Currently on our screens as endearingly eccentric nun Sister Monica Joan in Call the Midwife, Judy Parfitt has enjoyed a long and proclaimed acting career. Lisa de Silva meets Judy in her Mid Sussex home where they talk acting, family and being an ambassador for Dementia UK.
A doyenne of stage, television and film acting, Judy Parfitt has worked alongside everyone from Laurence Olivier, Peter O'Toole to Anthony Hopkins and even Madonna, enjoying a remarkable career in terms of both its diversity and longevity. Most recently seen on our screens in the BBC drama, Call the Midwife, as Sister Monica Joan, I met up with Judy to discuss her career, her role as an ambassador for Dementia UK and her love of the Mid Sussex countryside where she has lived for nearly forty years.
To enjoy a career in any profession for over six decades is an exceptional achievement, but to achieve this in the fickle and perfidious world of acting is extraordinary. Yet despite all her success, Judy echoes the advice of Noel Coward to Mrs Worthington, to not put your daughter on the stage. "I would say to anyone thinking about acting as a career not to do it, because it's too hard and too few people succeed. My American agent once said to me, if you have to choose between talent and luck, choose luck every time, because it's not just about how talented you are as an actor, it's how resilient you are, how determined you are and how you can bounce back from constant rejection. To keep going you have to need it desperately and I wouldn't advise anyone to do it unless they feel they would die if they don't," she confides.
For those still determined to tread the boards Judy advises, "You have to take your acting seriously but not yourself. Always monitor your performance and constantly look for ways to improve and learn. I'm still learning all the time, I see someone do something on the television and think that was amazing. I'd also advise young actors not to believe their publicity. Young actors often get lots of attention from the press because they're young and fresh and they love a new face. They build these people up but then move on to the next new face and the others disappear, so you need to be down to earth and with lots of common sense so you don't get carried away. It's also important to take jobs that may not seem exciting or interesting, because if casting directors don't regularly see you performing, they forget about you. So sometimes you just have to do things to be seen," she tells me.
Smart, straight talking and down to earth, Judy was born in Sheffield where she attended a convent school, before moving to London at the tender age of fifteen and a half, to take up a place at the Royal Academy of Dramatic Art. In retrospect, she admits that maybe this wasn't a good idea. "My parents were very worried because at that time the Arts were the only place where you didn't have a pension or a secure job, but I just wanted to act, it was a driving passion for as long as I could remember," she explains.
Looking back on her career though, Judy admits to being very lucky at the mix of work she has had the opportunity to pursue. During her younger years she was a regular at the Royal Court and has appeared on stage alongside such luminaries as Laurence Olivier, Paul Schofield and Joan Plowright. She has been BAFTA nominated twice, once for her performance in the 1984 television drama, The Jewel in the Crown and again for her part in the 2003 film, Girl with a Pearl Earring.
Working in America also gave Judy an insight into the US entertainment industry, where top shows, including at that time, The Charmings, are routinely subjected to audience testing. "I remember they came to me and they said, your rating has gone through the roof. The producers were all over me like a rash, but I can remember thinking although it's nice to hear all of this praise and adoration, thank God I'm a down to earth Yorkshire girl in my forties who doesn't believe any of it," she laughs.
One of the great things about her time in Los Angeles though was renting a house in the Hollywood Hills and experiencing life as a movie star. "I'd come home from work, swim in the pool and my husband would bring me a glass of wine and I'd think, this is what it's all about. I can see how you could get used to living like that," says Judy, with a flash of amusement in her strikingly blue eyes.
In 2012, Judy took on the role of the marvellously eccentric nun, Sister Monica Joan in the BBC drama, Call The Midwife. "She is a mixture of senility and old age, but only really loses the plot when she's ill, upset or frightened and she can't cope. It's this overload that makes her slightly demented, but lots of times she can handle things in her own strange way, although she's clearly not playing with a full deck," Judy explains.
Judy and Tony moved down to Mid Sussex from Hertfordshire thirty-eight years ago. "We used to go down to Brighton to the Royal Crescent for weekends and as I love being near the sea we decided to relocate. Mid Sussex was the obvious choice as the villages are so lovely and it's convenient for London and the airport," she tells me.
I leave wondering if it's this wonderful no nonsense and pragmatic approach to her life and acting career that has allowed Judy Parfitt to build and continue to build, such a fine and diverse body of work.
Dementia UK need funds for more Admiral Nurses, please go to www.dementiauk.org to see how you can get involved.


All sales are final. We accept cash, check, credit card.
Huge multi estate sale featuring items from the Chanteloup mansion and multiple estates. Beautiful lamps, stressless sofa, antique clocks, Stickley furniture,outdoor iron chairs, sterling silver, sterling rings, fine china, dining table and chairs, antique bedroom sets, dining tables and chairs, gun cabinet, and much more!


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Our Insider Hong Kong tours show you facets of the city that other travelers rarely see. Used by local residents for their daily commute, the Star Ferry is the best way to cross from Kowloon to Central, Hong Kong's business district. The commuters may have their heads buried in their newspapers, but you'll taking in the sight of Victoria Harbor, busy with ships and sampans.
Once on Hong Kong Island, you can explore from the skyscrapers of Wan Chai to the antique stores of Hollywood Road. See iconic landmarks like I.M. Pei's China Bank Tower as our expert guide explains how Feng Shui principles still guide Hong Kong's urban planners. At Man Mo Temple, you can learn about the old traditions that still endure in this modern city. Of course, no Hong Kong trip would be complete without a ride on the famous Peak Tram. From the top of Victoria Peak, you'll have breathtaking views of Victoria Harbor, Hong Kong Island and Tsim Sha Tsui.


