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According to the International Standard Classification of Education (ISCED), basic education comprises the two stages primary education and lower secondary education.

Universal basic education

Basic education featured heavily in the 1997 ISCED document, but the term was not included in the glossary. Each country interpreted the term in different ways, and leading up to the 2011 revision, a discussion paper was issued to seek clarification.

In most countries, ISCED 1 corresponds to the nationally designated primary education, and basic education includes that and also ISCED 2 lower secondary education (the lower level of secondary school). In other countries, where there is no break between primary and lower secondary education "basic education" covers the entire compulsory school period. For statistical reasons, ISCED 1 is then considered to be the first six years of schooling.

Universal basic education is regarded as a priority for developing countries and is the focus of the Education For All movement led by UNESCO. It is also included in the Millennium Development Goals as goal number 2: achieve universal primary education by 2015.

An extensive number of studies have proven its benefits for public health (e.g. lower spread of HIV/AIDS; better vaccination; prevention and medication of disease; better nutrition; lower maternal, infant, and child mortality),  demography (e.g. longer life expectancy, accelerated demographic transition through better birth control) and the economy (e.g. increased purchase power, increased productivity in traditional sectors, increased demand on service sectors). Other benefits, although more difficult to measure, include a beneficial impact on democracy, human rights, governance, and political stability through increased understanding of non-violent ways to solve problems and mutual understanding between groups in conflict.

The Convention on the Rights of the Child (CRC), established by UNICEF in 1989, protects children's inalienable rights by setting standards for multiple issues, one of which is education.

Gender equality in basic education

Gender equality in education has traditionally been narrowly equated with gender parity at different levels of formal education. Gender has been a traditional factor of inequality and disparity in education, most often to the disadvantage of girls and women. Yet there has been  significant progress in narrowing the gap around the world since 2000, with a larger proportion of girls and women accessing different levels of formal education. Indeed, gender parity in primary education has been achieved in Central and Eastern Europe, Central Asia, East Asia and the Pacific, Latin America and the Caribbean, North America and Western Europe. In addition, significant progress has been made since 2000 in narrowing the gender gap, particularly in South and West Asia and to a lesser degree in sub-Saharan Africa and the Arab States. However, despite the significant progress made, the majority of out-of-school children are girls, while two-thirds of youth and adults with low levels of literacy in the world are women. To help ensure women's empowerment, boys and men must also be engaged in the fight against gender inequality. This must begin with basic education.

See also
 International Standard Classification of Education
 K–12 (education)
 Educational stage
 Primary education
 Secondary education

Sources

References

External links
 Unicef
 Teachers First
 UNESCO

Secondary education
Primary education
Early childhood education
Educational stages
Education in India


Baxter Harries are delighted and extremely proud to announce that our own managing director Deborah Baxter has been shortlisted for a prestigious award; the Legal 500 Individual of the Year award 2018, within the London private client sector.
Deborah, who leads our Children Law team, has been rightly recognised as being an outstanding solicitor-advocate within her field.
Inclusion within the short listing of only 8 people is a huge honour and testament to Deborah's expertise and leading presence within the Private Client sector.


Your Fresno A/C system cools your home in much the same way a refrigerator keeps your food cool and fresh, but removing unwanted heat energy. This requires free airflow and all A/C components to be well-maintained and working in sync. If your A/C is blowing hot air and it's spoiling your comfort, give these troubleshooting tips a try.
Any air conditioner sounds other than the soft whoosh of cool comfort flowing through the vents should draw your attention. They may not turn out to be mechanically significant, but noise that persists should be checked out by a qualified HVAC technician before it becomes more than a simple annoyance.
After a long, hot summer, it's time to put fall maintenance on your calendar to save energy and increase your indoor comfort. The improvements you make will last well beyond the heating season, and not only will they lower your energy bills, they may also improve your indoor air quality.


Modern minimalist bangle bracelet made of colored copper wire.The region of the abstract, geometric, art to wear a bracelet, is 31cm (12,2in). The wire bangle wrap bracelet is adjustable to every hand.You can easily change the shape of the boho, summer, gift for her. Choosing different colors each time you can have unique appearances!
The price is about four bracelet.
Here are the links for one, two, three or five.


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News: Has the Location of the Center City of Atlantis Been Identified?
http://www.mysterious-america.net/hasatlantisbeenf.html
June 30, 2008 - Today In History
Atlantis Online > Forum > Atlantis Online - Messages > Commemorating Dates in History > June 30, 2008 - Today In History
Author Topic: June 30, 2008 - Today In History (Read 155 times)
Today is Monday, June 30, the 182nd day of 2008. There are 184 days left in the year.
Today's Highlight in History:
One hundred years ago, on June 30, 1908, the Tunguska Event took place in Russia as an asteroid exploded above Siberia, leaving 800 square miles of scorched or blown-down trees.
On this date:
In 1294, Jews are expelled from Berne Switzerland
In 1397, Denmark, Norway and Sweden sign Union of Kalmar under Queen Margaretha
In 1548, Emperor Charles V orders Catholics to become Lutherans
In 1834, Congress creates Indian Territory (now Oklahoma)
In 1859, French acrobat Blondin (born Jean Francois Gravelet) walked a tightrope above the gorge
of Niagara Falls as thousands of spectators watched.
In 1891, National Forest Service organized
In 1894, London Tower Bridge opens
In 1906, President Theodore Roosevelt signed the Pure Food and Drug Act and the Meat Inspection Act.
In 1921, President Harding nominated former President Taft to be chief justice of the United States,
to succeed the late Edward Douglass White.
In 1934, Adolf Hitler carried out his "blood purge" of political and military rivals in Germany in what
came to be known as "The Night of the Long Knives."
In 1936, the novel "Gone with the Wind" by Margaret Mitchell was published in New York.
In 1940, U.S. Fish and Wildlife Service forms
In 1958, the U.S. Senate passed the Alaska statehood bill by a vote of 64-20.
In 1963, Pope Paul VI was crowned the 262nd head of the Roman Catholic Church.
In 1971, The 26th Amendment, which lowered the voting age to 18, was ratified by the states.
In 1971, a Soviet space mission ended in tragedy when three cosmonauts aboard Soyuz 11 were
found dead inside their spacecraft after it had returned to Earth.
In 1985, 39 American hostages from a hijacked TWA jetliner were freed in Beirut after being held
In 1986, the Supreme Court, in Bowers v. Hardwick, ruled 5-4 that states could outlaw homosexual
acts between consenting adults. (However, the nation's highest court effectively reversed
this decision in 2003 in Lawrence v. Texas).
Ten years ago: Officials confirmed that the previously unidentified remains of a Vietnam War
serviceman buried in the Tomb of the Unknowns at Arlington National Cemetery
were those of Air Force pilot Michael J. Blassie.
Five years ago: Israeli and Palestinian commanders shook hands as bulldozers dismantled check-
points and Palestinian traffic flowed freely in the Gaza Strip. Comedian
One year ago: Two men rammed a jeep loaded with gasoline canisters into the main terminal at
Glasgow Airport in Scotland, failing to set off an explosion, but seriously burning
one of suspects; the attack came a day after two cars rigged as bombs were found
in London.
Today's Birthdays:
Singer Lena Horne is 91.
Actor Tony Musante is 72.
Actress Nancy Dussault is 72.
Singer Glenn Shorrock is 64.
Jazz musician Stanley Clarke is 57.
Actor David Garrison is 56.
Rock musician Hal Lindes (Dire Straits) is 55.
Actor-comedian David Alan Grier is 53.
Actor Vincent D'Onofrio is 49.
Actress Deirdre Lovejoy is 46.
Actor Rupert Graves is 45.
Boxer Mike Tyson is 42.
Rock musician Tom Drummond (Better Than Ezra) is 39.
Actor Brian Bloom is 38.
Actor Brian Vincent is 38.
Actress Monica Potter is 37.
Actor Rick Gonzalez is 29.
Actress Lizzy Caplan is 26.
Rhythm-and-blues singer Fantasia ("American Idol") is 24.
Thought for Today:
"Many a man thinks he is patient when, in reality, he is indifferent." —
B.C. Forbes, Scottish journalist
(1880-1954).
« Last Edit: July 01, 2008, 08:10:48 am by Bianca » Report Spam Logged
HereForNow
Re: June 30, 2008 - Today In History
Not to mention that we are celebrating the forth of July this week, which means that for many of us.
It's a four day work week. Yeah!
Like most monkeys, I enjoy setting off fireworks and I have lots of nice little boom-booms......
Camp, here I come.
Onwithforever@yahoo.com
Gone with the Wind, a Pulitzer Prize-winning American novel by Margaret Mitchell, tells the story
a rebellious Georgia woman named Scarlett O'Hara.
It presents a detailed view of her complex relationships with family and friends and her struggle
to survive in the American South before, during, and after the Civil War.
Many regard the book as having a strong ideological commitment to the cause of the Confederacy.
Gone With the Wind won the Pulitzer Prize in 1937.
Gone With the Wind was the only novel which Margaret Mitchell wrote.
« Last Edit: June 30, 2008, 09:13:55 am by Bianca » Report Spam Logged

redpajama_set_name: RedPajamaCommonCrawl


text:
namespace mojo {
namespace shell {

// ApplicationCatalogStore implementation that takes the ListValue to return
// as store.
class TestCatalogStore : public catalog::Store {
 public:
  explicit TestCatalogStore(scoped_ptr<base::ListValue> store);
  ~TestCatalogStore() override;

  bool get_store_called() const { return get_store_called_; }

  // ApplicationCatalogStore:
  const base::ListValue* GetStore() override;
  void UpdateStore(scoped_ptr<base::ListValue> store) override;

 private:
  bool get_store_called_ = false;
  scoped_ptr<base::ListValue> store_;

  DISALLOW_COPY_AND_ASSIGN(TestCatalogStore);
};

