someone as a nice little gift.
There's no point having your photo taken if no-one is going to see it! propbooth upload event photos to a private gallery after the event for everyone to have a giggle at. You could even add your favourites to facebook or twitter – you might even find a new profile picture!


The Oriental Spa, at the exquisite Faros Hotel in the heart of Ayia Napa, reflects a particularly beautiful atmosphere that makes every experience unforgettable.
The modern state-of-the-art facilities and unique oriental details, inspired from the East to West, blend in harmony with the holistic spa philosophy, in a luxury refined ambiance.
We invite you to experience the world's leading well-being solutions to beauty & health therapies, a series of specially designed "rituals" encompassing Chinese, Ayurvedic, European, Balinese, Oriental and Indian beliefs and signature practices.
The Spa is complemented by the sumptuous spa facilities, featuring an indoor vitality pool, thermal suite with Finish sauna & steam bath, ice fountain and a state of the art couple's suite with private Jacuzzi.
The gym featuring leading equipment, is offering fitness and rehabilitation programs dedicated to healthy lifestyle.


text:
module StringifyTime
  def stringify_time(*names)
    names.each do |name|
      define_method "#{name}_string" do
        read_attribute(name).to_s(:db) unless read_attribute(name).nil?
      end

      define_method "#{name}_string=" do |time_str|
        begin
          write_attribute("#{name}", Time.zone.parse(time_str))
        rescue ArgumentError
          instance_variable_set("@#{name}_invalid", true)
        end
      end

      define_method "#{name}_invalid?" do
        instance_variable_get("@#{name}_invalid")
      end
    end
  end
end

ActiveRecord::Base.send(:extend, StringifyTime)

redpajama_set_name: RedPajamaGithub


text:
The Hebden and Barden Moor walk in the Yorkshire Dales
From Hebden, south on Mill Lane, across the River Wharfe, and south-east via the Dales Way to Burnsall. Further south and a climb towards Burnsall and Thorpe Fell, before heading to the north-east corner of Upper Barden Reservoir. South-east across Barden Moor to reach Lower Barden Reservoir, and continuing to Barden Tower on the B6160. Back to Burnsall using the Dales Way alongside the River Wharfe, and finally along Burnsall Lane and other footpaths to Hebden. A 13-mile walk in the Yorkshire Dales.
The best map to use on this walk is the Ordnance Survey map of the Yorkshire Dales Southern & Western Area, reference OS Explorer OL2, scale 1:25,000. It clearly displays footpaths, rights of way, open access land and vegetation on the ground, making it ideal for walking, running and hiking. The map can be purchased from Amazon in either a standard, paper version or a weatherproof, laminated version, as shown below.
Standard Ordnance Survey map of the Yorkshire Dales Southern & Western Area, reference OS Explorer OL2, scale 1:25,000.
Weatherproof Active Ordnance Survey map of the Yorkshire Dales Southern & Western Area, reference OS Explorer OL2, scale 1:25,000.
Hebden Suspension Bridge
In 1884, following the drowning of a local man while trying to cross the stepping stones on the River Wharfe below Hebden, a committee was formed with the intention of building a footbridge. A great storm the previous year had also destroyed Burnsall Bridge down stream causing the villagers great problems.
The new bridge was designed as a suspension bridge and was built by the village blacksmith, William Bell. 262 yards of redundant steel rope was bought for it from the Hebden Moor Mining Company. Funding for the bridge was raised through public subscription and a grand opening was held in 1885 with a brass band and a public tea. The bridge now carries a popular public footpath and was recently refurbished by the National Park Authority.
Stepping stones on the River Wharfe, next to Hebden Suspension Bridge.
The River Wharfe.
Burnsall Bridge
The original stone bridge was built in 1609 thanks to a gift of money from local benefactor Sir William Craven who also paid for Burnsall Grammar School. In 1752 it was described as being 'a good bridge and all paved'. It was restored or possibly rebuilt in 1884 following flood damage. It has three main arches and two smaller ones.
The village of Burnsall
A sign near the village bridge says:
Burnsall sits on the bank of the River Wharfe, sheltering beneath Barden Moor, and is perhaps one of the most picturesque villages in the Dales. On the hillsides around it can be seen cultivation terraces or 'lynchets' which were ploughed by some of Burnsall's earliest inhabitants 1000 years ago. Today the river bank is a popular spot for visitors, and others come to the village along the Dales Way path which runs north to the Lake District.
The view of Burnsall Bridge from one of the cairns at the northern tip of Barden Moor.
Upper Barden Reservoir.
Nineteenth century building near Upper Barden Reservoir.
Lower Barden Reservoir.
Barden Tower
A medieval fortified manor house beside the River Wharfe on the eastern fringes of the Yorkshire Dales. The Tower was built in the 15th century by Henry Clifford to replace an earlier hunting lodge.
Barden Bridge
Barden Bridge is an attractive three-arched humpbacked bridge across the River Wharfe north of Bolton Abbey on the eastern edge of the Yorkshire Dales. The bridge crosses the river just north-east of Barden Tower, a 15th-century fortified manor house.
The bridge was erected in 1659 at a cost of £300 and is built of ashlar blocks. There are large triangular cutwaters on the upstream side to minimise the force of the rushing water. The top of the cutwaters creates small pedestrian retreats so that it is relatively safe to walk across the bridge.
On the north side of the east end of the bridge is an inscription reading 'this bridge was repayred at the charge of the whole West riding 1676'.
The date refers to the fact that the original 1659 bridge was swept away in a flood in 1673 and had to be rebuilt. The parapets had to be renewed in 1856 and again in 1956 after flood damage.
The bridge we see today dates from the 17th century but there was certainly a bridge here as early as the 14th century, and probably much earlier than that.
The bridge is very narrow, with an opening of only 10 feet which naturally means that only one vehicle at a time can drive over it.
The bridge is a Scheduled Ancient Monument and is a listed Grade 2 building. An old story – very likely true – says that Barden Bridge was used by William Craven (1548-1618), the son of a local farmer from Appletreewick who went on to become Lord Mayor of London.
Craven's career resembles that of Dick Whittington in that he rose from poverty to become a wealthy merchant and Lord Mayor. It has even been suggested that Craven's life was the inspiration for the legend of Dick Whittington.
If the story is true, it cannot be this bridge that Craven used, for it wasn't built until after his death, but he would certainly have used the earlier medieval bridge that it replaced.
Information sourced from https://www.britainexpress.com/counties/yorkshire/properties/barden-bridge.htm