Aloha SUP'ers and mahalo for dropping in with Blue Planet Surf. One of the most frequent inquiries we get at our shop in Honolulu, Hawaii is how does one determine what size and type of board is right for them. As avid water enthusiasts, our main objective at Blue Planet Surf is to provide sufficient info to potential paddlers, so that they are equipped with the best knowledge to make the best decision when buying their first or additional boards for their quiver. With the right knowledge, one can choose the ideal board to suit their surfing and paddling needs and ultimately have more fun on the water.
Thank you to our customers for voting Blue Planet as Hawaii's Best Stand Up Paddle Shop.
Below you'll find 12 images and graphs that will help you with the complex process of finding the right board(s) for you.
As a surfer of many years (bodysurf, bodyboard, shortboard, longboard, and Stand Up Paddleboarding), I personally consider over 100 different variables when I'm choosing my own boards. For a first time SUP buyer, it would be excessive to consider so many variables, so we wanted to simplify the process for our customers.
The boys at the shop and I were able to narrow a potential paddler's focus down to 12 basic points which we use at our shop in Hawaii every day to help our customers find the perfect stand up paddle board for them.
Keep in mind that surfing and paddling needs are very specific to the rider and their locale, so our images and graphs may not depict info that is 100% accurate for you and where you plan to use the board.
If you have any questions about it contact Blue Planet Surf in Honolulu, Hawaii; or consult your nearest SUP/surf shop for more info.
First and foremost, the paddler must consider what type of paddling they intend to do. By determining if an individual will be surfing, racing, cruising or doing a hybrid of those, they will have already narrowed their board selection down.
In general, the shorter and smaller the board is, the more surfable and maneuverable it will be, while the longer and more streamlined the design is, the more efficiently the board will cover distance and the better the board will be for racing. For cruising, one should consider boards that are in between those two spectrums, and skew their choice either shorter or longer depending on how they want their board to perform.
Height and weight, along with skill level, are the next big factors an individual should pay close attention to. Because paddle boarding requires the board to be on top of the water at all times (different from shortboards where the board may be fully submerged when not planing on a wave), height and weight dictate the amount of floatation the board will need to offer.
If there were twin brothers who grew up in the state of Hawaii and all variables for them are constant other than the fact that one spent the majority of his time in the library while the other spent the majority of his time on the soccer field, we can rationally conclude that the brother with an athletic background would probably do a little better the first time on an SUP than the brother who enjoyed the library.
With that info, determine what type of paddler (6 choices) you could be most readily characterized as, determine your current weight and match up the recommended volume via the chart.
It is important to account for the type of waters you will be paddling in as specific boards are designed for managing different types of environmental conditions.
In general, the fuller the outline of the board, the more stable the board will be and the better it will be for cruising in calm conditions, whereas the more pointed the outline is, the more control and displacement the board will offer, making it ideal for windier or choppier conditions.
Oceans, lakes, rivers, and other bodies of water offer many different environments for paddling so the main thing to consider is how frequently will you be in each of those conditions and choose board shapes and sizes that are most conducive to optimizing performance in those environments.
By carefully considering those points, you may or may not want to choose a board that will allow you room for growth so you don't progress out of a board too fast and need to buy another one. Keep in mind, there's nothing wrong with owning multiple boards (quiver) to offer variable performance if conditions vary where you paddle or surf.
The length of the board is measured from the tip of the nose to the tip of the tail. When it comes to the length, the basics to remember are that longer boards are faster while shorter boards are more maneuverable.
In general, surf SUPs are in the 8'-10' range, cruise and recreational SUPs are in the 9'-11' range, touring boards are in the 11'-12' range and race boards are usually 12' and longer.
The width of your board is the most influential factor in the overall stability of the board. It is measured from the absolute widest point on the board and could be forward or back relative to the middle of the board from nose to tail.
Like anything else in the SUP/surf world, if we gain something on one end, it's because we're giving up or sacrificing something on the other end. Although wider boards offer greater stability, they decrease the overall speed and responsiveness of the board due to the additional surface area.
In general, performance surf and race SUPs are 26"-30", intermediate SUPs are 29"-33", and beginner boards or boards designed for taller and/or heavier individuals are usually 33" or wider.
Of all the dimensions for one to be aware of, thickness is probably the least important because it can sometimes be a very misleading variable. Do not disregard the thickness variable all together, though, but pay close attention to volume (thickness) distribution from the nose to the tail and from the stringer (middle of board) out to the rails.
The thickness, like width, is measured at the absolute thickest part of the board, which is usually by the stringer and belly of the board. If the board has a flat deck, the thickness is pulled farther out to the rails which will result in more floatation and stability.
If the board has a convex deck, the thickness tapers out toward the rail and will usually offer less floatation but greater surf performance. Most surf SUPs are between 3.5"-4.5" while most recreational, touring and race SUPs are between 4.5"-6".
Volume is a great factor to be aware of in the surf world and an even more important factor to be aware of in the SUP world. That being said, don't rely on volume as the most influential determinant of what board is right for you as you must always assess boards from a holistic point of view, accounting for as many variables as possible.
Unlike surfing where the speed on a wave generates planing and lift, SUPs should offer a good amount of floatation even when not moving. Height, weight, board function and paddler skill level are the four most important things to look at when figuring out the appropriate volume for your SUP.
Choosing a board with too much volume may inhibit performance, especially in the surf, while choosing a board with too little volume will result in a general lack of floatation relative to the rider. One of the best ways to figure out proper volume for you as a paddler is to utilize the Blue Planet SUP Board Volume Recommendation Chart. It uses 3 of the factors mentioned above and can give you a pretty solid idea of what volume you should consider with a simple mathematical calculation.
The basics of the volume recommendation chart are to take your weight in kilograms and multiply that weight by a factor between 1.1 and 3. The lower the multiplying factor the more performance and surf oriented the board will be, whereas the higher the multiplying factor the easier or race oriented the board will be. Determine where you fall in the chart and utilize the appropriate multiplying factor for you.
When it comes to the nose of your board, one of the easiest ways to simplify understanding the design and thus performance is by looking at the surface area. In general, you have pointed noses with less surface area (sometimes referred to as displacement hulls) and full noses with more surface area (sometimes referred to as planing hulls).
With pointed noses you have increased maneuverability, increased displacement, increased speed, less drag and less stability. Fuller noses offer nose riding performance, better planing, increased stability, and increased drag.
In the surf world, if you like maximum maneuverability from the tail and don't need any nose riding capabilities, look for more pointed noses.
In the recreational SUP and race world, pointed noses offer better displacement in calm and choppy conditions. Fuller noses allow for longboard style surfing with the ability to nose ride, and provide additional stability in calmer flat water conditions. On the downside, fuller noses are less than ideal for managing open ocean conditions, or waters with lots of texture and chop.
The tail of your board has similar properties to the nose in the sense that surface area is the main consideration to be looking at. Fuller tails offer a better planing surface for increased glide and speed but have looser control and maneuverability, whereas more pinched in tails offer less planing surface for better control and tighter turning, especially in the pocket.
For bigger wave high performance SUP surfing, looking for less surface area in the tail to contribute to more control in those steeper and hollower sections.
For small wave SUP surfing, choose slightly fuller tails to help generate and maintain speed with looser turning.
In the flat water and race SUP world, choose tails with less surface area if you're paddling in rougher conditions to provide additional control or choose tails with more surface area if you're paddling in glassy, calm water conditions to increase planing surface and glide.
The rail design of your board is influential in the stability and surfability of the board. There are an infinite numbers of ways to design a rail (like everything else in board design) when taking into account angles and transitions from the nose to the tail (soft rail to hard rail).
To oversimplify it, you can look at the rail design in the standing area of the board (usually 1'-2' in front and behind the handle) to determine what kind of performance the board was designed for.
The thicker and boxier the rail is (more volume pulled out to the rails), the more stable the board will be and the better it will be for racing, touring and cruising. The thinner or more tapered off the rail is (less volume pulled out to the rails), the better the board will be for holding a rail in the face of the wave when surfing and controlling your turns. Thinner rails also allow for better control in rail to rail surfing and faster responsiveness on a wave.
As surprising as it may sound, rocker line is one of the most important components of board design in the surf, SUP and race world. Coupled with the board's outline, most shapers (especially in the high performance shortboard world) will tell you that rocker line is a make it or break it factor for board performance.
To oversimplify the rocker, flatter rockers mean more speed while increased rocker lines mean better turning in the surf or better management of open ocean conditions in SUP racing. When looking at the rocker for your first board, the best thing to consider is what type of conditions are you surfing or paddling in.
Usually for higher performance surfing, you'll want more exaggerated rocker lines, whereas flat water recreational paddlers and racers look for flatter rockers to maximize speed.
Because we are blessed enough to be in the state of Hawaii, I personally own 4 alaias, 3 bodyboards, 22 shortboards, 3 longboards and 9 SUPs. Most people are shocked at the number of boards I've collected over the years, but the truth is I love having an excessive number of boards in my quiver to choose from (much to my girlfriend's chagrin as they take up a lot of space). By having a diversified selection of equipment at my disposal, I can check the surf forecast and bring the best board of my quiver to have the most fun on any given day at any given break. The easiest way for the non-surfer to understand this insanity is to think of boards like golf clubs. If you're on a par 5 hole, it wouldn't make sense to use a putter to tee off, just as much as it wouldn't make sense to use an iron to putt on the green. Every board (if shaped properly) is designed for a very specific and definitive purpose and having many different boards allows for one to have the best stand up paddle board to be able to play in many different and varied conditions to the best of their ability.


"Hurricane Michael is a massive storm that could bring total devastation to parts of our state, especially the Panhandle", Scott said.
The National Hurricane Center says Michael is now a hurricane and will continue to strengthen as it approaches US. "It is forecast to move very quickly and there would not be the rain like we had before". HAZARDS AFFECTING LAND -------- WIND: Tropical storm conditions are expected to first reach the coast within the warning area by this evening or tonight, making outside preparations hard or risky.
As forecast, Michael would be the first Category 3 or higher hurricane to hit the Panhandle since Hurricane Dennis in 2005. A hurricane watch was in effect from the Alabama-Florida border to the Suwannee River area.
The storm was centered about 30 miles (80 kilometers) off the western tip of Cuba, and about 520 miles (835 kilometers) south of Apalachicola, Florida. A Storm Surge Watch has also been issued from Navarre, Florida to Anna Maria Island, including Tampa Bay.
Alabama Governor Kay Ivey issued a state of emergency order Monday after concerns of severe weather and possible damages were raised. The threat along the coast includes serious storm surge.
Escambia through Franklin counties in Northwest Florida are included in the hurricane watch.
The chances of tropical storm winds are low but it is possible that strong gusts Tuesday night into Wednesday might reach tropical storm force. These chances could go up as we get greater confidence in the forecast.
Interim Emergency Management Chief Steve Litschauer said several county and Anna Maria Island officials had a conference call with state National Hurricane Center partners Monday to discuss the county's response to Hurricane Michael.
The governor noted that while state officials are prepared for the storm, she said "now is the time for residents in south Alabama to review your emergency preparedness plans and also get prepared" - warning that those in Michael's path "will need to take shelter by [Tuesday] evening".


text:
Chains of Gold is a 1991 American made-for-television crime drama film starring and co-written by John Travolta. It was directed by Rod Holcomb and included one of the early performances of Joey Lawrence, who was nominated for Young Artist Award for his role in the movie.

The film premiered on Showtime on September 15, 1991 in United States and was released theatrically in Germany. It was released to DVD on December 15, 1998.

The opening credits state that Chains of Gold is "based on actual events", though details of the actual events themselves remain difficult to pin down.

The film was shot in Miami, Florida, USA. It is the only film so far written by twice-nominated Academy Award actor John Travolta.

Plot
Scott Barnes (Travolta) is a former ad executive turned social worker living in Miami. He is also a recovering alcoholic who stopped drinking after accidentally killing his son in a drunk-driving accident. One of his cases is Tommy (Joey Lawrence) a street kid who has been selling crack for an organization called the Youth Incentive Program (YIP). Barnes is unaware of this, but suspects something when Tommy buys expensive gifts for his mother and sister. He also notices the YIP tattoo on Tommy's arm.

Tommy is kidnapped by YIP and forced to package crack into vials in an abandoned building with many other children. After Tommy does not come home for several days, his sister calls the morgue and they inform her he is dead. Barnes goes to the morgue to identify Tommy, but discovers it is not him, although he sees the YIP tattoo on the corpse. While trying to find Tommy, he witnesses a shootout where one of the gunmen has a YIP tattoo. He goes to see Sgt. Palco (Bernie Casey), who tells him about YIP. Barnes, convinced Tommy has been kidnapped by YIP, then talks to the head of the narcotics division, Lt. Ortega (Hector Elizondo) who tries to convince him to stay away from the gang.

While looking for Tommy in the streets, Barnes notices the YIP henchman James (Ramon Franco) and follows him to a nightclub. There, he meets his old girlfriend Jackie (Marilu Henner) and is shocked when he sees her speaking to James. After sleeping together, Barnes learns Jackie is a lawyer for YIP and tells her he wants to get into the organization to rescue Tommy. After some consternation, Jackie tells Barnes that YIP is willing to induct him as a member.

Barnes goes to meet with Carlos (Benjamin Bratt), the head of YIP, who wants him to help expand the organization into the suburbs. James then shows him around the organization and leads him to the warehouse where Tommy is being held. Tommy tries escaping and is taken to the Madison House, an abandoned factory where members of YIP who commit transgressions are killed. Barnes finds out about this from one of Tommy's friends. Barnes is taken to the Madison House and sees Tommy. He then goes to see Lt. Ortega, who tells him if he interferes further, he will be charged with conspiracy to distribute narcotics. One of Carlos' henchmen sees Barnes enter the police station and informs Carlos, who now believes him to be an FBI agent.

Barnes goes to see Jackie and discovers that she has been killed by Carlos' henchmen, who then attack him. Barnes escapes but is quickly kidnapped by the henchmen. He is taken to the Madison House and thrown into an elevator pit filled with alligators, but gets caught in the wiring and manages to escape. Barnes finds Carlos and the two have a fist-fight just as the police raid the building. Barnes finally manages to punch Carlos down into the elevator pit, killing him. The police arrest the rest of the YIP members and Barnes drives away with Tommy in a police car.