// Returns a dictionary for an app with the specified name, display name and a
// permissive filter.
scoped_ptr<base::DictionaryValue> BuildPermissiveSerializedAppInfo(
    const std::string& name,
    const std::string& display_name);

}  // namespace shell
}  // namespace mojo

#endif  // MOJO_SHELL_BACKGROUND_TESTS_TEST_CATALOG_STORE_H_

redpajama_set_name: RedPajamaGithub


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Home » Picks » NFL Week 1 2016 – Sunday Game by Game Betting Breakdown – Previews and Predictions
NFL Week 1 2016 – Sunday Game by Game Betting Breakdown – Previews and Predictions
Joseph Falchetti
Week 1 is finally here. The NFL's first Sunday slate of games kicks off Sept. 11th, 2016. In this article, I will preview each game and offer a prediction against the spread or pick on the total, and sometimes both. The goal is to find the most value in each game.
I will start off by saying that I'm not betting every game that I go over in this article. It's likely I will only be betting 5-6 of these games. There are some bets that I like more than others (which I will mention), but by no means am I advocating that you use bet every pick listed in this article.
Handicap the games yourself and if your conclusions line up with mine, then perhaps consider placing a wager. The betting odds we will use for this article are will be from BetOnline (Full Review). They are offering a 50% Deposit Bonus Up to $2,5000 for new accounts on their first deposit.
The prices in this article are not live. The odds listed in this article were accurate when the post was published. Even if you already have an account at BetOnline, make sure to line shop for the best price before placing a wager.
Tampa Bay Buccaneers +2.5 (-110) at Atlanta Falcons -2.5 (-110) Total: 47.5
Tampa Bay and Atlanta are one of the three divisional game in Week 1. Both teams are coming off disappointing seasons. For the most part, this division has been dominated by the Panthers and Saints for the last half decade.
The Falcons started last year winning six of seven games before the wheels came off the tracks in the second half of the season. They won just two of their remaining games and finished the season 8-8.
However, Atlanta seems considerably more talented than then Buccaneers, which fielded one of the worst defenses in the league last season. They finished last year at 6-10, and while they have a young and talented roster, they're probably at least a year away from competing.
Falcons' wide receiver Julio Jones tweaked his ankle earlier this week but did practice in fully on Thursday. He's owned the Buccaneers over the years, and although, he will have to face off against rookie Vernon Hargreaves III – who has stood out in preseason action – this should be an easy matchup for Jones.
One of the biggest issues Atlanta had last year was inconsistent play from the center position and injuries to their offensive line. Their line is healthy, and they upgrade at center, signing veteran Alex Mack.
I lean Atlanta in this game, but I think the best play might be the total. Neither of these teams plays particularly fast (although, Tampa has stated they want to increase the tempo this year), and divisional contests are often harder fought than other games. Both of these teams can and will go to the ground if they can, and both teams have suspect front sevens.
Pick: Under 47.5 (-110)
Minnesota Vikings -2.5 (-115) at Tennessee Titans +2.5 (-105) Total: 40.5
As of right now, the Vikings and Titans have the lowest total of the week at 40.5 points. Minnesota originally opened as -3 favorites. Their starting quarterback, Teddy Bridgewater, had a gruesome non-contact injury in practice.
The Vikings were set to start Shaun Hill, but they then acquired Sam Bradford from Philadelphia in a trade. As of now, Mike Zimmer has not announced a starter for the game and won't do so until Sunday.
Speculation is that Bradford will be named the starter, and Titans' coach Mike Mularkey isn't buying the talk that Shaun Hill will make the start Sunday. Whichever quarterback starts for the Vikings will be at a disadvantage.
Shaun Hill can talk all he wants about how prepared he is to play, but he's a 36-year-old journeyman who didn't expect to play until last week. Bradford isn't a good quarterback, and his role isn't going to change much compared to Philadelphia. Both guys will be handing the ball off to Adrian Peterson.
Tennessee boasts a weak defense, but an excellent coordinator in Dick Lebeau who has had two weeks to scheme up a plan to stop Shaun Hill or Sam Bradford. That plan should work provided they can move the ball on the ground.
Mike Zimmer's defenses have been excellent in recent years, but considerably weaker on the ground. The matchup is a poor one for Titans' quarterback Marcus Mariota if we go by last year's numbers.
However, Mariota improved rapidly as the season progressed last year and Mularkey has a playbook that emphasizes both his arm and legs. He also has talent around him in wide receiver Rishard Matthews and rookie Tajae Sharpe, who had an excellent preseason. Of course, at tight end, there is the reliable Delanie Walker.
The Titans will be one of my favorite plays if the odds move to +3 or better before kickoff, which is where the game opened. The over also might deserve some consideration if you think that the Tennessee's skill players are being undervalued.
Pick: Titans +2.5 (-105)
Cleveland Browns +3.5 (-115) at Philadelphia Eagles -3.5 (-105) Total: 41
The Eagles originally opened at -7 favorites, but after trading away Sam Bradford and opting to go with rookie Carson Wentz, they are now favored by just over a field goal. The Browns are in full rebuild mode but still have some talented pieces, particularly on the offensive side of the ball.
However, Philadelphia shouldn't have much trouble dispatching the Browns. Due to their disappointment over the last few seasons, many people don't have much faith in the Eagles, and we can't blame them.
They deserve a bit more credit for their work in the offseason. Jim Schwartz was hired as defensive coordinator and revamped their secondary. The front seven has looked fantastic as well. They upgraded the offensive as well.
Browns quarterback Robert Griffin III had plenty of highlight reels in the preseason, but he still looked terribly uncomfortable in the pocket and took a lot of sacks. Philadelphia's pressure should force him into some bad decisions.
Wentz is certainly a downgrade from Bradford, at least for now. However, Philly can win this game with their strong running game and their defense. It sounds clichéd to say that "games are decided in the trenches", but that should be how this one plays out. The Eagles are far better on both sides of the ball when it comes to winning the battle up front.
Ideally, it would be great to get this one at -3, but that's probably not going to happen. Even so, Philadelphia should be able to lock this one up by a touchdown or more.
Pick: Eagles -3.5
Oakland Raiders +1.5 (-110) at New Orleans Saints -1.5 (-110) Total: 52
Oakland heads to the Big Easy in a game that sports the highest total of the week. The odds on this one have moved around quite a bit. New Orleans opened as -2 favorites, the game went to pick, and now the Saints are -1.5 at most operators. The total opened at 50.5 and is now at 52.
The Saints are always a force at home, but this is a spot where the Raiders should have an edge. New Orleans has looked horrible in pass protection throughout the preseason, and Oakland's defense has gotten better this offseason. They also have one of the best pass rushers in the entire league, in linebacker Khalil Mack.
Defensively, the Saints are an absolute disaster. Oakland should have no issues scoring against a defense with easily the worst front seven in the league. It doesn't get much better in the secondary either.
The majority of the bets are coming in on New Orleans now, and I expect that to continue into the weekend. It's possible the Saints move closer to 3 points as we get closer to kickoff. Oakland is one of my favorite plays of the week.
I truly believe New Orleans will struggle to score points against their tough defense. The Raiders won't run up the score either, making the under a bet to consider as well.
Pick: Raiders +1.5 (-110)
Cincinnati Bengals -2.5 (-110) at New York Jets +2.5 (-110) Total: 41.5
Cincinnati heads to Meadowlands to take on the Jets in a game that has the second lowest total of the week. The Bengals originally opened as -1 favorites but that has swelled to -2.5. It may also be at -3 at some shops.
We're probably looking at another "grind it out" affair between these two teams, but it should be noted that both teams do have excellent run defenses. To win this game, ultimately, it may come down to the air.
That's an area where the Jets have a distinct advantage in my eyes. Last year, the Bengals finished near the top of the league in pass defense. However, they lost Reggie Nelson and Leon Hall to free agency and are without Vontaze Burfict for the first three games of the season.
Jets quarterback Ryan Fitzpatrick may have to dust some rust off from signing late and this is the spot to do it. Brandon Marshall and Eric Decker both have plus matchups on the outside and in the slot, respectively. They should have no issue dominating.
The public loves the Bengals in this one, but the market has gone the other way. Try to get this one at +3 if you can. It is likely to be available closer to game time. New York is one of my favorite bets this weekend.
Pick: Jets +2.5 (-110)
San Diego Chargers +6.5 (-115) at Kansas City Chiefs -6.5 (-105) Total: 44.5
The AFC West divisional contests kick off with the Chargers visiting Arrowhead Stadium. The spread in this one has hovered around 6.5 and 7 points. San Diego has been terrible against the Chiefs in recent years, but KC doesn't have the defensive unit they did last season.
Their top pass rusher, Justin Houston is on the physically unable to perform list (PUP). Tamba Hali is not entirely healthy and may be on a snap count. Cornerback Sean Smith left for Oakland in free agency.
San Diego's issue is their inability to run the ball or stop the run. It makes it a lot harder to score points when your opponent can run the ball down your throat. However, Rivers often starts the season hot, and this is not KC's vaunted defense that we saw last season, at least, not on paper.
Of course, the Chargers almost certainly won't be able to stop the Chiefs, but this one should stay somewhat close. Rivers' upgraded his weapons in the offseason as well and should be able to put up some points.
I might like the Chargers more as we get closer to Sunday, but for now, I'm just lukewarm on them. If you can get an excellent price on +7 or better, then it may be worth a bet. The best play in his game is probably the total, which seems entirely too small for San Diego's weak defense and Kansas City's unit not being fully healthy and losing a lot in the offseason.
Pick: Over 44.5 (-110)
Buffalo Bills +3 (+105) at Baltimore Ravens -3 (-125) Total: 44.5
