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Archive for the 'Divertissement' category
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Remembering Al
Al Reichenberger and I were dog-walking buddies. He favored Labradors. I'm a German Wirehaired Pointer guy. We'd let our dogs frolic off leash and smell the smells of our eastside parks while we discussed matters small and large.
A friendship was built on these casual conversations and small intimacies. I'm honored that Al's family asked me to write his obituary.
Al Reichenberger, a complex man who lived a rich and adventurous life, will be celebrated by his friends and family on Jan. 9, 2022, from 3 p.m. to 7:30 p.m., at the Eno Vino Downtown restaurant. Reichenberger died from cancer on Oct. 19, 2021, at the age of 80.
His likes will probably not be seen again in Madison.
Reichenberger was a raconteur and storyteller, a world traveler, a fiercely loyal family man, an avid pilot, a lover of both fine German cars and Labrador dogs, and the guy you always wanted to be talking with at the party.
But for most Madisonians, Al Reichenberger is remembered as co-owner of The Dangle Lounge, 119 East Main St., with his younger brother, Thomas, and for their many legal battles with City Hall over just how much skin could be safely revealed in a Midwestern burlesque house.
Reichenberger spent 25-plus years in the "gentlemen's club" business before he sold his share to Tom in 1994 and executed a life transition that was unexpected if not astonishing. While wife, Jayne Neuendorf, continued her career at Merrill Lynch, Al settled into being a house-dad for their two sons, Wolfgang and Gunnar.
For a guy raised in the Old World strictures of Deutsch Milwaukee, "house dad" was not an expected life choice, but Al Reichenberger always cut his own path. His parents, Max and Frances Reichenberger, were German immigrants who moved to Milwaukee in the 1920s. His dad was a furrier who began traveling to Germany for various business ventures after World War II.
Al wound up living with German relatives for five or so years, to the point he lost some English fluency. Back in the States, he attended parochial school until his youthful candor became an irreconcilable issue for the school authorities.
Reichenberger was a proud graduate of Rufus King High School in Milwaukee. He joined the U.S. Air Force at 17, served in a bomber refueling station in North Falls, Mont. He later told his boys, tongue in cheek, he was part of our frontline defense protecting Americans from a Canadian invasion.
Politically, Reichenberger was always quite conservative, but he had a strong libertarian streak and did not like to be told what to do, which explains why a military career did not interest him. He told friends that the Central Intelligence Agency had hinted at recruiting him for surreptitious work in East Germany, but Al already had his eye on civilian life. He attended UW-Milwaukee where he earned degrees in business and history and then worked for North Central Air. He came to Madison in 1968 when brother, Tom, opened a bar just off the Capitol Square and needed a partner.
Ah, the Dangle Lounge!
So many stories, many of them even true, have been told about its colorful chapters in Madison history. City officials, urged on by an angry fundamentalist preacher and his flock, tried to close down nude dancing establishments in Madison. The legal fireworks became a show in themselves over the years, as the brothers retained some of the edgiest lawyers around: Percy Julian Jr., Jeff Scott Olson, Sarah Crandall and David Loeffler.
In February 1969, Mayor Otto Festge issued so-called "entertainment guidelines" for strippers and go-go girls, as historian Stuart Levitan details in his book "Madison In The Sixties." The Festge edict went into a highly detailed, almost salacious, description of "the sensual elements" of a woman's body that could not be displayed on stage.
Two weeks later, Levitan recounts Reichenberger led "a protest march of go-go girls in bikinis and winter coats around the Square," as he denounced Festge's rules "as pretty ridiculous."
A few years later, the city pulled The Dangle's liquor license, and the Reichenbergers relaunched the club as The Jazz Workshop, which brought in jazzman Ben Sidran and other musicians. Sidran was playing one night when the great James Brown drummer Clyde Stubblefield, new to Madison, walked in, and they hit it off.
"It was definitely a scene," says Sidran. "The Dangle-Jazz Workshop was sort of a thumb in the eye of the city fathers, and that of course made it attractive to a lot of us."
Indeed, Capitol denizens, irreverent lawyers, hustlers, crooks, lost souls, visiting yokels, and lots of excitable men all populated The Dangle.
Isthmus, Madison's venerable alternative newspaper, was conceived there when bartender Vince O'Hern, a journalism school graduate and Peace Corps veteran, began plotting the new paper with former Capital Times columnist Fred Milverstedt, a Dangle regular.
Eddie Ben Elson, the free spirit, provocateur and lawyer, even announced his candidacy for Dane County District Attorney naked on The Dangle stage. His campaign slogan: "Obey only good laws."
The Dangle legal skirmishing went on for years and only ended when the Reichenbergers agreed to vacate the downtown property and consolidate their operations at Visions, 3554 E. Washington Ave. Olson, the attorney, points out the city attorney's office forgot that the deal was supposed to end after five years, which set the stage for Visions to operate for decades longer.
Reichenberger's great passion was traveling for skiing and adventure. To Switzerland, Austria, Spain, Italy and Germany. "The dollar was so strong it was cheaper to fly to Innsbruck, Austria, and ski there than go to Aspen, Colorado," says Casey O'Keefe, who first met Reichenberger on a crowded Van Galder bus to O'Hare for a ski trip.
All the better both men were car aficionados. Early on Al had Jaguar XK120s and then Porsches and BMWs, says O'Keefe. On a trip to Stuttgart, Reichenberger bluffed their way into a Porsche factory tour and wound up test-driving a Porsche at "full throttle open" on the Autobahn.
"I know, because I had to do the math in kilometers. It was 148 mph," O'Keefe says, and then follows up with a hair-raising tale of their impromptu bobsled run in Salzburg.
"Al liked adventure," O'Keefe attests. Wolfgang and Gunnar make the same point. Their dad was always pushing the limits. He took up snowboarding at the age of 52. At 65 he learned to barefoot water ski.
To look back at Al's life is to see that he lived the famous American imperative as laid out by Henry David Thoreau in Walden: He "wanted to live deep and suck out all the marrow of life."
Al did just that.
The Jan. 9 celebration of Alfonse Reichenberger's well-lived life will take place 3 p.m.-8 p.m. at ENO VINO DOWNTOWN, 1 N. Webster St. That's one block from the Capitol on the 10th floor of the AC Hotel.
Besides Jayne and their sons, Wolfgang and Gunnar, Al is survived by his brother Thomas' three children, Thomas Jr., Elena and Zachary. Tom Reichenberger died on March 13, 2019, at the age of 75.
Friends who wish to memorialize Al's passing are asked to contribute to the Agrace Foundation, which cared for Al in his final days. He succumbed to squamous cell and multiple myeloma cancers.
Categories: Divertissement
Tags: Al Reichenberger, Ben Sidran, Casey O'Keefe, Stuart Levitan, The Dangle Lounge, Vince O'Hern
Cocktail Revelations
I've been working on and off for months on a major writing project. I think it will be a big thing. But, sorry, this story has nothing to do with it. Nope, this one is all about the pleasures of drinking Boulevardiers and fat-washed martinis with your friends. Also in reading Kingsley Amis' earnest defense of social drinking in his magnum opus, Everyday Drinking. Not to mention I report on the good Oxford scholars who emphasize the "social" in social drinking:
Dear readers, put down your phones! Science says you should drink with your friends. Seriously. I have in my hand the printout of "Functional Benefits of (Modest) Alcohol Consumption" written by seven Oxford University researchers. They say that drinking with your buds at the local pub may be linked to an improved sense of well-being.
Okay, that's not exactly a big surprise. But confirming the obvious is what college professors sometimes do. And I know you're thinking what I'm thinking: Just how do I get a piece of this research money? But the investigators also found, according to Oxford publicists, "that people who have a [pub] that they visit regularly tend to feel more socially engaged and contented and are more likely to trust other members of their community" while those who don't "had significantly smaller social networks and felt less engaged with, and trusting of, their local communities."
Yes, it's the fellowship (and sistership) of drink.
Oh, there's so much more in my story. Including revelations that could change your life! (Or not.) Go here for more.
Categories: Divertissement, TheDailyPage.com/Isthmus
Tags: Brian Haltinner, Chris Berge, Julie Bates, June's, Kingsley Amis, Thistle, Thor Messer
I'll Drink To That
I've always liked the camaraderie of sharing a good drink with friends and family. It's one of life's pleasures. Work hard, take care of business. You got to do all that. But these off-duty moments while sharing casual talk and small intimacies are experiences I savor.
All the better I can report, Dane County is in the midst of an unprecedented burst of creativity in brewing, distilling and winemaking. Lots of opportunities, in other words, for folks like me to share the fellowship of an adult beverage.
As I wrote in an Isthmus cover story:
Just go strolling on Madison's near east side. Late this fall I was out walking the dog one night when I stumbled upon — in a tucked-away industrial court — the brand new $1.2 million State Line Distillery, 1413 Northern Court. Glory! Founder John Mleziva even allows dogs in the tasting room. (And quite the room it is: An artfully designed space with weathered barn lumber and a great piece of abstract art representing whiskey making by Madison's Leslie Smith III.)
As Fred Swanson points out, a Madison "Beverage Row" is busily taking shape on the east side. A 15-minute walk from State Line sits the Old Sugar Distillery tasting room, 931 E. Main St., which offers a full sampling of its whiskey, rum, brandy and specialty spirits. Or how about perambulating to Bos Meadery, 849 E. Washington Ave., for its fermented honey drink? As for craft breweries, you can't swing a dead cat on the east side without hitting a growler: I count 10 eastside craft beer tap rooms.
Drive a little farther out and you find Dancing Goat Distillery in Cambridge and Driftless Glen Distillery in Baraboo. And if you head south or go west in Madison and Dane County it's more of the same. Lots of brew pubs, a smattering of distilleries and more wineries than you would think possible in our cold climate.
Hey, it's a good thing. And not just because Wisconsinites enjoy a good buzz. Whether it's a distillery, brewery or winery, all of these makers are idiosyncratic, specific in their missions, and forceful in staking a claim to the Wisconsin terroir. Yeah, it gets down to our identity. And when you consider how so much of small town Wisconsin didn't share in the economic recovery, and is losing its best and brightest young people to big cities, championing local identity seems no small matter.
Brian Cummins, who founded Great Northern Distilling in Plover, near Stevens Point, makes this case. He points out how Great Northern is one of six beverage makers in the Central Wisconsin Craft Collective producing beer, wine and spirits — all within a 30-minute drive of one another in Point, Plover, Amherst and Rosholt.
