text:
@echo off

:: %1 - The architecture tag (x64 | x86)
:: %2 - The toolchain name (vc11 | vc12, vc14, vc141, etc)
:: %3 - The openssl version (1.1.1d, etc)
:: %4 - The build type (debug vs. release)

setlocal

set SCRIPTS_DIR_WITH_TRAILING_SLASH=%~dp0
pushd %SCRIPTS_DIR_WITH_TRAILING_SLASH%..\..

if "%CI_ENV_ROOT%" == "" (
  echo CI_ENV_ROOT must be defined
  goto error
  )

call %CI_ENV_ROOT%\scripts\ci\ci-init-env.bat
if %ERRORLEVEL% NEQ 0 goto error

if "%DIST_ROOT_DEPS1%" == "" (
  echo DIST_ROOT_DEPS1 must be defined by %CI_ENV_ROOT%\scripts\ci\ci-init-env.bat
  goto error
  )

set ARCH_NAME=%1
if "%ARCH_NAME%" == "" set ARCH_NAME=x64

set TOOLCHAIN_NAME=%2
if "%TOOLCHAIN_NAME%" == "" set TOOLCHAIN_NAME=vc141

set OPENSSL_VERSION_NAME=%3
if "%OPENSSL_VERSION_NAME%" == "" set OPENSSL_VERSION_NAME=1.1.1d

set BUILD_TYPE=%4
if "%BUILD_TYPE%" == "" set BUILD_TYPE=debug

call %SCRIPTS_DIR_WITH_TRAILING_SLASH%%TOOLCHAIN_NAME%env_%ARCH_NAME%_from_make.bat
if %ERRORLEVEL% NEQ 0 (
  echo error invoking the toolchain configuration file %SCRIPTS_DIR_WITH_TRAILING_SLASH%%TOOLCHAIN_NAME%env_%ARCH_NAME%_from_make.bat
  goto error
  )

set OPENSSL_SOURCE_PATH=%DIST_ROOT_DEPS1%\openssl\%OPENSSL_VERSION_NAME%\source-windows

if not exist %OPENSSL_SOURCE_PATH% (
    echo Path %OPENSSL_SOURCE_PATH% does not exist
    goto error
)

set OPENSSL_ROOT_PATH=%CD%\bld\swblocks\openssl\%OPENSSL_VERSION_NAME%\win7-%ARCH_NAME%-%TOOLCHAIN_NAME%-%BUILD_TYPE%

if exist %OPENSSL_ROOT_PATH% (
    echo Deleting existing openssl build in %OPENSSL_ROOT_PATH% ...
    rm -rf %OPENSSL_ROOT_PATH%
    if %ERRORLEVEL% NEQ 0 (
        echo error deleting existing openssl build in %OPENSSL_ROOT_PATH% ...
        goto error
        )
)

mkdir %OPENSSL_ROOT_PATH%
if %ERRORLEVEL% NEQ 0 goto error

pushd %OPENSSL_ROOT_PATH%
if %ERRORLEVEL% NEQ 0 goto error

echo Copying files from %OPENSSL_SOURCE_PATH% to %OPENSSL_ROOT_PATH% ...
robocopy /E %OPENSSL_SOURCE_PATH% . > ..\log_src_filecopy.log 2>&1
if %ERRORLEVEL% GTR 1 (
  echo error while copying files, see %OPENSSL_ROOT_PATH%\log_src_filecopy.log
  goto error
  )
move ..\log_src_filecopy.log .

echo Bootstrapping the makefile (log file is %OPENSSL_ROOT_PATH%\log_bootstrap.log) ...

set Path=%DIST_ROOT_DEPS1%\strawberry-perl\latest\default\perl\bin;%Path%

if "%ARCH_NAME%" == "x64" (
  set BUILD_CONFIG_NAME=VC-WIN64A
  ) else (
  set BUILD_CONFIG_NAME=VC-WIN32
  )

if "%BUILD_TYPE%" == "debug" (
  perl Configure %BUILD_CONFIG_NAME% no-asm no-shared --debug --prefix=%OPENSSL_ROOT_PATH%\out --openssldir=%OPENSSL_ROOT_PATH%\out\ssl -Od -Ob0 -Oy- -EHs -Zi -GS -bigobj > log_bootstrap.log 2>&1
  :: do some replacements to turn off the bad CRT debugging stuff
  bash -c "sed -ie 's/\/MDd/\/MD/g' ./makefile"
  bash -c "sed -ie 's/\-DDEBUG//g' ./makefile"
  bash -c "sed -ie 's/\-D_DEBUG//g' ./makefile"
  ) else (
  perl Configure %BUILD_CONFIG_NAME% no-asm no-shared --release --prefix=%OPENSSL_ROOT_PATH%\out --openssldir=%OPENSSL_ROOT_PATH%\out\ssl -O2 -Ob1 -Ot -Oi -Oy- -EHs -Zi -GS -bigobj -Zo -DNDEBUG > log_bootstrap.log 2>&1
  )
if %ERRORLEVEL% NEQ 0 goto error

echo Building openssl (log file is %OPENSSL_ROOT_PATH%\log_openssl_build.log) ...
nmake > log_openssl_build.log 2>&1
if %ERRORLEVEL% NEQ 0 (
    echo Building openssl failed, see log file here: %OPENSSL_ROOT_PATH%\log_openssl_build.log
    goto error
    )

echo Testing openssl (log file is %OPENSSL_ROOT_PATH%\log_openssl_test.log) ...
(nmake test) > log_openssl_test.log 2>&1
if %ERRORLEVEL% NEQ 0 (
    echo Testing openssl failed, see log file here: %OPENSSL_ROOT_PATH%\log_openssl_test.log
    :: TODO: release tests are failing die to some issue that seems benign
    :: TODO: more details here: https://github.com/openssl/openssl/issues/8694
    if "%BUILD_TYPE%" NEQ "release" (
        goto error
        )
    )

echo Installing openssl (log file is %OPENSSL_ROOT_PATH%\log_openssl_install.log) ...
(nmake install) > log_openssl_install.log 2>&1
if %ERRORLEVEL% NEQ 0 (
    echo Installing openssl failed, see log file here: %OPENSSL_ROOT_PATH%\log_openssl_install.log
    goto error
    )

set OPENSSL_TARGET_PATH=%DIST_ROOT_DEPS1%\openssl\%OPENSSL_VERSION_NAME%\win7-%ARCH_NAME%-%TOOLCHAIN_NAME%-%BUILD_TYPE%

if exist %OPENSSL_TARGET_PATH% (
    echo Deleting existing openssl build in %OPENSSL_TARGET_PATH% ...
    rm -rf %OPENSSL_TARGET_PATH%
    if %ERRORLEVEL% NEQ 0 (
        echo error deleting existing openssl build in %OPENSSL_TARGET_PATH% ...
        goto error
        )
)

mkdir %OPENSSL_TARGET_PATH%
if %ERRORLEVEL% NEQ 0 goto error

robocopy /E %OPENSSL_ROOT_PATH%\out %OPENSSL_TARGET_PATH% > ..\log_dst_filecopy.log 2>&1
if %ERRORLEVEL% GTR 1 (
  echo error while copying files to %OPENSSL_TARGET_PATH%, see %OPENSSL_ROOT_PATH%\log_dst_filecopy.log
  goto error
  )
move ..\log_dst_filecopy.log .

move log_* %OPENSSL_TARGET_PATH%
if %ERRORLEVEL% NEQ 0 (
  echo error while moving the log files to %OPENSSL_TARGET_PATH%
  goto error
  )

move makefile %OPENSSL_TARGET_PATH%
if %ERRORLEVEL% NEQ 0 (
  echo error while moving the makefile to %OPENSSL_TARGET_PATH%
  goto error
  )

popd
rm -rf %OPENSSL_ROOT_PATH%
if %ERRORLEVEL% NEQ 0 (
  echo error while deleting the root directory %OPENSSL_ROOT_PATH%
  goto error
  )