Tyrod Taylor returns with the Bills to Baltimore to take on the guy who he sat behind on the bench for several years, Joe Flacco. Now entrenched in a starting role for Buffalo and coming off a new contract, he may view this contest as a revenge game.
I will preface by saying this is probably my least favorite game on this slate and the hardest to call in my mind. These teams are extremely closely matched, and as the oddsmakers have it, it may come down to a field goal either way.
Both teams prefer ball control, run-oriented offenses, which may keep the scoring down. However, the Ravens have thrown a lot more since hiring Marc Trestman. Part of that may be their offensive line or defensive woes, but that's also Trestman's philosophy on offense.
There's a myth going around among fans and bettors alike that the Ravens still have a stout defense. That could be argued that against the run they do, but they did lose personnel up front in the offseason. When it comes to pass defense, Baltimore had some of the worst numbers in the league last season.
The Ravens are also beat up on offense. Nearly half a dozen players have missed training camp or parts of the preseason. They may be better late in the season as they gain continuity and get healthier, but for now, Buffalo is probably the better team.
Pick: Bills +3 (+105)
Chicago Bears +6 (-110) at Houston Texans -6 (-110) Total: 44
Few people are expecting much of game from the Bears this week as they head to Houston. The spread originally opened at -3 and has moved to -6. The public has been all over the Texans, but sharp action was the major reason for the drastic move.
On paper, this looks like a rough one for Chicago. They have all sorts of question marks in the secondary, including injuries. The matchup is extremely tough for Jay Cutler, who has few true weapons aside from wide receiver Alshon Jeffery.
With that said, the Bears have improved drastically in run defense in the offseason. They should be able to get after the passer. The Texans signed Brock Osweiler in the offseason, and if he has a few hiccups under the new system, this game could be a lot closer than expected.
This contest is another one that is I'm not particularly high on either side. Though, that could change if Chicago gets to +7. I would probably favor taking them at that price. It might be possible with the public hammering Houston.
Pick: Bears +6
Green Bay Packers -4.5 (-115) at Jacksonville Jaguars +4.5 (-115) Total: 48
A few years ago, most bettors would expect to see the Packers favored by double digits against the Jaguars, even when facing them on the road. Jacksonville has improved a lot recently, but are they ready to take the next step?
The Jaguars improved their defense last season, particularly in their secondary. Their first round pick was cornerback Jalen Ramsey, who by all accounts has been fantastic throughout training camp and the preseason.
However, their revamped secondary may take some time to flourish. Aaron Rodgers is coming to town this Sunday, and that will be one heck of a test. I'm betting on Rodgers to win that battle.
There are issues for the Jaguars on offense as well. Yes, they're a talent bunch, but Green Bay's defense is a superb unit. Blake Bortles benefits massively from his supporting cast and did have a good year last season, but he's been extremely turnover prone throughout his career.
This one may end up being close, but it wouldn't shock me if Green Bay won by a touchdown or more either. Many people have Jacksonville taking the next step this season, but I think they overachieved last year and are due for regression.
Pick: Green Bay -4.5 (-115)
Miami Dolphins +10 (-110) at Seattle Seahawks -10 (-110) Total: 44.5
The Seahawks are the only team favored by double digits this week. They take on a Dolphins team that is reeling from injuries on both sides of the ball. They're almost assuredly going to lose Sunday, but from a betting perspective, we just care about which team covers.
How bad is it for Miami? Well, without Mike Pouncey at center due to injury, the Fins will start a tackle at left guard and a guard at center. Their secondary is also low on talent and decimated with injury. Miami may also be without second-year receiver Devante Parker due to injury.
Seattle has problems of their own. Their offensive line has long been an issue, but the Seahawks always seem to win in spite of it. Miami's front is something to fear, but we can't see Seattle getting beat up in the trenches.
This is a tough one to call. If you can grab Miami at +10.5 for a decent price, which may be available, come Sunday, go for it. We're going to stick with the Miami at +10 because they still have a decent front seven and their best receiver, Jarvis Landry, operates in the slot where the Seahawks are weakest.
Pick: Dolphins +10 (-110)
New York Giants +1 (-110) at Dallas Cowboys -1 (-110) Total: 46
The spread and total for this NFC East game have changed drastically since opening. Dallas opened as -3.5 favorites with Tony Romo under center. He suffered broken bones in his back once again and is going to be out until at least midseason. The total opened at 49 now points and is now down to 46.
Dak Prescott, a rookie from Mississippi State, will take the reins. Prescott shined in the preseason as both a passer and runner, and he scored over 40 rushing touchdowns in his college career. The Cowboys also boast the best offensive line in the league and have a dynamic rookie running back in Ezekiel Elliot.
The Giants aren't pushovers, and Dallas' defense is definitely not something to write home about. New York addressed their defensive issues last season through free agency, but it remains to be seen how well they perform this year.
The Cowboys are one of my favorite plays this week for several reasons. For one, the public is all over the Giants. Secondly, Dak looks excellent and may even be an upgrade over Tony Romo. Yes, I said it.
Pick: Cowboys -1 (-110)
Detroit Lions +3 (-105) at Indianapolis Colts -3 (-115) Total: 51
As of now, the Colts and the Lions have the second highest total at 51 points. Indianapolis opened the game as -5 favorites, but that has come down to three points after heavy sharp betting action. The public is still heavily betting the Colts.
Stafford and the now up-tempo Lions have a mouthwatering matchup against a Colts defense that isn't equipped to rush the passer or cover in the secondary. Vontae Davis, their top cornerback, is out a month. Darius Butler, their slot cornerback, has also been ruled out.
Colts quarterback Andrew Luck is coming off a fat contract extension and is finally healthy. He has plenty of weapons, but Luck needs to be a better quarterback in addition to staying healthy. That means cutting down on the turnovers. Indianapolis has all kinds of issues on the offensive line, so it may be hard for Luck and this offense to get going.
After turning their offense over to Jim Bob Cooter last season, the Lions won six out of their last eight games after starting the season with a 1-7 record. Defensively, Indy has the worst unit in league with all their injuries right now.
Detroit might be my favorite overall play in Week 1. I got Detroit at +3.5, and there's a chance it moves back there by kickoff time.
Pick: Lions +3
Check back later for more picks. We will have larger breakdowns of the Sunday Night Football and both Monday Night Football games. Good luck!
Joseph Falchetti - Editor-in-Chief / Sports Writer & Analyst
Joe is the author of the blog, most picks, and the majority of excellent content on SafestBettingSites. He's been mentioned on Forbes.com as a gaming analyst and his articles have been linked by larger publications, such as the New York Times.
Joseph Falchetti Bio
NFL 2016 Kickoff: Carolina Panthers at Denver Broncos – Preview and Prediction
Joseph Falchetti | September 8, 2016
Sunday Night Football Week 1 – New England Patriots at Arizona Cardinals – Preview and Prediction
Joseph Falchetti | September 10, 2016
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text:
Adrenaline for the Soul: The Greenwich Village Orchestra in Concert 11/18/07
It's hard to believe that this world-class orchestra has somehow managed to fly so far below the radar. For a $15 donation, classical music fans can see reliably good, frequently exhilarating performances of both popular and obscure works, discover new composers and watch some of the best up-and-coming talent at the top of their game. Shows as good as this afternoon's spiritually-themed program by the Greenwich Village Orchestra usually cost a hundred dollars or more at the Midtown concert halls. Plainly and simply, there is no better music value in New York.
While the afternoon's theme (this orchestra LOVES theme programs) was spirituality, it would have been better put as a celebration of everything that makes life worth living, a frequently riveting, exuberant, passionate performance. They began slowly with two orchestral arrangements of Bruckner motets, the first a pretty generic, post-baroque melody, the second slightly more interesting but ultimately nothing more than a standard pre-Romantic Northern European piece, nothing Mendelssohn didn't do a hundred times better.
But they brought out every bit of drama in the next piece, Rimsky-Korsakov's Easter Overture. It's a celebration of the Resurrection, opening all quiet and suspenseful but building quickly to a fiery, galloping, gypsyish folk dance in three movements. On the podium, Barbara Yahr spurred the orchestra to play with wild abandon, and they delivered.
In keeping with the spiritual theme, three representatives of New York spiritual communities each delivered a short introduction to a particular piece of music. Rabbi Ayelet S. Cohen of Congregation Beth Simchat Torah impressed the most by quoting influential civil rights crusader Rabbi Abraham Heschel on how prayer is by definition transgressive, that one's spiritual life necessarily works against the status quo in seeking higher ground. It was an apt way to kick off Max Bruch's heart-tugging Kol Nidrei, based on the prayer invoked the night before the Jewish day of atonement, Yom Kippur. Guest soloist Eric Jacobsen played his part on the cello from memory with an intensity that made it look as if he was about to break strings. He's a rising star, and for good reason, with a seemingly effortless vibrato and a sense of dynamics that doesn't stop at fortissimo. His blazing interpretation burned away any trace of sentimentality that could have insinuated itself into this highly emotional composition.