August 23rd....almost the last hurray of summer 2011!
At least that's the way it seems to me. Tom has been working second shift most if not all of this summer. Usually 6 days a week. Doesn't leave much time to spend together doing fun things. On his only day off, Sunday, we use to go on adventure rides as I call them. Now we spend them catching up on yard work, weather permitting.
We did have a nice 5 day get away this summer, but it seemed to end to quickly for my liking. Wish it could have lasted longer. Maybe it's because I'm retired ~ well, mostly anyway. Sometimes they paper calls me in to fill in for someone who is on vacation or has called in sick or has a sick child. In fact I worked yesterday because the gal I was filling in for had no sitter and knew she wouldn't, so this was set up quite some time ago. A little extra spending money is always nice. But with Tom working 2nd shift and me working days, I only see him if I wait up for him to come home. That's what I'm doing tonight...he should be here around 1:30AM....overtime!
A storm blew in earlier tonight with lots of heavy rain, thunder and lightening. I love thunder storms but am not allowed to enjoy them as in the past. I have these 2 four-legged fur kids who do NOT like thunder and lightening. As a matter of fact they are now smart enough that when it begins to rain they predict thunder and lightening by following me around where ever I go, including into the bathroom! I comfort them as best I can and reassure them that everything will be fine and I am here and won't let anything happen to them. I hope they're around long enough to return the favor to me when I get too old to walk around safely!
Labels: "Four legged fur friends.
............go to a local store and see someone you sure you knew? I did, today! Was positive that it was the mom of my daughters friend, Sherry, who was on the same high school swim team. I said "Hi, how are you?" She smiled back and said "fine, and you?" I told her I was fine also, and asked her how her kids were. She looked at me with a puzzled look on her face and said..."do I know you?" I then asked her if her name was Pat? She gave me a big smile which led me to believe that she had not recognized me at first. She then extended her hand to shake hands with me and said....with a big smile on her face...."My name is Dot and it's always nice to meet new people!"
I should have been embarrassed but I wasn't! I smiled back and mumbled something about when I got really old and had Alzheimer's I would meet new friends every day and started to walk away when she touched my arm and reassured me that it was fine and that she does the same thing sometimes. We laughed, chatted a few more minutes about being moms and grandmas and growing old, and went on our separate ways. Talk about a DUNCE!!!!
I can't believe it is the beginning of August already. 70 Years ago today, my first husband was born. This November 15th will be the 38 Anniversary of his passing! Seems like so long ago now. My children were all little then and now, most of my grandchildren are older than mine were way back then. Had Dave lived, he would have been so proud of his children and grandchildren. How I wonder sometimes, did I ever get through those years of raising them alone.
So many things have happened since then...so many things have changed, and yet some things remain the same! I can't even imagine what things would be like now if he had lived past his 34 years on this earth. Well, that is something that I will never know in this lifetime at least.
Enough of the past.....I always get a little sad on this day wishing he were here to celebrate his birthday with his kids and grand kids.....life goes on!


text:
Q: Proof that $\lim_{x \to \infty} \frac{x^{a}}{b^{x}}=0 $ I have to prove that $$\lim_{x \to \infty} \frac{x^{a}}{b^{x}}
$$
equals zero for all $a$ of $\mathbb{N}$ and $|b|>1$
The suggestion is to start by finding $$\lim_{x \to \infty} \frac{x^{1}}{b^{x}}
$$
which I have done. But what I get is $\frac{x}{b^{x}}$ and since the limit of $b^{x}$ is defined as $0$ I don't know how to continue...

A: Since $\lim_{x\to\infty}x^a=\infty$ and $\lim_{x\to\infty}b^x=\infty$, you can to use L'Hospital's Rule:
\begin{align}
\lim_{x\to\infty}\frac{x^a}{b^x} = \lim_{x\to\infty}\frac{d(x^a)/dx}{d(b^x)/dx} = \lim_{x\to\infty}\frac{ax^{a-1}}{\ln(b) b^x}
\end{align}
Notice, if $a=1$ then the limit in the numerator is just $1$ while the denominator still goes to infinity, so that the limit of the ratio goes to zero. To complete the proof just notice that for any $a \in \mathbb{N}$ you can just repeat the above step $a$ times until you obtain the same result.
Edit: The above proof work for $b>1$. For the case in which $b<-1$ notice that
$$ \frac{d(b^x)}{dx} = (\ln(-b)+\pi i)b^x$$
the limit of which is $-\infty$. So an analogous argument works for that case.

A: If you have done
$$\lim_{x\to \infty} \frac{x}{b^x} = 0, $$
for all $b >1$, then
$$\lim_{x\to \infty} \frac{x^n}{b^x} = \lim_{x\to \infty} \left(\frac{x}{(\sqrt[n]b)^x}\right)^n = \left( \lim_{x\to \infty}\frac{x}{(\sqrt[n]b)^x}\right)^n =0$$
as $\sqrt[n] b$ is still $>1$. Not sure what's going on when $b<-1$.


text:
Trying Out CompStat 2.0, the NYPD's Yelp for Crime
By Samuel Lieberman
Not for the faint of heart.
On Tuesday, the NYPD unveiled a new site where you can sift through and map every crime report in the city: It looks a little like Yelp, but for grand larceny. This is CompStat 2.0, successor to the software that is widely credited with the crime drop of the 1990s, and it is the next iteration of Bill Bratton's flagship data program, which will also include a smartphone for every police officer.
Early in Bratton's first run as police chief, in 1994, he and his late deputy Jack Maple introduced the original CompStat, which isolated and located clusters of low-level crimes and showed cops where to concentrate their efforts. The next year alone saw a 60 percent drop in crime. Although critics have said that officers in the CompStat era have underreported crimes in an effort to game the statistics, nearly everyone agrees that the program has been an enormously effective and relatively nontoxic tool.
CompStat 2.0 takes the data into sortable public view, serving as a weirdly fun way of poking around the city. Murder is down this year by more than 30 percent, robberies by 7 percent, burglaries by 8 percent, and shootings by 25 percent; felony assaults, by contrast, are up 15 percent, perhaps boosted by the anomalous slashing spree of the past month. After 20 minutes' research, charting car thefts by the hour and murders by day of the week, I learned things about my neighborhood: Assaults go way up on the weekends, whereas thieves take it easy.
compstat
new york city police department
Trying Out the NYPD's Yelp for Crime


Mr. Prabhat Ranjan strongly feels that education is not only an instrument to develop the total personality of the child helping him to realize his potential but also a medium to transform the global society into a caring, collaborative and responsible unit of cultured individuals. He believes in education which would array the children in an armor of invincible physical prowess, inquisitive intellect, daring spirit and constructive attitudes. Education which is not acquired but discovered and experienced, which elevates man from materialism to spiritualism.


