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News > Medscape Medical News > FDA Approvals
FDA OKs Nusinersen, First Drug for Spinal Muscular Atrophy
Megan Brooks
The US Food and Drug Administration (FDA) has approved nusinersen (Spinraza, Biogen and Ionis Pharmaceuticals), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease.
SMA, which affects around 1 in every 11,000 births, is a progressive motor neuron disorder causing muscle weakness and difficulties breathing and eating. There is wide variability in age of onset, symptoms, and rate of progression. Nusinersen is approved for use across the range of patients with SMA, the FDA said.
Nusinersen, which is administered via injection into cerebrospinal fluid, is an antisense oligonucleotide aimed at increasing concentrations of survival motor neuron (SMN) protein, which is underexpressed in SMA.
The efficacy of nusinersen was shown in a clinical trial in 121 patients with infantile-onset SMA who were diagnosed before 6 months of age and who were younger than 7 months at the time of their first dose. Patients were randomly allocated to receive an injection of nusinersen or a mock procedure without drug injection (control group).
An interim analysis performed at the request of the FDA showed that 40% of patients treated with nusinersen achieved improvement in motor milestones, as defined in the study, whereas none of the control patients did.
Additional open-label uncontrolled clinical studies were conducted in symptomatic patients who ranged in age from 30 days to 15 years at the time of the first dose, and in presymptomatic patients who ranged in age from 8 days to 42 days at the time of the first dose.
"These studies lacked control groups and therefore were more difficult to interpret than the controlled study, but the findings appeared generally supportive of the clinical efficacy demonstrated in the controlled clinical trial in infantile-onset patients," the FDA said in a news release.
"There has been a long-standing need for a treatment for [SMA], the most common genetic cause of death in infants, and a disease that can affect people at any stage of life," Billy Dunn, MD, director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research, said in the release.
"As shown by our suggestion to the sponsor to analyze the results of the study earlier than planned, the FDA is committed to assisting with the development and approval of safe and effective drugs for rare diseases and we worked hard to review this application quickly; we could not be more pleased to have the first approved treatment for this debilitating disease," Dr Dunn said.
"With the approval today of SPINRAZA, the future for those affected with SMA has changed. We are especially pleased that this sophisticated and rigorous clinical development plan has resulted in a broad label that may offer access to many patients," said Kenneth Hobby, president at Cure SMA, in a company news release. "This has been a story of all groups — families, researchers, companies and the FDA — working together as one community."
The most common adverse effects seen with nusinersen were upper respiratory infection, lower respiratory infection, and constipation. Warnings and precautions include low blood platelet count and renal toxicity. Neurotoxicity was observed in animal studies.
Nusinersen had fast-track designation and received priority review by the FDA. The drug also had orphan drug designation, which provides incentives to assist and encourage the development of drugs for rare diseases.
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Reuters Health Information ©
Cite this: FDA OKs Nusinersen, First Drug for Spinal Muscular Atrophy - Medscape - Dec 23, 2016.
Disclosure: Megan Brooks has disclosed no relevant financial relationships.
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Diseases & Conditions Focal Muscular Atrophies
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Diseases & Conditions Kugelberg Welander Spinal Muscular Atrophy
2010spinraza-nusinersen-1000135
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Focal Muscular Atrophies
Kugelberg Welander Spinal Muscular Atrophy
Physical Medicine and Rehabilitation for Limb-Girdle Muscular Dystrophy
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Phakomatoses (Neurocutaneous Syndromes): Multiple Systems Involved
EMA Seeks to Issue Guidance on Liver Damage From Novartis' Gene Therapy
Strong Link Between Muscle Strength, Mobility, and Brain Health
New Treatment Benefits Children With Spinal Muscular Atrophy
FDA Drowning in Orphan Drug Applications


Marcus Morris is the twin brother of Markieff Morris, although you could maybe put that the other way too, but either way Morris is a sold role player for the Boston Celtics right now. He was the 14th overall pick back in 2011, and played college ball at Kansas. Morris had a slow start to his career, basically it took getting out of Houston to start getting minutes and producing more offensively. He is a 36% three point shooter, and 42% from the field over his career. Morris has taken on more of a bench role, but could start for a handful of teams.


Lissa Thomson has been promoted to senior vice president, chief consultant for Lockton Benefits Group's Southern California operations.
In this newly created position, Thomson will serve a critical role in driving new business development and providing senior support to Lockton benefits consultants regionwide. She will collaborate with and serve as a resource to Lockton benefits consultants and accounting teams in analyzing benefits needs of clients and formulating creative strategies to evolve their programs, said Jim Czesak, chief operating officer of Lockton Benefits Group's Southern California operations, in a press release.
Thomson will also continue in her present position as member of Lockton's national Strategic Initiative Group.
According to the announcement, Thomson is a recognized benefits expert with more than 27 years serving in executive positions at some of the nation's top consulting brokerage firms. She is frequently invited to speak at industry conferences and events including San Diego Compensation and Benefits Association and regional Risk Insurance Management Society (RIMS) meetings, University Conference Services' National Health and Welfare Plan Management Conference, and the First Health National Conference.


Background: It has been reported that retinoids may lead to hormonal alterations. Aim: In this retrospective study, we aimed to study the effect of acitretin on pituitary hormones in psoriasis patients. Methods: Out of 50 patients intended to be studied, blood samples of 43 patients could be tested before and after 3 months of acitretin therapy (0.2 to 0.5 mg/kg/day). Results: Patients mean ± standard deviation ages and female/male ratio were 46 ± 17 years and 19/24, respectively. After treatment with acitretin, gammaglutamyltransferase, alkaline phosphatase, total cholesterol and triglyceride levels increased significantly (P < 0.05). After treatment, total protein, free thyroxine (T4) levels decreased significantly (P < 0.05). No significant differences were observed between before–after acitretin treatment regarding pituitary hormone levels in psoriasis patients (P > 0.05). Limitations: The retrospective nature of the study, inability to retest blood samples of 7 patients at 3 months post treatment, low dose and short duration of acitretin treatment were limitations of this study. Conclusion: This study showed that pituitary hormones were not affected except free T4 (thyroid hormone) by acitretin treatment. Further experimental and clinical studies are needed to clarify the effect of acitretin on pituitary hormones.