:okay
echo Done, openssl was built successfully!
popd
endlocal
exit /b 0

:error
popd
endlocal
exit /b 1


These certificate programs help you achieve your goals: whether they are to develop new skills, keep abreast of current best practices, or develop your knowledge. You will also improve your ability to stay focused on long-term issues while addressing short-term conditions. UC Davis Extension's courses are highly regarded by local employers for their real-world focus, immediate applicability, and up-to-date information.
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Bristol is a city of rich history, but which of the claims made about the city are actually true?
We've already sorted out slaves in the caves, the crocodile, Ribena, Easter eggs and chocolate bars, and now we've got a new set of claims made about Bristol to run the comb of truth over.
These are the things people say, hear, read or pass down the generations, without always being sure whether they are true: Did someone really survive jumping from the Clifton Suspension Bridge? Is that lane really named after a children's TV presenter?
So buckle up, because this is going to be a bumpy ride, with a few big drops and a lean to the side.
Truth factor 9/10: We did indeed!
Nipper was his name, and he was born in Bristol. The image of the mixed-breed dog intently listening to an old fashioned gramophone, with his head cocked to one side, became iconic and is still well known and well used around the world by everyone from RCA and EMI to, obviously, HMV, the record store named after that image: His Master's Voice.
It doesn't quite get a full ten out of ten though, and this may seem a bit harsh, for the simple reason that he was only a Bristol dog for a few short years. Born in 1884, his owner Mark Barraud was the scenery designer at the Prince's Theatre. But Mark died in 1887, when Nipper was just three, and the dog moved to live with Mark's brothers, Philip and Francis.
He died, still in canine and music history obscurity, in 1895, at the age of 11, and was buried in Kingston in Surrey.
It wasn't until three years later that Francis painted a picture from memory of Nipper listening to a gramophone, and hawked it around the early gramophone companies, thinking to use it as an advertising image – showing that their new machines had such crystal clear sound that even a dog would recognise his own master's voice. One bought it, and the rest is history.
However, the slim Bristol connection was enough for Nipper to be remembered in the city, not only with a blue plaque but a statue, which can be seen on the building at the corner of Park Row and Woodland Road, looking towards the place where the Prince's Theatre stood before it was destroyed in the Bristol Blitz, in November 1940.
Truth factor 10/10: It is true, can you imagine?!
Anyone who has arrived in Bristol since 2000 or can't remember the 20th century might raise an eyebrow or two at this, but for many years, as Bristol's docks and industry died a death, the assumption was that the Floating Harbour would be filled in. After all, what was it good for?
In the 1960s there were grand plans for flyovers and ring roads in the sky. Much of Totterdown was cleared away – people's homes and histories – to make way for a ring road that never happened. But there are traces of what was in this grand plan in the form of Plimsoll Bridge and Brunel Way, at the far west end of the famous old waterway.
In 1969, there was a plan to fill in much of the Floating Harbour – note the roads and junctions that would take its place, and again in the 1970s. In the 1980s, a plan to fill it all in and turn it into a ring road was defeated at the council by just six votes. That vote was the turning point, and in the 90s developers moved in and began converting the old warehouses to flats, and the Canon's Marsh regeneration, which included @Bristol and Millennium Square, secured its future.
It's a thing you hear people say as they saunter into the rather lovely Victorian covered shopping arcade in Clifton, and it's probably come from the fact it is one of the first of its kind: but it is a long way from being the first centre.
The little arcade houses 17 shops now and opened originally in 1878. But that was during the height of the new fashion for shopping as a leisure pastime, and arcades like this were opening up everywhere. Going back into history, the Romans and Ottomans had covered streets lined with shops - but the first modern arcade, as we understand it, at least in Britain, is the Burlington Arcade in London, which opened in 1819.
Truth factor 8/10: Yes, it leans - but you can't go up it.
The Tower of Temple Church leans by almost as much an angle as the Leaning Tower in Pisa, so it's baffling why there aren't huge crowds of American tourists taking pictures holding up their hand side on to the tower, pretending they are holding it up.
Actually, it'll be because it's surrounded by rather anonymous office blocks and it's hard to get a picturesque shot of the tower where it leans.
But lean it does, by 5ft 5in from the vertical, at an angle only two degrees less acute than the Pisa tower.
It was leaning even as they built it in the middle of the 1400s. They tried to correct the lean as they went up, so the tower is at different angles. The legend is that it was built on woolsacks, but like any of the builders currently constructing new huge towers in this part of Redcliffe, it's the soft river-deposit clay that is the problem. This part is in the inside of the bend of the old River Avon, and the soil here is a deep and soft alluvial deposit. The woolsack legend is almost certainly a metaphor gone astray – most churches in the 1400s were built using money from the lucrative trade in wool that caused an economic boom in the West Country then.
It was gutted by fire during the first major German attack on Bristol in November 1940, and the following day a company of the Royal Engineers came into the city to help with clearing up operations. One of the officers saw how the tower was leaning and decided that it had better be demolished, in case it collapsed. Luckily, Bristolians who heard what he was planning were able to persuade him that the tower had always leaned, and saved it from complete destruction. But it remains a shell, one of the city's memorials to Blitz victims. And although you can walk around the ruins, you can't climb the tower.
Truth factor 1/10: Sadly, no.
It gets a mark of one rather than zero simply because, yes, there is a road in Bristol named Johnny Ball Lane. But it's not the lovably hyperactive maths enthusiast who engaged generations of children to think of numbers in the last years of the 20th century – and had a daughter named Zoe.
No, Johnny Ball Lane, which drops from Upper Maudlin Street opposite the BRI down the steep hill to Lewins Mead, is a narrow path named after John O'Ball, who kept a friary in the neighbourhood. He sounds Irish.
Sheldon Bush and Patent Shot Company works, including the lead shot tower, in central Bristol. this picture was taken in 2002, before the surrounding area was redeveloped.
Truth factor 10/10: Absolutely bang on, and this is amazing.
This is bizarre, but there was a chap called William Watts, who lived in Redcliffe in the 1780s. He reckoned he had a good night's sleep where the principle of making lead shot came to him in a dream.
Until this point, shot – ie, the little pellets that were fired from muskets – were basically chunks of metal that weren't particularly aerodynamic, flew anywhere and that meant duels with pistols could last hours, and civil wars for years.
Mr Watts woke up one morning with the idea fully formed, they said. He built a three storey tower on top of his house, and dug down into the cellar and then into the caves underneath, to prove his theory. Only then could he show that if you pour droplets of molten led from a great enough height they – like raindrops and any liquid really – actually form perfect spheres as they fall. Then, if you have them land in cold water, the molten lead will instantly solidify, and voila, you have a little sphere of metal.
It was genius, and Watts made a fortune, built a bigger shot tower, but later lost that fortune. The original shot tower was on Redcliffe Hill, but is no longer there. A 20th century successor can still be seen in Cheese Lane, near Temple Back.
Infamous pirate and Bristolian Blackbeard. His real name was Edward Thatch, NOT Edward Teach.
Truth factor 4/10: Close - but no fiery, beard-mounted cigar.
Yes, he was a Bristolian. Yes he was the most feared pirate of the great age of piracy, in the 1710s in the lawless Caribbean. Yes, he did indeed put lit fuses in his beard, and terrorise the trading ships and communities from New York to Jamaica. But he wasn't called Edward Teach.
All the contemporaneous reports of him, and the records too, have him down as an Edward Thatch, not Teach. This little mistake of history was brought to light only recently by an American researcher, historian and author called Colin Woodard, who reckoned that someone somewhere dictated a story about Mr Thatch – probably in the fledgling media of the Irish diaspora up in places like Boston, and wrote down 'Tatch' instead of Thatch.
When the 'definitive history of that age of piracy' came to be written around a decade later, the author saw 'Teach' first, and thought 'Thatch' was wrong. It wasn't. Let the records be rewritten, please. Edward Thatch's ancestors came from Bristol and Somerset and one of them would have been a thatcher, not a teacher.
Truth factor 5/10: It was, but the record has now been beaten.
Up in Clifton, in the last year of the 19th century, 13-year-old Arthur Collins batted first for his school house, Clarke's, at Clifton College in an inter-house match against North Town House. They couldn't get him out over the course of four afternoons and by the end, with crowds gathering, he had scored 628 not out.
It stood as a record in a formal cricket match – ie, one played under the rules of cricket, properly umpired and scored – far longer than poor Collins did. He was killed at Ypres in 1914. In fact it stood until only last year when, in January, a 15-year-old Indian schoolboy called Pranav Dhanawade scored 1,009 not out from just 327 balls, playing for KC Ghandi School against Arya Gurukul School in Mumbai.
The highest score in first class cricket is Brian Lara's 501 not out for Warwickshire against Durham in 1994.
A contemporary wood-cut depicting the aftermath of the 1607 flood in the Bristol Channel.
Truth factor 6/10: It was hit by one - but not quite destroyed.
In 1607, a great flood swept up the Bristol Channel, covering the land for miles in deep water. Thousands died. It was noon on January 30, if you're interested.
It was recorded by history but this was the age before newspapers, and reports were largely a bit vague. Historians put it down to some sort of storm surge, coupled with a high tide.
But then, as the 400th anniversary approached, researchers began looking again – both at geological evidence and the contemporary accounts. Both pointed to the flood actually being a tsunami – caused by a medium-sized earthquake in a little fault line off the coast of southern Ireland. Funnelled by the Bristol Channel, it swept up the coast, going far inland with a rush of water 'faster than a horse can run'.
Depictions of what happened to Bristol are largely lost in the slim accounts at the time, and it's clear the Severn Estuary and the Somerset Levels came off worse. But the tsunami almost certainly came up the Avon Gorge and flooded the little city – which would have been the size of somewhere like present-day Midsomer Norton at the time.
And remember, if it happened before, it can happen again.
Truth factor 10/10: And she is not the only person ever to survive the fall, either.
Everyone knows this one, and those who doubt it listen up now, because it is true. Her name was Sarah Ann Henley and she had decided to end it all by leaping from the bridge in 1885, aged just 22.
Why did she decide life was not worth living? According to a newspaper report the following week, she was a barmaid at the Rising Sun in Easton who was engaged to be married to a GWR porter, but he did the callous thing of breaking off their engagement – by letter. She read it, rushed to the bridge and threw herself off. She was wearing a big crinoline skirt, which witnesses said acted like a parachute, and it was enough to slow her fall and also blow her onto the land rather than the water.
Sarah was badly injured and, as she lay in hospital, word spread about what had happened. She became a local sensation and offers of marriage flooded in. Sarah did get married, 15 years later, to Edward Lane, and lived a long and fruitful life. She died at 85, in 1948.
Sarah was not the only person to survive a plunge from the bridge, however. Eleven years later, two young girls, Ruby and Elsie Brown, were thrown off by their deranged father, and survived after being plucked from the water.
* Indebted to the wonderful @WeirdBristol on Twitter. Follow it for more of this sort of fascinating stuff every day.


Grab your goggles and parasols, put on your top hats and corsets, and jump into your airships to head over to the Southern California Railway Museum for an extraordinary, two-day festival celebrating the fantasy, history and ingenuity behind Steampunk. Enjoy festivities geared for the entire family as we pay homage to the Victorian Era, Edwardian science fiction, and the Industrial Revolution.
Bring the family and enjoy workshops, live entertainment and vendors geared toward Steampunk enthusiasts.
Event Details, Vendor Info, and Ticketing Info will be released soon at https://www.oerm.org/ironhorse/.
Iron Horse Tickets Available Soon!
Vendors: Vendor application will be released soon at https://www.oerm.org/ironhorse/.
Vendors may email brucecripe@oerm.org for more information.


Sorry! We are currently sold out of "Essential Oil Starter Kit" Please select another size or sign up for our Wait List to receive stock notifications.
Plant Therapy has created a starter kit that includes a diffuser to help you start your journey of using essential oils.
This set comes with an Aromafuse Diffuser in Wood-Grain Brown or Pearl White and a 10 mL bottle each of 100% pure, undiluted essential oils and synergy blends of Lavender, Lemon, Peppermint, Frankincense Carteri, Tea Tree, Oregano, Germ Fighter, Rapid Relief, Respir Aid and DiGiZen.
These top oils and synergy blends are the perfect products to test the waters of essential oils and see just how amazing they really can be for your life.
Whether you are looking for a synergy to fight seasonal threats, breathe easier or ease aches, an essential oil to help relax, soothe, or give you an uplifting boost - this is a great place to start. The starter kit comes with only the highest quality of essential oils and synergy blends. Try it out to see!
Add any of the selection of essential oils or synergy blends to the Aromafuse Diffuser to enjoy their different aromas and therapeutic properties.
Lemon or Peppermint can be used to uplift and energize the senses. Use Respir Aid during times when sniffles hit, to help breathe easier and clear up congestion. DiGiZen can be used to help ease occasional digestive upset.
This exclusive set features our most popular Plant Therapy Aromafuse diffuser in Pearl White and 10 popular Plant Therapy Essential Oils and Synergies.
10 mL each of Lavender, Lemon, Peppermint, Frankincense Carteri, Tea Tree, Oregano, Germ Fighter, Rapid Relief, Respir Aid and DiGiZen.
always grateful my friend who is a mom has swayed me from the other brand to here. i really love the diffuser since it's very classy and sturdy and not cheap looking. Love the oils as well as they are not too strong and never gives me headaches. I usually get one from overpowering scents. Definitely purchased the oil sets after!
This was my first purchase from Plant Therapy. I think the variety of oils is great for a first timer and the diffuser is the best!