Cast
John Travolta as Scott Barnes
Marilu Henner as Jackie
Héctor Elizondo as Lieutenant Ortega
Joey Lawrence as Tommy Burke
Bernie Casey as Sergeant Falco
Benjamin Bratt as Carlos
Conchata Ferrell as Martha Burke
Tammy Lauren as Rachel Burke

References

External links

1991 television films
1991 films
1991 crime drama films
1990s action films
American crime drama films
Films shot in Miami
Showtime (TV network) films
Films scored by Trevor Jones
Films about runaways
Films directed by Rod Holcomb
American drama television films
1990s English-language films
1990s American films

redpajama_set_name: RedPajamaWikipedia


Northwest Folk Dancers Incorporated (NFDI) is a non-profit "umbrella" organization that promotes folk dancing and ethnic events in the Pacific Northwest. NFDI sponsors folk dance festivals and other folk events, provides dance descriptions and practice tapes at a nominal charge for NFDI members, and seeks new ways to promote all forms of ethnic dance.
NFDI publishes a monthly magazine, The Northwest Folkdancer, containing articles and advertisements of interest to the folk dance community. One of the most popular features of the magazine is the listings of regular dances and classes and a separate comprehensive calendar of special events. The magazine also contains club news, ethnic recipes, dance descriptions, CD reviews, and other information helpful for dancers, teachers of folk dance, and anyone interested in the food, dances, costumes, and history of other cultures.
NFDI also provides scholarships for adults who want to attend folk dance camps and who agree to teach the dances to other NFDI clubs, and youth scholarships for students (high school and college age) who want to participate in a dance camp but need assistance to do so.
The Northwest Folkdancer, a magazine.


Meals Manager Anne Sale helps Treanor Granbery unload 345 pounds of cabbage donated from the Granbery farm. Meals Coordinator Makisha White is excited to include this beautiful green and purple cabbage in our meals this week. A huge thank you to the Granbery family for their generosity!


chrissstttiiine: New York, I love you, but you're bringing me down.
Those boots are amazing. Who are they by?
I love this post and seeing your NYC adventures!!!
Nice, they're pretty damn awesome. Hawaii needs more vintage shops. We're definitely lacking in that department.


text:
using System;
using System.Text;
using System.IO;
using RestSharp;
using RestSharp.Extensions;
using RestSharp.Deserializers;
using SugarRest.Model;
using Newtonsoft.Json.Linq;

namespace SugarRest
{
    public partial class SugarClient
    {
        /// <summary>
        /// Upload a file to a note record.
        /// </summary>
        /// <param name="module">Module name (Notes)</param>
        /// <param name="id">record ID</param>
        /// <param name="filePath">Path to file on local disk</param>
        /// <returns>Bool</returns>
        public bool UploadFile(string module, string id, string filePath)
        {
            return UploadFile(module, id, filePath, false);
        }

        /// <summary>
        /// Uploads a file, if the request fails this overload will delete the note record
        /// </summary>
        /// <param name="module">Notes</param>
        /// <param name="id">Record ID</param>
        /// <param name="filePath">Path to file on local disk</param>
        /// <param name="deleteOnFailure">Bool: deletes record if upload fails</param>
        /// <returns>Bool</returns>
        public bool UploadFile(string module, string id, string filePath, bool deleteOnFailure)
        {
            var request = new RestRequest("{module}/{id}/file/filename", Method.POST);
            request.AddUrlSegment("module", module);
            request.AddUrlSegment("id", id);

            request.AddParameter("format", "sugar-html-json");
            request.AddParameter("delete_if_fails", deleteOnFailure);

            if (deleteOnFailure)
            {
                request.AddParameter("oauth_token", Token);
            }

            if (!File.Exists(filePath))
            {
                //@todo create a SugarFileException class
                throw new SugarException("Can not locate file path. Path attempted = " + filePath);
            }

            request.AddFile("filename", filePath);//?

            FileUploadResponse response = Execute<FileUploadResponse>(request);

            return ! string.IsNullOrEmpty(response.filename.name);
        }

    }
}

redpajama_set_name: RedPajamaGithub


Opening Ceremony has launched their first kids' line in collaboration with, A is for Apple, Hong-Kong based 'hipster' kidswear brand. The line which is intended for boys and girls from 6 months to 6 years, kept Opening Ceremony's signature looks and silhouettes, but now perfectly adapted for the little ones. Their first, summer 2011 collection is inspired by French Riviera storytelling and abounds with a variety of summer weather essentials, such as dresses, jackets, blazers, shorts, patchwork oxfords and shirts in adorable colors, prints and patterns.


Great. Just great. In all of the years and times we have rented vehicles, we have never returned one with damage. Even though this doesn't look too bad we are pretty sure that we will get over-charged substantially for this one. Let's see how the Amex rental car insurance works. Nothing else to do but continue on.
After a bit of juking and jiving and trying to figure out exactly which car line to be in, we manage to park our car in the Vis line around 9:00 so that we can scoot back in town for breakfast.
Our host for last night had told us about a great local place for breakfast and Janel expertly navigates through the streets of Split ending up at Bistrot Toc.
Janel and Rich go for omelets and I choose the Dalmation breakfast of tuna, cheese and olives. A couple of lattes later and we are happy.
Soon Vis comes into sight. We go up top to get the full view of our next home port.
Vis looks gorgeous from the water. When I was researching Croatia I knew we wanted to spend time on one of its many islands. I chose Vis because it was less touristed than others and it just looked like our kind of place. We will be spending 3 nights here and are looking forward to putting down some "roots" at least for a while.
When the ferry docks and we drive our car off we see a man standing and holding a sign "Lemon." We will be staying at Lemon Vis apartment and have been told by the owner (Berti) that he will be waiting for us at the ferry dock. Fantastic! Berti tells us where to meet to find our parking space. We take a wrong turn (which is hard to do in this little town), but eventually find our way back to Berti.
The Lemon Vis apartment intrigued me online immediately. It is part of an historic baroque stone building from the 17th century and simply oozes charm. Just walking the narrow cobblestone street to it is great. I think we will love it here.
There is a large living area, small kitchen, bathroom, large master bedroom and a nice little loft bedroom for Janel.
I am happy to see that there are two A/C units. However the windows are open and a nice cool breeze is flowing through. Maybe we won't even need the A/C.
"Almost completely obscured from the view of passing boats, Stiniva beach on the Croatian island of Vis has something of the James Bond villain lair about it.
But its secret is out. This week it was named the top beach in Europe for 2016 by the Brussels-based tourism organisation European Best Destinations following a poll of more than 10,000 holidaymakers.
Well alright. It can't possibly get any better than that. Berti had mentioned Stiniva to us but warned that the hike down (and especially back up) could be grueling. Do NOT attempt in flip flops.
On the way to the beach we make a stop in Milna Bay to check on the possibility of Stand Up Paddleboarding for tomorrow with Islomania Vis. I have been in touch with the owner, Lea, and she told me to check with her regarding conditions when we are here.
Evrything is very laid back here. No firm plan or time is set – we just tell her we will show up between 8:30-9:00. She says the boat will be there and we can decide what we want to do when we arrive..
With the expert assistance of our navigator (Janel) we motor on and easily find the entrance to Siniva's hiking path.
We are rewarded when we reach the bottom.
We are not really beach folk, but this is hard to beat. We people watch and chill. At one point Janel decides to try the water, but quickly finds out that the small round rocks on the beach are extremely painful to try and walk on. We both don our flip flops to get to the water's edge but it is way to cold for me to get in (water temp probably in the 70's but I am a wimp with cool water).
The people watching is great, but it is even better when most of the boats and people leave.
Nope. Can't get any better.
It is tough going back up. Fortunately it is not hot or I would really be whining. Somehow we got off the trail and ended up scrambling up sheer rocks and making our own path. In the end we figured we cut out about 30 minutes of walking that way! It actually took longer to go down than up.
Stiniva was a great choice with which to begin our exploration of Vis. I think we are going to like it here.
We head back home and get ready to go out for the evening. Tonight we will have dinner at Pojoda. This restaurant was highly recommended to us both by our hosts at Villa Sumrak and also on TripAdvisor. We are eager to have more fresh fish!
On the way to Pojoda we find a tiny bar situated directly on the water. This looks like the perfect place for a couple of Aperol Spritz.
Pojoda awaits and we are hungry from our hiking.
We let our server lead the way tonight. We have found (especially on this trip) that it pays to ask the waiter what we should order. He does not disappoint. We are presented with a "Shrimps from My Grandfather, a zucchini ragu and octopus "balls" to start. The octo is a standout.
Soon we are presented with a tray of the fresh catch so that we may choose our fish. Various varieties are available, but the server steers us towards the John Dory. (I remember having it only once in NYC when Eric was paying $$$$ – It was a memorable dish!). We will have the JD.
After being grilled, the John Dory is filleted tableside.
We are hoping he doesn't take the skeleton away. Thankfully, he leaves all the pieces and parts.
The fish is absolutely divine. We devour the fillets and then start in on the bones.
Not a morsel is left when we get through. For dessert we choose a typical fig "bar" that our server tells us is the original energy bar in Croatia. A Grappa-like digestiv is served alongside.
If this is what life is like on Vis, sign me up.


