Territory Management is one of the most important elements of running a business whose workforce tends to operate on an 'out of office' basis. Moreover, the fundamentals of territory creation and management remain the same whether you are building territories for sales teams or field service engineers for refuse collection routes or newspaper deliveries. Territories must enable efficient workforce productivity, allowing your staff more time spent onsite and less time spent travelling.
The territories used by the majority of businesses today tend to be based on legacy rules and principals passed on by previous managers and directors, and are often built on subjective views, internal politics or historic customer allocations. This can lead to some field force representatives having large or disparate geographic areas to cover.
Our contemporary approach to territory management and optimisation utilises mathematical algorithms to build territories based around one or more criteria. Your organisation should be able to choose how to build territories around your existing representative locations for the best possible shapes and sizes of territory. This approach can lead to significantly more balanced territories with reduced drive-times, allowing your on-site staff more time with customers and accounts. Build solutions on essential locational data detailing street level road networks, road speeds or public transport scheduling for the country in question.
Prioritising specific customers over others also allows you to build in the most appropriate levels of face time. Sort your customers by their strategic importance, using categories such as 'Strategic Account', 'National Account', 'Key Account' and 'Standard Account'.
The regularity with which your field forces visit accounts varies depending on the industry your organisation operates in. Some could be fixed full account rotations on a monthly to 6-week basis for certain sales activities, whereas field service engineers operating in facilities maintenance may be on 3-month, 6-month or yearly cycles depending on the infrastructure they are working on.
Rigid call plans don't always work if your accounts require face-to-face meetings with specific people, meaning that call planning should sometimes act more as a guide rather than a rigid set of rules. Planning for Preventive Maintenance (PPM) can be effective if access to plant and infrastructure is limited however. This not only enables your workforce to prepare more effectively for jobs in advance, pre-ordering any inventory required to undertake this task, but from a management perspective, this can allow you to better organise your planned working hours, distances travelled, mileage and gear.
The allmapdata Geosolutions Team at CACI are experts in territory management, helping a wide variety of organisations optimise door-drop delivery rounds, depot areas, franchises and merchandiser territories, for example.
Geoconcept GIS and Geoxploit provide map analysis solutions, with the latter including pre-configured data to make it easy to analyse demographics, optimise territories, calculate drive times and much more. Exploit these strategic insights to pitch your services and products to your customers correctly.
Now that the whole process is managed within a GIS provided by allmapdata, it's much easier to make changes on the spot. For instance, if I'm on the phone to a franchise-holder, and they explain that it would make sense to amend some detailed aspect of the territory boundary, then providing the change doesn't have any adverse impact on an adjacent territory, I can make the change there and then. I could never have done that with the old system.
Call us now on +44 (0)20 8568 7000, email us or fill in the form to book a demonstration and to discuss your Territory management requirements.
Professional consultancy helping you implement your chosen territory management solution or undertaking the work for you to create optimised territories and rounds that balance the criteria you specify.
Territory Manager automatically generates territories for sales staff, maintenance engineers and more, balancing multiple weighted criteria.
MM Territories Pro helps businesses to plan and carry out door-drop deliveries as efficiently as possible, while factoring in their key criteria and restrictions.
Optimised routes that incorporate both sides of the road and minimises the number of times a route travels a particular road segment - ideal for newspaper delivery, bin collection etc.


EOD Contracts are now offering its clients Utility Service Detection/Utility Mapping along with its first class UXO services.
This service has come from a demand from our clients to provide assurance to ground teams during ground investigations. All our Engineers are fully trained (ProQual Level 3 Certificate in Utility Mapping and Detection) in use of their equipment (Leica DS2000, Leica Ultra, DGPS) and able to undertake surveys all over the UK, this can then be followed up with UXO clearance enabling the client to reduce their costs with additional manpower and mobilisation costs.


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text:
Q: Select rows in R editing to provide further clarification on the requirement
I'm fairly new in R and I've currently encountered a road block when I was tidying up my data.
My current data looks like this.
    Data
1   AAA TEXT Here
2   ZX
3   YX
4   ****
5   BBB Text Here
6   AL
7   TP
8   XY
9   ******
10 CCC Text Here
11 PP
12 QV
13 ******

AAA, BBB, CCC are like my 'identifiers' and the *** means the end of the related lines to the identifiers. In this sample output, I would only want to extract BBB and the next 3 lines after it. I would need to select in-between rows and transform my table to just this:
    Data
1   BBB Text Here
2   AL
3   TP
4   XY

Can you please help? Thanks!

A: Hmm. Your method of data storage is not what any of us would recommend, but if what you have written is indeed how you have stored your data then you can use a method outlined in this answer to find the row number of the line matching your specified identifier.
# Set up test 'identifier' value
WantedIdentifier = "BBB Text Here"

# Get matching  row number
RowNo =
  which(Text == WantedIdentifier, arr.ind=TRUE)[1]

# Return from that row to the third beyond
ReturnedText =
  if(!is.na(RowNo)) data.frame(Data = Text[RowNo:(RowNo+3),]) else NA

# Value returned
> ReturnedText
           Data
1 BBB Text Here
2            AL
3            TP
4            XY

Test data setup
Text=
  read.table(text = "Data
  'AAA TEXT Here'
  'ZX'
  'YX'
  '****'
  'BBB Text Here'
  'AL'
  'TP'
  'XY'
  '******'
  'CCC Text Here'
  'PP'
  'QV'
  '******'", header = TRUE, stringsAsFactors = FALSE)

redpajama_set_name: RedPajamaStackExchange


After 15 years of design and construction, the first proton-proton collisions were produced in the Large Hadron Collider (LHC) today. Collision observations were made in all four detectors located around the accelerator ring, including the CMS detector. The image attached to this article shows the flows of particles produced by one of the first collisions, as measured by CMS.
The University of Minnesota group is one of the leading groups on the CMS detector, with crucial development and leadership roles in the detectors designed to measure the energies of electrons, photons, and hadrons. Professor Roger Rusack, the project manager for the electomagnetic calorimeter, is present at CERN for the first collisions along with a number of graduate students and postdoctoral researchers. Professors Jeremiah Mans and Yuichi Kubota have been following the action from Minnesota. The atmosphere in the group office has been one of great excitement, with impromptu discussions of beam physics and the expected results of the first collisions breaking out among the graduate and undergraduate students as well as the professors.
The leader of the CMS collaboration, a joint effort of more than 2000 physicists and engineers, was overjoyed. "The events so far mark the start of the second half of this incredible voyage of discovery of the secrets of nature," said CMS spokesperson Tejinder Virdee.
The LHC was built to reproduce the conditions just after the Big Bang and to understand the nature of mass and perhaps produce dark matter. The first collisions have been achieved with beam energies of 450 GeV, a small fraction of the 7000 GeV design goal for the collider. Next on the schedule is an intense commissioning phase aimed at increasing the beam intensity and accelerating the beams. If all continues well, by Christmas the LHC should reach 1200 GeV (1.2 TeV) per beam, and have provided good quantities of collision data for the experiments' calibrations and initial physics studies. Further updates will surely follow soon.


text:
package org.apache.cassandra.transport.messages;

import java.nio.ByteBuffer;

import org.jboss.netty.buffer.ChannelBuffer;
import org.jboss.netty.buffer.ChannelBuffers;
import org.slf4j.Logger;
import org.slf4j.LoggerFactory;

import org.apache.cassandra.db.ConsistencyLevel;
import org.apache.cassandra.db.WriteType;
import org.apache.cassandra.exceptions.*;
import org.apache.cassandra.transport.CBUtil;
import org.apache.cassandra.transport.Message;
import org.apache.cassandra.transport.ProtocolException;
import org.apache.cassandra.transport.ServerError;
import org.apache.cassandra.utils.ByteBufferUtil;
import org.apache.cassandra.utils.MD5Digest;

/**
 * Message to indicate an error to the client.
 */
public class ErrorMessage extends Message.Response
{
    private static final Logger logger = LoggerFactory.getLogger(ErrorMessage.class);

    public static final Message.Codec<ErrorMessage> codec = new Message.Codec<ErrorMessage>()
    {
        public ErrorMessage decode(ChannelBuffer body, int version)
        {
            ExceptionCode code = ExceptionCode.fromValue(body.readInt());
            String msg = CBUtil.readString(body);

