Action for the ActivateLicense operation.
Represents any action executed on Amazon EC2.
Action for the AllocateAddress operation.
Action for the AssociateAddress operation.
Action for the AssociateDhcpOptions operation.
Action for the AssociateRouteTable operation.
Action for the AttachInternetGateway operation.
Action for the AttachNetworkInterface operation.
Action for the AttachVolume operation.
Action for the AttachVpnGateway operation.
Action for the AuthorizeSecurityGroupEgress operation.
Action for the AuthorizeSecurityGroupIngress operation.
Action for the BundleInstance operation.
Action for the CancelBundleTask operation.
Action for the CancelConversionTask operation.
Action for the CancelExportTask operation.
Action for the CancelSpotInstanceRequests operation.
Action for the ConfirmProductInstance operation.
Action for the CopySnapshot operation.
Action for the CreateCustomerGateway operation.
Action for the CreateDhcpOptions operation.
Action for the CreateImage operation.
Action for the CreateInstanceExportTask operation.
Action for the CreateInternetGateway operation.
Action for the CreateKeyPair operation.
Action for the CreateNetworkAcl operation.
Action for the CreateNetworkAclEntry operation.
Action for the CreateNetworkInterface operation.
Action for the CreatePlacementGroup operation.
Action for the CreateRoute operation.
Action for the CreateRouteTable operation.
Action for the CreateSecurityGroup operation.
Action for the CreateSnapshot operation.
Action for the CreateSpotDatafeedSubscription operation.
Action for the CreateSubnet operation.
Action for the CreateTags operation.
Action for the CreateVolume operation.
Action for the CreateVpc operation.
Action for the CreateVpnConnection operation.
Action for the CreateVpnGateway operation.
Action for the DeactivateLicense operation.
Action for the DeleteCustomerGateway operation.
Action for the DeleteDhcpOptions operation.
Action for the DeleteInternetGateway operation.
Action for the DeleteKeyPair operation.
Action for the DeleteNetworkAcl operation.
Action for the DeleteNetworkAclEntry operation.
Action for the DeleteNetworkInterface operation.
Action for the DeletePlacementGroup operation.
Action for the DeleteRoute operation.
Action for the DeleteRouteTable operation.
Action for the DeleteSecurityGroup operation.
Action for the DeleteSnapshot operation.
Action for the DeleteSpotDatafeedSubscription operation.
Action for the DeleteSubnet operation.
Action for the DeleteVolume operation.
Action for the DeleteVpc operation.
Action for the DeleteVpnConnection operation.
Action for the DeleteVpnGateway operation.
Action for the DeregisterImage operation.
Action for the DescribeAddresses operation.
Action for the DescribeAvailabilityZones operation.
Action for the DescribeBundleTasks operation.
Action for the DescribeConversionTasks operation.
Action for the DescribeCustomerGateways operation.
Action for the DescribeDhcpOptions operation.
Action for the DescribeExportTasks operation.
Action for the DescribeImageAttribute operation.
Action for the DescribeImages operation.
Action for the DescribeInstanceAttribute operation.
Action for the DescribeInstances operation.
Action for the DescribeInstanceStatus operation.
Action for the DescribeInternetGateways operation.
Action for the DescribeKeyPairs operation.
Action for the DescribeLicenses operation.
Action for the DescribeNetworkAcls operation.
Action for the DescribeNetworkInterfaceAttribute operation.
Action for the DescribeNetworkInterfaces operation.
Action for the DescribePlacementGroups operation.
Action for the DescribeRegions operation.
Action for the DescribeReservedInstances operation.
Action for the DescribeReservedInstancesOfferings operation.
Action for the DescribeRouteTables operation.
Action for the DescribeSecurityGroups operation.
Action for the DescribeSnapshotAttribute operation.
Action for the DescribeSnapshots operation.
Action for the DescribeSpotDatafeedSubscription operation.
Action for the DescribeSpotInstanceRequests operation.
Action for the DescribeSpotPriceHistory operation.
Action for the DescribeSubnets operation.
Action for the DescribeVolumeAttribute operation.
Action for the DescribeVolumes operation.
Action for the DescribeVolumeStatus operation.
Action for the DescribeVpcs operation.
Action for the DescribeVpnConnections operation.
Action for the DescribeVpnGateways operation.
Action for the DetachInternetGateway operation.
Action for the DetachNetworkInterface operation.
Action for the DetachVolume operation.
Action for the DetachVpnGateway operation.
Action for the DisassociateAddress operation.
