E. coli is commonly used to express recombinant proteins in life science research. However, mammalian cell-based expression systems have several advantages over E. coli, especially for eukaryotic protein expression. Expression in mammalian cells allows for proper protein folding and post-translational modification—features that are key for proper protein function in vitro. pHEK293 Ultra Expression Vectors enable ultra-high, transient overexpression of a protein of interest in human HEK 293 cells. Please visit our tech note for data specific to the use of these vectors for producing monoclonal antibodies.
High levels of recombinant protein expression with pHEK293 Ultra Expression Vectors is accomplished by a transcriptional activation mechanism based on the HIV-1 virus TAR-Tat system. The TAR (transactivation response) element is an RNA sequence derived from HIV-1 that forms a stem loop structure at the 5' end of the viral RNA. Tat is an RNA-binding protein that binds to TAR and promotes transcription.
pHEK293 Ultra Expression Vector I and Vector II systems incorporate the TAR-Tat elements in order to provide ultra-high expression of your protein of interest. Both Vector I and Vector II systems incorporate the TAR sequence in the 5' untranslated region of the target gene, where it will not affect the amino acid sequence of the expressed target protein. For the Vector I system, a Tat cassette is included on the same vector; the Vector II system includes the Tat cassette on a separate Enhancer Vector, enabling greater control of the protein of interest's expression level. With both systems, expression of the Tat protein greatly increases the expression of the protein of interest.
Schematic of protein overexpression using pHEK293 Ultra Expression Vectors. The TAR element forms a stem loop structure at the 5' end of the transcribed RNA. Expression of the Tat element produces the Tat protein which binds to the TAR element in the RNA loop structure. This activates TAR, which in turn promotes high expression of your protein of interest. The cassette in the image above is from the single-vector system, where TAR and Tat are both on the same plasmid as your target gene, enabling more convenient transfection. In the two-vector system, Tat is on a separate plasmid, allowing you to have control over expression levels by varying the ratio of the two vectors.
In order to assess protein expression capabilities, both pHEK293 Ultra Expression Vector systems were used to introduce a fluorescent protein (AcGFP1) into adherent and suspension HEK 293 cells. For comparison, the same assay was conducted with a vector expressing AcGFP1 from a CMV promoter (pBApo-CMV DNA) and a high-expression vector from Company A. Constructs were made by inserting AcGFP1 into the appropriate vectors (details listed in the table at the end of this page).
Higher fluorescence intensity was observed for the pHEK293 systems (conditions 2, 3, and 4) than for either of the other two vectors (conditions 1 and 5). Additionally, a color change in suspension cells was readily apparent to the naked eye for cells transfected with the pHEK293 vectors.
Visualization of AcGFP1 expression in adherent and suspension HEK 293 cells. Adherent cells (experimental conditions 1–5) were cultured in 12-well plates. Suspension cells (experimental conditions 6–10) were cultured in 125-ml flasks. Imaging was done two days post-transfection. Panel A. Fluorescent microscopy images (adherent cells). Panel B. Representative images of suspension cell cultures (condition 7 on the left; condition 10 on the right; images for conditions 6, 8, and 9 not shown, however, quantitative data for all conditions are shown in the figure below). For Panels A and B, experimental conditions are as follows. Conditions 1 and 6: pBApo-CMV; conditions 2 and 7: pHEK293 Ultra Expression Vector I; conditions 3 and 8: pHEK293 Ultra Expression Vector II + Enhancer Vector; conditions 4 and 9: same as 3 and 8, but with a larger amount of Enhancer Vector; conditions 5 and 10: Company A's high-expression vector.
Flow cytometry was used to quantify the expression levels of AcGFP1 in adherent and suspension cells. Cells transfected with pHEK293 Ultra Expression Vector I (conditions 2 and 7) and pHEK293 Ultra Expression Vector II (conditions 3, 4, 8, and 9) displayed fluorescence intensities 5–11 times higher than that obtained with a typical CMV promoter (conditions 1 and 6), and 2–7 times higher than Company A's high-expression vector (conditions 5 and 10). Additionally, cells transfected with the two-vector system displayed an expected increase in AcGFP1 expression when the amount of Enhancer Vector was raised from 0.008 µg (condition 3) to 0.2 µg (condition 4) for adherent cells, and from 0.24 µg (condition 8) to 6 µg (condition 9) for suspension cells.
Flow cytometry analysis of fluorescence intensity of AcGFP1 positive cells. AcGFP1 expression in adherent and suspension cells (transfected with constructs as described above) was quantified two days post-transfection. The table column directly below each bar on the graph lists the amount of each vector used in that specific experimental condition.


Vague sense of unease or being unsettled.
Can't shake a cold, or get several illnesses in a row.
These symptoms make take up to several months to appear, but they are gentle hints that you need to stop and take care of yourself, according to the ADA Center for Professional Success. Your dental practice may be affected if you don't have the energy you need to be at your best.
One easy way to regain control of a stress-filled life is to meditate or do visualization exercises each day. Simply finding a quiet room and unplugging for a few minutes can make a big difference. You can sign up for local meditation classes in your community, or simply take a few minutes each day to refresh, recharge and renew on your own. Benefits can be realized in just a few minutes a day.
Find a quiet room with no distractions.
Reflect on how lucky you are to be working in such a great profession.
Think about a positive patient interaction you had that day.
Other ways to reduce stress include cutting down on caffeine consumption, eating a healthier diet and getting regular exercise.


(1) A registered diving school must keep training records with the minimum details required in accordance with Annexure B for a minimum period of 10 years.
(2) A diving contractor must keep the records contemplated in Annexure B for a minimum period of five years.
(3) If a registered diving school or diving contractor ceases activities, all its records contemplated in this regulation must be handed over or forwarded by registered post to the relevant provincial office.