            TransportException te = null;
            switch (code)
            {
                case SERVER_ERROR:
                    te = new ServerError(msg);
                    break;
                case PROTOCOL_ERROR:
                    te = new ProtocolException(msg);
                    break;
                case BAD_CREDENTIALS:
                    te = new AuthenticationException(msg);
                    break;
                case UNAVAILABLE:
                    {
                        ConsistencyLevel cl = CBUtil.readConsistencyLevel(body);
                        int required = body.readInt();
                        int alive = body.readInt();
                        te = new UnavailableException(cl, required, alive);
                    }
                    break;
                case OVERLOADED:
                    te = new OverloadedException(msg);
                    break;
                case IS_BOOTSTRAPPING:
                    te = new IsBootstrappingException();
                    break;
                case TRUNCATE_ERROR:
                    te = new TruncateException(msg);
                    break;
                case WRITE_TIMEOUT:
                case READ_TIMEOUT:
                    ConsistencyLevel cl = CBUtil.readConsistencyLevel(body);
                    int received = body.readInt();
                    int blockFor = body.readInt();
                    if (code == ExceptionCode.WRITE_TIMEOUT)
                    {
                        WriteType writeType = Enum.valueOf(WriteType.class, CBUtil.readString(body));
                        te = new WriteTimeoutException(writeType, cl, received, blockFor);
                    }
                    else
                    {
                        byte dataPresent = body.readByte();
                        te = new ReadTimeoutException(cl, received, blockFor, dataPresent != 0);
                    }
                    break;
                case UNPREPARED:
                    {
                        MD5Digest id = MD5Digest.wrap(CBUtil.readBytes(body));
                        te = new PreparedQueryNotFoundException(id);
                    }
                    break;
                case SYNTAX_ERROR:
                    te = new SyntaxException(msg);
                    break;
                case UNAUTHORIZED:
                    te = new UnauthorizedException(msg);
                    break;
                case INVALID:
                    te = new InvalidRequestException(msg);
                    break;
                case CONFIG_ERROR:
                    te = new ConfigurationException(msg);
                    break;
                case ALREADY_EXISTS:
                    String ksName = CBUtil.readString(body);
                    String cfName = CBUtil.readString(body);
                    if (cfName.isEmpty())
                        te = new AlreadyExistsException(ksName);
                    else
                        te = new AlreadyExistsException(ksName, cfName);
                    break;
            }
            return new ErrorMessage(te);
        }

        public ChannelBuffer encode(ErrorMessage msg, int version)
        {
            ChannelBuffer ccb = CBUtil.intToCB(msg.error.code().value);
            ChannelBuffer mcb = CBUtil.stringToCB(msg.error.getMessage());

            ChannelBuffer acb = ChannelBuffers.EMPTY_BUFFER;
            switch (msg.error.code())
            {
                case UNAVAILABLE:
                    UnavailableException ue = (UnavailableException)msg.error;
                    ChannelBuffer ueCl = CBUtil.consistencyLevelToCB(ue.consistency);
                    acb = ChannelBuffers.buffer(ueCl.readableBytes() + 8);
                    acb.writeBytes(ueCl);
                    acb.writeInt(ue.required);
                    acb.writeInt(ue.alive);
                    break;
                case WRITE_TIMEOUT:
                case READ_TIMEOUT:
                    RequestTimeoutException rte = (RequestTimeoutException)msg.error;
                    boolean isWrite = msg.error.code() == ExceptionCode.WRITE_TIMEOUT;

                    ChannelBuffer rteCl = CBUtil.consistencyLevelToCB(rte.consistency);
                    ByteBuffer writeType = isWrite
                                         ? ByteBufferUtil.bytes(((WriteTimeoutException)rte).writeType.toString())
                                         : null;

                    int extraSize = isWrite  ? 2 + writeType.remaining() : 1;
                    acb = ChannelBuffers.buffer(rteCl.readableBytes() + 8 + extraSize);

                    acb.writeBytes(rteCl);
                    acb.writeInt(rte.received);
                    acb.writeInt(rte.blockFor);
                    if (isWrite)
                    {
                        acb.writeShort((short)writeType.remaining());
                        acb.writeBytes(writeType);
                    }
                    else
                    {
                        acb.writeByte((byte)(((ReadTimeoutException)rte).dataPresent ? 1 : 0));
                    }
                    break;
                case UNPREPARED:
                    PreparedQueryNotFoundException pqnfe = (PreparedQueryNotFoundException)msg.error;
                    acb = CBUtil.bytesToCB(pqnfe.id.bytes);
                    break;
                case ALREADY_EXISTS:
                    AlreadyExistsException aee = (AlreadyExistsException)msg.error;
                    acb = ChannelBuffers.wrappedBuffer(CBUtil.stringToCB(aee.ksName),
                                                       CBUtil.stringToCB(aee.cfName));
                    break;
            }
            return ChannelBuffers.wrappedBuffer(ccb, mcb, acb);
        }
    };

    // We need to figure error codes out (#3979)
    public final TransportException error;

    private ErrorMessage(TransportException error)
    {
        super(Message.Type.ERROR);
        this.error = error;
    }

    private ErrorMessage(TransportException error, int streamId)
    {
        this(error);
        setStreamId(streamId);
    }

    public static ErrorMessage fromException(Throwable e)
    {
        int streamId = 0;
        if (e instanceof WrappedException)
        {
            streamId = ((WrappedException)e).streamId;
            e = e.getCause();
        }

        if (e instanceof TransportException)
            return new ErrorMessage((TransportException)e, streamId);

        // Unexpected exception
        logger.error("Unexpected exception during request", e);
        return new ErrorMessage(new ServerError(e), streamId);
    }

    public ChannelBuffer encode()
    {
        return codec.encode(this, getVersion());
    }

    @Override
    public String toString()
    {
        return "ERROR " + error.code() + ": " + error.getMessage();
    }

    public static RuntimeException wrap(Throwable t, int streamId)
    {
        return new WrappedException(t, streamId);
    }

    private static class WrappedException extends RuntimeException
    {
        private final int streamId;

        public WrappedException(Throwable cause, int streamId)
        {
            super(cause);
            this.streamId = streamId;
        }
    }

}

redpajama_set_name: RedPajamaGithub


text:
UK police unveil largest ever counter-fraud operation
Mark Rowley
Spam Calls
Counter-fraud
Four dead and over 40 injured in London attack
Britain to toughen terrorism rules after London attack
The UK's far right bears responsibility for the bullying of the Syrian boy
Ecuador's electoral council confirms Moreno's win
Bolivia court declares Morales winner in disputed vote
Eighteen-month global probe into the iSpoof.cc website — part of a criminal network that duped victims in millions of spam phone calls — leads to 100 arrests.
"This is about starting from the organised criminals that drive and create the fraud that we see in the world around us," says Met Commissioner Mark Rowely. (Reuters Archive)
UK police have said their biggest-ever counter-fraud operation had disrupted an international criminal network targeting hundreds of thousands of victims in millions of spam phone calls.
The Metropolitan Police, which spearheaded the 18-month global probe into the iSpoof.cc website has arrested over 100 people in recent weeks, including one of its alleged London-based administrators.
Working with Europol, the FBI and other law enforcement worldwide, suspects were nabbed in the Netherlands, Australia, France and Ireland, while servers were shuttered in the Netherlands and Ukraine.
UK police believe organised crime groups are linked to the website and its tens of thousands of users, who could access software tools to help illicitly obtain victims' bank account funds and commit other fraud.
Met Commissioner Mark Rowley said the investigation signalled "a different approach" to criminals exploiting technology.
"This is about starting from the organised criminals that drive and create the fraud that we see in the world around us," he told reporters.
Millions of frauds, millions in losses
The London force — the UK's largest — said in the year to August, suspects paid to access the website and make more than 10 million fraudulent calls worldwide.
Around 40 percent were in the United States, while more than a third were in the UK, targeting 200,000 potential victims there alone.
Fraud detection agencies have so far recorded $58 million in losses in the UK alone, with the largest single theft of $3.6 million and an average of $12,000.
"Because fraud is vastly under-reported, the full amount is believed to be much higher," the Met said.
Those behind the site earned almost $3.87 million from it, the force added.
Only around 5,000 British victims have so far been identified.
However, the Met's investigation has yielded the phone numbers of more than 70,000 potential victims who have yet to be contacted.
The force will attempt to reach them over the next two days, sending text messages directing those contacted to its website, where details can be safely logged.
"What we're doing here is trying to industrialise our response to the organised criminals' industrialisation of the problem," Rowley added.
'Operation Elaborate'
The iSpoof website — described as "an international one stop spoofing shop" — was created in December 2020 and, at its peak, had 59,000 users paying between $181 and $6,041 for its services, according to the Met.
It enabled subscribers, who could pay in Bitcoin, to access so-called spoofing tools which made their phone numbers appear as if they were calling from banks, tax offices and other official bodies.
Some of the UK's biggest consumer banks — including Barclays, HSBC, Santander, Lloyds, and Halifax — were the most commonly imitated.
Combined with customers' bank and login details illegally obtained elsewhere online, the criminals were then able to defraud their victims.
"They would worry them (about) fraudulent activity on their bank accounts and tricked them," explained Detective Superintendent Helen Rance, who leads on cybercrime for the Met.
She noted that people contacted would typically be instructed to share six-digit banking passcodes allowing their accounts to be emptied.
The Met launched "Operation Elaborate" in June 2021, partnering with Dutch police who had already started their probe after an iSpoof server was based there.
The previous day the Met had charged Teejai Fletcher, 34, of east London, with fraud and organised crime group offences.
He remains in custody and will next appear in a London court on December 6.
"Instead of just taking down the website and arresting the administrator, we have gone after the users of iSpoof," she added.
Two other suspected administrators outside the UK remain at large, the Met noted.

redpajama_set_name: RedPajamaCommonCrawl


text:
Interpretation Plans
Exhibition Designs
Back to Interpretation design
Greater Manchester Fire Service Museum
CM provided the Interpretation, Exhibition and Activity Plans for Greater Manchester Fire Service Museums' round 2 application to the National Lottery Heritage Fund.
King Abdulaziz Centre of World Culture
The KACWC is a $450 Million project which includes 3 major exhibition / gallery spaces, library, conference centre, restaurants and commercial / retail development.
Rye Harbour Nature Reserve, Discovery Centre
The Rye Harbour Nature Reserve is a rare coastal landscape of outstanding geological, biological, cultural and heritage value. The project will greatly improve visitor facilities and experience.
St George's Hall, Bradford
St George's Concert Hall in Bradford is the oldest purpose-built concert hall in Britain and the third oldest in Europe. The project will restore and improve the existing theatre, and is funded by both the National Lottery Heritage Fund and the City of Bradford Metropolitan District Council.


text:
Pogonomyrmex imberbiculus is a species of ant in the family Formicidae.