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Infiniti Pro Series: Pikes Peak 100
Topics: Pikes Peak 100
Aaron Fike
Ron Hemelgarn
Arie Luyendyk, Jr.
FOUNTAIN, COLORADO
MODERATOR: Arie, car gets stronger for you obviously as the race went along.
ARIE LUYENDYK, JR.: Right. We came to the track. We struggled with our setup. We thought it was motor-related. When we really looked at the data, it wasn't. The car was handling that bad. We were actually over two seconds slower than the quickest time yesterday in qualifying. We had a lot of work to do. We kind of gambled with the setup, and it actually turned out to be a really good car. When I was driving around the second lap, I could feel the car considerably better than it had ever felt this whole weekend. I was happy. The car handled great. It was great behind other cars, too. It was just a matter of time before I went to the front.
MODERATOR: Had there not been showers, obviously you could have improved your condition.
ARIE LUYENDYK, JR.: Yes, I think so. When Jeff's tires got warm, he was consistently two- to three-tenths slower than me. It was just when I got beside him once, I just didn't make it stick. So Jeff did a good job. We had a good race. I think I could have made it to the front. I was going quicker than the leader. It was just a matter of time before I made it there. Just ran out of time with the rain.
MODERATOR: Questions.
Q. This is your first time here at Pikes Peak. Talk about your impressions of the racetrack.
ARIE LUYENDYK, JR.: I think it's a great track, especially for a one-mile, just because I think there's so many passing opportunities because if your car is pushing, you have to enter the corner high. That allows a guy whose car is better to go low. It made a lot of good passes going into one on the inside and the outside. I think as far as a one-mile oval, I really like it, because there's so many places to pass, as opposed to Phoenix, which was a little bit more difficult for me.
MODERATOR: Jeff, obviously started on the pole. Had a great run yesterday in qualifications. Finishing second here today. 1999, 1998 Barber Dodge champion. Won the Infiniti Pro Series pole. I know we talked about it yesterday. It obviously was a situation where you did have an opportunity to test here a couple of weeks ago. It really didn't help you that much just simply because the weather was bad.
Q. You guys are going to Nazareth in August. Compare this track with the Nazareth track, four turns that are pretty well the same, whereas Nazareth you have as many as five turns.
ARIE LUYENDYK, JR.: We don't run Nazareth.
Q. You don't?
ARIE LUYENDYK, JR.: No. We're not going to Richmond either. We're going to St. Louis and Nashville.
Q. Gateway has two different types of turns. All four are the same here, right?
ARIE LUYENDYK, JR.: I think as far as the two tracks, St. Louis is a bit less of a momentum track. I think here you really have to keep the momentum up, especially with the horsepower our cars make. Here with the altitude, it kind of brings the engine power down. So it's a lot more momentum here. You'll see a guy run flat three laps in a row, and the third lap could be four-tenths quicker than the first lap he went flat. It's all momentum. St. Louis, last year we downshifted, most people did, for one of the corners, so it was less of a momentum thing.
Q. What was the difference of the setup in your car from qualifying to today? Obviously a vast difference in speed. Did you have a height adjustment?
ARIE LUYENDYK, JR.: Rake, springs (laughter). Basically everything was different. Steve Ericsson did a great job on doing that. So we went back -- we came here with a totally different setup, and that didn't work. We went back to our Phoenix setup. That didn't work. So then we kind of went totally off, either we're going to do good or less. Made some great changes and the car was perfect.
Q. How difficult is it when you come in here and you've got such a short period of time to get the car set up? You're not out there very long and you have to figure out a race and qualification setup?
ARIE LUYENDYK, JR.: You saw the guys who tested, Cory and Aaron and Jeff. They all really shined here because obviously they had experience on the track, where we came here with a setup that wasn't right, and we had to completely change it. We basically missed one session. It's pretty crucial to come off the trailer and be fast. I think the testing really played a big part here.
Q. How is this series compared to the Barber Dodge?
MODERATOR: Congratulations, Aaron. We know you like this track. It had to be pretty sweet for you to win here today.
AARON FIKE: Definitely. We talked about when we came out here and tested. This is probably one of my favorite tracks. I've always seemed to have really good luck. Ron Hemelgarn and Roger Johnson, the crew gave me a great car today. Everything stayed together. Obviously this gets the momentum going for Kansas and we can get a win there.
MODERATOR: Questions for Aaron Fike.
Q. Have you actually won a race here in midgets?
AARON FIKE: No. I think our best is a second so far. I think a third or fourth in the midgets. We've ran in the Top 5 I think the last three years we've been here. We just can't get over the real hump there.
Q. (Inaudible)?
AARON FIKE: Hopefully. It conflicts with Kansas. We're hoping to. It conflicts with Kansas on the practice day. I don't know if they're going to skip the practice day and run Pikes Peak. I would imagine that's what we're going to do.
Q. You pretty much had the field covered today. Did you make a lot of changes, many changes in the car from qualifying to the race? You seemed to have everybody pretty well gone?
AARON FIKE: Ever since we unloaded the car, we were pretty fast. My second gear seemed like it went all the way down the straightaway until I went into third and fourth gear. Those were really quick. I don't know, I was real worried about Jeff there when we got the yellow. I was being pretty conservative with the car throughout the whole race, had quite a bit left actually. You know, it was great for the team and great for me. Hopefully we get some momentum going for Kansas.
AARON FIKE: He had some smart-ass comment (laughter). I forget what he said. Something over the radio.
Q. How much did the test help? You had some pretty good time on the track.
AARON FIKE: Not really. If you remember, it was probably 30, 40 degrees. It was windy. It was pretty cold that day. We probably ran 40 laps. But, you know, we got the gears where we wanted to, what we thought we were going to run. It definitely helps to test anywhere, to get some laps, not only for me, but for the car and the crew.
Q. It snowed that day, too?
AARON FIKE: Yeah. It was like a blizzard out.
Q. This team has been fairly decent, fairly consistent. How much of an effort are you putting into this program to take the driver you have here and move him up into the IndyCar Series?
RON HEMELGARN: That's been the plan all along from when we first started to race last year. Running two years in the Pro Series and run him up into IndyCar. Obviously, many factors are involved in that. You have to have sponsorships. Working on that very hard. A couple years in this I think it's very, very important for any driver to move up. It gives you a lot of track time. Basically you have to get that horsepower behind you and then learn how to work in traffic and so on. Yeah, that's the goal. That's been the goal from day one. I think that's very achievable. To bring a guy out of USAC and bring him into this series I think would be fantastic.
Q. You said it was windy when you tested. It started gusting in turn four. Was that a concern?
AARON FIKE: Yeah. We started out the race a little bit tight. As the wind picked up coming off of four, pushed the front end down. Obviously, made the cars tighter. I'm sure everyone was having problems with the push, especially running in traffic. I wasn't the only one having problems passing people or getting by lap cars, I don't think anyways. It definitely made the cars tighter and tighter as the race went on.
Q. Anybody concerned the fact essentially there were 12 starters today? Not a positive direction that the league needs to be going. Are you concerned as we move into the summer?
RON HEMELGARN: As far as the league is concerned, any time you start a new league, it takes time to build momentum. You have cars that start out. They drop out because of financial problems and so on. I remember when we started Indy Lights back in the middle of the '80s, we had two cars going to Phoenix. There were four of us. I owned two of them. There were only four cars there. Pat Patrick and Roger Bailey had to drag cars out of the trailer just to put guys in to start the race. Actually we're further ahead than Indy Lights were back then. But it is hard. It's hard to find sponsors. It's hard to get teams. Obviously we need more of the IRL teams to get involved in that. As the program begins to build, I think you'll see more and more of those team comes in. I think that's what happened with the Indy Lights back then, when the IndyCar teams got involved, it started to change. It's part of the growing pains. Unfortunately, you lose some, you gain some. Gee, when you just think about the IRL itself, there's only three of us still running out here today from the original group that started the IRL. If we're going to go through that, I don't see anything changing in the near future. I think as time goes on, this will be a very valuable series, I think it will be a competitive series, and I think you'll see guys run this series, move up into the big cars. There's no question about that.
ARIE LUYENDYK, JR.: I think the depth of the field is much better than last year. I think last year, at the opener, we all saw 12 cars. If you look at the drivers in our series, it's very competitive. I think the talent level has stepped up a little bit. It's definitely the depth of it is much greater.
AARON FIKE: Not only that, our last race, we had our biggest field. Obviously, we had some carnage there. We took out probably five or six cars. I think definitely that's a factor, too.
Q. Aaron, I noticed that you got quite a busy itinerary coming up here. Do you always do this busy of a schedule, seven races in the next seven days?
AARON FIKE: It's about once or twice a year, you know, more like once a year actually. Iowa, sprint week, whatever you want to call it. We usually keep pretty busy, trying to run as much as we can in USAC, midgets. We've always been pretty busy. I ran probably 60, 70 races the last three years. I've gotten a lot of experience for my age. This program definitely helps me, too. I think running in as many different types of cars is good for you. You get the experience of running at all these different tracks.
Q. What is your itinerary going to be? Night race tomorrow?
AARON FIKE: Yeah. We shouldn't be too pressured to get there. My dad has his own plane. He's a great pilot.
AARON FIKE: Talked right through the middle of it. My dad goes, "Do you want to go left or right?" "Let's go left." Probably would have been in a tornado if we went to the right. I slept through most of it. I get in the plane and I just fall asleep. My dad is a really good pilot. I rarely ever get nervous in a plane.

redpajama_set_name: RedPajamaCommonCrawl


text:
«Янкі Дудл Денді» () — американський музично-біографічний фільм 1942 про актора, танцюриста, співака, драматурга, автора пісень, продюсера, хореографа, власника театру, режисера Джорджа М. Кохана, відомого як «Людина, яка володіє Бродвеєм».