Take the tour. They're proud of their work.
"We're part of the new creative community," says Cummins, underlining how quality of life goes up for everyone in a region when there are such artisan producers. "It's something to point to that makes their towns unique."
Creative placemaking is what keeps young people in the community, he adds. "For us in central and northern Wisconsin, we need to maintain our millennials. It just can't continue to drain to Minneapolis, Madison and Milwaukee."
To read more (and to learn how a great tasting event called Distill America has led the way), please go here.
Tags: Adam Casey, Distill America, Fred Swanson, Great Northern Distilling, J. Henry & Sons, Old Sugar Distillery, Stage Line Distillery, Three Tier System, Yahara Bay Distillers
Death Of A Friend
Memory is mutable. It fades. Grows fuzzy. Plays tricks. Disappears. Writing is one way to hold on to meaning. Sometimes for dear life. I wrote this remembrance of David Medaris in a red heat after learning of his death. I could close my eyes and see and hear David. As if he was there. I'm glad I got it down. The piece begins:
Isthmus has always been a collection of odd and compelling characters. None more so than David Medaris, who began writing for the paper as a West High student and who spent almost three decades as the listings editor and then a staff writer.
I was editor. David was David, which is to say he cut his own path. As the arbiter of listings, he functioned like a human algorithm. He precisely sorted and summarized hundreds of disparate and often recondite events that poured into the paper each week. No monk in a priory had a more exacting system of categorization.
David lived and breathed by his rules. Yet, paradoxically, he was also an exuberant, free-range thinker. He spied life's complicated facets like a jeweler with a headlamp. Here was the reporter who would ponder endless questions for a story. David had to know. He had to understand. He was immensely curious about life and people. There was a sense of wonder and pleasure in comprehending both the mundane and the profound.
He also had a little sign on his desk: "Just tell the story."
That was David: Painstakingly diligent, yet the faraway flutter of a butterfly in the Amazon might set him off on an intellectual ramble in the Isthmus lunchroom. He took delight in it.
His death Oct. 18 at age 57 after many years of beating back brain cancer was like a kick in the guts to his friends. His love affair with his wife, Michana Buchman, Isthmusassociate editor, was something any of us would want in this life. He always spoke of her with a tone of awe and respect. If only all of us could be so considerate of our partners. Now he's gone.
To read more, please go here. The layout includes a marvelous portrait of David by the great photographic team J. Shimon & J. Lindemann.
Tags: David Medaris, Tom Laskin
Neil deGrasse Tyson Would Dig This
The tech world's hard split between information technology and biotechnology is perplexing. Despite their kindred values, these really smart people seem to live in parallel universes. I found myself puzzling over this last year while attending the International Bioethics Forum sponsored by Promega's educational institute. Despite a stirling assemblage of speakers on the nature of creativity, none of those brainy ITers seemed to be present.
Perhaps this year's topic at the forum will draw some venturesome folks from the software world. Here's how Promega founder Bill Linton describes this year's convocation:
When we recently talked, Linton explained that the annual forum always picked topics — What is the nature of life? What is the nature of death? — in which the answers weren't settled. "Sometimes people would leave with more questions than they came in with," he says with a laugh.
This year's forum — "3.8 Billion Years of Wisdom: Exploring the Genius of Nature" — promises more of the same. Nothing conventional, but an examination of the "many beautiful examples of life forms accessing information that we simply cannot explain, but call 'instinct,'" as the promo material says. It runs May 1-2 on the Promega campus.
This is the fifth year the forum has burrowed into consciousness. "There are different points of view of consciousness in nature and taking it a step further — not just of consciousness, but also of intelligence. Does the very embodiment of matter, particularly as expressed in life forms, exhibit a form of intelligence that doesn't quite fit the human definition of IQ?" Linton asks.
"Nature seems to have evolved with the ability to combine intricate, amazing complexity in ways that are astounding and that we don't understand," he adds. The great controversy, he continues, is whether evolution is a blind, random process that sometimes produces advantageous mutations. "Or is there something else happening that is not totally blind randomness?"
This question certainly stopped me in my tracks.
Linton points to the statistical unlikelihood of a light-sensitive organ like the eye evolving in nature eight or nine times from completely different origins. "The fact is, it seems like nature wants to enhance its ability to take in sensory information, and then do things with that information. Some people say that the nature of the universe is trying to find a way to ask the questions: Who are we? What's out there? Why do we exist?
"In a way, when we ask those questions, it's nature [expressing] itself, because we are a product of this natural process. That's pretty amazing for nature to have brought in this element of consciousness."
The forum runs May 1-2 on the Promega campus in Fitchburg. To read more, please go here.
Categories: Divertissement, Education, Tech, TheDailyPage.com/Isthmus
Tags: Bill Linton, Biotechnology, Information Technology, International Bioethics Forum, Promega
Now For Something Entirely Different
If I lived an alternative life in journalism, garden writer could be it. This piece in Madison Magazine concerns one of my favorite flowers. It begins:
I have a penchant for advocating lost causes: Miles Davis's electric period, Lyndon Johnson's presidency, horseradish Havarti cheese. But none more disdained than ditch lilies.
These are the orange daylilies—formally called Hemerocallis fulva but also known as tiger, roadside or tawny lilies—that you see happily blooming in mid-July in just about every yard in Madison's older neighborhoods. The experts snicker.
Oh, you might as well wear white shoes after Labor Day or extol the virtues of two-buck chuck wine as grow ditch lilies. They are the Rodney Dangerfield of landscaping: They get no respect. You can't buy them at garden centers. Glorious Olbrich Gardens doesn't even display them. Worse, they're branded with the plague label.
Invasive species!
To read more, please go here:
Categories: Divertissement, Madison Magazine
Tags: Ditch lilies, Hemerocallis fulva, Jung's, Olbrich Gardens, Tiger lilies
I'll Have What She's Having
Here's something different–a story about the most delicious peach in the world. It begins:
When approaching a ripe donut peach, one must temper lust with mindful restraint. First, assume a wide stance, slightly flexing your knees to maintain balance. Then gently grasp the saucer-shaped fruit with your thumb and middle finger, careful not to squeeze too tightly. Thrust your head forward, eyes closed, chin out, mouth open and prepare to swoon.
That first bite will release a wave of sugary goodness slobbering down your chin and, you hope, not on your Tommy Bahama camp shirt or Eileen Fisher cami. Spritzing is always a danger. Envious friends and family who have leaned in to take a close look may get a sudden jet of peach juice to the face.
They too may fall to the ground, writhing in pleasure.
"It's a fruit you would have expected in the Garden of Eden," says a close friend who shall remain nameless to protect her professional reputation. "It's fleshy and practically obscene with sticky sweet, dripping juices. If I were Eve, I would have tempted Adam with a donut peach."
Psst. I can get you some….
Tempted? To read more, go here. Among other things, you'll learn that, according to Daoist mythology, a single bite of a donut peach can bring immortality.
Categories: Divertissement, Madison Magazine, Organic Farming/Local Food
This Madison Magazine piece was fun to write–an encomium to Restaurant Magnus mixed with New Urbanist reflections on the making of great urban spaces. The story begins:
Apparently I've lived too long. I've outlasted another bar, and at my age that's trouble. Like true love, a good bar calls for a lifelong relationship. But Restaurant Magnus, after a thirteen-year run on East Wilson Street, has died and left me befuddled like some widowed geezer. Me, date again?The always comfortable Harmony covers my east-side needs. But I'm in search of a new downtown hangout. Will it be Johnny Delmonico's? Capitol Chophouse? Sardine? Genna's? The soon-to-be-open Tempest Oyster Bar? Or Natt Spil? I don't know, I just don't know.
What I do know is this: As a freelance writer I need a Magnus-like place to meet sources. I spend most of the day in sweatpants, torn T-shirts and bunny slippers staring at a computer screen and working the phone in my daughter's old bedroom (my office!).
To read more about drinking, hanging out and journalism, please go here.
Something old and different
Since I posted my Madison Magazine story on twists, I should dig out my 2006 story on the best bars in Madison for bourbon and scotch. The piece ran in the Isthmus Dining magazine. For whatever reason, it was never posted at TheDailyPage.com. Here's the story minus the outdated sidebars: Bourbon-Scotch 2006
Ah, yes, I like a well-prepared drink. Here's my Madison Magazine piece on the art of the twist, including some cocktail history from the marvelous mixology chronicler David Wondrich.
Reading / Listening List
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If you're into film, this interview is essential listening: youtube.com/watch?v=bDiK6m… 1 week ago
Spotted in Paris: My favorite political poster. https://t.co/LNYb3M7lqs 3 weeks ago
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This fresh, healthy, and delicious vegetable pasta dish from Chef Rocco DiSpirito showcases his Italian cooking roots. He says, "Italians are champions of simple, classically delicious ways of using fresh tomatoes. And they should be; they've been cultivating them for hundreds of years. One of the many basic ways they prepare garden-fresh tomatoes is in a pomodoro sauce made with basil and garlic tossed with pasta (or in this case, spiralized vegetables)." Recipe is Reprinted with permission from Rocco's Healthy + Delicious by Harper Collins Publishers.
Cut the ends off of the zucchini, squash, and carrots. Using the instructions with your spiralizer, cut the vegetables into long angel hair-shaped pieces.
In a bowl, mix the squash and zucchini noodles together and lightly salt them. Set aside to drain.
Place the carrots on a microwave-safe plate and cover with plastic wrap. Microwave until softened, about 4 minutes. You will need to do this in two batches.
To make the pomodoro sauce: Heat the olive oil in a large sauté pan over medium heat. Add the garlic and cook until soft. Add the chile flakes and half of the basil and cook until fragrant, about 3 minutes. Add the tomatoes and cook until softened and beginning to fall apart, about 10 minutes.
Drain the liquid from the squash and zucchini. Place in a large bowl. Add the carrots and mix together.
Place a portion of the pasta on a microwave-safe plate and heat for 30 seconds to warm through. Repeat for all the portions. Top with the pomodoro sauce, the remaining basil, and the Parmesan.