text:
WHO UNICEF Joint Monitoring Programme
LAST UPDATED : Jan 08, 2017, 02:44 PM IST
Mumbai women's group rallies support to end female genital mutilation by 2030
A blog page of stories and narratives on the Sahiyo website over the last few months has seen a surfeit of voices as diverse as a psychotherapist refusing to recommend khatna and a 24-year old boy from Pakistan on the need for men to start caring; to a Bohra father apologising to his daughter and a grandmother refusing to put her granddaughter through the trauma she had suffered, since a group of Bohra women came forward last year to actively rally against the practice of female genital mutilation cutting (FGMC).
Save forests, save water
World Forestry Day has been celebrated since 1972 as a day to highlight the importance of forests and calling for urgent attention towards the protection and preservation of 'our forest heritage'.
State to launch programme to reduce mortality rate
Jhpiego, a non-profit organization affiliated with the John Hopkins University, USA, will provide assistance to the state government to bring down the infant mortality rate (IMR) and maternal mortality ratio (MMR).
Bihar inches closer to polio eradication
With no case of polio being reported during the last 15 months, i.e. since September, 2010, Bihar has recorded the longest polio-free period.
Intensification of routine immunisation programme set to begin in 38 districts in state
With a message to 'Be wise Immunise', intensification of routine immunisation (IRI) programme is set to begin across 38 districts of Madhya Pradesh.
India-UK joint bid to map malaria, Japanese encephalitis-prone areas
British and Indians scientists have joined hands to predict areas of the country that face the maximum risk of malaria and Japanese encephalitis outbreaks.

redpajama_set_name: RedPajamaCommonCrawl


The visitors that land on your law firm's website can be at very different places in terms of their readiness to convert. Some may simply be performing a bit of initial research, while others may be ready to contact you right away and have you handle their case. In other words, they're at different phases of the client journey.
As a result, it's important that you have a variety of content that caters to each person regardless of where they're at.
Providing the right content that's relevant to the particular phase a prospect is in is critical because giving them the wrong content greatly reduces your chances of making a conversion.
Let's say you've got one visitor—Visitor A. They're vaguely interested in your law firm. Maybe they're just curious about a particular area of law and are looking to learn more. At the moment, they have a very small chance of converting and will require a significant amount of nurturing before they're ready.
And you've got another visitor—Visitor B. They've got a serious case on their hands and are seeking expert legal consultation. If they find the right attorney, they'll contact them right away and have a great chance of converting.
Visitor A would be considered at the top of of the funnel—the awareness stage, and visitor B would be at the bottom of the funnel—the decision stage.
In turn, you would probably want to provide visitor A with some basic educational content that answers questions like "what can I expect during a lawsuit?" or "what's the average personal injury settlement?" Keep mind that you're not trying to convert them right away and simply trying to gain their trust and nurture them along.
But for visitor B, you would want to take a more aggressive approach and provide them with content that's designed to convert. In this case, you would probably want to provide them with more conversion-oriented content and include a call-to-action that directs them to your landing page. You may also want to include testimonials and information on pricing. That sort of thing.
It's important to remember that each visitor is at a different phase of the client journey. Some are just starting out and will take time before they're ready to convert, while others are poised to convert right away and will require very little persuasion. Therefore, you never want to take a one-size-fits-all approach.
Building a sizable content archive that covers all three of these phases can have a dramatic impact. And while it does require a some effort, it should be well worth it in the long run. This way visitors can efficiently make their way through your law firm's sales funnel, which should increase your overall conversion rate.


Suspects arrested for producing and selling illegal homemade alcohol were put on parade by Indonesian police during a public display in South Tangerang, on the outskirts of the Indonesian capital Jakarta, yesterday. Thousands of booze bottles were destroyed by Indonesian police yesterday as they cracked down on bootleg alcohol blamed for killing close to 100 people in recent weeks. The authorities in Tangerang yesterday also drove a yellow steamroller over about 6,000 bottles, while others raided vendors in a bid to stop the worst string of home-brew deaths in years.


text:
40 potholes in just one short stretch of Rasen road
An everyday topic across the whole of the county is the state of the roads - now one councillor is campaigning to get things done.
24th Mar 2021, 4:41pm
Coun Stephen Bunney in Church Street EMN-210321-162713001
In an open letter to the county's highways department and the Highways and Transport, Portfolio Holder Coun Richard Davies, Coun Stephen Bunney has highlighted the dangerous state of the roads and patchy repairs.
Coun Bunney said: "As a District and Town Councillor, I receive more complaints about the state of our roads than all the other topics combined.
"The main concern - POTHOLES! and the universal generally poor state of the road and pavements – making them a high risk as they frequently cause damage to motor vehicles, bicycles, mobility scooters and pushchairs.
"In many places it is not just one pothole but a whole series running for great lengths of highway.
"The state of repairs is also mentioned in that many of the potholes have been repaired only to reappear at the next cold spell and/or occasion of heavy precipitation and high surface runoff.
"The view is that the patch is applied to fill the hole, but the underlying cause is not being tackled.
"Clearly, this means that the money spent on repairs is not being used to maximum benefit and therefore is a wasteful use of limited Council resources.
"We are advised to report these substandard road conditions on-line using the Fix My Street App or LCC's Web Site.
"Frequently it is reported that the requested repairs have been carried out, but rarely to the complainer's complete satisfaction, as only the pothole reported is repaired and the others in the area left untouched.
"This frequently means a revisit for the maintenance team, or the expansion of the unrepaired pothole rendering the initial repair pointless. Another poor use of money and similarly a wasteful use of resources.
"To help resolve this issue, it has been suggested each pothole in an area should be reported on Fix My Street – though the scale of the problem makes this time consuming and so off putting.
"For instance, on March 20, I spent more than 35 minutes reporting the 40 plus potholes on Church Street, Market Rasen and even then, I combined them into nine separate batches.
"Surely, a more effective process would be for a local inspector/works planner or the maintenance team to review the general state of the road before work commences meaning that all the pot holes are repaired, especially if the state of the road has been commented on.
"Another frustration is the number of times a road is dug up in a relatively short period.
"Residents and Road users wonder why this work is not co-ordinated. The resultant surface after all the works are completed would be one hard wearing and sustainable continuous layer without the weaknesses of patches.
"I appreciate that pot holes are a gigantic problem and is regularly at the forefront of Highways, LCC and even Government thinking. There are some maintenance wins, but they are frequently short lived.
"To many residents, and myself, there is a need for a rethink to what can be done to both resolve, and finance, the problem."
Coun Bunney added: "I would welcome a public meeting (virtual if needed) with local councils and residents to let them air their concerns, digest the official response and make suggestions."
Stephen BunneyPotholesRichard Davies


text:
Q: Notepad++ find feature searches up the document or down the document. How to search all over If I search for a word using FIND in WordPad, it automatically searches down the document, when it reaches the bottom of the document it automatically jumps to the top and continues the search.
In Notepad++ this does not appear to be default behaviour.
In Notepad++ I am presented with a choice of searching, under the pane called direction - either up the document, or down the document. This is a pain, if I knew where the word I wanted to find was, I would not use the functionality.

