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Volunteers Needed For New Computer Lab
Written by Admin on May 11, 2010 . Posted in The Salvation Army
Community support was overwhelming when the new Hospitality House held a grand opening in January. Volunteers are now needed to help children in the shelter's computer lab and media center. Photo by Chris Sloan
Salvation Army Cadets Ryan and Marjorie Miller explain the Salvation Army San Bernardino Corps' plans for the new computer lab at its Hospitality House shelter. Among those hearing the plans, in background, are Assistant County Superintendent of Schools Margaret Hill and Brenda Doughty, who directs the tutoring program at Hospitality House for the San Bernardino City Unified School District. Photo by Chris Sloan
(SAN BERNARDINO, Calif.) The Salvation Army Hospitality House seeks volunteers to work with children in its shelter's media center and computer lab.
"This is a great opportunity for anyone who likes working with children, and who could give one or two hours of their time, one, two or three times a week," said San Bernardino Corps Co-Director Capt. Nancy Ball.
"They would not need to teach or even tutor the children, as we have had a tutoring program with San Bernardino City Unified School District for many years," she said. "The volunteers would simply help the children with their school work."
"We also could use donations of wholesome literature books that elementary school students would enjoy reading," Capt. Ball said. "We have many books already to read to younger children, but we want to encourage those who can already read by providing them with books geared to their age group."
Hospitality House, the Salvation Army's emergency family shelter, moved to its new location on Tenth Street on Feb. 1, after operating for more than two years in the San Bernardino Corps' headquarters building, and for about 50 years prior to that at a now-demolished location on Kingman Street.
The media center and computer lab provides the children staying at Hospitality House a place to study. It is also the new home of the on-site tutoring program the San Bernardino City Unified School District has offered to children in the Hospitality House for many years, dating back to when the shelter was on Kingman Street.
These two rooms of the new Hospitality House received special attention during the remodeling of the building on Tenth Street, as Target had donated a $25,000 grant to help The Salvation Army promote children's literacy. With the grant, it purchased the computers, a television for viewing educational videos and programs, study tables for young and older children, lighting and colorful touches, including a large mural.
To volunteer, call the San Bernardino Corps headquarters at (909) 888-1336 or email nancy.ball@usw.salvationarmy.org
About the Salvation Army San Bernardino Corps
The Salvation Army may be able to provide emergency services including food; lodging for homeless or displaced families; clothing and furniture; assistance with rent or mortgage and transportation when funds are available. The Salvation Army Team Radio Network assists rescue workers and evacuees in such disasters as fires.
The Salvation Army is an evangelical part of the Universal Christian Church, and also offers evangelical programs for boys, girls and adults. One of the largest charitable and international service organizations in the world, The Salvation Army has been in existence since 1865 and in San Bernardino since 1887, supporting those in need without discrimination. Donations may always be made online at www.salvationarmyusa.org <http://www.salvationarmyusa.org> or by calling 1-(800)-SAL-ARMY.


We are a family devoted to agriculture for decades, especially cultivating oranges, with over 90 years of experience in the sector. We produce and sell natural oranges at home, without intermediaries.
Our oranges are grown naturally, ensuring their quality (taste, texture, size), therefore they are selected for numerous prestigious clients and cooks to prepare their dishes.
Our farms are located in Burriana (Castellón) on the Mediterranean, an ideal place for citrus production. The oranges that we offer are produced and harvested in our own farms always using the traditional way of our past generations without sacrificing modern ways of cultivation, being respectful of the environment.
Our goal is to offer quality natural orange so you can savor freshly picked from the tree, no wax or artificial additives that impair its taste or its high vitamin content.


Sandycove Holiday Homes offer the widest choice of caravans for sale in Ireland, we also have two of the only fully qualified gas safe registered engineers for caravans in Northern Ireland.
It is easy to see why Sandycove Holiday Homes is the number one leader in its field. With a professional, dedicated team of service experts including a fully trained siting team, as well as being leading suppliers of static caravans providing caravans for sale throughout Ireland.
What services do Sandycove offer?
Our fully qualified gas safe registered engineers are equipped to deal with any gas problems you may have, as well any servicing of gas appliances.
It is important when looking for a caravan park you are also provided with access to professional and reliable services to ensure that all you have to worry about is enjoying quality time with your family. Let us take care of any repairs or services that you might require.
Sandycove Holiday Homes are fully equipped to carry out repairs throughout your entire holiday home, anything from changing a door hinge to replacing skylights. We are approved repairs for Atlas Leisure Homes, Swift Holiday Homes and Victory Leisure Homes and can also repair any other make of caravan holiday home.
We are also approved repairs of Thistle Insurance and can provide fully comprehensive estimates for insurance claims as well as carry out repairs approved by the insurance company.
Why should I have my caravan gas checked?
As leading suppliers of caravans in Northern Ireland, we would advise with every purchase, that you, a caravan owner, are solely responsible for the gas safety of your caravan. Problems with gas appliance can lead to fires, explosions and CO poisoning. Carbon Monoxide (CO) is known as the silent killer, as it is invisible and has no smell, and can kill quickly.
Whether it's a static caravan for sale Northern Ireland, UK, Europe or anywhere in the world; brand new or used, all caravans should be serviced first and foremost for gas.
It is recommended that you have your gas appliances serviced annually to keep them working safely and efficiently. Think about who uses your caravan and your responsibility towards them. Can you afford not to practice gas safety?
How do I winterise my caravan?
All caravans for sale in Ireland and the UK should come with a holiday home manufacturers guidelines. Always follow the guidelines when winterising your caravan. It is recommended that your holiday home is drained by a professional, and some insurance companies will insist on this.
At Sandycove Holiday Homes, we offer a full professional drain down and reconnect service, which also guarantees the pipework in the interim period. We take care of the full process for you, offering you complete peace of mind, and more time to enjoy your leisure time.


At Midwest Building Supply, we pride ourselves on the products we offer.
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The Midwest Building Supply showroom is located in Goddard, Kansas – just four easy miles west of Wichita.


Panel: Working Remotely - is it right for you?
We are seeking a Power Electronics Staff Engineer for the wireless charging engineering team in our Watertown, MA facility supporting high power electric vehicle applications. Projects will focus on developing products from concept through design, development, verification, release to manufacturing and support with the end goal of delivering cost-effective automotive products.Tasks will include circuit modeling and design, simulation, schematic capture, PCB layout and test. Candidates must be able to work independently in a fast-paced, dynamic, highly technical environment. Candidates should be highly motivated with a deep fundamental understanding of power circuits and high-frequency power conversion concepts up to 20KW.
Defines and develops test plans for EV Wireless Power Hardware and Software Components. Single/Three Phase PFC Wallboxes, Inverters, Rectifiers, Ground and Vehicle Resonators, and WiTricity's Tunable Impedance Matching Network (TMN). Customer GUIs. Wireless Power Transfer, Object Detection, and Position Detection Systems. Executes Tests. Functional, Performance, Regression Testing on Hardware/Firmware. Compliance / Interop Testing against SAE and other Wireless Power Standards. Mechanical Stress/Vibration, Environmental, Fault/Error Handling. Collaborates cross functionally to ensure testing requirements are defined. Specifies, designs, and develops test infrastructure including automated test systems. Supports troubleshooting of technical problems; works collaboratively with engineers and team members to resolve outstanding issues. Ensures defect data base is maintained; generates reports for team members to review. Collaborates with team members on continuous improvement initiatives.
The role of the Salesforce Developer is to develop customized solutions within the Salesforce platform to support critical business functions and meet project objectives, business requirements and company goals. The Salesforce Developer must maintain a flexible work environment to facilitate quick responses to changing project requirements and must innovate ways to meet mission goals successfully. The Salesforce Developer will be responsible for managing daily support and maintenance of the internal Salesforce.com instance and conduct long-term improvement operations to ensure compatibility with evolving business requirements. The Salesforce Developer will interact regularly with an Agile Scrum delivery team, working with Product Management & end users as needed to analyze project objectives and capability requirements. Additionally, this role will collaborate with various internal departments, including software engineering, data science & commercial, to ensure that the Salesforce environment supports needs relating to functionality and performance.