Can anyone tell me how to correct this .
Oh dear I'm useless at computer stuff. It's a pity we don't live around the corner I could send one of the "men" around.
Instead of emailing leave a comment asking for their email addy, you do not have to publish all comments you can deleate them.You can leave your email and ask for it not to be published too.


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Home Academics Degree Programs Museum Studies
The Museum Studies Program at IAIA is one of but a few undergraduate museum studies programs in the USA. IAIA offers a Bachelor of Fine Arts degree, an Associate of Fine Arts degree, and a minor in Museum Studies. The department also offers a 30-credit certificate to those who wish to pursue careers in a museum or related institution.
Bachelors of Fine Arts in Museum Studies
The first two semesters of the program focus on a core curriculum of six essential courses designed to introduce students to all aspects of museum studies. These range from the theoretical and legal issues to the practical aspects of safely handling cultural objects, cataloging collections, and working with Native communities. Later semesters provide a wide array of upper division courses, allowing students to customize their Museum Studies degree to fit their interests and career goals.
Experiential learning is incorporated into classroom assignments, including the installation of exhibits in the on-campus Balzer Contemporary Edge Gallery. Ideally, students complete two internships during their last two years in the degree program. Through our intensive internship program, students have the unique opportunity to apply the knowledge gained in the classroom to actual museum application at some of the leading institutions of art in America. These include:
Museum of Indian Arts and Culture in Santa Fe
School of Advanced Research in Santa Fe
IAIA's Museum of Contemporary Native Arts
The Metropolitan Museum of Art in New York City
The National Museum of American Indian Art in Washington DC
Additionally, Museum Studies majors are eligible to apply for the Journey Home Application, which offers ten paid internships during the summers of 2015–2017.
BFA Learning Outcomes
Demonstrate skills and techniques of museum exhibit design and installation
Contextualize components of museum collections as they pertain to its cultural meaning
Identify and synthesize indigenous protocols, customs and sensitivities in museum settings
Analyze and critique the roles and responsibilities of the various museum and cultural center professions
Employ new and applicable technologies within the museum field
Construct new models of museum representation and interpretation
Associate of Fine Arts in Museum Studies
The AFA in Museum Studies is a pre-professional degree program providing the student with the first two years of a four-year Museum Studies Bachelor of Fine Arts course of study. Upon completion, the student will be prepared to seek entry an level Museum studies position or matriculate into the baccalaureate program at IAIA or another school of choice.
AFA Learning Outcomes
Articulate and differentiate the various roles and responsibilities of museum and cultural center professionals.
Demonstrate fundamental knowledge of Museum Curation, Collections Management and Repatriation history.
Demonstrate elementary skills and techniques in Exhibition design and installation.
Recognize and place art within a historical, contemporary and cultural context.
Museum Studies Certificate available Online and In-person
The certificate program introduces students to all aspects of museum studies from theoretical perspectives to practical applications. Courses are arranged with weekly video demonstrations, readings, and original research assignments. In addition to learning the details of museum operations, students also learn about the ethical and legal considerations involved in collecting, storing, and exhibiting Native American cultural objects. The program is designed for working professionals unable to travel to campus. The same classes are also offered in-person as classes available on campus.
Certificate Learning Outcomes
Recognize curatorial best practices
Demonstrate proficiency in collection management technique
Evaluate indigenous concerns in cultural heritage institutions
'Museum Studies go to the heart, mind, and eye. Each culture defines for itself what is the ultimate form of self-expression…."
Rick Hill
Former Museum Director of the IAIA Museum of Contemporary Native Arts, Creativity is Our Tradition, 1992
Careers and Educational Pathways
Students are qualified for a wide range of positions in the museum profession upon graduating from the Museum Studies program.
Graduates can work as collections managers, curators, education managers, museum directors, repatriation officers and in a number of other positions within the field of museology. They may also pursue graduate study in art history or related fields.
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The essence of renewing energy and inspiration to attend to all facets of Life creatively and with equal enthusiasm. To be dynamic. To resolve the internal conflict between desire and duties, personal expression and responsibilities. To work on Life as a whole rather than separating it into antagonistic pieces.
Any road is a very hard road to walk when we are in two minds about where we are going. So many aspects of our being can be calling out for desires to be fulfilled in different ways. To integrate ourselves as a whole all desires can be channelled into one major direction. This can be done without causing damage to ourselves or others when the direction is a spiritual one, because spiritual means all aspects are developed in harmony. This process brings us the boon of always looking forward to Life's experiences and having a mind full of vigour and optimism.
For those experiencing lethargy, listlessness and inability to get enthusiastic about their Life.
For a problem with getting up in the morning, or sleeping too often during the day.
For adolescent and midlife dilemmas of rebellion or frustration about duties and family ties.
For those who cannot see how they can truly enjoy their Life and maintain their job, family or other foundations of their Life. They may resign themselves pessimistically or become hedonistic, because they can't see how they can attend to both directions simultaneously.
For those who fluctuate between being responsible and then totally neglecting their responsibilities.
For those suffering from burn out.
Large Intestine acu-point on the ear.
Can't care about things, drifting along.
Eye diseases, eye strain, problems focussing.
resolves the conflict in the mind that our creative desires and wishes for fulfilment always have to be at odds with our relationships and other commitments. It brings the realisation that one must use breadth of vision, creativity and good energy to make sure all parts of life are developing equally. The bringing together of the split energy-mind directions brings about a renewed zest for Life and enthusiasm to work things out holistically.
This entry was posted in Flower Essences Index and tagged desire, divided, enthusiasm, frustrated, holistic, lethargic, rebellious, resolve, responsible, uninspired.


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Click to copyhttps://apnews.com/40734b0483374f5093b627c2060010da
Dozens of militants evacuated from southern Syria
In this photo released on Friday, Dec. 29, 2017 by the Syrian official news agency SANA, Syrian government forces stand on their checkpoint as busses, background, wait to evacuate Syrian militants and their families from Beit Jin village, in the southern province of Daraa, Syria. Dozens of Syrian militants and their families have left aboard buses an area where they have been besieged by government forces near the Israeli-occupied Golan Heights part of a deal to clear yet another district from insurgents. (SANA via AP)
BEIRUT (AP) — Dozens of Syrian militants and their families departed aboard buses from an area besieged by government forces near the Israeli-occupied Golan Heights early Saturday, part of a deal to clear yet another district of insurgents.
The evacuations came as government-controlled media said two mass graves were discovered in the northern province of Raqqa where the Islamic State group held sway for more than three years.
The government-controlled Syrian Central Military Media said 153 people, including 106 fighters, left the village of Beit Jin early Saturday toward the southern province of Daraa.
The Ibaa news agency of the al-Qaida-linked Levant Liberation Committee said six buses carrying fighters and their families arrived in rebel-held parts of Daraa province.
On Friday, Syria's state news agency SANA said some 300 al-Qaida-linked militants and their families would be sent to Daraa and the northwestern province of Idlib.
The evacuation allows the government to reassert control over Beit Jin near the Golan Heights that were captured by Israel from Syria during the 1967 Mideast war.
Israel has publicly warned against the accumulation of Iranian and Iranian-backed forces at its border. Iran has arranged for thousands of militiamen from across the region to fight on behalf of Syrian President Bashar Assad's government and has sent top commanders to direct its own Revolutionary Guards in the country as well.
In northern Syria, SANA reported that "dozens of bodies" of civilians and troops killed by IS were discovered in two mass graves in the village of Wawi near the northern city of Raqqa, once the de facto capital of IS.
IS carried out public killings in its once self-declared caliphate, beheading, shooting and stoning perceived offenders to death, as well as drowning them in large pools while locked in metal cages.
SANA said that after residents returned to their village some of them received information about mass graves near the village and once a search began the two graves were discovered.
The agency quoted a local official as saying that work is ongoing to remove more bodies, adding they are trying to identify the dead in order to hand their remains over to their families.
SANA posted several photographs showing the remains being unearthed and placed on sheets.