Action for the DisassociateRouteTable operation.
Action for the EnableVolumeIO operation.
Action for the GetConsoleOutput operation.
Action for the GetPasswordData operation.
Action for the ImportInstance operation.
Action for the ImportKeyPair operation.
Action for the ImportVolume operation.
Action for the ModifyImageAttribute operation.
Action for the ModifyInstanceAttribute operation.
Action for the ModifyNetworkInterfaceAttribute operation.
Action for the ModifySnapshotAttribute operation.
Action for the ModifyVolumeAttribute operation.
Action for the MonitorInstances operation.
Action for the PurchaseReservedInstancesOffering operation.
Action for the RebootInstances operation.
Action for the RegisterImage operation.
Action for the ReleaseAddress operation.
Action for the ReplaceNetworkAclAssociation operation.
Action for the ReplaceNetworkAclEntry operation.
Action for the ReplaceRoute operation.
Action for the ReplaceRouteTableAssociation operation.
Action for the ReportInstanceStatus operation.
Action for the RequestSpotInstances operation.
Action for the ResetImageAttribute operation.
Action for the ResetInstanceAttribute operation.
Action for the ResetNetworkInterfaceAttribute operation.
Action for the ResetSnapshotAttribute operation.
Action for the RevokeSecurityGroupEgress operation.
Action for the RevokeSecurityGroupIngress operation.
Action for the RunInstances operation.
Action for the StartInstances operation.
Action for the StopInstances operation.
Action for the TerminateInstances operation.
Action for the UnmonitorInstances operation.


Best way to create a new number on top of plan?
Can I port my number with a zero balance??
Trace Cell number to address ?
Porting Tracfone number to Mint Mobile?
How do I remove "my number" from my old V60s after a master reset?
Sprint Executive Customer Service number?
What can go wrong when porting a number???


text:
Hyposcada richardsi är en fjärilsart som beskrevs av Fox 1941. Hyposcada richardsi ingår i släktet Hyposcada och familjen praktfjärilar. Inga underarter finns listade i Catalogue of Life.

Källor

Praktfjärilar
richardsi

redpajama_set_name: RedPajamaWikipedia


One of the best tourist attraction to go and see during your short stay in Dublin and only a stones throw from the Guinness Storehouse, Kilmainham Gaol is a must see for any discerning traveler. It was first built in 1796 and was called the New Gaol to distinguish it from the old gaol and was intended to replace a dungeon.
The uprisings of 1798, 1803, 1848, 1867 and 1916 all ended with the leaders confined in Kilmainham gaol including Robert Emmet, Thomas Francis Meagher, Charles Stewart Parnell and the 1916 Easter Rising leaders were all visitors, but it was the executions in 1916 which etched Kilmainham Gaol into Irish minds.
Prisoners in the Gaol would have to share the same room with kids, women and men all sharing the same cell with one candle to light up the room.
Kilmainham Gaol is located just outside Dublin' city centre about a 10 drive from Dublin's O Connell street heading towards Heuston train station.


Jim Went to be with the Lord on Sunday, September 2, 2018 after a long battle with cancer. He was born Monday, May 23, 1966, in Decatur, Alabama to Doyle Roberts and Martha Ann LeCroix Roberts. Jim was a Christian and a member of New Center Baptist Church, was United States Army Veteran of Desert Storm, now retired. He was a driver for T & T Trucking and had also driven for UPS Freight . He was preceded in death by his parents and a sister: Debbie Whitt.
Pallbearers will be Johnny Beard, Jimmy Walker, Craig Terry, Pat Halbrooks, Bill Parker, Frankie Moore.
Family would like to offer a "Special Thanks" to Southern Care-New Beacon Hospice and Special Hospice Nurse, Anna Dove and the his wonderful, loving and caring Church family.


Build a media or 'PR' web page on your website that showcases newsworthy information regarding your company. Journalists are always looking for story angles and your job is to make it easier for your company to be the story. By giving the media a jumpstart via a media page, you have a greater chance of the story being about your brand. Be sure to have a download section that includes your company's logo and important company imagery.
You can read studies that been done on the psychological impact of web design and it's effects on Internet marketing. A person's perception of a brand or product can be significantly impacted by psychological aspects of the website, such as the layout, color scheme and theme. You can apply this information in order to increase your profits.
Before you even get started as an internet marketer, make sure that your business correctly reflects what you're attempting to sell. A name says it all in this modern age. McDonald's is the exception; Burger King is the rule. If you can understand that, you're on your way to finding a great business name.