Is there a way to mimic similar behavior of WordPad's find in Notepad++ (where I iterate through each matching string one at a time) and not have to manually change the direction to search the entire document?

A: The function you want can be made available by checking the "Wrap around" checkbox.

redpajama_set_name: RedPajamaStackExchange


Last week, when I was testing out ways to introduce the ideas to someone via Skype, I used a friend who knows nothing of personality typing and nothing remotely like Socionics.
She took the item from my hand and started turning it around, pressing on it, and started describing attributes about it. 'It's black, rectangular, light, thin, this side is heavier, there's an indented line running along the edge of it, if I didn't worry about breaking it, I'd try to pop it open there.' She started pressing buttons, nothing was happening, until she pressed one button, the Tv turned on. She pressed that button again, nothing happened. So she pressed a few different buttons, various things happened, and finally after a different button, the tv turned off.
I said, 'Ok, now, instead of this item, what if it was a person. How would you find out information about it? about me?' She said she would ask me questions. I said no, that's like reading the manual. How would you find out about me, by direct experience? She said she'd touch me. I said go on. So she started touching, pinching, pushing, pulling, turning me, etc etc, in similar fashion as she had done with the tv remote. Via this method, she learned how much stability and balance I have, how much pressure was required from her to push me back, that I made giggling and ouch sounds, etc.
I asked her, you found by pushing the buttons that the remote did certain actions, as part of being what it is. How would you find out what actions I do or would do, as part of being who I am? She said that if I was a puppet, she could pull my strings. But since I'm not, then she could try telling me what to do, and watch to see if I did it.
I tend to view Se as the information about the qualities of concrete objects (objects that we can pick up or manipulate in other ways).
How do we find out information about the concrete objects that are in our world? By doing things to them. We get into a car with gadgets we've never seen before, and we start flipping switches and pushing/pulling knobs and buttons. The action that happens after that lets us know some of the qualities of that car. We'll experiment with how fast the car goes when we press the gas pedal, or how the car handles when we have to suddenly apply the brakes.
I think Se gets its 'force' definition because to get the information about the object, you are having to manipulate it, which is generally done manually or mechanically. Part of the qualities of an object is what it does, so you have to get it to DO whatever it DOES.
Add in that a person can be treated as an object as well. So you want to find out the concrete qualities of a person? Get the person to DO something. One way is by a variety of 'rough housing'...here we get friendly (or not so friendly) pushing around, friendly (or not so friendly) punches, etc. The recipient of such behaviors may think the Se info processing is bullying, while the Se person may be thinking "hey, this guy's a good guy, a friend".
I think that this is also how Se gets its 'power' definition. Power is used as an example of an object's quality. But how do you determine something's power? By getting it to DO things.
Now, lest people confuse 'getting an object to DO something' as being 'dynamic', please remember that the qualities being looked for are qualities that are relatively consistent for that object.
The TPE are Readily Observable via Direct Experience. If I needed to communicate information about the TPE to you, I could just show you the TPE, and you would be able to extract the information yourself, using your own senses.
Some of the attributes you might get are visual (appearance, shape, form), auditory, kinesthetic (texture, pressure, resistance), smell, taste, and location in space. If you manipulate it enough, you may even get a sense of what it does, or can do.
You would obtain this information by coming into direct contact with the TPE. And if you've rich information of this type, you might use metaphors based on physical contact.
If the TPE is a person, some of the attributes might include their possession of other TPE... This gets into discussions of territory, who has what, who doesn't have it, and who wants it (desires it). Obtaining new TPE may be on your agenda, and may act as a motivating force for work. "He who dies with the most toys wins." And TPE usually cost money.
Being familiar with dealing with TPE identity, your language would distinguish this TPE, not that TPE, by pronouns such as this, that, him, her, I, you, we, us, them, they, and even actual names of the TPE.
Being aware of what TPE do, or can do, or how it can be used, your language might also use Actor Verb Object structure, such as "I beat you" as opposed to "I won".
Having full, rich sensory data at your 'mindtips', you might slip into describing a familiar TPE in the present tense, rather than past. Also, you already have the data from past TPE. You cannot experience future TPEs until the future, so you may also have a life philosophy of 'The past TPE are past, the future TPE have yet to come, far better to enjoy the TPEs now, while you can'.
ok, the above is written a bit silly, it was the only way I could get through the guidelines on this one.
One more story, regarding Se as 'Will".
My NiFe brother and I have typed our older brother as SeTi. The SeTi brother is constantly pushing people's buttons. Mine used to be a favorite of his to play with. How far could he push me before I'd push back, and which buttons did the trick. We couldn't be in the same room together for more than 5 minutes before we'd wind up in an all out yelling and potentially physically fighting match.
Yet, believe it or not, he and I were a lot alike, and used to have some decent conversations when we got along.
I half-joked to one of his grown-up kids, a passing reference of how often my SeTi brother and I fought. The joke took him aback. He asked me questions about those times, and was surprised that I truly had taken all that so personally and was hurt by those times. To him, I had freewill, to choose or not choose to engage him in those 'play-battles'. I had engaged in them, so he assumed I'd done so by choice, not because I felt pressured to defend myself.
It's like, with an object, like a remote or car, you press a button, it has to do what it's programmed to do. But with a person, they have freewill. They don't have to do what you tell them to do, they choose to do what you tell them to do.
Another example, one my NiFe brother used to tell me. Our SeTi brother used to try to get the NiFe brother to do stuff. He'd try to manipulate him and even tried to blackmail him. But it backfired. When blackmailed, my NiFe brother would just go and tell whoever it was the secret, and take the consequences that way. They'd both get into trouble. This would irk my SeTi brother "why'd you do that?" NiFe: because you tried to make me do something I didn't want to do.
Take a chance, experience a glimpse of what's it like to find out about a TPE by using your senses only. And then remind yourself that an Se ego type probably gets far more info from that TPE than you did, and his mind is filled with that kind of info at hand.
If you did the experiment, you may have noticed a change in how your eyes and mind reacted. Your eyes would have been more narrowed, focused on the TPE itself. Initially your mind may have wandered away from the topic at hand, maybe even saying to yourself that this is pointless. Guess what, if your mind wandered, you weren't doing the experiment. Your mind would have been just as focused as your eyes were.
Ok, so you've worked at it and were successful with the one TPE. Now look around your environment, at all the TPE that are around you. How much about them do you actually know? And imagine if you were to scan your environment with the same TPE visual and mental focus as you had looking at the one TPE. You might feel a bit like a predator, looking for it's next 'meal'. And now, imagine you're a person on the receiving end of such a TPE focused look. Feeling like running yet?