(April 24, 2018) – Ruoff Home Mortgage has been recognized as one of the top 100 Mortgage Companies in America in 2017, according to Mortgage Executive Magazine. Ruoff ranked #65 with more than $1.597 million in closed volume (10,659 units). Growing to more than 40 locations throughout Indiana, Michigan, Ohio, Kentucky and Florida, their ranking has gone up from #79 in 2016. The full list appears in the Spring 2018 issue.
Mortgage Executive Magazine compiled the most comprehensive list of the nation's top 100 closely-held mortgage companies and publicly-traded banks as ranked by their total yearly mortgage volume for 2017. The publication recognizes and celebrates service, dedication and hard work that mortgage professionals put into building their companies and serving their clients.
Founded in 1984, Ruoff Home Mortgage is a full-service residential mortgage company with more than 40 branches throughout Indiana, Ohio, Michigan, Kentucky and Florida. They have been ranked on the Inc. 500/5000 Fastest Growing Companies in America for the past five years and are also honored as a 2018 Top Mortgage Employer by National Mortgage Professional Magazine. Ruoff Home Mortgage is also licensed to originate in 46 states.


text:
Николай Спиридонович Чирка (15.07.1907, Полтавская область — 19.10.1995, Полтавская область) — сапёр 933-го стрелкового полка 254-й Черкасской Краснознамённой стрелковой дивизии 52-й армии 2-го Украинского фронта, красноармеец. Герой Советского Союза.

Биография
Родился 15 июля 1907 года в селе Борки Зеньковского района Полтавской области. Украинец. Член ВКП(б)/КПСС с 1944 года. Окончил начальную школу. Работал в колхозе.

В октябре 1943 года призван в ряды Красной Армии. С этого же времени на фронте. Воевал на 2-м и 1-м Украинских фронтах. Принимал участие в освобождении городов Черкассы, Умань, Яссы, Бреслау.

В марте 1944 года 933-й стрелковый полк 254-й Черкасской Краснознамённой стрелковой дивизии вёл наступательные бои в районе Ботошаны — Яссы. После прорыва обороны противника 28 марта 1944 года наши воины начали форсирование реки Прут в двадцати километрах севернее города Яссы в Румынии. Командир полка поручил сапёрному подразделению, в составе которого служил Н. С. Чирка, подготовить средства переправы. Эту задачу сапёры успешно выполнили. Под ураганным огнём противника на небольшом плоту Н. С. Чирка всю ночь переправлял бойцов на противоположный берег. Противник методически обстреливал переправу из орудий и миномётов, но не смог остановить наступления советских воинов. Н. С. Чирка на плоту переправил около двух рот солдат, а потом продолжал перевозить боеприпасы.

Указом Президиума Верховного Совета СССР от 13 сентября 1944 года за мужество и героизм, проявленные при форсировании реки Прут и удержании плацдарма на её западном берегу рядовому Чирке Николаю Спиридоновичу присвоено звание Героя Советского Союза с вручением ордена Ленина и медали «Золотая Звезда».

После окончания Великой Отечественной войны демобилизовался. Жил в городе Гадяч. Работал на местном хлебокомбинате. В декабре 1971 года вышел на пенсию. Умер 19 октября 1995 года. Похоронен в городе Гадяч Полтавской области.

Награждён орденами Ленина, Отечественной войны 1-й степени, медалью «За отвагу», другими медалями.

Литература

 За мужество и отвагу. Харьков, 1984.

Ссылки

Сапёры Великой Отечественной войны
Похороненные в Гадяче

redpajama_set_name: RedPajamaWikipedia


text:
Journal of Cardiovascular Pharmacology & Therapeutics Referencing Guide
Citationsy › Style Guides › Journal of Cardiovascular Pharmacology & Therapeutics
How to do citations in Journal of Cardiovascular Pharmacology & Therapeutics style?
This is the Citationsy guide to Journal of Cardiovascular Pharmacology & Therapeutics citations, reference lists, in-text citations, and bibliographies.
The complete, comprehensive guide shows you how easy citing any source can be. Referencing books, youtube videos, websites, articles, journals, podcasts, images, videos, or music in Journal of Cardiovascular Pharmacology & Therapeutics.
How do you cite a book in the Journal of Cardiovascular Pharmacology & Therapeutics referencing style? (2023 Guide)
Are you writing a research paper and want to include the works you found in a book? Here's a simple guide to do it in Journal of Cardiovascular Pharmacology & Therapeutics:
Here's an example book citation in Journal of Cardiovascular Pharmacology & Therapeutics using placeholders:
Journal of Cardiovascular Pharmacology & Therapeutics citation:
And an in-text citation book citation in Journal of Cardiovascular Pharmacology & Therapeutics looks like this: 1
Automate citations and referencing in Journal of Cardiovascular Pharmacology & Therapeutics with our tool, Citationsy.
How to reference a journal article in the Journal of Cardiovascular Pharmacology & Therapeutics citation style?
How do you cite scientific papers in Journal of Cardiovascular Pharmacology & Therapeutics format?
Use the following template to cite a journal article using the Journal of Cardiovascular Pharmacology & Therapeutics citation format.
Here's a Journal of Cardiovascular Pharmacology & Therapeutics journal citation example using placeholders:
So if we want to reference this scientific article: "Testing consumer preferences for iced-coffee: Does the drinking environment have any influence?" by C. Petit and J.M. Sieffermann in Journal of Cardiovascular Pharmacology & Therapeutics:
Automate citations and referencing in Journal of Cardiovascular Pharmacology & Therapeutics with Citationsy. Get started for free
How to cite a website in a paper in Journal of Cardiovascular Pharmacology & Therapeutics style?
The most basic entry for a website consists of the author name(s), webpage title, website title, institution/publisher, publication date, and DOI or URL. Here's how to cite it properly in Journal of Cardiovascular Pharmacology & Therapeutics
Here's an Journal of Cardiovascular Pharmacology & Therapeutics example website reference:
Citing websites and links in Journal of Cardiovascular Pharmacology & Therapeutics is much easier with the Citationsy Chrome Extension →
Cite Journal of Cardiovascular Pharmacology & Therapeutics with Citationsy. Get started for free
How to cite a YouTube video Journal of Cardiovascular Pharmacology & Therapeutics in 2023
You can find short videos and how-to videos from a wide range of professionals on YouTube. As a result, you may need to know how to mention a video or YouTube in your research assignment or paper. Here's how to do it in Journal of Cardiovascular Pharmacology & Therapeutics
Here's a Journal of Cardiovascular Pharmacology & Therapeutics citation YouTube video example:
So how to cite a video Journal of Cardiovascular Pharmacology & Therapeutics?
How to cite a podcast using Journal of Cardiovascular Pharmacology & Therapeutics referencing style
A more entertaining way to learn is to simply listen to a podcast. This is something relatively new that many people still don't know how to cite and reference. Here's how to do it in Journal of Cardiovascular Pharmacology & Therapeutics
Here's how to reference a podcast it in Journal of Cardiovascular Pharmacology & Therapeutics.
Podcast referencing example in Journal of Cardiovascular Pharmacology & Therapeutics using "This American Life" episode 640:
Cite podcasts in Journal of Cardiovascular Pharmacology & Therapeutics with Citationsy, a referencing app used by over 400 000 students.
How to cite a piece of music or a song using Journal of Cardiovascular Pharmacology & Therapeutics referencing style?
Did you know there are well over 100 million different songs you can cite and reference? Here's a simple guide to reference any song in Journal of Cardiovascular Pharmacology & Therapeutics
An example song citation in Journal of Cardiovascular Pharmacology & Therapeutics.
Let's say we want to reference "Here Comes the Sun" off The Beatles "Abbey Road" album in Journal of Cardiovascular Pharmacology & Therapeutics:
You can automate citing and referencing any source in Journal of Cardiovascular Pharmacology & Therapeutics using Citationsy.
Cite sources using the Journal of Cardiovascular Pharmacology & Therapeutics Citation Machine
Cite Journal of Cardiovascular Pharmacology & Therapeutics with Citationsy, a referencing app used by over 400 000 students. Get started for free