How Spray Foam Insulation Aids In Soundproofing It is not uncommon especially in recent times to walk into your neighbor's house and get insects and bugs all over flying. Presence of such pests is embarrassing to the owner of the home because they do not look good. There is however, a way of dealing with all these and this is by using a chemical known as spray foam. Spray foam is a chemical that is used in insulation of homes to prevent unwanted entry of foreign materials into your home, it becomes bigger even when sprayed in small quantities. This chemical product is used in buildings when you are building a home and especially the foundation. A lot of professionals in the construction sector are opting for spray foam due to the benefits that come about with it for example you can reduce noise a lot in your home. Spray foams are beneficial in that they will insulate your home making it more suitable for you to live in. Just like other products, spray foam comes in different varieties and the choice of each will depend on what you needs and preferences actually are, some are more pricey than others. Spray foam insulates your home by forming a barrier between it and the outside world and thus nothing that is from the outside can come in. One of the major advantage of spray foam is that it is ranked among the top insulation materials for homes and that is why a lot of people prefer them.
Spray foam has the ability to become bigger after being sprayed on a small space and this makes it to spread all over the wall covering up any cracks that might be present. Spray foam seals your home entirely and this means that there will be no such things like insects and bugs that will be bothering you, you can also say goodbye to pollens and other allergens thanks to spray foam. The noise reducing abilities of spray foam is beneficial in that you can be able to focus on your things better without being distracted for example if you are studying or working. The heavy nature of spray foam is beneficial also since it adds some weight on the wall and this increases its tensile strength making it less likely for it to collapse.
Water entry will be a nuisance to you especially because molds will grow as a result, to prevent this from happening to your home, you can use spray foams. You only need to use spray foam on your building very few times and the effects will last long.


Find your passions and self-esteem will follow!
Confidence is something we are born with, develop over time and experience through our passions or hobbies.
It is extremely important as an entrepreneur, kid or otherwise, to have confidence.
Confidence gives one the power to pitch their ideas, make vital decisions, and put their best foot forward. It's also a necessary trait in building a network of likeminded individuals and investors.
Every parent and teacher wants students and/or kids to have this trait. However, it may seem difficult to develop in a classroom or home setting.
Kebloom helps identify young people's passions and skills. In this way they can work on their existing skills and create new ones. Passion is similarly fundamental for building confidence. For instance, passion can help young people establish self-awareness, embrace uncertainty and grow their connections.
As a result, young people become surer of their abilities, building their inner motivation to work harder on projects and in achieving their goals.
Every kid has that spark of confidence already in them; Kebloom is simply the catalyst.
Help make their dreams, their reality.


Odd and even ash keys (seed-pods) were often used in divination.
Sandalwood has many magickal uses, including protection, spirituality, exorcism, healing, and wish fulfillment. Scatter sandalwood powder around your home to clear it of negativity. Use in healing and exorcism spells. Write a wish on a sandalwood chip and burn in your cauldron. As it burns it sets your magick flowing. Sandalwood mixed with Lavendar makes a wonderful incense which is intended to conjure spirits.
This is useful for protection, healing, wealth, fulfilling wishes, and spells to increase longevity. One of my favorite uses for Sage is to powder some and add to my homemade yellow candles. These I burn on a Wednesday during the Waxing Moon to increase knowledge and wisdom.
This is a wonderful all-purpose herb that you can't afford to be without! Rosemary can be used as a substitute for just about any herb. Its powers include love, lust, protection, exorcism, purification, healing, longevity, youth, mental powers, and sleep...Rosemary is a wonderful incense...smoulder a bit of it to emit powerful cleansing and purifying vibrations and to rid negativity in the area in which it is burned (especially helpful to burn before performing any magick!) Place a bit of rosemary under your pillow to ensure a good night's sleep. Wear rosemary to aid your memory (especially helpful when you are studying for an exam). Add an infusion of rosemary to your bathwater to perserve youthfulness and to purify you. Carry a bit of rosemary with you to remain healthy. Hang a sprig of rosemary above your door posts.
toothaches, and for the removal parasites such as lice.
Traditionally the Celts were a nomadic people. They camped on one place throughout the cold winter months, and would break camp in the spring when the first yellow blooms appeared on the broom. Although it has associations with spring, broom stands for the month of October in the Ogham Calendar.
The ivy is not considered a tree, but depends on a host tree for support. Ivy belongs to the evergreen family, and oversees the month of September. It's leaves are deep green and rather waxy, and it has thin tendrils that attach themselves to surfaces, and are strong enough to force their way into bricks, cracks, and plaster. Ivy can grow in such abundance on a host tree that it smothers the tree and actually kills it.
Ivy berries can be used for medicinal purposes, but can be poisonous if taken In large quantities. A broth of fresh leaves can be used to cleanse sores or wounds. A powder made from dried leaves and berries can be used to clear stuffy heads, and is also believed to be a cure for hangovers.
The Ivy was considered to be a very powerful tree to the Celts because of its ability to kill even the mightiest Oak tree. Because of its tendency to create dense, inpenetrable thickets in the forest, it is seen as more powerful than the vine, and rather sinister in nature.
Honey fungus or Armillaria is a genus of parasitic fungi that live on trees and woody shrubs. It includes about 10 species formerly lumped together as A. mellea.
Armillaria is long lived and form some of the largest living organisms in the world. The largest single organism (of the species Armillaria ostoyae) covers more than 3.4 square miles (8.9 km²) and is thousands of years old. Some species of Armillaria are bioluminescent and may be responsible for the phenomena known as foxfire and perhaps will o' the wisp.
As a forest pathogen, Armillaria can be very destructive. It is responsible for the "white rot" root disease (see below) of forests and is distinguished from Tricholoma (mycorrhizal) by this parasitic nature. Its high destructiveness comes from the fact that, unlike most parasites, it doesn't need to moderate its growth in order to avoid killing its host, since it will continue to thrive on the dead material.
Bioluminescent Honey fungusAmong European rural people, especially in Gaelic, Slavic and Germanic folk cultures, the Will-o'-the-wisps are held to be mischievous spirits of the dead or other supernatural beings attempting to lead travellers astray (compare Puck). Sometimes they are believed to be the spirits of unbaptized or stillborn children, flitting between heaven and hell. Other names are Jack O' Lantern, or Joan of the Wad, Jenny Burn-tail, Kitty wi' the Whisp, or Spunkie.
Anybody seeing this phenomena might merely have been seeing, without knowing, a luminescing Barn Owl, at least in some instances. As strange as it may seem, much anecdotal evidence supports the fact that Barn Owls have a luminescence which may be due to fungal bioluminescence (Honey fungus) or some other cause.


My two cents.....the guy gets another chance. Hopefully he's motivated to use his god given ability and reaches his potential. If he's does ...he's a tremendous asset on the cheap. If he can't do it....then cut him. No one really knows what's going to happen.....but there is a big ray of hope at the end of the tunnel. I gotta pull for the kid.
Good points. Haha justin zimmer, shede should be fine.
That's vehicular homicide and is not a midemeanor. Far more people die in non-intoxicated accidents.
Not on "your sack", just asking a question. You seem to be upset at the 2-3 out of 25 who were excited by the signing. Actually willing to bet that all the over the top guys were all joking and you're literally posting about something that doesn't exist. The overwhelming vibe from this thread is, good signing, go prove it, not OMG SHEDE'S BACK, SUPER BOWL!
Why arent we doing his whole tenure and just his last 6? Why don't we do his last 4? 36-27. 3-2 in the playoffs. 1 Superbowl appearance. TD is the best Falcons GM ever and it isn't close.
Thanks for the read but not really a fan of this draft or giving up our 2nd round pick next year. As you mentioned CB is basically the only position we didn't address so far this free agency and you helped us zero in a position where we need 1-2 extra. I'd grab Burns in your scenario and look for a couple of additional 2nd round picks instead where we can grab prospects like OT Howard and CB Bunting.
Hageman must have matured tremendously over the past couple years. I'd imagine he's been humbled. I'm all for giving him another shot if his head is on straight this time.
I think he will be just fine. I am wondering what is going to happen come draft time now. Jarrett hasn't signed his franchise tag and I am starting to think we are going to lose Jarrett and get 2 first round picks. I think the Compensation would be future first round picks? I don't know how it works. With the draft coming, Jarrett on a franchise tag he hasn't signed yet nor a contract has been made, I am starting to believe another team will come in and try to sign Jarrett to a huge deal. This could be the Raiders. I would not be shocked we play this season with out the likes of Trufant and Jarrett. I think the Falcons will keep Julio and give him the contract he deserves. I am looking at the Raiders as a possible landing spot for Trufant and Jarrett in some kind of trade. Raiders have NO corners nor defensive tackles.


Update: Bridget Rooney is the winner of the random drawing for the two pairs of free tickets.
20at20 runs through September 22nd.
Ticket Giveaway: Win tickets to any two shows on the list of 20at20.
To promote the program, I'm offering the winner of this contest TWO pairs of tickets. Pick any two shows from the list below.
But you must answer the question fully, or your entry will not be approved for submission.
3. This contest ends Wednesday, September 11, 2013 at midnight Eastern Time, and I will make the drawing no later than noon the next day. You must respond to my direct message on Twitter within 24 hours or I will choose another winner.
You must also be in New York able to attend one of the eligible performances.
Bayside! The Saved By The Bell Musical!
I would like to see Women or Nothing – I love the Coen brothers and have heard very positive reviews of this production! I also want to see Peter and the Starcatcher. I've always been interested in seeing this, since it first appeared off broadway, then on broadway, now off broadway again, but somehow never got around to it – this time I will! I love the Peter Pan story. My mother told me she saw Peter Pan starring Mary Martin when she was pregnant with me!.
I would love to see Avenue Q because it's hilarious and I'm going through a Princeton phase right now getting out of college. Additionally, I love Peter and the Starcatcher. The show never fails to make me laugh but also gives me an inspiring feeling.
I would live to Bayside and iLuminate because interesting and innovative theatre needs to be supported!
I would like to see Unbroken Circle and iLuminate: Artist of Light. Unbroken Circles makes me think of all the family secrets that exist in my family. Right now the "Godmother" of the family is very sick. I would hope for a death bed confession but I think she is taking one very Big Family secret to the grave.
I would love to see Tennessee Williams' The Two Character Play. I'm a huge fan of Tennessee Williams and have loved all of his work I've read. I would also love to see Women or Nothing. The storyline seems interesting and I am interested to see Ethan Cohen's work as a playwright.
Would love to see Bayside! as I simly LOVE Saved by the Bell, even though I saw it in syndication, Soemthing I did see was Peter and the Starcatcher, but would love to see it again in a more intimate space as I felt the show was best written that way.