Сценарій написали Роберт Бакнер і Едмунд Йосиф, фільм зняв режисер Майкл Кертіс. За даними спеціального видання DVD, значні поліпшення в сценарій внесли знамениті «лікарі сценаріїв» брати-близнюки Юлій Дж. Епштейн і Філіп Г. Епштейн, в титрах фільму вони не вказані.

Сюжет
Біографічний мюзикл, що розповідає про життя прославленого бродвейського актора, співака і танцюриста Джорджа М. Коена, автора патріотичних американських пісень. Картина побудована як ланцюг спогадів самого постарілого Коена про власне життя, починаючи з дня народження (4 липня 1878) до вручення нагороди з рук президента США за внесок у мистецтво. Це історія життя людини, який сам продюсував, писав і грав у своїх музичних шоу. Сцени дитячих виступів Джорджа, історію його співпраці з письменником і продюсером Семом Геррісом, реконструкцію фрагментів Бродвейских уявлень Коена. Це йому як теоретику американського мюзиклу належить знамените визначення жанру - «Ритм, ритм і ще раз ритм!».

У ролях
 Джеймс Кегні — Джордж Кохан
 Джоан Леслі — Мері
 Волтер Г'юстон — Джеррі Коган
 Розмарі ДеКамп — Неллі Коган
 Джинн Кегні — Джоссі Коган
 Ирен Меннінг — Фей Темплтон
 Річард Горф — Сем Гарріс

Нагороди
Оскар, 1943 рік, фільм переміг у номінаціях:
 Найкраща чоловіча роль (Джеймс Кегні)
 найкращий звук
 Найкращий саундтрек для музичних картин
Фільм був номінований:
 найкращий фільм
 Найкраща чоловіча роль другого плану (Волтер Г'юстон)
 Найкращий режисер (Майкл Кертіс)
 найкращий сюжет
 найкращий монтаж

Посилання

Фільми-драми США
Біографічні фільми США
Національний реєстр фільмів
Чорно-білі фільми
Фільми 1942
Фільми США 1942
Фільми Warner Bros.
Музичні фільми США
Фільми Майкла Кертіса
Фільми англійською мовою

redpajama_set_name: RedPajamaWikipedia


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In 1837 the Gooderham and Worts distillery went into business. It thrived and grew over the next few decades. In fact the site was a distillery until 1990 at which point it was abandoned and left to become derelict. In 2003 the site was renovated and re-opened as a collection of shops, galleries, studios, restaurants, cafes and theatres. Much of the original architecture remains.
Looking through a window. Is she looking out?


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IN THIS SITUATION, DIRTY WATER FROM THE HILLSIDE POOL WILL BACK-SIPHON OR BACK-FLOW DOWN THE HOSEPIPE AND INTO THE CLEAN WATER TANK. TO PREVENT THIS FROM HAPPENING, THE HOUSE'S EXTERNAL TAP SHOULD BE FITTED WITH A BACKFLOW PREVENTION DEVICE.
In many commercial applications, backflow prevention is required by municipal water authorities. They are often required whenever water from a main line is delivered to a water meter (to protect the meter), fire sprinklers, soft drink fountains, medical equipment, irrigation, cooling towers, and many other specialty applications.
The back flow prevention device is important in protecting health and welfare of the general public, because it prevents municipal water from being contaminated by contaminants and pollutants, such as: irrigation water, pesticides, cleaning agents, water conditioners for boilers, X-ray developer, fire supply lines, soda machines, etc.
What will happen if I don't use a backflow device, or if I don't have it tested?
Municipal water authorities, especially in and around LA County, take water backflow prevention seriously, and require devices be tested regularly. In fact, Water Districts are required by the EPA and the State of California to adhere to a Cross Connection Control Program.
If you are not in compliance with testing and prevention regulations, then your municipal water supply may be turned off. This could be detrimental to many businesses, so we recommend you keep up with scheduled and required testing.
How much does backflow testing cost?
We're offering backflow prevention device testing starting at just $68.


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text:
Hemel Hempstead 3
Welwyn Garden City 1
Hertford 1
Luton 3
Oxfordshire 2
Cherwell District 1
English jobs
English Teacher New
English Teacher - KS3-KS5 Location: Kingston Upon Thames Start Date: September 2023 We are looking for an outstanding English Teacher to join our successful, Ofsted-rated Good School in Kingston Upon Thames from September 2023. You will be a passionate teacher with the ability to engage and motiv...
English ECT New
We are currently seeking a English ECT to join our team in Braintree on a permanent basis. The role will offer an attractive salary of £30,000 - £34,000 per annum plus an induction programme to provide you with the necessary training and development needed for the position. The ideal candidate wi...
We are currently seeking a English ECT to join our team in Harlow on a permanent basis. The role will offer an attractive salary of £30,000 - £34,000 per annum plus an induction programme to provide you with the necessary training and development needed for the position. The ideal candidate will ...
We are currently seeking a English ECT to join our team in Chelmsford on a permanent basis. The role will offer an attractive salary of £30,000 - £34,000 per annum plus an induction programme to provide you with the necessary training and development needed for the position. The ideal candidate w...
We are currently seeking a English ECT to join our team in southend on a permanent basis. The role will offer an attractive salary of £30,000 - £34,000 per annum plus an induction programme to provide you with the necessary training and development needed for the position. The ideal candidate wil...
We are currently seeking a English ECT to join our team in Chigwell on a permanent basis. The role will offer an attractive salary of £30,000 - £34,000 per annum plus an induction programme to provide you with the necessary training and development needed for the position. The ideal candidate wil...
We are looking for an enthusiastic English Teacher to join our vibrant and ambitious school in Ilford. You will have the opportunity to inspire, engage and challenge our students to help them achieve their best potential. This is a permanent full-time post with a starting salary of £30,000-£41,00...
We are seeking an experienced and enthusiastic English Teacher in Maldon. This is a permanent position, commencing September 2023 with a salary range of £30,000-£41,000 (MPS/UPS) The successful applicant will have: -A passion for teaching English and the ability to inspire students; -PGCE/QTS or ...
We are looking for a highly motivated and experienced English Teacher to join our team. The successful applicant will teach a range of English and have a commitment to the continuous development of the subject area. The ideal candidate should have: - Excellent classroom management skills; - The a...
We are seeking an experienced and enthusiastic English Teacher in Harlow This is a permanent position, commencing September 2023 with a salary range of £30,000-£41,000 (MPS/UPS) The successful applicant will have: -A passion for teaching English and the ability to inspire students; -PGCE/QTS or e...
We are looking for an enthusiastic English Teacher to join our vibrant and ambitious school in Harlow, Essex. You will have the opportunity to inspire, engage and challenge our students to help them achieve their best potential. This is a permanent full-time post with a starting salary of £30,000...
English Teacher - Permanent Position, Start September 2023 We are looking for an enthusiastic and committed English Teacher to join our successful school in Southend. The successful candidate must have the necessary qualifications and enthusiasm to contribute to this highly-regarded school. The r...
We are seeking an experienced and enthusiastic EnglishTeacher in Ilford. This is a permanent position, commencing September 2023 with a salary range of £30,000-£41,000 (MPS/UPS) The successful applicant will have: -A passion for teaching English and the ability to inspire students; -PGCE/QTS or e...
Cherwell District
£30000 - £45000 per annum + MPS/UPS dependent on experience
We are seeking a full-time English Teacher with a real passion for the subject, to join an Ofsted 'good' 11-18 Academy in North Oxfordshire. In this role, you will have the opportunity to make an impact on the life chances and 'cultural capital' of young people by developing their academic litera...
Geography Teacher
£150 - £200 per day + Negotiable upon experience
Geography Teacher Required - Luton - ASAP Start We are looking for an enthusiastic and highly motivated Geography Teacher to join q school in Luton on a long term contract. The ideal candidate will have the ability to inspire and engage students in learning by demonstrating passion and enthusiasm...
Intervention Teacher
We are looking for an experienced and enthusiastic teacher to join our team in Luton as soon as possible, on a long-term contract basis. You will be working with Year 11 students delivering intervention teaching. Qualified Teacher Status (QTS) is essential. If you feel you have the skills and qua...
English Intervention Teacher
We are looking for an experienced and enthusiastic English teacher to join our team in Hemel Hempsted as soon as possible, on a long-term contract basis. You will be working with Year 11 students delivering intervention teaching. Qualified Teacher Status (QTS) is essential. If you feel you have t...
We are looking for an experienced Maths Teacher with Qualified Teacher Status (QTS) to join our team for a one term contract, starting on a flexible date. This position is available on both a part-time and full-time basis and offers up to £200 per day. The successful candidate will be responsible...
Intervention Teacher - English
£30000 - £44780 per annum + Negotiable depending on experience
Interventions Teacher - English We are looking for an enthusiastic and committed Interventions Teacher to join our Ofsted Good School based in Hemel Hempstead. The successful candidate will be working with small groups, 1-1 and in class intervention to help prepare students for their GCSEs. This ...