text:
Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes
Tod A. Harper, Aditya D. Joshi, Cornelis Elferink
Pharmacology & Toxicology
Proper hepatocyte function is vital for survival;thus, unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver regeneration is clinically important, and evidence that the aryl hydrocarbon receptor (AhR) can promote cell survival after intrinsic apoptotic stimuli is integral to the regenerative process. The current study uses primary hepatocytes to identify survival mechanisms consistent with normal AhR biology. Taking advantage of the Cre-lox system to manipulate AhR status, we designed a comprehensive microarray analysis to identify immediate and direct changes in the transcriptome concomitant with the loss of the AhR. As a result, we identified a unique data set with minimal overlap, compared with previous array studies, culminating in the identification of Stanniocalcin 2 (Stc2) as a novel receptor target gene previously reported to have a cytoprotective role in endoplasmic reticulum stress. The Stc2 promoter contains multiple putative xenobiotic response elements clustered in a 250-bp region that was shown to recruit the AhR by chromatin immunoprecipitation. Of interest, Stc2 gene expression is refractory to classic exogenous AhR agonists, but responds to cellular stress in an AhR-dependent mechanism consistent with a process promoting cell survival.
https://doi.org/10.1124/jpet.112.201111
teleocalcin
Harper, T. A., Joshi, A. D., & Elferink, C. (2013). Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes. Journal of Pharmacology and Experimental Therapeutics, 344(3), 579-588. https://doi.org/10.1124/jpet.112.201111
Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes. / Harper, Tod A.; Joshi, Aditya D.; Elferink, Cornelis.
In: Journal of Pharmacology and Experimental Therapeutics, Vol. 344, No. 3, 03.2013, p. 579-588.
Harper, TA, Joshi, AD & Elferink, C 2013, 'Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes', Journal of Pharmacology and Experimental Therapeutics, vol. 344, no. 3, pp. 579-588. https://doi.org/10.1124/jpet.112.201111
Harper TA, Joshi AD, Elferink C. Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes. Journal of Pharmacology and Experimental Therapeutics. 2013 Mar;344(3):579-588. https://doi.org/10.1124/jpet.112.201111
Harper, Tod A. ; Joshi, Aditya D. ; Elferink, Cornelis. / Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes. In: Journal of Pharmacology and Experimental Therapeutics. 2013 ; Vol. 344, No. 3. pp. 579-588.
@article{e9345024cff94de19765d1d70438c96d,
title = "Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes",
abstract = "Proper hepatocyte function is vital for survival;thus, unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver regeneration is clinically important, and evidence that the aryl hydrocarbon receptor (AhR) can promote cell survival after intrinsic apoptotic stimuli is integral to the regenerative process. The current study uses primary hepatocytes to identify survival mechanisms consistent with normal AhR biology. Taking advantage of the Cre-lox system to manipulate AhR status, we designed a comprehensive microarray analysis to identify immediate and direct changes in the transcriptome concomitant with the loss of the AhR. As a result, we identified a unique data set with minimal overlap, compared with previous array studies, culminating in the identification of Stanniocalcin 2 (Stc2) as a novel receptor target gene previously reported to have a cytoprotective role in endoplasmic reticulum stress. The Stc2 promoter contains multiple putative xenobiotic response elements clustered in a 250-bp region that was shown to recruit the AhR by chromatin immunoprecipitation. Of interest, Stc2 gene expression is refractory to classic exogenous AhR agonists, but responds to cellular stress in an AhR-dependent mechanism consistent with a process promoting cell survival.",
author = "Harper, {Tod A.} and Joshi, {Aditya D.} and Cornelis Elferink",
doi = "10.1124/jpet.112.201111",
journal = "Journal of Pharmacology and Experimental Therapeutics",
T1 - Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target genes
AU - Harper, Tod A.
AU - Joshi, Aditya D.
AU - Elferink, Cornelis
N2 - Proper hepatocyte function is vital for survival;thus, unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver regeneration is clinically important, and evidence that the aryl hydrocarbon receptor (AhR) can promote cell survival after intrinsic apoptotic stimuli is integral to the regenerative process. The current study uses primary hepatocytes to identify survival mechanisms consistent with normal AhR biology. Taking advantage of the Cre-lox system to manipulate AhR status, we designed a comprehensive microarray analysis to identify immediate and direct changes in the transcriptome concomitant with the loss of the AhR. As a result, we identified a unique data set with minimal overlap, compared with previous array studies, culminating in the identification of Stanniocalcin 2 (Stc2) as a novel receptor target gene previously reported to have a cytoprotective role in endoplasmic reticulum stress. The Stc2 promoter contains multiple putative xenobiotic response elements clustered in a 250-bp region that was shown to recruit the AhR by chromatin immunoprecipitation. Of interest, Stc2 gene expression is refractory to classic exogenous AhR agonists, but responds to cellular stress in an AhR-dependent mechanism consistent with a process promoting cell survival.
AB - Proper hepatocyte function is vital for survival;thus, unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver regeneration is clinically important, and evidence that the aryl hydrocarbon receptor (AhR) can promote cell survival after intrinsic apoptotic stimuli is integral to the regenerative process. The current study uses primary hepatocytes to identify survival mechanisms consistent with normal AhR biology. Taking advantage of the Cre-lox system to manipulate AhR status, we designed a comprehensive microarray analysis to identify immediate and direct changes in the transcriptome concomitant with the loss of the AhR. As a result, we identified a unique data set with minimal overlap, compared with previous array studies, culminating in the identification of Stanniocalcin 2 (Stc2) as a novel receptor target gene previously reported to have a cytoprotective role in endoplasmic reticulum stress. The Stc2 promoter contains multiple putative xenobiotic response elements clustered in a 250-bp region that was shown to recruit the AhR by chromatin immunoprecipitation. Of interest, Stc2 gene expression is refractory to classic exogenous AhR agonists, but responds to cellular stress in an AhR-dependent mechanism consistent with a process promoting cell survival.
U2 - 10.1124/jpet.112.201111
DO - 10.1124/jpet.112.201111
JO - Journal of Pharmacology and Experimental Therapeutics
JF - Journal of Pharmacology and Experimental Therapeutics
10.1124/jpet.112.201111


text:
Anticlinura movilla is a species of sea snail, a marine gastropod mollusk in the family Mangeliidae.

Description
The length of the shell attains 4.9 mm, its diameter 2.6 mm.