References

Further reading

External links

imberbiculus
Articles created by Qbugbot
Insects described in 1902

redpajama_set_name: RedPajamaWikipedia


PDCD4 is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. De plus, nous expédions PDCD4 Anticorps (259) et PDCD4 Kits (19) et beaucoup plus de produits pour cette protéine.
These results suggested a correlation between miR421 and PDCD4, and physiological functions of breast cancer cells.
PDCD4-AS1 lncRNA positively regulates the expression and activity of the tumor suppressor PDCD4 in mammary epithelial cells. Both PDCD4-AS1 and PDCD4 show reduced expression in triple negative breast cancer cell lines and in patients, and depletion of PDCD4-AS1 compromised the cellular levels and activity of PDCD4.
miR-21 and PDCD4 might be potential biomarkers of tumor progression and indicators of prognosis of stag II esophageal carcinoma.
Low PDCD4 expression is associated with Drug Resistance in Pancreatic Cancer.
Study established that upregulation of miR-96 in glioblastoma multiforme (GBM) cells confers radioresistance via targeting PDCD4, which might be a potential therapeutic target for GBM.
This study revealed a dynamic regulatory relationship between PDCD4 and critical factors for EMT, establishing a broad, functional role for PDCD4 in laryngeal carcinoma, which may be propagated by the STAT3-miR-21 pathway.
the localization of Pdcd4 to the cytoplasm may be responsible for the suppression of the target mRNA translation and apoptosis.
PDCD4 and PTEN were the functional targets of miR-21.
In the high malignant group the PDCD4 mRNA and PDCD5 mRNA expressions were significantly decreased compared with the low malignant group and the control group. PDCD4 mRNA and PDCD5 mRNA expressions are promising targets for the diagnosis and treatment of glioma.
miR-21 may promote salivary adenoid cystic carcinoma progression via PDCD4 and PTEN down-regulation and Bcl-2 up-regulation.
The expression of PDCD4 is decreased in cervical cancer tissues, compared to miR-150 which is increased.
Our study demonstrated that lncRNA-XIST, which acts as a miRNA sponge, impedes miR-21-5p to maintain the expression of PDCD4, which contributes to the progression of osteosarcoma (OS). Our findings suggest that the newly identified XIST/miR-21-5p/PDCD4 axis could be a potential biomarker or therapeutic target for OS.
miR206 promoted the onset of SANFH by inducing apoptosis and suppressed the proliferation of osteoblasts, which was dependent on the inhibition of PDCD4.
Results found PDCD4 as a target gene of miR-93 and miR-93 could down-regulate the expression of PDCD4 by directly targeting its 3'-UTR. The re-expression of PDCD4 could attenuate the hepatocellular carcinoma (HCC) cell invasion and migration induced by miR-93, while the knockdown of PDCD4 would promote HCC cell migration and invasion via the EMT pathway.
Reduced expression of PDCD4 was found in decidual and chorionic tissues, and peripheral blood mononuclear cells from patients with missed abortion.
miR503 promotes tumour growth and invasion by directly targeting PDCD4.
A novel mechanism of Pdcd4 action as a translation inhibitor and tumor suppressor has been proposed.
Taken together, this study highlights an important role for miR-23a/b as oncomiRs in gastric cancer through the inhibition of PDCD4 translation. These findings may shed new light on the molecular mechanism of gastric carcinogenesis and provide a new avenue for gastric cancer treatment.
lncRNA CASC9 functions as an oncogene by negatively regulating PDCD4 expression through recruiting EZH2 and subsequently altering H3K27me3 level. Our study implicates lncRNA CASC9 as a valuable biomarker for ESCC diagnosis and prognosis.
These skeletal effects were attributed to inhibition of bone resorption and osteoclast function by miR-21 deficiency through miR-21 targeting programmed cell death 4 (PDCD4), despite the existence of RANKL. As far as we know, this is the first in vivo evidence of a pro-osteoclastic microRNA.
MEG3 functions as a competing endogenous RNAs (ceRNAs) and competes with PDCD4 mRNA for directly binding to miR-21, which mediates ischemic neuronal death.
-induced expression of PDCD4 is associated with increased beta cell death.
our data suggest that Pdcd4 as a crucial regulator in SGs induced by ox-LDL or HFD maybe a potential target for mitigating SG-associated stress responses in obesity and related diseases.
Pdcd4 deficiency attenuates atherosclerosis in hyperlipidemic mice in part through the upregulation of the anti-inflammatory cytokine IL-10.
PDCD4 Deficiency Aggravated Colitis and Colitis-associated Colorectal Cancer Via Promoting IL-6/STAT3 Pathway.
Study found that miR-16 was the direct regulatory element of PDCD4 and played a vital role in atherosclerosis by regulating PDCD4 and the downstream NF-kappaB and MAPK pathways.
Pdcd4 produces unfavorable influences on adipose-derived stem cells(ADSC) stemness, which contribute to adipose dysfunction, obesity and metabolic syndromes, thereby proposing Pdcd4 as a potential intervening target for regulating ADSC cells function.
PDCD4 serves as an important regulator of keratinocytes proliferation and contact inhibition in vitro.
In conclusion, miR-21 is sensitive to high-concentration glucose treatment in macrophages, and appears to have a protective effect in macrophage apoptosis induced by high concentrations of glucose via PDCD4.
we demonstrate that miR-21 regulates T-cell acute lymphoblastic leukemia cell survival via repression of the tumor suppressor Pdcd4.
these findings support the existence of a microRNA-21-responsive PDCD4/caspase-3 pathway in the pulmonary tissues that when active serves to promote endothelial apoptosis in vitro and pulmonary hypertension in vivo.
during bacterial pneumonia IFNlambda promotes inflammation by inhibiting miR-21 regulation of PDCD4.
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.


Posterior Tibial Tendonitis is a strain of the Posterior Tibial Tendon which runs along the inside of the ankle and the foot.
When there is Posterior Tibial Tendon dysfunction the tendon does not hold up the arch resulting in flat feet. This can lead to heel pain, arch pain, Plantar Fascitis and/or Heel Spurs.
With Posterior Tibial Tendonitis pain will be more severe upon weight bearing especially while walking or running.
Posterior Tibial Tendonitis occurs when the muscle is over used and the tendon (soft tissue) that connects the muscle to your bone is strained. Years of over-pronation (flat feet) can also lead to Posterior Tibial Tendon dysfunction. If you keep over using the muscle, damage to the tendon builds up and Tendonitis develops. At first the pain or swelling may come and go quickly but eventually the problem may become more permanent, eventually leading to foot collapse. A serious complication of this condition in that if left untreated the tendon may rupture leading to disability.
Early treatment of this condition is indicated to prevent serious problems. This includes the use of orthoses to support the foot and relieve tension on the tendon allowing the body to heal the area. In severe cases options include the use of plaster of Paris casts or orthopaedic walkers to immobilise the foot and ankle. In the case of tendon rupture surgical intervention is inevitable and post surgery most will require foot orthoses.