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I'm considering running a bi-monthly, long-term GURPS campaign here on FG and was wondering what the interest would be.
Character restrictions: The limits of your imagination.
Infinity is a concept in many fields, most predominantly mathematics and physics, that refers to a quantity without bound or end. Infinite possibilities. Infinite realities. Across the Multiverse, every possibility is played out in an infinite number of realities. Life in all it's varieties exists across the worlds without end. An evil from beyond all existences is rising, it's darkness spreading and threatening all of the Multiverse. Few and far between are those that can even sense this rising shadow, fewer still have the power to confront it's sinister plans and machinations. You are, or will become, one of those few. It is up to you to become aware of the growing Darkness, seek out others like yourself, discover the source of the evil and confront It's nihilistic plans before the entire Multiverse is consumed by It's evil.
Play whoever and whatever you want from any setting, genre or source. The plot, simply put, is a diverse group of beings, gathered from across the multiverse is assembled to confront a growing darkness that ultimately threatens all life everywhere. Inspired by American Gods, His Dark Materials, LOTR, SLA Industries and incorporating themes and elements from The Cthulhu Mythos, The Malazan Book of the Fallen, Starwars, Warhammer 40,000, Startrek, Marvel Superheroes and everything in between. GURPS : Multiverse is an epic, cinematic,reality spanning adventure, where the characters learn of and ultimately confront a dark, ancient threat to all life in every reality. This game will be roleplaying-centric with an emphasis on character development. you can play whoever and whatever you want. With that in mind, let me say that character concept and development is infinitely more important then power level and point total.
When creating a character, point total is tertiary, with character concept being the primary importance and character roleplayability a close second. Create the character you most want to play, within the boundaries of 850 points in Advantages and up to 150 Disadvantages. I'm not saying go crazy and make a 1000 point mystic warrior that can defeat armies single-handedly, unless that is what you want to play. I will allow ANY character as long as it is well developed, with a rich and detailed backstory including a detailed summary of the world/universe that they come from. If you want to play a character from popular fiction/Television/movies/etc you can and are encouraged to do so. Want to convert your favourite character from a different game system? Go for it.Your world will be incorporated into the over-arcing plot. Don't worry if you make a 200 point character when you could make a 1000 point dragon, the purpose of this game is not power. This game is plot driven. The threat level will be tailored to characters. If you do make a 1000 point character, you will be confronted with foes that are a match for you and placed in situations where all your dragonly might is useless. The 230 point Sherlock Holmes character will be equal to the 1000 point reformed Smaug as roleplaying and thematic development will ultimately be the deciding element. If needed we can always balance out lower powered characters with subtle advantages like Ridiculous Luck or Major Destiny and use the optional rule of spending CP to reroll failures with a stockpile of extra CP.
"Thomas...Please don't run. I am called Wednesday. My associate is named Hecate."
As Wednesday gestures toward the Stunning woman, she alights gracefully on a nearby air vent, sitting cross-legged. Her shimmering black hair falls like a waterfall down her pale slender shoulders, luminescent icy blue, almost mirror like eyes stare out of an angelically beautiful face. Her skin was like smooth milk,silky and flawless.
"Thomas. I know everything about you. About your family... And... I need your help. Will you listen to my proposal?"
He smirked, "...IF you tell me how you lost your eye."
"It's a deal Thomas. Though you may find what I have to say unbelievable. But listen.. and then let me show you the truth of my words... Let me tell you the story of how I lost my eye... for uncountable years I have been travelling the multiverse, slipping from realm to realm by any of the myriad means at my disposal. The easiest way is a gigantic mystical tree that exists in my realm, a tree whose very roots and branches stretch far out, reaching to different dimensions. This tree, named Yggdrasill in my native tongue, will become important later on in my story."
"As the years fled by, melting into centuries and I moved from world to world, I began to notice disturbing trends forming throughout the multiverse. Dark cults began to manifest, dedicated to destruction, fanatics rose to power across the multiverse, misery spread like a disease... Whole worlds, entire galaxies were consumed by nihilistic warfare. I turned my mind towards solving this dark riddle and slowly became aware of sinister forces at work, moving across the realms,influencing the course of fate on a uncountable worlds. Amassing power, forming great and terrible armies... Worse then that... they were looking for something. To confront them directly would be utter folly. I was barely aware of their existence, let alone the extent of their power or numbers."
"Hecate can attest to the savagery of but one small part of the forces aligned against us. The K'Chain Che'Malle are a reptilian race using both magic and technology.Their cold, merciless reason has wiped numerous peace-loving races from existence. To confront them directly would require me to raise an army, it would take years and even then the outcome of that war would be uncertain. Even if I was victorious, it would be at a terrible cost and would leave me no closer to knowing the true face of this threat."
"To find out what darkness threatened all existence... I undertook a terrible ritual. The mighty Yggdrasill reaches throughout the multiverse and as such has a power and permanency that allows for truly powerful magic to be enacted within it bows. I performed a great ritual spell wherein I removed my own eye with a dagger and had my allies crucify me to the great tree. For a year and a day I suffered, nailed to Yggdrasill. Through agony I gained enlightenment.When my allies returned and removed the cold iron nails from my hands and feet I knew what we faced and what I must do. In the delirium of agony, I saw the lives of the group I must assemble. I saw each of them on their various worlds,in their various realms of existence..."
"I sat as a disembodied ghost and watched as they were born or created, watched them grow or be assembled... I walked every step of their lives... I know your anger and pain Thomas, for I was there when you saw your family slain, I was there when you enacted your terrible vengeance upon their killers... In loosing my eye I gained sight. I have seen your life, every day from the time of your birth up until when you landed upon this rooftop. I have seen this meeting. I am not your enemy Thomas. I am your alley. I have walked with you your whole life... You mistrust me as from your perception we have never met before and my tale is wondrous and hard to believe. For me it is as if we are reunited, old, dear friends separated by oceans of time... I have missed you Thomas... I feel as if you are my own son."
"That is how I lost my eye, it is also why you have to help me. I need your dedication, I need the strength of your arm and the keenness of your blades in this fight against the growing darkness."
Consider me an interested party, but scheduling will be important.
I'd be interested, but the scheduling would be key.
Is there an expected/suggested experience level for the players? I'm a long-time RPG player/GM, but a relative newcomer to both GURPS and FG, though I'm a fan of both.
Is this on the calendar?
Not yet as I am still gauging interest. I'm flexible with my schedule and would like to play every other week as I run another game here on FG.
There is nothing set in stone other then the 850 ADV/150 DIS point cap on points for creating a character. But, as I said in my game concept intro, this game is not about power. If you were to make Superman, I promise you, everyone we encountered would be packing Kryptonite based laser weaponry.
Assuming a bi-weekly game, what day/time would be best?
Hi mariic you might be interested in one or both of Bane Roots one shot sessions at FG Con.
Sundays are out for me and it looks like my weekends in general will be occupied. Friday nights are workable.
I am not sure what the status of the campaign in this thread is, but i wanted to add myself as an interested party. To give you a quick background. I am an experienced pnp rpg'er who played mostly Gurps, but also AD&D, Torg, Call of Cuthullu, Rolemaster etc. Owing to life I had to stop for a long time (kind of around the time when Steve Jackson made the switch to GURPS 4e) and am now looking forward to get back into the game(s). I am not conversant with FG, but I am a quick study and usually pick up software quickly.
PM me with any questions you might have!
I am free any evening (9:00 PM EST), but weekdays is currently best, although that might change in the future.
Any news on this campaign?
Game postponed indefinitely due to real life complications and lack of player interest.
Subbed in case you ever decide to resurrect this idea.
My work schedule is shift work, rotating every two weeks. That means that if we were to play bi-monthly, we could play every two weeks on the same day. If we wanted a weekly game (ideally) it would mean switching days every week. For example, play on Tuesday evening one week, Wednesday evening the next. Then repeat. It has been my experience on FG that finding players isn't difficult. The difficulty is finding a time when everyone is available. The upside of shiftwork is that I know my availability for the entire year, so if we could agree on a specific game schedule, I'd be able to commit to it long term.
Is a Tuesday/Wednesday alternating weekly game feasible for people? Or should we go with a bi-monthly game?
Alternating days would work for me, as long as it was after 8 pm Eastern or so.
At the moment, bi-weekly would work best for me. But that might change in the near future. Then I would be up for an alternate schedule (EST 8 pm works fine for me).
I saw this thread and thought "interesting artwork, DAY YUM!" Then I saw the points available and panicked thinking "I always try to keep the lid on character builds around 150 to 250 points because my players (face to face that is) tend to go hog wild with all the points beyond a "normal" human being style character.
I finally set up an Obsidian Portal account to try to create my very own CHROME NIGHTS using GURPS and R. Talsorian's NIGHT CITY, but I'm going to have to do a LOT of prep work before I start a major casting call! As it is, I'm grabbing a guy from SJGames Forums to test out the idea of using "cyberdeck programs" as spells in GURPS CHARACTER ASSISTANT. This way, I can set it up for players to do net runs using the original GURPS CYBERPUNK rules and see if it is feasible for use with FB2 or not. The use of Odin and the Goddess in the opening phase had me thinking "Interesting".
Did this ever get off the ground? Haven't played in a long time, but this sounds interesting.
Sadly, not as far as I know.
Game is still a work in progress, just put on hold temporarily and then postponed. I am back in the design/recruitment phase. There are two concerns I have when starting up this game.
1) The point total. Having recently run a 1200 point GURPS supers game, I have come to realise that the GURP system breaks down if too many points are used in character generation. To avoid that, perhaps a more modest, 450 CP with up to 150 DIS character creation would be more prudent...Alternately we could just have caps of Stats and Skill maximums.
2) Scheduling. While I would prefer a bi-weekly game, I still work an alternating schedule shift work. Is a Tuesday/Wednesday alternating weekly game feasible for people? Or should we go with a bi-monthly game played at the same day/time?
Game postponed indefinitely due to lack of player interest/lack of GM free time.
The game of my dreams and I'm a year late and a dollar short... history of my life.
If you ever plan to get this off the ground again, I'm all in. I love kitchen sink settings and high power games.