The following work was a world premiere, young Hong Kong-born Angel Lam's Her Thousand Year Dance. If this piece is typical of her other material, it instantly establishes her as a first-rate composer, blending the windswept, pastoral beauty of traditional Chinese classical music with western tonalities. Beginning abruptly with a few bursts from special guest Kojiro Umezaki's shakuhachi (an oversize Japanese wood flute), it rose to an ethereal, atmospheric yet rhythmically difficult altitude and pretty much stayed there for the duration, aside from a couple of breaks with light percussion. That the afternoon's final piece, Richard Strauss' Death and Transfiguration, would be anticlimactic speaks volumes about what preceded it. Yahr led the ensemble through a highly idiosyncratic yet extremely successful reading. Although there are no breaks written in the music, Strauss wrote this ultimately triumphant chronicle of struggle and redemption in four distinct parts. While the piece is frequently played with an emphasis on overall ambience, Yahr spelled out the dynamics in capital letters, putting teeth in both the ebbs and swells, an unexpected thrill ride to close what had to be the most exciting classical bill anywhere in town this week.
The media typically holds classical musicians to a higher standard than rock or jazz players (which is grossly unfair: everybody, even the greatest virtuosos, make mistakes). If there were any technical flaws in this afternoon's performance, it would be the sluggishness of the horns early on in the Bruckner and some general weirdness (tuning issues?) in the violins early during the Lam. Otherwise, Yahr steered this careening unit directly into high winds and stormy seas and then brought everyone back into port unscathed, the crowd (on the docks, if you want to bring the metaphor full circle) all on their feet, roaring their approval. The GVO's next concert is December 16, billed as a kid-friendly show featuring Saint-Saens' witty, interesting, multi-part Carnival of the Animals (which gets pegged as a children's piece even though it's quite sophisticated), along with pieces by Mozart and Mendelssohn.The GVO's best deal is their series subscription, especially considering what lies in store: in addition to the December 16, the remainder of the season features works by Shostakovich, Bach, Brahms and others. The concerts continue to be held at Washington Irving High School auditorium as they've been for several years, considering the room's excellent sonics (it seems to date from the 19th century and at one time even housed a concert organ, whose pipes still stand to the left and right of the stage).
November 19, 2007 Posted by delarue | classical music, concert, Live Events, Music, music, concert, New York City, review, Reviews	| angel lam, asian classical music, asian music, avant-garde music, ayelet cohen, ayelet s. cohen, barbara yahr, beth simchat torah, bruckner, cheap classical concert new york, cheap classical concert nyc, classical music, death and transfiguration, eric jacobsen cello, greenwich village orchestra, kojiro umezaki, max bruch, max bruch kol nidre, new music, new york orchestra, orchestral music, rabbi abraham heschel, richard strauss, rimsky-korsakov, rimsky-korsakov easter overture, romantic music, shakuhachi music, strauss death and transfiguration, world music | 1 Comment
Concert Review: Demolition String Band CD Release Show at Rodeo Bar, NYC 11/16/07
If you want to buy something substantial, say, a car or a guitar, you want to take it for a spin. You want to hear what it sounds like. Likewise, it makes no sense to buy a cd sight unseen: no matter who's putting it out, you need to know if it's worth it. One surefire way is to hear the songs live: anybody can fix mistakes in the studio, overdub guitars or vocals til the cows come home, but how do the songs stand up without any added embellishments? If this show is any indication, Demolition String Band's new one Different Kinds of Love completely and totally kicks ass.
X would be the closest comparison for this band. Although Demolition String Band aren't punk by any stretch, they share the legendary LA band's love for both American roots music and sheer guitar volume. In an age where rock has actually taken over country radio, this album is particularly well-timed. Tonight they mixed up a bunch of catchy, twangy country tunes with a couple of blazing straight-up rock songs and some dazzlingly played bluegrass.
They opened on the rock tip with Hurt So Bad, featuring a Stonesy Keith Richards-esque intro from Telecaster master Boo Reiners and followed that with the best song of the night. Written by frontwoman Elena Skye – who's been on something of a tear lately coming up with new material – it rocked all the way through its ominous minor-key intro until they reprised it at the end. Then they invited their friend Rina (Did we spell it right?) to sub the backing vocal part that Mary from Southern Culture on the Skids did on the recorded version of the pretty, traditional country tune I Wanna Wear White.
The band blazed through their reliably crowd-pleasing cover of Madonna's Like a Prayer – "See, Madonna can write a great country song, she just doesn't know it," Skye told the audience – and then returned to their originals with a fast, backbeat-driven song inspired by Skye's daughter, and then the twangy, midtempo Baby Won't You Come Home on which Skye switched to mandolin. Reiners took over lead vocals on another relatively new Skye song, the fast, electric bluegrass number Thinking About Drinking, then thry brought it down again with a slow ballad on which Reiners played his heart out with a long solo.
Their cover of the Ola Belle Reed classic Where the Wild Wild Flowers Grow rocked hard, crescendoing with a bluesy 70s rock guitar solo. On the tune after that, Reiners left his wah-wah pedal (or was it a flange?) wide open during another long solo, letting his tone phase in and out and the way he made the melody work with it was as impressive as it was amusing. After a fast bluegrass instrumental followed by their excellent new song Drinking Whiskey (a tribute to bootleggers, it seems, carefully explaining how "you got your selling, and your drinking whiskey") they closed their long, exuberant first set with the old bluegrass standard True Love Never Dies. As if to check to see how hard the crowd was listening, Reiners threw in several sly Beatles quotes, then they sped it up almost doublespeed, finally wrapping it up as he played the big hook from Hendrix' Little Wing. Party music doesn't get much more clever or entertaining than this. Lookout Nashville, here they come. CDs are currently available online for pre-order or at shows (Demolition String Band usually play Rodeo Bar at least once a month when they're not on the road playing with SCOTS or some other good country touring band).
November 19, 2007 Posted by delarue | concert, country music, Live Events, Music, music, concert, New York City, review, Reviews, rock music	| americana music, americana rock, best bands new york, best bands nyc, best guitarist nyc, bluegrass, bluegrass guitar, bluegrass music, boo reiners, country guitar, country music, country rock, demolition string band, elena skye, hillbilly music, like a prayer country version, madonna cover, madonna like a prayer country, ola belle reed, Southern Culture on the Skids, twang rock, x band | 3 Comments
Concert Review: Erin Regan and Randi Russo at Sidewalk, NYC 11/17/07
As if we need more proof of how New York has gone to hell, a girl playing onstage early here tonight did a pro-gentrification song. It used to go without saying that at least you could count on the music community here to stand up against the destruction of working-class and minority neighborhoods. Not anymore. Maybe the girl likes having a Starbucks on every corner, or she can't wait to push that Humvee stroller straight down the middle of the sidewalk, scattering less fortunate people left and right. Or maybe her song was a thank-you card to mom for buying her that $3 million condo in Park Slope.
As inauspiciously as the night began, Erin Regan turned everything around in a matter of seconds. If you saw Ghost World and instantly wanted the Thora Burch character for your best friend, Regan is for you. She doesn't do the movie's almost over-the-top personification of clinical depression – she actually smiled and joked a little with the audience. But her songs would do Enid proud. Regan's vocal delivery is deadpan and sullen, with an icy dismissiveness. Whatever wounds she's sustained still seem fresh (probably a simple case of having grown up as a cool kid surrounded by morons – it's a common injury, but it can take years before it's safe to look back and just laugh). Her stage persona may say stay the hell away from me, but her bleak, outsider chronicles are welcoming and inclusive, and will resonate hard with any other cool kids who've been liberated (or long to be liberated) from a stifling environment. She made a great segue with Randi Russo. Her best number was a snide, bitter look back at a wasted youth spent bumming cigarettes from older kids and stealing things: if only things were simple then, she mused sarcastically. But they're not. It might have been just Regan and her acoustic guitar onstage tonight, but she packed a wallop. Add her to your must-see list.
Russo and her band are too loud and too popular for a room this size. Credit Somer the soundwoman for keeping their sonic onslaught at a listenable level. Since returning from her solo European tour this past summer, she's been working the band out a lot more than she was earlier this year and they've benefited from it, two blazing electric guitars (Russo being one of them) and a pummeling rhythm section who have really pulled it together. Nobody writes a more potent outsider anthem than Russo, and tonight she and her supporting cast played a bunch of them. After opening with the stomping, Velvets-esque One Track Mind ("Stay true to the one," she admonished the audience: don't sell out, don't let the bastards wear you down), she led the band through the pretty, backbeat-driven escape ballad Get Me Over, the fiery, slightly funky workday alienation number Battle on the Periphery, the towering, sarcastic epic Wonderland (which has become something of a signature song for her) and the stomping That Corpse, which sounds completely macabre until you listen closely and then it's obvious that it's a joke, like something the Cramps would do. The high point of the set was new one, a 3-section partita that begins with a relentless, driving drum and bassline, eventually morphing into a blistering, guitar-fueled outro where the bass eventually picks up on a recurrent Middle Eastern riff. "Keep your head high while you lie low," Russo intoned over the maelstrom. They closed with the uncharacteristically sunny, optimistic, ambient Ceiling Fire, with lead guitarist Lenny Molotov playing gorgeous, Byrds-like jangle melody on the choruses. The sound woman then took over the stage, playing solo through a big amp. From what we could tell, she had good energy, but the place was clearing out and we had places to go and things to do.
November 19, 2007 Posted by delarue | concert, Live Events, Music, music, concert, New York City, review, Reviews, rock music	| acoustic music, acoustic rock, best bands new york, best bands nyc, best singer new york, best singer nyc, best songwriter new york, best songwriter nyc, erin regan, folk music, indie rock, noir music, noir rock, psychedelia, psychedelic music, psychedelic rock, randi russo, rock music, singer-songwriter, songwriter | 4 Comments