The 2003 Rafto Prize was awarded to Paulos Tesfagiorgis (1947) for his efforts to improve the rights and democratic influence of the people of Eritrea.
From his exile in London, and later in South Africa,Tesfagiorgis has been working for the advocacy organisation Justice Africa, and has spent much time working for agreement among other Eritrean dissidents on a non-violent democratic alternative for Eritrea. He believes that only democratically elected governments have legitimacy, because they are always accountable to the people they govern. For this reason he also abstains from violence. In June 2015 a United Nations Commission of Inquiry accused President Afwerki of systematic, widespread and gross human rights violations that may constitute crimes against humanity.


text:
Home > All Collections > Newest Products > Red Bull Racing Honda RB16B - 2021 Abu Dhabi Grand Prix
Red Bull Racing Honda RB16B - 2021 Abu Dhabi Grand Prix
Or 4 interest-free installments of
Driver Max Verstappen Sergio Pérez Max Verstappen Sergio Pérez
Orders will usually be shipped within 3-5 working days
Limited to 99 pieces per driver
As raced by Max Verstappen and Sergio Pérez at the Formula 1 Etihad Airways Abu Dhabi Grand Prix 2021 in which Verstappen won his first World Drivers' Championship
Over 250 hours to build each model
Built using original CAD designs and paint codes supplied by Red Bull Racing Honda
We are delighted to reveal the Red Bull Racing Honda RB16B at 1:8 scale, as raced by Max Verstappen and Sergio Pérez at the season-defining 2021 Formula 1 Etihad Airways Abu Dhabi Grand Prix. This edition of models, limited to 99 pieces per driver, precisely captures the cars that delivered the first ever Dutch Formula 1 World Champion in Max Verstappen and a first World Drivers' Championship to Red Bull Racing since 2013.
The car that delivered a first championship since 2013, the Red Bull Racing Honda RB16B was an evolution of the double race winning RB16 of the 2020 season. Piloted by Dutch favourite Max Verstappen, in his sixth year with the team, and Mexican Sergio Pérez, who joined from Racing Point, the RB16B proved its mettle, taking the fight to the hybrid-era dominating Mercedes team. Though the team would ultimately be unsuccessful in its Constructors' title aspirations, Verstappen emerged victorious against the reigning Drivers' Champion Lewis Hamilton in an intense season-long battle that came down to the final lap at the final race in Abu Dhabi. It was a season filled with drama, on-track action and controversy, in which Verstappen was ultimately crowned the first Dutch World Champion.
The RB16B was based on the same chassis as the 2020 car, as dictated by the 2021 regulations after the COVID-19 pandemic prompted teams to agree to a series of cost-reducing measures, including a postponement of the new regulations and a majority freeze of the current rules. However, though the car shared its name and under-structure with the previous season's car, the team had made general refinements in every component. Aerodynamic improvements were visible on the nose, the car featured new brake ducts for the front discs, and the bargeboards had undergone further development. The car's floor was reduced by about 100mm towards the rear, as per the regulations. Much of the interest about the Red Bull was focused on the rear of the car, with the team having spent its two development tokens adjusting its gearbox carrier and rear suspension, to improve the car's aerodynamics at the rear end, something of particular importance with the regulation changes made to reduce downforce. The only major difference that could be seen with the naked eye on the rear wing was a new single central pylon support. The 2020 RB16 broke Red Bull tradition with a double-supported rear wing, but with the RB16B the team returned to a more familiar concept.
The real beating heart of the RB16B was the 2021 power unit: the Honda RA621H. After their announcement that they will be leaving Formula 1 at the end of the season, the Japanese manufacturer implemented all their scheduled 2022 changes into the 2021 power unit in an attempt to equalise the performance of their unsurpassed Mercedes competitor. Some features of the RA621H included a notably lowered and more compact camshaft layout, a different valve angle and shorter cylinder bore spacing than its predecessor, effectively creating a significantly smaller engine with a lower centre of gravity. From 2022 onwards, Red Bull managed their own engine development within a new "Red Bull Powertrain" department.
The opening races in Bahrain and Imola set the scene for the season, with two thrilling battles for victory between Verstappen and Hamilton, winning a race apiece. Momentum swung back towards Hamilton and Mercedes in Portugal and Spain, though Verstappen still claimed second place at both to keep on the pressure. Verstappen dominated in Monaco, propelling the Dutchman and his team into first position in their respective Championships. Pérez, meanwhile, scored respectable points in the opening races for his new team, finishing fourth twice and fifth another two times. Verstappen led the standings, for the first time in his career, going into Azerbaijan. His RB16B was dominant, right until a tyre explosion caused him to suffer a terrifying retirement, as he was catapulted into a wall at speed. Hamilton suffered his own brake issues at the restart, leaving the door wide open for Pérez to earn his maiden victory for Red Bull. Verstappen extended his advantage over the first triple-header with a hat-trick of wins of varying styles, beginning with a two-stop strategy in France – passing Hamilton with one lap left – before doubling up in the Styrian Grand Prix, where he led all 71 laps, and dominating once again at the same circuit in Austria.
The British Grand Prix at Silverstone hosted the sport's first-ever Sprint, which saw Verstappen earn pole position after a move on Hamilton into the first corner. However, due the subsequent race, the rivalry between the duo would explode. Battling straight off the line, the pair tussled through the first eight corners before Hamilton attempted an aggressive pass through the inside of the fast Copse corner and contact sent Verstappen spinning hard into the barriers and out of the race. Considered by many to be a racing incident, the stewards decided Hamilton was predominantly to blame, though he shrugged off his punishment for a late victory. The fallout, however, spiralled. The rivalry would never be the same. Pérez struggled through the weekend, having crashed in the sprint race and started the race from the pit lane.
The Hungarian GP saw carnage on the opening lap as Valtteri Bottas ploughed into Lando Norris, who hit Verstappen as a result, causing significant damage to the Red Bull. The Dutchman persevered unlike his teammate, who retired also being collected by Bottas, and salvaged ninth position. After the summer break, Verstappen claimed a controversial victory at a shortened Belgian Grand Prix, before claiming an emphatic triumph in front of an adoring home crowd at Zandvoort. The drama reignited at Monza in race fourteen of the season, as Verstappen and Hamilton collided again, triggering a double retirement. This time, Verstappen was adjudged the aggressor and was punished with a three-place grid penalty for the subsequent race in Russia. There, he recovered from the back of the grid to claim second position. Pérez struggled over these three races, only earning three points thanks to an eighth-place finish in Zandvoort and a ninth in Sochi.
Verstappen outscored Hamilton in Turkey, and then took consecutive victories in the USA and Mexico, gaining a 19-point lead in the Championship. Pérez hit his best form for the season with three consecutive third place finishes, meaning Red Bull were just a single point behind Mercedes, with four races to go. Hamilton and Mercedes were not ready to give up, and responded with three straight victories in Brazil, Qatar and Saudi Arabia. These races were not without their controversy, Hamilton colliding with Verstappen in Jeddah to name one, but all culminated in the rivals heading into the final race level in the standings, for the first time in nearly 50 years.
This fine 1:8 scale model of the Red Bull Racing Honda RB16B is as raced at the Formula 1 Etihad Airways Abu Dhabi Grand Prix by Max Verstappen and Sergio Pérez at Yas Marina Circuit on the 12th of December 2021. Verstappen took a brilliant pole position at Yas Marina but, as was the case for much of the season, would share the front row with Lewis Hamilton. In another provocative contest, no action was deemed necessary when Hamilton cut Turn 6 to avoid/stay ahead of Verstappen but Sergio Perez's heroic tactical defending helped Verstappen keep in touch with Hamilton, whose pace advantage on the day was undeniable. However, in an ending fit for this most chaotic and captivating of seasons, as a late Safety Car period was necessitated after the Williams of Nicholas Latifi crashed into the wall, allowing Verstappen to pit again and attack Hamilton on much fresher tyres on the final lap of the season. The Dutchman passed at Turn 5 to close out victory and, with it, the 2021 World Drivers' Championship title.
Overall, the Red Bull Racing Honda RB1B6 earned eleven wins, twelve further podiums, ten pole positions and eight fastest laps, scoring 585.5 points and winning the 2021 Drivers' Championship.
The Red Bull RB16B is limited to 99 pieces per driver.
This model is one in our Red Bull Racing Honda RB16B Collection.
Discover the Red Bull Racing Honda RB16B Collection >
Elevate your 1:8 scale collection with one of our elegant, harmonious and handcrafted display cabinets, stands or plinths.
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Red Bull Racing Honda RB16B - 2021 Turkish Grand Prix 1:8 SCALE
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Stewart Scott – Voice Production
Stewart's performing career has covered a wide range of theatrical areas, as a singer in opera, musicals and television to being an actor and after dinner speaker.
His roles have varied from the title role in the opera "Macbeth" to Billy Bigalow in "Carousel".
As a highly respected performer of the works of Burns he has toured America and recorded the CD Rom and video of Burns' life "Robert Burns – Caledonia's Bard". He has also written and filmed the docu-drama for Glasgow's Tall Ship "The Glenlee".
He worked regularly for The Council for Music in Hospitals and sang with Scottish Opera for a number of seasons. He directs numerous youth theatre companies around Scotland and regularly takes drama workshops for adults and children. Productions have included "Joseph", "Return to the Forbidden Planet", "Oliver","Wizard of Oz" " Wedding Singer" and "Godspel".
He has worked extensively with various Scottish Opera outreach programmes including their "Baby O" project.
Stewart has been teaching on the musical theatre course since 1998.