text:
Q: Deriving the approximate moments of normal ratio distribution Let $W$ be the ratio of independent normal random variables
\begin{equation}
W=\frac{\mu_{1}+\sigma_{1}Z}{\mu_{2}+\sigma_{2}Z}=\frac{X_{1}}{X_{2}}
\end{equation}
where, $Z\sim\mathcal{N}(0,1)$. Given that $\mathrm{Pr}(X_{2}>0)=1$, the cumulative distribution of $W$, $F(w)$, can be expressed as
\begin{equation}
F(w) = \Phi\left(\frac{\mu_{2}w-\mu_{1}}{\sigma_{1}\sigma_{2}\sqrt{\frac{w^2}{\sigma_{1}^{2}}+\frac{1}{\sigma_{2}^{2}}}}\right)
\end{equation}
where, $\Phi(x):=\int_{-\infty}^{x}\phi(t)\, \mathrm{d}t$ is the standard normal cdf, and $\phi(t):=\frac{1}{\sqrt{2\pi}}e^{-t^2/2}$ is the standard normal pdf. For more information on this distribution see "On the ratio of two correlated random variables" by D.V Hinkley JSTOR.org.
Since $X_{2}$ is assumed to have zero density at zero, the moments of the ratio density $f(w)$ exist. I want to find the skewness of $f(w)$ which requires knowing the first three raw moments, i.e. $\mathbf{E}[X]$, $\mathbf{E}[X^2]$, and $\mathbf{E}[X^3]$. To attempt this I first found the density of $W$ by differentiating $F(w)$. Let,
\begin{equation}
a(w)=\frac{\mu_{2}w-\mu_{1}}{\sigma_{1}\sigma_{2}\sqrt{\frac{w^2}{\sigma_{1}^{2}}+\frac{1}{\sigma_{2}^{2}}}}
\end{equation}
Then the density function is
\begin{equation}
f(w)=a^{\prime}(w)\, \phi(a(w))
\end{equation}
The mean, $\mu_{W}$, is then
\begin{equation}
\mu_{W}=\frac{1}{\sqrt{2\pi}}\int_{-\infty}^{\infty}w\,a^{\prime}(w)\, \exp(-a^{2}(w)/2) \ \mathrm{d}w
\end{equation}
Performing integration by parts where
\begin{equation}
\begin{aligned}
&u=w\\
&\mathrm{d}u=\mathrm{d}w\\
&\\
&\mathrm{d}v=a^{\prime}(w)\,\exp(-a^{2}(w)/2) \ \mathrm{d}w\\
&v= \sqrt{\frac{\pi}{2}}\, \mathrm{erf}\left(\frac{a(w)}{\sqrt{2}}\right)
\end{aligned}
\end{equation}
gives,
\begin{equation}
\mu_{W}=\frac{w}{2}\, \mathrm{erf}\left(\frac{a(w)}{\sqrt{2}}\right)\bigg|_{w=-\infty}^{\infty}-\frac{1}{2}\int_{-\infty}^{\infty}\mathrm{erf}\left(\frac{a(w)}{\sqrt{2}}\right) \ \mathrm{d}w
\end{equation}
$\mathrm{d}v$ was integrated here. The $uv$ term can be evaluated by writing it as
\begin{equation}
\frac{1}{2}\,\lim_{w\to\infty}\left(
w\, \mathrm{erf}\left(\frac{a(w)}{\sqrt{2}}\right)
+
w\, \mathrm{erf}\left(\frac{a(-w)}{\sqrt{2}}\right)
\right)
=
-2\mu_{1}\,\phi\left(\frac{\mu_{2}}{\sigma_{2}}\right)
\end{equation}
This result can be found here.
This gets me to
\begin{equation}
\mu_{W}=-2\mu_{1}\,\phi\left(\frac{\mu_{2}}{\sigma_{2}}\right)
-\frac{1}{2}\int_{-\infty}^{\infty}\mathrm{erf}\left(\frac{a(w)}{\sqrt{2}}\right) \ \mathrm{d}w
\end{equation}
Consider only the remaining integral. Rewriting the $\mathrm{erf}$ using Taylor expansion gives
\begin{equation}
{\frac{2}{\sqrt{\pi}}}\sum _{n=0}^{\infty}{\frac{(-1)^{n}}{n\,(2n+1)}}
\int_{-\infty}^{\infty}
\left(\frac{\mu_{2}w-\mu_{1}}{\sqrt{2}\,\sigma_{1}\sigma_{2}\sqrt{\frac{w^2}{\sigma_{1}^{2}}+\frac{1}{\sigma_{2}^{2}}}}
\right)^{2n+1} \ \mathrm{d}w
\end{equation}
I am able to get a solution to the indefinite integral for the above here...it's not of much use.  After evaluating the antiderivative at the limits of integration might yield something more useful but I was not able to get that far. Does anyone see a way to the solution from here?

redpajama_set_name: RedPajamaStackExchange


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With conflicting demands on staff and time, video services departments are often unable to effectively prioritize what should be done first, what's most important, or how content should be produced for multimedia use or distribution on a variety of channels. In many instances, without a strategy for prioritizing production, or an organizing principle, what's left is an ad hoc approach to producing what they are asked to do. This may enable them to keep churning out work, but it may not be an effective use of staff time or resources, or more importantly, advance the organization with its most important audiences. It often also results in content that has a short shelf life and cannot be optimized for rebroadcast or aggregated along with other content in any kind of coherent fashion for thematic programming and viewing.
An additional factor that can come into play is the chain of command for video services. The politics of cooperation or competition between vice presidents in an organization can have a profound impact on what the responsibilities of the department is and which parts are best serviced, versus which has the greatest strategic value. Moving video services from one reporting structure or budget center to another and the way in which it reports on its metrics can significantly impact effectiveness.
One client example with which Integrated Media Strategies worked was a community college, and more about the project is at News. The nature of higher education communications aside, the issues with which they are wrestling have many commonalities for a broad number of organizations using video for training, marketing, best practices, client retention, or other uses.
At least every five years, and more frequently at commercial operations, organizations should comprehensively review the operational output, along with the budgetary implications of staff, equipment, and space that are required for effective video production against the organization's strategic communications plan in terms of cost/minute/viewer.
This review should be comprehensive, taking into account who is using the video products, who might be needing digital video products for support, marketing, best practices or internal communications, and whether the organization has the capacity to meet these needs. The department might be better served being in a different location, funded from a different organizational line item, require more equipment or staff - or everything may be working well.
Often there are more effective ways of doing things that directly impact reach and with technology changing at a rapid pace - both production tech as well as methods of distribution - regular reviews are simply good sense.
The principal at Integrated Media Strategies has started both national and local digital newsrooms; consulted to national morning TV in Germany; and led statewide community college initiatives, including federally-funded programs. Contact us to discuss how we can help your organization's video services department operate more effectively.


text:
Human Bio-Diversity (HBD)
Physical Anthropology
Europoid
Nordid
European Nordish Regions: Kociewie (Poland)
Thread: European Nordish Regions: Kociewie (Poland)
Monday, October 13th, 2003 #1
Thursday, November 20th, 2008 @ 09:58 PM
The region of Kociewie constitutes the east part of Pomorze Lake District and is situated in the basin of two rivers flowing into the Vistula River; these are the Wierzyca River and the Wda River, called also the Black Water. The east border of the area of Kociewie constitutes the one-hundred-kilometre long part of the Vistula River, from the town of Świecie to the village of Koźliny (north of Tczew). At the north and the west, the borderline follows roughly the line of the villages: Pszczółki - Trąbki Wielkie - Nowy Wiec - Wysin - Nowe Polaszki - Bartoszylas - Konarzyna - Czarna Woda - Szlachta - Linówek; at the south it is more or less the line of: Łążek - Drzycim - Gruczno (south from Świecie).
The name of Kociewie was probably in use as long ago as late middle ages, though in a written text it appears for the first time much later in the year 1807. The word "Gociewie" was used then which, in the opinion of the historians, suggest its origin from the Goths, present once here. Other hypothesis is that the source of the name is the old-polish word "kociwie", which meant as much as "godforsaken land". Kociewie encompasses the area of roughly 3,000 sq. km, 80% of which is situated in the Pomorskie province, while the remainder in the northern part of the Kujawsko-Pomorskie Province. The capitol of Kociewie is the town of Starogard Gdański. If to believe the researchers, who claim that the ethnic group of Kociewiacy (the people of Kociewie) appeared in the 12th century due to blending of the local people of Pomorze with the influx settlers from the areas of Chełm and Kujawy, one could risk the statement, that Kociewie is about 800 years old.
The main part of Kociewie belongs to the Pomorskie province. The rest belongs to the Kujawsko-Pomorskie province, and so it will probably remain, as the business and social interests are stronger than cultural issues shame, as in the once-proposed bigger province of Pomorze Nadwiślańskie we would have been one again, as we were 800 years ago, at the time of the reign of prince Grzymisław, who ruled, inter alia, the areas of Starogard, Świecie, and Lubiszyn (near Tczew). The cultural life of Kociewie was concentrated around the three main centres: Tczew at the north, Starogard as the capitol of the area, and Świecie at the south, even though the 800-hundred-years old Skarszewya and the charmingly situated Nowe also found their places in the history of the region. For the last few years, the knight's town of Gniew and the village of Czarna Woda are becoming more known. When it comes to the town of Pelplin well, everybody knows about its magnificent cathedral, and about the Diocese Museum, which encompasses, among other things, the only one in Poland specimen of the Bible of Guttenberg.
Once we invoke also the town of Skórcz we will realise how urbanised is the region, from which the Virgin Mary of Piaseczno watches over the entire Pomorze. We find comfort in the image of Virgin Mary of Lubiszyn, the legendary picture of the Virgin Mary of Lubiszyn also tights us to Gdansk just like the Vistula, which has its museum in Tczew.
The charm of the region's landscape varied relief (Starogardzkie Lake District, Świecka Plain, also Góry Diabelskie Devil Hills), fine lakes and forests (part of Bory Tucholskie The Tuchola Forests) evoked the decision to establish two landscape preservation parks: the Wda Landscape Park and the Vistula Landscape Park.
Kociewiacy a mixed ethnic group, which used to be divided into three sub-groups (Górale, Polusowie, Lasacy), inhabits this beautiful land. In the past centuries Feteracy and Olendrzy living in the Vistula Valley were the ethnically alien element.
There is a dispute among the historians, which concerns (simplifying) the subject, whether there was an ancient settlement of Kujawy and Pomorze in Kociewie, or if the influence of central Poland came only later to the area belonging strictly to Pomorze. Some names of settlements (e.g. Starogard, Warlubie, Wiąg), being a kind of linguistic fossil, tied Kociewie to the region of Kaszuby (it's worth to look at the dictionaries of Kaszuby and Kociewie by B. Sychta). The relatively simple dialect in turn, which resembles general Polish, is the main reason of the expansion of the Kociewie dialect onto southern Kaszuby, Bory Tucholskie, and the area of Malbork.
According to the saying "the language is the man", the borders of Kociewie are drawn by its tongue, which was spotted early by the founder of Polish dialectology, Kazimierz Nitsch. He arrived at the beginning of the 20th century to Kociewie and found it surprising, how simple is the tongue along the Vistula. He divided the area mainly due to the pronunciation of nasal vowels into Kociewie: northern, middle, and southern, at the same time considering the Proper Kociewie as the area between Pelplin and Nowe. In many studies we can find the opposition the proper Kociewie, plus its extension at the large part of the area of Świecie. The Kociewie dialect, its culture and history deserve separate articles in the periodical of "Pomerania", which portrays the details of the Pomorze puzzle. The Land of Kociewie Association has been watching for years not to let the local culture weaken or disappear. The Kociewian branches of Zrzeszenie Kaszubsko-Pomorskie (Kaszuby & Pomorze Association) appeared during the last decade - from Bukowiec Pomorski, through Świecie, Piaseczno, Pelplin until Zblewo etc. Kociewiacy themselves should learn Kociewie some interesting ideas in this area are being brought into life by Kociewskie Towarzystwo Oświatowe (Kociewian Educational Society), which emerged in Tczew and seems likely to have its field branches soon, as one is never too old to learn…
Kociewie: 40-45% pure blonds and blue eyes, 7,5-9,9% brunets minority
European Nordish Regions – Tallin/Estonia
Tuesday, October 28th, 2003 #3
European Nordish Regions – Villnius/Lithuania
European Nordish Regions – Moscov-Obninsk/Russia
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It is 1961 and Rudolf Nureyev (Oleg Ivenko), not yet the imperious figure of legend, is a member of the world-renowned Kirov Ballet Company, travelling for the first time outside the Soviet Union. Once arriving in Paris Nureyev falls in love with the city, but the KGB officers who watch his every move become increasingly suspicious of his behaviour and his friendship with the young Parisienne Clara Saint. When they finally confront Nureyev with a shocking demand, he is forced to make a heart-breaking decision, one that may change the course of his life forever and put his family and friends in terrible danger. Directed by Ralph Fiennes, The White Crow tells the true story of an incredible journey by a unique artist who transformed the world of ballet forever.