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Home > News > WATCH LIVE: GPS III SPACE VEHICLE 04 MISSION
WATCH LIVE: GPS III SPACE VEHICLE 04 MISSION
October 1, 2020 October 1, 2020 Rod Washington
SpaceX is targeting Friday, October 2, for a Falcon 9 launch of the GPS III Space Vehicle 04 mission from Space Launch Complex 40 (SLC-40) at Cape Canaveral Air Force Station in Florida. The 15-minute launch window opens at 9:43 p.m. EDT, or 01:43 UTC on October 3. Following stage separation, SpaceX will land Falcon 9's first stage on the "Just Read the Instructions" droneship, which will be stationed in the Atlantic Ocean. The spacecraft will deploy approximately 1 hour and 29 minutes after liftoff.
Last week, the United States Space Force's Space and Missile Systems Center (SMC) announced an agreement with SpaceX to launch previously flown boosters on future National Security Space Launch (NSSL) missions. You can watch the space vehicle launch webcast here, starting about 15 minutes before liftoff.
TNC Science
News Space and Tech Falcon 9, GPS III, Space Vehicle, SpaceX, United States Space Force
Honda Performance Development Names David Salters President
Lomo Saltado – Steak & French Fry Stir Fry
2020 Tied for Warmest Year on Record, NASA Analysis Shows

redpajama_set_name: RedPajamaCommonCrawl


I have found no guest bloggers / no guest posting opps. What's up? | Guest Blogging Community Help – #MyBlogGuest - Helping our members to succeed with guest blogging!
I have found no guest bloggers / no guest posting opps. What's up?
MyBlogGuest is just a platform. It is not a tool or a service. To get any benefit, you need to commit: to post at forums, help others and "socialize". Like any community it will only help active users who are ready to devote time to make friends and contacts.


Both updos and braided hairstyles are extremely charming and versatile, and the combination of these two will be something simply irresistible. With braids being always very stylish, learning a few creative ideas of sporting this trend is certainly advised. What about braided updos? These hairstyles can look utterly sophisticated and innocent and will never go by unnoticed. Thus, if you have long locks and want to give them a stylish boost, at the same time flaunting your femininity and romantic side, a low braided updo is just the thing for you.
At first sight a low braided updo may seem to be quite a difficult hairstyle to sport, however it doesn't require much profound hair styling skills or techniques. All you need is a little time for practicing, after which you can get this chic 'do in no time. So if you are ready to learn how to style a low braided updo, grab your bobby pins and a hair elastic and go crazy!
The great thing about the low braided updo hairstyle is that it can be created on all types of hair, though it looks best on sleek straight and soft hair. Even if you don't have long locks, you can turn to temporary hair extensions, as they come in a variety of shades to match every hair color.
To start styling a low braided updo, part your hair on the side. If you already have bangs, keep your hair parted as usual and start right from there. Start braiding your hair from one side of the head. Take parts of your hair and incorporate them into the braid, as you go towards the back part of your head in a descending pattern. This technique is known as French braiding, and it requires a little bit of practice before you'll be able to get a flawless braid without getting frustrated.
Once you reach the other side of the head, keep braiding your hair to create a braided side swept ponytail. At the end, secure your pony with a hair elastic and pull the braids apart gently to get that romantic loose effect. The last step is to hide the loose part under the hair by tucking it in and securing with bobby pins. Your low braided updo is ready to rock!
This easy-to-sport and lovely look is very versatile and looks perfect both for every day wear and for those special occasions. For a better idea, take a look at the great tutorial below and practice your braiding skills to be able to create amazing braided hairstyles in just a few minutes.


The extent of lung involvement visualized by high-resolution computed tomography (HRCT) is a predictor of decline in forced vital capacity (FVC) in scleroderma–interstitial lung disease. Our objective was to evaluate the performance of three different HRCT-defined staging systems in the Scleroderma Lung Study I (SLS I) over a 1-year period.
We assessed two visual semiquantitative scores: the maximum fibrosis score (MaxFib, the fibrosis score in the zone of maximal lung involvement) and visual assessment of total lung involvement (TLI) as proposed by Goh and Wells. In addition, we evaluated the computer-aided diagnosis and calculated the quantitative percentage with fibrosis (QLF) and TLI.