Here is the ultrasound photo from 11 weeks at the CVS. We just got the results back and everything turned out normal!!!! So far we are passing all of our milestones with flying colors. Now that I'm nearly out of the first trimester I just wanted to take this opportunity to thank you for all of your help during this process. Being an older mother (39) with a high FSH (18) I was beginning to think my chances of conceiving a child were slim. But with your expert care and guidance with nutrition, herbs and acupuncture, I fully believe that together we lowered my FSH to 11 which enabled me to get pregnant. I also really appreciate your willingness to assist when we decided to go with Clomid and and an IUI. I'm positive that the course of herbs and acupuncture for that cycle helped it become successful. I still can't believe we were successful with our first IUI. Again, thank you for everything and especially for your calming manner during my times of stress and frustration. Acupuncture is definitely the way to go when Western medicine doesn't provide much hope.
My name is Sandra and I live in West Los Angeles. I was referred to Laurie Binder through my OB/GYN. I was treated by Laurie for two months for infertility issues. When I began seeing Laurie, I was depressed and was looking for new hope. She gave that to me. I did not know what to expect when I walked into her office that day…but I soon realized that Laurie was not just going to be my acupuncturist…but some one who listened and cared. I looked forward to my weekly treatments with Laurie. I knew that after each appointment, no matter what I was personally dealing with, that I would feel better after the treatment. I truly believe that the treatment that Laurie provided to me was the key ingredient in achieving pregnancy!
I've been meaning to write for some time; I just wanted to let you know that I'm doing just fine! I'll be six months next week, can you believe it? Our due date is January 29th, and we found out it is a boy. John and I are totally excited! The whole pregnancy thing has been mind blowing – just with the shock of it of course. But somewhere along my fourth or fifth month, something clicked for me. So now I am finally able to relax and really enjoy this pregnancy. It is very funny seeing my body change so rapidly, and I love feeling baby kick around in there; it's just an amazing thing.
I hope you are both doing well, and Laurie, I will be sure to forward a testimonial soon, because I am forever grateful for the gift that you and Christina helped me to receive.
I feel so very fortunate to have met Laurie and been treated by her. I often think back to the first time I stepped into Laurie's office. After months of uncertainty and many of my concerns having gone unanswered by my doctors, I was feeling dejected, frustrated and very anxious. It was so lovely to meet Laurie and to feel listened to. I immediately felt at ease and her calm, confident manner was very healing. With Laurie, I was met with warmth, a sympathetic ear and a reassuring confidence that I would be able to conceive through the help of acupuncture, diet and exercise. I found the course of treatment to be healing on so many different levels. To my great surprise and delight, I found out I was expecting only a couple of months into the treatment. I am now thoroughly enjoying motherhood and often think of Laurie. I am so very grateful to her.
When you are going through infertility, you will try just about anything to get pregnant. Although, I was hesitant and skeptical about acupuncture, I still wanted to give it a shot. So, I started seeing Laurie in March of 2007. From the moment you walk into her office, you feel such a sense of peace and calmness. And that is brought on even more so with her soothing voice and gentle, kind ways. She gives an outpouring of positive support to each and every person.
The actual acupuncture, itself, is not painful at all. She is a master at placing the needles and never allows you to feel pain. After about 30 minutes of blissful napping, I walk out of there on a cloud — so relaxed and carefree.
It was within two short months that she had me ovulating on my own. We soon turned to IVF because of severe male factor issues. It was our first time going through in vitro fertilization (IVF), so needless to say, there was a certain amount of apprehension. However, this is one of Laurie's specialties — a particular acupuncture protocol during the various phases of IVF.
It was a picture-perfect IVF phase. I am now nearly 6 weeks pregnant. I whole-heartedly believe if it wasn't for Laurie and the acupuncture, there is no way the IVF treatment would have gone as smooth or flawless. I will continue to see her through the term of my pregnancy and beyond! She has become my 'security blanket' and I can't imagine going through 9 months of pregnancy without her.
There just aren't enough words in the dictionary to express my gratitude to this woman and her practice. She is truly an angel and I am so blessed that I found her! I highly recommend Laurie Binder to anyone!
I can't thank you enough for all of your help in getting me to this stage. As you know, we had been trying to conceive for almost two years and had two blighted ovum miscarriages before I came to you for treatment in January 2007. Before finding your practice, I had visited two acupuncture/oriental medicine practitioners, one for seven months, and another for four months. Both had been highly recommended to me by others. During that time, I brewed shopping bags-worth of herbs, took herbal capsules, had acupuncture treatments to stimulate ovulation, etc. However, despite all the treatments and expenses, I never felt any noticeable difference in my health.
To my amazement, within 4 treatments and just 2 weeks, I noticed tremendous improvements in my overall health. My energy level increased greatly, and my cycle – which were somewhat irregular and always very long (43 – 50 days apart), shortened to around 33 – 35 days. I also began a new cycle of Clomid (my second, at a higher dosage), and experienced none of the side-effects that I had the first time around at half the dosage.
In less than 2 months of treatment with you, I became pregnant again. This time, under your guidance, the pregnancy is passing its milestones with flying colors. You provided stabilizing treatments when I experienced spotting and later underwent amniocentesis, but most importantly, you provided positive affirmations and calming words to soothe my anxieties. Coming to your office was more like a Zen-spa treatment, rather than a medical experience. I catch the best naps in your office!
Although you know that I can't completely relax (I'm trying!) until the baby is safely delivered (then it will be a whole different set of worries), I am hopeful, optimistic and excited about this pregnancy. I firmly believe that the journey and outcome would not have been as positive if I had not found you, and from the bottom of my heart, I thank you.
When we are ready to try for the next baby, I will be sure to visit you, my earthly guardian angel, again – to put me in the best of physical and mental health for success.
After almost 3 years of "unexplained" infertility accompanied by a slew of eastern and western medical tactics, I was at the end of my rope. I had just completed the first part of an IVF cycle, with 7 eggs retrieved, only to hear days later that none of the eggs fertilized with poor egg quality cited as the reason for this. I was 33 at the time. My husband and I had pre-paid for 2 IVF cycles, so we hoped that a change of meds and ICSI would provide better results the 2nd time around. Meanwhile, I was emotionally devastated, but knew I wanted to take charge of what we knew would be our last big guns fertility treatment. Here's where the story takes a turn for the better. I came across Laurie's Web Site and requested a consultation. Well. Laurie was everything I had been looking for in an acupuncturist and in the hopes of best complimenting the Western treatment I would continue to undergo. Her acupuncture, like her exam rooms, were thoughtful examples of her ability to relax and rejuvenate. She is a fantastic communicator, finally giving me a full Eastern exam and diagnosis as well as a detailed dietary plan of action that I could really work with. My RE recommended I try "fertility blend" and Laurie took this and any other medication into consideration and prescribed (without pushing!) herbs that I would take during the time off period prior to our next IVF, which spanned several months. By the time I began our next IVF, I felt like a different person and I know I owe a great deal of that to Laurie. The results were remarkable. I had always been a not-so-great/poor responder when it came to stims, this time around I produced 17 eggs and, I guess it was a numbers game because we were able to transfer 3 embies (an 8A, a 6A and a 6B). And tomorrow I will be 22 weeks pregnant, amazing. I cannot recommend Laurie strongly enough, she is, simply put, a Godsend.
I first was a patient of Laurie Binder's because I was going through infertility treatments and my body felt out of balance due to the fertility drugs that I was taking. We were getting ready to do a second try of IVF (invitro fertilization). Laurie was recommend to me and I started treatments twice a week. As the treatments with Laurie progressed my IVF doctor could not believe the progress I was making with the drugs. He was truly amazed at how strong and improved my physical state was as opposed to before when I was not under going the Acupuncture treatments by Laurie Binder. I got pregnant and now have a baby boy! After the birth I was very sore and emotionally all over the place. Again, Laurie treated me and I felt my body respond and heal. I am not exaggerating but in one day after the first treatment I felt my swelling go down and my emotional state became calmer. I am amazed at Laurie's intuitive talents and her skills as a acupuncturist. I believe that the healthy birth of my son and my fast recovery after the birth was 100 percent helped and improved by the treatments of Dr. Laurie Binder.
My husband and I were struggling with fertility issues for almost a year when I started seeing Laurie. My hormone levels were out of balance, resulting in my ovaries responding poorly to hormonal signals. Within months of beginning treatment with Laurie, my hormone levels were completely normal. After a few more months of continued treatment, we got pregnant and are expecting our baby in January.
In addition to providing acupuncture treatments and diet and supplement/herbal advice, Laurie's guidance and support was an incredible gift. Dealing with Western medicine, where the answer to every problem seemed to be more drugs and the most invasive treatments, Laurie really helped to put things in perspective and was integral in helping us find the right path for us. The experience, overall, was truly invaluable and I feel blessed to have found and been treated by Laurie.
I visited Laurie for help getting pregnant, and after just three appointments I learned that I'd conceived! I loved Laurie's calm and warm demeanor, and felt very confident in her command of both Eastern and Western medicine. I will definitely see her for treatment of any health issues I might face in the future.
My husband and I tried for over four years to conceive. Our doctor had prescribed three treatments of Clomid to help regulate our ovulation cycle. With our last month of Clomid looming and the prospect of IVF on our horizon I contacted Laurie to see if she could also assist with acupuncture treatments.
Laurie's incredible warmth and her ability to listen to her patient's needs truly enabled a very calming approach to an area of medicine that I had not experienced before.
Within six consecutive treatments, sometimes twice a week during my Clomid cycle, my husband and I found out we were pregnant!
I believe my healing with Laurie was not only with our dilemma of not being able to conceive but also my soul benefited immensely from her treatments.
We are now waiting patiently for our little one to arrive into the world!
I first went to Laurie after 6 months of trying to get pregnant. My doctor had recently diagnosed me as having PCOS. Imagine my relief when Laurie, due to her previous Western medicine training, knew exactly what that meant without any need for me to translate. We quickly got to work and she treated me holistically, from the needles (not as scary as I thought they would be) to my diet to reassuring conversations. She helped me through this challenging time both physically and emotionally. She told me it would take 6-12 months for me to be balanced and my body to be ready. My fertility doctor told me my only option was in-vitro. Imagine our delight when I got pregnant naturally, no clomid, no in vitro, nothing, about 8 months after I started seeing Laurie.
During my pregnancy, I saw Laurie every 1-2 weeks. She helped relieve many of my symptoms, including nausea and swelling. One day she felt my pulses and asked if I was seeing small dark spots – I was. She told me to eat more iron – red meat and spinach. I did and the spots went away. Two days later blood test came back from my OB and told me I had low iron. One of the many times my experience with Laurie was reinforced by Western evidence.
As I neared my due date I got more and more ready to give birth. I have a family history of long labors. I went to Laurie the week before and then three days before my due date to get things moving in a natural way and to (hopefully) avoid the pitocin that had been so necessary for the women in my family. I went into labor the day I was due and gave birth within 3 hours of arriving at the hospital. I truly believe that I dilated so quickly and easily because of the treatment Laurie provided. I tell every pregnant woman I know to go see Laurie, especially if they are overdue!
After I gave birth, I went back to see Laurie several times. My hormones were in serious flux, my body ached, I was overwhelmed and teary (though not sad). Laurie's treatments helped stabilize me and make me feel human again. But it is not just her treatments that are so effective. Laurie is an amazing spirit who truly listens. I feel fortunate to have her in my family's life.
I'm writing to thank you for your incredible work with my wife, Melanie. I have to admit I was not a firm believer in acupuncture/Chinese medicine, but you have changed my entire outlook on the profession.
After nearly a year and a half of trying, Melanie was pregnant exactly 8 weeks after seeing you. I can't convey how much this has changed our lives. Not only do we have a child on the way, Melanie feels much better mentally and physically.
Your work is truly amazing and should never be undervalued.
After two fruitless years trying to conceive, a friend recommended we try acupuncture. We found Laurie Binder's practice and decided to give it a try. My husband and I both had treatments for about a year. At the same time, we started working with a fertility specialist. We were amazed to see my husband's sperm count & motility improve significantly after a few months of acupuncture. Laurie's attitude is very open; we really like that she appreciates and encourages both Eastern and Western methods.
Multiple rounds of fertility treatments and one IVF cycle didn't end up working but, miraculously, after over three years of trying we had a spontaneous pregnancy shortly after we stopped all treatments. Although we'll never know for sure, I am convinced that acupuncture with Laurie got me in balance and prepared my body for a natural pregnancy. We now have a precious little girl and are so thankful for Laurie's care and support!
I went to Laurie for about 6 months for treatment of infertility with an unknown cause. I had undergone 4 IUIs and 1 in-vitro fertilization with no success before I met Laurie. During treatment with Laurie, she helped me alter my diet and adjust a few things in my lifestyle. I noticed that I had more energy, fewer digestion problems, and then after another in-vitro fertilization, I became pregnant. I continued treatment once a week for the first trimester. My dream finally came true and my healthy baby boy was born. I still have 3 embryos frozen from the in-vitro fertilization procedure. (In the previous in-vitro fertilization, I only had a total of two possible embryos.) I appreciated Laurie's medical background as a nurse. Unknown to me, previously, she had worked in my reproductive endocrinologist's clinic. She understands medical infertility treatment, so she is able to complement it better than other acupuncturists with her style of Chinese medicine. I benefited from her suggestions to my diet. Laurie is easy to talk to and has flexible scheduling. I cannot thank her enough. It is without hesitation that I would recommend getting treatment from Laurie if you are choosing to do acupuncture during your infertility treatment.
I am a first-time client of Laurie's and though we had about a month before I started my stimulation regimen, her work has made a marked different in my response – resulting in my first pregnancy at 38 years old! Laurie concentrated on blood flow to the uterus and cutting down on my "dampness" and improvement of egg quality. My FSH which in two previous months were 9.7 and 10.3 dropped with Laurie's help to 6.2 and 7.3 – and that's when the doctor who claimed that there definitely was a dramatic change most likely due to some acupuncture, started me on the IVF cycle.
I knew that I wasn't a high producer of eggs, having done a egg-freeze several years ago, and though I created a similar amount of 6 eggs, 2 were transferred in an IVF on the 6th day. The two eggs were a grade C, but they hung in there, and the doctor called to verify pregnancy over a week later. The doctor herself has said that she's surprised at the results and that there must be something else "at work." It's early on in the pregnancy, and we hope that all goes well and all babies (we have identical twins) are healthy. I am thankful for Laurie's help and expertise and highly recommend her.


