By Indre Viskontas & Kishore Hari. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio streamed directly from their servers.
We talk to Matt Richtel about his new book An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives.
301 episodes available. A new episode about every 5 days averaging 31 mins duration .
Indre wrote a book! It's called How Music Can Make You Better and this week we hear all about it.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
A careful look into research on whether or not we can generate new neurons as adults; new research into using machine learning to predict premature death; and a new technique to reshape cartilage by heating it.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to Jeremy Lent about his book The Patterning Instinct: A Cultural History of Humanity's Search for Meaning.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to Christie Aschwanden about her new book Good To Go: What the athlete in all of us can learn from the strange science of recovery.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to Matt Richtel about his new book An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
A study taking a deep look into insect populations and their decline; bad news about global warming four generations from now, new research showing why older mice benefit from receiving younger blood; and a new study on microwaving grapes.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to Jennifer Ouellette, science writer and former director of The Science & Entertainment Exchange, about last year's best and the worst science movies and tv.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to Blake J. Harris about his new book The History of the Future: Oculus, Facebook, and the Revolution That Swept Virtual Reality.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
The science behind the polar vortex, a new study attempting to directly translate brain signals into speech, and an update on the incredible work of neuroscientist Ed Boyden.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to New York Times best-selling science writer Maria Konnikova about her book The Confidence Game: Why We Fall for It . . . Every Time.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to psychologist Ellen Winner about her new book How Art Works: A Psychological Exploration.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to bestselling author Daniel Pink about his latest book When: The Scientific Secrets of Perfect Timing.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to David Amodia, a social neuroscientist and psychology professor at NYU and the University of Amsterdam, about the science of prejudice.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: Kishore looks back through 2018 and lays out his favorite science stories of the year.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to Dave Williams, a Canadian astronaut, neuroscientist, physician, and author of the new book Defying Limits: Lessons from the Edge of the Universe.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to author Robert Greene, most known for the bestselling The 48 Laws of Power, about his new book The Laws of Human Nature.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
Carl Zimmer is a New York Times columnist and author of 13 books about science. We talked to him about his latest book, She Has Her Mother's Laugh: The Powers, Perversions, and Potential of Heredity, which was recently named The Guardian's Best Science Book of 2018.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: A study that tracked ants using little backpacks and a look at a new study suggesting a connection between differences in the DNA of our neurons and Alzheimer's.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We follow up last week's dino-episode by talking to paleontologist at University of Edinburgh Steve Brusatte about his new book The Rise and Fall of the Dinosaurs: A New History of a Lost World.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to science writer David Quammen about his new book The Tangled Tree: A Radical New History of Life.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
Up To Date: 10/19/2018By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to paleontologist, professor, expeditioner, and science communicator Ken Lacovara about his book Why Dinosaurs Matter. Ken has unearthed some of the largest dinosaurs ever to walk our planet, including the super-massive Dreadnoughtus, which at 65 tons weighs more than seven T. rex.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: Stingrays are especially affected by oil spills because they're so good at smelling; and research into using a spicy cactus to treat pain.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to evolutionary biologist and managing editor at New Scientist Rowan Hooper about his new book Superhuman: Life at the Extremes of Our Capacity.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: A look into what the midterm election results mean for science; moths developed a 'stealth shield' to hide from bats; and the kilogram is retiring.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to journalist, geologist, and author Betsy Mason about her latest book, co-authored with Greg Miller, All Over the Map: A Cartographic Odyssey.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week Kishore catches up with previous guests Nick Caruso and Dani Rabaiotti to talk about their new book True or Poo?: The Definitive Field Guide to Filthy Animal Facts and Falsehoods.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to science writer at Wired magazine Matt Simon about his new book Plight of the Living Dead: What Real-Life Zombies Reveal About Our World—and Ourselves.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: A new study attempts to extend the life of worms and what it might mean for us; and a detailed look into the recent failed Soyuz rocket launch.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to Arnold Van de Laar, a surgeon in the Slotervaart Hospital in Amsterdam, about his new book Under the Knife: A History of Surgery in 28 Remarkable Operations.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: We recap the 2018 Nobel Prizes and look at a study exploring a new way to use electrical stimulation to regenerate nerves.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to mathematician and science writer Hannah Fry about her latest book Hello World: Being Human in the Age of Algorithms.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to artificial intelligence expert and former president of Google China Kai-Fu Lee about his recent book AI Superpowers: China, Silicon Valley, and the New World Order.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk with cognitive psychologist Steven Pinker about his recent book Enlightenment Now: The Case for Reason, Science, Humanism, and Progress.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to writer and historian Dan Flores about his book Coyote America: A Natural and Supernatural History.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: Kishore takes a closer look at some of the health claims made during the recent Apple Keynote.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to celebrated science journalist Richard Harris about the "reproducibility crisis" in science and his new book Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to political scientist Eric Oliver about the surprisingly high percentage of people who believe in conspiracy theories and the reasons behind those beliefs. His forthcoming book is Enchanted America: How Intuition and Reason Divide Our Politics.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
This week: A new study shows we only focus on something a few milliseconds at a time, but we don't notice because we're pulsing that focus; and research on how ants avoid traffic jams so perfectly. Thanks to guest co-host Trace Dominguez!By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to author Andrea J. Buchanan about her experience with a brain injury and how she used playing the piano to recover. Buchanan's new book is The Beginning of Everything: The Year I Lost My Mind and Found Myself.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
We talk to chemist Joseph Meany about his book Graphene: The Superstrong, Superthin, and Superversatile Material That Will Revolutionize the World.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
Ben Goldfarb is a writer covering wildlife conservation and fisheries management. We talk to him about his new book Eager: The Surprising, Secret Life of Beavers and Why They Matter.By adam@adamisaak.com (Indre Viskontas & Kishore Hari).
Start listening to Inquiring Minds on your phone right now with Player FM's free mobile app, the best podcasting experience on both iPhone and Android. Your subcriptions will sync with your account on this website too. Podcast smart and easy with the app that refuses to compromise.


ANN: kbmMW Professional and Enterprise Edition v. 5.04.10 released!
We are happy to announce v5.04.10 of our popular middleware for Delphi and C++Builder.
– Fixed bugs and improved XML<>ON conversion.
– Fixed bugs in TkbmMWConfiguration.
– Added OnAccessException event to TkbmMWCustomFileClient.
Checksum(Ex) and LocalChecksum use SHA256 to calculate checksum.
SameFile(Ex) calculates checksum on both local and remote file and compares those.
On platforms supporting TkbmMWScheduler, the calculations are run in parallel.
piggybacking additional data to events.
– Added WhenException methods to TkbmMWScheduledEvent to allow handling exceptions.
multiple parallel jobs that will be run under control of one scheduled event.
Only when all jobs has run, the scheduled event is considered to have run.
should prefer defining XML node values as attributes or as elements.
should include index (i) attribute to precisely identify a row in an array.
– Updated many database adapters to prevent certain leaks on exceptions.
that is allowed to be received by the server. Default no limit.
– Added TkbmMWVirtualConfigurationStorage to kbmMWConfiguration unit.
It allows for getting and storing configuration from any type of medias.
– Added TkbmMWMarshal.Bytes2Memory function in kbmMWGlobal.
– Added ToString to IkbmMWAutoValue.
strings with start and end tags as delimiters.
– Added PrettyChar2String function to IkbmMWLogFormatter.
– Made Char2PrettyChar function in IkbmMWLogFormatter implementers public.
– Added TkbmMWThreadONObject and TkbmMWThreadONArray to kbmMWObjectNotation.
They allows for multithreaded access to the same base object notation object or array.
– Added additional support for CoInitialize and CoUnInitialize for UNIDac adapter.
– Added BasicProperties property to IkbmMWAMQPChannel.
– Updated database adapter wizard to generate up to date code.
– Improved stability of TkbmMWFileService, TkbmMWFileClient and TkbmMWFilePool.
– Improved error handling in kbmMWORM.
– Fixed bugs in TkbmMWScheduler.
– Fixed compilation errors in AMQP on some IDE SKU versions.
– Fixed header properties not available under some circumstances in AMQP.
– Fixed bugs in TkbmMWAuthorizationManager.
– Fixed bugs in kbmMWConfiguration.
– Fixed bugs in kbmMWHTTPUtils resulting in stack overflow.
– Fixed some null handling issues in TkbmMWObjectNotation.
– Removed leftover debug code from TkbmMWBPStringMaskPart.
– Fixed bugs in TkbmMWAMQPChannel.
– Fixed NULL marshalling issue in TkbmMWONNullableMarshal.
– Fixed kbmMWServer not instantiating minimum number of services at startup.
– Fixed IDE Debug visualizers.
– Improved GetStreamEx and PutStreamEx to allow for retry on failure in TkbmMWCustomFileClient.
– Generally improved exception and error handling in TkbmMWCustomFileClient.
– Improved PutStreamEx to include offset and total file size in server call.


text:
Die Zwölf Königreiche (jap. , wörtlich: "Die Aufzeichnungen der Zwölf Länder") ist eine nicht abgeschlossene Light-Novel-Reihe (illustrierte Romane) von Fuyumi Ono () mit Illustrationen von Akihiro Yamada. Sie umfasst sechs Romane und eine Kurzgeschichtensammlung, die zwischen 1991 und 2001 von Kōdansha veröffentlicht wurden. Studio Pierrot setzte die Reihe als Anime mit 45 Folgen um, der in Japan zwischen dem 9. April 2002 und dem 30. August 2003 auf NHK ausgestrahlt wurde. Darüber hinaus diente die Serie als Vorlage für zwei PlayStation-2-Spiele, die 2003 bzw. 2004 von Konami veröffentlicht wurden, für ein mittlerweile eingestelltes Online-Rollenspiel sowie für einige Hörspiele.