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text:
Q: How do you pass bearer token without using page url in ASP.NET? We have an ASP.NET MVC application based on the default Visual Studio SPA template. After a user successfully logs in, javascript reloads the page to call the OAuth authorize endpoint using this url
window.location = "/Account/Authorize?client_id=web&response_type=token&state=" + encodeURIComponent(window.location.hash);

Here is the server side code that handles bearer tokens
        PublicClientId = "web";

        OAuthOptions = new OAuthAuthorizationServerOptions
        {
            TokenEndpointPath = new PathString("/Token"),
            AuthorizeEndpointPath = new PathString("/Account/Authorize"),
            Provider = new ApplicationOAuthProvider(PublicClientId),
            AccessTokenExpireTimeSpan = TimeSpan.FromDays(14),
            AllowInsecureHttp = true
        };

The OAuth authorize endpoint responds with a 302 redirect with the access token in the url such as
https://example.com/#access_token=wKB_9sVptsGr...
Javascript extracts the token from the redirect url and uses that to authenticate with WebApi. This works beautifully as it allows us to be authenticated on both MVC side and WebApi side. However, this method of returning bearer tokens was identified as an issue during a recent cyber-security audit since the token is stored in the browser history exposing the access_token to other users.
Is there a better way to return a bearer token? We need both the MVC and the WebApi parts to be authenticated.
EDIT
Just to clear things up, this question is about the first time the server passes the access token to the browser. Not the browser passing the token back to the server.


New Zealand English Dictionary 1.0.1 for Firefox.
New Zealand English Dictionary 1.0.1 for Firefox. Includes New Zealand places, including major cities and towns, and major suburbs. It also contains NZ words, organisations and expressions.
Packaged up from OpenOffice's English (New Zealand) dictionary by Tristan Burtenshaw.
Copy the text, "Kia ora bro. Just paddling my waka down the Waikato river to meet the whanau at the marae. Need some bickies for smoko." into the search for add-ons text box above.
Right click the text box and select Check Spelling to turn on the spell checking.
Notice that the Kiwi words are underlined to indicate that they are misspelt.
Click on the Add to Firefox button above.
Click on the Install button on the Software Installation dialog window.
Right click the search for add-ons text box above and select Check Spelling to turn on the spell checking again.
Right click the text box again and select Languages -> English / New Zealand.
If the text above is missing from the text box, copy it again.
All the Kiwi words should now be marked as spelt correctly and not underlined.
Kako vam ugaja New Zealand English Dictionary?


How to learn latest swimming techniques?
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What would YOU like to see on the Coaches site?
Do You Coach Indoors? Take a look at this article.
On-Deck Coaches needed for Gresham!
Practice ideas for swimmer birthdays?
Question for a USA Swimming certified coach?
Who is going to the ASCA World Clinic?
Call for On-Deck Coaching in Atlanta!
Online Coaches Wanted for 2009!
Suggestions for those interested in coaching?
On-Deck Coaches Needed in Clovis!
COACHES Clinics - Your own local "SwimFest09!"
BUILDING my team's 18-29 Age-Group!
I have a note from Swimfest that says Armpit!
Who is headed to the ASCA World Clinic in FTL this Fall?
On-Deck Coaches Needed in Indy!
Any Coaches from SF Teams?
Excellent Resource - Swimming Anatomy!
Online Coaches Wanted for 2010!
FREE Club Banner from USMS!
how do I start a masters group?
Do I know a USMS coach located in any of these LMSCs?
What are the points for??
Our NEW Coach of the Year!
On-Deck Coaches Needed in Atlanta!
New coach here! Challenges and advice for the newbie??
Head Coach Wanted - Leading Tri Team in U.S.
Need a free online coach?
Countries you can make a living out of coaching Masters in?
2014 FINA World Masters Championship - Coaches Wanted!
No coaching clinic in the National Capital area this year?
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Thoughts on how to get swimmers to use equipment?
How to teach front-flip to children aged 8 and below??
How to swim? I have no experience with swimming .
Great Coaching Opportunity Mount Pleasant, S.C.


text:
The Missing Link? U.S. Policy and the International Dimensions of Authoritarian Resilience in the Arab World
Berger, LG (2011) The Missing Link? U.S. Policy and the International Dimensions of Authoritarian Resilience in the Arab World. Political Studies, 59 (1). 38 - 55. ISSN 0032-3217
In contrast to the hopes of some US observers, the so-called 'Baghdad Spring' of early 2005 did not mark the beginning of an era of sustained political reform in the Middle East. In an attempt to explain the resilience of authoritarian governance in the region, this article aims to demonstrate the insufficiencies of external democratisation efforts that rely on a crude reading of the 'modernisation' school of thinking and ignore the insights of the 'transition' school with regard to the international dimensions of democratisation. Case studies of Egypt and Saudi Arabia, two countries sharing close strategic relationships with the United States yet differing in the socio-economic foundations of authoritarianism and experiences with managing external and domestic calls for political reform, demonstrate that the unwillingness of the United States to condition its support for regional partners on human rights concerns constitutes one of the main reasons for the Arab world's 'democratic exception'.
Berger, LG
(c) 2011, Wiley-Blackwell. This is an author produced version of a paper published in Political Studies. Uploaded with permission from the publisher. The definitive version is available at www.wileyonlinelibrary.com.
United States of America; Political Change; Arab Countries; Authoritarianism (Political Ideology); Governance; Saudi Arabia; Egypt; Baghdad; Iraq; Human Rights
The University of Leeds
The University of Leeds > Faculty of Education, Social Sciences and Law (Leeds) > School of Politics & International Studies (POLIS) (Leeds)
Symplectic Publications
http://dx.doi.org/10.1111/j.1467-9248.2010.00853.x
Filename: Missing_Link_pre_copy_editing_version_2009_with_coversheet.pdf


The stylish supporters helped to raise over one million dollars for a project in Watts, California.
It wasn't all about the Super Bowl this weekend—in Los Angeles Saturday night, the chic set gathered for an important cause—the first annual PSLA Gala. The organization, founded by Rochelle Gores Fredston, found stylish supporters in Angela Lindvall, Holland Roden, Julia Sorkin, Sally Perrin and more, who helped to raise over one million dollars for the new Franky Gehry campus in Watts, California. The campus which is being designed pro-bono will be a center for healing and transformative change for thousands of children and families upon completion. Sutton and Christian Stracke were honored for their philanthropic and artistic contributions, while singer Tyrese Gibson shared an impromptu story about raised in the historic community in South Los Angeles. See the best looks from the night.


ahem!! We the peace loving Leaders (and budding astronauts) hereby declare that we will not de-nuclearize until the Warmongering running dogs Western Uber Imperialists Scum Bags and IAF Lackeys stop threatening our Happy Contented Well Fed and Free slaves people with a Preemptive Andrea Strike. so there .