text:
US-Iran tensions to escalate with UN vote
Iranian President Hassan Rouhani and US President Donald Trump. REUTERS.
President Donald Trump's administration will force a vote this week to extend the UN arms embargo on Iran, likely leading to the final unraveling of the deal the country struck with world powers in 2015 to scale back its nuclear program. With Trump's odds of winning reelection in November sinking, US hawks are trying to escalate pressure against Iran to tie the hands of Democratic challenger Joe Biden, who would likely resume diplomatic outreach to the US's long-time foe. The coming months will be fraught with risk.
The UN vote
As part of the nuclear agreement, world powers and Iran agreed that the UN arms embargo would expire in October 2020. The Trump administration, which withdrew from the deal in 2018, opposes the expiration of the embargo and has warned that Iran would go on an international arms buying spree. The evidence for this concern is mixed, especially in the near term: facing an economic crisis, Iran has limited financial capacity to order big-ticket weapons, and Russia and China, the most likely exporters, face political constraints. Nevertheless, the US has drafted a hardline resolution to extend the embargo indefinitely. Washington's campaign has fallen on deaf ears. Russia and China, which hold vetoes in the Security Council, will almost certainly block the proposal. It's possible that the veto will not even be necessary, as the resolution may not earn the requisite nine votes in favor. That would be a particularly vivid demonstration of the Trump administration's isolation on the Iran issue.
Disputed snapback
The US has threatened that if it doesn't get its way on the arms embargo extension, it will trigger the return of all UN sanctions on Iran and formally scrub the nuclear agreement from the books. Indeed, for US hawks, the arms embargo issue is merely a pretext to accomplish this larger goal. The architects of the nuclear agreement put in a provision allowing the US—or any other Security Council permanent member—to unilaterally annul the agreement if Iran committed "significant nonperformance." Washington claims that it can trigger snapback even though it publicly withdrew from the deal. Diplomats in Russia, China, and Europe reject this logic. The fight in the Security Council will likely end with uncertainty about the status of snapback: the US will argue it happened while Russia and China will say it didn't. And that will leave Iran with a significant choice about how to respond.
For US hardliners, the urgency of killing the agreement is closely linked to the increasing likelihood of a Biden presidency. The Trump administration has taken a number of steps to make it more difficult for a future president to re-enter the nuclear deal or something like it, such as by creating duplicative layers of sanctions to make them more difficult to remove. Triggering snapback would be the icing on the cake. None of this precludes Biden from re-entering the deal. It just makes it more politically complicated, especially if Iran responds to snapback by taking more aggressive nuclear steps, moving farther away from the nuclear deal's limits and closer to a weapons capability.
Heightened risk in the months ahead
Tehran is facing an increasingly challenging domestic and international environment. US sanctions have significantly weakened its economy, and the coronavirus pandemic has killed thousands and further undermined public trust in government. A key facility at the Natanz nuclear site was destroyed early last month, apparently in an Israeli sabotage effort. Tehran has largely acted with restraint, on the assumption that Biden is likely to win and that a conflict before then could benefit Trump. But Tehran's restraint is not open-ended. Tehran will likely be forced to respond to the snapback in the coming months, such as by formally withdrawing from the agreement itself or curtailing international inspections of its nuclear facilities.
Beyond snapback and the nuclear issue, there are additional risks this fall. The US or Israel could escalate in other ways, on the assumption that it would be a "win win"—either Iran does not respond, and the action is "cost-free," or it does respond and further isolates itself. This is a risky assumption, as Iran is skilled at threading the needle and conducting attacks in ways that cannot be traced back to it. US or Israeli action could include additional cyber operations, sabotage at nuclear facilities, or potentially seizing Iranian ships at sea. That means more risk in US-Iran relations as the US election approaches.
U.S. runs up against its debt limit, so Treasury starts using 'extraordinary measures': here's what it means
Jon Lieber
Analysis by Jon Lieber and Kylie Milliken
Iran sends first shipment of drones to Russia for use in Ukraine
Cliff Kupchan
Analysis by Clifford Kupchan
Swirling doubts herald major shifts at upcoming Chinese political meeting
Neil Thomas
Analysis by Neil Thomas

redpajama_set_name: RedPajamaCommonCrawl


The Treasury Departments Financial Crimes Enforcement Network has issued a rule proposal that would require investment advisers to establish anti-money laundering programs and report suspicious activity, as required by the Bank Secrecy Act.
The BSA does not expressly include "investment adviser" among its list of entities defined as a financial institution. FinCEN, with the proposed rule announced on Tuesday, would add investment advisers to that definition, subjecting them to similar regulations that already apply to mutual funds, broker-dealers, banks, and insurance companies. Among those requirements are filing Currency Transaction Reports and maintaining records relating to the transmittal of funds.


text:
Molecular subtypes of ALS are associated with differences in patient prognosis
NYGC ALS Consortium
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood clinical heterogeneity, underscored by significant differences in patient age at onset, symptom progression, therapeutic response, disease duration, and comorbidity presentation. We perform a patient stratification analysis to better understand the variability in ALS pathology, utilizing postmortem frontal and motor cortex transcriptomes derived from 208 patients. Building on the emerging role of transposable element (TE) expression in ALS, we consider locus-specific TEs as distinct molecular features during stratification. Here, we identify three unique molecular subtypes in this ALS cohort, with significant differences in patient survival. These results suggest independent disease mechanisms drive some of the clinical heterogeneity in ALS.
Dive into the research topics of 'Molecular subtypes of ALS are associated with differences in patient prognosis'. Together they form a unique fingerprint.
prognosis Physics & Astronomy 100%
Amyotrophic Lateral Sclerosis Medicine & Life Sciences 73%
Heterogeneity Chemical Compounds 63%
Specific Locus Chemical Compounds 56%
stratification Physics & Astronomy 39%
pathology Physics & Astronomy 20%
cortexes Physics & Astronomy 19%
progressions Physics & Astronomy 19%
NYGC ALS Consortium (2023). Molecular subtypes of ALS are associated with differences in patient prognosis. Nature communications, 14(1), [95]. https://doi.org/10.1038/s41467-022-35494-w
Molecular subtypes of ALS are associated with differences in patient prognosis. / NYGC ALS Consortium.
In: Nature communications, Vol. 14, No. 1, 95, 12.2023.
NYGC ALS Consortium 2023, 'Molecular subtypes of ALS are associated with differences in patient prognosis', Nature communications, vol. 14, no. 1, 95. https://doi.org/10.1038/s41467-022-35494-w
NYGC ALS Consortium. Molecular subtypes of ALS are associated with differences in patient prognosis. Nature communications. 2023 Dec;14(1):95. doi: 10.1038/s41467-022-35494-w
NYGC ALS Consortium. / Molecular subtypes of ALS are associated with differences in patient prognosis. In: Nature communications. 2023 ; Vol. 14, No. 1.
@article{df83175e969d4624a45371118c0cb233,
title = "Molecular subtypes of ALS are associated with differences in patient prognosis",
abstract = "Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood clinical heterogeneity, underscored by significant differences in patient age at onset, symptom progression, therapeutic response, disease duration, and comorbidity presentation. We perform a patient stratification analysis to better understand the variability in ALS pathology, utilizing postmortem frontal and motor cortex transcriptomes derived from 208 patients. Building on the emerging role of transposable element (TE) expression in ALS, we consider locus-specific TEs as distinct molecular features during stratification. Here, we identify three unique molecular subtypes in this ALS cohort, with significant differences in patient survival. These results suggest independent disease mechanisms drive some of the clinical heterogeneity in ALS.",
author = "{NYGC ALS Consortium} and Jarrett Eshima and O{\textquoteright}Connor, {Samantha A.} and Ethan Marschall and Robert Bowser and Plaisier, {Christopher L.} and Barbara Smith",
note = "Funding Information: The authors would like to acknowledge The Target ALS Human Postmortem Tissue Core, New York Genome Center for Genomics of Neurogenerative Disease, Amyotrophic Lateral Sclerosis Association, Tow Foundation, and the patients and family members for supporting this analysis. The authors would like to acknowledge Solo Pyon for his assistance with the high-speed download of patient sequencing data from the European Bioinformatics Institute data repository (NCBI mirror). The authors thank Paula Phan for her assistance with vector-based figure preparation. The authors would like to thank Oliver. H Tam and Molly G. Hammell for their correspondence regarding unsupervised clustering. The authors would also like to thank Yu-Jui Ho for his assistance with SAKE usage and installation. All NYGC ALS Consortium activities are supported by the ALS Association (ALSA, 19-SI-459) and the Tow Foundation. J.E. is supported by the National Science Foundation, Graduate Research Fellowship (026257-001). Publisher Copyright: {\textcopyright} 2023, The Author(s).",
T1 - Molecular subtypes of ALS are associated with differences in patient prognosis
AU - NYGC ALS Consortium
AU - Eshima, Jarrett
AU - O'Connor, Samantha A.
AU - Marschall, Ethan
AU - Bowser, Robert
AU - Plaisier, Christopher L.
AU - Smith, Barbara
N1 - Funding Information: The authors would like to acknowledge The Target ALS Human Postmortem Tissue Core, New York Genome Center for Genomics of Neurogenerative Disease, Amyotrophic Lateral Sclerosis Association, Tow Foundation, and the patients and family members for supporting this analysis. The authors would like to acknowledge Solo Pyon for his assistance with the high-speed download of patient sequencing data from the European Bioinformatics Institute data repository (NCBI mirror). The authors thank Paula Phan for her assistance with vector-based figure preparation. The authors would like to thank Oliver. H Tam and Molly G. Hammell for their correspondence regarding unsupervised clustering. The authors would also like to thank Yu-Jui Ho for his assistance with SAKE usage and installation. All NYGC ALS Consortium activities are supported by the ALS Association (ALSA, 19-SI-459) and the Tow Foundation. J.E. is supported by the National Science Foundation, Graduate Research Fellowship (026257-001). Publisher Copyright: © 2023, The Author(s).
N2 - Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood clinical heterogeneity, underscored by significant differences in patient age at onset, symptom progression, therapeutic response, disease duration, and comorbidity presentation. We perform a patient stratification analysis to better understand the variability in ALS pathology, utilizing postmortem frontal and motor cortex transcriptomes derived from 208 patients. Building on the emerging role of transposable element (TE) expression in ALS, we consider locus-specific TEs as distinct molecular features during stratification. Here, we identify three unique molecular subtypes in this ALS cohort, with significant differences in patient survival. These results suggest independent disease mechanisms drive some of the clinical heterogeneity in ALS.
AB - Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood clinical heterogeneity, underscored by significant differences in patient age at onset, symptom progression, therapeutic response, disease duration, and comorbidity presentation. We perform a patient stratification analysis to better understand the variability in ALS pathology, utilizing postmortem frontal and motor cortex transcriptomes derived from 208 patients. Building on the emerging role of transposable element (TE) expression in ALS, we consider locus-specific TEs as distinct molecular features during stratification. Here, we identify three unique molecular subtypes in this ALS cohort, with significant differences in patient survival. These results suggest independent disease mechanisms drive some of the clinical heterogeneity in ALS.