Handlung

Die Oberschülerin Yōko ist ein sehr unsicheres Mädchen, das versucht mit jedem so gut es geht auszukommen. In letzter Zeit wird sie vermehrt von Albträumen geplagt, die ihr keine Ruhe lassen. Eines Tages taucht ein seltsam gekleideter Mann namens Keiki im Klassenzimmer auf, nennt Yōko "die Eine" und bittet sie mit ihm an einen sichereren Ort zu kommen, da sie verfolgt würde. Er drängt Yōko zur Eile, kniet vor ihr nieder, bietet ihr seinen Schutz und seine Seele an und bittet sie zu akzeptieren. Völlig überrascht akzeptiert Yōko. Kurz darauf taucht ein vogelähnliches Monster auf, vor dem sie auf das Schuldach flüchten. Dort treffen sie Yuka und Asano, zwei Schulkameraden Yōkos. Als es zum Kampf mit dem "Vogel" kommt, gibt Keiki Yōko ein besonderes Schwert und "beseelt" sie mit einer Art "Geist", wodurch es Yōko gelingt das Monster zu besiegen. Schließlich nimmt Keiki Yōko und ihre Kameraden, von welchen sie sich nicht trennen will, durch eine Art Dimensionsstrudel mit in seine und, wie er behauptet, auch Yōkos Welt. Dort werden sie kurz nach der Ankunft von Keiki getrennt und es beginnt eine komplexe Geschichte im Land der "12 Königreiche".

Romane und Kurzgeschichten
Vorläufer von Die Zwölf Königreiche war der Horrorroman Mashō no Ko (, wörtlich: Dämonisches Kind), der am 25. September 1991 bei Shinchōsha erschien. Dieser handelt von einem Jungen (Taiki), der aus einer anderen Welt in das moderne Japan kommt. Einige Ereignisse aus diesem Roman wurden auch in die folgende Romanreihe übernommen.

Jūni Kokuki besteht aus sechs Romanen und einer Kurzgeschichtensammlung. Die Erstveröffentlichung fand vom 20. Juni 1992 bis 5. September 2001 beim Imprint Kōdansha X Bunkoban statt und bestand aus 11 Romanbänden, da einzelne Romane in zwei Teilen veröffentlicht wurden. Diese waren illustriert von Akihiro Yamada. Vom 15. Januar 2000 bis 15. Juli 2001 erfolgte eine Zweitveröffentlichung ohne Illustrationen beim Imprint Kōdansha Bunkoban in 9 Bänden. Seit dem 1. Juli 2012 erscheint eine Neuveröffentlichung bei Shinchōsha, beginnend mit Mashō no Ko und dem zweiteiligen ersten Roman.

Die Reihe ist jedoch wie der Anime offiziell noch nicht abgeschlossen. In Japan verkauften sich die Romane (Stand: 2007) mehr als acht Millionen Mal.

Von August 2007 bis April 2010 wurden die ersten vier Romane unter dem Namen Die Zwölf Königreiche bei Tokyopop veröffentlicht. Übersetzer sind Heike Boudalfa und Kimiko Nakayama-Ziegler.

 Der Schatten des Mondes. Das Meer der Schatten (, Tsuki no Kage. Kage no Umi): Yōko wird Kaiserin des Landes Kei.
 Das Meer des Windes. Am Rande des Labyrinths (, Kaze no Umi. Meikyū no Kishi): Taiki wählt den Kaiser des Landes Tai.
 Der Östliche Meeresgott. Das Blaue Meer im Westen (, Higashi no Watatsumi. Nishi no Sōkai): Spielt chronologisch vor den anderen Romanen. Shōryū, der Kaiser des Landes En, unterdrückt eine Rebellion.
 Tausend Meilen des Windes. Himmel im Morgengrauen (, Kaze no Banri. Reimei no Sora): Yōko, Suzu and Shōkei befreien die Provinz Wa in Kei.
 Tonan no Tsubasa (): Shushō wird Kaiserin des Landes Kyō.
 Tasogare no Kishi. Akatsuki no Sora (, wörtlich: Küste in der Abenddämmerung. Himmel in der Morgendämmerung): Risai trifft Yōko um Hilfe bei der Beschwörung von Taiki zu erbitten.
 Kasho no Yume (, wörtlich: Kashos Traum): Verschiedene Kurzgeschichten die in den Ländern Tai, Hō, Kei, Sai und Sō spielen.
 Toei ()
 Jōgetsu ()
 Shokan ()
 Kasho ()
 Kizan ()
 Hisho no Tori ()
 Rakushō no Goku ()

Anime
Der Anime basiert auf der mehrbändigen Romanreihe. Da diese jedoch sehr lang und komplex ist, werden im Anime mehrere Handlungsstränge angefangen, die aber mit der Einstellung der Serie bei Folge 45 zwar angeschnitten, aber nicht alle aufgelöst werden. Die Handlung konzentriert sich auf Yōkos Geschichte.

Der Anime verfilmte folgende Romane und Kurzgeschichten:
 Folgen 1–14: Tsuki no Kage, Kage no Umi (dt. Mondschatten, Schattenmeer)
 Folgen 15–21: Kaze no Umi, Meikyū no Kishi (dt. Meer des Windes, Ufer des Labyrinths)
 Folge 22: Shokan
 Folgen 23–39: Kaze no Banri, Reimei no Sora (dt. Wind aus der Ferne, Himmel im Morgengrauen)
 Folge 40: Jōgetsu
 Folgen 41–45: Higashi no Watatsumi, Nishi no Sōkai  (dt. Gott der Meere des Ostens, Ozean des Westens)

In Deutschland wurde der Anime von Anime Virtual unsynchronisiert mit deutschen Untertiteln auf fünf Doppel-DVDs als 12 Kingdoms – Juuni Kokki veröffentlicht.

Synchronisation

Einzelnachweise

Weblinks
  (japanisch)
 Offizielle Website von NHK zum Anime (japanisch)

Light-Novel-Zyklus
Literatur (20. Jahrhundert)
Literatur (21. Jahrhundert)
Kurzgeschichte
Fantasyliteratur
Anime-Fernsehserie
Zeichentrickserie
Hörspielserie (Japanisch)
Fernsehserie der 2000er Jahre

redpajama_set_name: RedPajamaWikipedia


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Refreshing fruity sweet, sour and lemon-like flavor and aroma of lemon grass oil. The aroma of the oil is similar to the fresh and crisp scent of Lemon.
Of Interest: The name cubeba is given to this plant because the small round fruits resemble those on the climbing shrub piper cubeba, a native plant of Java. You may also see Litsea cubeba under the names May Chang or mountain pepper.
Traditional Use: The oil is mostly used in the fragrance industry. The root and stem of the plant are used in Chinese medicine.
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text:
West Brom to sign off pre-season preparations with Spanish inquisition
The Baggies will take have a sunshine friendly the week before the season starts
West Bromwich Albion manager Tony Pulis
West Bromwich Albion will round off preparations for the new Premier League season with a friendly against Mallorca.
The Baggies will take on the Spanish Segunda Division side at the Iberostar Stadium, Palma, in an 8pm kick off (British time) on Saturday, August 6.
Why future of West Brom ace could rest on AC Milan and Sunderland
The match, seven days before Albion launch their league campaign at Crystal Palace, will be the Baggies' eighth and final friendly.
Albion lost 2-1 to Paris Saint Germain during their training camp in Austria last week before beating National League North side Kidderminster Harriers by the same score line on Saturday.
A West Brom 11, including James Morrison as captain, saw off Stafford Rangers last Saturday with Rickie Lambert among the goals in a 2-1 win.
Tony Pulis and his players fly out to Holland on Wednesday ahead of the FOX Sports Cup.
The four-team tournament will see West Brom take on hosts Vitesse Arnhem on Thursday and Dutch champions PSV Eindhoven on Saturday.
Why the prospect of a West Brom takeover is daunting
Albion also have a double header in Devon with League Two Plymouth Argyle the opposition on Saturday, July 30, before the Baggies visit non-league Torquay United two days later.
Mallorca ply their trade in Spain's second tier having been relegated from La Liga in 2012/13, ending a run of 16 successive seasons in the country's top flight.
The club, who won the Copa del Rey in 2003, competed in the UEFA Champions League in 2001/02 after finishing third in La Liga the previous season.
Albion plan to announce ticket information for the Mallorca clash in the next few days.

redpajama_set_name: RedPajamaCommonCrawl


text:
Brisa Maracujá
Beers, Waters & Soft Drinks
Created in Madeira in 1970, this was the first soft drink in the world to be made from pure passion fruit juice (Passiflora Edulis) with added sugar and carbonated water and without any added colouring agents. Extremely refreshing as it is when consumed on its own, it can nevertheless also be combined with gin or vodka.
This year, the Monde Selection jury members awarded this beverage the Grand Gold Award for the thirteenth time.
This product comes bottled in a glass bottle with a holding capacity of 0.36 cl. Before serving, the beverage needs to be stirred in order to disperse the pulp that accumulates at the bottom of the bottle.
The very natural fragrance of passion fruit becomes immediately apparent on the nose thanks to its intensity, the product containing no less than 9% of the juice in question.
In the mouth, it is still the very natural quality of the product that expresses itself. It is very well supported by a significant sweetness but also very well balanced out by the natural acidity of the passion fruit, thus conferring a very thirst-quenching dimension to the beverage as a whole.
This flavour, as sweet as it is refreshing, lingers in the mouth for a long period of time after tasting.
For all these characteristics, in addition to the Grand Gold Quality Award mentioned above, the Monde Selection tasters have also decided to nominate this product among those likely to win the 2022 Jury Prize in its category.
"Each year, one product per category is awarded the Prize of the Jury as a token of excellence in know-how and quality. In order to qualify, the product must be unanimously selected as a "coup de cœur" by the jury members. The winner of the Prize of the Jury is then selected from a group of just 5 nominees, which makes this award an even greater honour for the recipient."
Schlappeseppel Edel-Doppelbock
The very complex nose expresses beautiful roasted notes of malt combined with nuances of smoke, but is also complemented by certain fruity touches tending towards apricot and dates...
Yakima Valley de San Miguel
The Yakima Valley is an IPA type beer created in Spain by the San Miguel brewery. It owes its name to the Yakima valley from which its hops derived.
From this company
Brisa Maçã sem açúcar View Detail
Brisa Maracujà sem açúcar View Detail
Atlântida View Detail
Coral Branca View Detail
For the tastings of Beers, Waters & Soft Drinks, Monde Selection relies on the expertise of eminent experts such as technicians, master brewers, chemical engineers, who grant the Bronze, Silver, Gold or Grand Gold awards at the end of the evaluation process.