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Schueller to Run for House District 58
Small business owner and former State Representative Tom Schueller announced today that he will run for State Representative in the new House District 58. The new district includes all of Jackson County, the eastern part of Jones County, and a small portion of Dubuque County including Cascade.
While serving in the Iowa House he helped lead rebuilding efforts after the 2008 floods as Founding Chairman of the Rebuild Iowa Committee while also serving on the Economic Growth, Local Government, Ways & Means Committees. Tom worked diligently on job creation and local government issues. While in office he passed passed bills to increase minimum wage, provide preschool for all children and supported budget increases for education. Schueller, who retired from John Deere after 30 years, grew up on a Century Farm dairy operation and graduated from Hempstead High School before attending Clinton Community College. Tom and his sons are partners in Schueller & Sons Reconstruction of Maquoketa. He and his wife, Melodie, have three grown children and 8 grandchildren who also reside in Maquoketa.
Tom is active in Sacred Heart Catholic Church, Maquoketa. He is a member of the Knights of Columbus, Fraternal Order of the Eagle, Ducks Unlimited, Pheasants 4-Ever, and the Lions Club. Before serving three terms as State Representative of District 25, he served on the Maquoketa City Council for 11 years, where he was instrumental in the creation of over 500 jobs in the Maquoketa area, led the successful effort to establish the Capitol Improvements Plan for the city and strived diligently to improve the quality of life.
Tom can be contacted at his home address: 503 West Platt Street, Maquoketa, by calling his home phone: 563-652-2926; (cell): 563-357-9905 or via e-mail at: schuellerandsons@qwestoffice.net
By iowahouse|2011-11-10T12:26:04-06:00November 10th, 2011|Candidates 2012, Recent News|0 Comments


Rosalind Lawless was born in Glasgow in 1978 and studied Fine Art Printmaking at Gray's School of Art in Aberdeen from 1999 to 2002. She graduated with a Masters of Fine Art Printmaking from the Royal College of Art, London in 2004. She teaches art part time, and exhibits regularly in Scotland. In 2002 she won the Royal Scottish Academy John Kinross Award culminating in a three month scholarship to Florence. In 2003 she was winner of the Daler Rowney Drawing Prize Royal College of Art, London, in 2004 the Tim Mara Trust Award from the Royal College of Art and in 2005 the Joe Hargan Award Paisley Art Institute, Glasgow. In 2008 and 2009 she was the recipient of the Glasgow Art Club Fellowship Award and Inverarity One to One Travel Award respectively from the Royal Glasgow Institute of Fine Arts, where in 2013 she became elected member. Her abstract compositions consist of layers of silkscreen, paint and pastels and relates to the spaces that inspire her and document the history created through the process of making the work.


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Originalism as a Theory of Legal Change
Harvard Journal of Law and Public Policy, Vol. 38, No. 3, pp. 817-888, 2015
72 Pages Posted: 21 Sep 2014 Last revised: 2 Jul 2015
See all articles by Stephen E. Sachs
Stephen E. Sachs
Date Written: April 16, 2015
Originalism, best understood, is not a theory of interpretation but a theory of our law. Its central claim is that the Founders' law remains good law for us today. And it ought to be defended, if at all, based not on normative goals or abstract philosophy, but on positive features of American legal practice and of our rules for legal change.
A basic assumption of legal systems is that the law, whatever it is, stays the same until it's lawfully changed. Originalism begins this process with an origin, a Founding. Whatever rules we had when the Constitution was adopted, we still have today -- unless something legally relevant happened along the way to change them. We expect assertions of constitutional change to provide this kind of historical pedigree; and a wide variety of approaches -- "conservative" and "liberal," from precedent to post-Founding practice -- are defended as products of the Founders' law. These ordinary practices show an implicit commitment to a deeply originalist premise: that our law today consists of their law, the Founders' law, plus any lawful changes.
What's important about the Constitution, on this account, isn't so much what its text said, but what its enactment did -- what it contributed to American law at the Founding, as preserved to the present day. Rather than look to original intentions, original public meaning, and so on, we should look to the original law -- the law added to our system by the text's enactment, according to the legal rules governing interpretation at the time. This "original-law originalism" helps us to understand, and hopefully to resolve, longstanding constitutional debates: originalists and nonoriginalists ought to disagree about the sources of today's law, while different schools of originalists ought to disagree about the law's content in the past.
The claim that we still take as our own the Founders' law, as it's been lawfully changed, is a claim about current society; it might be true or false. This Article merely argues that, if it is true, it's the best reason to be an originalist -- and, if it's false, the best reason not to.
Keywords: originalism, rules of change, positivism, constitutional interpretation, jurisprudence
JEL Classification: K10
Sachs, Stephen E., Originalism as a Theory of Legal Change (April 16, 2015). Harvard Journal of Law and Public Policy, Vol. 38, No. 3, pp. 817-888, 2015. Available at SSRN: https://ssrn.com/abstract=2498838
Stephen E. Sachs (Contact Author)
Duke University School of Law ( email )
210 Science Drive
HOME PAGE: http://law.duke.edu/fac/sachs


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La ricerca find articoli where soggetti phrase all words 'hypoxia inducible factor (HIF)' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 13 riferimenti
Selezionare un intervallo 1 - 13 (Mechanism, ...)
Hochachka, PW; Lutz, PL
Mechanism, origin, and evolution of anoxia tolerance in animals
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
P.W. Hochachka e P.L. Lutz, "Mechanism, origin, and evolution of anoxia tolerance in animals", COMP BIOC B, 130(4), 2001, pp. 435-459
Yoshida, T; Kuwahara, M; Maita, K; Harada, T
Immunohistochemical study on hypoxia in spontaneous polycystic liver and kidney disease in rats
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
T. Yoshida et al., "Immunohistochemical study on hypoxia in spontaneous polycystic liver and kidney disease in rats", EXP TOX PAT, 53(2-3), 2001, pp. 123-128
Prchal, JT
Molecular biology of polycythemias
J.T. Prchal, "Molecular biology of polycythemias", INTERN MED, 40(8), 2001, pp. 681-687
Birner, P; Gatterbauer, B; Oberhuber, G; Schindl, M; Rossler, K; Prodinger, A; Budka, H; Hainfellner, JA
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas - Itsimpact on prognosis and on neoangiogenesis
P. Birner et al., "Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas - Itsimpact on prognosis and on neoangiogenesis", CANCER, 92(1), 2001, pp. 165-171
Yoon, DY; Buchler, P; Saarikoski, ST; Hines, OJ; Reber, HA; Hankinson, O
Identification of genes differentially induced by hypoxia in pancreatic cancer cells
D.Y. Yoon et al., "Identification of genes differentially induced by hypoxia in pancreatic cancer cells", BIOC BIOP R, 288(4), 2001, pp. 882-886
Ravi, R; Mookerjee, B; Bhujwalla, ZM; Sutter, CH; Artemov, D; Zeng, QW; Dillehay, LE; Madan, A; Semenza, GL; Bedi, A
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1 alpha
R. Ravi et al., "Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1 alpha", GENE DEV, 14(1), 2000, pp. 34-44
Volm, M; Koomagi, R
Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer
M. Volm e R. Koomagi, "Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer", ANTICANC R, 20(3A), 2000, pp. 1527-1533
Minet, E; Arnould, T; Michel, G; Roland, I; Mottet, D; Raes, M; Remacle, J; Michiels, C
ERK activation upon hypoxia: involvement in HIF-1 activation
E. Minet et al., "ERK activation upon hypoxia: involvement in HIF-1 activation", FEBS LETTER, 468(1), 2000, pp. 53-58
Michel, G; Minet, E; Ernest, I; Durant, F; Remacle, J; Michiels, C
Molecular modeling of the hypoxia-inducible factor-1 (HIF-1)
G. Michel et al., "Molecular modeling of the hypoxia-inducible factor-1 (HIF-1)", THEOR CH AC, 101(1-3), 1999, pp. 51-56
Zhang, JZ; Behrooz, A; Ismail-Beigi, F
Regulation of glucose transport by hypoxia
J.Z. Zhang et al., "Regulation of glucose transport by hypoxia", AM J KIDNEY, 34(1), 1999, pp. 189-202
Chiarugi, V; Magnelli, L; Chiarugi, A; Gallo, O
Hypoxia induces pivotal tumor angiogenesis control factors including p53, vascular endothelial growth factor and the NFkB-dependent inducible nitric oxide synthase and cyclooxygenase-2
V. Chiarugi et al., "Hypoxia induces pivotal tumor angiogenesis control factors including p53, vascular endothelial growth factor and the NFkB-dependent inducible nitric oxide synthase and cyclooxygenase-2", J CANC RES, 125(8-9), 1999, pp. 525-528
Graven, KK; Yu, Q; Pan, D; Roncarati, JS; Farber, HW
Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
K.K. Graven et al., "Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene", BBA-GENE ST, 1447(2-3), 1999, pp. 208-218
KRESS S; STEIN A; MAURER P; WEBER B; REICHERT J; BUCHMANN A; HUPPERT P; SCHWARZ M
EXPRESSION OF HYPOXIA-INDUCIBLE GENES IN TUMOR-CELLS
S. Kress et al., "EXPRESSION OF HYPOXIA-INDUCIBLE GENES IN TUMOR-CELLS", Journal of cancer research and clinical oncology, 124(6), 1998, pp. 315-320