This timeline provides copies of official documents not published before about the U.S. pressures in the Dominican Republic during the congressional debates that led to the adoption of the TRIPS-implementing legislation Law 20-00. These documents were obtained via FOIA requests. A previous and more detailed timeline about U.S. pressures in the Dominican Republic is available here.
1997. May 9. The U.S. Embassy in Santo Domingo reports to Washington the outcome of an USAID-funded event titled "Arbitration, intellectual property, and judicial ethics". The speakers were Richard C. Wilder, Attorney Advisor for the USPTO; Leslie Ackerman, Assistant Vice-President of the International Division of PhRMA; and Jay Monahan, working with Disney and the Motion Picture Association. There were "heated exchanges" during a meeting between Ackerman and representatives from the association of generic companies, INFADOMI.
1997. July 15. USPTO Attorney Advisor Richard C. Wilder sends an analysis of the Dominican patent bill to the U.S. Embassy in Santo Domingo. Wilder highlights a long list of issues he considered inconsistent with the WTO, including article 36 which provided a time limit of 180 days in which voluntary agreements must be reached before granting a compulsory license.
1997. August 1. The U.S. Department of State was "concerned" with reports suggesting that the Dominican government had hired a consultant, whose name was redacted, "associated with the Argentine pirate pharmaceutical industry" to review the USPTO comments on the patent bill.
1997. August 29. The U.S. Embassy in Santo Domingo updates Washington on the discussions around the proposed patent bill. This cable acknowledges the involvement of Argentinian academic Carlos Correa as a consultant for the Dominican government.
1997. August 29. The U.S. Embassy in Santo Domingo states there is a need to "keep the flame alive" and called for "a visit of someone competent to discuss the role of patent protection in enhancing development, TRIPS requirements, and potential sanctions for those WTO members who flout the TRIPS agreement".
1998. March 13. The U.S. Embassy in Santo Domingo reports to Washington that Dominican generic companies "seems to have significant clout at the Secretariat of Industry and Commerce". "The eloquence" of Ho-Chi Vega, a member of INFADOMI, is singled out.
1998. October 23. The U.S. Embassy in Santo Domingo reports to Washington that a health bill introduced in the Dominican Chamber of Deputies proposed a provision requiring the prior consent of health authorities before granting a pharmaceutical patent. Local attorney Mary Fernández Rodríguez gave this information to the U.S. Embassy in Santo Domingo.
1998. October 23. The U.S. Embassy in Santo Domingo reports to Washington, in detail, a list of ongoing legal actions triggered by "the good guys".
1999. March 17. The U.S. Embassy in Santo Domingo reports to Washington, and calls for WIPO's involvement suggesting that WIPO is "well respected here and a few insistent words from them would help enormously to create an understanding that something has gone wrong".
1999. July 23. The U.S. Embassy in Santo Domingo reports to Washington regarding a meeting between an U.S. official with a Dominican counterpart. The first issue raised was the proposal filed by the Dominican Republic at the WTO jointly with Cuba, Egypt, and Honduras, requesting an extension of the transition periods to implement the TRIPS agreement. The Dominican Foreign Minister "immediately issued a statement to the press repudiating the WTO action".
1999. September 14. The U.S. Embassy in Santo Domingo took "full advantage" of a USAID-funded visit of John Marshall Law School professor Doris Long "to reinforce the message that full and timely implementation of TRIPS is in the best interests of the DR". The issues Doris Long addressed with "government officials, industry representatives, and others" included patentable subject matter and the regime for compulsory licenses.
1999. November 19. Acting U.S. Ambassador to the Dominican Republic Linda E. Watt met with three Dominican legislators, including majority leader at the Chamber of Deputies Rafaela Albuquerque, to discuss the "shortcomings" of the patent bill that was passed in the Senate. Ambassador Watt told them that they could "either support the interests of a small group of IPR pirates, or support the interests of the Free Trade Zone exporters who could be hurt by trade sanctions if adequate IPR legislation is not passed and implemented".
1999. November 22. The U.S. Embassy in Santo Domingo provides a full account of the USAID-funded visits of John Marshall Law School professor Doris Long, sent to "assists the D.R. in ensuring that their IPR legislation is WTO-compliant". Doris Long went to the country in January and September of 1999, and was invited again to go in December of that same year.
1999. December 10. The U.S. Embassy in Santo Domingo describes the third visit of professor Doris Long to the Dominican Republic. The first issue she addressed was that compulsory licenses were "too easy to obtain", as drafted in the proposed patent bill.
2000. January 7. The U.S. Ambassador in Santo Domingo met with ten senators, led by majority leader Ramón Alburquerque, to address several issues – including the implementation of TRIPS. Alburquerque "responded in a somewhat defensive manner" when the Ambassador inquired about the pending patent bill introduced in Congress.
2000. March 16. PhRMA filed a pre-hearing statement and request to appear at a public hearing the USTR was organizing on the eligibility of the Dominican Republic to the General System of Preference (GSP) program. Among other issues, PhRMA highlighted as "deficiencies in the Dominican Republic intellectual property regime" the provisions for compulsory licenses, protection of confidential data, and patent subject matter.
2000. March 23. The U.S., E.U., U.K., France, Germany, Italy, Spain, Japan, and Korea Ambassadors in Santo Domingo met with leaders of the Dominican Congress with "one message: fix the bill". Two of the "better-informed members of the group" explained that the proposed mechanism for granting compulsory license was compatible with TRIPS.
2000. May 8. The new patent law was signed by President Leonel Fernández.
2000. May 12. The USTR holds a hearing on the eligibility of the Dominican Republic to the GSP program. The Dominican government defended the new patent law, insisting that it was TRIPS-compliant. PhRMA called for a review of the GSP eligibility suggesting that if the Dominican patent law was implemented "the negative precedent will harm prospects for effective patent protection in the region and the larger developing world".


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Bits and Pieces 5/26/11
I heard that the CHS class of 59 was planning a big to-do at the beach this fall and I contacted one of the main movers and shakers of that historic class (it was the LAST CHS class!).....Arleen Clark ( Barry Clark's sister).
She emailed me back:
Ocean Drive Resort Myrtle Beach
"I have been the co-chair of all of the Class of 1959 reunions to date and am planning a big to-do at the Ocean Drive Resort in Nov. for my class and we are also including the Class of 1958. We're not getting any younger, might as well. We have about 70 signed up so far and more to come I'm sure. After the wonderful 50th reunion in 2009, I had no interest in planning any more reunions but did promise to do this so I am.
You know, the Class of 1959 was the very last graduating class from "old" Central High School. I guess you would say we were historic. We also had the first integrated class, Gus Robers, who died years ago. He worked for the Postal Service. I knew his sister, Gervais, who was in the first integrated class at Piedmont Jr. High School, was very fond of her.
A very brave family to be sure. I have attended two "everyclass reunions" on the campus of CPCC and they were a lot of fun.
-Arleen"
Arleen and Barry are both living in the same town of Robbinsville, NC...which is located in the beautiful mountains of South Western, NC. Robbinsville is the Graham county seat.
Spring always reminds me of baseball. And I think back to those days in Chapel Hill when Barry and I were hired by the local radio station to broadcast UNC's games.
Ed and Barry broadcasting a UNC baseball game 1955
Barry did the play by play and I did the "color."
He knew the game very well. I hardly knew it at all.
J.B. Clark
Undoubtedly, watching his Dad, broadcast sports events for WBT in the 40's was good "training."
But frankly, Baseball never caught my fancy.
However, I later grew to really..........despise it.
Not that there was anything wrong with the game, but it began interfering with my life.
The baseball season started getting longer and longer....also you never knew when a game was going to end. And those extra inning games in Chapel Hill seemed to always occur on Friday afternoons, when I was anxious to get out of town and on the road to Charlotte for a Friday night date with my girlfriend. It seemed that the pitcher never could adjust his hat enough...and the batters could never stop hitting enough foul balls....and the innings kept piling up.....as my social life was slowly going to .........you know.
It was maddening.
Later, when I came to work in Washington, my station carried the Washington Senators Games......which for years would wipe out my evening radio show an inordinate number of times during the season. Adjusting caps, arguing with the umpire, pitchers digging up dirt with their feet, and spitting.......all of the "non action" on the field, cost me a lost of money.
I suppose the final irony is that my two sons and my 5 grandsons....are all baseball fanatics....so I have to try to get my grandaddy to grandson "bonding" stuff.......in between innings.
Janice Kirby
Speaking of CHS kids who were the offspring of important Charlotte radio personalities, Janice Kirby, daughter of Lee Kirby was in the class of 53. I remember her very well from Mr. Balance's radio class. She was an exceptionally talented voice actress. I've often wondered if she went into that business, or if the fact that broadcasting was very "unfriendly" toward women in front of the mic until sometime in the '80s kept her away from the business.
Lee Kirby
I remember seeing her father riding his bicycle to work during the gas rationing period of WW2.
Derek Knell, son of Jack Knell, WBT's news director was in our class, of course. His brother Donald Knell, was two years ahead of us.....and was an outstanding quarterback for that year's football team.
Kurt Webster
I vaguely remember Kurt Webster's son at Elizabeth school, whose name I've forgotten, but they had moved on from Charlotte before he would have become old enough to join us at CHS. As I recall, Kurt's (the "Night Mayor") departure from WBT was a big mystery at the time. This was before the era of broadcasters willey nilley changing "formats" and talent every other year or so for no good reason. Apparently WBT was on the leading edge of that phenomenon.
David Brinkley
Around that same time, David Brinkley worked in Charlotte for the Associated Press news service and hung around the station (WBT) which was then in the Wilder Building. The story goes that Brinkley wanted to go to work for WBT very badly, but the general manager, Charles Crutchfield told him in no uncertain terms that he didn't have the "voice" for radio.......and he would never be successful in that business.
Brilliant insight like that is why General Managers and CEOs of businesses make so much money. -Ed
A Story for the Ages
Archy and Mehitabel
More LDL Pictures
Buddy Trexler's Mom Passes
"My life is measured in coffee spoons."
Carolyn (Taylor) Powell recuperating nicely
Two Years Ago
LDL 31 a " Boffo" Event !
I don't know nothing 'bout art, but.....
UP DATE Re TIGHAR
LDL Reminder
Spring!... etc
Ellouise to "Bring Gus Home"