Brake, the road safety charity, alongside Licence Bureau released a report at the end of May which found that many employers with vehicle fleets are not making the best use of new technologies to protect vulnerable road users. There is help out there to support HGV fleet owners to have better vision and see pedestrians and cyclists but employers simply aren't taking advantage of it.
The research found that only one in five HGV operators who took part in the survey had rear-facing cameras on all of their vehicles and only one in twelve had side-facing cameras on all vehicles, with the same amount having side sensors too.
With this new research in hand Brake has appealed to employers to follow the best practice available to them and implement the latest safety technology to suit their vehicles, so as to protect other road users and themselves. By implementing the best technologies employers will also reap the benefits of reduced crashes, bumps and scrapes to their fleet and therefore lower insurance premiums.
The report also found, on the positive side, that the technologies designed for HGVs which have been made mandatory by European law were present on almost all vehicles. These included things such as underrun protection and wide-angle lenses. As these are mandatory Brake wants to see other technologies such as the side-view cameras and side sensors made mandatory too as it seems to be the way of ensuring employers are doing everything they can to protect other road users. Simply describing it as best practice unfortunately doesn't seem to be enough.
The report also found that safety management technologies like telematics are becoming more popular, there is scope for fleet managers and companies with fleets of vehicles to do more to make the most of them. Half of the employers surveyed are not yet using telematics at all and many of those who do are not making full use of their systems, by their own admission.
At least 24% of all road deaths and serious injuries involve a vehicle which is being driven for work, there is a clear need for employers to make a move towards improving the safety of their vehicles. HGVs are involved in 23% of cyclist deaths and 13% of pedestrian deaths and this is whilst they only make up 5% of the vehicle population of the UK. In 2013, 78 people riding a bike or walking were killed by a HGV.
HGVs are always going to be one of the riskier vehicles on the road so those in charge of their safety measures in place should take a step forward in ensuring best practice.


Home » Blog » Do All Chaga Mushrooms Look The Same?
Anytime you are harvesting mushrooms it is important to be able to accurately identify the mushroom. A case of mistaken identity when it comes to mushrooms could be costly for your health. Fortunately, there are several key ways to identify Chaga mushrooms if you want to harvest them yourself.
Chaga has the appearance of a charred conk. It protrudes from the bark of the tree. The conk is very hard. When opened, the conk presents a more orange/brown color, with a slightly spongy texture. The conk will be difficult to remove from the tree and usually requires force from additional tools, such as a small axe. Most Chaga is similar, particularly in color, but not all Chaga looks exactly the same. Some Chaga is large and more pointed, while other Chaga is smaller and more rounded. Shapes and location on the tree can vary quite a bit. The color is what remains consistent for all Chaga mushrooms.
Finding Chaga can be confusing because tree burls and other infections can look very similar to Chaga. You can tell a burl from Chaga because a burl will look closer to the color of the tree bark. A burl is a deformation of the tree itself, so it will look more like the tree. A Chaga mushroom will have a dark, burnt look that is very distinct from the tree. Other infections typically won't have the unique orange color that is found on the inside of the conk. The color combination of charred outside and orange/brown inside can be a sure indicator of Chaga.
Keep in mind that Chaga only grows in northern climates that support birch forests. So the northeast United States, Canada, Northern Europe, Russia, and parts of Asia are the only places that facilitate the growth of Chaga. Outside of this climate, you will not be able to track down this special mushroom. Chaga is also easy to identify because it only grows on birch trees. If you encounter a charred looking conk on a tree other than birch, it is not Chaga, and will not have the same beneficial properties.
When you find Chaga, remember that it must be harvested very carefully to avoid damaging the tree. Chaga that is removed effectively can grow back and be harvested again in about three years. ChagaHQ suggests leaving at least 15% of the Chaga behind so that you don't risk cutting or damaging the tree and the Chaga remains healthy. Don't harvest Chaga from a dead tree, it will not have the same beneficial properties. It is also believed that Chaga is most beneficial when harvested during the winter. Chaga that is located close to urban areas may be contaminated with pollutants. Make sure you are searching for your Chaga in remote parts of the woods.
If you have any questions about harvesting the right mushroom or don't have access to the right environment to find Chaga, you can trust that Chaga Natural's products are harvested sustainably and from some of the most remote parts of Siberia. While finding your own mushrooms is thrilling, don't let lack of time, knowledge, or location keep you from experiencing the healthy benefits of Chaga.


Statistics have shown that their are approximately 142 marijuana users, 62 people abusing prescription drugs, 23 cocaine addicts, 10 people using hallucinogens, and 5 people that use inhalants who live in Cottonwood, California.
There will also be close to 18 people arrested for drug charges and around 13 DUIs in Cottonwood this year.
If you realize that you will need aid with a chemical addiction problem you have made the first and hardest step toward recovery, however the next step of seeking that help may be a daunting task if you don't know where to look. This page provides a list of public, private, non-profit, gay, and Christian drug rehabilitation programs and addiction specialists near Cottonwood, California.
Cottonwood is located in Shasta County and contains the following zip codes: 96022.


Haha, okay okay, I give. Seems like there's more than a few of you that want to keep the site up after the story is over, so here's the link for donations to hosting costs. $86 will keep the site going for another year so that's the goal.
I want to stress again that I'm not asking for anyone to donate. Also, just in case, it wouldn't hurt to tuck Shades of Gray's other location away in your bookmarks. I can't save all the wonderful comments made on this site, but at least you'll always have access to the story there.
Anyway, there's one last page of the story proper to go, then we're in the epilogue. Home stretch, everyone!
My heart strings ache with every sentence and I love every minute of it. This is why I like this comic so much.
Also, lets go around one more year.
Ok, BIG shout-out: "thanks, Avsaroke!!" You rock!!
I'd love it if the site was here for another year, so I can reread it. Several sites have had issues where backups were not tested for viability, and whole comic archives were lost. So, just one more year, please. I'll cough up some cash.
Well, that's $10 donated toward the next year's hosting bill.
I'm okay with people using replies to this message to say how much they've donated. That way we'll know how close we are to the $86 goal.
Thanks you guys. We're currently sitting at $66.27 to go.
If worst comes to worst I will be able to pay off all of it at the end of the month. We have 60 days right?
"Accounts overdue for 60 days will be suspended for non-payment.
So not great, but it sounds like there's some wiggle room.
Donated $10. Loved this comic for ages and would love people to still be able to discover if for at least a little while longer.
Yeah my biggest worry is people who jumped off the comic 2017 and earlier or when the initial announcement was made that things would stop being drawn all the time coming back and having no idea how to find the ending.
I'm just going to assume this is up to date.
Oh yeah. . . that was ambiguous. $27 donated.
And that's the next year's hosting paid for.
On behalf of myself and all other people who are enjoying this site, thank you to everyone who contributed (I'm presuming Avsaroke will say thank you but simply hasn't had time yet).
Now we can enjoy the story on this site for another year, which will hopefully also give more people an opportunity to bookmark the link to the alternate site.
How about taking a full backup of the entire site including subdomains, and re-hosting it somewhere cheaper? There's quite a lot you can do. You know about subdomains; I was thinking moving to kahmith.yourportfolio.com, saving the domain costs. And you probably know that domains themselves only cost like $5/year, so the rest is hosting, and you can get that for a lot less than $81/year, if maybe of less reliability and services and all that. But for an archived site you don't need much. And if you do have another portfolio site you can perhaps piggyback on the hosting with or without its own domain, depending on the hoster. I have a handful of project-specific domain names all pointing to (eventually) subdirectories of my one hosting plan, so the only thing I pay extra for is the domain registration. Drop the hosting costs to a quarter and the same donations last four times as long. Obvious, but worth pointing out at this point in time.
I b'lieve that Avsaroke is wanting her life back. She's quite capable of speaking for herself, but told me (and others) that that somewhere along the line, she ran out of energy for the comic. Not that she doesn't love it still, but she wants more of her life back than the comic was willing to give her. She had a fight with it and the comic lost. And Avsaroke was gracious, kind enough, and generous enough to switch to text mode to finish the story for us. Not that she doesn't love her story, or love her readers, just that she needs her IRL back.
How much work do you suppose it is to pack up an entire site and park it somewhere the maintenance costs are lots lower than current? Given that you only need to do that once, that it should keep all the comments, and you can even pass the package to someone else to do the re-hosting bit for you.
So I think that your protective stance is cool and all, but it misses the point: This is exactly the thing to do to wrap-up the whole thing once the story is done so as to keep it around for those interested AND keep the headache of maintenance down. And again, this only requires someone with access and some dealing-with-hosting clue.
Oh, wow, YNH. That sounds so easy the way you mention it. Are you *volunteering* to do all that work? You should totally reach out privately to Avsaroke if that is the case.
If not, please understand it's a PITA for most people (and I say that as someone who does it professionally). It's been mentioned several times this past year Avsaroke needs to let the comic go.
It's a gift she's been been finishing the story for us in writing to give us readers/fans a conclusion. There are many artists (including print published ones—don't get me started or I will rant about Saga's "hiatus") who don't always do even that much.
All that said, it seems like this is all a moot point. A donation link is open, and I'm sure this will be funded as there are a lot of us who are happy to contribute.
This was never meant to be a happy ending story.
Nooo! Now I'll never know why he hated basking!
Sure you will. I'm going to be answering every last question people have about the story, characters, etc over on my Tumblr once we're all wrapped up here.
1) What's up with Tatith and his hating to bask?
2) What was up with Jael in general?
I'm just getting the story finished off before I take on that project because I'm anticipating some looong answers.
Because you are, quite simply, the Best, EVAR!!
I have a few questions to add to the list.
1. What was the significance of Ixion (the word and the side-comic)?
2. What is up with the creatures attacking kilm? Why are they called "the lost" and how did the gods learn of it?
YAY! It is a gift in a gift in a gift. 😀 I appreciate all the layers being revealed to the stories.
Interesting that no one in Ten's circle has died yet.
I guess it pays to be chums with a god…or it at least prolongs your life a *little* longer. Not sure if that's going to be a good thing in this case given it's got to be a bit hellish to survive a potential apocalypse.
Ohhh that's what that was. I got really excited because I thought it was just a random donation as just a general thank you.
There's a specific link for direct hosting costs in the author's comments, but I'll toss that $20 over to it for you.
So yeah, that'll bring it down to $6.27.
So if our co-conspirator, Venalitor, coughed up the last of the $$ for the site on the site, then keep my $$ as a bonus, to make you smile. Dunno what you like for poison? Since I don't drink anymore, I sometimes wake up by the side of a road in the ditch.
Then I find a 'Dove Extra-Dark' square in my pocket, and know that I'm Not gonna make it to work, today, or maybe not tomorrow, either.
Money's a bit tight right now so an extra $20 is a very welcome gift.