The mean duration of the disease was 3.2 years, and the mean FVC was 67.7 %. Regardless of the staging system used, a greater degree of fibrosis/TLI on HRCT scans was associated with a greater decline in FVC in the placebo group. Using the MaxFib and QLF, the mean absolute changes in FVC from baseline were 0.1 % and −1.4 %, respectively, in <25 % lung involvement vs. a change of −6.2 % and −6.9 %, respectively, with >25 % involvement (negative score denotes worsening in FVC). Conversely, cyclophosphamide was able to stabilize decline in FVC in subjects with greater degree of involvement detected by HRCT. Using the visual MaxFib and QLF, the mean absolute improvements in FVC were 1.2 and 1.1, respectively, with >25 % involvement.
HRCT-defined lung involvement was a predictor of decline in FVC in SLS I. The choice of staging system for cohort enrichment in a clinical trial depends on feasibility.
ISRCTN15982171. Registered 19 Aug 2015.
Systemic sclerosis–associated interstitial lung disease (SSc-ILD) is common, is associated with a poor prognosis, and is the leading cause of death in people with SSc . The pathogenesis of SSc-ILD involves a complex interplay of vascular injury, inflammation, and fibrosis (reviewed in [2–6]). The most common pathological finding in lung biopsies of patients with SSc-ILD (approximately 78 % patients) is nonspecific interstitial pneumonia . Usual interstitial pneumonia, the pathological finding in idiopathic pulmonary fibrosis (IPF), as well as other patterns are present in approximately 10–15 % of patients with SSc-ILD . However, open lung biopsy is usually not performed for SSc-ILD, and high-resolution computed tomography (HRCT) has become the gold standard for diagnosis and classification of ILD [8, 9]. In addition to diagnosis of ILD, moderate to severe fibrosis or total lung involvement (TLI) by SSc-ILD visualized on the baseline HRCT scan is an independent predictor of response to cyclophosphamide (CYC) therapy , poor survival , and future decline in percentage of predicted forced vital capacity (FVC% predicted) .
Recent trials have included forced vital capacity (FVC), which has traditionally served as the primary endpoint in SSc-ILD clinical trials as it is available. It has low measurement error (if done using standardized methodology) and is sensitive to change in treatment. However, treatment with CYC had only modest effects on FVC in the Scleroderma Lung Study I (SLS I) [13, 14] and the Fibrosing Alveolitis in Scleroderma Trial (FAST) . Therefore, there is increased interest in enriching this cohort of patients with rapid disease progression for effective identification of patients at high risk of ILD progression, as well as for early intervention .
Different HRCT staging systems have been developed to quantify the extent of lung involvement–semiquantification by visual assessment or quantification using computer-assisted methodology. Kazerooni et al. developed a semiquantitative measure to assess ground-glass opacity (GGO), reticulations with architectural distortion and traction bronchiectasis ("fibrosis"), and honeycomb cysts (HCs) , and the overall score correlated well with assessment of ILD in pathological specimens . A modified Kazerooni visual scoring system was used for SLS I, a placebo-controlled trial of oral CYC in patients with symptomatic SSc-ILD in which the extent of reticulations ("fibrosis"), GGO, and HCs was scored semiquantitatively. In addition, a novel algorithm was developed to quantify the presence and extent of both fibrosis and total ILD (sum of scores for fibrosis, GGO, and HCs) using the computer-aided diagnosis (CAD) technology in three area-equivalent zones (upper, middle, and lower) as well as in the whole lung (WL) in SLS I [14, 18, 19]. CAD is based upon measurement of the density or texture features of each pixel and assignment of a score for the amount of abnormal lung tissue present. Quantitative assessment of total extent of interstitial lung disease (QILD) and of lung fibrosis (QLF) correlates well with the visual scoring systems and provides an objective determination of treatment efficacy in patients with SSc-ILD  (Additional file 1: Figure S1). Separately, Goh and Wells developed and validated a visual semiquantitative staging system for TLI (i.e., fibrosis, GGO, and HCs) in an observational cohort of patients with SSc-ILD .