text:
Inicio › New series of micrometers RMO-G
New series of micrometers RMO-G
Amperis in its continuous commitment to innovation, presents a new line of micrometers, the RMO-G series, which uses the most advanced switching technique to generate a curly-free continuous current, with automatically regulated test ramps. This micrometer eliminates the magnetic transients by increasing the current before measuring and decreasing it after the measurement. The equipment, thanks to a very efficient filtration, has a great capacity to cancel the electrostatic and electromagnetic interference in electric fields of HV. The whole is thermally protected and against overcurrents.
Amperis presents the RMO-G series that has 7 powerful and very light micro ohmmeter models:
RMO100G - test current from 5 to 100 A, weighs only 8 kg
RMO600G - test current from 5 to 600 A, weighs only 11 kg
RMO800G - test current from 5 to 800 A, weighs only 11.5 kg
These micrometers have a high measuring range ranging from 0.1 μΩ to 999.9 mΩ. Other notable features are its resolution, which is 0.1 μΩ and its typical accuracy is ± 0.1% rdg + 0.1% FS. Optionally, a remote control unit can be purchased and the equipment can be configured so that both sides are grounded.
The equipment of the RMO-G series stores up to 500 measurements marked with date and time that can be implemented in the PC through a USB or RS232 cable. Thanks to the software we provide with the team, the results are organized in a spreadsheet to be shown in a diagram and printed on a report.
The Amperis equipment consists of 4 separate test modes: SINGLE Mode, CONTIN Mode, BSG Mode (Both sides connected to ground) and DTRtest Mode (Resistance to Dead Tank).
Regarding the DV-Win software, it offers multiple advanced functions allowing the user to record the results of the test at specific time intervals. Once the measurements have been taken, the results can be saved in various formats, printed or downloaded. The software provided by Amperis offers the acquisition and analysis of test results as well as the control of all RMO-G functions from a computer. The software stands out for allowing total control of the test device, test reports in various formats, different filters to download the results to the PC and test plans.
Next, we will define the tests that can be performed through these teams:
Single test: The equipment generates a free-flowing undulated current filtering and automatically regulated, eliminating transients
Continuous tests: The equipment generates a continuous current in permanently established durations. Depending on the test current, certain work cycles can be applied to avoid overheating.
BSG test: It has circuit breakers to ground on both sides, which provides greater security for the staff. The configuration of the test is very simple and the calculations are automatic by the internal algorithm of the device.
DTR test: specially designed to measure the resistance of the dead tank circuit in circuit breakers (since these can introduce errors in the measurement of contact resistance due to magnetization).
Among the typical applications where we can measure the resistance of non-inductive test objects, we can highlight the switches in high, medium and low voltage circuits, disconnection of high, medium and low voltage switches, busbar joints of high current, cable splices, welding joints, fuses, etc.
Connecting the test object to RMO-G: The connection diagram of the RMO-G devices corresponds to the Kelvin measurement principle (four points), connecting the voltage sensors (measurement cables of the sockets) as close as possible to the object to measure, so that a resistance in both cables will be almost zero.
We can emphasize that it is a team:
Lightweight: from 8 to 11.5 kg
Powerful: up to 800 A DC
With a wide measuring range 0 - 999.9 mΩ
Resolution 0.1 μΩ
Typical accuracy ± (0.1% rdg + 0.1% FS)
Remote control unit (optional)
Unit of both sides with ground connection (optional)
SINGLE / CONTIN / BSG / DTRtest modes
We can highlight the following main benefits and characteristics of RMO-G:
In the first place, the very high output power allows, on the one hand, a wide range of resistance measurement even using very high intensities and on the other hand the use of thinner and longer test cables, being able to adjust to the requirements of the client.
Highlights the filtered output current with a fluctuation of less than 1%
Also noteworthy is the high accuracy of the instrument ± (0.1% rdg + 0.1% FS).
Resolution of the RMO-G is 0.1 μΩ.
Various optional functions:
Rmax function: approval / rejection criterion
Built-in thermal printer (optional)
USB or RS232 communication port
Bluetooth communication (optional)
DTRtest mode
info@amperis.com


text:
Straußberg heißen folgende geographische Objekte:

 Straußberg (Sondershausen), Ortsteil der Kreisstadt Sondershausen im Kyffhäuserkreis, Thüringen

 Straußberg (Gemeinde Mittelberg), Ort bei Mittelberg im Kleinwalsertal, Bezirk Bregenz, Vorarlberg, Österreich
 Burg Straußberg, in Straußberg, Thüringen
 Hoher Straußberg, 1933 m, Gipfel der Ammergauer Alpen

Siehe auch:
 Strausberg
 Strousberg


text:
using GeoJSON, Turf, FactCheck

points = GeoJSON.parsefile(joinpath(dirname(@__FILE__),"geojson/pts.geojson"))
quantiled = Turf.quantile(points, "elevation", [10,30,40,60,80,90,99])
@fact length(quantiled) --> 7 # what should be the expected values?

infield = "elevation"
outfield = "heightIndex"
translations = Vector[[0,20,1], [20,40,2], [40,60,3], [60,Inf,4]]
reclassed = Turf.reclass(points, infield, outfield, translations)
@fact typeof(reclassed.features[1].geometry) --> GeoJSON.Point
# what's the expected output here?


text:
Despite court action, Nigeria says MTN must pay $3.9bn fine by Dec. 31
Dec. 22 2015, 5:35 am Apr. 8 2016, 7:46 am
Nigeria will not hesitate to slap its largest telecommunications company MTN with an additional fine if it fails to pay the $3.9 billion due by Dec. 31.
The Nigerian Communications Commission (NCC) had imposed an initial $5.2 billion fine on Johannesburg, South Africa-headquartered MTN, for failing to meet a deadline to disconnect 5.1 million unregistered subscribers. The fine was later cut by 25 percent to $3.9 billion and a deadline of Dec. 31 was given for the payment. But MTN had sought relief in court with the belief that "there are valid grounds upon which to challenge the fine". The court move notwithstanding, the Nigerian government says it expects MTN to pay the fine by Dec. 31 or risk more fines.
"It is the right of MTN to approach the court but there was an infraction, which MTN admitted to have committed before it pleaded for leniency that led to the reduction of the fine from N1.4 trillion to N780 billion and the subsequent December 31, 2015 deadline to pay," a statement by Nigeria's Minister of Communications, Adebayo Shittu, said.
"If it has decided to go to court, it is still within the ambit of the law. I will not intervene, since they have gone to court, we will allow the court to decide if it is right for MTN to commit those infractions and breach the laws of the land."
However, Mr Shittu noted that "it is unwise for MTN to go to court after the Federal Government had magnanimously reduced the fine. It will surely be fined for violating the rule at the expiration of the deadline, should it fail to pay the initial fine." Mr Shittu is a lawyer.
MTN whose fortunes have suffered a dip, until recently, due to the penalty imposed by the Nigerian regulator NCC, had reportedly secured the services of about six Senior Advocates of Nigeria (SANs) for the case filed before the Federal High Court in Lagos.
MTN Nigeria's Human Resources & Corporate Services Executive, Amina Oyagbola, who stressed that the company holds the Nigerian Government, its national objectives, laws and regulations in the highest regard, said the court action was a last resort, following failure of negotiations to yield any good fruit.
"The N780 billion fine has potentially dire consequences for the company, its employees, partners, stakeholders as well as the entire Nigerian telecommunications industry," she said.
"Being a significant contributor in Nigeria, MTN has an obligation to protect the interests of its ecosystem of millions of Nigerians who are directly and indirectly affected by its business operations and continuity."
What does China really want from Zimbabwe?
Family Bank of Kenya suspends 9 workers in corruption probe


text:
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F. Zaria Chinelo is a pharmacist, artist, scientist, and entrepreneur. She possesses 6+ years experience in teaching education, and web development. Zaria holds dual degrees in Molecular Biology and General Chemistry. After being hired by Vanderbilt University, she led urban students to academic success before starting Felicity Motivational Group. She has been honored as a National Merit Scholar and by Texas Instruments for her achievements. She serves as PharmPsych's editor…Learn more:
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text:
Il nome Tiramisù fa riferimento alla funicolare (per essere precisi all'ascensore inclinato) che collega la parte sud della cittadina di Osimo, in provincia di Ancona, con il centro cittadino. L'impianto è stato realizzato dalla Leitner ed è nato nel 2004.

Caratteristiche
L'impianto è un ascensore inclinato e ricorda molto il sistema in uso a Bergamo presso la funicolare di Bergamo Alta: è infatti realizzato a due binari, in modo tale da fornire un doppio servizio. Di conseguenza le cabine sono due e ognuna si alterna nella salita o nella discesa. Le cabine si incontrano a metà del percorso. Gli interni, molto moderni e tecnologici, sono opera della Leitner, cosi come anche le rotaie e tutto quello che riguarda la meccanica.

Percorso

Il percorso non è molto lungo e si svolge in parte all'aperto e in parte in galleria. Il percorso del Tiramisù è così strutturato: si parte dalla stazione di Via Cristoforo Colombo, nei pressi di uno spiazzato e si inizia la salita, che avviene all'interno di una galleria. Poco dopo si esce all'aperto e dopo pochi metri, vediamo le due cabine incrociarsi. Ripreso il percorso, la vettura continua a salire fino alla stazione di vetta, sita in una piccola traversa pedonale di via Cinque Torri.

Interscambi
Presso la stazione di Via Cristoforo Colombo è sito un maxiparcheggio di interscambio, in modo tale da far agevolare l'accesso al centro città ai turisti. Presso sempre la stazione di valle è sita inoltre un'autostazione di autobus da/per Ancona e i comuni limitrofi.

Altri progetti

Osimo
Trasporti nelle Marche
Ascensori pubblici


Recently, after hearing Essie Button rave about this nail polish, I found myself in Boots scanning the Essie nail polishes. It had been a long time coming after not painting my nails in about 5 months (YES REALLY). This shade caught my eye and my head just screamed "HELL YEAH!" Unfortunately, during that trip I'd run out of money *sobs quietly*. So the next time I was out and about, I grabbed one of these and painted my nails straight away.
The polish is such a unique colour, really beautiful for spring time. It adds a 'pop' of colour to my very minimal and well, black outfits and the finish is lovely and shiny. I find it pretty long lasting and I definitely think it is quickly becoming a favourite of mine.