text:
José Antonio Oteo
Email: jaoteo@riojasalud.es
Phone: +34 941 278 770 (Ext.: 89871)
José Antonio Oteo (MD, PhD in Medicine and Surgery, University of Navarra, 1990) is a Specialist in Internal Medicine (MIR Program carried out at Hospital Virgen del Camino, Pamplona, Spain). He has been the Head of the Internal Medicine Service of the Hospital of La Rioja and Hospital San Millán-San Pedro- in La Rioja. He is currently the Head of the Infectious Diseases Department (formerly known as Clinical Management Area) at the Hospital San Pedro, La Rioja (Spain). He is also the Head of the Infectious Diseases Department of the Center for Biomedical Research of La Rioja (CIBIR), which includes three units: the Laboratory of Special Pathogens (Center of Rickettsiosis and Arthropod-Borne Diseases); the Unit of Infectious Diseases, Microbiota and Metabolism and the Unit of Infections, Inflammation and Aging. In this research center, he manages and supervises a laboratory equipped with the latest technologies in molecular and cellular biology and a biosafety level-3 facility for handling dangerous and fastidious microorganisms.
In the field of arthropod vectors research, the group that he leads has been pioneer in the description of new tick-borne diseases, such as DEBONEL, and/or non-previously described illnesses in our environment. They have also significantly contributed to the isolation and involvement of new microorganisms in human pathology, such as Rickettsia monacensis or the new Rickettsia rioja. Besides, other Rickettsia spp., such as Rickettsia vini or Rickettsia colombianensi (to date no associated with human diseases), have been characterized. The biggest series of patients with Lyme disease in Spain and studies in the arthropod vectors have been also reported by this group. The first cases of human anaplasmosis in the South of Europe, the first cases of Rickettsia sibirica mongolitimonae infection, the first implication of Rickettsia massiliae as human pathogen in America, the first case of neurotoxic paralysis after tick-bite, the circulation of Ca. Neoehrlichia mikurensis in Spain, and the description of tularemia after tick-bite are among other relevant achievements. The first cluster of cases of human Rickettsia felis infection in Spain and the first infestation with trombiculid mites (Neotrombicula inopinata) as causative agents of seasonal dermatitis in the world have been also described by this group. It is also worth mentioning the first description of Crimean-Congo hemorrhagic fever in ticks from Occidental Europe and in ticks removed from migratory birds in the North of Africa. These findings were essential for a rapid health response to the first two autochthonous cases detected in Spain in August-September 2016. In addition, this group has managed more than 1 million euros in research funding in recent years.
Concerning his activity in the Unit of Infectious Diseases, Microbiota and Metabolism he has focused his interest on the study of gut microbiota composition in different infectious and relevant pathologies through next-generation technologies. He has also been involved in the analyses of data obtained by transcriptomics and lipidomics in order to find out early biomarkers of these pathologies. In addition, he has also participated in several national and international projects in this field and has published several studies in high impact journals.
His experience in lecturing includes the post-graduate training of resident doctors, his involvement in several PhD courses carried out in different Universities as well as his contributions as Invited Professor in several courses in the field of Medicine and Nursing. He is the Professor in charge of the practices of medical students in the Hospital San Pedro and the person in charge of lecturing Physiology-I in the Degree of Nursing of the University of La Rioja. He has supervised several Doctoral Theses, Diploma of Advanced Studies (DEAs), Master Projects and Final-Degree Projects. He is accredited by the ANECA as Profesor Titular de Universidad in the area of Medicine.
As result of his research activity, he has published more than 350 publications in scientific journals, books and monographs. During his professional practice he has participated, as principal investigator (PI) in most cases, in numerous competitive research projects.
He currently leads a clinical group associated with the Spanish Infectious Pathology Research Network (REIPI); his team is also part of the Spanish AIDS Research Network (RIS); he is an expert of the VectorNet network, which depends on the ECDCs, and is member of the European Network for Neglected Vectors and Vector-Borne Infections (EurNegVec Cost Action). Recently, his team has joined the Network of Biological Alert Laboratories (RE-LAB), set up to respond to threats by dangerous biological agents. His contributions frequently appear in official programs of national and international congresses of relevance in the field of infectious diseases. He has been the Chairman of the Scientific Committee of the Congress of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and President of several National and International Study Groups, such as the Special Pathogens group of the SEIMC and the Coxiella, Anaplasma, Rickettsia and Bartonella group from the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). He is part of the editorial committee of several scientific journals and acts as evaluator of the National Agency for Evaluation and Prospecting (ANEP) and of different agencies from other countries such as Portugal, Norway and Argentina. He has also the honor of having received numerous scientific and social awards.
Arthropod Vectors, Infectious Diseases, Microbiota and Metalobism, Inflammation and Ageing Unit


Matt is ready for another profitable NHL season and he is already off to a great start! He is coming off a winning card which continued the recent hot streak and he is now 41-21 YTD while going a SCORCHING 203-127 (+$47,296) since the start of last season! Do not miss out on his Game of the Week and CASH in on a MASSIVE Winner! Guaranteed!


ST. LOUIS, MO., JULY 15, 2013 – RF Controls LLC, a leading provider of advanced radio frequency identification (RFID) smart antenna hardware and software, today announced that it has consolidated operations at their new headquarters located at 1400 South 3rd Street, Suite 220, St. Louis, MO 63104.
RF Controls LLC chose the Kirburg Building for its location, ease of access for clients and technological advancements that provide an environment conducive to our growing product mix. "Consolidating our staff under one roof will enable us to operate in a more collaborative environment enabling greater communication between departments thus enhancing productivity and, most important, product performance and quality," said Graham Bloy, Chief Scientist and co-founder. "We are delighted with the new environment and the impact it has already had on our staff and day to day operations of the company," Bloy continued.
RF Controls, LLC, a leading provider of advanced radio frequency identification (RFID) technology, was founded in 2006 by businessman and entrepreneur, Tom Ellinwood, and Chief scientist and technology developer, Graham Bloy. The company's patented Intelligent Tracking and Control System (ITCS®) provides real-time location system (RTLS) functionality, using only passive, ultra-high frequency (UHF) radio frequency identification (RFID) tags to identify, locate and track items. The system is now in use at some of the world's largest and most influential companies. For more information about RF Controls, contact Todd A. Spence, Senior Vice President of Investor Relations, at 314-720-0895.


When spores land on wet surfaces in a crawlspace, attic, basement, shaded or secluded areas of your property, mold can easily and quickly take hold and begin an insane rate of growth. Controlling indoor moisture and humidity is a step in the right direction. However, in order to completely eliminate your mold issues, any water problems must be resolved.
Both intense flooding and slow leaks can proliferate the bacteria that causes mold. However, these situations are very different, the inspection and remediation process is the same.
The methods and procedures we employ are compliant with current Occupational Safety and Health Administration (OSHA) standards, as well as Environmental Protection Agency (EPA) Regulations.
Requiring 3rd party post mold remediation testing ensures that the work and process performed by the Remediation Contractors was indeed effective and has left the structure safe for dwelling or occupancy. 3rd party post testing should be administered by a qualified and certified Indoor Air Quality Professional, contracted independently from the remediation contractor.
All of our technicians have met the requirements and are certified by the IICRC, being the industry's top certification level. We guarantee that our mold remediation process is thorough and that upon completion, your property will pass all tests and requirements from a 3rd party industrial hygienist.


This time last week we were in London and had spent a lovely afternoon 1) walking along Regent's Canal east to Victoria Park where we had lunch, and then 2) continuing east to the Olympic Park. Today we went to an organ concert (Bach) in St Germain des Pres and then walked down to the Seine and east along the Right Bank quais to the bridge after the Pont Notre Dame and back. We would have gone to Mariage Freres for tea but we got lost in the labyrinth of streets and gave up looking for the right one--rue des Grands Augustins, I think. And home to a Scotch instead.
Yesterday evening we met friends for a drink rue Cler and walked home. I volunteered at the Soupe Populaire for lunch: it was cold and raining and the lunchers were pounding on the door to get in, especially if we were late, as we inevitably are. They could stand in the Arcades across the street in front of the Apple Store, but they don't want to miss their place in line (so to speak; mostly they crowd and push) and the security guards keep a close eye on our bunch. Dessert was apples from one or two of the 200 or so apple trees in the Luxembourg Garden orchards. I snuck one home.