k-Space Associates, Inc., a leader in in situ, ex situ and in-line metrology tools for the thin-film, semiconductor, photovoltaic (PV), solar, automotive, glass, and building materials industries, has announced increased annual sales for the kSA 400 product line. They reported an increase of 27% in kSA 400 installations in 2018 for their kSA 400 analytical RHEED (Reflection High-Energy Electron Diffraction) system, compared to 2017.
The kSA 400 analytical RHEED system combines a high-resolution, high-speed, and high-sensitivity camera with sophisticated RHEED-specific acquisition and analysis software. Because of its advanced capabilities, continued new feature enhancements, and proven history of over 25 years, the kSA 400 is the preferred analytical RHEED system worldwide for research and manufacturing.
For more information about k-Space or the kSA 400 analytical RHEED system, please visit www.k-space.com.
k-Space Associates, Inc. (www.k-space.com) is a leading metrology supplier of in-line, in situ, and ex situ metrology tools for the semiconductor, thin-film, photovoltaic (PV), solar, automotive, glass, and building materials industries. Founded in 1992, its systems are used for monitoring dimensions, wafer temperature, thin-film stress, deposition rate, thickness, material absorption properties, and Reflection High Energy Electron Diffraction (RHEED). Backed by a commitment to ongoing support, these solutions are currently used worldwide in research and production line monitoring of multiple industries. Extensive input and close collaboration with its worldwide customer base have led to the development of today's most powerful metrology.


Water and oil do not mix. Scientific experiments demonstrate that water settles beneath the oil and that oil always floats to the top, suffocating the environment below. In nature, oil spills present enormous potential for harm and occur when humans make mistakes, are careless or enact deliberate acts of sabotage. This description of oil and water is a useful metaphor for mixing justice and morality with global politics. It is most disappointing to note, however, that this analogy is particularly apt – water and oil separate themselves when mixed; just as global politics is currently separated from global justice and morality. However, it is in today's complex political environment that the voices of morality and justice need to be heard more than ever.


show to dump the configuration.
The idea is simple: each time a new PostgreSQL version is built, a configuration file is created for such instance. You can then customize the file in order to make pgenv behave differently for that particular version of PostgreSQL. As an example, you can set different languages (e.g., PL/Perl) or different startup/stop modes. If the configuration file for a particular version is not found, a global configuration is loaded. If neither that is found, the program behaves depending on some shell variables or, as last resort, with its internal defaults. Please read the documentation for a better explaination of the new config command.


text:
Dr. Vivek Bindra's YouTube channel becomes number one globally
Dr. Vivek Bindra's channel becomes number one in Entrepreneurship across the globe. Each day new content creator is launching their Youtube channel and striving their way towards success and new content. Most of the content available for the viewers today is all about entertainment and comedy. However, there are a few people who are using their influence and reach to spread awareness or learnings.
Such popular channels include Technical Guruji which is famous for its original content for the tech geeks and another such is Dr. Vivek Bindra's channel which has now crossed the milestone of 10 million + subscribers just in less than a year and has become the world's most subscribed channel in entrepreneurship. Other such channels that aren't even in the proximity are the New York Times (1.8 MN), Al Jazeera (3.3 MN), BBC (4.4 MN) & Harvard Business Review (200,629).
Dr. Bindra's channel gives free coaching lessons to their viewers and helps them solve the burning problem of their business. He currently has over 570 million + viewership coming back to his channel to view the content he shares. Dr. Bindra who apart from being an international motivational speaker, is also the founder & CEO of BadaBusiness has left no stones unturned in promoting entrepreneurship to all age groups and gender.
The content on his channel is very well researched and then made into a video for the masses to understand and implement quickly, his content which is available in Hindi is for the sole purpose for him to reach the people with a business dreams in every part of the country. Dr. Bindra said, "My content is made for the people of my country, I aim to help my country grow and make the individuals independent."
Dr. Vivek Bindra had started with 3 people in his team and now has 300+ plus employees, he has changed the meaning of OTT by using it to educate people. His channel also has a massive following in Pakistan, Nepal, Oman, UAE, UK, and the USA.
In a statement, he said, "I will keep going until I have reached and helped every individual I can to be a business owner."
Kartik, Bhumi, Ananya Relive The 90s Era With 'Ankhiyon Se Goli Maare'
Kartik Aaryan, Bhumi Pedenkar and Ananya Panday starrer Pati Patni Aur Woh is making the headlines for all the right reasons and has become the talk of the town. Last week, after dropping their first song Dheeme Dheeme, which has gone viral on the internet and several lip-sync apps and even netizens taking the dance challenge using the hashtag #DanceLikeChintuTyagi, the makers of Pati Patni Aur Woh are all set to release their second song. The team has recreated '90s hit number, Ankhiyon Se Goli Maare and are all set to release it today. Kartik is specially flying down to Delhi from Patiala to launch the party number with his leading ladies, Bhumi and Ananya.
Stepping into dancing shoes of Govinda and Raveena Tandon, Ankhiyon Se Goli Maare will see Kartik shaking a leg with his 'Patni' Bhumi and 'Woh' Ananya. The actor's moves in Dheeme Dheeme has made the internet go crazy and looks like the trio is going to teach us few more signature steps this party season. Choreographed by Farah Khan, this song is a perfect tribute to the evergreen superstars and Kartik-Bhumi-Ananya have done some steps and antics will make this one an instant hit. The recreated song is a peppy dance track and it will relate with today's youth. The vibe and tone of the song is also very colourful and vibrant, it promises to be another blockbuster for the team. People who have seen the rushes of the song say that Kartik's chemistry with both his lead actresses is something to look forward to. This song will definitely keep everyone hooked as the old version still has a high recall value.
Producer Bhushan Kumar (T-Series) says, "Ankhiyon Se Goli Maare is my personal favourite from the album. Since it has the 90s magic with a modern twist, the song brings back lots of memories. The trio - Kartik, Ananya & Bhumi have done complete justice in this one. We hope the audiences love the modern version too."
Creative producer Juno Chopra (BR Studios) says, "Ankhiyon Se Goli Maare was the last leg of shoot and the entire team had whale of a time while shooting for it. Kartik, Ananya, Bhumi & Farah enjoyed to the fullest on the sets. Farah comes up with such funny situations that while shooting we were continuously in splits. We hope that just like our first song received all the love, this one too garners lots of love and appreciation."
Farah Khan says, "Ankhiyon Se Goli Maare is an iconic song and I agreed to do it because Juno is a dear friend. Hope this new foot tapping version appeal to the audience the way the original song did back then. We have tried to make it different and interesting but at the same keeping the essence of the original intact."
Talking about same actor Kartik Aaryan says, "This song used to be one of my favourite Govinda sir's track during my growing up years. We all have been an ardent admirer of his dancing style. I'm so happy that I got an opportunity to dance to it in my film. Also, I always wanted to dance on Farah mam's tunes and glad that here my that wish also got fulfilled. She has given some cool and fun moves to all of us. Ananya, Bhumi and I had blast shooting for it."
Singer Tulsi Kumar says, "We have all grown up listening to these peppy numbers which just remind you of so many things and memories. I have grown up to the 90's music n getting an opportunity be a part of this iconic Govinda - Raveena Tandon number Is a dream come true. I have added some contemporary touch to this song which has been musically modulated by Tanishq Bagchi to make it more relatable to the new generation. But of course, the essence remains the same . You all are up for a musical treat with this party number."
Sung by Mika Singh & Tulsi Kumar and composed by Tanishk Bagchi, Ankhiyon Se Goli Maare is all set to become the biggest party song of the year and we're ready with our dancing shoes.
Labels: Song
म्यूजिक विडियो Yaara में Rajniesh Duggall और Nataliya Kozhenova
Sony MAX presents the World Television Premiere of Khandaani Shafakhana
Sony MAX presents 'Khandaani Shafakhana' as its World Television Premiere this November. The film starring Sonakshi Sinha, Varun Sharma and popular singer Badshah will help break the taboo around the topic of fertility clinics in small town India. The film will premiere on 22nd November 2019 at 8PM only on Sony MAX.
Produced by T-Series and Sundial Productions and directed by Shilpi Dasgupta, Khandaani Shafakhana is the story of a woman, receiving the ownership to her uncle's fertility clinic. Despite the social pressures she faces to repurpose the clinic into a business venture more befitting of a young woman, Babita 'Baby' Bedi (Sonakshi Sinha) takes on the business with a firm outlook on making it prosper and breaking the taboo around it with the help of Gabru Ghataak (Badshah). Playing the fool, her brother, Bhooshit Bedi (Varun Sharma) adds his quirky remarks along the way to get the kind of popularity his sister now enjoys.
Speaking a bit about preparing for the role and getting close to his co-stars, Badshah adds, "I had been reading a couple of scripts at the time. Sonakshi has played a very important role in the decision making. She read the script first and immediately had recommended my name. And when I spoke to her, she just made me go for it. They were also extremely patient with me in pulling up the correct shot. Honestly, I did not have to prepare much for the role. I had a certain image of Gabru in my mind from the moment I heard the script and I was just going with the flow. I definitely have a lot of new found respect for film makers and actors after this experience though. I think the whole process was a lot of fun."
Speaking about his experience shooting for the film, Varun Sharma reminisces about his experience on why he chose the film, "I was really thrilled when I received this opportunity, because it was interesting as a film and had a very important message and it was about breaking certain taboos. So, I instantly jumped on to it and I wanted to be a part of it. The experience working with Badshah and Sonakshi was fantastic – we connected over music and other conversations, we have become thick friends now. Every day was a lot of fun, one of the tastiest incidents was going to Amritsar for Amritsari Chole and while talking about it now, I recall the taste of it."
Catch Khandaani Shafakhana only on Sony MAX on 22nd November 2019 at 8pm
Labels: Sony MAX, World Premier
Anil Kapoor bags "Icon Of Wellness" at the Globalspa Fit & Fab Show 2019
Anil Kapoor was honoured as the "Icon Of Wellness" at Globalspa Fit & Fab Awards, 2019. With a glorious career spanning four decades, the evergreen actor continues to be a gamechanger.
True to his experimental streak, Kapoor has explored untapped genres and spared no effort to ace his act. It is no coincidence that the actor continues to be relevant today; it is the result of constant reinvention on his part. In the 40th year of his career, Kapoor invariably gives the younger generation of actors a run for their money with his infectious energy.
Recognising the actor's passion for his craft, GlobalSpa Fit & Fab Show felicitated the actor for his professional achievements as well as his personal conduct towards fitness. The energetic actor was also hailed as a fitness inspiration for the country.
Bella and Vienna's Halloween themed birthday bash was an absolute hit
Actor Karanvir Bohra and wife Teejay Sidhu threw one of the cutest and fanciest halloween themed birthday parties for their twin daughters Bella and Vienna!
The girls who are quite an internet sensation better known as 'twin baby diaries' on social media, had a very different birthday party this year which was an interactive and fun filled one with various activities like face painting, tatoo drawing, a life sized trampoline to jump on among other stuff to do for the children!
Bella and Vienna had 3 very special cake cuttings throughout the course of the party. One with all their close friends and family, one with their friends from the media and one with actor Ashish Choudhary's twin girls who also celebrated their birthday today!
Living up to the theme of the halloween birthday party, Bella and Vienna were dressed as twin Rapunzels, and Teejay was Elsa from Frozen while Karanvir was dressed as Prince Charming. A lot of the other children came dressed as different characters too like Batman, Superman, Mickey Mouse etc!
While the twins 3rd birthday party was filled with close family and friends, a lot of Karanvir and Teejay's friends from the industry along with their children were seen having a blast at the kiddie party! Krushna Abhishek, Karan Mehra and wife Nisha Rawal, Karanvir's Quobool Hai costar Amarpali, Raghu and Rajeev, Naagin actress Adaa Khan, Vikas Kalantri, Jay Bhanushali and Mahhi Vij, Rajneesh Duggal, RJ Hrishi K and Sidharth Kanan, Chahat Khanna, Tarun Katiyal, Producer Ajay Chopra among many more from the industry were part of this fun celebration!
Labels: news event
Feryna Wazheir sends out a cool message on Diwali
Spunky actress Feryna Wazheir who was seen in Airlift with Akshay Kumar, celebrated Diwali with diyas, sweets and looked stunning in a traditional saree, replete with jumkaas and kajraas. Most importantly, the hep-turned-desi-gal had a cool message.
"Diwali is the festival of lights. So it should always be celebrated by lighting oil lamps, bonding with friends and family, and spending a good time with a positive outlook for the year to come," says Feryna and adds, "the lesser the noise pollution, the better."
Her subtle message is taken. Cheers, Feryna. Here's to your happiness and to the world. Like minds would surely make this world a better place for you and for me and the entire human race.
Feryna will soon be seen in a key role in Commando 3 along with Vidyut Jammwal and Adah Sharma, Angira Dhar and Gulshan Devaiah.