(Original description) The small, thin, white shell has a fusiform shape. It contains about five whorls beside the (eroded) protoconch. The suture is distinct and slightly appressed. The anal fasciole is narrow, nearly smooth except for lines of growth, bordered in front by an inconspicuous angular shoulder. From this shoulder extend (on the body whorl about eighteen) feeble, narrow, subequal, protractive, axial riblets, with subequal interspaces, crossed by fine, close-set spiral threads. The ribs extend to the suture, or on the body whorl to the base, and the threads cover the whole surface. The anal sulcus is shallow. The outer lip is thin, simple, moderately arcuate. The columella and the body are smooth, the former obliquely attenuated in front, not pervious. The siphonal canal is short, wide and slightly recurved

Distribution
This marine species occurs in the Pacific Ocean off Acapulco, Mexico.

References

  Tucker, J.K. 2004 Catalog of recent and fossil turrids (Mollusca: Gastropoda). Zootaxa 682:1-1295.

movilla
Gastropods described in 1908


text:
HomeHotelsAscend Hotel Collection debuts 300th hotel on Martha's Vineyard Island
Ascend Hotel Collection debuts 300th hotel on Martha's Vineyard Island
November 7, 2019 TTD
The Ascend Hotel Collection reaches a significant milestone with the opening of its 300th hotel worldwide on the renowned Massachusetts island of Martha's Vineyard, Edgar Hotel – Martha's Vineyard.
The Ascend Hotel Collection has reached a significant milestone with the opening of its 300th hotel worldwide on the renowned Massachusetts island of Martha's Vineyard, Edgar Hotel – Martha's Vineyard.
This year alone, the upscale brand has welcomed nearly 60 properties to its portfolio of resort, historic and boutique hotels in destinations including Brooklyn, New York; Melbourne, Australia; New Orleans; Portland, Maine; and San Francisco.
Built in a classic Cape Cod style, the newly renovated Edgar Hotel – Martha's Vineyard is located at 227 Upper Main Street, just a few blocks from the quaint New England town of Edgartown, which is rich in maritime history and full of boutique shops, restaurants, fishing piers and picturesque harbor views.
The 41-room hotel is also a short drive to Katama Beach on the Atlantic Ocean and other Martha's Vineyard towns, including Oak Bluffs and Vineyard Haven, as well as popular attractions like the nation's oldest merry-go-round, the gingerbread cottages at Oak Bluffs Campground, "Jaws Bridge" where the iconic Jaws movie was filmed, and scenic bike trails.
"Ascend is known for providing guests with a one-of-a-kind upscale lodging experience to help satisfy their travel curiosity in new destinations," said Janis Cannon, senior vice president, upscale brands, Choice Hotels.
"It's fitting that we achieved this milestone in Martha's Vineyard, which perfectly reflects the brand's resort, boutique, and historic nature.
"We look forward to strengthening our foothold as the industry's largest soft brand and bringing even more hotels to our guests' seeking cultural immersion and local experiences in their favorite locations around the world."
Guests of the Edgar Hotel – Martha's Vineyard can enjoy amenities such as outdoor space with a large patio and fireplace to take in the scenery and enjoy the fresh, crisp ocean air.
Visitors and locals alike can dine at Town Bar and Grill on the hotel's grounds, which features local fare, craft beer and cocktails, nautically inspired décor with guestrooms that include cathedral ceilings, oversized windows and white-washed wood bedframes.
Other amenities are standard rooms or suites, including free Wi-Fi and smart technology with streaming capabilities, a business centre, free onsite parking and guest laundry facilities.
"Hotel owners love the Ascend brand as much as guests because of the flexibility it offers by marrying operational independence with Choice's industry-leading technology, robust distribution channels and award-winning loyalty programme," said Mark Shalala, vice president, franchise development, upscale brands, Choice Hotels.
"In fact, the brand is creating so much demand that, in the third quarter this year alone, Ascend grew its room count by nearly 10 per cent and its global development pipeline is now over 100 hotels strong,"
UNWTO: Tourism leaders discuss tourism's role in rural development
IHG increases its visibility in Vietnam with two hotels on the Ho Tram Strip