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text:
Leah Bryan
When was the last time you set a career goal? Sometimes, it's easy to get complacent when you have a good, steady job and fail to set goals. But that's never advisable. When you have proper goals to strive for, you'll find you're much happier. Plus, you'll find that you're more successful in your job and your career as a whole.
Of course, simply saying you'll set a career goal and leaving it at that doesn't often work. It's too vague, too abstract. It's important to think critically about setting career goals so that you actually achieve success.
Here's something that may surprise you: Oftentimes, setting a career goal is more important than actually achieving the goal. That may sound strange, but think about it. When you have a goal to strive for, it gives you a sense of direction. It may not matter as much as you think whether you achieve the goal itself. It's the journey that benefits you as much as the achievement itself.
What are the benefits of setting career goals? How do you do it? Let's take an in-depth look at the process of setting goals for your career and how it can benefit you.
What Are The Benefits of Setting Career Goals?
You may wonder what the point of setting goals is at all. What if you just completed your daily tasks, did your best, and let your career take you where it takes you?
While there's nothing wrong with a little spontaneity, there are many benefits to setting career goals for yourself. Some of the advantages of this approach are:
It gives you direction. Without specific goals, you don't have much of a direction to your career. You're simply wandering through it aimlessly. And if that's how you want to approach it, you're more than welcome to. But don't expect to achieve success and advance in your career without setting concrete goals.
It helps you earn more. Whether you're advancing in the ranks or learning a new skill set to snag that promotion, setting career goals ultimately helps you earn more money. That's something almost everyone can get behind.
You'll have more motivation. Find yourself lacking motivation at work? Set a career goal. Giving yourself something to strive for every day simply feels good—you'll feel like your job has a purpose, rather than just being a number on a list.
Are There Different Types of Career Goals?
Yes, there are many different types of career goals. Don't make the mistake of thinking that your goals have to fall into a specific category or align with others' career goals.
Your career goals might involve a promotion, moving up in the ranks and gaining experience and influence at your company. On the other hand, your goals might have nothing to do with rank or money. Perhaps you simply want to find a career that brings you joy, or helps you get out from under your oppressive boss. Maybe you want to find a job and career that gives you time outside of work to focus on what you're passionate about, whether it's your family or a side hustle.
There are short-term and long-term goals, too. And those timeframes can be as short or long as you want them to be. Short-term goals can be as short as daily goals—what you will achieve this particular day at work, for example. Or, short-term goals could be over the next month, half-year, or year. Then there are long-term goals, like those you set to achieve over the next year or five years. It all depends on your circumstances and what you want to achieve out of your career.
How to Set Your Career Goals
We've learned that there are various benefits to setting career goals, and that there are all sorts of different goals that you may decide to set for yourself. The question is… how do you set career goals in such a way that it really works?
Break it down for yourself so that it's easier. There are five steps you can take, every time, to set a career goal for yourself: self-assess, brainstorm, research, get a new perspective, and set the goal.
Self-Assess
Think of this step as taking stock of where you are right now. What kind of position are you in? What are your current skills and interests? What traits do you possess that serve you well in your career? What is your work history like?
With all of that in mind, think about where you want to go. Is there a particular type of job you'd like to secure? A certain salary? A new skillset? A new career field entirely? Write down these items so that you have them top-of-mind for the next step.
Now, it's time to use the information you came up with in the self-assessment phase—thinking about where you are now and where you'd like to end up—to brainstorm some options. What kind of jobs would allow you to use your interests and skillset? What would you like be doing a year from now?
You can even take career quizzes (widely available online) or speak to a career counselor if you'd like. These options are great ways to learn more about a potential career field or particular jobs in your field.
Now that you've written down some options of where you want to take things with your career goals, it's time to do some research. Using the internet to learn more about certain positions or fields is always a good option. Learn more about where you want to go, and a clear picture will start to emerge of how to get there.
Say you want to get a promotion to a management position in your field. Do some research to learn about the job requirements for a manager in your industry; what the typical salary looks like; what the day-to-day responsibilities are. You'll be surprised how quickly a path to reaching your goal starts to emerge.
Online research isn't your only option, of course. You can try talking directly with people in the field, or connecting with a staffing firm like BOS Staffing to learn about a career field you're interested in.
Get Perspective
When setting your career goals, it's sometimes helpful to get a new perspective outside of your own. There are various ways you can do that. Say you're thinking of exploring a new career field that you'd like to be a part of in the next year. Volunteering in that field, or taking on an internship, or talking to someone in the field are all good options. You can even seek out a mentor in your chosen field who can give you an insider's perspective.
Set Your Goal
By now, you've assessed yourself and what you'd like to achieve, brainstormed some options, done research, and gained new perspectives. You're ready to set your goal.
Perhaps your career goal is now clear. Even if it is, it's wise to put some parameters on it. And one way to do that is with the SMART goal-setting system. SMART stands for:
Specific: Don't make your goal too abstract or vague. Ask yourself specifically what you want to achieve and orient your goal around that. For example, rather than saying "I want to make more money this year," say "I want to make three dollars more per hour this year."
Measurable: How can your goal be measured? In numbers? Time? Make it measurable so that you can check in on your progress throughout the process.
Attainable: While it's always great to shoot for the stars, make sure your goal is attainable at the same time. Be realistic about your goal; make it something you're sure you can achieve. Otherwise, you'll be left feeling disappointed.
Relevant: Make your goal relevant to your overall career trajectory, even if it doesn't have something to do with your career itself. For instance, if your goal is to spend less time working so that you can spend more time with your family, set a measurable, specific goal of how much you'd like to cut back at work. Relate your actions to your goal, or else it won't get you very far.
Time-bound: Goals without a timeframe are too easy to give up on, or never complete. Set a hard date when your goal will be achieved, and try setting check-in points along the journey to track your progress.
Reaching Your Career Goals
Now that you've defined and set your career goals, it's time to work on them. And remember: In some cases, the journey to get there is just as important as achieving the goal itself. If you don't achieve it but learn important things along the way, then it was worth it.
If you've set a SMART goal, you'll be able to track your progress and aim for your goal in a specified time frame. All that's left to do is put in the work and do your best.
Setting career goals for yourself gives you direction, it motivates you, and it benefits you financially and otherwise. And while career goals can take all sorts of different forms, your goals need to be specific, measurable, attainable, relevant, and time-bound. Do that, and you'll find yourself on the path to success sooner rather than later.
If you're in the market for a new job or career in Georgia, trust the experts at BOS Staffing. Get in touch with a member of our team today to learn more about what we offer.


text:
High-throughput sequencing of RNA isolated by crosslinking immunoprecipitation (HITS-CLIP) is a variant of CLIP for genome-wide mapping protein–RNA binding sites or RNA modification sites in vivo.  HITS-CLIP was originally used to generate genome-wide protein-RNA interaction maps for the neuron-specific RNA-binding protein and splicing factor NOVA1 and NOVA2; since then a number of other splicing factor maps have been generated, including those for PTB, RbFox2, SFRS1, hnRNP C, and even N6-Methyladenosine (m6A) mRNA modifications.

HITS-CLIP of the RNA-binding protein Argonaute has been performed for the identification of microRNA targets by decoding microRNA-mRNA and protein-RNA interaction maps in mouse brain, and subsequently in Caenorhabditis elegans, embryonic stem cells and tissue culture cells.

As a novel modification of HITS-CLIP, m6A-CLIP was developed to precisely map N6-Methyladenosine(m6A) locations in mRNA by UV-crosslinking m6A antibody to the target RNA. Recently, improved bioinformatics applied to Argonaute HITS-CLIP enables identification of binding sites with single nucleotide resolution.

Similar methods
PAR-CLIP, for identifying the binding sites of cellular RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) in tissue culture cells.
iCLIP, for a thorough amplification of the cDNA library, including truncated cDNAs, thus also enabling an additional means to identify crosslink sites.

References

External links
 CLIPSim-MC: CLIPSim-MC is a tool that uses CLIP-seq data to find miRNA/MRE pairings using a Monte-Carlo-based approach.
 starBase database: a database for exploring miRNA-mRNA, miRNA-lncRNA, miRNA-sncRNA, miRNA-circRNA, miRNA-pseudogene, protein-lncRNA, protein-RNA interactions and ceRNA networks from HITS-CLIP (CLIP-Seq, PAR-CLIP, iCLIP, CLASH) data, and TargetScan, PicTar, RNA22, miRanda and PITA microRNA target sites.
 clipz: a pipeline to analyze short RNA reads from HITS-CLIP experiments.
 dCLIP: dCLIP is a Perl program for discovering differential binding regions in two comparative CLIP-Seq (HITS-CLIP, PAR-CLIP or iCLIP) experiments.

RNA
Molecular genetics
MicroRNA


Today, I had the good fortune of being interviewed by Liz O'Dwyer of Business Success Radio.
We had met to discuss my afternoon with Seth Godin back in January 2, 2013, in New York City, which we did.
As is always the case though when talking about "The Icarus Deception" and Living your Art, my Art always comes into play… that being of working with Business Owners to start the process of Getting Out.


text:
Media multitaskers aren't that smart
Study from Stanford University shows that people juggling different media have trouble paying attention
Tags: Social networking, Stanford University, USA
Study from Stanford University shows that people juggling different media have trouble paying attention.
By Vineetha Menon Published August 26, 2009
People who are regularly exposed to electronic information are paying a mental price for it, a study by the Stanford University has revealed.
A hundred students took part in the study, undergoing three tests that separately analysed their ability to filter out irrelevant information, organise their memory and switch from one job to another.
In each of the tests, the researchers split their subjects into two groups: those who regularly do a lot of media multitasking and those who don't.
Researchers found that students who juggle different media such as the internet, television and mobile phones were unable to perform well in any of the tests in comparison to those that preferred to complete one task at a time.
Facebook is changing its news feed algorithm, again.
Instagram launches #MonthOfGood Movement and Ramadan camera effect
Snapchat announces advertising partners for commercials
Saudi cybersecurity centre signs MoU with Stanford
US researchers build battery that charges in one minute
"They're suckers for irrelevancy," said communication Professor Clifford Nass, one of the researchers involved in the study. "Everything distracts them."
High-tech jugglers are common these days – people have e-mail, IM and Twitter conversations at the same time, text message while watching television, and jump from one site to another while trying to complete an assignment.
"When they're in situations where there are multiple sources of information coming from the external world or emerging out of memory, they're not able to filter out what's not relevant to their current goal," said Wagner, an associate professor of psychology added. "That failure to filter means they're slowed down by that irrelevant information."
Social scientists have long assumed that it's impossible to process more than one string of information at a time but researchers argued that people who multitask must have superb control over what they think about and what they pay attention to, which this study now disputes.
Honeywell launches online store for business-critical software
Internet Society's Online Trust Alliance says cyber incidents cost $45B in 2018
Grade hacking services and fake diplomas easily available online during exam season


Where can I find info an what gearboxs & ratios are for country buggies? What RPM will they cruise at 100kph with reduction boxes?
Here's a copy of a page from "Without Guesswork 1969" that shows speed for engine revs for Type 2s.
A Country Buggy's gearbox & wheels are from the last type 2 with reduction hubs so that will be correct. Looks like about 100ks at 4K. They were never fast, but pretty quick, especially off road.
Parts book doesn't show the gear ratios, just the part number.
I've also attached the page on ratios from Without Guesswork 1969.