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Q: Force case-sensitive routing in ASP.NET MVC This question has been asked in a similar but not identical fashion (and not resolved to my satisfaction) previously on Stack Overflow and elsewhere.
Coming from a linux-world, I want to use ASP.NET MVC but avoid identical but differently-cased routes from resolving to the same page. I do not want to force all routes to be 100% lowercase.
e.g. I want /Home/Something to be a valid route and /Home/somethingElse to also be a valid route, but not /Home/something or /home/somethingelse, given two functions called Something and somethingElse in the HomeController.
I can't find any way of doing this from within the RegisterRoutes function, but maybe I'm missing something obvious? I can answer this easily enough by adding code to each Controller function, but I'm obviously trying to avoid doing that.
Optimally, the solution would involve catching all permutations of a particular route, then 301 redirecting any that do not exactly match the case of the controller's function.

A: I was unable to find any way of doing this after extensive searching. Basically, case-sensitivity and IIS/ASP.NET apparently do not go together.
We're now using a bit of a kludge to solve this. The code has been opensourced (MIT license) on github: NeoSmart Web Toolkit, in particular, this file containing the SEO redirect code.
Using it is easy enough: each GET method in the controller classes needs to add just this one line at the start:
Seo.SeoRedirect(this);

The SEO rewrite class automatically uses C# 5.0's Caller Info attributes to do the heavy lifting, making the code above strictly copy-and-paste.
Ideally, I would love to find a way to turn that line of code into an attribute. For instance, prefixing the controller methods with [CaseSensitive] would automatically have the same effect as writing in that line, but alas, I do not (yet) know how to do this.
I also can't find any way of figuring this out with the Routing class/structures. That's some opaque code!

redpajama_set_name: RedPajamaStackExchange


There are more than 30 scientists and other professionals engaged in research pertaining to the natural wealth of Pakistan.
PMNH scientists/researchers collect, preserve, label and catalogue natural history specimens (plants, animals, rocks, minerals and fossils) as a reference material according to the standardized procedure.
PMNH scientists contribute towards discovery of new species of animals, fossils and plants.
PMNH scientists publish research outcomes in the national and international journals.
PMNH collaborates with various R&D and academic organizations of foreign countries such as China, France, Italy, Japan, Poland, Switzerland, Tajikistan, UK and USA for research activities.
PMNH displays the natural history of Pakistan through 3-D dioramas, galleries and various exhibits.
PMNH regularly publishs the natural history brochures, leaflets, bulletins, books and posters for mass education.
PMNH organizes symposia/workshops/conferences related to the natural history issues on regular basis. Celebration of different international days is a regular feature of PMNH activities.
PMNH facilitates in setting-up the new museums. Establishment of National Museum of Science and Technology Lahore, Maritime Museum Karachi, Children Complex Lahore and Science Center Faisalabad are some of the examples on its credit.
PMNH offers scientific experties on Geological, Botanical and Zoological expeditions, exploration, collection, preservation and curation as well as taxidermy and model preparation.
Provides services in the identification of plants, animals, minerals, rocks, fossils, precious and semi-precious stones.
Provides technical assistance in the establishment of new museums/natural history corners and organizing large scale scientific exhibitions and expos.
Provides services of popular scientific lectures / films shows to schools, colleges and universities etc.


Another wonderful Black Walnut Slab with a wonderful translucent burl that will make an elegant Coffee Table or perfect as a Console.
These Single Planks illustrate the wide range of available slab choices for Console Tables, Coffee Tables, and smaller pieces. The options are endless.
It would make a stunning folded leg piece. It has great visual surface interest with a substantial width, and a lovely natural edge.
This beautiful slab is currently unfinished. It will glow with a deep luster after final sanding and polishing.


Our two luxury cabins, Tynant and Tyncoed, are nestled deep in the Welsh countryside - in the bottom meadow on Cwmachau Farm, just north of the Brecon Beacons.
Take in the stunning views of the Honddu Valley from your cabin's veranda, unwind in the hot tub or take a walk around our working sheep farm to soak up the scenery.
Whether you're after an active break, or just some time away from it all, your hosts Chris and Jackie Davies are full of local knowledge and will do all they can to make your stay enjoyable.
Our cabins are perfect for couples or a small family, sleeping 2-4 in a double bed and sofa bed. Each is equipped with a small but perfectly formed fitted kitchen (complete with oven, hob, microwave and fridge), shower room, dining area, sofa and TV.
French doors lead to a veranda with table and chairs, where you can sit and soak up that view on warm summer evenings. Each cabin has its own electric hot tub just outside, lie back in the bubbles and watch the sheep grazing on the hills and the river snaking its way down the Honddu valley below.
There are many beautiful walks around the farm and beyond, taking in stunning views of the Brecon Beacons, Black Mountains and Epynt hills.
Situated half way between the pretty towns of Brecon and Builth Wells you won't be short of things to do and places to explore, with events such as the Hay Festival of Literature and the Arts, Brecon Jazz, Abergavenny Food Festival, Welsh Lavender Farm and the Royal Welsh Agricultural Show right on your doorstep.
Peak season: £444.00/week. Short stays from £283.00/2 nights.
Low season: £323.00/week. Short stays from £226.00/2 nights.
Directions: From Lower Chapel on the B4520, continue for one mile passing through Catle Madoc. Turn left at the first by road junction (half a mile out of Castle Madoc) and follow the lane up. Turn right where you see the sign for Cwmachau Cabins.
Booking your stay with us is easy. Simply check the availability calendar on the left, and then phone us on 01874 690342 to confirm your booking. Alternatively, complete the booking enquiry form below and we will get in touch to confirm your dates.