SALISBURY – There is a popular religious phrase and song that goes, "show up and show out." Newly-elected Mayor Al Heggins charged students to "show up" during her remarks at Livingstone College's winter commencement held Dec. 15 at Varick Auditorium.
"I decided to show up. I decided to show up for military duty. I decided to show up even in junior and high school when I was on student council. I decided to show up when I went to college. And I want to thank you and everyone in this audience for showing up because you showed up to vote," she said to applause.
Heggins won the most votes in the race for Salisbury City Council in November, becoming the first African-American female elected to council. On Dec. 5, she was elected by the new City Council as mayor, making history again.
Speaking at Livingstone College was among her first speaking engagements since the historic win.
Heggins shared with the Livingstone College audience a deeply personal story of her ancestry, in which she said she had not shared before in such a setting.
Her grandfather, James White, was born in 1882 into a white family in China Grove. His mother was white and his father was black. When White was born, his mother's father sent her away to Pennsylvania and told her not to return until she was sure her child looked white, she said.
The mother lived in Pennsylvania for three years. Upon return, Heggins' grandfather was integrated into his white family and grew up thinking he was white, she said.
When he became an adult, his grandparents told him the truth and that the woman he thought was his aunt was actually his mother, and that his father was African-American.
Heggins said it took her grandfather a few years to accept that fact, and that is how he met her grandmother, who by the way, is a part of the family that Dr. Charles Price married into. Price is the founder of Livingstone College.
Her grandparents would build a life together in a way that was bold an unapologetic. "He had to show up. They had to show up – and show up courageously," she said.
There are many challenges that await their innovative approaches to transformation – approaches they have learned at Livingstone College. How will they transform immigration, tax reform, global warming, food deserts, opioid abuse, homelessness and diminishing public education opportunities?
Heggins was presented with an honorary doctorate degree from Livingstone College – the Doctor of Humane Letters – by Dr. Jimmy R. Jenkins, Sr., Livingstone College president, and Dr. Carolyn Duncan, vice president for Academic Affairs.
"Let it be known that Livingstone did it first," Jenkins said.
Fifty students walked across the stage to receive their degrees in the December graduation program, which started at Livingstone in 2014.


This week's Delta Quadrant species, is the predatory Hirogen, who live for the thrill of the hunt.
The Hirogen had an interesting arc in Voyager, being teased before their first full appearance. The species had a cameo in 4×14 Message in a Bottle before fully debuting in the subsequent Hunters. The species was featured in eight episodes, including the two-part story The Killing Game 4×18 and 19, making them one of Voyager's most persistent foes.
Hirogen hunting packs are widespread, and could conceivably be found in any region of the Delta Quadrant. Given how widespread the ancient Hirogen were, it's also possible several small hunting packs could have made their way to the Alpha or Beta quadrants over the course of several generations. To say nothing of a single Hirogen ship pursuing desperate prey through a wormhole to the far side of the galaxy. The Hirogen might be an interesting guide through a region of space they have designated their "hunting grounds", or an ally in the pursuit of a mutual enemy.
Nice. I'm hoping you have the Voth on tap – one of the Delta Quadrant species with the most reason and opportunity to turn up in Federation space at some point.


The Money for Hits 'Bounty Program' in the NFL: Is this really surprising?
Gregg Williams, Offensive Coordinator for the New Orleans Saints met with NFL investigators March 5th looking into Saints' bounty system (Photo/Sean Gardner Reuters).
The sports world is all atwitter over the news that between 2009-2011 New Orleans Saints players and their Offensive Coordinator Gregg Williams participated in a 'bounty program.' This program rewarded players thousands of dollars to make big hits on their opponents.
Gasp! Excuse me if I don't pass out from shock.
The reason why this story has turned into a big deal is because NFL Commissioner Roger Goodell is all about protecting the NFL brand. It's also about player safety, but Goodell is probably concerned more about the former than the latter.
Seriously, is this story really that scandalous?! What's surprising is that a couple of coaches were not only aware of the bounty program, but apparently gave their blessings to it. Everything else I'm sure is old news to most in the NFL. The NFL has done a decent job in trying to protect its players from vicious hits, but these type of hits have continued and will continue – it's the nature of the game. Players are taught to hit hard; to knock their opponent down – maybe out of the game.
For the NFL all of a sudden to act saddened and dismayed that a bounty program exists is hypocritical. The league will throw around fines and suspensions – to show people that the NFL really cares.
After the bad PR dust has settled, the bounty program will go undercover again and coaches will do a better job of being oblivious to its existence. Of course there will also be legal ramifications, which I'm sure will be kept under the radar as well. The NFL will be back to its multi-billion dollar business as usual.


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Educational Children's Television Network, Akili Kids, Released in Kenya
Global Center for the Development of the Whole Child
With widespread school closures and stay-at-home social distancing, there has never been a greater need for quality children's programming. The Global Center for the Development of the Whole Child is pleased to share the launch of Akili Network's Akili Kids, a free-to-air children's television network in Kenya. Dr. Neil Boothby, the GC-DWC's director, serves as a senior adviser for the project, which aspires to be the most trusted brand in children and family entertainment in Kenya.
"Jeff Schon, CEO, has poured his heart and soul (and his own money) into transforming his dream into a reality. Akili Kids may indeed become as influential in Kenya as Sesame Street is in the United States."
-Dr. Neil Boothby, Director, GC-DWC
Through the provision of both imaginative and educational content, Akili Kids intends to reach nearly 20 million children in Kenya under the age of 14 with programming that features clear learning outcomes. The network hosts well-established children's educational shows as well as original and locally-developed content. Learn more about this exciting project here!
The Intersection of Haitian Storytelling, Literacy, and SEL
GC-DWC Receives Award to Address Gaps in WCD
Read Haiti partners featured on USAID's Medium
Sign up for updates from the Global Center for the Development of the Whole Child


Pet Munchies Chicken & Cheese : Wolfit. The Pet Shop in Tunbridge Wells and Pet Shop in Tonbridge.
Pet Munchies Chicken & Cheese Treats are premium gourmet treats made from the finest quality chicken breast meat and cheese.
Pet Munchies Treats are completely free from artificial additives, preservatives, flavours or colours.


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The Evolution of Terravita: "Blurring Genre Lines" with Forward Thinking Bass Music
"That's the beauty of music. It's the great escape through feeling the emotions put forth by the beats!"
For many veterans in the scene Terravita is a household name. They have been tearing up dancefloors since the early 2000s with a focus on gritty and raw bass music. Many may recognize their sound as Dubstep, but over the years the due have come to defy genre classifications, never being pigeonholed to one style or sound. Now they're set to embark on the next chapter, and the evolution of their sound is proving to be a fresh interpretation that electronic music desperately needs.
We took the time to sit down with Chris, who is one half of Terravita, in order to discuss their new direction and further understand the vision behind their music. Chris assures us they haven't really changed much, they just know what their fans want and are more focused than ever to give it to them.
I understand you are evolving your sound. What's influencing your evolution and how do you think your sound has changed?
Our music is still bass music, so it's not like we did a 180 and started making techno or deep house. Our evolution within the bass music realm is influenced by what we personally like and are inspired to make. Lately we've really enjoyed blurring genre lines, and using elements of both dubstep and trap, along with interesting melodic elements. We want to do something forward thinking, original, and different. Our sound is also influenced by our fans. If the people that come to see us play go crazy for a certain style of one of our new tunes, we are more inspired to go down the path of the music that our fans at our shows are reacting to. Our sound now has more melodic elements and more vocals, both from Jon and guest vocalists, and is more of a hybrid of bass genres as opposed to just dubstep.
What do you hope listeners take away from your music?
We just hope they are able to either escape from reality when listening to it and have a good time, or identify with an emotion and relate to what the message is in each song. That's the beauty of music. It's the great escape through feeling the emotions put forth by the beats!
DJ Python Releases Mellow, Melancholic EP 'Club Sentimientos Vol. 2'
I saw that you were building a new home studio, how's that coming along and how will that affect your production process?
The building of the studio is done! We are just waiting for the last bit of equipment to show up and it's good to go. It will affect our production process a few ways. We will be able to record vocals without going to another studio. Plus we will also have a solid mixing and mastering room, so we don't have to work in headphones and then check the mix in a bunch of other studios. It should make it so we can take songs to completion much faster.
Trends in dance music seem to come and go, what are your thoughts on the current trends and where do you see the culture progressing?
That's a broad question considering the scope of dance music these days, so I will focus on the trends of our bass music corner. There's definitely a trend of a lot of really interesting hybrid music that is somewhere between trap and dubstep. There is also a trend of really cool forward thinking trap like NGHTMRE. The bassline house trend is also really cool as it allows artists like us to play some 4/4 in our sets and have our fans like it. Where we see it going is sort of an anything goes atmosphere as far as sounds and bpms….and we love that!
Aside from music, how do you like to spend your free time? Any other interests that help take your mind off the music industry?
Unfortunately, I (chris) don't have much time to get away from the music industry. When I do have some time I enjoy relaxing with my wife, going out to eat and trying to take as many vacations as possible. Jon likes to play video games and go backpacking with his girlfriend amongst other nerd activities hahaha.
What's next for you this year and what should we be looking forward to?
We have some music coming with Adventure Club. We also have some music coming with Bare and Half Empty. We are working with vocalists Adara and Tima Dee on some music. We also have a bunch of new remixes and solo music coming. Check us out at Paradiso, Global Dance, 515 Alive, Big Dub or Imagine this summer to hear the new music! We also have a few club gigs and the Safe In Sound Festival tour coming up. Lots to look forward to.
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Statik Link's Renaissance EP Delivers a Strong Showing of Raw Bass Music [Premiere]