With just a few simple clicks, your business can sign up for e-Statements—a greener, more convenient and secure way to stay up to date on your financial life. To enroll, just log in to your Community Bank Online Banking account and follow the instructions you find there. e-Statements are better than traditional paper statements in every way.


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In the run-up to the Oscars, the voting season is currently at its peak, and all the awards make a rush to be announced now because of the hype surrounding their ability to possibly prejudice the voting jury.
So, with Academy Awards voting to be closed and finalised on February 22, another round of Movie and Television awards is always fun. And, in this particular ceremony, the actors themselves have cast the votes!
Here are the big winners from the Screen Actors Guild awards.
Jamie Foxx has been discovered this year as a potent acting force, something unsuspected from his humble comedic origins. Nominated for three SAG awards, for Redemption, Collateral and Ray, Foxx picked up a much-deserved Best Actor award for his fantastic Ray Charles portrayal in Ray.
The actor came on stage and sang for Ray Charles, talked about how the legendary musician had been such an inspiration, and thanked his director Taylor Hackford before acknowledging the profound influence Denzel Washington had on his career.
He has also won a Golden Globe for Best Actor for his performance in Ray.
Cate Blanchett won the Best Actress in a Supporting role for her performance in The Aviator, opposite Leonardo DiCaprio.
Design: Uday Kuckian | Photographs: Getty Images
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Yes it affects us too!
We have for better or worse run the company with a verbal agreement and standing by our word. With the enforcement of the GDPR coming into force on the 25th May, we have written terms and conditions that you will have to agree to, to continue to make use of our services. At the bottom of every page of the this site are the key documents, relating to terms of service and privacy.
At this stage any client who doesn't agree to these new term's is welcome to chat to negotiate special terms or to terminate there agreement (we hope you don't!) without the 30 days notice.
We will look after your client data as if it is our own. Our servers are held in the UK, and we will never distribute it to non third parties (except service partners) unless required by law.
We have completed a internal data audit, and have made sure that we have appropriate contracts in place with our suppliers to protect your privacy.
Data sharing – Whilst we may host your data, you still own it and are responsible for it under GDPR, to that end please make sure that you follow good GDPR Practice.
Website Hosting- Please be aware that any plugins that you add to your site may be moving data to locations out of our control. Please be very careful with which plugins you install.


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School of Information Commencement 2011
Campanile Esplanade
The commencement ceremony honors the class of 2011 with student speakers, keynote speaker Reid Hoffman, and presentation of the James R. Chen Awards.
Reception on the South Hall lawn immediately following the ceremony.
Keynote Speaker: Reid Hoffman
Reid Hoffman is a Silicon Valley-based entrepreneur, executive, and investor who has been integral to building many of today's leading Internet-based consumer technology businesses, including LinkedIn and PayPal. He co-founded LinkedIn and served as CEO for four years, and he served as executive vice-president and a founding board member at PayPal.
Hoffman is currently a partner at Greylock Partners, where his areas of focus include consumer Internet, enterprise 2.0, mobile, social gaming, online marketplaces, payments, and social networks. Hoffman likes to work with products that can reach hundreds of millions of participants that have network effects. He is an advisor to Groupon, a director at Zyna, Mozilla, Six Apart, and Kiva.org; and he is an angel investor in many Internet companies, includine Digg, Facebook, Flickr, Lastfm, Ning, Six Apart, and Zynga. Hoffman earned a master's degree in philosophy at Oxford, where he was a Marshall Scholar, and a BA in symbolic systems at Stanford University.
Reid Hoffman
(photo: Joi Ito)


Following strong returns in 2016 and 2017, global share markets had mixed returns throughout 2018. After a volatile start to the year, markets appeared to recover throughout June to September before sharper falls in the last few months of the year.
As the Growth (Cbus MySuper) option has around half its investments in shares, this has impacted the shorter term returns for this option and other Cbus investment options that have shares.
The share market falls in late 2018 have been a result of a few factors, including higher interest rates in the US after many years of very low rates, slowing global economic growth, an escalation in the US/China trade tensions and uncertainty about whether the UK will successfully exit the European Union. The global economic outlook for 2019 and 2020 is now less positive, and strong returns from share markets over the short to medium term seem unlikely.
The weaker returns from share markets in 2018 follows a couple of years of strong returns and these are reflected in Cbus' favourable longer-term results. While the recent period of falling share markets may be a concern for members, it is important to maintain a longer-term focus when considering superannuation. Periods of negative returns will occur from time to time and Cbus' investment options are designed with this in mind. In particular, they include a range of asset classes to provide more stable returns over the long term than investing in just shares.
Cbus has over 20% of the Growth (Cbus MySuper) option invested in unlisted property and infrastructure assets. These assets are expected to provide long term returns comparable with share markets but with less short-term volatility. Their returns tend to be more stable than shares because revenue for these assets typically reflect long-term contracts.


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Ben Jumonville Selected State Representative at Boys Nation
At Louisiana Boys State, Catholic High Senior Ben Jumonville was selected as one of two delegates to represent Louisiana at Boys Nation in Washington, D.C. from July 16-27.
Jumonville will join students from around the country and will participate in discussing legislation and current bills. He will also have the opportunity to meet President Obama, Congressmen, and to visit U.S. State Departments.
Jumonville was one of six students from Catholic High who attended Boys State. Others included Andrew Carmichael, Jae Labat, John Paul Luckett, Simon Cassel and Chris Focht. Luckett was selected State Attorney General.
'Upon going to Boys State, I was ready to be immersed in local politics and government. As the week went on and I became close with other Boys State delegates, I realized that this was an extraordinary group of people. With that in mind, it is a real honor to be chosen to represent not only Louisiana but also the 400 other 'citizens of Boys State' at Boys Nation,' commented Jumonville.
Jumonville is serving as president of Hi-Y and as a member of the Executive Board of Student Council. He is a member of National Honor Society, Mu Alpha Theta, Student Ministry and the wrestling team.
A graduate of St. Aloysius Elementary School, Jumonville is the son of Charles and Wendy Jumonville.


Humanity is undergoing essential changes in various fields of life, such as material development and political, social, moral and transformations. With that the good news is over. The solutions mentioned, continuously cause new problems, a part of which become the problem of the following development cycle and the other part is simply ignored, or regarded as an unavoidable by-product. This is intensively felt in the environmental impacts caused by the industrial revolution and the depletion of natural resources. In the eyes of the children of future generations we are prehistoric men, technically brilliant primitives who ate, drank and breathed their own garbage. Waste and garbage means a lack of imagination, these words will only be familiar from history books. After the Neolithic age and the industrial-technological revolution, the beginning of the third energy revolution was a necessary consequence: the current post-fossil episode. As 50% of the world's energy and material consumption is generated in the construction industry, architects must bear great responsibility. A new interdisciplinary workshop-based training program has been added to the architecture and engineering training at Pollack Mihály Technical Faculty, University of Pécs, organised by the Ecological Organic Technologies Studio. Differences between conventional and energy designed buildings can be described by using the ingenious ship analogy: With help of an engine practically all floating objects can be transformed into a steerable ship. A small sized compact mechanical device transforms a raw form into a functional object-oriented work of art. A building is not to be considered any longer as a box fulfilled with technical apparatus but it should be developed into a 'climate machine' which – just like a sailing boat – dynamically responds to environmental impacts and supplies itself using local energy sources.