We used individual patient data from the SLS I for current analysis. SLS I was a multicenter, double-blind, randomized controlled trial (RCT) conducted to evaluate the effectiveness and safety of oral CYC administered for 1 year in patients with symptomatic SSc-ILD who had evidence of ILD. The SLS I was the first RCT to demonstrate the effectiveness of CYC in FVC, relative to placebo, at the end of the 1-year treatment period . Although the physiological benefits of CYC compared with placebo were modest (2.53 % and 4.09 % improvements in FVC% predicted and total lung capacity, respectively, at 12 months; p < 0.03), these results were supported by parallel findings of improvement in patient-reported outcomes (health-related quality of life, cough, and dyspnea) [21, 22], as well as greater stability of fibrosis visualized by HRCT ([23–25] and summarized in ) and skin thickness scores. In addition, follow-up HRCT scans obtained at 12 months revealed that the change in extent of fibrosis from baseline was significantly worse in the placebo group than in the CYC treatment group . Our objective was to compare the performance in a post hoc analysis of different HRCT staging systems on FVC and diffusing capacity for carbon monoxide (DLCO) in SLS I over a 1-year period. Specifically, we sought to determine (1) whether an HRCT staging system can enrich for subjects who will most likely decline in the placebo group and (2) the effects of HRCT staging system on the expected changes in FVC and DLCO in the CYC group that may inform the design of future trials. We chose a 1-year period on the basis of expert consensus that SSc-ILD trials should be at least 1 year .
SLS I consisted of 158 participants randomized to receive either oral CYC or a matching placebo for 1 year, followed by an additional year of observation off treatment, as previously published . Ethical approval was received from each participating institution and written informed consent was obtained from each subject. Briefly, inclusion criteria included age ≥18 years, duration of disease ≤7 years from onset of the first non-Raynaud's symptom of SSc, FVC% 40–85 %, DLCO ≥40 % predicted (or 30–39 % predicted in the absence of clinical evidence of pulmonary hypertension), and evidence of any GGO and/or positive bronchoalveolar lavage (≥3 % neutrophils and/or ≥2 % eosinophils). All subjects provided written informed consent, and the study was approved by the medical institutional review board at each clinical center. Please see the Acknowledgments section for the list of centers that participated in the study.
Baseline measurements included full pulmonary function tests (PFTs), including spirometry, lung volume (by body plethysmography), and DLCO. PFTs were read centrally for quality assurance. In addition to ascertainment of disease duration and presence of limited or diffuse cutaneous SSc, patient-centered measures (including dyspnea and quality-of-life indices) were obtained. HRCT scans were obtained at baseline with the patient in prone position and at maximal inspiration. The images were acquired from scanners with at least four multidetectors according to a standardized protocol. Nonvolumetric computed tomographic scans of –2-mm slice thickness acquired at 10-mm increments were acquired contiguously. More details are available elsewhere .
In SLS I, HRCT scans were scored by two independent radiologists who used a Likert scale (0 = absent, 1 = 1–25 %, 2 = 26–50 %, 3 = 51–75 %, and 4 = 76–100 %) for extent of four categories of parenchymal abnormality (pure GGO), lung fibrosis, HCs, and emphysema) . The scoring was performed for each of the three zones (upper, extending from apex to aortic arch; middle, from aortic arch to inferior pulmonary vein; and lower, from inferior pulmonary veins to base) in each lung, as well as for the WL. The visual maximum fibrosis score (MaxFib) was individually reviewed by two thoracic radiologists who scored fibrosis in the zone of maximal involvement (ZM). Discordant interpretations were reviewed with a third radiologist to achieve consensus in a face-to-face meeting; no average scores were calculated. Quantitative maximum extent of fibrosis was also determined by CAD in the ZM.
Goh and Wells developed a prognostic algorithm for patients with SSc-ILD, integrating PFTs and HRCT . TLI was assessed in an observational cohort of patients with SSc-ILD. HRCT images were scored by two independent radiologists at five levels: (1) origin of great vessels, (2) main carina, (3) pulmonary venous confluence, (4) halfway between the third and fifth sections, and (5) immediately above the right hemidiaphragm. HRCT variables were total disease extent that incorporated the extent of a reticular pattern, GGO, and HCs. The extent of ILD was estimated as a percentage of total volume to the nearest 5 % in each of the five sections. Global extent of disease determined by HRCT was calculated as the mean extent score in the five scored sections. This was stratified as <20 % vs. >20 % TLI (termed Goh and Wells unadjusted stratification). For indeterminate cases (extent of TLI 10–30 % because there may be measurement error by visual read), an FVC threshold of 70 % is an adequate prognostic substitute. On the basis of these observations, Goh and Wells staged global extent of disease as limited or minimal disease (minimal disease determined by HRCT or, in indeterminate cases, FVC ≥70 %) or extensive disease (severe disease determined by HRCT or, in indeterminate cases, FVC <70 %) . This aspect has been termed Goh and Wells adjusted stratification.