A leading energy service provider in Asia Pac with a variety of commercial and residential products – including heating cooling, electricity & gas, hot water systems, and solar panel installations.
This large energy provider needed a dynamic application to support billing transactions related to Orders, Sales, Installations, and Maintenance of their products and services. Within two months BillingPlatform delivered a solution that fit their requirements perfectly. Their new billing engine provides dynamic product management tools, sales-force integration, customer invoicing, financials, and inventory and logistics management in real-time.
With the BillingPlatform system, the company was able to integrate SalesForce functionality with critical billing and operational processes.
BillingPlatform allows them to define an unlimited product catalog within the system that is maintained by Product Managers for sale. Product managers can utilize both the UI for one-off changes or the platform's bulk loader for mass updates or uploads. The product catalog is synced with Salesforce on a nightly basis so that sales agents and field technicians can quickly utilize product information within the Saleforce app – speeding sales cycles, installations, and maintenance.
The platform provides the company with comprehensive invoicing and financials. Customer account information is sent to BillingPlatform to generate and send invoices and statements in real-time to customer emails after a particular event, such as a sale of a product or service.
This makes it easy for customer service and sales representatives to trigger invoices and obtain payments from customers. All invoices and statements are sent directly to Salesforce so that customer services reps can access them when needed.
Detailed financial reports can be generated based on any entity and time interval within the system at any time and translated for loading into SAP – giving the Finance team insight into the status of their business.
The Platform gives them an efficient order management system that allows suppliers and warehouse owners to create purchase orders, track and receive supplies, and track materials for customer installations – fulfilling client expectations and providing valuable operational information.
The platform allows for automatic or manual creation of purchase orders that can be based on warehouse/hub-configured replenishment thresholds or triggered by work orders that cannot be fulfilled with current warehouse stocks.
RCTI (Recipient Created Tax Invoice) functionality is available for suppliers and allows for the creation of invoices on behalf of suppliers for services rendered by these suppliers.
A leading energy provider now has a dynamic billing platform that provides comprehensive billing and rating functionality and centralizes inventory management, purchase orders, and invoice & statement generation and delivery in an efficient, automated set of processes. The Platform's unique customization capabilities provide them with the exact business scenarios they need quickly and efficiently, making their new billing and support system highly adaptable to change.


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Małgorzata I (ur. 1309, zm. 1382) – królewna francuska i nawarska z dynastii Kapetyngów, suo iure hrabina Burgundii i Artois od 1361 r., hrabina Flandrii, Nevers i Rethel w latach 1322-1346 jako żona Ludwika I, córka Filipa V Długiego i Joanny Burgundzkiej.

Małgorzata urodziła się w 1309 r. jako córka Filipa (brata ówczesnego następcy tronu Francji i króla Nawarry Ludwika Kłótliwego) i Joanny Burgundzkiej, hrabiny-palatynki Burgundii. Miała trzy siostry i jednego brata, który zmarł we wczesnym dzieciństwie. Ze strony ojca jej dziadkami byli król Francji Filip IV Piękny i królowa Nawarry Joanna I, natomiast ze strony matki jej babką była hrabina Artois Mahaut (kuzynka Joanny I).

W 1316 r. jej ojciec wstąpił na tron Francji i Nawarry. Już rok później Małgorzatę zaręczono z Ludwikiem, dziedzicem hrabstw Nevers, Flandrii i Rethel. Ślub odbył się w 1320 r. Z tego małżeństwa pochodził syn Ludwik II.

W 1361 r. zmarł Filip, jedyny wnuk jej starszej siostry Joanny. Nie pozostawił następców, wobec tego Małgorzata została hrabiną Artois i Burgundii. Po śmierci Małgorzaty w 1382 r. tytuły przeszły na Ludwika. Dwa lata później zmarł i Artois oraz Burgundia przeszły we władanie wnuczki Małgorzaty, Małgorzaty Flandryjskiej i jej męża Filipa Śmiałego.

Przypisy

Urodzeni w 1309
Zmarli w 1382
Hrabiowie Burgundii

redpajama_set_name: RedPajamaWikipedia


Hounslow Council has announced its intention to award a Corporate Services Contract to Liberata. The contract will see Liberata deliver a range of services including revenues and benefits assessments, transactional finance, HR administration, and payroll services on behalf of the Council. The initial contract is for seven years, with the option to extend it for a further three years, and is potentially worth up to £75 million.
Liberata has been a trusted partner to the Council since 2005, with its revenues and assessment services achieving excellent results for the Council. Hounslow has achieved a high percentage of council tax and business rate collection rates that are in the upper quartile percentage rate for London with significant reductions in historic arrears. In the last 18 months, Liberata has also overseen the early implementation and rollout of the Universal Credit scheme by DWP [Department of Work and Pensions] as well as the digital transformation of the Council's revenue collection and benefits assessment services.
IT services – provision and administration of the council's revenues and benefits and HR payroll systems.
Liberata will also be providing HR administration and payroll services to potentially 57 of the 75 schools within the borough. Liberata has been providing support to schools for more than 20 years, successfully working across a number of council areas including Bromley, Croydon, North Somerset and Worcestershire.
In total, approximately 90 roles will TUPE transfer from Hounslow Council to Liberata as part of the contract.
Vijay Chandiramani, Chief Operating Officer for Liberata, added: "We are absolutely delighted to continue to develop and expand the strong partnership we have established with Hounslow Council in delivering excellent services to residents and other stakeholders. This partnership will achieve the key objectives set out within the Government Transformation Strategy announced last month [February], which is to enable residents, businesses and other users to have a better, more coherent experience when interacting with government services. Our ongoing innovation, using automation, advanced data analytics and proven transformational frameworks have helped deliver significant productivity and cost savings to a number of local authorities including Bromley, North Somerset and Worcestershire.