At the first day of the Intel Developer Forum in San Jose, Sonicblue showed off a co-designed prototype intended to do for video what portable MP3 players have done for music.
The unnamed unit, around 25 by 10 by 5 centimetres in size, has a four-inch colour LCD screen, a 20GB PC Card hard disk and lithium batteries: it loads movies through USB 2.0 or Ethernet and integrates closely with the company's Replay TV hard disk personal video recorder. As well as playing backup to 70 hours of video from the internal hard disk onto the LCD screen, the portable unit connects to an external monitor or TV.
"We'll be concentrating on getting the first model right," said Mikhil Balram, VP of Connected Home at Sonicblue, "and then we'll do price-performance." He added that as the unit could also play still pictures and MP3 music, it was better to think of it as a portable media player.
Based around Intel's XScale processor and using Intel's video software on the Microsoft Windows CE operating system, the first production units are due sometime in 2003 and are expected to cost "less than $1000 (around £640), but we'll put the price up rather than compromise the first product," said Balram. The company was considering adding FireWire, but had no plans for models that worked with European television standards. Battery life was currently around four hours, but this is not going to be typical of the final product.
A handful of prototype units were on display at the launch, showing movie clips, captured TV and other content.
The quality of the display, with its very high contrast and saturated colours, more than compensated for the small size of the unit. Sonicblue says that despite its pocket dimensions, the unit will be enjoyable to watch for many hours at a time, and this seems highly possible. The experience of playing with one is seductive: although there is no reason why similar features couldn't be included in personal digital assistants or portable game consoles, the simplicity and convenience of portable video players may make them into a very desirable gadget in the years to come.
Rupert Goodwins reported from San Jose.


When we first got orders to Miami I was sure that we were the luckiest Army family in the world. I mean what's not to like about palm trees and beaches? Plus, how many people in the Army actually get a duty station like this? It was a miracle! We counted down the months, drooled over the BAH amount (before we realized how expensive it was to live here ) and in September we hurried on our way to Miami for early report..The Redmonds were going south for the winter! Then we arrived in the city of Cuba (I mean Miami) and I realized that the grass was not as green as it looked from Missouri. It took me 7 months to learn how to fall in love with my new duty station (Don't roll your eyes) and I am here to help you not waste time and begin falling in love with yours.
The most important way to fall in love with your duty station is having a positive attitude and being optimistic about the new adventure. There are absolutely some duty stations that are better than others but a duty station is truly only as good as you make it. There will be some things that you love and some that you can do without everywhere you go. If you remember this step and go into the move with a great attitude, you're already half way there.
Start a Bucket List BEFORE you arrive!
One of the things that gets me super excited before we move or go on vacation is Pinterest! Pinterest is my all time favorite app because you can literally look up every destination and find a list of things to do, eat, or see. Even if you think that you are moving somewhere with nothing around, I guarantee you that you can find something to get into. After I got out of my PCS blues, I made a bucket list for things up to 2 hours away and we have been crossing things off the list every chance we get. Not only does a bucket list get you excited about being at a duty station but when you leave you will feel like you truly took full advantage of what the city had to offer and made amazing memories.
One thing that I did before we PCS'd was reach out to the Facebook groups and pages. They are an excellent way to meet new friends ahead of time so you won't feel as lonely when you arrive. You can also ask questions about the duty station like: Where should we live? How is traffic? What are the pros and cons? All you have to do is type in the duty station in the Facebook search bar or call the ACS building to ask for a list of official Facebook pages.
One thing that really grinds my gears are spouses who complain about not liking a duty station or not having friends when they haven't left their home to change that. It is up to you to get out there to be involved and meet new people. The groups that I told you about above offer information about upcoming events most of the time. You can even contact the FRG leader if you have one. I am not saying that you have to attend everything but making an effort to attend a spouse meet up or FRG meeting is a start!
If you're getting ready to PCS I know that it can be a scary and stressful experience but remember that the years are short and the memories are endless. Try to make each move the best 2 to 3 years of your life and that is how you fall in love with your new duty station.
Click HERE to read more military related content !
Great suggestions! I especially like the creating a bucket list and giving yourself things to look forward to.
Thanks for reading! Yes, bucket lists are fool proof ways to get excited about a new experience.
Heyyy! I just found you on Pinterest and immediately had to follow! We're also Army, but we're originally from Miami! Great suggestions in your post!
Aww Thank you so much for following. I love meeting other military spouses! We live in Miami now but we are originally from Atlanta. Thanks for reading.


Prashant Bhushan had called Alok Verma's appointment illegal, now he is calling his removal from office illegal too.
Amidst the ongoing battle between two factions of the CBI, the government of the day, citing ongoing investigations, has sent both the officers involved Rakesh Asthana and Alok Verma on leave. But this has not gone down well with some of the known Modi Government detractors.
According to the SC lawyer Prashant Bhushan, the BJP government removed Alok Verma from his office as he was pursuing corruption charges on Special Director CBI Rakesh Asthana. Bhushan also alleged Asthana's involvement in the Rafale deal was the reason for the government's alacrity to protect him from Verma's investigation.
The government had already claimed that they have sent both the officers on leave. In the meanwhile, the government has appointed senior IPS officer M Nageshwar Rao, a joint director within the CBI to take over the duties and functions of CBI Director with immediate effect. This decision comes soon after it was reported that Asthana and Verma had both been summoned by the Prime Minister.
If this wasn't enough, Prashant Bhushan has insinuated charges of corruption against M Nageshwar Rao and called him a tainted officer.
But this didn't go down well with an aware Twitter user (@iAnkurSingh), who took it upon himself to out Prashant Bhushan's shameless hypocrisy.
Prashant Bhushan went to SC agnst appointment of Alok Verma as CBI chief saying it's 'illegal' and he was placed by Modi govt to protect the Corrupt.
As outed by Ankur, it can be seen that Prashant Bhushan, in the past, had moved to the Supreme Court terming appointment of CBI Chief Alok Verma as 'illegal'. The SC had then quashed Bhushan's petition and refused to interfere in his appointment. Bhushan had also insinuated that Alok Verma was appointed by the Modi government to protect the corrupts.
Today, Prashant Bhushan is vehemently protesting against the government's move of asking Alok Verma to proceed on leave. One cannot help but wonder what motivates Prashant Bhushan to take such diametrically opposite stance in just over 20 months. From calling Alok Verma's appointment as 'illegal' to his ouster as 'illegal', Prashant Bhushan's flip-flops have sent his followers in a tizzy. It also testifies that Bhushan's only aim is to stop Modi, even if it comes at the cost of being exposed as a churlish hypocrite.
In the past too Prashant Bhushan has been accused of sharing fake news from dubious sources just to sustain his campaign against the Modi government. When the veracity of the news was outed, he quietly deleted his post without tendering an apology. This has become a pattern now. Prashant Bhushan has attempted to spread misinformation and half-baked allegations several times in the past. He had alleged recently that PM Modi had arranged for Mehul Choksi's Antiguan citizenship. He had also circulated a 'news clip' that claimed that Mukesh Ambani led Reliance Jio has bought 30 crores phones from China and it is a big scam. Both his claims were wrong.
In a massive setback for the Congress leadership, senior Congress leader Ahmed Patel, a close aide of the Sonia Gandhi has decided not to contest fearing a loss amidst a serious internal rift within the Gujarat unit of the party.