text:
Owen Williamson USA
American Electoral Dialectics: A Comment on the 2022 US ''Mid-Term Elections''
Owen Williamson USA//2:23am, Nov 10th '22
The November 8, 2022 American elections have come and gone, with most reported results showing divided control over Congress, State and local elected offices. If anything is remarkable about the elections it is the reported closeness of results, with reports of literally dozens of important races around the country being decided by one or two percentage points between contenting candidates.
Widespread pre-election media warnings of possible political violence (E.g., "Right-wing support for political violence 'is no longer a fringe position,'" or "What happens if Election Day gets Disrupted?") appear to have been stirred up as a deliberate tactic to keep elderly, fearful or uncommitted voters from voting. In response, even the Communist Party USA's People's World website felt it necessary to publish a pre-Election Day guide entitled, "If you're threatened or hassled on Election Day, here's what to do." In the American electoral system, absolutely dominated by the two major parties (Republican and Democratic), it has long been axiomatic that "elections are decided by turnout" (i.e., the number of voters who bother to come out to vote for a given candidate or party) and not simply by popular support or voiced enthusiasm for one candidate or the other. In the 2022 elections, in spite of false rumors of coming violence, turnout was still better than average for an "off-year" election, but lower than when a presidency is at stake. And no election-related violence was reported anywhere in the United States.
Particularly among observers on the international Left, there has often been a tendency toward a summary, ultra-leftist dismissal of American elections as "all for show," correctly noting that the two major American political parties are twin pillars of the capitalist system. In spite of tendencies like that suggested in an October, 2022 poll, that a "Majority of Democrats Favor U.S. Moving Toward Socialism and Away From Capitalism," such policy differences as do exist between the two parties are still dismissed as cosmetic only.
And, in a dialectical sense, a deeply cynical analysis of the phony nature of the American two-party system has much to recommend it, especially as it is seen from outside the USA. The reality is that American foreign policy is never seriously debated in U.S. elections, including in 2022. At least since the beginning of World War II, both major parties have silently agreed on the proposition that "politics stop at the water's edge," i.e., that American Imperialism must never be questioned or even seriously challenged in domestic politics. Perhaps the only exception to this rule was popular opposition to the war against Viet Nam in the 1960's and 1970's, an opposition which was finally victorious at home thanks to a decade of hard and occasionally heroic ongoing mass protests by young Americans. However, even in that case, neither major party ever dared to voice solid opposition to the war until the very last, when the Vietnamese victory on the battlefield was already in sight.
And even today, generations later, the principle, that "politics stops at the water's edge," is still largely axiomatic in American capitalist politics. Thus, whether the serving American president be Bush or Obama, Trump or Biden, US aid and weapons will still flow to South Korea and to Taiwan, to Israel and to Saudi Arabia, and fierce U.S. hostility to all those who oppose American domination, whether from the left (e.g., Cuba) or from the right (e.g., Iran) remains undiminished.
However, at this point it is useful to remember the principle of solidarity, that American working people, while certainly materially benefitting to some degree from U.S. Imperialism, are also at the same time oppressed by it, and that oppression can widely vary in nature and degree depending on which American party and which politician is in power. Particularly if one does not live under this reality every day it is tempting to wave one's hand and shout, "More oppression? Less oppression? There's not a coin's worth of difference! If a 'moderate' American leader is going to keep up the very same material support to Israel or Taiwan as a proto-fascist might, or arrest or drive out asylum-seekers at the US border exactly like a "right-winger" did, what's the difference?"
Unfortunately, if American workers are facing the risk of neo-Fascism this necessarily affects working people in the rest of the world as well. One way this can work is suggested in a troubling pre-election article published by "AlterNet," entitled "Legal expert maps out Republicans' plan to hold the 'entire global economy hostage' if they win the midterms." As the world saw in the worst possible way during the 20th Century, ultra-right politics does not normally confine itself to one country. In fact, for a Fascist, war and aggression are regarded as good and natural, "manly" and even "healthy" and "cleansing." This is the type of ideology American voters are facing, and even though the alternatives (Biden and the Democrats) are just as Capitalist, it is hard to deny that Biden is far less likely to launch an unprovoked foreign military or economic adventure than the American hard-right would if allowed unfettered access to the levers of power.
Sourav Chakraborty India//1:06pm, Nov 4th '20
Ongoing protest against anti-abortion law in Poland is a war between the working class women and Christian fundamentalist
The outrage of protest in Poland is now well known to all. On 22nd October, a court ruling of Poland imposed ban on all cases of abortion except for a pregnancy that threatens the mother's health or....
Yanis Iqbal India//11:38pm, Apr 27th '21
Syria's Ignominious Role in the Lebanese Civil War
April 9, 1976. The Syrian military intervenes in Lebanon to fight against the National Movement (NM) and Palestinians. Kamal Jumblatt - the leader of the NM - was too radical for the liking of Damascus.....
Akash Chatterjee India//1:38am, Mar 4th '21
Catalonia: Pablo Hasel And The Resurgence of the Left
The pictures of mass gathering and agitations are nothing new on the streets of Catalonia. Since 2017, the streets of Catalonia have been witnessing huge mass upsurges and movements against the authoritarian....
Nathan Russell UK//3:14am, Jul 20th '22
Tolpuddle Martyr Festival and Young Communist League, Britain : Review of the 2022 Festival
The Tolpuddle Martyr's Festival in the South West of England's equivalent to Durham Miner's Gala in the North East. It also commemorates the battle Dorset agricultural workers waged against the British....
Luis Lazaro Tijerina USA//11:02pm, Dec 23rd '21
CHAPTER II: WITHIN THE WALLS: A memoir of the plague in Quebec City
Continuation of the second chapterIt was during my excursions to the Morrin Center, located not far from where I lived on Mont Carmel, that I found some peace of mind, and I could read in peace, and meet....
Chris Richards USA //8:02pm, Dec 22nd '21
Tall poppy Theory: Who Are The Bourgeois?
According to Livy, the Roman King Tarquinius Superbus sent his son Sextus to the rival city of Gabii to undermine it politically. Sextus pretended to have rebelled against his father and "fled" to....


text:
Tag Archive for: tourette s syndrome
The Only Two Traits You Need for Success as an Entrepreneur
August 21, 2012 /in Business Development/by George Krueger & Mary-Lynn Foster
We've been doing some research about the history of the term "entrepreneur." And we uncovered an interesting fact.
At least we think so; we hope you do too!
Origins of entrepreneur
According to the Online Etymology Dictionary, "entrepreneur" originates in the French language. It is the "agent noun" for "entreprendre", which means undertake.
So entrepreneurs are undertakers? We weren't sure we liked that.
So we did some more research. Thanks to The Word Detective, we learned that "undertaker" was used more generally until late in the 17th century (e.g. contractors).
At that time, funeral directors began using the term to describe their occupation. It turned out that was the death (we couldn't resist!) of the word for everyone else.
However, to this day, the primary definition of "undertaker" – according to Merriam-Webster – is "one that undertakes: one that takes the risk and management of business: entrepreneur".
Kind of interesting, eh? But we didn't really know what to say about it until we saw this…
The second trait
We recently listened to a conversation between Bob Burg and Josh Hinds – two of our favorite people. They chatted about Josh's fantastic book, It's Your Life – Live Big. (Yes, we've teased Josh about spelling "BIGG" wrong!)
In the title to his post, Bob called Josh an "overcomer." It's one great way to describe Josh. He has Tourette's syndrome. But he didn't let that slow him down. Not only is he an author, he is an entrepreneur and speaker!
One word – overcomer. Suddenly the scales fell off the eyes. The world was clear again.
BIGG success comes second
You can be an entrepreneur with just the first trait. You can be an undertaker.
But BIGG success as an entrepreneur comes from the second one – you have to be an overcomer.
However, you won't have anything to overcome if you never undertake!
It's the two together that pack the punch.
Undertake. Overcome. It's all you need to do to be a BIGG success!
What have you overcome? How did you do it?
Image in this post from stock.xchng
https://biggsuccess.com/wp-content/uploads/2020/07/bigg-success_stacked-1080.png 1080 1080 George Krueger & Mary-Lynn Foster https://biggsuccess.com/wp-content/uploads/2015/07/BIGG-Success-Nurturing-Your-Inner-Entreprener.jpg George Krueger & Mary-Lynn Foster2012-08-21 07:00:042012-08-20 14:35:50The Only Two Traits You Need for Success as an Entrepreneur
How to Live Big – Part 1
May 8, 2012 /in Personal Development/by George Krueger & Mary-Lynn Foster
We're happy to welcome Josh Hinds back to The BIGG Success Show. Besides being one of the best people you could ever hope to meet, Josh is one of the pioneers of personal development online. He's here today to talk about his new book – It's Your Life, Live BIG.
The book will be released in June, but Josh gave us a sneak peak and we LOVE it. But we wanted you to hear about it straight from the man himself.
Josh's book opens with a very frank revelation. He has Tourette's. And of all things he could have chosen to do, he decided to be a public speaker! Not a combination most people would think of. Learn about Josh's journey and how he overcame is fears.
Click a player to hear Josh talk with George & Mary-Lynn on The BIGG Success Show Podcast! (Duration 8:35)
http://traffic.libsyn.com/biggsuccess/00807-050812.mp3
iPhone/iPad/Mobile/Podcast Player
[haiku url="http://traffic.libsyn.com/biggsuccess/00807-050812.mp3″ title="The BIGG Success Show #807″]
We also talk about:
Why his original idea was to simply be a conduit to share personal and professional resources as a hobby.
What he thought his only option was because of his Tourette's syndrome.
How the opportunities that came his way shaped his philosophy of "It's Your Life, Live BIG".
The revelations Josh learned at an early age working in the family business and how helped him become a pioneer of personal development online.
You can get a sneak peak of Josh's book now for FREE here.
Next time find out why Josh says ability isn't the reason many people don't feel successful, and find out what is!
Direct link to The Bigg Success Show audio file | podcast:
https://biggsuccess.com/wp-content/uploads/2020/07/bigg-success_stacked-1080.png 1080 1080 George Krueger & Mary-Lynn Foster https://biggsuccess.com/wp-content/uploads/2015/07/BIGG-Success-Nurturing-Your-Inner-Entreprener.jpg George Krueger & Mary-Lynn Foster2012-05-08 06:00:562012-05-07 22:30:37How to Live Big – Part 1