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The Blog of EY in Switzerland.
On 10 February 2019, the popular vote in the canton of Basel-City has resulted in an important success for the Basel-City political parties, the Basel-City administration and the economic region. The "compromise for the implementation of Tax Proposal 17", has been accepted by a large majority. Authors: Andrea Bätscher and Dominik Bürgy.


This study investigated the causes of poor performance in mathematics among public senior secondary schools students in Azare metropolis of Bauchi state, Nigeria. The study sample was 361 in which 300 were students and 61 teachers which were selected from the population of 5,545. The descriptive survey design was used and questionnaire was used in the collection of data. Frequency and simple percentage were used in the analysis of the data. The findings of the study led to the conclusion that students' negative attitude toward mathematics, anxiety and fear of mathematics, inadequate qualified teachers, poor teaching methods, inadequate teaching materials, overcrowded classes were some of the causes of poor performance in mathematics in the study area. The study also found out that developing positive attitude, motivation and proper guidance toward mathematics, using proper methods of teaching the subject, provision of relevant teaching materials, additional classrooms and furniture, provision of libraries and mathematical laboratories were some of the ways of improving performance in mathematics in the study area. Finally, the study recommended that frequent inter-school competition in mathematics, frequent supervision and inspection by proper authorities as well as enlightenment of parents on importance of children's education should be adopted. Key words: Poor Performance, Mathematics, Public Senior Secondary Schools, Students.


The technology is a chemical method for preparing ultrathin oxide films on silicon with low leakage currents and high capacitance, optimizing the electrical properties of the dielectric barrier.
An alternative gate dielectric material will be required for scaling of microelectronic devices to continue at its present rate. The decreasing dimensions of the transistor have required thinner and thinner gate oxide films to maintain capacitance. Unfortunately, leakage currents through silicon dioxide film become too high when using films thinner than 2 nm. Alternative gate oxide materials with a higher dielectric constant have been sought, but the problem has been finding a material which will not form an interfacial layer of silicon dioxide between the high-k dielectric and silicon substrate, and can be deposited using an economically viable process. Continuous dielectric films for silicon based electronics of thicknesses far less than is possible with SiO2have been demonstrated, with high chemical purity and exceedingly low leakage current. This is accomplished through repeated condensation-hydrolysis reactions using n-propyl orthozirconate. The resulting materials will permit the best FET gate material, and when combined with other innovations, the lowest power, highest speed transistors possible.
The primary application for this technology is for integrated circuits; processors and memory applications are the main applications for IC (integrated circuit) technology.
Other applications would include sealing or passivation of silicon surfaces in electronics and capacitors on chips.
This technology is a method for making modifications to semiconductor wafers on an atomic scale, creating "nanowires" or "nanoclusters" on a commercially viable scale. These types of modifications will become more important as the line-widths of processors decrease beyond the physical limits of current production techniques. In this case, transistors and other components will have to be made at the atomic level to improve performance and speed. Estimates based on Moore's Law suggest that production techniques using atomic-level techniques will be required at line-widths of less than .05 m (currently .13 m for Pentium 4 processors), which will be required in about 10-12 years.
The invention relates to a method for forming atomic-scale structures on a surface of a substrate on a large-scale. The method includes creating a predetermined amount of surface vacancies on the surface of the substrate by removing an amount of atoms on the surface of the material corresponding to the predetermined amount of surface vacancies. Once the surface vacancies have been created, atoms of a desired structure material are deposited on the surface of the substrate to enable the surface vacancies and the atoms of the structure material to interact. This interaction causes the atoms of the structure material to form the atomic-scale structures. The method overcomes the slow production levels and narrow modification area of current techniques, which require scanning tunneling microscopes (STM) and can take months to produce a single modified 8 inch wafer. It allows parallel fabrication of the atomic level structures, which allows more rapid, large-area simultaneous production, and therefore makes production of these structures commercially viable. The structures that could be fabricated using this technology include quantum-dot devices, nano-scale interconnects, ultra-high density information devices, and nanowires.


Our Simple Web Publishing system is a great way to get a bespoke website designed for you, that leaves you in control of the content. It pairs our great Web Design with a systems to allow you to easily manage your website's content.
For a quick run down of why this is a great solution for you, check out the Features and Benefits of Simple Web Publishing.
A lot of companies will try to sell you website design, they will design you a website, and put the content that you give them on it. You pay your money, and you get a website. Sounds easy, but a good website, that is useful for it's owners and users, has to be kept up-to-date and fresh, otherwise people just don't come back. This is a bit of a problem if the firm who designed your website charges £200 every time you want to change anything.
At Software Systems OFB we'll design a attractive and easy to use website to meet your needs and convey the messages you want, fill it with your content, then it's over to you. All our designs are created as one-offs, so your website will be unique, not a the generic off-the-shelf template that some others will try to sell you. As our websites are created using a wiki-based system, you can easily change the content as much as you like, add, remove and edit pages, all password protected of course. We'll get you started, show you how it all works, then it's all yours, no support or maintenance fees, no lock-in and no nonsense. Of course, we're always there if you need support, a new feature or just a bit of advice.
This is probably what the industry would call CMS Lite, if you need something a little more sophisticated, we can do that too.