text:
Home Entertainment Salma Hayek on 'my monster' Harvey Weinstein: He said 'I will kill...
Salma Hayek on 'my monster' Harvey Weinstein: He said 'I will kill you'
(L to R) Francois Pinault, actress Salma Hayek and Harvey Weinstein attend the Vanity Fair and Gucci Party Honoring Martin Scorsese during the 63rd Annual Cannes Film Festival at the Hotel Du Cap Eden Roc on May 15, 2010 in Cannes, France. (Daniele Venturelli/WireImage for Gucci)
Salma Hayek described in an op-ed Wednesday how her refusals of Harvey Weinstein's advances turned the making of 2002 Frida Kahlo biopic "Frida" into a nightmare experience.
In the shocking essay published in the New York Times, Hayek said for years she called the disgraced producer "my monster" and revealed that Weinstein would turn up at her door "at all hours of the night, hotel after hotel, location after location."
"No to opening the door to him at all hours of the night, hotel after hotel, location after location, where he would show up unexpectedly, including one location where I was doing a movie he wasn't even involved with. No to me taking a shower with him. No to letting him watch me take a shower," Hayek wrote of refusing his advances. "No to letting him give me a massage. No to letting a naked friend of his give me a massage. No to letting him give me oral sex. No to my getting naked with another woman."
He would let me finish the film if I agreed to do a sex scene with another woman
– Salma Hayek on Harvey Weinstein
HARVEY WEINSTEIN SCANDAL: WHAT YOU NEED TO KNOW
Hayek lists the many ways she denied Weinstein saying that Weinstein then made outrageous demands on the production of "Frida," which Hayek was producing, including insisting she film a sex scene with full frontal nudity.
However, the actress revealed she reluctantly agreed to one of his demands while filming "Frida."
"He would let me finish the film if I agreed to do a sex scene with another woman. It was not because I would be naked with another woman. It was because I would be naked with her for Harvey Weinstein. But I could not tell them then," she wrote.
The Mexican-born star recalled how she became physically and emotionally distraught shooting the "senseless" sex scene.
"My mind understood that I had to do it, but my body wouldn't stop crying and convulsing. At that point, I started throwing up while a set frozen still waited to shoot. I had to take a tranquilizer, which eventually stopped the crying but made the vomiting worse. As you can imagine, this was not sexy, but it was the only way I could get through the scene," she said.
And now Harvey Weinstein's spokesperson has responded to Salma Hayek's New York Times piece. Another ill-advised PR disaster, in my humble opinion. pic.twitter.com/8uZwxdbnBv
— Kate Aurthur (@KateAurthur) December 14, 2017
In a statement to Buzzfeed News, a Weinstein spokesperson said the movie mogul "does not recall" pressuring the actress into doing the sex scene, nor was he there for filming.
"All of the sexual allegations as portrayed by Salma are not accurate and others who witnessed the events have a different account of what transpired," the spokesperson said.
Hayek claimed that Weinstein even threatened her life.
"The range of his persuasion tactics went from sweet-talking me to that one time when, in an attack of fury, he said the terrifying words, 'I will kill you, don't think I can't,'" she wrote.
The A-lister shared her reasoning for not coming out sooner against the alleged sexual predator.
"When I saw him socially, I'd smile and try to remember the good things about him, telling myself that I went to war and I won."
Hayek's motivation for sharing her heartbreaking tale is to inspire change within society.
"I hope that adding my voice to the chorus of those who are finally speaking out will shed light on why it is so difficult, and why so many of us have waited so long. Men sexually harassed because they could. Women are talking today because, in this new era, we finally can."
Hayek joins a list of more than 60 women including Angelina Jolie, Ashley Judd and Gwyneth Paltrow, accusing Weinstein of sexual misconduct. Since the scandal broke in October, Weinstein was dropped by Miramax and said he entered rehab to address his behavior.
Weinstein has vehemently denied all allegations of non-consensual sex. His rep did not immediately return Fox News' request for comment.
Fox News.com Reporter and FOX411 host Diana Falzone covers celebrity news and interviews some of today's top celebrities and newsmakers. You can follow her on Twitter @dianafalzone.
See Meghan Markle's ring
Read more: www.foxnews.com
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How Fast You Can Create Your Professional Looking Website?
Here is a problem that faced by many peoples when comes to website design and creation. According to them, website creation required a lot of sophisticated web programming languages, such as HTML, PHP, ASP.NET or some even said that we need to have a least a College Degree / Diploma in order to create a professional looking website.
Then, what is your opinion about that? Does create website really a complicated things to deal with?
Here is the deal, i can challenge all the users opinions above that we are able to create a website within few hours, without "Degree" programming skills and levels, without "Extreme" creative designing skills such as Photoshop or Coral Draw. Everything is done "under one roof" by using a software called Sitebuilder.
Yes, some of us might also suggest a simple yet easy to use HTML editors such as NVU, this software are also recommended in the sense that it is FREE, easy to use, but required some basic HTML and designing skills.
1) Designed for Differentiation — Providers and end customers can select an assortment of skins to integrate with their control panels and modify look-and-feel for private branding.
2) Advanced Design Templates and Features — Hundreds of sophisticated templates (with color variants) included in combination with advanced statistics, photo albums and a powerful WYSIWYG editor.
3) Easy-to-Use Web Interface — 5-Step point-and-click wizard that includes design and layout templates, page structure, sample text, and a powerful WYSIWYG editor for non-technical users.
4) Open Architecture — Ability to modify default templates designs, add new templates, and create page sets for more advanced users.
5) Support multilingual function, such as English, German, Japanese, Spanish, French, Chinese Simplified, Chinese Traditional and Russian.
The Sitebuilder software can available Free with all SeekDotNet.com ASP.NET hosting plan. You may contact SeekDotNet.com at http://www.seekdotnet.com/contactus.aspx to get more information about this wonderful software. Or log on to http://www.seekdotnet.com/websitebuilderhosting.aspx .


Local author Jane Rice's talk about the golden age of aviation in NH IS CANCELLED DUE TO THE SNOW.
Jane Rice has written a book about her father called Bob Fogg and New Hampshire's Golden Age of Aviation, published by Peter E. Randall Publisher in Portsmouth, NH. The Center for the Book at NH State library is featuring Rice's book in February. We have the book in our collection if you want a preview of Rice's talk on Wednesday, February 27th at 7 pm.


The Waverly Community House Archives would like to wish all of our readers a very Happy New Year– we have a lot of exciting events planned for 2018 and cannot wait to share them with all of you! Today's Community Member Feature will be dedicated to Gertrude Coursen, a very ambitious, enthusiastic woman who remains present in spirit, especially through our Archive and educational programs at the Waverly Community House.
While highly successful in her instructional duties, Gertrude Coursen's significance cannot simply be measured in that regard however; Miss Coursen was one of the first creators of what is now an entire archival collection housed at the Waverly Community House. Beginning in 1920, Coursen meticulously collected each and every newspaper article, photograph, and report regarding the Comm; she then organized them into scrapbooks arranged by date and year. These books were added to regularly until the late 1940's when Coursen left and other methods of collecting materials by her successors began. The Waverly Community House Archive would not be complete without Miss Coursen and for that we are grateful. We will close out today's post below with a memorable quote from her 1922 Annual Meeting report.
In other news, the Waverly Community House is currently accepting donations of materials in preparation for our centennial anniversary. If you have any memorabilia, photographs, news articles, or materials relating to the Comm and Waverly that you would like to donate, please contact us at: (570) 586-8191 ex. 7, or via email at greviello@waverlycomm.org. We would love to be able to feature your memories in our centennial!


text:
Q: Netlogo: Selecting an agent based on multiple conditions I have 2 agents, hub and individual.
Individuals have its own variable called value.
I want to write a method that allow hub to select the individual with the highest value and has not established a link with the hub, in order to establish a link with it.
So far I am using max-one-of, which gives me the highest value-d individual the first round but on the second round the same individual is still selected despite a link has been already established with the hub.
I would like to ask all how do I get the individual that has not been linked with the hub yet, with the highest value?
Thank you very much!

A: You need to filter your individuals using with and link-neighbor?:
breed [ hubs hub ]
breed [ individuals individual ]
individuals-own [ value ]

to setup
  clear-all
  create-hubs 1
  create-individuals 10 [
    set value random 100
    forward 5
  ]
  reset-ticks
end

to go
  ask hubs [
    let candidates individuals with [ not link-neighbor? myself ]
    if any? candidates [
      create-link-with max-one-of candidates [ value ]
    ]
  ]
  tick
end