Discussion in 'E-mail Discussion' started by kistler, Apr 4, 2006.
It means you have messages in the mail queue that could not be delivered to the recipient for one reason or another and that the time interval to try to resend thos messages has not been reached therefore they will be left frozen until that time is reached.
DNS issues all cleaned up now, it looked ok, so i tried other tweeks.


A Page Association represents an association between two public pages (see Page) and is used for sharing content between pages. The direction of the Page Association has meaning and indicates that the from_page has associated itself with the to_page, allowing social posts from the to_page to appear on the from_page.
To create an association between pages, the User creating the association must have edit_resource permission on Page Associations.
GET Get a list of Page Associations. POST Create a Page Association. (edit_resource permission on Page Associations is required).
Note: Both parameters can be used together to determine if there is an association of the specified direction between two pages.
Returns a single result if there is an association of this direction between two pages, otherwise returns an empty list.


Warming Up looks at what goes on behind the scenes of musical performance, the social ties and spaces, things and practices that produce and sustain a creative community. The title makes a connection between the preparation for recording or going onstage and the warmth of social relationships. Warmth is a physical sensation, but also a metaphor that refers here to the heightened creative possibilities produced by interaction, by exchanging and bouncing ideas off one another.
Getting through a Prince Edward Island winter is difficult enough. For musicians facing fewer gigs and a hibernating population, a close-knit community is necessary to sustain a vibrant music scene. This exhibition project began when photographer Anna Karpinski decided to document that community in a formal group photograph of Island musicians entitled Something in the Water. Taken in the dead of winter, the picture records 76 well-known Island musicians gathering in front of Province House. Millefiore Clarkes' video of the Karpinski photo shoot captures the conversations and movements of a bustling crowd of musicians assembling before and after the event in an array of interlocking frames that register the fluidity of the relationships explored. In her wall drawing Constellation, Becka Viau presents the results of research into the network of P.E.I. musicians, who replied to herquestion, "Can you list your solid creative connections?" The drawing represents these connections as a non-linear, non-hierarchical, yet still cohesive mass of intricate patterns. In a nod to the spaces that sustain creativity, Kelly Caseley, known as a fashion designer and co-owner of The Green Man Vintage and Vinyl in Charlottetown, has created an interactive setting/lounge that pays tribute to the material dimension of music-making, and also offers a space for hanging out and making music with instruments and sound equipment. Halifax-based artist and musician Eleanor King provides a counterpoint to the celebratory side of Warming Up. Her drum-based installation piece, Endless Practice, reminds us that the repetitive, sometimes tedious activity of practice (the title also plays on the notion of "artistic practice") is another integral part of what binds musicians together. And her sculptural column of drums demonstrates how a formal statement can be built, literally, by combining everyday elements by means of processes we normally consider mundane, such as stacking and lining things up in rows. This exhibition pays tribute to those connections, communities, spaces and things that help make possible the experience of musical performance.
This exhibition would not have been possible without the help of many individuals and organizations. The Confederation Centre Art Gallery and the artists in Warming Up wish to acknowledge the valuable assistance of Adam Gallant, Overman, Linda Wigmore, Racoon Bandit, Lee Clarke, Soleil Hutchinson, Rachael Hicken, Allison Cooke, and Steve Gillespie. The ECMA Arts Linkages Program, funded through the Cultural Capital Designation and the City of Charlottetown, provided generous assistance in the documentation of this exhibition project.


Our Newly Redesigned Blue Mountain Website is Here!
We were very excited to roll out our redesigned Blue Mountain website last week and hope you're all getting a chance to enjoy it! We have a helpful page for you that explains some of the changes that were made to the site based on the surveys and questionnaires you responded to as well as the feedback you've given us this past year. Just click on the following link to view.
that features our most popular cards to share with your friends and family.
and, when you get a chance, send us a comment and let us know what you think!


text:
Eboni Booth's Paris Opens at Atlantic Theater Company
The world premiere, directed by Knud Adams, marks the professional playwriting debut of playwright and performer Booth.
Read Reviews for the New Off-Broadway Musical Emojiland
See what critics think of the musical comedy, starring Ann Harada, George Abud, Lesli Margherita, Lucas Steele, and many more.
What Did Critics Think of Off-Broadway's Gender-Swapped Timon of Athens?
By Ryan McPhee | 01/21/2020
The Theatre for a New Audience production opened January 19.


text:
Source: WHO Regional Office for Africa | Nov 03, 2022
The greater Horn of Africa's climate-related health crisis worsens as disease outbreaks surge
In most countries of the region, measles vaccination coverage is too low to prevent cases and all greater Horn of Africa countries have had to deal with measles outbreaks in 2022
New analysis by World Health Organization (WHO) has found that the number of reported disease outbreaks and climate-related health emergencies in the greater Horn Africa have reached their highest-ever level this century, deepening a health crisis in a region where 47 million people are already facing acute hunger. Most parts…
Multimedia content
Nurse Peace (right) counsels a patient before she gets screened for cervical cancer at the RAiSE Foundation office in Niger State on 24 February 2021
Deaths from noncommunicable diseases on the rise in Africa
The rising burden of noncommunicable diseases will exert pressure on treatment and care services
Noncommunicable diseases such as cancer, cardiovascular diseases and diabetes are increasingly becoming the main cause of mortality in sub-Saharan Africa, where the diseases were responsible for 37% of deaths in 2019, rising from 24% in 2000 largely due to weaknesses in the implementation of critical control measures including prevention, diagnosis…
Stronger Governance Needed to Fight Superbugs in Africa: Antimicrobial Resistance threatens Africa's Development
Addressing AMR requires an holistic and multi-sectoral approach
The leaders of six regional organizations in Africa are calling for stronger governance to fight antimicrobial resistance, or AMR, on the eve of World Antimicrobial Awareness Week (18-24 November). The emergence and spread of antimicrobial resistance in Africa – where micro-organisms such as bacteria, viruses, fungi and parasites are resistant…
Engr Hassan Musa, Parmananent Secretary, Federal Ministry of Environment at the UN Day symposium
Source: WHO Regional Office for Africa | Oct 26, 2021
UN Reaffirms Commitment to Ensuring Peace and Prosperity for all in Nigeria
Due to the pandemic, millions of Nigerians have been devastatingly affected through the loss of lives and livelihoods
The United Nations System in Nigeria has reaffirmed its commitment to ensuring peace and prosperity for all in Nigeria. This commitment was made by Dr Walter Kazadi Mulombo, the World Health Organization (WHO) Country Representative and United Nations Resident Coordinator (Ad Interim) during a symposium to commemorate the 2021 UN…
Source: WHO Regional Office for Africa | Sep 24, 2020
Coronavirus: Social, environmental factors seen behind Africa's low COVID-19 cases
Deaths attributed to COVID-19 have also remained low in the region
COVID-19 transmission in Africa has been marked by relatively fewer infections, which have been on the decline over the past two months, owing to a variety of socio-ecological factors as well as early and strong public health measures taken by governments across the region. The pandemic has largely been in…
Source: WHO Regional Office for Africa | Aug 10, 2020
Coronavirus - Mauritius: Promoting and Protecting Breastfeeding for a better start in Life
The country aims at creating awareness among young people on the importance of breast feeding and its positive contribution to a healthier planet
Mauritius marked World Breastfeeding Week 2020 by an official ceremony performed by Minister of Health and Wellness, Dr Hon. Kailash Jagutpal on 06 August 2020 at the Victoria Hospital, Candos. In line with this year's theme, the country aims at creating awareness among young people on the importance of breast…
Source: WHO Regional Office for Africa | May 13, 2020
Ghana Bolsters Medicines Regulatory System, Guarantees Product Quality
Ghana and Tanzania are the only two of World Health Organization (WHO) African Region's 47 countries to have attained a Level 3 ranking
Ghana has strengthened its medicines regulatory system to ensure safety, quality and effectiveness of medical products manufactured, imported or distributed within the country, the World Health Organization (WHO) announced today. Ghana becomes the second country in the WHO African Region to attain regulatory system "Maturity Level 3" – the second-highest…
WHO Representative to Namibia, Dr Charles Sagoe-Moses handing over the COVID-19 medical supplies to the Minister of Health and Social Services, Dr Kalumbi Shangula
Coronavirus - Namibia: WHO supports supplies for front line health workers
Health care workers are at the front line of the COVID-19 outbreak response and as such are exposed to hazards that put them at risk of infection
The first United Nations 'Solidarity' flight started delivering vital medical supplies from last week to all countries in Africa where these are needed the most. The flight was facilitated by the World Food Programme and included WHO supported supplies of face shields, gloves, goggles, gowns, masks, medical aprons and thermometers. Supplies for…
West and Central Africa Expands Access to HIV Treatment, But Falls Short of Targets (1)
Source: WHO Regional Office for Africa | Dec 04, 2019
West and Central Africa Expands Access to HIV Treatment, But Falls Short of Targets
At the end of 2018, 53% of adults (people aged 15 and over) were accessing antiretroviral therapy (ART), compared to 39% in 2015
West and Central Africa has made significant progress in expanding access to HIV treatment in the past three years. At the end of 2018, 53% of adults (people aged 15 and over) were accessing antiretroviral therapy (ART), compared to 39% in 2015[i]. However, the region still lags behind East and Southern…
Antimicrobial resistance on his own leg turns a Kenyan health worker into an advocate for wiser use of antibiotics (1)
Antimicrobial resistance on his own leg turns a Kenyan health worker into an advocate for wiser use of antibiotics
When the thigh wound grew bigger, the health worker, being well versed in the perils of contagion, feared it would trigger an internal infection
Josphat, a health worker based in Nairobi, needed a skin graft on his leg in 2013. But then, what is typically a common procedure nowadays became a medical nightmare. The donor site on his thigh took longer to heal than expected and was nonresponsive to conventional antibiotics. Laboratory tests revealed…
@WHOAFRO 1 hour ago
RT @WHONigeria: WHO NTD road map 2021-2030 focuses on the value of integrating NTD programmes, establishing links w/ other sectors (educati…
RT @WHONigeria: Despite the global COVID-19 pandemic, progress has been achieved during the two years since the publication of the 2021-203…
RT @WHONigeria: Access to medicines, diagnostics, and essential technologies for NTDs should be sustained and expanded, including through d…
RT @WHONigeria: With increased investment, action & collaboration, countries can beat NTDs. NTD programmes are cost-effective interventions…