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Lady Barons defeat Muskingum in home match
By: Mark Borek
MARK BOREK
In a thrilling Wednesday night matchup, the Franciscan University women's soccer team dominated non-conference Muskingum College competition in a 5-0 showcase well indicative of positive things to come for the Lady Barons.
The team jumped out to a quick lead in the form of three goals in the first 30 minutes of play. Junior Sarah Luebking opened up the scoring just before the 10:00 mark by converting a penalty kick, the result of a Muskingum infraction deep in the FUS backfield.
Junior midfielder Elizabeth Dawyot added her name to the score sheet shortly afterward, following Luebking by registering a corner header in the 19th minute. Eight minutes later, Leubking drove home her second goal of the evening, giving the Lady Barons a commanding 3-0 halftime lead.
Photo by Ulises Iniguez
The physical play of the Barons allowed them to impose their will early and often during the contest, and as the game wore on it became clear which way the victory would slide. Less than a minute into the second half, the Barons' leading scorer of the season, sophomore Kelsey Scott-Avery, added to the Franciscan lead with a quick strike.
Throughout the second half, the Lady Barons controlled the game. They were able to dominate the possession battle, as is evidenced by a registered 20 Franciscan shots on goal, compared to five from their Muskingum counterparts. Senior Corinne Jensen denied any chance of a Muskingum comeback, sending a goalie deflection into the back of the net in the 79th minute.
This game seems to signify good things to come for the Lady Barons, who impressed with their strong play from start to finish. The win was also freshman goalkeeper Marita Ostrich's first victory in a Franciscan uniform; her three saves helped to preserve the Franciscan shutout down the stretch.
The Lady Barons will next see the field on Tuesday at 4 p.m., as they take on visiting Washington & Jefferson at home.
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Popravljanje DNK je proces, v katerem celica prepozna in popravi poškodbo katere od molekul DNK, ki sestavljajo njen genom.

Poškodbe lahko povzročajo bodisi normalni presnovni procesi, bodisi okoljski dejavniki, kot je ionizirajoče sevanje; pri človeku se to zgodi več desettisočkrat na dan v vsaki celici. Vključujejo kemično spreminjanje strukture nukleotidov, ki gradijo DNK, kot je deaminacija, depurinacija ali oksidacija, vezava adduktov ipd. ter prekinjanje ene ali obeh verig DNK. To kvarno vpliva na sposobnost prepisovanja genov, s čimer ovira delovanje in preživetje prizadete celice ali hčerinskih celic po delitvi, nekatere poškodbe pa povzročijo tudi mutacije – spremembe zaporedja DNK.

Zato imajo organizmi v celicah stalno aktivne molekularne mehanizme v obliki kompleta encimov za popravljanje poškodb. Te molekule prepoznavajo neujemajoče se pare nukleotidov in prekinitve ter katalizirajo reakcije za popravilo. Odvisno od poškodbe je lahko to pri neujemajočih se parih preprosta direktna demetilacija (z metiltransferazo), izrezovanje in nadomeščanje nekomplementarnih nukleotidnih baz (z glikozilazami, endonukleazami, DNK-polimerazami in DNK-ligazami) ali izrezovanje krajših zaporedij nukleotidov (oligonukleotidov) in njihovo nadomeščanje (bolj zapleteni encimski kompleksi s helikazami, endonukleazami in ATP-azami, ki jih dopolnjuje aktivnost DNK-polimeraz in DNK-ligaz). Drugi encimski kompleksi popravljajo enoverižne ali dvoverižne prekinitve.

Evkariontske celice imajo tudi sistem transdukcije, ki zazna poškodbe dednine ali povzročitelja (na primer sevanje) in »rekrutira« mehanizme za popravljanje DNK na prizadeta območja. Zaradi njega je popravljanje DNK učinkovitejše in zmanjša se možnost napak zaradi netarčnega delovanja encimov za popravljanje. Poleg tega lahko v odvisnosti od obsega poškodb ali jakosti povzročitelja sproži kaskado drugih reakcij, ki sprožijo sistemski odziv organizma, kot je porjavelost kože ob izpostavljenosti UV-sevanju Sonca pri človeku. Na ravni celice lahko ti mehanizmi ob prevelikem obsegu poškodb sprožijo kontrolirano celično smrt ali nepovratno diferenciacijo celice v neaktivno obliko – t. i. celično senescenco.

Pomen
Poškodbe DNK ovirajo bodisi sintezo beljakovin, ki jih celica potrebuje za opravljanje svojih nalog, bodisi celično delitev, zato so mehanizmi za popravljanje ključni za preživetje organizma. Posebej so pomembni v tkivih, kjer se celice počasi nadomeščajo, denimo v živčevju. Kopičenje poškodb, ki jih mehanizmi popravljanja DNK ne morejo v popolnosti odpraviti, velja za enega glavnih mehanizmov staranja pri višjih organizmih; pri počasi delečih se celicah povzročajo odpoved funkcije tkiv in organov, pri hitro delečih pa povečujejo verjetnost za rakave spremembe, ko prizadenejo mehanizme za nadzor delitev. Normalna dolgoživost organizmov je odvisna od strategije preživetja določene vrste in bolj dolgoživi organizmi investirajo več energije v popravljanje DNK kot tisti s krajšo pričakovano življenjsko dobo (denimo če so bolj izpostavljeni plenilcem).

Genetske okvare sistema za odziv na poškodbe DNK pri človeku so bile prepoznane kot vzrok za različne dedne bolezni, povezane s prehitrim staranjem, močno povečano predispozicijo za raka in preobčutljivostjo na okoljske povzročitelje poškodb DNK, kot je kseroderma pigmentosum. Tudi sicer so mehanizmi popravljanja DNK deležni veliko pozornosti v medicini. Za odkritja na področju molekularnih mehanizmov popravljanja DNK so Tomas Lindahl, Paul Modrich in Aziz Sancar leta 2015 prejeli Nobelovo nagrado za kemijo.

Sklici

Mutacije
Celični procesi
Molekularna genetika
Staranje

redpajama_set_name: RedPajamaWikipedia


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Home Formula 1 6 F1 and MotoGP drivers about their favourites, training and toughest opponents
6 F1 and MotoGP drivers about their favourites, training and toughest opponents
Kaloyan Petrov
What happens when you put six young racers in a room and leave them to ask the questions? Max Verstappen, Pierre Gasly, Daniil Kvyat, Alex Albon, Andrea Dovizioso and Pol Espargaró found themselves both quizmasters and under the question spotlight in a novel Q&A session in Kitzbühel before the start of their respective Formula 1 and MotoGP seasons.
Dovizioso revealed his toughest ever rival, Albon his worst habit and Gasly his biggest friend-turned-rival on the grid. Here are some of the highlights:
Max Verstappen: "What's your favourite circuit."
Daniil Kvyat: "Everywhere where the car is fast is a good track. I like Monza, and I also like Mugello when I raced there in Formula Renault."
MV: "For me, it's Spa. I hate it when you really have to break hard and then there's a hairpin where you accelerate again. I prefer to be in the flow and being in the fast corners. So, Spa and there's a lot of orange there.
DK: "What's your favourite part of training and why?"
MV: "When it's finished! I enjoy riding a bicycle, cycling outside is good. I enjoy that."
Pol Espargaró: "Who's been your toughest opponent to date and what makes them so tough to beat?"
Andrea Dovizioso: "In the last few years for sure Marc [Márquez]. He won the last four, five titles, quite a lot. He likes to play on the limit and this is something for a rider that's not so easy. Everybody wants to stay a little bit under the limit but he wants to touch and play, maybe like Max. He plays with the limit every lap so that's his style and characteristic but I'm working on that."
AD: "Who's your all-time favourite sports star."
PE: "It's Alex Barros. When I was a child I was doing the Spanish championship and had a manager who knows Alex. I was at Catalan GP and my manager brought me to meet him. This guy let me go inside the motorhome. He was so kind with me so he treated me with so much respect being so little."
Alex Albon: "Who's your best friend in the paddock and what connects you?"
Pierre Gasly: "The one I know the longest time is Charles Leclerc. We used to spend holidays with each other when eight or nine years old. We started racing the same year, 2005, and after we grew more or less in the same series. He's the one I've known the longest time and spend most time with after the paddock."
PG: "What's your worst habit? You're perfect maybe that's the answer!?"
AA: "I'm always overthinking, overthinking in general. Not too much else to say."
Testing completed! Can't believe how quick it's gone! Lots learnt, just some final preparations now before Melbourne! 🇦🇺 🛫 #ToroRosso #HondaRacingF1 #RedBull #AA23 pic.twitter.com/usDsAwVKzU
— Alex Albon (@alex_albon) March 1, 2019
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A big, exuberant nose of mocha and black cherry aromas, cradled with notes of five-spice and black licorice. The palate had a pleasant jammy entry with plum and black cherry fruit. Plushy, velvety fruit on the finish with soft tannin to remember that it is really Cabernet.


Well, the new year is finally upon us and those of us who have new years resolutions last year to loose weight were you successful? I know that myself and my husband we not all that successful. My husband was doing good until he injured his shoulder. He goes to the doctor on Tuesday to see how bad the injury is. I hope that it is not to bad. He really needs to be working out to loose some of that unsightly weight. In his face and his spare tire. If his injury is worse that I hope it is maybe we can get him on some weight loss pills to help him curb his appetite and boost his weight loss. I would really like to see him that way he was before we met.
Unfortunately, there are so many weight loss pills on the market I do not want to get one that is going to harm him or myself. I am still kind of undecided on weight loss pills. Which one or ones are the best weight loss pills and will do what they claim to do and cause bad side effects. Of course I want one that does not cost to much but will do a good job.
Maybe I will just need to get him to a doctor and him evaluated and get him a good weight loss program with exercise and proper eating to get him down to a good manageable weight and awesome looking body.