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Terms and Conditions for End Users
ReceiptHero Oy has developed an open ReceiptHero ecosystem for receipts that enables the transmission of electronic receipts ("ReceiptHero").
ReceiptHero can be utilised by merchants who produce receipts ("Merchants"), application developers who process receipts ("Application Developers"), in relation to their applications ("Partner Applications"), business customers along with their representatives ("Business Customers"), as well as consumers who have reached the age of majority ("Consumers", Business Customers and Consumers jointly referred to as "End Users" hereinafter).
These terms and conditions define the terms in accordance with which End Users may utilise ReceiptHero.
ReceiptHero transmits electronic receipts and thereto related personal data related between different actors. With ReceiptHero, End Users will receive electronic receipts for their purchases with Merchants. Additionally, End Users may activate ReceiptHero in connection with Partner Applications, and thereby receive from Application Developers services based on electronic receipts.
ReceiptHero can add to the electronic receipts marketing messages from Merchants or Application Developers, or perform other marketing on behalf of the Merchants or Application Developers. ReceiptHero can also compile from the electronic receipts anonymous statistical reports and disclose such reports to Merchants in accordance with the Privacy Notice of ReceiptHero.
End Users use ReceiptHero at their own risk. The use of ReceiptHero is free of charge, but the services offered by Application Developers may entail separate fees.
In order to use ReceiptHero, each End User is required to accept these terms and conditions as well as the Privacy Notice available on ReceiptHero's website. These documents will form the entire agreement concerning the use of ReceiptHero between ReceiptHero and the End User ("Agreement").
The Agreement is concluded when the End User has accepted these terms and conditions and ReceiptHero's Privacy Notice, or, at the latest when the End User has commenced using ReceiptHero. An agreement between a Business Customer and ReceiptHero may also include other appendices and may require that a valid employment relationship exists between the Business Customer and the representative of the Business Customer.
In case of conflicts between the agreement documents, ReceiptHero's Privacy Notice (as well as the agreement between ReceiptHero and the Business Customer) will take precedence over these terms and conditions.
The potential agreements concluded by the End User with the Application Developers or Merchants are not a part of the Agreement.
4. Activating ReceiptHero and Partner Applications
ReceiptHero is activated though registration at ReceiptHero's online service for End Users or in connection with a Partner Application.
In connection with the registration, the End User gives his/her contact details as well as his/her personal identifiers used in connection with the transactions, such as payment card information or email address ("ReceiptHero Identifier"). The End User can use the ReceiptHero Identifier to activate ReceiptHero in connection with new Partner Applications.
The End User is responsible for the information they have provided and that the End User has obtained the necessary authorisations to utilise the provided identification information. Using a third party's identification information without authorisation is strictly prohibited and may lead to criminal liability.
ReceiptHero has the right to disable such ReceiptHero Identifiers it suspects are misused or whose user is no longer employed by the Business Customer in question.
5. Provision, Transmission and Inspection of ReceiptHero Receipts
An electronic receipt transmitted by ReceiptHero ("ReceiptHero Receipt") contains such basic information that is also included in a regular receipt, such as the seller's contact details, the purchased items or services and the price of the purchase including taxes, date of the issuing of the receipt and the identifier of the receipt.
ReceiptHero Receipts are offered by Merchants who utilise ReceiptHero. In order to receive a ReceiptHero Receipt, a ReceiptHero Identifier must be used in connection with the transaction. A ReceiptHero Receipt is produced in connection with the transaction based on the ReceiptHero Identifier in question. Thereafter, a ReceiptHero Receipt is transmitted onwards to the End User in the manner described in more detail in the ReceiptHero Privacy Notice. Since the Merchants are entitled to prohibit the transmission of ReceiptHero Receipts to certain Partner Applications, it is possible that certain ReceiptHero Receipts are not available or usable in all Partner Applications.
ReceiptHero Receipts can be inspected at ReceiptHero's online service and in certain Partner Applications. Also, if so requested by the End User, the ReceiptHero Receipts are forwarded to the End User's personal communication tools (such as email address or Facebook Messenger application). The forwarding times, views, and archiving times of ReceiptHero Receipts may vary between applications.
6. Application Developer's Services and Partner Applications
In connection with the Partner Applications, the Application Developers may offer to End Users receipt inspection and viewing services and other services based on ReceiptHero Receipts. The services provided by Application Developers to End Users may be subject to a fee and may require a separate agreement with the Application Developer. The details of the services provided by Application Developers are defined in the agreement between the End User and the Application Developer.
7. ReceiptHero's Maintenance and Defects
ReceiptHero makes reasonable efforts to ensure that ReceiptHero is available 24 hours per day every day of the year, excluding the development and service windows of which ReceiptHero endeavours to communicate well in advance.
In case of fault-related queries such as questions concerning delayed or missing ReceiptHero Receipts, the End User may contact ReceiptHero directly. If the fault concerns a Partner Application or only appears in connection with a Partner Application, or relates to the services of an Application Developer, the End User must contact directly the Application Developer in question.
ReceiptHero may develop and modify ReceiptHero. ReceiptHero has the right to modify these terms and conditions as well as the ReceiptHero's Privacy Notice by notifying the End User at least 90 days in advance. If the End User uses ReceiptHero thereafter, such use is considered to be an acceptance by the End User of the updated terms and conditions or Privacy Notice.
9. Charges and Expenses
ReceiptHero is provided free of charge to End Users. The End User is responsible for any expenses resulting from the use of ReceiptHero, such as expenses relating to the devices, software or network connections required by ReceiptHero. The End User is also responsible for possible charges relating to the services offered by Partner Applications.
ReceiptHero complies with personal data legislation in force in Finland as well as the Privacy Notice available on ReceiptHero's website, which the End User confirms to have carefully familiarised himself/herself with.
11. Data Security
ReceiptHero enforces customary data security policies, such as the encryption of transmitted data and limited backups. ReceiptHero has the right to temporarily disable access to ReceiptHero, if (i) the End User, or the devices or software used by the End User, potentially endanger the data security of ReceiptHero or third parties, or if (ii) a serious information security threat is directed at ReceiptHero.
ReceiptHero or its licensors own all intellectual property rights to ReceiptHero (including copyright, databases, trademarks, design rights, patents, utility models, domain names and the applications for such).
End User can utilise ReceiptHero only in accordance with the Agreement and for the term of the Agreement. End User acknowledges and agrees that ReceiptHero and its background software contain business secrets of ReceiptHero and third parties, such as the source code of the software, specific design of the software components, constitutional formula and logics, programming techniques and related documents. Copying, dismantling, inspecting or reverse engineering of ReceiptHero or its background software is prohibited.
If a third party claims that ReceiptHero infringes its intellectual property rights, ReceiptHero has the right (i) to acquire the necessary licences in order to continue the provision of ReceiptHero, (ii) modify ReceiptHero in order to eliminate the infringement or (iii) terminate the Agreement with immediate effect. In such situations, ReceiptHero has no other liability or obligation.
13. No Warranties, Limitations of Liability
The utilisation of ReceiptHero is at the End User's own risk. To the extent permitted by mandatory law, ReceiptHero is offered "as is" without any warranties regarding its availability, usability, accuracy or applicability to certain purposes. ReceiptHero is not liable for direct or indirect damages, such as loss of data or its recreation, loss of profit or interest, decrease of revenue, harm to reputation, cover purchases, third party injuries or other unforeseeable damages, nor is it liable for the services provided by Partner Applications or the products or services purchased from Merchants.
14. Term of the Agreement
The Agreement is in force until further notice or, in regard to a Business Customer, for a fixed term specified in the Agreement. The Consumer has the right to cancel the Agreement within 14 days of concluding the Agreement or activating ReceiptHero by notifying ReceiptHero in writing.
End User has a right to terminate the Agreement for convenience at any time without a notice period by informing ReceiptHero in writing. ReceiptHero and Business Customer have a right to terminate a non-fixed-term Agreement for convenience by complying with a 60-day notice period. The terms of the Agreement shall be complied with during the notice period.
Both parties also have the right to terminate the Agreement for cause with immediate effect, if (i) the other party has materially breached the Agreement and it has not corrected its behaviour within 14 days after receiving the other party's written notification of a contract breach, or if (ii) Business Customer or ReceiptHero go bankrupt, are placed in corporate debt reorganisation or otherwise become unable to meet their responsibilities under the Agreement.
After the Agreement has ended, the End User's ReceiptHero Receipts and other personal data will be destroyed in accordance with ReceiptHero's Privacy Notice, unless compelling legislation provide otherwise.
A party is not responsible for delay or damage that is due to an obstacle outside of the influence of a party, which a party cannot reasonably have been expected to take into consideration at the time of entering into the Agreement, and the consequences of which the party could not reasonably prevent or overcome, and due to which the fulfilling of the party's obligations or responsibilities becomes unreasonably difficult or impossible ("Force majeure"). A Force majeure is, for example, war, demonstration, labour dispute, strike, industrial action, fire, natural disaster, communications disruption or other similar event. A party has a right to terminate this Agreement with immediate effect, if Force majeure has had an impact or will have an impact to the fulfilment of the Agreement for at least 30 days.
16. Other Terms
Applicable law and dispute resolution. Laws of Finland shall be applied to the Agreement. Disputes arising from or in connection with the Agreement will be first and foremost solved through negotiations between the parties. If, within 60 days, the negotiations do not result in a satisfactory outcome to the Parties, disputes shall be resolved in the District Court of Pirkanmaa as a first instance. A Consumer, however, has always the right to submit a matter related to the Agreement to the Finnish Consumer Disputes Board.
Transfer of the Agreement, subcontracting. ReceiptHero and Business Customer have a right to assign the Agreement, in whole or in part, to a third party to whom the business activities described in the Agreement are transferred to, or to a company belonging in the same group of companies. ReceiptHero has a right to use subcontractors in fulfilling this Agreement. ReceiptHero is responsible for the actions of its subcontractors like it is for its own.
Partial invalidity. If any provision of this Agreement is later found to be void or invalid by a final judgment of a competent court of law or by another authority, such invalidity or will not invalidate the entire Agreement, but the Agreement remains in force in all other respects.
Terms and Conditions for Merchants
Terms and Conditions for Application Developers