Mobile 3D back covers are the best attractive accessory to make your mobile phone unique from other models .This CaseLite Matte Finishing case is made out of a light, durable plastic called Polycarbonate. It is flexible enough to snap on to your phone with ease and strong enough to protect it from bumps, drops and scratches. The raised lip on the sides of the case also protects your phone's screen. It is the newest trend in the mobile phone accessories for the dual purpose of personalization and protection as well. CaseLite 3D Back case offers you wide ranges of back cover. CaseLite Matte Finishing Back case Printing Technology ensures incomparably high print quality and extra oridinary level of detail. Our catalog includes the wide array of designs and models. CaseLite Designer covers 100% of the outer surface of the case is precision moulded with no seams or sharp edges No peeling,chipping or wearing off. The design on this perfectly finished .The Precision cutouts on this case leave all buttons, ports, speakers and microphones completely open. This case is 100% compatible with your regular charger and headphones.


As the cybersecurity industry adopts artificial intelligence techniques in earnest, quietly cyber criminals are building their own artificial intelligence adversarial tools. This article explores the likely "first contact" enterprises will face with adversarial AI.
The case for using artificial intelligence to defend networks against attacks grows as legacy security technologies wane in effectiveness against new attacks. As destructive attacks like WannaCry and NotPetya resurrect worm spreading behaviors, the urgency for automated defense has never been higher. Simply stated, we cannot successfully fight an adversary that works at the speed of machines with defenders looking to identify and stop these attacks in human time and scale.
Against this backdrop of increasingly sophisticated threats, new artificial intelligence technology promises to overcome technical challenges with legacy signature-based technologies. For example, we understand that file hash matching works well at detecting known malware, but with most malware attacks not reusing the same file, the signature matching approach has limited utility against detecting current attacks. Machine learning technology such as deep learning algorithms have demonstrated the ability to detect previously unseen malware by training against large volumes of known malware repositories.
While malicious file detection is a problem ripe for machine learning technology, we expect that in the future adversaries will depend less on malware and more on exploiting and leveraging existing legitimate programs on endpoints to do their bidding. This will require a different model of detection -- one based on identifying patterns of misuse of system resources rather than malicious program patterns. Seeing unusual patterns in large volumes of data is where machine learning excels compared to humans who can intuit well, but not in large scale nor at machine time speeds.
Not surprisingly, adversaries are developing their own artificial intelligence techniques.
Adversarial artificial intelligence is often used in two scenarios: (1) gaming defensive AI techniques to find and exploit their weaknesses or blind spots, or (2) using AI for offensive cyber operations. In this article, the focus is on using AI for offensive cyber operations. Having said that, developers of defensive AI solutions need to be especially cognizant of failure modes in their approaches such as catastrophic failures due to homogeneous training sets, or simply the law of large numbers that states many pedestrian attacks will get past machine learning approaches because most are simply statistical estimators of a function, not a hard and fast rule.
Cyber adversaries already automate several stages of attack, including target discovery and malware generation and deployment. These developments have made defending against attacks more challenging for legacy security systems. However, artificial intelligence now gives adversaries new tools to automate even more parts of the adversary TTPs (tactics, techniques, protocols).
Academic studies have shown that you can achieve higher click through rates on phishing emails and tweets using machine learning algorithms over human-generated phishing campaigns. This should not be surprising given the advances in chat bots in dealing with human queries. From an adversarial perspective, why take the time and effort to handcraft a phishing campaign when a machine learning algorithm can do it better, cheaper, and in larger volumes? Traditional means of phishing detection training for humans will likely fail in even higher rates in noticing machine generated phishing campaigns simply because they often look for human errors.
Detecting vulnerabilities in programs, the grist for the 0-day vulnerability mill, is ripe for advances in machine learning. Automatic fuzzing tools such as AFL have enabled smarter feedback-based fuzzing using results from prior fuzzing runs in brute force manner. Automated fuzzing has already resulted in the discovery of a number of critical 0-days. Applying AI algorithms to crash dump logs can be used to optimize the generation of better fuzz test cases that can induce exploit rich crashes. While software vendors could use this to find vulnerabilities in their software before releasing, adversaries are motivated by finding and exploiting 0-days. This is not hypothetical -- it is a key strategy for advanced nation states in finding and exploiting 0-day exploits in target networks.
Zero-days are useful only if they can be exploited. One area that is promising for automation is the development of exploits for heap-based overflows and underflows. Traditionally the process of developing an exploit for a memory allocation vulnerability requires tedious manual work in positioning exploit code relative to the memory stack. A recent talk by Sean Heelan at BlackHat EU demonstrates advances in algorithms that automate this in black-box fashion, which in production, can lead to automatic exploit generation from vulnerability discovery.
Finding zero-days is not the only way to compromise systems of course. When it comes to embedded systems and IoT type devices, failure modes and effects from adversarial actions are not well understood and almost never designed for maliciousness. The single fault hypothesis is used in the design and simulation for most embedded and safety critical systems. Simultaneous failures in different components, like those caused by attacks are not usually modeled and there is little contingency planned for these adversarial scenarios. Analysis of fault trees with automated reasoning can identify optimal points of a system to attack simultaneously, for instance to create a failure mode while masking it to operators and sensors. Expect these techniques to be used in self-driving cars, industrial control systems, and plants by capable and motivated adversaries.
Finally, the stages of attack associated with adversary TTPs, often called the cyber killchain, is a repeatable workflow where the variance is due to particular individual target networks. This workflow is ripe for discovery and automation, similar to how a robot AI completes tasks while overcoming obstacles. The payoff for automating adversary TTPs from exploit to discovery, privilege escalation, data capture and exfiltration is scalable hacking in machine time.
While adversaries are still in early stages of employing artificial intelligence, the profit motive and scalability of AI makes it likely that adversaries will leap ahead of defenders in terms of developing and employing AI for their purposes.
If anything, this means that defenders will have to move even faster to automate defenses that operate at machine speed in order to counter offensive AI algorithms. In other words, expect future battles to be AI on AI where the teams that develop the best AI algorithms with the best training sets wins.
While adversarial AI may sound increasingly discouraging for defenders, the challenge is not hopeless. Machine learning algorithms today are being incorporated in products to detect unknown malware. Artificial intelligence algorithms adversaries are using to find exploitable software vulnerabilities can be employed by software vendors to get in front of adversaries by finding and fixing vulnerabilities in their products before releasing them. Likewise, adversary TTPs are fairly regular. By observing, collecting, and analyzing data, one can detect attack patterns across large data sets and devices using AI algorithms.
The most important takeaway for defenders is that if you are not already down the path of developing or incorporating AI in your defenses, then you are falling behind adversaries. The strategic advantages in scaling and cost mean adversaries will be adopting AI for their purposes. We need to be thinking similarly on the defensive side.


At Edgar Brandt Advisory, we put the strongest emphasis on work as a team effort. Consistently delivering at the highest professional standards requires sharp minds meeting on substance.
We therefore provide an environment that lets our junior colleagues grow substantially from a client standpoint, and our partners be firmly in touch with substantive engagement issues.
Hires at analyst level typically have two to four years experience with major auditing or consulting firms.
The figure below summarizes the steps and expectations of a career with us.


You should really stick to skim when ordering your favorite java. That's because some of the country's most popular and delicious coffee drinks are padded with major fat and calories. In fact, these coffee drinks are more like dessert gut-bombs than daily infusions of caffeine. For the record, the ever-present Starbucks didn't even crack the top 10 – its worst offender, the Whole Milk Java Chip Frappuccino – caps its calories at 23 per ounce, less than half of the No. 1 worst coffee drink. Read on to see which drinks ranked the highest in calories per ounce.
Don't be fooled by the Sugar-Free Caramelatte XL with Half & Half. The 20-ounce version contains 868 calories (43.4 per ounce), 465 calories from fat and 39 grams of sugar. A better choice? The fat-free version. It contains just 388 calories.
Admit it – we all treat ourselves to Mickey D's fries and burgers on rare occasions, and the same should go for some of its coffee drinks. Take the 12-ounce Oreo Frappe: At 45 calories per ounce, it's one McCafe's most caloric drinks, with 68 grams of sugar and 180 calories from fat.
If you order the 20-ounce French Vanilla Caramel Cappuccino Chilla, you'll ingest a whopping 127 grams of sugar, more than five times the amount the average woman should be consuming a day. That's on top of 1,040 calories (52 calories per ounce) and 300 calories from fat.
This beloved doughnut shop earns the two top spots: You can eat two to three doughnuts and get the same amount of calories in the chain's 20-ounce, 1,050-calorie Lotta Latte (tied with the Mocha Dream) drink. At 53 calories per ounce, the Lotta Latte also contains 360 calories from fat and 94 grams of sugar. Opting for the Mocha saves you a scant three grams of sugar, but gets you 10 more calories from fat.
The original article "The 11 Worst Coffee Drinks to Order" appeared on LIVESTRONG.COM.


how do i view my personal checking statements on line,. i can't find the tab/link ?
We're sorry to hear you're having trouble, Christopher, and we'd be glad to help view statements. In order to view your statements online, you will first need to sign in here: http://go.td.com/1eaISlq. Once signed in, you may follow the steps below to view statements: 1. Click on the accounts link at the top of the screen. 2. Click on the checking account number you would like to view statements for. 3. Click on the Statements & Notices tab. 4. Choose the statement period you would like to view and click View Statement. 5. You may then click the print icon if you would like to print a copy of your statement. If you have trouble still, our Banking Specialists would be glad to walk you through the process 24/7 at 888-751-9000. Have a great day, Christopher!