Home Page >> News Articles >> Johnson & Johnson Charite Spinal Disc Un..
Chicago, IllinoisThe Pulaski and Middleman law firm in Houston, Texas heads a group of law firms that represent over 350 injured Charite spinal disc recipients. The patients allege that the disc is defective, that the device was improperly marketed and that the company did not adequately warn of the disc's dangers.
The Charite artificial disc was first approved for use in the US in October 2004, although it had been used in the European market since 1987. The device was approved to relieve pain by replacing the damaged disc with the Chirate disc, as an alternative to the surgical procedure known as lumbar spinal fusion surgery.
The disc was developed with the premise that segmental mobility will improve outcomes, as has been the case for artificial hip and knee replacements. The current Charite disc is the third modification of a device first developed in 1982 by Buttener-Janz and Schellnack at the Charite Clinic in the former East Germany.
DePuy Spine, a division of Johnson & Johnson, acquired the Link Spine Group in 2003, and gained exclusive worldwide rights to the Charite disc. Since the disc was approved, more than 5,000 people have received the implant in the US, according to DePuy Spine's Bill Christianson, vice president of regulatory affairs, in USA Today on July 25, 2006.
At present, experts claim, the best candidates for disc replacement are adults who have disc degeneration in only one disc in the lumbar spine, either the disc between the fourth and fifth lumbar vertebrae or the disc between the fifth lumbar vertebra and the sacrum.
Under FDA guidelines, before disc surgery, individuals must have undergone at least 6 months of treatment, such as physical therapy, pain medication, or wearing a back brace, without showing improvement, and must be in overall good health with no signs of infection, osteoporosis or arthritis.
"If a patient receives an artificial disc, but the disc that was replaced was not actually the cause of the patient's pain, then the patient will have undergone an extensive, invasive and costly procedure but still have the same level of pain. This may seem like an incredibly obvious point, but with back pain it is often difficult to pinpoint the precise cause of a patient's pain. Accurate and careful diagnosis of the patient's pain generator is crucial and cannot be overemphasized.
"If the patient does have a painful disc, but other factors (such as significant degenerative changes in the facet joint) are present, then the patient may have to undergo a revision surgery after the initial surgery to either correct the placement of the disc or fuse the spine—a situation that is definitely best avoided by correctly assessing all the risk factors prior to the first surgery."
Many critics contend that the Chirate disc is just as big a threat to patients as the problems it is supposed to cure. The disc has been promoted as an alternative to fusion; yet, even in the short term studies, spontaneous and surgical fusion occurred.
The disc is required to function for many years, but information about long term benefits and risks, such as satisfaction, adjacent segment problems, and rate of re-operations, is not available because only one short term study, with a 24 month follow-up, was presented to the FDA when the disc was approved.
And even that study has come under attack because the benefits of the Charite in the context of a noninferiority trial, were shown to be noninferior to Bagby and Kuslich cages (BAK), used in spinal fusion, a failed procedure critics say that has not been performed in years.
The 2- year trial showed only that the disc was no worse than this specific type of spinal fusion surgery, according to a May 2005 FDA report.
Overall, the study found that 57% of Charite patients achieved "overall clinical success," compared with 47% of the spinal fusion patients. However, more than 3 out of 5 Charite patients, deemed successes, were still taking narcotic painkillers 24 months after surgery.
In addition, a higher number of Charite patients suffered severe or life-threatening events than spinal fusion patients, 15% compared to 9%, according to the FDA review.
Clinical success in the trial was defined by four criteria: (1) more than 25% improvement at 24 months after surgery, (2) no device failure, (3) no major complication, and (4) and no neurologic deterioration.
"1) only 57% of disc replacement patients and 46% of BAK fusion patients met these four limited criteria; 2) in patients who were considered a clinical success at 24 months, 64% of the Charite group and 80.4% of the control were using narcotics; 3) at 24 months the change in VAS and ODI did not differ statistically from control; 4) the SF-36 PCS and MCS composite scores did not differ statistically from control; 5) no difference in operative time or blood loss between the two groups."
"Revision surgery for a failed disc arthroplasty is life threatening. Dealing with the scarring around the great vessels is the main challenge. Indeed, the location of vital vascular structures may make it altogether impossible to perform such anterior abdominal exposures."
Other postoperative difficulties such as infection, persistent pain, instability, and osteolysis can also occur (Santos, Polly et al. 2004).
In recent years, the cost benefit of surgery for degenerative disc disease has come under scrutiny. The 2005 Cochrane review of surgery for degenerative lumbar spondylosis states, "There is no good evidence on cost-effectiveness" (Gibson, Wassell 2005).
Concern over the cost benefit has been expressed specifically for the artificial disc. Within 5 years of its release, the CMS noted, it was predicted that spinal arthroplasty (lumbar and cervical) could reach an annual cost of $2.18 billion in the US, with the suggestion by Singh that this estimate is conservative (Singh, Vaccaro et al. 2004).
Santos stated, "...long-term clinical outcome using validated instruments are necessary to justify the added cost of these procedures."
Dr Sohail Mirza, a medical professor at the University of Washington, criticized Charite's marketing slogan of "natural motion is back." It "implies that the artificial disc creates a normal spine; it does not," he stated last year in the journal Spine.
"Contrary to optimistic marketing, the data," he wrote, "argue for caution by patients and surgeons. Hope for a cure of back pain and a marketing bonanza must be held in check."
As of July 2006, more than 130 serious adverse events have been reported to the FDA associated with the Chirate disc.
In 2005, the FDA performed an analysis of adverse events reported in the Manufacturer and User Facility Device Experience Database (MAUDE), at the request of CMS. The analysis includes Medical Device Reports (MDRs) that were entered into the database between August 11, 2003 (first report received) and November 16, 2005.
A total of 101 MDRs were analyzed for 96 patients, with 1 MDR for the Prodisc device in addition to the Charite devices.
The most frequently reported event was device migration out of the implanted location, with 54 of 96 patients (56%) experiencing this effect. Seventy-six patients (79%) had a second surgery to remove all or part of the implant, to correct problems with the device, or to correct problems produced during the surgery. Fifty of the 76 (66%) patients had second surgery due to device migration.
The most common second surgery was to remove all or part of the disc followed by spinal fusion of the implanted motion segment. Twelve patients had 2 prostheses placed despite the device labeling for only one device implantation. Most adverse events that required second surgery occurred in the first 2 months after implantation. Two deaths were reported which were both attributed to pulmonary emboli.
Dr Charles Rosen, associate clinical professor of spine surgery at the University of California, Irvine, told the LA Times on August 5, 2006, that he has seen 10 patients since late last year, complaining of worsening pain after receiving the Charite disc and that some patients suffered fracturing and an abnormal pulling apart of the joints of the spine.
He says the Chirate is unsafe and should never have been approved because a 2-year study is too short for a disc that will remain in the spine for many years with implant patients averaging 40-years old.
"There is no solid evidence that this will last for more than five or 10 years and they will not need to have another operation," Dr Rosen said.
According to Times, Dr Allyson Fried-Cain, 52, a former foot-and-ankle surgeon, has sued the device maker, saying she suffered such an increase in pain after a Charite disc implantation that she lost her practice and had to sell her home in Marina del Rey, California.
Dr Fried-Cain, a former marathon runner whose back injury resulted from a car accident, told the Times, "I couldn't do surgery anymore. I couldn't bend over,"
"This implant has destroyed my life," she said.
According to the Times, spinal surgery is becoming a very lucrative business, "with at least $3.2 billion spent last year in the U.S. on spinal fusion."
In August 2006, the FDA approved the ProDisc-L, made by Swiss medical device maker Synthes Inc, which is expected to compete against the Charite.
In its approval letter to Synthes, the FDA said patients receiving the disc should have tried at least 6 months of "conservative" treatment with other therapies such as exercise and medication.
As a condition of approval, Synthes agreed to continue studying the disc for long term safety and effectiveness in a study involving at least 286 patients. The company is also required to conduct a yearly analysis of major adverse events and report the number of devices sold and implanted each year.
The booming spine surgery industry suffered a serious financial set-back earlier this year, when the Medicare program stopped paying for the Charite disc in patients over 60, noting that the surgery costs between $30,000 and $50,000, and has not sufficiently been tested for long term affects. The CMS stated "that the evidence is not adequate to conclude that the Charite lumbar artificial disc is reasonable and necessary."
"Therefore," the CMS memo concluded, "we propose to issue a national noncoverage determination."
If you or a loved one has experienced adverse affects from a Charite spinal disc implant , please send your [Charite Spinal Disc] complaint to a lawyer for a free case evaluation.
Hello,my sister has had one of these stupid Charite disc's put in Qld Australia in 2004.She has had never ending problems after having put in.Please let me know what or who the hell to contact about this here/there.She has been told by doctors (not the one that placed the disc as he will not contact her back)that she is a walking time bomb and is in extreme pain and not wanting to move for fear of what may happen.Now living in Adelaide south Australia to be with us (family) for help with daily life..It is incredibly frustrating to watch her suffer due to poor products that would seem not studied or tested properly.The company needs to be accountable.Her name is Janette Cain...please, please help anyway you can!