text:
Apatura iris
Fri 15th October 2010 16:49 by Graham Smith
Agaricus lanipes at Stow Maries Airfield
Thursday October 7th 2010 : During a fungi foray at the First World War Airfield at Stow Maries (TQ8199) around 15-20 specimens of this species were found on either side of the bridleway hedge that flanks the eastern boundary of the old airfield. They were growing in clusters both beneath the hedge and in the field opposite, recently planted with new woodland by the owner of the airfield. This species keys out to Section Spissicaules in Flora Agaricina Neerlandica (2001), two principal characteristics of which are yellowing rhizomorphs at the base of the stem and brown girdles beneath the ring. Both features can be clearly seen on the photographs below although the former broke off when the mushrooms were removed from the caespitose clump they were part of, leaving only a stump. The scales on the cap become broad and flattened (lanate) with age while the flesh, like many brown capped Agaricus, turns pink when cut but pale yellowish white, later brown, in the base of the stem. Both cap and stem turn yellowish on handling, the latter often fading to brown, as is evident here. The spores were 6-7um in length; elliptical and without a germ pore. Most of the specimens were close to the point of no return and even the younger examples illustrated here were often riddled with insect holes.
There are no records on the BMS Database for this species in Essex but in his article on Agaricus in the EN No.23 (2005/2006) Tony Boniface lists a single record from Belhus Woods Country Park, made by Mary Smith. Thus this would appear to be the second County record.


Answer: In Rose-Hill, Mauritius. Chilhood and adolescent years with parents, relatives and friends. The warm Indian Ocean in the lagoons and wonderful mountains in particular Le Corps de Garde which watched over all my childhood games.
Answer: Flying kites and playing boule kass kot, boule siffon and la mok delivrey bare foot in Solferino street with children of various ethnic backgrounds.
Answer: My parents did not. I was an orphan when I came with my family in January 1973.
Answer: The freedom to live and achieve without the many barriers found elsewhere.
Answer: Teaching English to children of migrant backgrounds.
Answer: Serving with the British Army in the Middle East. Teaching young kids in primary schools in Mauritius. Being awarded a British Council scholarship to study in Scotland. Working at the Audio Visual Center, (now known as the College of the Air) as a teacher of French on TV and a teacher of English by radio. President of The Cerne Club in Mauritius. Board member of the Racing Club, Mauritius since its foundation until my coming to Australia.. Secretary of the Club National de l'Etrier, a horse riding club in Mauritius. Member of le groupe liturgique at Notre Dame de Lourdes,Rose-Hill. Broadcasting live commentaries on Les Messes des Malades sur les ondes du Mauritius Broadcasting Corporation(MBC). Moving to Australia. Head of the Migrant English Section; and Information Officer at the Commonwealth Department of Education. Starting the first French-language radio programs in Melbourne on Access Radio 2ZZ and Ethnic Radio 3EA. Sitting on the board of the Alliance Francaise for the past 20 years. Mauritian Community Representative on the Catholic Council for Immigration for the Archdiocese of Melbourne for five years. Starting a Mauritian Program in Kreol, French, English on Community Radio 3SER. Becoming a member of the Catholic organization: Knights of the Southern Cross. Becoming a Minister of the Word for the Church as well as a Funeral Minister. President of the Victoria Mauritian Association, Central Region in 1977. Member of the board of directors of Community Radio 3SER. Founder member of Waverley Gardens Probus Club. Ex-Member of various Mauritian Club Committees such as MSA.
Answer:Two of them. A la Recherche du Temps Perdu by Marcel Proust and Souvenirs d'Enfance by Marcel Pagnol.
Their sense of humour and fair play.
A judgmental-moralistic approach to life. Self-righteousness. Inferiority and superiority complexes.
Those who achieve but remember their humble beginnings.
Curried jackfruit and tripes.With lentilles noires and boiled rice.
Putting my children through university. To having successfully sat,after turning 34 ,for the HSC,BA and Diploma in Education while being a family man. Bringing my family to Australia without a sponsor.
Visit to the basilica of Notre Dame de la Garde(Bonne Mere) in the company of Marcel Pagnol, Fernandel,Marius et Olive and my wife, Gisele.
Being with my family especially my grand children.
Acquire more skills. Better acquired ones. Achieve and achieve more while enjoying life!
Most cherished is the small size of the island which allows access to extreme points in a short time, and its diversity.
The Victory celebrations of World War II.
My wife, 3 Children and myself emigrated to Melbourne in early 1966.
The casual relationship between people, which acts as an equaliser, socially as well as in business.
Export Operations Analist at Ford Motor Co. of Australia.
They were many, but essentially being appointed to the Asia Pacific Region as a Field Manager, with extensive travel to a large number of Countries. And later as Sales Manager to Government Fleets in Australia, + Export Sales Manager.
Any good book on History and Scientific matters.
Egocentrics, selfishness. Avoiders of realities.
Easy – Pope John Paul II who single-handedly demolished the Russian Empire, and opened widely the church hierarchy to global prelates.
Ène bon Vindye, homemade !!
Think & talk straight. (I think !).
My unbroken career of 34 years at Ford Australia (32 as an executive), after being sacked as the Ford Sales Manager (Dealership) in 1965 in Mauritius.
Receiving my appointment at Ford Australia, three days after my arrival here.
A Round-the World travel to places I have not visited. Would need to be an extended tour. I am hungry to see and learn more.
At 70 ? The quality of life in my family's environment.
Keep a strong interest, from the side-lines, into the maturing of the Mauritian community through its many organisations and associations in Melbourne, in Australia at large.


text:
Q: React TypeScript: Correct type for dynamic path The router looks somthing like this
import { BrowserRouter, Route, Switch } from 'react-router-dom';

...
<Route exact path='/confirm-email/:confirmationCode' component={ConfirmEmail} />
                                        ^
//                                      This is the value that gets passed to the props

And the component that gets loaded is
import { RouteComponentProps } from 'react-router-dom';

interface PropsInterface extends RouteComponentProps<{}> {
  confirmationCode: string;
}
const ConfirmEmail: React.FC<PropsInterface>  = (props: PropsInterface) => {
  const confirmationCode = props.match.params.confirmationCode;
                                                   ^
//                                                 Error Here!