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More than 100 Instagram accounts belonging to world leaders are collecting dust
By Keith Nelson Jr.	 February 19, 2016
Among world leaders, President Barack Obama has the most popular Instagram account, with more than 6 million followers. But a study found one-third of accounts belonging to world leaders and other government officials and ministries lie dormant. President Barack Obama/Instagram
What do U.S. President Barack Obama and Iranian President Hassan Rouhani have in common? In real life, maybe not a whole lot, we would guess. But the one thing they share is that both leaders have an Instagram account. From Kenya's Uhuru Kenyatta to Prime Minister Lee Hsien Loong of Singapore, it seems almost every world leader has a presence on the social network. Prime Minister David Cameron of the United Kingdom was the latest to set up an account on February 10. However, according to a study by public relations firm Burson-Marsteller, one-third of world leaders with Instagram accounts do not use the service.
The findings come from the Burson-Marsteller's 2016 Twiplomacy study, which looks at how world leaders and governments leverage social media to engage with citizens. With Instagram, it analyzed 305 accounts belonging to world leaders – which includes not just heads of state, but also government and foreign ministers – of 136 out of 193 member states of the United Nations. The firm discovered that a third of those account have either been inactive for more than a year or never used. (Full list of accounts researched can be found here.)
Inactive or not, the accounts have gained 23 million followers in the past four years, since governments started experimenting with Instagram, the study says. The active accounts have posted more than 76,000 photos that show the leaders and governments in action.
"This study illustrates that governments are ready to communicate across all the key social media platforms," said Jeremy Galbraith, CEO of Burson-Marsteller for Europe, Middle East & Africa, and the firm's Global Chief Strategy Officer. "Each platform has its individual unique selling proposition, but it's clear from our study that Instagram can open up new channels as well as reinforce information conveyed through other networks in a more visual and appealing way. Creativity and the use of image is critical for communicating with impact today, and clearly world leaders know this."
In terms of numbers, Obama's account, which started in 2012, has six million followers, is the most popular. That's nearly three times the number of Russian Prime Minister (and amateur photographer) Dmitry Medvedev, who counts 2.04 million followers, followed by Indian Prime Minister Narendra Modi and the White House account.
President Obama has protected more than 265 million acres of land and water—more than any president in history. #FindYourPark
A photo posted by Barack Obama (@barackobama) on Feb 12, 2016 at 5:09pm PST
As for the most effective in user engagement, Obama again takes the lead, with more than 56,000 comments and likes for every post. Modi isn't too far behind, with 42,000, followed by Medvedev. But when you consider which accounts are most active in the number of posts per day, Brunei's Information Department, Kuwait's Foreign Ministry, and Kuwait's Foreign Minister rank in the top-three.
2 миллиона подписчиков. Спасибо за ваш интерес!
A photo posted by Дмитрий Медведев (@damedvedev) on Jan 12, 2016 at 9:15am PST
Interestingly, but not surprising, only 15 of the 305 accounts studied are actually managed by the leaders themselves. Despite the Obama account's popularity, it's actually run by the president's team. Of the top-ten most popular accounts, Medvedev is the only one who manages his account. Burson-Marsteller says Singapore Prime Minister Lee's account is the most entertaining. The study found that the White House account, which features photos from chief photographer Pete Souza, is the one everyone should follow.
Had a quick chat with President Obama during a break at the #USASEAN2016 Summit. The Summit was at Sunnylands, a Presidential retreat at Palm Springs, in California. I thanked President Obama for hosting us and for putting in personal time and effort to engage ASEAN. Looking forward to going home. Long flight ahead! – LHL #USASEAN2016 (MCI Photo by Kenji Soon)
A photo posted by Lee Hsien Loong (@leehsienloong) on Feb 16, 2016 at 5:25pm PST
The increase in world leaders joining Instagram in the past four years reflects the social network's exponential growth over a similar time period. Between January 2013 and September 2015, the number of monthly active Instagram accounts more than quadrupled from 90 million to a record 400 million. Many of the Instagram accounts show the lighter side of government; if only it translated over to the real world.
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redpajama_set_name: RedPajamaCommonCrawl


Wishful Thinking | Carley K.
I can't confirm, but when you leave the hospital with a newborn I'm pretty sure they stuff some super powers in your diaper bag.
The ability to pick out your child's cry in a stadium full of people. The ability to hurl yourself across the room to catch a tipping toddler. The ability to function on less sleep than any other class of human. And the power to know, deeply, when things aren't right with your child.
What we can't do is be in two places at once— if we could, us working moms would be relieved of our most crushing affliction: Mom guilt. If we could be in two places at once, we'd never have to choose between working late and being home for dinner, a sick child and a critical client meeting, a softball championship game and a girl's weekend trip. These are the decisions that make up our lives, and each one feels excruciating.
Imagine if we had, say, an app on our phone that could transport us through time, effectively allowing us to be in two places at once? This is exactly what my good friend Kamy Wicoff (that's her in the cute picture!) imagined in her charming book, Wishful Thinking. It's a tender, modern-day fantasy that blends Harry Potter-style magic with real life.
Wishful Thinking is the story of Jennifer Sharpe, divorced mother of two who feels the pressure to work like she doesn't have kids, and parent like she doesn't have a job. One day her smartphone goes missing, and is mysteriously returned to her with a new app that promises to help her time travel so she can be in more than one place at the same time. Unbelievably, it works, launching her into a year of truly being able to have it all.
3. Tell me in the comments what you would do with the Wishful Thinking app!
This contest ends on Monday at midnight, so hurry and enter— you'll love this book.
If only I could spend the day knitting and playing with my dogs…that's just Wishful Thinking!
Aubrey— I love this. I wish I could knit— it looks so relaxing!
Vicky— that's a good list! Make it happen!
I would use such an app to eliminate ALL commuting time!!
Lynn— Oooh that's a good one. What's your commute like now?
If I had the Wishful Thinking app…I would have no driving time, a full cup of coffee, and the happiest family on earth!
Sarah— you and Lynn are on the same page about driving time!
If I had wishful thinking app I would have no traffics.
Lani— So dangerous, Pinterest is! Why not choose ONE idea to try this month?
I would have one of me for each member of my family, run a fantastic business (or three), travel, use my gym membership, and read everything on my TBR list. And that's just for the afternoon! Lol Divide myself and do all I ever wanted to do? Yes!!! There's an app for that 😉 This book sounds like fun.
If I had a wishing app, maybe I could help all the people standing on the corners with signs asking for any small donation you can give!
Virginia— you are so lovely… what a nice idea.
If I had a wishing app I would play all day with my kids, focus on my college homework, relax with coffee and a book, finally finish painting that room, enter my cat in every local cat show, enjoy being lazy with my husband….and not spend any time feeling guilty about any of it.
🙂 Cat shows!! I entered my American bobtail in her first ACFA show this spring, and she won double champion, so now I'm hooked! haha!
I would slow down my life from the last few years and enjoy every moment including hold back on negative comments and people who should have never stayed long in my life.
Melissa— Wow, that's a good one. Yes, those people we allow to stay in our lives that shouldn't have an invite… toss 'em!
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I love the Farberware stockpot, it is sturdy and it cleans up easily. The stockpot also has a glass lid, so you can check the progress of your meal without having to remove the lid. Plus the polished mirror finish gives this pot and attractive appearance.
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NASA's Newest Recruitment Posters Will Tempt You Work On Mars.
For the last couple of centuries mankind has developed a love affair with the planet Mars. The fourth planet in the solar system may not be the most inhabitable place for animals or people, as the average temperature is around -81℉. Nonetheless, researchers believe Mars was once similar to Earth in terms of weather,.
Scientists have long been in search to find clues of life in the red planet. Their quest to understand Mars may lie in the goal to eventually make this planet a place where people can live in permanently. The general belief is that if there is water, there is life. Mars rover missions have proven there is evidence of past water existence.
To encourage further understanding of Mars, NASA has launched a series of posters encouraging all the planetary aficionados to sign up for the ultimate mission; to live in Mars.
NASA's goal is to eventually set up a whole colony in Mars. To make this a reality, people from all walks of life equipped with skills, knowledge, and talents are needed.
Living in Mars is not the only option, people can choose to live on the planet's moons Phobos or Deimos.
Farmers are needed to grow fruits and vegetables in space.
Those that get the opportunity to move to Mars will be able to explore and study the planet's volcanoes, valleys, and craters.
Mars has canyons and valleys needing up close studying and surveying.
Teachers are needed here too. Learning about the two moons, Phobos and Deimos will be part of the curriculum.
Technicians will be needed to keep all the devices, gadgets working at all times. Constant communication with earth will mean there is no room for failure in its antennas and satellites.
As the population grows so will the need to assemble and construct more homes suitable for this amazing planet.