"He was trying to not put his body weight on the quarterback and that happened", Dolphins coach Adam Gase bluntly said Monday of Hayes' injury, via the Orlando Sentinel's Omar Kelly. Miami Dolphins defensive end William Hayes will miss the rest of the season with a torn ACL he sustained while attempting to avoid landing on Oakland Raiders quarterback Derek Carr and earning a penalty. To say the least, the 33-year-old now faces an uncertain future. Your foot plants awkwardly into the ground for a half-second, and boom. "He's one of our leaders and best run defender", Gase said. "It's going to be a tough one for us to swallow". "Long as the QB is safe", 49ers cornerback Richard Sherman tweeted in response to the news about Hayes. Gase did not elaborate on whether he thought the new rule caused Hayes's injury. "I'm just telling you what he did".
Matthews had been sanctioned for what appeared to be a textbook tackle on Minnesota Vikings quarterback Kirk Cousins on September 16.
According to the new National Football League rule change, aa defender laying their body weight on a quarterback after a tackle or sack equals a a 15-yard roughing the passer penalty.
Matthews criticised the decision following the Packers' 31-17 loss. I understand the spirit of the rule, I said that weeks prior.


I've gone very summery with this outfit, as it's only when the sun is shining that I'm decked out in such light colours. This outfit was put together while I was on my trip through the south of France, specifically on a particularly nice day when I ended up on the beach for a while. This skirt is very light and comfortable - although not ideal in the wind, trust me! - and I think the stripes give it a slightly nautical vibe, which was appropriate for being by the sea. Normally I wouldn't wear jewellery to the beach, but as I wasn't in a bikini or about to go swimming, I thought I'd add some small pieces. The shoes were chosen for practicality's sake, as I've been doing a lot of walking whilst on my travels, but they go well with the skater-style of the skirt.


This content is courtesy of Churchill Downs Communications.
LOUISVILLE, Ky. (Friday, May 5, 2017) – China Horse Club and Clearsky Farms'Abel Tasman rallied from far back and then held off a late bid from Daddys Lil Darlingby 1 ¼ lengths to win the 143rd running of the $1,000,000 Longines Kentucky Oaks (Grade I) for 3-year-old fillies before a crowd of 105,100 on a cold and rainy Friday afternoon at Churchill Downs.
Trained by Bob Baffert and ridden by Mike Smith, Abel Tasman covered the 1 1/8 miles on a sloppy track in 1:51.62.
It was the third victory in the Oaks for Baffert, who previously won withSilverbulletdayin 1999 and Plum Pretty in 2011. For Smith, it was second victory in the Oaks to go with Princess of Sylmar in 2013.
Favored Paradise Woods and Miss Sky Warrior blazed through fast early fractions of :22.79 and :46.24 with Abel Tasman racing at the rear of the field. The two leaders continued their duel into the far turn with Paradise Woods the first one to crack but by then the rest of the field was closing in.
Smith had Abel Tasman in the clear outside of horses and swept to the lead at the eighth pole and had more than enough to hold off Daddys Lil Darling.
The victory was worth $564,200 and increased Abel Tasman's earnings to $912,060 with a record of 7-4-2-0. It was her second Grade I victory to go with a triumph in the Starlet last December at Los Alamitos.
Abel Tasman is a Kentucky-bred daughter of Quality Road out of the Deputy Minister mare Vargas Girl.
Abel Tasman returned $20.40, $9.20 and $6.40. Daddys Lil Darling, ridden by Julien Leparoux, returned $11 and $6.60 with Lockdown, who finished another length back, returning $18.40 to show under Jose Ortiz.
It was another half-length back to Vexatious, who was followed in order bySalty,Sailor's Valentine, Tequilita, Miss Sky Warrior, Ever So Clever, Mopotism, Paradise Woods, Jordan's Henny, Wicked Lick and Farrell.