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Staff Feature: Principal Feuerherd
As someone who grew up, attended school and returned to teach in Anne Arundel County, Principal Kathryn Feuerherd said she is excited to use her knowledge and expertise to lead the brand new Crofton High School. She grew up in Linthicum, attended Linthicum Elementary School, Brooklyn Park/Lindale Middle School, and North County High School. She then went on to receive her undergraduate degree from Hood College and her master's degree from McDaniel College.
Principal Feuerherd started working for AACPS in August of 2003. She worked for 13 years at Old Mill High School as a Social Studies teacher and department chair. She went to work at Southern High School as the principal from 2016-2019. When offered the job she was thrilled for the opportunity to be principal at Crofton High School.
She said she feels as though "being the principal of a brand-new high school is a once in a career experience." According to Principal Feuerherd, one of the most appealing aspects was, "To be able to contribute to the culture, traditions, and learning environment from the start." She wanted to be a principal because " Throughout my career, I've always valued and appreciated the impact that a key leader can have on others." She believes that "Contributing to the culture, traditions, learning environment, opportunities available to students, etc. and seeing the success of our students beyond high school is one of the most rewarding components of the role."
The inaugural year at Crofton High School was far from what anyone thought it would be, but Principal Feuerherd shared that "while online/hybrid learning was definitely not what we anticipated this school year when we were planning last year, I am tremendously impressed with the relationships that have been built in each classroom, the instructional strategies and learning that takes place every day, and being able to finally see students accessing their brand new school."
As she talked about before, this year has not been easy or what anyone anticipated but she is "very proud of the opportunities that we have been able to provide to our students this school year – not just in the classroom, but the variety of clubs and extracurricular opportunities that are available, including opportunities for student participation in our book study as well as in our Equity Leadership Council."
She said she feels like "Our students have experienced remarkable accomplishments through service learning opportunities, with activities such as the Special Olympics Cool Schools Plunge and inclusion events through Best Buddies and Unified Sports. It has been amazing to see the level of student involvement in this very non-traditional school year!"
Mrs. Feuerherd shared that she has "twin 14-year old girls so when not working, you'll most likely find me at one of my daughters' sports practices or games or piano lessons. When we really have some "downtime," I really enjoy the outdoors – spending time on our deck/patio or at the beach, gardening, or reading." As for sports "Any Baltimore team is my favorite – the Orioles for baseball season and the Ravens for football season." She has a Labrador Retriever and is considering getting another dog this summer.
Science Department Chair Adam Swetz had amazing things to say about Principal Feuerherd. He shared that "She has a clear vision for the school and truly values each person that works for her. She is professional and knowledgeable." She is also "committed to giving everyone a voice. She has involved everyone in the decision-making process."
English Department chair Ms. Becca Bittman said she feels the same way. She said, "Her philosophies align with a lot of mine as well as the other staff and she is really making this an inclusive place. She uses her teacher's knowledge and expertise to guide decisions." Ms. Bittman also shared that she "recognizes the fact that we are putting lots of different school cultures together" because we are a brand new school, and "she really works to make both staff and students feel like you are a Crofton Cardinal like this is our community now."
During this school year, it may have been hard for people to feel like they are a part of a community given the fact that we had to be separate for most of it but now that school has been in person for over 2 months Principal Feuerherd said she is "looking forward to when we are able to have all of our students in the building five days per week. Once everyone is back in person we will be able to really come together as a Crofton High School community."


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Women Play Lacrosse Book
A new book on the history of international women's lacrosse will be launched during the FIL U19 Women's World Lacrosse Championships in Edinburgh, Scotland. Women Play Lacrosse – A History of the International Field Game is the first book to capture the 125 plus years of history in women's field lacrosse.
Co-authors Jim Calder and Ron Fletcher have compiled stories on some of the most important players, builders and moments in the women's game. Calder says, "We brought most of our team back from the highly successful Lacrosse – The Ancient Game and the culmination of three years of work is sure to be of great interest to all lacrosse enthusiasts."
A shortlist of material covered in the new work includes: the game's early beginnings throughout the British Empire, structure and direction provided by England, early touring on both sides of the Atlantic, survival of the game through WWII, a look at some of the most famous post-war tours, Title IX and the emergence of the USA as the world power, the creation of world championships and expansion of the game to nations such as Australia, Canada, Japan and the Haudenosaunee.
Readers will get the inside story on some of the international stars and builders of the game. They'll receive a comprehensive look at the organizations and rules that have governed the amazing growth.


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Home>Bio
An quartet of misfits thunderously tempting fate to boom their way across Big Texas and beyond at the speed of sound. By way of Dallas/Fort Worth, Texas comes one raucous TEMPTRESS.
Kelsey Wilson (Lead Guitar/Vocals), Andi Cuba (Drums/Vocals), Erica Pipes (Rhythm Guitar/Vocals), and Christian Wright (Bass/Vocals) all decided to get together in mid-January 2019, for a simple afternoon of rocking out with the intent for nothing more than keeping their skills sharpened. They weren't planning to be a band. It just worked.
In five months, these four seasoned players went from jamming for fun in a practice space, to writing and recording some potent heavy metal songs and then began performing them live as TEMPTRESS, with the likes of Heavy Temple, Wo Fat, Stonecutters, Ecstatic Vision and Royal Thunder.
On June 7th 2019, they presented their first three original songs in a debut EP release, 'Temptress'. The EP is available now via Bandcamp and most music outlets for digital download and streaming
https://ffm.to/nmov7ez
TEMPTRESS:
Kelsey Wilson – Lead Guitar/Vocals
Andi Cuba – Drums/Vocals
Erica Pipes – Rhythm Guitar/Vocals
Christian Wright – Bass/Vocals
Facebook | Instagram | Twitter | Tumblr
Bandcamp | Spotify | YouTube | Amazon | Deezer | iTunes
"With a sound as big as the state they hail from this Dallas/ Ft. Worth quartet throws down some grooving heavy riffs, swirling solos perfectly paired with drums and bass that are heavy, huge and just ooze with power." ~ Outlaw Review
"…an exercise in turn-it-up-'til-your-ears-bleed thundering party excess. A little bit of Motorhead here, some Girlschool and Montrose there, topped off with a pinch of doom and a cavalier punk rock attitude and wink, the Dallas, Texas unit have come up with a wildly entertaining concoction. I just keep hitting repeat over and over again once the three-track, 13-minute release concludes. One of the best EPs of the year." ~ The Mighty Decibel
"Temptress kick ass and take names on their balls-out barnburner Hot Rails, a taste of their self-titled June 7 EP. Hold on for dear life." ~ Tinnitist
"Ripping full-speed out of the gate with straight forward heavy rock 'n roll and traditional heavy metal, TEMPTRESS isn't wasting any time and they sure as hell don't strike me as a band that even knows the meaning of 'timid'." ~ Riff Relevant
"Amazing is the format that the band TEMPTRESS radiates on their first three-tracker, captivating the honest and easy way in which the band practices their sound. The three songs grow with each passage, offering smoky, fervently tuned melodies and a good portion of feeling." ~ KOBZR Magazine


What are the Distracted Driving Laws in New Jersey?
Distracted driving creates problems for everyone. From 2010-2014, it contributed to over 817,000 accidents in New Jersey. If you have been injured in an accident due to someone else driving while distracted, your lawyer can help you properly introduce that into evidence to show the driver was at fault.
Any of these behaviors can lead to substantial fines, as well as points and license suspension.
These penalties stem from the seriousness with which New Jersey treats the problem of driving while distracted. If the other driver is convicted, this should serve as evidence in your favor.
New Jersey has placed a limit on evidentiary use of convictions. A driver who pleads guilty to a traffic offense can apply for a civil reservation, which prevents you from using the guilty plea as evidence of fault in your accident. A skilled attorney will help you establish the fact of the distraction, even if you cannot use the conviction itself as evidence. If you know the other driver was distracted, you can establish that in court to help show fault.
Distracted driving creates unnecessary dangers in New Jersey and everywhere in the country. If another driver's distraction caused you a serious injury, contact Stern & Stern LLP so we can help you get the recovery you deserve.