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Studies: Women really do have more sensitive hearts than men
Dorothy L. Tengler Friday, March 25, 2016
According to French author Henri B. Stendhal, "Since I am a man, my heart is three or four times less sensitive, because I have three or four times as much power of reason and experience of the world — a thing which you women call hard-heartedness."
Stendhal may have been more astute than even he knew. Poets, politicians and psychologists have often argued that women's hearts were fundamentally different from men's, women being the more "sensitive." And while they were referring only to emotions, scientists have recently uncovered gender differences showing women's hearts are indeed more sensitive to certain factors, such as stress.
In the vast majority of cardiovascular diseases (CVDs), there are well-described differences between women and men in epidemiology, pathophysiology, clinical manifestations, effects of therapy and outcomes. Emerging evidence suggests young women are especially vulnerable to the negative effects of stress on the heart, which may result in earlier onset of heart disease or more negative health outcomes if the disease is already present.
For example, CVDs in women and in men over age 45 are the most frequent cause of death in Austria. Every year, 47 percent of the women and 38 percent of the men die from cardiovascular disorders. Known risk factors, such as smoking, increased blood fats, low HDL cholesterol, high blood pressure, diabetes, stomach fat, and lack of exercise are responsible for the increased mortality rate.
Most of those have a much more dramatic effect in women than in men. This is exacerbated by gender-specific risks such as irregular menstrual cycles, early menopause, pregnancy complications (i.e. gestational diabetes or pre-eclampsia) and the pill or hormone replacement therapies.
Diabetes is often an underlying condition for women with CVDs, which significantly increases the risk of a heart attack than in the case of men. Following menopause, blood pressure generally increases, and blood fats and body fat distribution are often subject to adverse changes, also increasing the risk.
Women have different risk factors than men. According to Alexandra Kautzky-Willer, professor for gender medicine of MedUni Vienna, women have a different age distribution along with other clusters of risk factors, and the vascular changes in the heart also differ morphologically.
Furthermore, the diagnosis and therapy are often more difficult. Examinations such as ECG or ergometry are less conclusive. Even the heart attack blood markers in women could be improved with new, specific limit values, and new gender-specific biomarkers could be established.
In case of acute coronary syndrome, women often suffer from a nonobstructive, functional coronary artery disorder and, in cardiac failure, a dysfunction of the filling function of the heart at preserved output performance in comparison with men. The long-term results for both forms of illness have slightly improved, but few studies and guidelines for treatment are available.
To that point, more outpatient rehabilitation services would be beneficial for women who often disregard taking time to rehabilitate after operations or illnesses for fear of neglecting their families or jobs.
Psychosocial stress on the health of women's hearts is a more serious threat than previously thought. The multiple stress factors related to job, household and care of family members cause stress symptoms, which may manifest organically in the heart.
For acute relief, Kautzky-Willer recommends women incorporate periods of rest in the daily routine and get enough exercise to alleviate stress. Studies revealed women benefit from relaxation therapies, such as massages.
Medication has a greater effect in women than in men. For an impending heart attack, physicians may prescribe a statin drug to reduce cholesterol and prevent risky vascular calcification. Women achieve the target LDL cholesterol levels less frequently and often tolerate this medication to a lesser extent than men.
According to Kautzky-Willer, an antibody-based medication in a class that was approved in Europe only last year — PCSK9 inhibitors — could provide a remedy. Although statins prevent the development of LDL cholesterol by blocking a necessary protein, PCSK9 inhibitors stimulate liver cells to increasingly remove LDL from the blood. The medication has to be administered subcutaneously on a regular basis.
There is growing recognition of the importance of emotional stress as a risk factor for heart disease. Compared to men, women have higher levels of psychological risk factors such as early life adversity, post-traumatic stress disorder and depression.
In addition, women are more prone to develop mental problems as a result of stress. Emotional or psychological stress potentially contributes to heart disease in many ways, from influencing heart disease risk factors, to affecting the development of atherosclerosis to triggering heart attacks.
Such stress may impair the recovery, future health and quality of life of patients who have already developed the disease.
Dorothy L. Tengler, MA, is a freelance medical writer/communication specialist with nearly 20 years of experience in the pharmaceutical and medical communication industries. She has developed educational and medical marketing materials, including monographs, slide kits, health articles, primary and review manuscripts, and pharmaceutical sales training materials.
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Russell Slade talks to the press ahead of Saturday's game.
Russell Slade looks ahead to Saturday's visit of Cambridge United to Blundell Park.
Grimsby Town manager Russell Slade says Cambridge United will pose a physical test to the Mariners in Sky Bet League Two this Saturday (3pm).
The U's are unbeaten in three and 11th-placed in the league, and Slade says Shaun Derry's side will present a strong challenge when they visit Blundell Park this weekend.
Speaking on iFollow Mariners, he said: "They hit diagonal balls into their two big strikers, Jabo Ibehre is very strong in the air.
"It's difficult to know what shape he'll come with, because he has changed a few times, he does like to play three in midfield but they're a big, strong, physical side.
"We've watched some of the footage where they went a little bit tighter and stronger against Lincoln, got themselves a very good 0-0 draw there.
And the gaffer praised the team spirit and attitude of his Town squad as they aim to make it seven unbeaten in the league at the weekend.
"Partnerships are beginning to strengthen I feel. As an example, Summers (Luke Summerfield) and Bez (James Berrett) have not lost a game in seven.
"They've been a partnership seven times, they've not lost together so far, so touch wood that continues.
"That's an improving side. The two centre-halves I think have looked very solid in recent weeks so we're pleased with that.
"We're back at home and we'll do everything we can. One thing about this group is it's developing into a strong team spirit with a strong attitude and it gives what it's got, and you can't ask for more than that.
"It's just in that final third, we just need to create enough and get enough quality into areas where we can give ourselves, or somebody else, an opportunity of getting a goal.
"We're gradually improving, and obviously we've just lost that one game in the nine," he said.
Slade began his second spell as Town boss with a 2-1 home win over Cambridge in April, and he's happy with the progress his side have made since then.
He said: "I think it's a team that's improved. Obviously the team that came up that season came up with huge momentum full of enthusiasm, but I think to move forward we needed to make those changes.
"And now we have to move forward again. It was a good game, I remember it well.
The boss also revealed that 19-year-old free agent left-back Jason Akiotu is training with the Mariners, following his appearance in the 2-0 reserves defeat to Mansfield Town earlier this month.
"He's different to what we've got in that he's quite explosive, quite pacy going forward, and he's young – he's only 19 as well.
"Under the rules he's already had two (reserves) games so we will organise probably an extra game for him to play in.
"That's the age group we're looking at to make sure that we've got some good young players coming through, 19, 20, 21-year-olds to back-up so we've got something to work with.
"Reece (Hall-Johnson) has just recently gone out on-loan. He scored a great goal, I went to that game – Chester v Barrow. He scored a great goal from full-back and I was really pleased with his energy.
"It's good for them when they do go out as well and get the football, it's so important.
"I've ensured that with all those boys that go on-loan that we have a call-back in so on the 29th day we've got a 24-hour call-back," he said.
Mitch Rose and Karleigh Osborne were back in training today, following their ankle and hamstring injuries respectively, and will both be assessed tomorrow ahead of Saturday's game.