To obviate interreader variation and to standardize data across multiple sites, a CAD was developed using the SLS I data . The HRCT scans from SLS I were reconstructed with sharp or manufacturer-recommended overenhancing filters. The CAD system segmented each lung of each patient into three area-equivalent zones (upper, middle, and lower). After semiautomated lung segmentation, the images were entered into a quantitative image workstation to produce separate quantitative scores for reticulations (fibrosis), GGO, and HCs automatically . The QILD score was the sum of all abnormally classified scores, including scores for fibrosis, GGO, and HCs. HRCT QLF scores were determined using the percentage of counts in which the classified abnormal pattern comprised reticular opacity with architectural distortion. QILD and QLF scores were summed for both the WL, including both lungs, and the ZM.
A 25 % threshold for the QILD and QLF in the ZM was agreed a priori to be consistent with a visual MaxFib cutoff of 25 % (which assesses area of maximum fibrosis). In addition, we agreed to a 20 % cutoff for QILD and QLF in the WL to be consistent with a Goh and Wells threshold of 20 % for TLI.
We analyzed HRCT data in two different ways. First, we assessed the strength of associations between each staging system and FVC or DLCO percentage of predicted value at baseline, as well as the change in FVC and DLCO percentage of predicted value from baseline to 12 months using Pearson correlation coefficients. A coefficient ≥0.40 was considered to be a moderate association . Second, we stratified the staging system (e.g., 0–25 % vs. 26–100 % for visual MaxFib) on the basis of published data to assess if this could enrich for subjects in the placebo group who would decline over a 1-year period. Two-sample t tests were used to assess statistical significance for absolute and relative change (percentage of predicted change from baseline) in FVC and DLCO over a 1-year period. Fisher's exact test or a χ2 test was used to compare categorical variables among categories within the different staging systems. All tests were two-sided, and a p value <0.05 was considered statistically significant. All analyses were performed using SAS 9.3 software (SAS Institute, Cary, NC, USA).
Of the 158 patients, 93 (48 patients in the placebo group and 45 patients in the CYC group) had FVC data available at baseline and 12 months as well as good-quality baseline HRCT scans. These patients were included in the analysis. There were no significant differences in baseline characteristics between the two treatment groups (Table 1). These patients' mean age was 47 years, and their mean disease duration was 3.2 years. Their mean (standard deviation [SD]) FVC was 67.7 % (11.9) of predicted, and their mean (SD) DLCO was 46.3 % (12.7) of predicted.
First, we assessed the relationships between the scoring systems as continuous variables and change in FVC and DLCO. In the placebo group, when absolute changes in FVC and DLCO were considered, correlations between the staging systems were largely negative but none were significant (Table 2). Conversely, these correlations were positive in the CYC group, suggesting that CYC treatment had a positive impact on FVC and DLCO in patients with a greater degree of ILD (assessed using different staging systems).
Next, we assessed whether various scoring systems, when dichotomized into mild vs. extensive disease, could predict change in PFTs. The absolute decline in FVC based on different staging systems is shown in Table 3 and Fig. 1. In the placebo group, regardless of the staging system used, there was a decline in FVC in patients with more extensive disease. For example, for MaxFib, the mean (SD) percentage decline in FVC was −6.2 (12.5) with >25 % involvement and 0.1 (9.0) (mild improvement) with <25 % involvement (p = 0.01). When we used the Goh and Wells unadjusted stratification for extent of ILD involvement, the mean (SD) declines in FVC were −1.6 (10.2) with <20 % lung involvement and −5.5 (8.0) with >20 % involvement. Similar trends were observed in the CAD staging system. When we used QILD for WL involvement, patients with >20 % involvement had a decline of −4.9 (9.5) vs. improvement of 0.3 (6.8) for <20 % involvement. Similar trends were also seen when change from baseline was expressed as relative decline in FVC percentage of predicted value (Additional file 2: Table S1).
In the CYC arm, nonsignificant changes in FVC were noted across the various staging systems, most notably in patients with greater involvement visualized by HRCT (Table 3 and Additional file 2: Table S1). In the MaxFib group, a small improvement in FVC was seen in patients with >25 % involvement (1.2 [6.6]; p = 0.04). Although not statistically significant, similar changes were seen in the Goh and Wells unadjusted stratification, the Goh and Wells adjusted stratification, and the CAD staging systems.
The absolute decline in DLCO in relation to the choice of staging systems is shown in Table 4. In the placebo group, a statistically significant difference in DLCO was observed in QILD-WL staging by CAD (<20 %, 4.8 [8.6]; >20 %, −4.3 [10.6]; p = 0.01). Although statistical significance was not reached in the other staging systems, the mean changes in DLCO showed a trend toward a significant difference in patients with greater HRCT involvement in the placebo group. A larger variability was noted in the CYC arm, with a statistically significant effect on Goh and Wells adjusted stratification (minimal −1.3 [7.9] vs. extensive −6.9 [6.9]; p = 0.4) (Table 4).