Pain on right side of my head;which effects my temple,top of skull,right cheek,pain and pressure on back side of sinusand around eye. Feeling as thoughi cant get something unclogged from my sinus and needing to swallow a huge snot clog had a siezure 11 months ago and since space out alot(didnt relize until i made dinner and put wrong thing into something and relized after i finished) family doctor had mri w/c 10 months ago which showed nothing ,went to ent who said there was no sign of infection and my sinuses were clear ordered at ct w/c which showed a small cyst in left maxillary(no pain on left side of head),calibar of the ostiomeatal units are smaller than usually seen,and right maxillary is greatly largerthan left. I am now being told by ent that he cannot help and has sent me to neurologist,who i have an appointment with in two months,thepain and pressure has become horrible i want to stick somthing into throat to just try to relieve pain,and scared of spacing out with not knowing if and when it happens I am not sure of what to do this is new and i havenever had these problems before i never had headaches in my life.what could this be?


British investors appear well ahead of many of their Asian peers on employing environmental, social and governance concepts, particularly in respect of climate risk.
Sustainable investing is becoming more popular in Asia, but it has gained even more momentum in the UK, with a particular focus on climate change risk.
With so much money piling into unlisted debt, attention is now turning towards what might happen when the credit cycle turns, and what investors can do to tackle liquidity challenges.
Defined-benefit pension funds in the UK are cutting equity positions in the active space, but adding private debt in their hunt for alpha.
Asian pension funds should keep an eye on big changes taking place in the UK's retirement industry, including a portfolio de-risking trend and a rising focus on cashflow-driving investing.


How Did We Get Into This Mess?: What's Going On At InBev?
Yesterday, Pacific Standard published a piece of mine on medieval brewing and lack of gender diversity at Google. I mostly talked about medieval history and the Bennett-thesis on patriarchal equilibrium. But as I reached the end of the draft, I started doing a little research into contemporary brewing, tipped off by a friend that there had been a lot of comment about gender and craft beer.
Back to brewing—the craft beer revolution of the last few decades has provided opportunities for women to enter the industry, despite the modern cultural associations of beer with manliness. The Pink Boots society, an organization dedicated to supporting women in the beer industry, has been growing over the last decade. But patriarchal equilibrium is rearing its head in that industry as well, not because individual men are driving out individual women, but because Big Beer is attacking Craft Beer. Right now, Anheuser-Busch InBev, the beer giant, is purchasing craft breweries. There's not a single woman on its management team.
It's important to identify and work against individual acts of discrimination. The gender consequences of InBev offer another way to look at the big picture of gendered (and other forms of) discrimination.


Although the cross-border engagements of immigrants have received an increasing attention since the 1990s, the role of migrant organisations in this process has spurred comparatively little interest. As a consequence, efforts to conceptualise migrant organising in the transnational sphere have been relatively scarce. This paper seeks to contribute to this effort by proposing a more systematic definition and use of the concept of transnational organisational fields. This endeavour is illustrated by two case studies based on research carried out within the TRAMO project (Diffusion and Contexts of Transational Migrant Organisations): Indian and Polish organisations in the UK. The intent is to show that much can be gained by adopting a bird's-eye view on the networks that bind together migrant organisations within and outside the country of settlement. The two case studies display two opposite forms of structuring. In the Polish case, the formation of the field was managed by a central institution (the Polish government in exile) while, in the Indian case, there was a decentralised process. These discrepancies have consequences on the shape and contents of cross-border activities of migrant organisations.


To render unconscious by anesthesia, as during a surgical procedure. Your daughter is doing great. We put her under with no issues, and the surgeon is operating now. I've never had surgery before, and I'm really nervous for when they put me under—what if I don't wake up?
to place someone or something beneath something. Dave put Sam under the loft in the barn, hoping no one would find him there. Alice put the birthday present under the couch, where she could get to it in a hurry.
Fig. to anesthetize someone. They put him under with ether. After you put her under, we will begin the operation.


Shooting Lives, led by Tapan Parikh, is a team of wedding photographers based in Vadodara. The team, which captures the golden moments of your big day, also travels to other cities, making it an ideal choice for outstation and destination weddings.
Shooting Lives is a Wedding Photographer based out of Baroda . Shooting Lives's telephone number is 76-66-77-88-99, address is Vadodara, Gujarat, India.
In terms of pricing Shooting Lives offers various packages starting at Rs 150000/-.
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32 informational cards about the traditional iconography of Quechua textiles!
BRAND NEW to the Threads of Peru product line, the "wisdom cards" sets will be your guide to the high Andes and its ancient iconography. Each of these 32 cards features a different traditional design of the Cusco region with its Quechua name, meaning and a suggestion for meditation.
Even our team has been surprised and delighted by this little known information!
WHO MADE THE WISDOM CARDS?
The idea behind the Wisdom Cards was to share the wisdom of the Andean weavers, not only for their aesthetic complexity, but also their reflective properties.
In 1947, Doctor Delia Vidal de Milla of Cusco began an investigation in various high Andean weaving communities. She had already observed that the women of the Andes did not follow guides or patterns, and that each textile was her unique inspiration.
During her research, the women explained that their weaving was done in a state of silence and meditation, and the symbols they used had special meanings related to those hours of reflection.


Home LIFESTYLE FOODIE Our Favorite Foodie Finds to Dine at for NYC Broadway Week!
NYC Broadway Week is slowly upon us, beginning on September 4th and going right into September 17th. The alternative to Restaurant Week, NYC Broadway Week highlights the best deals to see some of your favorite shows and get a first glimpse of how amazing our city is in the fall weather. However, you still have to eat, and luckily there are a couple of great spots neighboring these iconic theatres that you must try while you are here or just taking the subway to see these award winning shows.
Check out these spots for NYC Broadway Week, and for more information, click here.
Native New Yorkers, tourists, and celebrities alike can't get enough of the legendary restaurant's heaping plates of Italian eats. Sure to make everyone in the family happy and full without breaking the bank, family-style portions of classic dishes include Spaghetti and Meatballs, Seven Layer Lasagna, and Chicken Parmigiana. More info here.
Don't be surprised to find authentic barbecue eats in the heart of Times Square, as Virgil's has been showing the city Southern hospitality for over 20 years. Whether you're looking to sip on a Frozen Margarita or dig into finger-licking BBQ Wings and Carolina Pulled Pork, you'll be sure to leave satisfied. More info here.
If you're Broadway fan, you'll be a Schmackary's fan, as the duo goes together like milk and cookies! The creative cookie bakery with a rotating menu of over 75 flavors and counting such as Cereal Killer, Sch'mores, and Maple Bacon, it's the perfect place for a sweet indulgence. Often sighted in between shows and during last night snacking are the stars themselves! They are also offering a special treat for fans of Broadway's Charlie And The Chocolate Factory. The Golden Ticket Bar (6 pieces for $19.50, one dozen for $35) is made with a shortbread cookie crust, sticky cookie butter and caramel filling, topped with dark and white chocolate ganache, exclusively available at the bakery and for local delivery. More info here.
This sleek Japanese-Peruvian restaurant is the glamorous new restaurant to add to your pre-theater dining list. Sit at the high top tables in the bar, restaurant, or at the sushi bar and order grilled skewers of meat and vegetables (like a half-grilled avocado with onion slaw) and sushi from their midday menu from 3-5pm, or stay for dinner after 5pm for ceviches and Japanese-Peruvian main dishes like Salmon with Miso Cheese and Maitake Mushroom. Post-show, head over for an infused Pisco cocktail nightcap and fun appetizers in the bar! More info here.


text:
package net.opengis.citygml.relief.provider;

import java.util.Collection;
import java.util.List;

import net.opengis.citygml.building.provider.CityGMLEditPlugin;

import net.opengis.citygml.relief.GridPropertyType;
import net.opengis.citygml.relief.ReliefPackage;

import net.opengis.citygml.texturedsurface.TexturedsurfacePackage;

import net.opengis.citygml.transportation.TransportationPackage;

import net.opengis.citygml.vegetation.VegetationPackage;

import net.opengis.citygml.waterbody.WaterbodyPackage;

import net.opengis.gml.GmlFactory;
import net.opengis.gml.GmlPackage;

import net.opengis.gml.provider.AssociationTypeItemProvider;

import org.eclipse.emf.common.notify.AdapterFactory;
import org.eclipse.emf.common.notify.Notification;

import org.eclipse.emf.common.util.ResourceLocator;

import org.eclipse.emf.ecore.EStructuralFeature;

import org.eclipse.emf.ecore.util.FeatureMap;
import org.eclipse.emf.ecore.util.FeatureMapUtil;

import org.eclipse.emf.edit.provider.IEditingDomainItemProvider;
import org.eclipse.emf.edit.provider.IItemLabelProvider;
import org.eclipse.emf.edit.provider.IItemPropertyDescriptor;
import org.eclipse.emf.edit.provider.IItemPropertySource;
import org.eclipse.emf.edit.provider.IStructuredItemContentProvider;
import org.eclipse.emf.edit.provider.ITreeItemContentProvider;
import org.eclipse.emf.edit.provider.ViewerNotification;

import org.w3._1999.xlink.ActuateType;