text:
Assange's speech postponed for security reasons
LONDON. Today is expected Julian Assange to speak from the balcony at the Ecuadorian Embassy in London. Wikileaksgrundaren has now lived for over a year at the embassy. He would have spoken at 15.00 - but Wikileaks has posted on Twitter that's been postponed.
Judges attack Grayling's legal aid shake-up
Price competitive tendering is a 'dangerously inappropriate model' that will damage justice and the courts, critics say The gloves are coming off. With the close of play this week for responses to Chris Grayling's legal aid plans, there has been a rush of blistering criticisms, from Catholic charities to the Law Society; the Bar Standards Board to the Children's Society. No surprise, then, that the Justice Secretary has deployed his trump card: a list leaked to the Daily Mail and The Sun of top-earning legal aid law firms and barristers


text:
Q: iOS "Add to Home Screen" - Delete Data I believe this is the best forum to ask this question.
This issue is with iOS Safari's "Add to Home Screen", and is particularly specific to Google Keep.
I added "Google Keep" to Home Screen through Safari, and after logging in with an email ID (user A), I figured that I needed to login with some other user (user B). Now, Google Keep doesn't have a logout link within the Google Keep interface. Clicking on the signed in user's email address, the "Home Screen app" opens up the Safari browser for further working on that link. In short, there is no way of logging out!
What I have already tried:

*

*Tried deleting the "Home Screen app" and adding it back, fresh! Yet, it holds on to the previous cookie/session, and auto logs in with user A.

*Tried clearing Safari cache and cookie data from iOS settings!

*Tried combinations of the above two.

*Even tried using ?v=2 at the end of the Google Keep URL (https://keep.google.com/?v=2) and adding that to the "Home Screen", but ... the same!!

Is there any way of doing this? Or do I have to manually dig down into the iOS file system and delete the relevant plist or whatever way it's holding this data in?! And if I have to do the latter, can anyone point out which FS file do I exactly need to tackle?
It's for the first time that I am frustrated with iOS, but blame also somewhat falls on Google for not giving a simple logout link in Google Keep (or not having a full-fledged app yet)!!
Please help!

A: 1) Log in to accounts.google.com
2) Login
3) in the Google Dashboard, stop and clear that user
OR
3a) revoke  ALL safari sessions and or Safari enabled Devices presented.
4) reboot iDevice and freshly sign in to Gkeep

redpajama_set_name: RedPajamaStackExchange


The ladies at The White Closet have been keeping a closely guarded secret for some time. But on Wednesday evening, the cat was out of the bag, as they introduced their new collection from The Vintage Wedding Dress Company. With a flagship showroom in London, there are only seven other places in the UK where you can get your hands on a gown by The Vintage Wedding Dress Company – and the beautiful little Burton Road boutique is one of them.
Endorsed by celebrities such as Anna Friel, Kate Moss & Cat Deeley, these are really exquisite designs – and were shown off by two models who kept super-cool in the unseasonal hot, late September weather on the specially designed White Closet catwalk.


6 miles. Depart 7:00 PM from Wissahickon Train Station Parking Lot (Ridge Ave. North of the Falls Bridge.) Come out and do the "'ups" and "downs" of Manayunk on many sets of steps. At the finish, anyone wanting to stop for some liquid refreshment is welcome. No cost for this PA/DCNR hiking week activity. Leader: Paul Piechoski, 215-844-6190.


This former church building is now privately owned. No details are known about the former church. More historical infornation/photographs of the former church/congregation are invited. Photographs uploaded 30/12/2017.


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One of the Biggest COVID Risks Actually Only Affects Men, Study Finds
Here's yet another way that men are disproportionately affected by coronavirus.
By Lauren Gray
Coronavirus has a notoriously wide range of possible outcomes: while many patients survive unscathed with no detectable symptoms, others suffer an onslaught of complications that ultimately lead to death. How each person fares seems determined by how the disease is compounded by risk factors—a long list which includes obesity, according to the CDC. However, a surprising new study published in the journal Annals of Internal Medicine finds that obesity—once considered an equal threat to men and women alike—may only serve as an independent risk factor in the cases of men.
Though many have assumed that obesity contributes to COVID mortality because of its association with conditions like heart disease, diabetes, respiratory conditions, and more, the study concluded that obese men—especially middle-aged men under the age of 60—fared worse than normal weight individuals, even in the absence of these conditions.
To reach this conclusion, the team analyzed the health charts of nearly 7,000 members of the Kaiser Permanente Southern California Health System, recorded between mid-February and early May. Study participants were a median age of 49 years old, racially diverse, and had a mean BMI of 30, with nearly half considered clinically obese.
Notably, researchers found that the risk level did indeed rise along with BMI for patients of both sexes. Those considered "extremely obese," defined as a BMI of 40 or more, were nearly three times more likely to die of coronavirus complications than those of normal weight, and those with a BMI of 45 were over four times more likely to reach a fatal outcome. But as the researchers systematically factored out co-morbidities associated with more severe coronavirus cases, it became apparent that only in men did obesity itself take a significant toll.
Though more research on the topic is necessary, The New York Times reports that it's possible that this gender gap in obesity-related morbidity can be explained by how fat is differently distributed in the bodies of men and women. Men tend to concentrate their weight around the abdomen, and have higher levels of visceral fat, which is associated with higher morbidity rates in general.
Women, of course, are not totally off the hook. Having a higher BMI can still cause the conditions that we know to complicate coronavirus, and maintaining a healthy weight is still associated with better outcomes. As for men, they can add these findings to a growing list of reasons to be extra cautious during the pandemic. And for more on how men are disproportionately affected by COVID, This Is Why Coronavirus Is Killing More Men Than Women, New Study Says.
Lauren Gray
Lauren Gray is a New York-based writer, editor, and consultant.	Read more
Coronavirus • Health Advice • Health Facts
These Are the 6 Main Strains of Coronavirus
COVID-19 has mutated into these different strains of the virus.
This Bad Habit May Increase Your COVID Death Risk
Research shows that this common bad habit could increase your risk of COVID complications.
The CDC Says This State Is Now in the "Red Zone"
"I would look at this data and I would say, 'We need help,'" CDC Director Robert Redfield, MD, warned.