The error I get is Property 'confirmationCode' does not exist on type '{}'.ts(2339)

This is not a duplicate of react-router-dom with TypeScript as it does not address the dynamic path being passed as a prop

A: :confirmationCode is part of the Route props, props.match.params.confirmationCode
So a prop that belongs to RouteComponentProps
Therefore you need to pass it to RouteComponentProps like:
import { RouteComponentProps } from 'react-router-dom';
interface PropsInterface extends RouteComponentProps<{confirmationCode: string}> {
 others:any; // Other props that belong to component it self not Router
}

or more clear if you want to destruct more Route params
   interface IParams { confirmationCode:string; ....  }
   interface IProps extends RouteComponentProps<IParams>{....}

SO you see this is exactly the same as what is covered in the duplicated question? the differences are namings.


text:
=head1 LICENSE

 Copyright (c) 1999-2011 The European Bioinformatics Institute and
 Genome Research Limited.  All rights reserved.

 This software is distributed under a modified Apache license.
 For license details, please see

   http://www.ensembl.org/info/about/code_licence.html

=head1 CONTACT

 Please email comments or questions to the public Ensembl
 developers list at <dev@ensembl.org>.

 Questions may also be sent to the Ensembl help desk at
 <helpdesk@ensembl.org>.

=cut

package Bio::EnsEMBL::Variation::Pipeline::BaseVariationProcess;

use strict;
use warnings;

use Bio::EnsEMBL::Variation::Pipeline::TranscriptFileAdaptor;

use base qw(Bio::EnsEMBL::Hive::Process);

sub param {
    my $self        = shift;
    my $param_name  = shift;

    my $param_value = $self->SUPER::param($param_name, @_)
        or die "$param_name is a required parameter";

    return $param_value;
}

sub get_transcript_file_adaptor {
    my $self = shift;

    unless ($self->{tfa}) {
        $self->{tfa} = Bio::EnsEMBL::Variation::Pipeline::TranscriptFileAdaptor->new(
            fasta_file => $self->param('proteins_fasta'),
        );
    }

    return $self->{tfa};
}

sub get_species_adaptor {
    my ($self, $group) = @_;

    my $species = $self->param('species')
        or die "species is a required parameter";

    return $self->get_adaptor($species, $group);
}

sub get_adaptor {
    my ($self, $species, $group) = @_;

    my $dba = Bio::EnsEMBL::Registry->get_DBAdaptor($species, $group);

    unless (defined $dba) {
        $self->_load_registry();
        $dba = Bio::EnsEMBL::Registry->get_DBAdaptor($species, $group);
    }

    unless (defined $dba) {
        die "Failed to a get DBA for $species and group $group";
    }

    return $dba;
}

sub _load_registry {
    my ($self) = @_;

    my $reg_file = $self->param('ensembl_registry')
        or die "ensembl_registry is a required parameter";

    Bio::EnsEMBL::Registry->load_all($reg_file, 0, 1);

    return;
}

1;


text:
define([
  'underscore',
  'backbone',
  'models/menuItem'
], function( _ , Backbone , MenuItemModel ){

	var MenuCollection = Backbone.Collection.extend({

    model: MenuItemModel,

    initialize : function(models, options) {

      this.on( "change:selected", this.changeSelected );
    },

    changeSelected: function( model, val, opts ){

      if( val ){
        this.each( function( e ){
          if( e != model && e.get( "selected" ) ) {
            e.set( "selected", false );
          }
        });
      }
    }
  });

  return MenuCollection;
});


As wild felids are obligate carnivores, it is likely that poorly enzymatically digestible animal tissues determine hindgut fermentation, instead of plant fibre. Therefore, faecal concentrations of short-chain fatty acids (SCFA, including branched-chain fatty acids, BCFA), indole and phenol were evaluated in 14 captive cheetahs, fed two different diets differing in proportion of poorly enzymatically digestible animal tissue. Using a cross-over design, the cheetahs were fed exclusively whole rabbit or supplemented beef for 1 month each. Feeding whole rabbit decreased faecal propionic (p < 0.001) and butyric (p = 0.013) acid concentrations, yet total SCFA was unaltered (p = 0.146). Also, a remarkably higher acetic acid to propionic acid ratio (p = 0.013) was present when fed whole rabbit. Total BCFA (p = 0.011) and putrefactive indole (p = 0.004) and phenol (p = 0.002) were lower when fed whole rabbit. Additionally, serum indoxyl sulphate, a toxic metabolite of indole, was analysed and showed a quadratic decrease (p = 0.050) when fed whole rabbit. The divergent SCFA ratios and the decrease in putrefaction when fed whole rabbit could be caused by the presence of undigested tissue, such as skin, bone and cartilage, that might have fibre-like functions. The concept of animal fibre is an unexplored area of interest relevant to gastrointestinal health of captive cheetahs and likely other felids.
Depauw, Sarah, Myriam Hesta, Katherine Whitehouse-Tedd, Lynn Vanhaecke, Adronie Verbrugghe, and Geert Janssens. 2013. "Animal Fibre: The Forgotten Nutrient in Strict Carnivores?: First Insights in the Cheetah." Journal of Animal Physiology and Animal Nutrition 97 (1): 146–154.
Depauw, Sarah, Hesta, M., Whitehouse-Tedd, K., Vanhaecke, L., Verbrugghe, A., & Janssens, G. (2013). Animal fibre: the forgotten nutrient in strict carnivores?: first insights in the cheetah. JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 97(1), 146–154.
Depauw S, Hesta M, Whitehouse-Tedd K, Vanhaecke L, Verbrugghe A, Janssens G. Animal fibre: the forgotten nutrient in strict carnivores?: first insights in the cheetah. JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION. 2013;97(1):146–54.
Depauw, Sarah, Myriam Hesta, Katherine Whitehouse-Tedd, et al. "Animal Fibre: The Forgotten Nutrient in Strict Carnivores?: First Insights in the Cheetah." JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION 97.1 (2013): 146–154. Print.


Alina Suchanski's recently published book Alone – an Inspiring Story of Survival and Determination tells the story of a young Polish orphan who came to Pahiatua in 1944. Based on the life of her stepfather Tony Laparowski, it recounts his early childhood in Poland, his family's deportation to the Soviet Union at the start of World War II where both his parents had perished, and his journey as an orphan from Kazakhstan, Uzbekistan and Persia to New Zealand. Although Alina's stepfather read the completed manuscript, sadly he hasn't seen his story in print. He passed away in May 2012 before Alone was published.
Ms Suchanski who spoke no English when she came to New Zealand as a refugee herself in 1982, said that writing this book took her eight years and was the biggest challenge of her life. Based on her stepfather's memoirs hand written in Polish, she spent several years researching the book which included interviewing remaining family members in Poland and employing an historian to gather further information. Alone is her second book, publishing Polish Kiwis – Pictures from an Exhibition in 2006.
The talk will also include the screening of an excerpt from the documentary Poles Apart. Produced by Ms Suchanski in 2004 it presents the story of the Pahiatua Children, interviews with the representatives of this group and their personal memories.
The opportunity to hear Alina talk about her book Alone will appeal to anyone with an interest in Polish history and the Pahiatua orphans, the journey of refugees to New Zealand, or simply about the human capacity to overcome adversity.