London has lost 35 per cent of its grassroots music venues since 2007 according to a report. The number of spaces programming new artists has dropped from 136 to just 88. The London's Grassroots Music Venues Rescue Plan, produced by the Mayor's Music Venues Taskforce, suggests that whilst London's music industry is generating billions for the economy it's under threat at a grassroots level.
The Mayor of London Boris Johnson says: 'From the Rolling Stones to David Bowie, the Clash to Oasis and Ed Sheeran to Adele, grassroots music venues have played a key role in enabling some of the biggest names in music to develop as artists and to build audiences. They are the incubators for the stars that go on to pack stadiums in London and across the world. The Music Venues Taskforce report makes it clear that protecting live music venues is crucial to London's continued position as the music capital of the world.
The Rescue Plan identifies a range of factors for grassroots music venues closing and continuing to be under threat. This includes rising rents and licensing restrictions; noise complaints by resident and landlords selling venues to developers to turn into housing.
As final preparations for tonight's MOBO Awards ceremony are made, ITV London spoke to Ms Dynamite about the musical talent across London.
Jessie J has sold her London home and is leaving the UK because she is sick of speculation about her love life. The 26-year-old has bought a property in Hollywood where she says her talents as a singer are more appreciated.
"I've dedicated my life to singing and I want it to be taken seriously. Here it seems that all people want to know is what I've had for breakfast and who I'm sleeping with," she told the Mail on Sunday.
In 2011 the former coach on The Voice came out as bisexual and is often questioned about her sexuality.
"I'm the sort of person who will order ribs on a date, or the spaghetti bolognese and get it all down my front. And I'm too full-on as a date, too intense. It's like, if I'm going to be someone's girlfriend I have to be a really good girlfriend, which can be a bit much for some people. Maybe I should relax more," she said.
The Libertines featuring front-man Pete Doherty are to reform to headline London's Hyde Park festival this summer.
The band mates last reunited in 2010 where they performed at Reading/Leeds Festival after splitting in 2004 so co-frontmen Doherty and Carl Barat could pursue their own careers.
The reunion will not come as a complete surprise to fans of the band as Doherty hinted a show was on the cards in a recent interview, and the band's Facebook page featured an image of Hyde Park.
The Libertines, will play at Barclaycard Presents British Summer Time in Hyde Park on July 5, with the Pogues, Spiritualized and McBusted also set to perform at the festival.
Tickets go on sale on Friday May 2nd.
Cornershop, the band behind the 90's mega-hit 'Brimful of Asha', will open the 'world's smallest disco' in Stoke Newington, Hackney tomorrow to mark Record Store Day.
The group will be playing tunes and selling music in a bid for the world record.
They hope that the small venue inside a record shop on Albion Road will be officially recognised as having a capacity of just 14.


It is understood the Egyptian Olympic Committee chose a vendor for its athletes� training and village wear who supplied counterfeit clothing bearing the Nike brand.
@MohSeif yes it is .The bags for example have big nike logo in the front and the zippers are addidas :) a lot of funny stuff too.
"Nike�s authorised distributor in Egypt has sent two official communications to the EOC on this issue and no response has been received.
Hmmm, with increased security at the 2012 Olympics this incident definitely needs to be looked into thoroughly.


text:
Die Kanzleischrift  () ist eine der fünf Hauptkategorien der chinesischen Kalligrafie.

Die chinesische Kanzleischrift wurde entwickelt, um mit einer schneller auszuführenden Schrift die Menge an offiziellen Dokumenten in den Kanzleien zu bewältigen. Der Legende zufolge soll ein Gefängniswärter aus der Qin-Dynastie namens Cheng Miao () die Kanzleischrift durch Abwandlung der Siegelschrift erfunden haben. Die Zeichen sind geradlinig strukturiert, eher breiter als hoch und weisen oft geschwungen auslaufende Einzelstriche auf. Diese Schrift war angenehmer zu schreiben als die Siegelschrift, und man sparte dadurch viel kostbare Zeit.

Wegen ihrer guten Lesbarkeit wird die Kanzleischrift in China bis heute zum Beispiel für Überschriften, auf Plakaten und in der Werbung eingesetzt.

Siehe auch: Orakelknochen

Weblinks

Chinesische Kalligrafie

redpajama_set_name: RedPajamaWikipedia


text:
HomeBasketball ZoneLakers Plans For Stanley Johnson, Revealed
The Los Angeles Lakers have a good player option for the spot they created through the three-team trade including Denzel Valentine. A talented player joined the team through a 10-day deal. The Lakers have to make plans for Stanley Johnson and his future with the team. He is a valuable player and can easily find his home in Los Angeles.
Stanley Johnson's Closeout Attacking >> pic.twitter.com/oYF6vOWv54
— Vinay Killawala (@vkillem) December 29, 2021
In his first game as a Laker, Johnson showed great performance. He had a really good outing with the Lakers and fans seem to have accepted him as a real member of the team. This will definitely play a big role in the decision Vogel and Rob Pelinka are about to make. Will the Lakers give Johnson another deal? A longer one?
Lakers to make plans on Stanley Johnson and his future
Vogel didn't reveal much about Johnson's future with the team. It all depends on the latest development of events.
Stanley Johnson is the type of player that will pay dividends for this team.
Not only does he bring size at the wing but he CARES. Energy and effort will always be infectious.
He's young and wants to prove he belongs in the NBA. That matters. #LakeShow pic.twitter.com/3tqOIlw3Bv
— Omar Siddiqi (@osid24) December 26, 2021
"I don't know what real detail I can go into on that," Vogel said. "Other than we still hope to have him back for some more games. All those answers will reveal themselves over the next few days…(Rob Pelinka) and (Kurt Rambis) are gonna make those decisions as they see fit, and that will all play out in the next few days."
Vogel says the Lakers "still hope to have (Stanley Johnson) back for a few more games".
LA can sign him now for the season, or wait until Jan. 5 and do another 10-day. The latter option would force him to miss the Kings game and make him available to be signed by another team. https://t.co/gDvdAnHBp0
— michael corvo (@michaelcorvoNBA) January 3, 2022
The head coach made similar comments a few days ago. It was too soon for the Lakers to make a decision on Johnson. Vogel admitted that Johnson "has done a great job" for the team, and he really praised his "toughness and hustle." Lakers coaches evaluated Johnson's performance through his deal.
The Lakers have regained control over the situation. They lost many games but many players have cleared COVID protocols and recovered from their injuries. Anthony Davis will return in the near future. Johnson could be a good fit for the current roster. He makes a good point for the team.
Pelinka took into consideration all the tradeable assets on the table. Some say he should get rid of some of the veterans and replace them with younger ones. Let's see what happens next.
Tags:Franchise, Lakers, Plan, Stanley Johnson
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