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Jasmine Barnes
Portland Opera: Journeys to Justice
$50 Suggested admission, pay what you will.
These compositions are about love, justice, and experiences of being a Black American. The evening begins with Songs for the African Violet, about the resilience that is demanded of Black women finding joy. We go to Two Black Churches, where we grieve with communities generations apart—both facing the aftermath of murder and hate crimes perpetrated by white supremacists.
In "Your Daddy's Son" we witness a desperate mother's grief and song to her child, and in Night Trip we stop at a gas station with a Black family on a road trip in Jim Crow America. With The Talk we share a coming-of-age conversation that is a matter of life and death, then we celebrate the choice to love—expressed through the words of Rev. Dr. Martin Luther King Jr. in Songs of Love and Justice.
Songs for the African Violet
words and music by Jasmine Barnes
Two Black Churches
Composed by Shawn Okpebholo
"Ballad of Birmingham" text by Dudley Randall
"The Rain" text by Marcus Amaker
"Your Daddy's Son"
from Ragtime
music by Stephen Flaherty
lyrics by Lynn Ahrens
book by Terrence McNally
Night Trip
composed by Carlos Simon
libretto by Sandra Seaton
The Talk: Instructions for Black Children When They Interact With the Police
words and music by Damien Geter
Songs of Love and Justice
by Dr. Adolphus Hailstork
text by Rev. Dr. Martin Luther King Jr.
ABOUT OUR PRODUCTION
Sung in English with English captions.
Approximately 1 hour and 15 minutes, no intermission.
Featuring Portland Opera's Resident Artists—Lynnesha Crump, Jasmine Johnson, David Morgans Sanchez, Michael Parham, and Edwin Jhamal Davis; with limited instrumentation featuring members of the Portland Opera Orchestra, and members of the Portland Opera Chorus.
Digital access will be available for 45 days, starting on April 16, 2021 on our digital channel, Portland Opera Onscreen.
PLAN YOUR WATCH PARTY | CONCIERGE SERVICES
Looking for delivery dining options, a wine pairing suggestion, or a way to plan your watch party? Even though we're working remotely, our team is happy to offer complimentary concierge services. Create your opera experience with the assistance of our Portland Opera Concierge: email Concierge@portlandopera.org or call 503-241-1407, M-W, 10 AM – 5 PM.
Join company members and guests from the production for a post-show Q&A on Zoom following the performance on April 16.
Post-show Conversation
April 16, 2021, 9:00PM Pacific Via Zoom.
RSVP for link: eventRSVP@portlandopera.org
Digital access available for $50 or pay what you will.
Access will be available for purchase in February 2021.
Dates, programming, artists, and details are subject to change.
Resonance Ensemble: Commissions for Now, Part 1
April 21, 2021 @ 3:00 pm – 4:00 pm PDT
After what continues to be a challenging year for the arts, Portland's Resonance Ensemble introduces "Commissions for Now," an exciting new video series that premieres commissioned works from three nationally recognized composers performed by Resonance artists and collaborators and captured by Portland filmmaker Kenny Hamlett.
The series opens Wednesday, April 21st at 3:00pm Pacific, with a piece by the notable choral composer Jasmine Barnes, whose multifaceted works frequently address questions of race and religion. Here she sets the powerful words of social activist and writer Sonya Renee Taylor, in "Normal Never Was," the words that reached thousands of readers in the early pandemic and that Resonance has adopted as its theme for this season, with the permission of Sonya Renee Taylor.
Viewers can view each pre-recorded episode as it premieres on Resonance Ensemble's YouTube channel at youtube.com/c/ResonanceEnsemble. For more information, visit resonancechoral.org/commissions-for-now.
EDITOR'S NOTE: Prepare for this concert by listening to our interview with Katherine FitzGibbon, Damien Geter, Darrell Grant, and Sarah Tiedemann on our podcast.
Resonance Ensemble
info@resonancechoral.org