text:
Hunter Stanke
rFIA
Detection and attribution of change in forest restoration needs in the PNW
Widespread fire suppression (early 20th century to present day) and intensive tree harvesting (19th to early 20th century) have shifted the composition and structure of many western forest landscapes beyond their historic range of variability. In dry inland forests of the PNW, novel forest conditions (e.g., abundance of high density, closed-canopy forests dominated by fire-intolerant species) have interacted with changing climate to incite rapid increases in disturbance activity. In contrast, the moister forests west of the cascade crest have been shaped by a century and a half of industrial forest management, resulting in landscape fragmentation (e.g., checkerboard patterning), simplification of forest structure (e.g., predominance of early and mid-seral plantation settings, lack of coarse wood), and loss of late-seral conditions across a broad spatial domain. While patterns of change differ strongly between dry and moist forests of the PNW, reversion of landscape composition (e.g., relative abundance of community types), structure (e.g., seral-stage distributions), and function (e.g., fire regimes, nutrient cycling) towards historically ``stable" conditions is broadly assumed to increase forest resilience to future changes in disturbance regimes and environmental drivers. As such, agencies tasked with managing public forestland in the western US have broadly adopted principles of ecological restoration and landscape-scale management, and face the immense challenge of increasing the pace and scale of forest restoration in the midst of changing disturbance regimes, climate, and societal values.
Previous studies have sought to support forest restoration efforts by quantifying structural restoration needs and determining where, how much, and what forms of treatment are required to shift the structure of present-day forest landscapes to meet historically "stable" conditions across the PNW. However, these studies have been unable to quantify the uncertainty associated with their estimates of restoration need, nor the the accuracy of their approach in characterizing current vegetation at broad spatial scales. In the context of decision-making, proper quantification of uncertainty (e.g., in the form of confidence/credible intervals) is often as important as point estimation; the range of credible estimates of forest restoration need is of no less value than our "best" estimate and should be quantified whenever possible. Further, previous studies have aimed to characterize forest restoration needs at single points in time, and thus have not provided a mechanism to detect statistically significant change in restoration needs or quantify the relative importance of disturbance and successional processes in driving such change. It is reasonable to expect that the composition and structure of forested landscapes have changed considerably over recent decades in the PNW, in light of increased wildfire activity and recent outbreaks of native insects in the region. In many cases, disturbances may contribute to forest restoration objectives directly (e.g., "restoration wildfire" in the dry domain), and as such, quantifying the patterns and underlying drivers of change in forest structural restoration need is a key challenge for ecological research.
Here, we propose a re-evaluation of forest structural restoration needs in the PNW under a design-based setting (i.e., as opposed to a model-based as used previously). Specifically, we seek to (1) generate unbiased, annual estimates of forest structural stage distributions and associated uncertainty using the FIA Database over the period 2002-2019; (2) compare design-based (i.e., FIA) and model-based (i.e, GNN) estimates of restoration need to determine the "accuracy" of model-based summaries; (3) draw on remeasured FIA plots to derive an estimator of average annual change in forest restoration need over the last two decades in the PNW.
Do design-based and model-based estimates of restoration need differ in a systematic manner?
Does the magnitude of divergence in restoration need predicted under each paradigm vary across space and/or by type of treatment needed?
What stand structural stages are primarily responsible for driving divergence in restoration need, and what does this indicate about prediction uncertainty of the model-based estimator
At what spatial scales do estimates of structural stage distributions and/or restoration needs diverge, if ever?
How have forest structural restoration needs changed over the last 20 years in the Pacific Northwest?
How have natural disturbances (i.e., fire, insect outbreaks, disease, and wind), silvicultural treatments, and succession to contributed to such change?
When, where, and to what degree have natural disturbances and succession contributed directly to forest restoration objectives, and what does this indicate about optimizing the impact of limited resources for silvicultural intervention?
Since 1999 FIA has operated an extensive nationally-consistent forest inventory designed to monitor changes in forests across all lands in the US. The program measures forest variables on a network of permanent ground plots that are systematically distributed at a rate of approximately 1 plot per 2428 hectares across the US. In Oregon and Washington, sampling has been intensified on some lands (i.e., primarly national forests), often yielding estimators with higher precision within small domains (i.e., small spatial domains and/or rare forest attributes) relative to other states. Importantly, ground plots are remeasured every 10-years in the western US, and approximately 14,000 forested plots have been remeasured in Oregon and Washington to date.
Using the FIA plot network, we derive a design-based estimator of forest structural stage distributions (and subsequently restoration need) that is directly comparable to the model-based estimator used by and DeMeo et al., 2015. First, we classify FIA plots into one of five mutually exclusive structural classes using on an algorithm first presented in Huago et al., 2015. We then apply post-stratified estimators implemented in the rFIA R package to estimate total and proportion forest land area within each structural classes along with associated measures of uncertainty (i.e., variance of the estimator). Treating reference conditions as known values, we then apply a "restoration needs" algorithm described in Huago et al., 2015 to estimate total restoration need within classified domains (e.g., HUC units, ownership types, etc). The purpose of this "restoration needs" algorithm is to shift land area from over-represented structural classes (relative to historic conditions) to under-represented classes. Importantly, these shifts do not affect the variance of the estimator of total forest land area as we are simply adding/subtracting scalars in each case. That is, the variance of the estimator of total forest restoration need is exactly equal to that of the estimator of total forest land area using this approach, as reference conditions are not treated as random variables but as fixed, known boundaries.
Similarly, we derive an estimator of average annual change in forest restoration need by redefining FIA's current area inventories to include only remeasured plots. In short, this allows us to estimate structural stage distributions at two points in time using an identical sample of FIA plots, and hence estimate temporal change in forest restoration need. Further, we can directly attribute changes in structural stage distributions to natural forest disturbances, silvicultural treatments, and succession (transition in structural class in the absence of disturbance/treatment) using disturbance codes collected by FIA field crews. Estimated change in structural stage distributions arising from such processes can then be used in our "restoration needs" algorithm to determine the degree to which natural disturbance, silvicultural treatment, and succession have contributed to restoration objectives within classified domains.
My research interests include disturbance, forest, and landscape ecology, and I am interested in the application of advanced spatio-temporal statistical methods to answer pressing questions in natural resource management and ecology.
Powered by the Academic theme for Hugo.


Honda BRIO is being developed with Honda's advanced technologies, while further advancing Honda's "man maximum, machine minimum" concept*1. Being developed as a commuter car which is easy-to-use even in urban areas, the Honda BRIO adopts an easy-to-handle compact body while ensuring sufficient cabin space achieved through highly efficient packaging. With this vehicle, Honda thoroughly pursued the creation of an advanced exterior form, which is compact while asserting a strong presence.
The BRIO is equipped with Honda's 1.2-liter 4-cylinder i-VTEC engine delivering 90 horsepower. This i-VTEC engine combines stress-free driving throughout the rpm range with outstanding fuel economy of 5 liters/100km*2. Its fuel economy-enhancing technologies and nimble performance makes the compact car enjoyable and fun to drive. Emissions from the Brio meets the stringent Euro 4 emission standards.
BRIO features Honda's safety technologies including dual SRS front airbags, disc brakes, Anti-Lock Brake System (ABS) which prevents wheel locking and Electronic Brake Distribution (EBD) which enhances braking performance. (available in all versions).
Incorporating Honda's G-Force Control (G-CON) technology, the BRIO's high-performance body features several outstanding elements that enhance its design, driving performance, ride comfort and collision safety performance. Its high performance body satisfies safety standards for both front and side impacts as specified by the UN Economic Commission for Europe (UNECE)'s regulations 94 and 95, respectively.


text:
Marcin z Krosna (ok. 1502-1561) – urodzony w Krośnie, profesor medycyny Akademii Krakowskiej.

Wykładowcy Akademii Krakowskiej
Lekarze I Rzeczypospolitej
Urodzeni w XVI wieku
Ludzie urodzeni w Krośnie
Zmarli w 1561