The government's proposed changes to laws dealing with those found not criminally responsible for alleged crimes will fuel a stigma and teach Canadians to be afraid of people living with mental illness, advocates said Tuesday.
Representatives from national mental health organizations were on Parliament Hill to voice their concerns with Bill C-54. The news conference tied in with Mental Health Week in Canada.
Chris Summerville, CEO of the Schizophrenia Society of Canada, said the coalition of groups supports the measures in the bill designed to support victims of crime, but the rest of it is flawed.
"We understand the need to protect Canadians from individuals who commit violent crimes however, this bill as it is currently written will not do this," he said. "What this bill has done is to tell Canadians that they should be afraid of people living with mental illness. Fearing people living with mental illness will only set us back."
The proposed not criminally responsible (NCR) reform act seeks to create a new "high-risk offender" designation for those who have been declared NCR because of mental illness. The high-risk designation would be given by the courts, not the existing review boards that currently determine the timing of an accused's release and his or her supervision afterwards.
High-risk offenders could not be discharged until a court agrees to lift the designation; they would not be eligible for unescorted passes into the community and could have their mandatory review period extended from one year up to three years.
The bill also aims to give victims of crimes a greater role by providing them with notification upon a person's release, if it is requested. Those found by a court to be NCR are neither convicted nor acquitted. They are kept at mental health facilities until the review board determines they can be released, sometimes with strict conditions.
The government argues the legislation will keep dangerous people in custody and address the concerns of victims.
But the mental health advocates say the legislation won't help reduce crime and that more support for victims shouldn't have to come at the expense of the rights of people with mental illness.
"This is not an issue of give or take but rather one of working together," said Dr. Paul Fedoroff, a member of the board of directors of the Canadian Psychiatric Association and president of the Canadian Academy of Psychiatry and the Law.
Fedoroff said mental health groups were not consulted during the drafting of this bill and they have not been able to get a meeting with Justice Minister Rob Nicholson directly, only his staff. He said they want to work with the government to try and amend the bill so it more fairly deals with people with mental illness.
A proposal to prevent people from leaving hospital grounds, for example, does not contribute to treatment and recovery or the preparation of people for reintegration once they are released, the advocates said.
They said the language in the bill demonstrates a complete lack of understanding about people living with mental illness. They are also concerned about the wider implications the measures could have.
"It's not just the group of people affected by the bill, it has broader ripple effects," said Peter Coleridge, national CEO of the Canadian Mental Health Association. "There is language in the bill that provide labels that fuel stigma."
"All the progress we've made is now being undermined," said Coleridge.
Summerville said language is important and that he doesn't consider people deemed NCR as "criminals."
"They did not do what they did with a criminal mind. It was mental illness," he said.
The review boards already take into consideration the need to protect the public when deciding if an accused found not criminally responsible is ready for release, and balances that with other factors including the mental condition of the accused, the reintegration of the accused into society and the other needs of the accused.
The government wants public safety to be the paramount concern, placing a priority on the severity of the crime, and for victims' needs to be considered and is changing the current legislation to reflect those priorities.
The groups at Tuesday's news conference are concerned the government is trying to correct a problem that doesn't exist and that the changes are not evidence-based.
Low recidivism rates among those deemed not criminally responsible who are later released show that the review board system is working properly, they said.
"Mental illnesses are treatable, we have the best science today to do that and furthermore recovery is possible," said Summerville.
The advocates are also worried that some lawyers may advise clients not to pursue an NCR defence because the penalties and conditions may be less strict in the regular justice system, which would result in people with mental illness being diverted to jails instead of hospitals.
A spokeswoman for Nicholson was asked to address the concern about stigma. Julie Di Mambro responded in an email by quoting Prime Minister Stephen Harper who said: "When atrocious events do occur and the state fails to act, fails to do all it can do to defend innocent citizens, it violates the inherent trust upon which its existence is justified."
Di Mambro also wrote that the bill's measures are responsible and carefully crafted and "are designed to apply to the most dangerous and egregious of cases."
She also said that the provinces and organizations specializing in the criminal justice system were consulted about the bill.
The government says these measures will only apply to a small number of people and only in cases of serious personal injury but that they are necessary to ensure public safety.


text:
MUSICAL HYDROTHERAPY TRAINING
MUSIC PRODUCTION MODULE
MUSIC HYDROTHERAPY SESSIONS
WHERE WE HAVE WORKED
MUSIC PRACTICE
ADÈLE DRAKE
In establishing three Drake Music UK charities, Adèle pioneered the widening of musical possibilities for disabled people through the game-changing use of technology. In 2010, with composer Joel Cahen, Adèle established Liquid Vibrations and remains a trustee.
MIKE BETTRIDGE
Mike is a registered chartered accountant.
DUNCAN CHAPMAN
Composer and sound artist who regularly works with leading music organisations throughout the world. He is a contributor to courses at De Montfort and York Universities.
JUDITH ROBINSON
Judith Robinson is an experienced arts professional with creative flair and a passion for achieving social justice through engagement in the arts, especially music. Currently Head of Education at Sound and Music, Judith is also a primary school governor.
JULIA JAMES
Julia is Principal and South West Regional Lead, based at the Ofsted rated outstanding Bedelsford School in Kingston, London.
Rebecca is a communications professional and coach who works in the corporate sector.
Clare is a disabled musician and former CEO of Sound It Out Community Music, Birmingham.
& co-founder
JOEL CAHEN
joel@liquidvibrations.org.uk
Joel specialises in recording and designing sound for film, dance, theatre, radio and art productions.
Wet Sounds, is Joel's acclaimed project producing underwater sound installations at swimming pools internationally since 2008.
Creator of We're All Bats. Online and on site listening arts workshops
GEORGINA DENSLEY
georgina@liquidvibrations.org.uk
George has over 12 years experience in designing and delivering creative projects with disabled young people and has previously worked for disability charities including Incredible Kids, CEDA, Hop Skip and Jump South West and spent 7 years leading the Participation Department for international Children's Theatre Company, Travelling Light. Alongside her work at Liquid Vibrations George is co-director of intergenerational Arts charity Wyldwood Arts.
In Memory of STEVE KNIGHT: 03.12.1966 - 27.07.2020
The Board of Liquid Vibrations is saddened to hear of the passing of Steve Knight, one of our longest standing trustees, and an accomplished and pioneering Disabled musician.
Charity co-founder and trustee Adele Drake says:
'I first met Steve Knight when he came to the Drake Music Research Project workshops in Blackheath Concert Halls. This was in the mid-1980s and I think he was 22. His music teacher at Charlton Park School had picked up on the interest he'd shown in music and she was looking for suitable routes for Steve's talents. Self-taught and using his feet on a synthesiser, Steve could play by ear and from memory.
Of the many memorable times that myself and friends have had with Steve, one which stands out in particular was when he was given the red carpet treatment in Iceland. He performed at many major concerts including sharing the stage with Jools Holland and Andy Sheppard in London and Edinburgh. For a number of years, Steve was a tutor to younger disabled musicians at Orpheus Centre, as well as in many Drake Music workshops.
The news of Steve's passing is deeply shocking, and our thoughts are with his family and many friends. His contribution to Liquid Vibrations board has been transformational, and he was a keen and passionate advocate of other disabled people. His sense of pragmatism and shrewdness, was matched by his generosity, humour and warmth, and he will be greatly missed by the many friends he leaves behind.'
Enquiries: joel@liquidvibrations.org.uk
Liquid Vibrations is a charity established in 2010.
No spam, you can unsubscribe anytime


Round 10 saw the WaiBOP Beko side host the Northern Marvels from Auckland for the final home game of the season at the wonderful facilities at Tokoroa Events Centre.
Round 9 saw the WaiBOP Beko side travel to Gore to take on the South team, for the final away game of the season.
After two weeks travelling away, Round 8 saw the WaiBOP team make their first appearance at their new home venue, The Peak, against the Northern Comets.
After a loss last weekend, Round 7 saw a determined WaiBOP Beko team travel to the Trust Arena in Waitakere, to take on the Northern Marvels team.
Round 6 saw another top-of-the table clash, between WaiBOP and Central, this time down at the TSB Arena in Wellington. After a close game back in Round 2, this game was always going to be an exciting encounter.
After a loss to Mainland last weekend, the WaiBOP side were looking to reverse the result this week, in the Round 5 rematch, held at Rotorua Girls High School.


text:
var projects = require('../projects.json')['projects'];

exports.projectInfo = function(req, res) {

	var projectID = req.params.id;
	var project = getProjectData(projectID);
  	res.json(project);
}

exports.view = function(req, res) {
	var projectID = req.params.id;
	var project = getProjectData(projectID);
	res.render('project', project);
}

function getProjectData(projectID) {
	if (projectID == "random") {
		projectID = Math.floor(Math.random() * projects.length) + 1;
	} else {
		projectID = parseInt(projectID);
	}
  	var project = projects[projectID-1]; // of by one, our first project has index 0
  	return project;
}

redpajama_set_name: RedPajamaGithub


Samsung's latest addition in their club of smartwatches, the Galaxy Watch, is turning out to be a bit of a let down for some of its buyers. After spending a good chunk of money, what they are getting in return are skin rashes, burns and even blisters in some reported cases.
The issue has recently been put across by some concerned Galaxy Watch users on Samsung's European help forum. Allegedly both 46mm and 42mm variants of the watch are accused of causing the skin issues.
I received my pre ordered Samsung Gear 46mm 2018 watch on September 7th 2018 and have been wearing it often. Remove it for showering and charging and sometimes I sleep with it. Recently I've noticed this rash developing and it slightly irritates me. The rash area is sore red and it looks like the skin is stretched or burnt. The picture does bit show as clear as seen in person.
I'm experiencing exactly the same thing. I also have the 46mm Bluetooth version. I've had my watch less than a week and I already have a small rash on my wrist in exactly the position of the watch.
I have the same exact problem with my Galaxy Watch 42mm. I am using the rubber arm strap as well. I have a red circle right under the watch where the sensors lays on the arm with a small, not irritated point in the middle (presumably where no nickel or plastic makes contact with the skin. I also have small red and irritated stripes on both sides of my arm where the strap is.
One can empathize that people with sensitive skin are more vulnerable to such kind of allergic reactions. But unfortunately people have clearly mentioned that this is not the first time they are wearing a smartwatch. They reported never having had any such issues with smartwatches from other companies which they used prior.
I've used diver watches before, without any problems, and use stainless steel watches daily for 30years without any issues, and I don't have any contact allergies that I know of.
I wore a Seiko divers watch with rubber band continuously for 3 months during summer, with swimming, working out, and without doing anything to dry either the watch or my wrist, without getting as much as an irritated hair on my wrist. After 10 days with my new galaxy watch, taking it off every second night to charge, i get a rash so bad, that I have to use 5% hydro cortisone to make it heal.
Adding to the aforementioned issue, Galaxy Watch's (both 42mm and 46mm) poor battery performance is another matter that has been brought to light. Users claim they are not getting anything close to the battery backup that Samsung promised.
42 mm black LTE HORRIBLE battery…I get maybe 10 to 12 hours with basic use…i.e. using it as a watch….if I use it for working out 30 min or so, I get about 6 hours of battery life.
I have a 46mm LTE, at 8h 12m I was at 8%. That is with Wi-Fi off, screen brightness 1, always on – off. No working out or anything. Just did a factory reset, about to return mine and cancel the order for my wife. This thing can't even last a work day, much less 7 days. At 50% (little over 4 hours after pulling it off the charger) the app was reporting it was last another 16 hours. This watch is garbage. My 1st gen Huawei watch could last all day with the screen always on.
Is yours LTE? On my LTE 46mm version I'm barely getting 14-15 hours.
About a month back, one of the Samsung representatives assured that the matter was being looked into, and asked the users to share more information however, nothing new has come to light since then.
Unfortunately the issues highlighted in this article are not the only ones ailing the device. Samsung has already acknowledged faulty pedometers and heart rate sensor problems.