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Steampunk Cthulhu antho
Antho: Steampunk Cthulhu
Editor(s): Brian M. Sammons & Glynn Owen Barrass
Pay Rate: 3¢ / word + 3 contributor copies
Response Time: variable
Reading Period: now until July 31
Description: The age of steam meets the age of Cthulhu, in a past where technology unbound warps Victorian Britain and the world at large into a dark Steampunk reality.
Submission Guidelines: www.freewebs.com/batglynn/
NOTE: Author D.L. Snell conducted the following interview to give writers a better idea of what the editors of this specific market are seeking; however, most editors are open to ideas outside of the preferences discussed here, as long as they fit the basic submission guidelines.
1) What authors do you enjoy, and why does their writing captivate you?
GB: Gawd there are so many… let's see now! Two favourites: Raymond Chandler, because of his attention to detail and the rawness of his prose, and of course, H.P. Lovecraft, so rich with imagination and darkness, I couldn't imagine a world without his sinister vision.
BMS: Lovecraft, for his original vision of horror. Stephen King for being the first author of adult books I ever read and introducing me to the joys of reading. Robert Bloch and Joe R. Lansdale for doing both bleak horror and black comedy so well. Richard Matheson for being the most consistently good and enjoyable over such a long career. And I can't forget Robert E. Howard for his manly badassery.
2) What are your favorite genres? Which genres would you like to see incorporated into submissions to this market?
GB: My genres, cyberpunk, and horror, for the most part. For this book, with immense clues in the title, we want to see the Cthulhu Mythos mixed with Steampunk, and are quite happy to see elements of fantasy, sci-fi, and even comedy within the subs.
BMS: Horror first and foremost, with various flavours of sci-fi and the occasional sword and sorcery fantasy, as long as it's not too cute and fluffy. As for what I'd like to see for this book, a real blend of Lovecraftian nihilistic and inescapable horror with the often "future is bright" feel of steampunk. Also, I'd like to see some tales outside of the Victorian Britain setting.
GB: I very much like alternate reality settings, whether it be past, present or future. Imagination can really soar when the world and reality have no boundaries.
BMS: I go through cycles. I'll be into historical fiction for a while and then switch to something futuristic. However I always return to stories set in the modern world where reality clashes with the horrific or fantastic.
GB: Any really, though it is good sometimes to read something slow paced, that suddenly goes 'boom' at a mile a minute near the end.
BMS: While arguments can be made for any type of story, the majority of short stories I really like are fast paced. I like the sense of action they impart. Conversely when it comes to novels or horror movies, I prefer creeping dread. Yeah that's weird, I know.
5) What types of characters appeal to you the most? Any examples?
GB: Those that feel helpless against an overpowering Evil/Government/Religion, but fight back nonetheless. Doomed protagonists also read very well in a story.
BMS: I always like strong capable characters that nonetheless come up against things they just can't overcome. It's the whole feeling of yeah, you might be a bad ass (in whatever field) but compared to this you're still nothing.
6) Is there a specific tone you'd like to set in your publication? What kind of voices grab you and keep you enthralled? Any examples?
GB: Dark for the most part, dystopian too. Steampunk tales in a grimy, polluted world with nothing shiny but the glint in the antagonist's eye.
BMS: I'd be happy to run the gambit. From a few (but only a few) silly, humorous tales to the darkest, most feel bad stories imaginable, and everything in between. As long as it's 100% steampunk and 100% Lovecraftian (or would that be 50% of both?) I'll be happy.
7) What is your policy for vulgarity, violence, and sexual content? Any taboos?
GB: Swears are okay, as long as they are part of the story, but I don't see our protagonists lowering themselves to such vulgarities. Violence, no problem where it is a necessary part of the story and not gratuitous. And sex… nothing X-Rated.
BMS: I'm fine with vulgarity; it's a form of expression I'm fairly familiar with, as long as it's warranted. Violence, I like violent horror. While not essential to tell a good story, I grew up in the 1980s reading plenty of splatterpunk. Sex, as long as it's not just tossed in to be titillating and nothing more, I'm fine with it. As for taboos, for me it would be the victimization and sexualisation of children. No one wants to read that, and if you do, then this is not the book for you.
8) What kind of themes are you seeking most in submissions to this market? In general, what themes interest you?
GB: Again, darkness in the Steampunk world, sinister conspiracies and things beyond comprehension breaking through into our reality.
BMS: Technology mixed with black magic or just going too far. Famous characters (fictional or real) from the era would be a good addition, as long as there's a solid reason for them to be in the story. Perhaps pulpy adventure mixed with the darkest horror.
9) Overall, do you prefer downbeat or upbeat endings?
GB: Either, and if it's downbeat for the heroes and upbeat for the bad guys, that's fine! The protagonist discovering the hopelessness of the human condition in the face of the horrors of the Cthulhu Mythos would be a good (but not totally necessary) ending to a Steampunk Cthulhu tale.
BMS: Either, but if I had to lean one way or the other, I'd lean toward downbeat. Not only does it feel more Lovecraftian to me, but I think too many of today's horror stories have happy endings.
10) Any last advice for submitters to this market? Any critical do's or do not's?
GB: DO NOT pay lip service to the Mythos, as in throwing in a few names here and there just to make something Cthulhu Mythos when it's not. We want the stories rich with the elements of both genres, blended seamlessly.
BMS: Let me stress that again, DO NOT play lip service to the Lovecraftian element. I've recently put together a number of Lovecraftian anthologies and you'd be surprised how many authors think that namedropping Cthulhu or the Necronomicon is sufficient. Well it's not. The same should be said about the steampunk genre. If you're not completely comfortable with one side of this genre blending experiment or the other, it will show.
For more scoops, go to www.dlsnell.com.
D.L. Snell writes with Permuted Press. He edited Dr. Kim Paffenroth thrice, John Dies at the End once, and provided a constructive critique to Joe McKinney on his next major novel after Dead City, Apocalypse of the Dead. You can shoot D.L. Snell in the head at www.dlsnell.com.
To reprint this article, please contact D.L. Snell.
Posted by D.L. Snell at Friday, February 10, 2012
Labels: antho, dark fantasy, fantasy, historical, horror, humor, Lovecraft, Market Scoops, mystery, sci-fi, steampunk


Mit ResearcherID zieht Thomson Reuters jetzt nach – Scopus hatte ja schon seit einiger Zeit den Author Identifier im Angebot. Im Gegensatz zu Scopus jedoch kann man in WOS nicht nach der ResearcherID suchen. Dumm, dumm! Gerade das wäre doch ein echter Benefit. Allerdings kann man im Gegensatz zu Scopus (wo man den Support anmailen muss, um die Fehler in den automatisch zugeordneten zig Identitäten korrigieren zu lassen) wenigstens seine "Identität" durch Anfügen von Artikeln quasi selber "rein" halten.
When you register, you are assigned a unique ID number that expressly associates you with your published works, regardless of any possible nomenclature variations or institutional affiliation changes. Unique identifiers allow everyone who accesses ResearcherID to easily find a specific author's work, avoiding the common problem of author misidentification.
ResearcherID is more than an index for accurate author information and publication lists. With the new Web Services tools you can help busy researchers at your institution and increase visibility of their work by creating ResearcherID profiles for them and suggesting publication lists. Then use the download feature to track publication output and properly quantify research performance at your institution.


text:
Q: Can laser-induced graphene wires produce electromagnetic fields if a current is passed through them? For those who don't know, laser-induced graphene (LIG) is a porous type of graphene that appears after exposing certain types of carbon-based materials with a laser.
In this video, they made LIG on Kapton tape using a cheap 400 nanometer laser engraver module. He used the LIG to make supercapacitors, not to make conductive wires. At the end he used the LIG to make a low-voltage heater.
If I took a Kapton wire, turned it into a LIG wire, used the wire to make a coil and passed an electrial current (a DC current), would it generate an electromagnetic field?

A: The current through the coil will produce a magnetic field. The voltage across the coil that pushes the current through the coil will produce an electric field.