As somewhat effective therapies for other manifestations of SSc (e.g., renal, pulmonary arterial hypertension, and articular) have emerged [27, 28], the morbidity and mortality of ILD have become increasingly apparent [29–31]. Traditionally, the severity of SSc-ILD is defined by the degree of ventilatory restriction in conjunction with the magnitude of diffusion impairment. These physiological measures are indirect and highly variable surrogates for the extent of structural disease abnormality . In contrast, the extent of ILD visualized on HRCT images (fibrosis, GGO, and/or HCs) is a more direct and precise indicator of the severity of the underlying pathological process [10–12, 20] and is associated with mortality .
With increasing interest in optimizing the design of clinical trials for evaluation of interventions for SSc-ILD, it is important to reliably identify cohorts of patients with a higher risk of disease progression and a greater likelihood of a favorable response to disease-modifying therapy. This process of cohort enrichment consists of the selective enrollment of these patients in treatment studies, reducing the patient numbers required to demonstrate a treatment effect, and increasing the average amplitude of such a benefit . Our group previously published post hoc multivariate regression analyses  using the SLS I and identified that fibrosis at baseline determined by HRCT, the modified Rodnan skin thickness score (MRSS), and the Mahler Baseline Dyspnea Index as independent correlates of treatment response to CYC. When patients were stratified on the basis of whether 50 % or more of any lung zone was involved by reticular infiltrates in the ZM as determined by HRCT, as assessed by visual scoring, and/or whether patients exhibited an MRSS ≥23 (0–51 scale), a subgroup of patients emerged in whom there was an average CYC treatment effect of 9.81 % at 18 months (p < 0.001). Conversely, there was no treatment effect (−0.58 % difference) in patients with less severe HRCT findings and a lower MRSS at baseline.
The present study represents another step toward defining cohort enrichment for clinical trials. We compared three different staging systems used to quantify the extent of ILD on HRCT: the visual MaxFib score, the Goh and Wells criteria, and the CAD quantitative scores for fibrosis (QLF) and TLI (QILD). In the placebo group, patients categorized as having moderate to extensive ILD on the basis of any of the three staging systems had a larger absolute decline in FVC (Table 3). Although MaxFib had the highest statistical significance for the placebo group, the differences in absolute changes in FVC between different staging systems were small and had similar trends in decline of FVC with greater HRCT involvement. In the CYC arm, there was stabilization in FVC in patients with extensive disease visualized by HRCT across all the staging systems. Interestingly, higher HRCT-assessed involvement was associated with stabilization of FVC in the CYC group vs. average decline in the other HRCT group. Both MaxFib and QILD-ZM showed statistically significant changes. This is consistent with correlation coefficient data where there are positive correlations with change in FVC vs. different staging systems in the CYC group (Table 2). We also included detailed analysis for the CYC group based on preliminary data from the SLS II, a double-blind study of mycophenolate mofetil vs. CYC in patients with SSc with symptomatic ILD treated with oral mycophenolate mofetil for 2 years compared with oral CYC for 1 year followed by placebo during the second year . Interestingly, it appears that background CYC therapy negates the enrichment strategy using HRCT staging systems. The change in FVC was positive (suggesting stabilization and/or improvement) in the more severe HRCT lung involvement with all staging systems. This analysis can inform trial design in future studies in which researchers consider background immunosuppressive therapies.
FVC was used as the primary outcome measure in the SLS I and FAST studies. The treatment with CYC had only a modest effect on FVC in the SLS I [13, 14] and FAST trials, and clinicians have debated the meaning of these results in clinical care [34, 35]. On the basis of a recent viewpoint published by the U.S. Food and Drug Administration on FVC in IPF , we explored whether cohort enrichment in the SLS I population could have provided a more clinically meaningful change in FVC compared with the entire sample. Although not established for SSc-ILD, a change of 2–6 % is considered a minimally important change in IPF . Using different staging systems, we found that patients with extensive lung involvement determined by HRCT had clinically meaningful declines.
Using the SLS I and II, we recently showed that DLCO is the single best correlate of the extent of lung involvement determined by HRCT  and supported by the correlation coefficients between different staging systems vs. baseline DLCO (Table 3). However, DLCO has the high measurement error and lack of specificity (as it is influenced by both ILD and pulmonary vascular disease [16, 38]), and none of the staging systems were correlated with the change in DLCO over 1 year, highlighting that DLCO is a poor outcome measure in ILD trials.