I mailed my ballot back on Friday, with The Granite State as my first pick.
I'll see you all in the Free State!
I close my eyes and maybe I'm already there"
What's with all of these "two votes" and "four votes" people?
You have TWO or FOUR ACTIVISTS in your household?
I could have easily signed up my wife and had her vote, but she's not an activist, so that would be dishonest manipulation of the vote.
Hopefully everyone is being honest here by only signing up those who are activists. Otherwise you're only hurting our cause.
There are all activist voters!
Based on the total number of votes, it is impoosible to tell who the winner is. NH obviously took the most first place votes, however because it didn't get an absolute majority, it's theoretically possible that another state won. 32 votes are available and only 23 above NH would be needed. WY already has 10 (would need as few as 13 votes above NH), and ID already has 7 (would need as few as 16 votes above NH). I didn't look at the total votes for those who reported more than one (since the thread is only about first place votes) but there were some that ranked WY, ID, AK, and MT above NH but below first place. Hence, I wouldn't say it's 'in the bag' for NH, though it appears to be heavily weighted that way.
3 activists voting from this household.
My count matched yours, varrin, but that could just mean we're both wrong!
Thanks for the confirmation Bruce. I was hoping I counted correctly. Based on the below, NH moves closer to an absolute majority. I wonder how the non-participants will vote (compared with those of us who frequent these forums). If it's anywhere close, it looks like NH will win by a healthy margin.
As you can see (in all this unscientific stuff), my ranking of VT was off. Did *anyone* put VT first? I can't believe someone fessed up to putting ND first and not VT. Regardless, I got the first three in the right order and I'm willing to bet that the actual outcome will be either NH > WY > ID or NH > ID > WY. I'll be a little surprised if AK comes in 4th, but on this thread it is. I'll also be a little surprised if ND beats VT and if SD doesn't beat ME.
IMNSHO, VT is actually quite ripe for a lib infusion, but they don't have the infrastructure, people or experience that NH does. Plus, it's a longer road to travel as far as economic issues are concerned.


Some of these resources may contain offensive language or negative stereotypes. Such materials should be seen in the context of the time period and as a reflection of attitudes of the time. The items are part of the historical record, and do not represent the views of the libraries or the institution.
Its music on my hear.
To win her much lov'd boy.
In the swelling of my heart.
Will be thy gentle song.
And it's music in my heart.
Taylor, James B., "O Sing to me One Son of Thine" (1834). Historic Sheet Music Collection. 450.


text:
Currently Viewing The Case for Polarized Politics $25.95
The Case for Polarized Politics
Why America Needs Social Conservatism
By Jeffrey Bell
Hardcover / 328 pages
AVAILABLE: 3/6/2012
Because no movement resembling American social conservatism exists in any other affluent democracy, it is widely seen as a "retro" phenomenon soon to disappear, a sure casualty of globalization.
Author and political activist Jeffrey Bell argues that social conservatism is uniquely American precisely because it's an outgrowth of American exceptionalism. It exists here because our founding principles, centering on the belief that we receive equal rights from God rather than from government, remain popular among American voters—if not at elite institutions.
Bell argues that upheavals of the 1960s set the stage for social conservatism's rise. The left's agenda, particularly the sexual revolution, triumphed among elite opinion in the U.S., Europe, Japan, and elsewhere. This happened after the left sidelined its century-long drive for socialism and returned to its roots in the 18th-century thought of Rousseau and the revolutionary Jacobins, radicals who sought to break free from civilizing institutions, particularly religion and the family.
American social conservatism derives from a branch of the Enlightenment that Bell analyzes as the "conservative enlightenment." The ability of this optimistic belief system, which dominated the American founding and transformed the English-speaking world, to spread its natural-law-centered vision of democracy will affect the shape of politics in the decades ahead.
Jeffrey Bell played an active role in federal tax budget reform as an aid to Ronald Reagan in the 1970s and 1980s. He presently serves on the Board of Directors of the American Conservative Union and of the Campaign Finance Institute at George Washington University.
Why Liberals and Conservatives Will Never, Ever Agree
William D. Gairdner
The theme of The Great Divide is that the populations of the democratic world, from Boston to Berlin, Vancouver to Venice, are becoming increasingly divided from within, due to a growing ideological incompatibility between modern liberalism and conservatism.
Patriotism Is Not Enough
Harry Jaffa, Walter Berns, and the Arguments that Redefined American Conservatism
Steven F. Hayward
This book is a lively intellectual history of a small circle of thinkers, especially, but not solely, Harry Jaffa and Walter Berns, who challenged the "mainstream" liberal consensus of political science and history about how the American Founding should be understood.
America's Limitless Welfare State
Since the beginning of the New Deal, American liberals have insisted that the government must do more—much more—to help the poor, to increase economic security, to promote social justice and solidarity, to reduce inequality, and to mitigate the harshness of capitalism.
Conservatism Redefined
A Creed for the Poor and Disadvantaged
Patrick M. Garry
Throughout the 1980s and 1990s, conservatism possessed a vibrancy that resulted from spirited intellectual inquiry and open debate. However, in the years leading up to the 2008 elections, this energy seemed to fade.
Shattered Consensus
The Rise and Decline of America's Postwar Political Order
James Piereson
Are we on the verge of another upheaval, a "fourth revolution" that will reshape U.S. politics for decades to come? There are signs to suggest that we are.
The Perils & Promises of Populism
The rise of populist movements across the political spectrum poses a vital question: what role should populism play in modern democracy? In ten trenchant essays, the writers of The New Criterion examine the perils and promises of populism in Vox Populi, a new collection that marks the thirty-fifth anniversary of this critical journal.


text:
We are Catalysts for the Entrepreneurial Dream
We are fully committed to helping entrepreneurs achieve the dreams they have for their businesses. That has been our sole purpose for the past 25+ years – whether we're working directly with the business owner, a lender, or an economic development organization.
Catalysts for the Entrepreneurial Dream
For more than a quarter century, we have helped entrepreneurs like you obtain the financing they need to realize their business dreams. We are a non-profit, small business lender that offers SBA 504 and SBA 7(a) Community Advantage loans, and we administer the City of Chicago's Small Business Improvement Fund (SBIF) and Neighborhood Opportunity Fund (NOF) grants.
Behind every good business is a compelling vision. And a need for capital. Our purpose is to guide your vision to reality through impactful financial solutions. That's because business growth, job creation and community impact are our priorities.
Values Oriented
We get how tough it can be. That's why we never forget compassion, patience and honesty when we work with you. With our lending partners, we work efficiently and ethically to provide outstanding customer service and tangible results.
We are catalysts for the entrepreneurial dream. We assist in bringing the entrepreneurial vision into reality through impactful financial solutions. We help businesses grow and positively impact the owners, employees and communities.
We seek to become a national leader in SBA lending and economic development; thereby helping as many Americans as possible take the next steps towards fulfilling their entrepreneurial dreams.
We care about our clients and believe in treating them with compassion, integrity, fairness and honesty. We work efficiently and ethically with our partners to provide outstanding customer service and tangible results. In doing so, we have the greatest positive impact on our clients, their businesses, employees and communities.
The significance of a mission-based Certified Development Company
With a portfolio of nearly $500 million, SomerCor is one of the largest SBA lenders in the Midwest, consistently ranking in the top 25 Certified Development Companies (CDC's) nationwide. We are a mission-based, nonprofit corporation certified by the Small Business Administration (SBA). Our mission is accomplished through SBA loans in partnership with lenders, and through the administration of grant funds through economic development organizations.
That mission is three-fold:
The numbers speak for themselves
$1.48 billion in funding for Illinois small business
3,500 businesses helped
41,400 jobs created
1,608 communities affected
SomerCor Significant Events
JULY: SomerCor 504, Inc is incorporated
JULY: Karen Lennon elected President & Executive Director, first woman to create and lead an Illinois CDC
SomerCor moves into its first location at Two East 8th Street, Chicago, IL 60605
SEPT: Portfolio hits $100,000,000
SEPT: City of Chicago enters into an agreement with SomerCor to administer the SBIF program
SEPT: City of Chicago enters into an agreement with SomerCor to administer the Central Loop Improvement Fund program
JAN: Russ Lenich elected President & Executive Director
SomerCor is awarded the Arthur Goodman Achievement and Diversity Award for the Small Business Improvement Fund by NADCO
DEC: Portfolio hits $250,000,000
MAY: SomerCor moves into its current location at 601 S. LaSalle Street,
Suite 510, Chicago IL
JUNE: David Frank elected President & Executive Director
SomerCor is awarded the Greatest Increase in Number of 504 Loan Approvals – Portfolio over $200 Million by NADCO
SomerCor is awarded the Greatest Increase in Percentage of 504 Loan Approvals – Portfolio over $200 Million by NADCO
NOV: SomerCor is named one of the Largest SBA Lenders by Crain's Chicago Business
APR: U.S. Small Business Administration enters into an agreement with SomerCor to become a Community Advantage lender
SomerCor is awarded the NADCO Diamond Award for Innovation in Economic Development
NOV: Eric Spokas elected President & Executive Director
FEB: City of Chicago enters into an agreement with SomerCor to administer the NOF program
MAY: SomerCor is awarded the Illinois Community Advantage Lender of the Year by the U.S. SBA
NOV: Manuel "Manny" Flores elected President & SomerCor's first Chief Executive Officer; first Latino to lead an Illinois CDC
JAN: SomerCor achieves official accreditation with an A+ rating from the Better Business Bureau