/**
 * This is the item provider adapter for a {@link net.opengis.citygml.relief.GridPropertyType} object.
 * <!-- begin-user-doc -->
 * <!-- end-user-doc -->
 * @generated
 */
public class GridPropertyTypeItemProvider
	extends AssociationTypeItemProvider
	implements
		IEditingDomainItemProvider,
		IStructuredItemContentProvider,
		ITreeItemContentProvider,
		IItemLabelProvider,
		IItemPropertySource {
	/**
	 * This constructs an instance from a factory and a notifier.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	public GridPropertyTypeItemProvider(AdapterFactory adapterFactory) {
		super(adapterFactory);
	}

	/**
	 * This returns the property descriptors for the adapted class.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	public List<IItemPropertyDescriptor> getPropertyDescriptors(Object object) {
		if (itemPropertyDescriptors == null) {
			super.getPropertyDescriptors(object);

		}
		return itemPropertyDescriptors;
	}

	/**
	 * This specifies how to implement {@link #getChildren} and is used to deduce an appropriate feature for an
	 * {@link org.eclipse.emf.edit.command.AddCommand}, {@link org.eclipse.emf.edit.command.RemoveCommand} or
	 * {@link org.eclipse.emf.edit.command.MoveCommand} in {@link #createCommand}.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	public Collection<? extends EStructuralFeature> getChildrenFeatures(Object object) {
		if (childrenFeatures == null) {
			super.getChildrenFeatures(object);
			childrenFeatures.add(ReliefPackage.Literals.GRID_PROPERTY_TYPE__RECTIFIED_GRID_COVERAGE);
		}
		return childrenFeatures;
	}

	/**
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	protected EStructuralFeature getChildFeature(Object object, Object child) {
		// Check the type of the specified child object and return the proper feature to use for
		// adding (see {@link AddCommand}) it as a child.

		return super.getChildFeature(object, child);
	}

	/**
	 * This returns GridPropertyType.gif.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	public Object getImage(Object object) {
		return overlayImage(object, getResourceLocator().getImage("full/obj16/GridPropertyType"));
	}

	/**
	 * This returns the label text for the adapted class.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	public String getText(Object object) {
		ActuateType labelValue = ((GridPropertyType)object).getActuate();
		String label = labelValue == null ? null : labelValue.toString();
		return label == null || label.length() == 0 ?
			getString("_UI_GridPropertyType_type") :
			getString("_UI_GridPropertyType_type") + " " + label;
	}

	/**
	 * This handles model notifications by calling {@link #updateChildren} to update any cached
	 * children and by creating a viewer notification, which it passes to {@link #fireNotifyChanged}.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	public void notifyChanged(Notification notification) {
		updateChildren(notification);

		switch (notification.getFeatureID(GridPropertyType.class)) {
			case ReliefPackage.GRID_PROPERTY_TYPE__RECTIFIED_GRID_COVERAGE:
				fireNotifyChanged(new ViewerNotification(notification, notification.getNotifier(), true, false));
				return;
		}
		super.notifyChanged(notification);
	}

	/**
	 * This adds {@link org.eclipse.emf.edit.command.CommandParameter}s describing the children
	 * that can be created under this object.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	protected void collectNewChildDescriptors(Collection<Object> newChildDescriptors, Object object) {
		super.collectNewChildDescriptors(newChildDescriptors, object);

		newChildDescriptors.add
			(createChildParameter
				(ReliefPackage.Literals.GRID_PROPERTY_TYPE__RECTIFIED_GRID_COVERAGE,
				 GmlFactory.eINSTANCE.createRectifiedGridCoverageType()));
	}

	/**
	 * This returns the label text for {@link org.eclipse.emf.edit.command.CreateChildCommand}.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	public String getCreateChildText(Object owner, Object feature, Object child, Collection<?> selection) {
		Object childFeature = feature;
		Object childObject = child;

		if (childFeature instanceof EStructuralFeature && FeatureMapUtil.isFeatureMap((EStructuralFeature)childFeature)) {
			FeatureMap.Entry entry = (FeatureMap.Entry)childObject;
			childFeature = entry.getEStructuralFeature();
			childObject = entry.getValue();
		}

		boolean qualify =
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Definition() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_UnitDefinition() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_BaseUnit() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_CartesianCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_CompoundCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_ConcatenatedOperation() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_ConventionalUnit() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Conversion() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_CoordinateSystemAxis() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_CylindricalCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_DefinitionProxy() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_DerivedCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_DerivedUnit() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_DefinitionCollection() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Dictionary() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_EllipsoidalCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Ellipsoid() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_EngineeringCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_EngineeringDatum() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_GeocentricCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_GeodeticDatum() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_GeographicCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_ImageCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_ImageDatum() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_LinearCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_ObliqueCartesianCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_OperationMethod() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_OperationParameterGroup() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_OperationParameter() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_PassThroughOperation() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_PolarCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_PrimeMeridian() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_ProjectedCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_SphericalCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TemporalCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TemporalCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TemporalDatum() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TimeCalendarEra() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TimeCalendar() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TimeClock() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TimeCoordinateSystem() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TimeOrdinalReferenceSystem() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Transformation() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_UserDefinedCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_VerticalCRS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_VerticalCS() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_VerticalDatum() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_DirectedObservation() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Observation() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_DirectedObservationAtDistance() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Grid() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_RectifiedGrid() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_OrientableSurface() ||
			childFeature == TexturedsurfacePackage.Literals.DOCUMENT_ROOT__TEXTURED_SURFACE ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_PolyhedralSurface() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Surface1() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_TriangulatedSurface() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_Tin() ||
			childFeature == GmlPackage.eINSTANCE.getDocumentRoot_RectifiedGridCoverage() ||
			childFeature == ReliefPackage.Literals.GRID_PROPERTY_TYPE__RECTIFIED_GRID_COVERAGE ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__TRANSPORTATION_OBJECT ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__AUXILIARY_TRAFFIC_AREA ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__TRANSPORTATION_COMPLEX ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__RAILWAY ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__ROAD ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__SQUARE ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__TRACK ||
			childFeature == TransportationPackage.Literals.DOCUMENT_ROOT__TRAFFIC_AREA ||
			childFeature == VegetationPackage.Literals.DOCUMENT_ROOT__VEGETATION_OBJECT ||
			childFeature == VegetationPackage.Literals.DOCUMENT_ROOT__PLANT_COVER ||
			childFeature == VegetationPackage.Literals.DOCUMENT_ROOT__SOLITARY_VEGETATION_OBJECT ||
			childFeature == WaterbodyPackage.Literals.DOCUMENT_ROOT__WATER_OBJECT ||
			childFeature == WaterbodyPackage.Literals.DOCUMENT_ROOT__WATER_BODY;

		if (qualify) {
			return getString
				("_UI_CreateChild_text2",
				 new Object[] { getTypeText(childObject), getFeatureText(childFeature), getTypeText(owner) });
		}
		return super.getCreateChildText(owner, feature, child, selection);
	}

	/**
	 * Return the resource locator for this item provider's resources.
	 * <!-- begin-user-doc -->
	 * <!-- end-user-doc -->
	 * @generated
	 */
	@Override
	public ResourceLocator getResourceLocator() {
		return CityGMLEditPlugin.INSTANCE;
	}

}

redpajama_set_name: RedPajamaGithub