Three people were robbed at gunpoint in a matter of a few hours last week.
It's unclear whether they're related, but they all took place within a few miles of each other between midnight and 1:45 a.m. Friday, Dec. 9. That's in addition to the four armed robberies (two of which were in Oak Cliff and West Dallas) committed by three bandits early Saturday.
The Dallas Morning News reports that two people held up the Walgreens at Colorado and Beckley around midnight Friday.
Two people in a gray SUV robbed a woman at gunpoint near Britton and Illinois around 1 a.m.
And then three people kicked in the back door of a house in the 700 block of Melba brandishing weapons and demanding money.
Thank you so much Rachel for your assistance! I'll let my neighbors know as well.
Christine, I put a call into Oncor to see if they can give us an update. Sorry to hear that!
We still do not have our street lights on Beckley between Zang and Colorado. We were told by the City of Dallas the lights were to be installed the week of 11/14/16 by Oncor. This is not helping deter the crime in this area.


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North Transept
Two shrines – dedicated to the Sacred Heart of Jesus and the Virgin and Child are – contain features from nature that are full of symbolism.
The Virgin and Child Shrine (left) has images of white lilies and roses on its pedestal, signifying purity, virginity and rebirth. The lily also appears as the stylised Fleur de Lis, made up of three lily petals, in the tiling in front of the shrine..
The Sacred Heart Shrine, meanwhile, incorporates a marble panel with a heart surrounded by the crown of thorns the Roman soldiers thrust onto Jesus' head before his crucifixion. Both are also surrounded by stylised flowers.
Pause also to look at the window in the North Transept, where the third panel shows St Elizabeth of Hungary carrying flowers in her robe.
According to legend, whilst she was taking bread to the poor in secret, Elizabeth met her husband Ludwig on a hunting party.
Some of the gentry believed Elizabeth to be stealing treasure from the castle, so Ludwig – who supported her charitable work – asked her to reveal what was hidden under her cloak.
Instead of the bread, all that could be seen was a vision of white and red roses.
The gentry were satisfied and Ludwig was convinced that God's protecting hand was at work
Elizabeth of Hungary with flowers
BLESSED SACRAMENT CHAPEL
NORTH AISLE
HIDDEN NATURE in ST MARIE's
South Aisle
South Transept
St Joseph Chapel
← Back to Visit Us


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Dalai Lama in Delhi for Buddhist discourses
Indo-Asian News Service, March 21, 2008
New Delhi, India -- The Dalai Lama arrived in New Delhi on Friday evening for a week of Buddhist discourses, hours after a group of Tibetan youth managed to scale the Chinese embassy compound wall in New Delhi to protest Beijing's crackdown in Lhasa.
The Dalai Lama reached New Delhi around 7.30 on Friday evening and will stay at the Ashoka Hotel. "His holiness the Dalai Lama will be in the capital March 22-29 to give a teaching on Buddhist philosophy. This has been planned since last year," Kalsang Yudon, secretary of the Dalai Lama, told IANS.
She added that he has no plans to meet members of the press or issue any statements during his stay. To a query if the Dalai Lama had heard about protesting Tibetan youth entering the Chinese embassy, she said, "I don't know."
The Dalai Lama, who has been living in exile in Dharamsala, Himachal Pradesh, since 1959, will meet Vice-President Hamid Ansari. This was revealed by External Affairs Minister Pranab Mukherjee, who stressed that India has always recognized the Tibetan Autonomous Region as part of China.
"India's one-China policy remains unchanged. There is no review of that," Mukherjee said.
Earlier, the Tibetan spiritual head who favours autonomy for Tibet met US House of Representatives Speaker Nancy Pelosi in Dharamsala, the seat of the Tibetan government-in exile. Pelosi extended her support for the Tibetan cause and called for an international independent inquiry into Chinese allegations that the Dalai Lama was behind the Lhasa riots.
In New Delhi, the Dalai Lama will speak on meditation and chapters of Buddhist philosophy such as wisdom teaching.
"His teachings, which will be held everyday for four hours, will be attended by more than 150 people. All the people had registered themselves last year," Yudon said.
The 73-year-old leader, who won the Nobel Peace Prize in 1989, this week threatened to resign as the head of the Tibetan government-in-exile if the Chinese crackdown on ethnic Tibetan protesters in Lhasa escalated.


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Category : International Startup
Posted On : 21st, September 2017
From the inquisitive dreamer to an established entrepreneur journey of Varun Shoor of Kayako
21st, September 2017 - International Startup
In the present times of ever burgeoning education boom, with the college graduates increasing every year to the figures of multiples of millions, the prospect of a steady income stands on slippery grounds. Finding a stable job has never been harder, and sounds rather nightmarish without any college degree. At a tender age of 16 when most students of his age were busy tackling their 10th boards, Varun Shoor decided to develop software to trade it away as an open source.
The circumstances were not always favourable, ₹75000 of his dad's hard earned money had been wasted for Varun's web designing experimentations. But it seems not all his experimentations were profligatory. There were many websites for Varun to test his latest code, Web Hosting Talk was one among them. At a time when "programming" was not common knowledge and was one of the pastimes where people stared at the screens, Varun taught himself how to code at the age of 13. His experimentations with codes and web designing considered crazy, didn't auger well until he stumbled upon a company that sold customer support software for $2,000. Varun had credible experience in programming as he had been learning FoxPro and Visual FoxPro in his spare time. As inquisitive as Varun was he tried his hands on a piece of software. He completed it within 6 months but as it steered his vital focus away from his studies, his father was not pleased and urged him to discontinue and refused any monetary assistance.
Undeterred, Varun plodded on to hire a domain by the name of Kayako.com. Asked about the name's significance he goes on to reply smilingly "a friend of mine referred me Kayako.com, and the reason is it was free and was expiring in 3 months. The friend who had a hosting company had no use for it. This is all there is to it, it is a random name", said Varun in a voice clothed with honesty. Varun had to practise discretion with his e-commerce management because of his father's explicit disapproval. Luckily his father had incorporated a company in his name and a third party company helped him with his transactions with a minimal fee. Once his payment problem found a solution he had everything at his disposal to start selling his software, but there was a catch, promotion and advertisement were still important requisites to divert traffic to his website. He created 20 different identities on Web Hosting Talk from different IP addresses and helped other users to develop credibility of some form. After countless many word of mouth promotions from multiple accounts he got his first order and a payment of $1000 with it. His parents were quite sceptical about his foray and his earnings but were left quite confused when earnings found its way to his pockets.
His hobbies had morphed into a business, and his passion was now fuelled further by a steady cash flow of ₹40000 per month. With a whole lot of courage Varun's father acquiesced to his conducting of an online precarious business. But the compromise came at the cost of college education. Varun's vested interests asked full commitment and Varun wasn't loath to it to keep his newfound business standing. The business was breathing well, well enough to attract prospective buyers and Varun had to tackle them by projecting an outward semblance of "big business". "If they knew I was a 17 year old kid on the other side of the world, they never would have purchased the product", he fondly remembers. He redirected the calls to "different departments", while he was actually operating the entire business from his home.
Varun continued to expand his business and by 2005, he was able to manage a revenue run rate of $1.5 million. The business was booming now, at a rate that overshot both Varun's expectations and his preparations. Inexperienced in people management skills, the newly opened office imploded miserably as it struggled to conduct its operations. The employees left in droves as Varun tried to contain the disaster. Challenges were galore as Varun had made another crucial mistake, he had underestimated the true size of his market, something that he realized in a trade show he attended in Hanover, Germany. "Many companies that I never heard of were making 10 million", he said and thus his own shortcomings helped him put things into perspective. There was another problem to be solved - dearth in the number of engineers as only 4 engineers shared the workload out of his 60 employees. Varun eventually decided to open a new office in Delhi and hired more engineers to extricate his company from the quagmire it found itself in.
With a cloud based venture, SaaS (software as a service) product to boot, the expansion of business reached a range of 8-12 million (in dollars) in 2013. With 3 out of 8 Ivy League universities using Kayako, it has become a force to be reckoned with and that is without any expenditure on marketing, purely based on word of mouths and search engine rankings. About 50 per cent of incoming clients are from customer referrals. Whatever limited marketing or no marketing at all that Varun uses seems to be working as his company now serves 50000 customers in over 100 companies and that includes Peugeot, De Beers, NASA, and The American Motorcyclist Association.
From the inquisitive dreamer to an established entrepreneur, Varun's journey was one filled with challenges, scepticism and failures. From his home office that was restricted to a chair and his x286 computer to the one he opened in London, his business grew beyond his dreams. What once were his wasteful hobbies are now building blocks of his business. Ranking 12 in the Top 15 CRM Companies to WORK for, it manages revenue of ₹1-5 billion per year as of 2017. Discussing the possible opening of an office in Silicon Valley, Varun who originally hails from Jalandhar shares his mantra "pursue what you wish to, with hard-work".
Website: Kayako.com
Categories: Startup Event , Startup , Startup community , News , Food tech , Legal tech startup , HR Tech , Tech Startup , Guest blog , Featured entrepreneur , Startup funding , FinTech , International news , Analytics , Product review , Social enterprise , Health care , My journey , Co working space , Fashion , Sponsored , F&B
Neelanchal
Neelanchal is a student who is currently pursuing his B.Tech in computer science. His interests are many and diverse and it mirrors his personality. He takes a special liking to creative literary writing and in spite of his technical background devotes substantially to the written word. He is eternally devoted to his pursuit of knowledge.
21st, September 2017


Fuel Games has announced the pre-sale launch of their online game, Gods Unchained. The multiplayer strategy game showcases how blockchain technology can be used to offer gamers absolute, trust-free ownership of the items they purchase or earn in games.
"Gamers spend tens of billions of dollars and countless hours each year acquiring in-game items. But game studios barely offer their users a licensing agreement for these items, let alone actual ownership – they're a central bank with no oversight," according to Fuel Games.
"Offering players true ownership of in-game items, and the ability to trade those items freely on secondary markets, means gamers can finally be rewarded for their efforts and spending," said a company spokesperson.
"Decentralised games will allow people to familiarise themselves with blockchain technology in a fun and user-friendly environment," said a company spokesperson.