Come Emmanuel, to our homes, to our workplaces, and to our churches. Come Emmanuel to our prisons, hospitals, schools, nursing homes, slums, street corners, and to our hearts. God promises when we seek Him, He will come.
To seek. In the Ancient Hebrew, baqash, means "to seek, require, desire, exact, request." Do we seek God in everything we do, every place we go, in every decision we make? Do we require His presence in order to do life or do we trudge along without Him?
Baqash also means "to search for as by touching." When do we search by touch? When we can't see. Tripping through the darkness with hands outstretched to protect ourselves and find our way. Stumbling because we are blinded by the darkness of our own sin and frailty. Grappling in the shadow of our guilt, hands reaching through the blackness until we grasp the One we seek, the One we long for. Jesus. Our Emmanuel.
As traditions states, the Wise Men sought His face, wet with sweat and blood at the manger. We seek His face, wet with sweat and blood at the foot of the cross. So begins our journey with God, a lifetime of searching, seeking and finding as Jesus reveals Himself to those who seek Him.
Seek the face of God this Christmas.
We don't need more Christmas spirit, but Holy Spirit.
Seek His word, His will, His wisdom, His presence, seek Him through prayer and worship.
In order to seek Jesus, we must think of places where He may be found. List a few places or activities in which you can meet with Jesus. Pick one to do today.
Jesus can always be found when we seek Him in His Word. Play the beautiful Christmas music embedded below, get your Bible and read Luke 2. Write down what God speaks to your heart as your seek Him.
Seek Jesus while enjoying His creation. Unplug. Leave the phone at home and just listen to Him.
How will you seek Jesus today? Please comment below.


text:
//
//  ClasssifyViewController.m
//  WeekEndHigh
//
//  Created by scjy on 16/1/6.
//  Copyright © 2016年 scjy. All rights reserved.
//

#import "ClasssifyViewController.h"
#import <AFNetworking/AFHTTPSessionManager.h>
#import "VOSegmentedControl.h"
#import "PullingRefreshTableView.h"
#import "GoodActivityTableViewCell.h"
#import "ActivityDetailViewController.h"
#import "GoodActivityModel.h"
#import "ProgressHUD.h"

@interface ClasssifyViewController ()<UITableViewDataSource, UITableViewDelegate, PullingRefreshTableViewDelegate>
{
    NSInteger _pageCount;
}

@property (nonatomic, strong) PullingRefreshTableView *tableView;

@property (nonatomic, strong) VOSegmentedControl *segmentControl;

//用来负责展示数据的数组
@property (nonatomic, strong) NSMutableArray *showDataArray;
@property (nonatomic, strong) NSMutableArray *showArray;
@property (nonatomic, strong) NSMutableArray *touristArray;
@property (nonatomic, strong) NSMutableArray *studyArray;
@property (nonatomic, strong) NSMutableArray *familyArray;

@property (nonatomic, assign) BOOL refreshing;

@end

@implementation ClasssifyViewController

- (void)viewDidLoad {
    [super viewDidLoad];
    // Do any additional setup after loading the view.
    self.navigationItem.title = @"分类列表";
    self.tabBarController.tabBar.hidden = YES;
    [self showBackButton:@"back"];

    [self.view addSubview:self.segmentControl];
    [self.view addSubview:self.tableView];

    [self.tableView registerNib:[UINib nibWithNibName:@"GoodActivityTableViewCell" bundle:nil] forCellReuseIdentifier:@"cell"];
    _pageCount = 1;
    [self chooseResquest];
}

#pragma mark -----------------UITableViewDatasouce

- (NSInteger)tableView:(UITableView *)tableView numberOfRowsInSection:(NSInteger)section{
    return self.showDataArray.count;
}

- (UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath{
    GoodActivityTableViewCell *goodCell = [self.tableView dequeueReusableCellWithIdentifier:@"cell" forIndexPath:indexPath];
    goodCell.goodModel = self.showDataArray[indexPath.row];
    return goodCell;
}

#pragma mark -----------------UITableViewDelegate

- (void)tableView:(UITableView *)tableView didSelectRowAtIndexPath:(NSIndexPath *)indexPath{
    UIStoryboard *mainStoryBoard = [UIStoryboard storyboardWithName:@"MainStoryboard" bundle:nil];
    ActivityDetailViewController *activityVC = [mainStoryBoard instantiateViewControllerWithIdentifier:@"activityDetailId"];
    GoodActivityModel *goodModel = self.showDataArray[indexPath.row];
    activityVC.activityId = goodModel.activityId;
    [self.navigationController pushViewController:activityVC animated:YES];
}

#pragma mark -----------------PullingRefreshTableViewDelegate

//tableView下拉刷新开始的时候使用
- (void)pullingTableViewDidStartRefreshing:(PullingRefreshTableView *)tableView{
    _pageCount = 1;
    self.refreshing = YES;
    [self performSelector:@selector(chooseResquest) withObject:nil afterDelay:1.f];
}

//tableView上拉加载开始的时候使用
- (void)pullingTableViewDidStartLoading:(PullingRefreshTableView *)tableView{
    _pageCount += 1;
    self.refreshing = NO;
    [self performSelector:@selector(chooseResquest) withObject:nil afterDelay:1.f];
}

//手指开始拖动方法
- (void)scrollViewDidScroll:(UIScrollView *)scrollView{
    [self.tableView tableViewDidScroll:scrollView];
}
//手指结束拖动方法
- (void)scrollViewDidEndDragging:(UIScrollView *)scrollView willDecelerate:(BOOL)decelerate{
    [self.tableView tableViewDidEndDragging:scrollView];
}

//刷新完成时间
- (NSDate *)pullingTableViewRefreshingFinishedDate{

    return [HWTools getSystemNowDate];
}

#pragma mark -----------------CustomMethod

- (void)chooseResquest{
    switch (self.classifyListType) {
        case ClassifyTypeShowRepertorie:{
                [self getShowRequest];
        }
            break;
        case ClassifyTypeTouristPlace:
        {
            [self getSTouristRequest];
        }
            break;
        case ClassifyTypeStudyPUZ:
        {
            [self getStudyRequest];
        }
            break;
        case ClassifyTypeFamilyTravel:
        {
            [self getFamilyRequest];
        }
            break;
        default:
            break;
    }
}

- (void)getShowRequest{
    AFHTTPSessionManager *sessionManager = [AFHTTPSessionManager manager];
    sessionManager.responseSerializer.acceptableContentTypes = [NSSet setWithObject:@"text/html"];
    //演出剧目
    [ProgressHUD show:@"拼命加载..."];
    [sessionManager GET:[NSString stringWithFormat:kClassifyList, _pageCount, @(6)] parameters:nil progress:^(NSProgress * _Nonnull downloadProgress) {
    } success:^(NSURLSessionDataTask * _Nonnull task, id  _Nullable responseObject) {
        [ProgressHUD showSuccess:@"数据加载完成"];
        NSDictionary *dic = responseObject;
        NSString *status = dic[@"status"];
        NSInteger code = [dic[@"code"] integerValue];
        if ([status isEqualToString:@"success"] && code == 0) {
            NSDictionary *dict = dic[@"success"];
            NSArray *array = dict[@"acData"];
            if (self.refreshing) {
                if (self.showArray.count > 0) {
                    [self.showArray removeAllObjects];
                }
            }
            for (NSDictionary *dictn in array) {
                GoodActivityModel *goodModel = [[GoodActivityModel alloc] initWithDictionary:dictn];
                [self.showArray addObject:goodModel
                 ];
            }
            //网络请求是异步请求,若放在请求外面会先执行下面的方法先刷新tableView,在请求完成就不刷新了
             [self showPreviousSelectButton];
        }else{

        }

    } failure:^(NSURLSessionDataTask * _Nullable task, NSError * _Nonnull error) {
//        WXQLog(@"%@", error);
        [ProgressHUD showSuccess:[NSString stringWithFormat:@"%@", error]];
    }];
}
- (void)getSTouristRequest{
    AFHTTPSessionManager *sessionManager = [AFHTTPSessionManager manager];
    sessionManager.responseSerializer.acceptableContentTypes = [NSSet setWithObject:@"text/html"];
    //typeid = 23 景点场馆
    [ProgressHUD show:@"正在拼命加载"];
    [sessionManager GET:[NSString stringWithFormat:kClassifyList, _pageCount, @(23)] parameters:nil progress:^(NSProgress * _Nonnull downloadProgress) {
    } success:^(NSURLSessionDataTask * _Nonnull task, id  _Nullable responseObject) {
          [ProgressHUD showSuccess:@"数据加载完成"];
        NSDictionary *dic = responseObject;
        NSString *status = dic[@"status"];
        NSInteger code = [dic[@"code"] integerValue];
        if ([status isEqualToString:@"success"] && code == 0) {
            NSDictionary *dict = dic[@"success"];

            NSArray *array = dict[@"acData"];
            if (self.refreshing) {
                if (self.touristArray.count > 0) {
                    [self.touristArray removeAllObjects];
                }
            }
            for (NSDictionary *dictn in array) {
                GoodActivityModel *goodModel = [[GoodActivityModel alloc] initWithDictionary:dictn];
                [self.touristArray addObject:goodModel
                 ];
            }
              [self showPreviousSelectButton];
        }else{

        }
    } failure:^(NSURLSessionDataTask * _Nullable task, NSError * _Nonnull error) {
//        WXQLog(@"%@", error);
         [ProgressHUD showSuccess:[NSString stringWithFormat:@"%@", error]];
    }];

}
- (void)getStudyRequest{
    AFHTTPSessionManager *sessionManager = [AFHTTPSessionManager manager];
    sessionManager.responseSerializer.acceptableContentTypes = [NSSet setWithObject:@"text/html"];

    //typeid = 22 学习益智
     [ProgressHUD show:@"正在拼命加载"];
    [sessionManager GET:[NSString stringWithFormat:kClassifyList, _pageCount, @(22)] parameters:nil progress:^(NSProgress * _Nonnull downloadProgress) {
    } success:^(NSURLSessionDataTask * _Nonnull task, id  _Nullable responseObject) {
           [ProgressHUD showSuccess:@"数据加载完成"];
        NSDictionary *dic = responseObject;
        NSString *status = dic[@"status"];
        NSInteger code = [dic[@"code"] integerValue];
        if ([status isEqualToString:@"success"] && code == 0) {
            NSDictionary *dict = dic[@"success"];