OBJECTIVE: To determine whether children with unilateral hearing loss (UHL) demonstrate worse language skills than their siblings with normal hearing, and whether children with UHL are more likely to receive extra assistance at school.
PATIENTS AND METHODS: We conducted a case-control study of 6- to 12-year-old children with UHL compared with sibling controls (74 pairs, n = 148). Scores on the oral portion of the Oral and Written Language Scales (OWLS) were the primary outcome measure. Multivariable analysis was used to determine whether UHL independently predicted OWLS scores after we controlled for potential confounding variables.
RESULTS: Children with UHL had worse scores than their siblings on language comprehension (91 vs 98; P = .003), oral expression (94 vs 101; P = .007), and oral composite (90 vs 99; P < .001). UHL independently predicted these OWLS scores when multivariable regression was used with moderate effect sizes of 0.3 to 0.7. Family income and maternal education were also independent predictors of oral expression and oral composite scores. No differences were found between children with right- or left-ear UHL or with varying severity of hearing loss. Children with UHL were more likely to have an individualized education plan (odds ratio: 4.4 [95% confidence interval: 2.0–9.5]) and to have received speech-language therapy (odds ratio: 2.6 [95% confidence interval: 1.3–5.4]).
CONCLUSIONS: School-aged children with UHL demonstrated worse oral language scores than did their siblings with normal hearing. These findings suggest that the common practice of withholding hearing-related accommodations from children with UHL should be reconsidered and studied, and that parents and educators should be informed about the deleterious effects of UHL on oral language skills.
Although BHL has been known to cause speech-language and academic delays, as well as lower rates of literacy and high school graduation, the effects of UHL on a child's speech-language development and academic achievement have not been well documented.
Results of our study demonstrate that elementary school-aged children with UHL have significantly worse oral language scores than do their siblings with NH. The common practice of withholding hearing-related accommodations from children with UHL should be reconsidered and studied.
Unilateral hearing loss (UHL) in children affects 0.4 to 34 per 1000 newborns and 1 to 50 per 1000 school-aged children.1,–,4 Although bilateral hearing loss (BHL) in children has been known to cause speech-language delays, delays in academic achievement, and lower rates of literacy and high school graduation, the effects of UHL on a child's speech-language development and academic achievement have not been well documented. In small studies from the 1980s and 1990s, it was suggested that compared with peers with normal hearing (NH), children with UHL experienced increased rates of grade failures (24%–35% vs 3% in the NH population), needed extra educational assistance (12%–41%), and had increased behavioral problems.5,–,8 However, these studies were often uncontrolled or poorly controlled (there were more cases than controls) or had significant selection biases (there were unclear reasons for inclusion or a lack of data on all children). Although quality of life has not been directly assessed in children with UHL, adults with UHL have expressed negative psychosocial effects of UHL, such as decreased quality of life; feelings of frustrations, embarrassment, and annoyance; and increased hearing handicap.9,10 Considerable biases may have affected the outcome of these studies, and little has been done to determine whether children with UHL were indeed at risk for problems in school, independent of potential confounding factors.11 As a result, health and education professionals have often discounted the effect of UHL on a child's speech and language acquisition or academic achievement.
Limited information exists about the effect of UHL on acquisition of speech and language skills in infants and toddlers. Kiese-Himmel12 reported that the average age of the first word spoken was 12.7 months (range: 10–33 months) and the average age of the first 2-word phrase was 23.5 months (range: 18–48 months). Although the age of the first word uttered was not delayed, the average age of the first 2-word phrase was delayed an average of 5 months on the basis of a norm of 18 months. Results were reported on 15 children with UHL in the Colorado Home Intervention Program reported who were followed since infancy.13 Their speech and language skills were assessed when the children were at least 12 months old. None had another known disability, but 4 (27%) had significant language delays, and 1 (7%) had a borderline language delay.
Other risk factors for educational delay may be extrapolated from studies of children with BHL. For young children who are deaf or hard-of-hearing, the level of parental involvement and age at enrollment into a comprehensive intervention program were most strongly associated with speech and language outcomes at age 5.17 In children with cochlear implants, reading competence was associated with higher nonverbal intelligence, higher socioeconomic status, female gender, and later onset of deafness (after birth).18 In addition, speech production and language skills predicted the greatest amount of variance in the reading outcome, which suggests that avoiding speech and language delay is associated with improved prognosis for developing literacy. Thus, variables related to the child, family, and socioeconomic status may affect speech and language development, reading competence, and thereby educational achievement.
The purpose of this study was to determine whether a large sample of elementary school-aged children with UHL demonstrated significantly worse language skills than did their sibling controls with NH. Using sibling controls minimized the confounding effects of family and environment on the development of language skills.
Institutional review board approval through the Human Research Protection Office at Washington University School of Medicine was obtained before the onset of this study. All parent and child participants signed written informed-consent and pediatric assent forms, respectively.
We conducted a case-control study of children with UHL compared with sibling controls with NH.
Children aged 6 to 12 were recruited from the pediatric otolaryngology clinics at St Louis Children's Hospital and Washington University School of Medicine and several regional school districts: St Louis City Public Schools, Special School District of St Louis County, and the Belleville Area Special Services Cooperative (Illinois). Children from the school districts were identified through hearing screening programs or audiology testing associated with the school districts and not as a result of receiving special services.
Children were excluded if they had temporary or fluctuating conductive hearing loss or had a medical diagnosis associated with cognitive impairment (eg, Down syndrome or congenital cytomegalovirus infection) or cognitive impairment per parental report.
Control subjects were eligible if they were siblings of participants with UHL, 6 to 12 years old, had NH in both ears, and did not meet any of the exclusion criteria listed above.
Subjects' demographic information, parental socioeconomic data, current and past medical history, and educational history were obtained through a parental questionnaire and interview. Subjects' percentage of the federal poverty level (FPL) was calculated by using family size and income.19 The percentage of FPL was then categorized into 3 levels: <100% of FPL; 100% to 200% FPL; and >200% FPL.
Hearing outcomes were measured in a sound-treated booth. PTAs were calculated as the average of 500, 1000, 2000, and 4000 Hz. Severity of hearing loss in the worse ear was categorized as mild if the PTA was <40-dB HL; moderate if the PTA was 40 to 69 dB HL; severe if the PTA was 70- to 89-dB HL; and profound if the PTA was ≥90-dB HL. Word-recognition scores (WRS) were obtained monaurally in quiet using Central Institute for the Deaf W-22 word lists through headphones at 40 dB above the speech-reception threshold or the participant's most comfortable loudness level. WRS in noise using Central Institute for the Deaf W-22 word lists were obtained through soundfield testing at 5- and 0-dB signal-to-noise ratios, with noise consisting of recorded 8-talker speech babble.
Secondary outcomes recorded included parents' report of speech-language delay or problems, receipt of speech-language therapy, and provision of individualized educational plans (IEPs) or Section 504c accommodations for hearing disability at school.
Descriptive statistics were obtained for each group and included means and SDs, medians and interquartile ranges, and frequency counts. With bivariate analyses, we examined speech-language score outcomes associated with patient demographic, baseline clinical, and risk factor variables. A Student's t test or 1-way analysis of variance was used for continuous variables. A χ2 or Fisher's exact test was used for categorical variables. Bivariate analysis of other outcomes involved calculating the odds ratio (OR) and 95% confidence interval (CI). A 2-tailed α level of .05 was considered statistically significant.
Multivariable linear regression was used to control for the effect of multiple independent predictors of OWLS scores. Variables with a bivariate P value of <.25 were candidates for selection into multivariable regression models to reduce type II (or β) error.22 Final multivariable models were developed to maximize the adjusted model R2 and include predictor variables with partial R2 values of ≤0.01. Models were checked for interactions and influence, and plots of residuals were examined. Statistical analysis was performed by using SAS 9.1.3 (SAS Institute, Inc, Cary, NC).
Seventy-four pairs of case-control siblings (148 subjects) were included in the analysis. Characteristics of the children with UHL and their families are shown in Table 1. The majority had profound UHL, and the greatest proportion was identified via preschool or school screening. Other ways that UHL was identified included clinical suspicion of hearing loss, such as after head trauma or meningitis. The mean age of identification of UHL was 4.7 years (SD: 2.6). Hearing loss was deemed "congenital" if it was identified through a newborn hearing screening or attributed to temporal bone abnormalities found on computed tomography or MRI. None had syndromic hearing loss. UHL had progressed in 15% of the subjects. Fewer than half of the subjects had trialed amplification and/or assistive devices, and some had tried more than 1 option. Twelve percent of families had incomes below the 2005 FPL.
Other demographic and baseline characteristics of the subjects are shown in Table 2. No demographic or cognitive differences existed between children in the case and control cohorts. Only 1 child, a control, had a full-scale IQ of <70; none had performance IQs of <70. More children with UHL suffered head trauma (OR: 4.1 [95% CI: 1.3–13.1]), received speech therapy (OR: 2.6 [95% CI: 1.3–5.4]), and had an IEP or Section 504c accommodations (OR: 4.4 [95% CI: 2.0–9.5]). No differences in neonatal risk factors for hearing loss23 were identified, including a history of jaundice or hyperbilirubinemia, NICU admission, ventilator or extracorporeal membrane oxygenation use, intravenous antibiotics, or persistent pulmonary hypertension of the newborn (data not shown). In addition, the proportions of children who had a history of recurrent otitis media and tympanostomy tubes, attention-deficit/hyperactivity disorder, and school-related behavioral problems (ie, inattention, disruptive behavior, social isolation, or another teacher-identified problem) were not significantly different.
The bivariate effect of UHL and potential confounders on the OWLS scores are shown in Table 3. Children with UHL had lower scores on all 3 OWLS scores. Race/ethnicity, gender, and income level did not have a significant effect on LC; however, all 3 affected OE scores, and race/ethnicity and income level affected OC scores significantly. No differences in the OWLS scores were found between children with right- or left-ear UHL or with severity of hearing loss. No differences in risk factors for speech or language delay24 were identified, including a child's birth order, whether he or she was born with very low birth weight, or whether the child had a history of tympanostomy tubes (data not shown).
Table 4 shows the persistent, independent negative effect of UHL on the OWLS scores after adjustment for confounding variables by using multivariable linear regression. UHL was associated with a 10.8-point decrement in LC, a 4.1-point decrement in OE, and a 5.7-point decrement in OC scores. The difference in scores translated to effect sizes of 0.3 to 0.7, or small-to-moderate effects. Severity of UHL accounted for >1% of the total variance for only LC scores. The multivariable models accounted for 34% to 61% of the total variance in scores.
In addition to UHL, the socioeconomic variables of income level and maternal education were significantly associated with OE and OC scores. Because FPL was a 3-level variable, being below the FPL was associated with a 7-point decrease in OE and an 8-point decrease in OC scores. Because maternal education was coded by yearly increments, children with mothers who are college graduates would be predicted to have OE scores of 3.2 points higher than those of children whose mothers graduated from high school only.
Multivariable models for predicting OWLS scores in children with UHL only are shown in Table 5. Although the variables in the models are largely the same, additional variables added small increments to the overall adjusted R2 values. For LC, the current use of any amplification (eg, FM system, hearing aid, or bone-anchored hearing aid [BAHA]) was associated with a small increase. For both OE and OC scores, the age at which the UHL was identified added to the overall variance explained. In addition, WRS in noise added to the overall variance explained for the OC scores. For children who had received services through an IEP, the age at which services began and duration of these services were not associated with the OWLS scores (data not shown).
In contrast with previous studies of children with UHL, we enrolled a large number of elementary school–aged children, carefully described their hearing, cognitive, and socioeconomic status, and included sibling controls. The results showed that UHL is associated with a significant negative effect on scores on standardized speech-language tests. Obtaining cases and controls within families controlled for a host of family, genetic, socioeconomic, and environmental factors that could affect language development. Although speech-language scores do not translate directly into school performance, the secondary outcomes of speech therapy and IEPs suggest that the children with UHL had significant problems in school. The multivariable-analysis results suggested that use of amplification might be associated with a small increase in LC scores. We do not think selection bias influenced these results, because the participants with UHL were identified through hearing-screening programs or diagnostic audiograms, not through special-services programs at schools.
The etiology of UHL in children may encompass a different spectrum than BHL. Genetic mutations, such as connexin 26 mutations, rarely cause UHL, and syndromic hearing loss usually involves both ears.25 The most commonly known etiologies in UHL are temporal bone anomalies, such as enlarged vestibular aqueduct, cochlear dysplasias, and cochlear nerve aplasia.26,–,28 Familial or hereditary UHL is rare and not well characterized.29,–,31 Head trauma is a relatively common etiology of acquired UHL, but the frequencies of intrauterine infections, meningitis, otologic surgery, and ototoxic medications in UHL have not been well tallied.32 Children with microtia or auricular atresia may have syndromic hearing loss (eg, Goldenhar syndrome) but usually have conductive or mixed hearing loss that is well treated with BAHA.33,–,35 Because neonatal risk factors for hearing loss have been identified in children with congenital BHL, it is not known whether the same risk factors are important for children with UHL. Research is necessary to discover which risk factors and etiologies are associated with UHL.
No study of UHL has investigated whether severity of hearing loss affects speech or language outcomes. However, studies of children and adults with asymmetric BHL have revealed that sound localization and speech discrimination are more difficult and outcomes are poorer than in children and adults with symmetric BHL.36,–,39 We speculate that when the difference in hearing between ears exceeds a threshold level, a person with UHL may experience difficulty with sound localization or speech discrimination in noise similar to that experienced by a person with asymmetric BHL. However, additional research is necessary to determine whether a threshold effect might exist.
Unlike for children with BHL, who are routinely fitted with hearing aids and receive accommodations for disability, children with UHL may not be considered to have a "significant hearing loss" because their hearing loss is not bilateral (eg, in Delaware) or not sufficient to interfere with speech or language development (eg, in Arkansas, Kentucky, or Utah).40 Each state has the right to define who is eligible for Part B and Part C of the Individuals With Disabilities Education Improvement Act (IDEA) of 2004, and UHL is often not included.41 Therefore, children with UHL are not automatically eligible for services in the First Steps or Birth to Three programs (Part C of the IDEA), preschool or school IEPs (Part B of the IDEA), or Section 504c of the Rehabilitation Act of 1973 accommodations for disability.42 Recommended interventions for children with UHL usually include preferential seating in class and an FM system that amplifies the teacher's voice relative to the background noise. Unless the child has another school-related issue (such as speech or behavior) or demonstrates significant developmental or educational delay, parents must often strongly advocate for their children with UHL to obtain FM systems in the classroom. In addition, parents may be actively discouraged by school teachers and administrators from seeking Section 504c accommodations. Only 3 children with UHL in this study had Section 504c accommodations. Independent private or parochial schools may not have the resources or the mandate to provide these accommodations. Our results suggest that children with UHL should be eligible for the same accommodations as children with BHL.
Health disparities affected this study cohort significantly. Poverty was associated with decreases in speech-language scores similar in magnitude to UHL. Compared with those in the >200% FPL bracket, the OE and OC scores for children from families at 100% to 200% of FPL were lower by 4 points, and lower by 7 to 8 points in children from families at <100% of FPL. Thus, a child with UHL who comes from a family with an income of <100% FPL would be expected to have an OE score of 11 points and an OC score 14 points below a child with NH and whose family income is at >200% FPL. These large differences in oral language skills on the basis of socioeconomic status are consistent with education and health disparities noted by others43 and have policy implications for health care and education. Although gaps in standardized achievement scores have not been measured directly in this cohort, speech and language development contribute to reading and literacy.44,–,46 Interventions that reduce the negative impact of UHL on children should address both the functional problem of hearing with only 1 ear and the problems that poverty encompasses in affecting childhood language development.
Future research to determine when the onset of speech-language delays occurs, the mechanisms whereby UHL affects speech-language development, whether any interventions can mitigate the effects of UHL, and whether speech-language delays affect future educational performance and job acquisition are all necessary to allow children the opportunity to attain their potential.
This work was supported by National Institutes of Health grants K23DC006638 and UL1RR024992. Dr Lieu had full access to the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. The sponsor had no role in the design or conduct of the study; collection, management, analysis, or interpretation of the data; or preparation, review, or approval of the manuscript.
Drs Lieu, Murray, and Piccirillo came up with the study concept and design; Drs Lieu and Karzon acquired the data; Dr Lieu analyzed and interpreted the data, drafted the manuscript, provided statistical analysis, obtained funding, and supervised the study; Drs Lieu, Karzon, Murray, and Piccirillo critically revised the manuscript; and Drs Lieu, Karzon, Murray, and Piccirillo provided administrative, technical, and material support.
This work was presented in part at a meeting of the American Auditory Society; March 7, 2009; Scottsdale, Arizona; and at a meeting of the American Society for Pediatric Otolaryngology; May 23, 2009; Seattle, Washington.