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The role of CRISPR in viral diagnostics
By Dr. Tomislav Meštrović, MD, Ph.D.Oct 29 2021Reviewed by Danielle Ellis, B.Sc.
A comprehensive new review paper, published in the journal Viruses, explains in-depth how CRISPR can be utilized as a reliable tool to investigate the viral life cycles – and especially how many new CRISPR systems can be repurposed for diagnostics.
Study: CRISPR Tackles Emerging Viral Pathogens. Image Credit: Nathan Devery/ Shutterstock
Understanding all the complex facets of dynamic association between viral agents and cellular host factors is pivotal to advancing our knowledge of viral entry, replication, and disease mechanisms. Still, these findings may also inform the development of antivirals.
A Nobel Prize award-winning CRISPR genome editing technology has enhanced our understanding of this topic significantly by pinpointing both proviral and antiviral cellular host factors for a myriad of viruses – and most recently for the severe respiratory syndrome coronavirus 2 (SARS-CoV-2), a causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic.
One of the most pertinent questions is: can it be of even better use in curbing this pandemic? Even though we have rather powerful methods of SARS-CoV-2 detection, there are certain issues regarding cost, equipment, turnaround time, and reagent availability. Moreover, can CRISPR be of use for viral diagnostics in general?
What is CRISPR?
This technology represents a defense mechanism of bacteria against invading viruses known as bacteriophages. One of the most known combinations is CRISPR/Cas9 (consisting of enzyme Cas9 and a guide RNA), which can edit genes by accurately cutting DNA and allowing natural DNA repair events to take over.
However, unlike Cas9 (which is a hallmark of CRISPR gene editing), there is also a Cas13 enzyme that can cut the genetic sequence in accordance with targeting information, which then instigates indiscriminate slicing of RNA.
Although this type of behavior can be a big issue when gene editing is concerned, it is a huge advantage in diagnostics since all that cutting can be utilized as a signal that can indicate designated genetic sequences using CRISPR.
CRISPR as a diagnostic tool in virology
This is why CRISPR tests are seen as a way to diagnose infections with the same accuracy as conventional methods, and basically in the same manner as at-home pregnancy tests. In other words, this method holds the potential of increasing our yield in tracking and detecting viral diseases; however, it has not yet been officially approved for this use.
Still, CRISPR has significant advantages, primarily as it yields rapid results in a much more time-sensitive and cost-effective manner. Furthermore, this technology can be easily field-deployable, which is particularly important for low- and middle-income countries.
For now, two main platforms are currently in the development phase: SHERLOCK and DETECTR. In a nutshell, SHERLOCK functions by adding RNA molecules that produce a signal when sliced by Cas13, while DETECTR is similar but uses Cas12 that is activated after it recognizes target DNA.
Both of these platforms have been successfully validated to detect SARS‐CoV‐2 and other (potentially deadly) viruses of human importance, such as influenza A virus, Ebola virus, and lymphocytic choriomeningitis virus, and vesicular stomatitis virus.
From identification to antiviral therapeutics
Such wide adaptation and implementation of CRISPR has revolutionized gene editing and opened a door for the whole new field of screening and viral diagnostic. And naturally, our understanding of the dynamic virus-host relationship, disease mechanisms, and immune response increased in an unprecedented manner.
Hence, this could enable the development of antiviral treatment options in years to come, as further developments in CRISPR technology will reduce undesired off-target effects and allow much easier RNA editing.
And although they are still considered emerging technologies, SHERLOCK and DETECTR are very promising candidates for rapid identification of various infectious disease agents, as these are ultrasensitive tests without the need for complicated processing. We will find out very soon whether they will play a certain role in the COVID-19 pandemic.
Kirby, E. et al. (2021) "CRISPR Tackles Emerging Viral Pathogens", Viruses, 13(11), p. 2157. doi: 10.3390/v13112157. https://www.mdpi.com/1999-4915/13/11/2157
Tags: Bacteria, Cas13, Cas9, Coronavirus, Coronavirus Disease COVID-19, CRISPR, Diagnostic, Diagnostics, DNA, Enzyme, Gene, Genes, Genetic, Genome, Genome Editing, Immune Response, Influenza, Lymphocytic Choriomeningitis, Lymphocytic Choriomeningitis Virus, Pandemic, Pregnancy, Respiratory, RNA, SARS, SARS-CoV-2, Stomatitis, Syndrome, Therapeutics, Virology, Virus
Dr. Tomislav Meštrović
Dr. Tomislav Meštrović is a medical doctor (MD) with a Ph.D. in biomedical and health sciences, specialist in the field of clinical microbiology, and an Assistant Professor at Croatia's youngest university - University North. In addition to his interest in clinical, research and lecturing activities, his immense passion for medical writing and scientific communication goes back to his student days. He enjoys contributing back to the community. In his spare time, Tomislav is a movie buff and an avid traveler.
Meštrović, Tomislav. (2021, October 31). The role of CRISPR in viral diagnostics. News-Medical. Retrieved on January 29, 2022 from https://www.news-medical.net/news/20211029/The-role-of-CRISPR-in-viral-diagnostics.aspx.
Meštrović, Tomislav. "The role of CRISPR in viral diagnostics". News-Medical. 29 January 2022. <https://www.news-medical.net/news/20211029/The-role-of-CRISPR-in-viral-diagnostics.aspx>.
Meštrović, Tomislav. "The role of CRISPR in viral diagnostics". News-Medical. https://www.news-medical.net/news/20211029/The-role-of-CRISPR-in-viral-diagnostics.aspx. (accessed January 29, 2022).
Meštrović, Tomislav. 2021. The role of CRISPR in viral diagnostics. News-Medical, viewed 29 January 2022, https://www.news-medical.net/news/20211029/The-role-of-CRISPR-in-viral-diagnostics.aspx.


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Hire us as your offshore partner, and we can significantly reduce your IT costs.


text:
Q: Unable to get object from promise I have the following code:
const a = {
    Top: {
        fun: () => {
            return {
                sub: {
                    variable: getResponse().then((response) => response)
                }
            };
        }
    }
};

getResponse() returns a Promise.resolve().
I then try to get the value of variable in another file by doing the following:
let test = importedFile.a.Top.fun().sub.variable.then((resp) => resp);

But when I print out the value of test, instead of getting the value of variable, I get
Promise {
  <pending>,
  domain:
   Domain {
     domain: null,
     _events: { error: [Function: handleException] },
     _eventsCount: 1,
     _maxListeners: undefined,
     members: [] } }

I am sure that in the actual const, variable is getting set to the correct value. I'm just unsure of how to access this separately.
My question is unique as the solution to the other question does not solve this problem.

A: Once a value is encapsulated in a Promise, it is not possible to get it back out. This is by design. You are forced to write code that uses the encapsulated value in the context of a .then block. This prevents you from using the value before the asynchronous code has resolved it's value.
let test = importedFile.a.Top.fun().sub.variable.then((resp) => resp);
expect(test).to.equal(resp);

This does not work because test is a Promise<typeof resp>, not typeof resp
You would need to do something like this
importedFile.a.Top.fun().sub.variable.then((resp) => resp)
  .then(value => {
    expect(value).to.equal(resp);
  });

A: That is because you are assigning a promise to your variable. If your getResponse() function returns a promise, chaining with then or catch is still going to return a promise so you can continue to chain functions to your promise. What you are looking for is something like this:
importedFile.a.Top.fun().sub.variable.then(response => {
    // Continue executing code based on the value of this variable...
    // Where 'response' is equal to what you intended 'test' to be from your original post
});


text:
James N. Gardner (born 1946 / died April 10, 2021) was an American professional lobbyist, complexity theorist and graduate of Yale Law School. He was the author of the Biocosm Hypothesis, which argues that intelligent life eventually emerges as the architect of the Universe.

He was a graduate of Yale College and the Yale Law School. He studied philosophy and theoretical biology. He was also an amateur cosmologist, and has published peer-reviewed articles which have been published in Complexity and the Journal of the British Interplanetary Society. He was also a former U.S. Supreme Court clerk and a former Oregon state senator.

Biocosm hypothesis

In the book Biocosm: The New Scientific Theory of Evolution: Intelligent Life Is the Architect of the Universe (2003) Gardner presented the "Selfish Biocosm Hypothesis" in which he says that there is a cycle of cosmic creation, in which highly evolved intelligences with a superior command of physics spawn one or more "baby universes," designed to be able to give birth to new, intelligent life. Thus, the ability of the present universe to support intelligent life as well as it does is not an accident, but the result of evolution in a long chain of the creation of more and more "bio-friendly" universes. Originally presented in peer-reviewed scientific journals, Gardener's "Selfish Biocosm" hypothesis proposes that life and intelligence have not emerged in a series of Darwinian accidents but are essentially hardwired into the cycle of cosmic creation, evolution, death, and rebirth. He argued that the destiny of highly evolved intelligence is to infuse the entire universe with life, eventually to accomplish the ultimate feat of cosmic reproduction by spawning one or more "baby universes," which will themselves be endowed with life generating properties.

See also
 List of law clerks of the Supreme Court of the United States (Seat 8)

References

1946 births
Living people
American lobbyists
Yale Law School alumni
Law clerks of the Supreme Court of the United States
Oregon state senators