Kriss Hawk is creating Dance, Art, Lifestyle.
My journey is about seeking the truth and learning myself, reaching my highest potential i possibly can, I wish to help the world and inspire people that dream big to start doing what they love, to be free! And if i can do it, then you can aswell!


text:
#ifndef _OLSRD_CFG_H
#define _OLSRD_CFG_H

/* Default values not declared in olsr_protocol.h */
#define DEF_POLLRATE           50
#define DEF_NICCHGPOLLRT       2500
#define DEF_WILL_AUTO          true
#define DEF_ALLOW_NO_INTS      true
#define DEF_TOS                16
#define DEF_DEBUGLVL           "0"
#define DEF_IPC_CONNECTIONS    0
#define DEF_FIB_METRIC         FIBM_FLAT
#define DEF_LQ_ALWAYS_SEND_TC  true
#define DEF_LQ_FISH            0
#define DEF_LQ_DIJK_LIMIT      255
#define DEF_LQ_DIJK_INTER      0
#define DEF_LQ_NAT_THRESH      1000
#define DEF_CLEAR_SCREEN       false
#define DEF_HTTPPORT           8080
#define DEF_HTTPLIMIT          3
#define DEF_TXTPORT            2006
#define DEF_TXTLIMIT           3

/* Bounds */

#define MIN_INTERVAL        0.01

#define MAX_POLLRATE        10000
#define MIN_POLLRATE        10
#define MAX_NICCHGPOLLRT    100000
#define MIN_NICCHGPOLLRT    1000
#define MAX_DEBUGLVL        3
#define MIN_DEBUGLVL        -2
#define MAX_TOS             16
#define MAX_WILLINGNESS     7
#define MIN_WILLINGNESS     0
#define MAX_MPR_COVERAGE    20
#define MIN_MPR_COVERAGE    1
#define MAX_TC_REDUNDANCY   2
#define MAX_HYST_PARAM      1.0
#define MIN_HYST_PARAM      0.0
#define MAX_LQ_AGING        1.0
#define MIN_LQ_AGING        0.01

/* Option values */
#define CFG_FIBM_FLAT          "flat"
#define CFG_FIBM_CORRECT       "correct"
#define CFG_FIBM_APPROX        "approx"

#define CFG_IP6T_AUTO          "auto"
#define CFG_IP6T_SITELOCAL     "site-local"
#define CFG_IP6T_UNIQUELOCAL   "unique-local"
#define CFG_IP6T_GLOBAL        "global"

#define OLSR_IP6T_AUTO         0
#define OLSR_IP6T_SITELOCAL    1
#define OLSR_IP6T_UNIQUELOCAL  2
#define OLSR_IP6T_GLOBAL       3

#ifndef IPV6_ADDR_GLOBAL
#define IPV6_ADDR_GLOBAL       0x0000U
#endif

#ifndef IPV6_ADDR_SITELOCAL
#define IPV6_ADDR_SITELOCAL    0x0040U
#endif

#include "interfaces.h"
#include "olsr_ip_acl.h"
#include "olsr_cfg_data.h"

struct olsr_msg_params {
  uint32_t emission_interval;
  uint32_t validity_time;
};

struct olsr_lq_mult {
  union olsr_ip_addr addr;
  uint32_t value;
  struct olsr_lq_mult *next;
};

struct olsr_if_weight {
  int value;
  bool fixed;
};

struct olsr_if_options {
  union olsr_ip_addr ipv4_broadcast;
  int ipv6_addrtype;
  union olsr_ip_addr ipv6_multi_site;
  union olsr_ip_addr ipv6_multi_glbl;
  struct olsr_if_weight weight;
  struct olsr_msg_params hello_params;
  struct olsr_lq_mult *lq_mult;
  bool autodetect_chg;
  enum interface_mode mode;
};

struct olsr_if_config {
  char *name;
  char *config;
  struct interface *interf;
  struct olsr_if_options *cnf;
  struct olsr_if_config *next;
};

struct plugin_param {
  char *key;
  char *value;
  struct plugin_param *next;
};

struct plugin_entry {
  char *name;
  struct plugin_param *params;
  struct plugin_entry *next;
};

typedef enum {
  FIBM_FLAT,
  FIBM_CORRECT,
  FIBM_APPROX
} olsr_fib_metric_options;

/*
 * The config struct
 */

struct olsr_config {
  int ip_version;                      /* AF_INET of AF_INET6 */
  size_t ipsize;                       /* Size of address */

  unsigned char no_fork:1;             /* Should olsrd run in foreground? */
  unsigned char allow_no_interfaces:1; /* Should olsrd stop if no ifaces? */
  unsigned char willingness_auto:1;    /* Willingness in auto mode? */
  unsigned char clear_screen:1;        /* Clear screen during debug output? */
  unsigned char del_gws:1;             /* Delete InternetGWs at startup? */
  unsigned char fixed_origaddr:1;      /* Use a fixed originator addr == Node ID? */
  unsigned char source_ip_mode:1;      /* Run OLSR routing in sourceip mode */

  uint16_t tos;                        /* IP Type of Service Byte */
  uint8_t rtproto;                     /* Policy routing proto, 0 == operating sys default */
  uint8_t rttable;                     /* Policy routing table, 254(main) is default */
  uint8_t rttable_default;             /* Polroute table for default route, 0==use rttable */
  olsr_fib_metric_options fib_metric;  /* Determines route metrics update mode */

  /* logging information */
  bool log_event[LOG_SEVERITY_COUNT][LOG_SOURCE_COUNT]; /* New style */
  bool log_target_stderr;              /* Log output to stderr? */
  char *log_target_file;               /* Filename for log output file, NULL if unused */
  bool log_target_syslog;              /* Log output also to syslog? */

  struct plugin_entry *plugins;        /* List of plugins to load with plparams */
  struct list_node hna_entries;        /* List of manually configured HNA entries */
  struct olsr_if_config *if_configs;   /* List of devices to be used by olsrd */

  uint32_t pollrate;               /* Main loop poll rate, in milliseconds */
  uint32_t nic_chgs_pollrate;      /* Interface poll rate */
  uint32_t lq_nat_thresh;              /* Link quality NAT threshold, 1000 == unused */
  uint8_t tc_redundancy;               /* TC anncoument mode, 0=only MPR, 1=MPR+MPRS, 2=All sym neighs */
  uint8_t mpr_coverage;                /* How many additional MPRs should be selected */
  uint8_t lq_fish;                     /* 0==Fisheye off, 1=Fisheye on */
  uint32_t lq_dinter;              /* Dijkstra Calculation interval */
  uint8_t lq_dlimit;                   /* Dijkstra Calculation limit */
  uint8_t willingness;                 /* Manual Configured Willingness value */

  uint16_t olsr_port;                  /* port number used for OLSR packages */
  char *dlPath;                        /* absolute path for dynamic libraries */

  uint16_t comport_http;               /* communication port for http connections */
  uint16_t comport_http_limit;         /* maximum number of connections (including interactive ones) */
  uint16_t comport_txt;                /* communication port for txt connections */
  uint16_t comport_txt_limit;          /* maximum number of interactive connections */

  struct olsr_msg_params tc_params;
  struct olsr_msg_params mid_params;
  struct olsr_msg_params hna_params;

  /*
   * Someone has added global variables to the config struct.
   * Because this saves binary link info we keep it that way.
   * ========= Please add globals below this line. =========
   */

  union olsr_ip_addr router_id;        /* Main address of this node */
  uint32_t will_int;                      /* Willingness update interval if willingness_auto */
  int exit_value;                      /* Global return value for process termination */

  int ioctl_s;                         /* Socket used for ioctl calls */
#if defined linux
  int rts_linux;                       /* Socket used for rtnetlink messages */
#endif
#if defined __FreeBSD__ || defined __MacOSX__ || defined __NetBSD__ || defined __OpenBSD__
  int rts_bsd;                         /* Socket used for route changes on BSDs */
#endif
};

/*
 * Global olsrd configuragtion
 */
extern struct olsr_config *EXPORT(olsr_cnf);

/*
 * Interface to parser
 */

typedef enum {
  CFG_ERROR,                           /* Severe parsing error, e.g. file not found, mixed up args */
  CFG_WARN,                            /* Non-severe error, e.g. use of deprecated option */
  CFG_EXIT,                            /* Given options will exit() e.g. "--version" or "--help" */
  CFG_OK                               /* Config is parsed and does not have any errors */
} olsr_parse_cfg_result;

olsr_parse_cfg_result olsr_parse_cfg(int argc, char *argv[], const char *file, char *rmsg, struct olsr_config **rcfg);
struct olsr_if_options *olsr_get_default_if_options(void);
struct olsr_config *olsr_get_default_cfg(void);
int olsr_sanity_check_cfg(struct olsr_config *cfg);
void olsr_free_cfg(struct olsr_config *cfg);

#endif /* _OLSRD_CFG_H */

/*
 * Local Variables:
 * c-basic-offset: 2
 * indent-tabs-mode: nil
 * End:
 */

redpajama_set_name: RedPajamaGithub