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Penrith Panthers 2020 season preview
Alicia Newton NRL Reporter
Sat 29 Feb 2020, 08:01 AM
No one could've predicted the turmoil ahead for the Panthers in 2019 when it was announced Ivan Cleary would return as coach.
A series of off-field incidents followed with general manager Phil Gould's resignation after eight years at the helm, and then came the defection of home-grown stars Dallin Watene-Zelezniak and Reagan Campbell-Gillard to rival clubs.
After two years of finals appearances, the Panthers went through the highs and lows and a mini rebuild along the way, blooding a fresh crop of emerging stars.
The club will be hoping the short-term pain turns to long-term gain despite many writing the squad's chances off before a ball has been kicked.
The arrival of premiership-winning prop Zane Tetevano and Sea Eagles rake Api Koroisau could prove the vital piece to an evolving puzzle.
The 2020 outlook
A hooker – and a creative one at that. Api Koroisau's return to Penrith adds a fresh attacking structure out of dummy half, something they haven't had since James Segeyaro's flash of brilliant form in 2014.
The departure of veteran five-eighth James Maloney leaves a gaping hole in terms of experience and creativity so the Panthers will need to change their attack and utilise Koroisau's services in both departments.
Trent Barrett's arrival as an assintant coach is also expected to benefit emerging halves Jarome Luai and Matt Burton, while Tyrone May should be available for selection in round five.
Tamou confirms captaincy and reacts to captain's challenge
The draw
The Panthers have a difficult start with clashes against the Roosters, Storm and Raiders inside the first five weeks of the competition.
Their season opener with the Tricolours could come at a good time with the defending premiers preparing for life without Cooper Cronk and Latrell Mitchell.
During the representative period, Penrith will host the Knights four days after Origin I, while they'll face another big challenge around Origin III with away trips against the Broncos and Sharks.
Ivan Cleary's men finish the regular season with a friendly five of their last seven games played at home.
The stat that gives you hope
The Panthers used the most players in the competition with 33 at an average age of 24.5 - the second youngest in the competition - while handing NRL debuts to nine players.
That they were able to turn around a difficult off-season plagued with scandal, along with a six-game losing streak, and come out the other side with promise is enough to leave fans knowing the side won't give up regardless of the situation.
The bounce back factor is also on the agenda with the Panthers not missing back-to-back finals series since 2013.
Cleary hopes to put smiles on faces
Ivan Cleary goes into the 2020 season with a far more settled squad after last year's summer of turmoil but the Panthers coach will feel slightly under the pump should his men fail to fire.
Cleary returned to the Panthers with a weight of expectation and is contracted until the end of the 2023 season.
His coaching record sits at 45.1 percent at the foot of the mountains across two stints with one finals series under his belt.
Soward's Say: 2020 Panthers
What you need to know NRL Fantasy-wise
"Nathan Cleary ($785k) is already a Fantasy superstar – he's scored an astronomical 120 points in a single game twice – but the departure of James Maloney could mean even more playmaking duties fall to Cleary this year. Jarome Luai ($249k) looks like a steal as Cleary's new halves partner, and Api Koroisau ($493k) is one of the best bargains of 2019 with a big-minute hooker spot available at Penrith after he played closer to 40 minutes a game at Manly." - Lone Scout
Five key match-ups of the Panthers' 2020 draw
Contract matters
Penrith's management will have a decision to make around starting players James Tamou, Dylan Edwards and Brian To'o, who are all off contract at season's end.
Tamou, 31, has expressed a desire to remain at the club after taking the mantle from James Maloney as the most experienced player in the line-up with 245 NRL appearances.
At the other end of the spectrum, local juniors Caleb Aekins, Dean Blore, Shawn Blore, Jed Cartwright and Kaide Ellis are also without deals beyond the 2020 season.
The burning question
Can Nathan Cleary steer the ship without James Maloney?
Cleary has come under the spotlight over the past two seasons for essentially taking a backseat to Maloney in the halves, serving up just nine try assists compared to Maloney's 16 in 2019.
With Maloney gone, Cleary will be the senior man alongside either Jarome Luai, Tyrone May and Matt Burton.
Cleary showed he was more than capable to handle life without Maloney with a strong performance against Cronulla in round 21 last season.
Cleary ready to lead
Breakout player to watch
The departures of Reagan Campbell-Gillard (Parramatta), Sam McKendry (released) and Tim Grant (retirement) leave the Panthers light in the engine room, despite the arrival of Zane Tetevano from the Roosters.
Spencer Leniu had a taste of first grade towards the end of last season and will be looking to grow his five-game tally.
The right judges in Sydney's west predict big things for the NSW under 20s and Australian schoolboys forward and 2020 may just be his season to cement a spot in the 17.
The quote
"I know things are ruled by wins and losses but we'll just be playing better. Our style will be a bit different – the main thing I'm working on is teamwork, leadership, connection. We are much further ahead from where we were last year and it takes a bit of time for guys to get used to it." – Ivan Cleary
Round 1 flashback: Raiders v Panthers, 2016
Preparing the Panthers: The return
'Unifying voice': Campbell honoured with OAM


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Chevron left Back to NATO after the Wales Summit
The Rt. Hon. Carwyn Jones AM
Ambassador Kolinda Grabar-Kitarović
Professor Stephen Krasner
Professor Michael Sheehan
Dr Brooke Smith-Windsor
Dr Christian Bueger
Richard Froh
Neil Brown
Professor Michael Levi
Professor Omer F Rana
Dr Jamie Shea
Frank Gardner OBE
Professor Mikkel Vedby Rasmussen
Dr Sergio Catignani
Jonathan Parish
Professor Tim Edmunds
Dr Robin Niblett
Dr Nina Græger
Etienne de Durand
Ambassador Alexander Vershbow
Sir Emyr Jones Parry
NATO after the Wales Summit
Stephen D Krasner is the Graham H Stuart Professor of International Relations at Stanford, and a Senior Fellow the Freeman Spogli Institute and the Hoover Institution. From February 2005 to April 2007 he was Director of the Policy Planning Staff at the Department of State. In 2002 he served as Director for Governance and Development at the National Security Council. He is a member of the Board of Directors of the United States Institute of Peace, and was a member of the Foreign Policy Advisory Board of the Department of State from 2012- 2014.
Before coming to Stanford in 1981 Professor Krasner taught at Harvard and UCLA. He was the Chair of the Political Science Department from 1984 until 1991, Senior Associate Dean for the Social Sciences from 2010-2013, and Deputy Director of the Freeman Spogli Institute from 2007- 2013. He edited International Organization from 1986- 1992. His writings have dealt primarily with the political determinants of international economic relations, American foreign policy and sovereignty. He is currently investigating the impact of external actors on domestic authority structures in weak states. Professor Krasner is a Fellow of the American Academy of Arts and Sciences and a Member of the Council on Foreign Relations.
His major publications include Defending the National Interest: Raw Materials Investment and American Foreign Policy (1978), Structural Conflict: The Third World Against Global Liberalism (1985), and Sovereignty: Organized Hypocrisy (1999). Publications he has edited include International Regimes (1983), Exploration and Contestation in the Study of World Politics (co-editor, 1999), Problematic Sovereignty: Contested Rules and Political Possibilities (2001), and Power, the State, and Sovereignty: Essays on International Relations (2009). He received a BA in history from Cornell University, an MA in international affairs from Columbia University and a PhD in political science from Harvard.
New horizons, new challenges. An international conference.
Email: walessummit@cardiff.ac.uk
Email: rhysjonescd@cardiff.ac.uk
This conference is supported by NATO's Public Diplomacy Division and sponsored by Cambridge University Press