            NSArray *array = dict[@"acData"];
            if (self.refreshing) {
                if (self.studyArray.count > 0) {
                    [self.studyArray removeAllObjects];
                }
            }
            for (NSDictionary *dictn in array) {
                GoodActivityModel *goodModel = [[GoodActivityModel alloc] initWithDictionary:dictn];
                [self.studyArray addObject:goodModel
                 ];
            }
             [self showPreviousSelectButton];
        }else{

        }
    } failure:^(NSURLSessionDataTask * _Nullable task, NSError * _Nonnull error) {
//        WXQLog(@"%@", error);
         [ProgressHUD showSuccess:[NSString stringWithFormat:@"%@", error]];
    }];

}
- (void)getFamilyRequest{
    AFHTTPSessionManager *sessionManager = [AFHTTPSessionManager manager];
    sessionManager.responseSerializer.acceptableContentTypes = [NSSet setWithObject:@"text/html"];
    //typeid = 21 亲子旅游
    [ProgressHUD show:@"正在拼命加载"];
    [sessionManager GET:[NSString stringWithFormat:kClassifyList, _pageCount, @(21)] parameters:nil progress:^(NSProgress * _Nonnull downloadProgress) {
    } success:^(NSURLSessionDataTask * _Nonnull task, id  _Nullable responseObject) {
           [ProgressHUD showSuccess:@"数据加载完成"];
        NSDictionary *dic = responseObject;
        NSString *status = dic[@"status"];
        NSInteger code = [dic[@"code"] integerValue];
        if ([status isEqualToString:@"success"] && code == 0) {
            NSDictionary *dict = dic[@"success"];

            NSArray *array = dict[@"acData"];
            if (self.refreshing) {
                if (self.familyArray.count > 0) {
                    [self.familyArray removeAllObjects];
                }
            }
            for (NSDictionary *dictn in array) {
                GoodActivityModel *goodModel = [[GoodActivityModel alloc] initWithDictionary:dictn];
                [self.familyArray addObject:goodModel
                 ];
            }
            //根据上一页选择的按钮,确定显示第几页数据
            [self showPreviousSelectButton];
        }else{
        }
    } failure:^(NSURLSessionDataTask * _Nullable task, NSError * _Nonnull error) {
         [ProgressHUD showSuccess:[NSString stringWithFormat:@"%@", error]];
    }];

}

- (void)segmentCtrlValuechange: (VOSegmentedControl *)segmentCtrl{
    self.classifyListType = segmentCtrl.selectedSegmentIndex + 1;
    [self chooseResquest];
}

- (void)showPreviousSelectButton{
    if (self.refreshing) {//下拉删除原来的数据
        if (self.showDataArray.count > 0) {
            [self.showDataArray removeAllObjects];
        }
    }
    switch (self.classifyListType) {
        case ClassifyTypeShowRepertorie:{
            self.showDataArray = self.showArray;
        }
            break;
        case ClassifyTypeTouristPlace:
        {
            self.showDataArray = self.touristArray;
        }
            break;
        case ClassifyTypeStudyPUZ:
        {
            self.showDataArray = self.studyArray;
        }
            break;
        case ClassifyTypeFamilyTravel:
        {
            self.showDataArray = self.familyArray;
        }
            break;
    }
    [self.tableView tableViewDidFinishedLoading];
     self.tableView.reachedTheEnd = NO;
     [self.tableView reloadData];
}

#pragma mark ----------lazy loading

- (PullingRefreshTableView *)tableView{
    if (_tableView == nil) {
        self.tableView = [[PullingRefreshTableView alloc] initWithFrame:CGRectMake(0, 40, kScreenWidth, kScreenHeight - 64 - 40) pullingDelegate:self];
        self.tableView.dataSource = self;
        self.tableView.delegate = self;
        self.tableView.rowHeight = 90;
    }
    return _tableView;
}

- (VOSegmentedControl *)segmentControl{
    if (_segmentControl == nil) {
        self.segmentControl = [[VOSegmentedControl alloc] initWithSegments:@[@{VOSegmentText:@"演出剧目"},@{VOSegmentText:@"景点场馆"},@{VOSegmentText:@"学习益智"},@{VOSegmentText:@"亲子旅游"}]];
        self.segmentControl.contentStyle = VOContentStyleTextAlone;
        self.segmentControl.indicatorStyle = VOSegCtrlIndicatorStyleBottomLine;
        self.segmentControl.backgroundColor = [UIColor whiteColor];
        self.segmentControl.selectedSegmentIndex = self.classifyListType - 1;
        self.segmentControl.selectedBackgroundColor = self.segmentControl.backgroundColor;
        self.segmentControl.allowNoSelection = NO;
        self.segmentControl.frame = CGRectMake(0, 0, kScreenWidth, 40);
        self.segmentControl.indicatorThickness = 4;
        [self.segmentControl setIndexChangeBlock:^(NSInteger index) {

        }];
        [self.segmentControl addTarget:self action:@selector(segmentCtrlValuechange:) forControlEvents:UIControlEventValueChanged];
    }
    return _segmentControl;
}

- (NSMutableArray *)showDataArray{
    if (_showDataArray == nil) {
        self.showDataArray = [NSMutableArray new];
    }
    return _showDataArray;
}

- (NSMutableArray *)showArray{
    if (_showArray == nil) {
        self.showArray = [NSMutableArray new];
    }
    return _showArray;
}

- (NSMutableArray *)touristArray{
    if (_touristArray == nil) {
        self.touristArray = [NSMutableArray new];
    }
    return _touristArray;
}

- (NSMutableArray *)studyArray{
    if (_studyArray == nil) {
        self.studyArray = [NSMutableArray new];
    }
    return _studyArray;
}

- (NSMutableArray *)familyArray{
    if (_familyArray == nil) {
        self.familyArray = [NSMutableArray new];
    }
    return _familyArray;
}

//在页面消失的时候进度消失
- (void)viewWillDisappear:(BOOL)animated{
    [super viewWillDisappear:animated];
    [ProgressHUD dismiss];
}

- (void)didReceiveMemoryWarning {
    [super didReceiveMemoryWarning];
    // Dispose of any resources that can be recreated.
}

/*
#pragma mark - Navigation

// In a storyboard-based application, you will often want to do a little preparation before navigation
- (void)prepareForSegue:(UIStoryboardSegue *)segue sender:(id)sender {
    // Get the new view controller using [segue destinationViewController].
    // Pass the selected object to the new view controller.
}
*/

@end


text:
Kent State Among Thousands Potentially Hit by Russian Hack
WKSU | By Mark Arehart
Published December 24, 2020 at 5:55 AM EST
Kent State University is among the thousands of institutions, companies and government agencies that have potentially been hit by a cyber-attack linked to Russia. One cyber security researcher says this could end up being one of the biggest hacks in U.S. history.
As many as 18,000 customers may have downloaded tainted software from Texas-based SolarWinds Corp. giving hackers backdoor access to government agencies and scores of sensitive information.
"This is the Hiroshima of cyber security attacks," Professor John Nicholas said.
He studies computer information systems and cyber security at the University of Akron.
"Because SolarWinds is on just about every Fortune 500 company and universities around the world, what they did was they cast a very wide net."
Nicholas said Kent State may not have been a distinct target, but personal information from students and staff, as well as university research, is extremely valuable.
"This is not a short-term hack to get something specific. This is a long-term game to have things planted on machines worldwide to really hurt the United States and the free world."
Nicholas said Kent State's cyber security team will most likely have to check every single computer university-wide for malware.
In a release, Kent State said it was made aware of the SolarWinds breach on Dec. 14, but said there's "no evidence that indicates the hackers used this back door to access the Kent State network."
Kent State Universitycyber attack
Mark Arehart
Mark Arehart joined the award-winning WKSU news team as its arts/culture reporter in 2017. Before coming to Northeast Ohio, Arehart hosted Morning Edition and covered the arts scene for Delaware Public Media. He previously worked for KNKX in Seattle, Kansas Public Radio, and KYUK in Bethel, Alaska.
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Are the 2020 Holidays the Perfect Time to Embrace the Radio Drama?


For the topical treatment of chronic open-angle glaucoma.
Demecarium is a long-acting cholinesterase inhibitor and potent miotic. Because of its toxicity, it should be reserved for use in patients with open-angle glaucoma or other chronic glaucomas not satisfactorily controlled with the short-acting miotics and other agents. Application of demecarium to the eye produces intense miosis and ciliary muscle contraction due to inhibition of cholinesterase, allowing acetylcholine to accumulate at sites of cholinergic transmission. These effects are accompanied by increased capillary permeability of the ciliary body and iris, increased permeability of the blood-aqueous barrier, and vasodilation. Myopia may be induced or, if present, may be augmented by the increased refractive power of the lens that results from the accommodative effect of the drug.
The oral LD50 is 2.96 mg/kg in the mouse. Symptoms of overdose include nausea, vomiting, abdominal cramps, diarrhea, urinary incontinence, salivation, sweating, difficulty in breathing, bradycardia, or cardiac irregularities.


Our new Brown Houndstooth jacket is made up in our signature Balloon fabric with a soft, luxurious hand. Get all of the appeal of tweed without the heavy weight and scratchy hand. This will be your go-to jacket of the season.
Our signature jacket series was developed for ultimate comfort. We wanted a fabric with the ease of jersey, but without the wrinkling and bagging. The result is 'Balloon': 100% wool fabrics that are woven with a natural stretch for comfort and are extremely wrinkle resistant, allowing the jackets to retain their shape.
Model TAJ-02F is cut slim with elegant detailing. We recommend taking your normal size for a modern fit, or one size up for a more classic look.


It if is exam season, then it must be paper leaks, unfortunately that is the reality of the academic scenario in our country. The Bhiwandi police are on the lookout for more accused in the SSC paper leak case.
Those involved included an advocate, who is the parent of an SSC student, who got his daughter's teacher to leak the question paper so that she could secure good marks in the exam.
This paper's report followed a March 24 report which had cited the arrest of a teacher at a school in Bhiwandi who is one of the main accused in the case.
This seems to be a substantial nexus with tentacles spreading wide and a lot of players involved in the case. It is disappointing but expected that 'leak' methods get more sophisticated in these days of social media and the culprits get harder to catch.
Those tracking these cases need to update their methods to keep up with the technology of the times. As it becomes even more difficult to keep question papers a secret, like many things these days because of the nature of the times we live in, it is of utmost importance to move several steps ahead of the cheats.
The strictest punishment should be meted out to those who are facilitators in the cheating scandal. Particularly shocking is the fact that teachers themselves are leaking papers; they should be caught, exposed and blackballed so that they never get a teaching position at any institution again.
Drill it into the kids' heads that by cheating they are fooling nobody but themselves. The cheating criminals are also depriving those who want to succeed by honesty and merit. The adults who should lead by example, are the blackest blots in a system that needs cleaning up in so many aspects.