@tomax: Unfortunately, I'm not. I actually had to downsized my collection and let em go since space has become an issue. I came to a point that I bought anything that fancied my eye and anything that I find interesting. But I eventually realized that it wasn't practical and my wife told me that no matter how many toys I buy, companies won't stop making em and I would just be on the loosing end. From then on, I had to streamline my collection and just focus on the one's that I really like.
As for buying doubles or even multiple figures, I've been doing that ever since. I'm into army building too and some of my figs are being played with by my kids.
I'm way into army building as well. Most of us buy two or even multiple of the same figure.... like the Star Wars toys fake advert from Saturday Night Live...buy three, one to keep mint, one to open and one 'just because'!
I, like most here enjoy haul pics. Yours are ALWAYS noteworthy.
Last edited by ukmu; 04-06-2017 at 01:38 AM..
Too darn lazy to take a pick individually.
bumblebree, you're an artist with that camera!
I love your GI Joe pictures. Cobra Troopers and BATs are long time Joe favorites of mine.
Last edited by Ikki; 08-29-2017 at 09:29 AM..
@Ikki: Thanks. I agree with you. The Darkest Night figs are well sculpt. Love taking pics of those figures.
My goodness, you buy two each of the same figure? You must be quiet rich !
@ddarko: Wish I was rich. But I try to look for clearance or sale items. You'd be surprise that Ebay would also have good deals especially when buying in lot listings.


Today, the use of experimental animals for testing of cosmetics is prohibited. But in biomedical research, experimental animal models are often indispensable.
Ellen van den Bogaard (Dept. Dermatology/Laboratory of Medical Immunology) has now proven that in certain cases the use of experimental animals can be avoided by using tissue engineered tissue. With tissue engineered skin she revealed the ancient mystery of why coal tar is effective against eczema.
On Friday 28th of March, Ellen van den Bogaard will defend her thesis entitled: From skin development to disease pathogenesis and therapeutics - The power of 3D skin models. With 3D skin models generated from skin cells isolated from healthy volunteers or patients with eczema or psoriasis, she performed fundamental and translational research on the biology of the skin and disease pathogenesis. The most remarkable result from her studies is the discovery that the aryl hydrocarbon receptor mediates the therapeutic effect by coal tar on eczema skin. This receptor stimulates the production of skin barrier proteins thereby repairing the dysfunctional skin barrier in eczema patients.
Notably, this research was performed without using experimental animals and solely based on 3D tissue engineered skin. "Experimental animals for biomedical research will always be necessary", according to Van den Bogaard, for example if we want to know how a living organism in sickness or health responds to a substance. "But with the aid of 3D reconstructed skin we can at least refine and reduce the use of experimental animals". Besides ethical issues regarding experimental animal use, there are also scientific objections. The skin of rodents is quite different from human skin and the phenotype of knockout mice is therefore not always comparable to gene function in human skin, states Van den Bogaard in her thesis.
The research on coal tar treatment and aryl hydrocarbon receptor signaling in skin will be part of Van den Bogaard's future work as a post-doc in the Dermatology department. And where possible this work will also be performed with a minimum of experimal animals.
Ellen H.J. van den Bogaard - From skin development to disease pathogenesis and therapeutics, 'The power of 3D skin models'.
Thesis Radboudumc. Promotion date 28 March 2014. 12.30 hrs.
Promotors: prof. J. Schalkwijk, prof. I. Joosten. Copromotor: dr. P.L.J.M. Zeeuwen.


text:
Here's Why Death Stranding Is A PlayStation Exclusive
In Playstation News
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When Death Stranding was revealed as a PlayStation 4 exclusive at E3 2016, people were quick shocked that Kojima had landed an exclusivity deal and was so far along with a brand new concept so quickly.
When asked by Greg Miller at RTX Sydney about why he chose PlayStation as the exclusive home for Death Stranding, Kojima said that he chose PlayStation due to the mutual respect and because he has been working with the company for over 20 years.
He said that he wanted to make sure that the first game as an independent developer was a major success whilst still being his creative baby. He said that he knew there would be little chance to fail with PlayStation.
When asked about PlayStation's involvement in development, Kojima said that they'd never forced him into tacking things such as VR onto the game and that they were largely in control of promotion and advertising ,but he still had a massive input on this.
He spoke specifically about the trailer at E3 and the fact that that if it were any other company, they'd have been against that. The fact that Norman Reedus was naked and not much about the game was shown wouldn't have been allowed by other major publishers.
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