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Use of Novel Technologies to Identify and Investigate Molecular Markers for Ovarian Cancer Screening and Prevention - Paving the Way for the Pacific Ovarian Cancer Research Consortium
Molecular Epidemiology of Ovarian Cancer - Australian Ovarian Cancer Study
The Biological Basis for Chemoprevention of Ovarian Cancer - The International Ovarian Cancer Association Consortium
Nicole Urban, Sc.D., Fred Hutchinson Cancer Research Center, Seattle, Washington
Dr. Nicole Urban, one of the first grant recipients from the Department of Defense (DOD) Ovarian Cancer Research Program (OCRP) has worked extensively in the field of ovarian cancer early detection biomarker discovery and validation. Her goal since 1994 has been to identify a screening strategy to reduce mortality from ovarian cancer through early detection. Her current program in translational ovarian cancer research was built on work funded in 1998 by the OCRP, "Use of Novel Technologies to Identify and Investigate Molecular Markers for Ovarian Cancer Screening and Prevention." Working with Beth Karlan, M.D. at Cedars-Sinai and Leroy Hood, Ph.D., M.D. at the University of Washington, she identified novel ovarian cancer biomarkers including HE4, Mesothelin (MSLN), and SLPI using comparative hybridization methods (1), leading to funding in 1999 from the National Cancer Institute (NCI) for the Pacific Ovarian Cancer Research Consortium (POCRC) Specialized Program of Research Excellence (SPORE) in ovarian cancer. The DOD and NCI funding allowed her to develop resources for translational ovarian cancer research including collection, management, and allocation of tissue and blood samples from women with ovarian cancer, women with benign ovarian conditions, and women with healthy ovaries. The DOD grant provided the foundation for what is now a mature specimen repository that has accelerated the progress of scientists at many academic institutions and industry. Dr. Urban has provided specimens to 133 scientists from academic institutions and 9 industry collaborators, including over 60 from outside institutions. She received the SPORE program Leadership Award in 2005 in recognition of her collaborative approach, and her SPORE grant has been competitively renewed twice.
Building on the work funded by the DOD grant, Dr. Urban developed assays to measure both HE4 (2-4) and MSLN (4-6) in serum. HE4 is an epididymal gene that is consistently overexpressed in ovarian malignancy but not in normal or benign ovarian tissue. Mesothelin is a 40-kDa glycoprotein present on the surface of many different malignancies including the majority of mesotheliomas and ovarian cancers. Using a standard set of blood samples from her repository, Dr. Urban evaluated the diagnostic performance of these (2, 6) and other markers (7-10) and their contribution to a diagnostic marker panel (11). She searched extensively for additional markers that would contribute to a diagnostic panel, identifying MMP7 for which an assay was commercially available (11). The original plate-based HE4 and MSLN assays have been licensed to Fujirebio Diagnostics Inc. (FDI), a diagnostics company that has recently received U.S. Food and Drug Administration approval for HE4 as a recurrence monitoring marker. FDI markets MSLN (as MesoMark) in Australia as a diagnostic marker for mesothelioma. Using specimen-efficient bead-based assays, Dr. Urban has evaluated top markers in preclinical samples to learn which markers give early signal. Working with Garnet Anderson, Ph.D., she used serum samples from the CARET repository, measuring CA125, HE4, MSLN, B7H4, Spondin2, and DCR3 in preclinical specimens from 34 cases and 70 matched controls. A composite marker calculated as the maximum of CA125, HE4, and MSLN begins to separate cases from controls over four years prior to diagnosis (12). Dr. Urban is also leading an inter-institutional effort to introduce the best of the novel markers into a screening protocol. She is conducting the Novel Markers Trial, a prospective randomized Phase I screening trial in high-risk women, in collaboration with Beth Karlan, M.D. (Cedars-Sinai), Jonathan Berek, M.D. (Stanford), Melanie Palomares, M.D. (City of Hope), and Pam Paley, M.D. (Swedish Medical Center).
Schummer M, Ng W, Bumgarner R, et al. 1999. Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Genetics 238(2):375-385.
Hellström I, Raycraft J, Hayden-Ledbetter M, et al. 2003. The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. Cancer Research 63(13):3695-3700.
Scholler N, Crawford M, Sato A, et al. 2006. Bead-based ELISA for validation of ovarian cancer early detection markers. Clinical Cancer Research 12(7):2117-2124.
Scholler N, Lowe KA, Bergan LA, et al. 2008. Use of yeast-secreted in vivo biotinylated recombinant antibodies (biobodies) in bead-based ELISA. Clinical Cancer Research 14(9):2647-2655.
Scholler N, Fu N, Yang Y, et al. 1999. Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma. Proceedings of the National Academy of Science U S A 96(20):11531-11536.
McIntosh M, Drescher C, Karlan B, et al. 2004. Combining CA 125 and SMR serum markers for diagnosis and early detection of ovarian carcinoma. Gynecology Oncology 95(1):9-15.
Goodell V, Salazar LG, Urban N, et al. 2006. Antibody immunity to the p53 oncogenic protein is a prognostic indicator in ovarian cancer. Journal of Clinical Oncology 24(5):762-768 [10.1200/JCO.2005.03.2813].
McIntosh MW, Liu Y, Drescher C, et al. 2007. Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma. Clinical Cancer Research 13(15 Pt 1):4422-4428.
Simon I, Liu Y, Krall KL, et al. 2007. Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer. Gynecology Oncology 106(1):112-118.
Thorpe JD, Duan X, Forrest R, et al. 2007. Effects of blood collection conditions on ovarian cancer serum markers. PLoS ONE 2(12):e1281.
Palmer C, Duan X, Hawley S, et al. 2008. Systematic evaluation of candidate blood markers for detecting ovarian cancer. PLoS ONE 3(7):e2633.
Anderson GL, McIntosh MW, Wu L, et al. 2010. Assessing lead time of selected ovarian cancer biomarkers: A nested case-control study. Journal of the National Cancer Institute 102:26-38.
Public and Technical Abstracts: Use of Novel Technologies to Identify and Investigate Molecular Markers for Ovarian Cancer Screening and Prevention
Peter Bowtell, Ph.D., Peter MacCallum Cancer Centre, Melbourne, Australia
Dr. Peter Bowtell, from the Peter MacCallum Cancer Centre in Melbourne, Australia, was awarded a Fiscal Year 2000 Ovarian Cancer Research Program (OCRP) Program Project Award to study the molecular epidemiology of ovarian cancer. With funds from this award, he and his colleagues formed the Australian Ovarian Cancer Study (AOCS), a population-based cohort of over 2000 women with ovarian cancer, including over 1800 with invasive or borderline cancer. With a bank of over 1100 fresh-frozen tumors, hundreds of formalin-fixed, paraffin-embedded (FFPE) blocks, and very detailed clinical follow-up, AOCS has enabled over 60 projects since its inception, including international collaborative studies in the United States, United Kingdom, and Canada. AOCS has facilitated approximately 40 publications, including those of the founding investigators, most of which have been released in the past two years. Findings resulting from AOCS projects include the identification of:
Differences in epidemiological risk factors between ovarian, fallopian and primary peritoneal cancer (International Journal of Cancer 2008)
New ovarian cancer susceptibility loci (Nature Genetics 2009)
Association between MDR1 genotype and progression-free survival in optimally debulked patients (Clinical Cancer Research 2008)
Novel molecular subtypes of serous ovarian cancer associated with clinical outcome (Clinical Cancer Research 2008)
Distinct mechanisms of primary treatment failure in serous ovarian cancer (Clinical Cancer Research 2009)
Since the initial OCRP award, AOCS has also been supported by Australian National Health and Medical Research Council (NHMRC), state-based Cancer Council, and Cancer Australia. AOCS was recently chosen by the NHMRC to contribute to the International Cancer Genome Consortium effort. In 2007, Dr. Peter Bowtell and Dr. Gillian Mitchell were awarded an OCRP Translational Research Partnership Award to examine the frequency of BRCA1 and BRCA2 mutations in the AOCS. Without award of the OCRP Program Project grant, this powerful enabling resource for ovarian cancer research would not have been created.
Clustering of expression data derived from serous and endometrioid tumors originating from the ovary, peritoneum, and fallopian tube. A, a series of 251 from 285 tumors were robustly clustered or classified into six k-means groups (C1-C6). Average linkage hierarchical clustering using a Pearson correlation metric was used to cluster genes based on relative expression across the 251 cancers. Per gene median normalization was used for visualization. B, differentially expressed genes identified by SAM analysis. Genes ordered to show relative position within the hierarchical cluster from A. Green, showing relative under expression; red, relative overexpression. C, differentially expressed genes identified by profiling LCM captured cells from tumor and stroma representing C1 tumor specimens. Genes are ordered based on relative position within the hierarchical cluster (A). Red, overexpressed in stroma; green, overexpressed in the tumor.
Olsen CM, Nagle CM, Whiteman DC, et al. 2008. Body size and risk of epithelial ovarian and related cancers: A population-based case-control study. International Journal of Cancer 123:450-456.
Song H, Ramus SJ, Tyrer J, et al. 2009. A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nature Genetics 41:996-1000.
Johnatty SE, Beesley J, Paul J, et al. 2008. ABCB1 (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/carboplatin chemotherapy. Clinical Cancer Research 14:5594-5601.
Tothill RW, Tinker AV, George J, et al. 2008. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clinical Cancer Research 14:5198-5208.
Etemadmoghadam D, deFazio A, Beroukhim R, et al. 2009. Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas. Clinical Cancer Research 15:1417-1427.
Public and Technical Abstracts: Molecular Epidemiology of Ovarian Cancer
Andrew Berchuck, M.D., Duke University, Durham, North Carolina
In 1997 Dr. Andrew Berchuck at Duke University, along with his colleagues, was awarded an Ovarian Cancer Research Program (OCRP) Program Project Award to investigate the biological basis for chemoprevention of ovarian cancer. In 2001, he received another Program Project Award to continue this research.
Although inherited BRCA1 and BRCA2 mutations are responsible for about 10% of ovarian cancer cases, these mutations are carried by less than 1% of the population. Other genetic factors likely exist that increase risk moderately, and by virtue of being more common, they may account for a significant fraction of cases. One of the aims of the Program Project was to perform an ovarian cancer genetic association study to identify common low penetrance risk alleles. Over 1,300 cases and an equal number of age- and race-matched control subjects were accrued to the North Carolina Ovarian Cancer Study.
Although Dr. Berchuck and his research group were thrilled by the enthusiasm with which their study was embraced locally, it became apparent that much larger studies would be needed. As the OCRP Program Project was ending in 2005, Dr. Berchuck and his colleague, Joellen Schildkraut, Ph.D., had the opportunity to help lead the formation of an international Ovarian Cancer Association Consortium (OCAC) that is now comprised of over 20 groups. The consortium meets biannually and is working together to identify and validate single nucleotide polymorphisms (SNPs) that affect disease risk through both candidate gene approaches and genome-wide association studies (GWAS). OCAC reported last year in Nature Genetics the results of the first ovarian cancer GWAS, which identified a SNP in the region of the BNC2 gene on chromosome 9 (Nature Genetics 2009, 41:996-1000.)
Dr. Berchuck and his colleagues envision a future in which reduction of ovarian cancer incidence and mortality will be accomplished by implementation of screening and prevention interventions in women at moderately increased risk. Such a focused approach may be more feasible than population-based approaches, given the relative rarity of ovarian cancer.
Public and Technical Abstracts: Biological Basis for Chemoprevention of Ovarian Cancer


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While every Patty Griffin album features a variety of styles and approaches, it's the stark, eerie ballads that never fail to entrance and hypnotize. Children Running Through is no exception. "Stay on the Ride," "Getting Ready" and "No Bad News" are the uptempo cowboy boot kickers and they're tight and exciting, but the moments that truly draw attention are the great quiet spaces where Griffin's voice is given full stage. The album's opener "You'll Remember" begins things with a cathedral-like echo, as a stand-up bass stalks her every move. "Trapeze," a duet with Emmylou Harris, gently observes the dark human side that savors the failure of others: "one of these nights the old girl's going down." Her version of "Up to the Mountain (MLK song)," a track covered by Solomon Burke on his Nashville collection with Griffin providing back-ups, is included here and proves she's got the gospel pipes to deliver. String arranger and conductor John Mark Palmer effectively shades these songs with touches of cello, violin and viola, creating a cinematic tension to Griffin's quick portrait of a childhood busride to Bangor ("Burgundy Shoes") and the self-motivating anthem "I Don't Ever Give Up."
Children Running Through Patty Griffin
You'll Remember
Stay On the Ride
I'm Gettin Ready
Heavenly Day
No Bad News
Railroad Wings
MLK Song
Don't Ever Give Up
Someone Else's Tomorrow
Crying Over
℗ 2007 ATO Records, LLC.
More By Patty Griffin
Living with Ghosts
Downtown Church
Impossible Dream
1000 Kisses
American Kid
Flaming Red
Down Where the Spirit Meets the Bone
Ruth Moody
Bright Morning Stars
The Wailin' Jennys
Lori McKenna
Lucy Kaplansky