Our analysis may have significant impact on clinical trial design. This information can be used to enrich patients who are recruited in future ILD trials, calculate sample size, and judge the feasibility of the trial. For example, using visual MaxFib score, 73 % of patients who participated in the SLS I would qualify for an enriched protocol. Although this analysis does not provide guidance regarding which staging system to incorporate, recent post hoc analyses from SLS I suggest that the CAD system is more sensitive to change than a visual scoring system [19, 23, 25, 32]. Therefore, if HRCT is planned as an outcome measure (in addition to an enrichment criterion), then CAD is the preferred system [19, 23, 24], depending on its availability. Also, Goh and Wells criteria are applied only to the baseline HRCT and have not been evaluated in a longitudinal fashion. However, they have the advantage that they can easily be incorporated into observational studies . Conversely, the CAD system is not universally available, which may limit its feasibility.
Our study has much strength in its comparison of three staging systems that have been published for grading the extent of SSc-ILD and have been shown to be feasible for use in a clinical trial. In addition, we validated the Goh and Wells criteria in SLS I.
Our study is not without limitations. The analysis is a post hoc analysis and is limited to participants enrolled in a clinical trial with specific entry criteria, thereby limiting the generalizability of the findings. The number of subjects in the study is low, and further validation is needed in another cohort to confirm the results. Use of the staging system in other cohorts (including clinical trials and observational cohorts) should be carefully assessed before the findings are generalized.
The extent of HRCT-quantified ILD is a predictor of decline in FVC over a 1-year period and is independent of the staging system used to classify extent of disease. The choice of the staging system in a clinical trial depends on feasibility and available expertise but should be validated before incorporating it in future studies.
Anonymized data from SLS I are available to investigators by application to the SLS I Executive Committee (DPT: dtashkin@ mednet.ucla.edu).
The following people and institutions participated in the Scleroderma Lung Study I: University of Michigan, Ann Arbor: D. Khanna; University of California at Los Angeles (UCLA), Los Angeles: P. J. Clements, D. P. Tashkin, R. Elashoff, J. Goldin, M. Roth, D. Furst, K. Bulpitt, W.-L. J. Chung, S. Viasco, M. Sterz, L. Woolcock, X. Yan, J. Ho, S. Vasunilashorn, and I. da Costa; University of Medicine and Dentistry of New Jersey, New Brunswick: J. R. Seibold, D. J. Riley, J. K. Amorosa, V. M. Hsu, D. A. McCloskey, and J. E. Wilson; University of Illinois at Chicago, Chicago: J. Varga, D. Schraufnagel, A. Wilbur, D. Lapota, S. Arami, and P. Cole-Saffold; Boston University, Boston, MA: R. Simms, A. Theodore, P. Clarke, J. Korn, K. Tobin, and M. Nuite; Medical University of South Carolina, Charleston: R. Silver, M. Bolster, C. Strange, S. Schabel, E. Smith, J. Arnold, K. Caldwell, and M. Bonner; The Johns Hopkins University School of Medicine, Baltimore, MD: R. Wise, F. Wigley, B. White, L. Hummers, M. Bohlman, A. Polito, G. Leatherman, E. Forbes, and M. Daniel; Georgetown University, Washington, DC: V. Steen, C. Read, C. Cooper, S. Wheaton, A. Carey, and A. Ortiz; University of Texas at Houston, Houston: M. Mayes, E. Parsley, S. Oldham, T. Filemon, S. Jordan, and M. Perry; University of California at San Francisco, San Francisco: K. Connolly, J. Golden, P. Wolters, R. Webb, J. Davis, C. Antolos, and C. Maynetto; University of Alabama at Birmingham, Birmingham: B. Fessler, M. Olman, C. Sanders, L. Heck, and T. Parkhill; University of Connecticut Health Center, Farmington: N. Rothfield, M. Metersky, R. Cobb, M. Aberles, F. Ingenito, and E. Breen; Wayne State University, Detroit, MI: M. Mayes, K. Mubarak, J. L. Granda, J. Silva, Z. Injic, and R. Alexander; Virginia Mason Research Center, Seattle, WA: D. Furst, S. Springmeyer, S. Kirkland, J. Molitor, R. Hinke and A. Mondt; Data Safety and Monitoring Board: Harvard Medical School, Boston, MA: T. Thompson; Veterans Affairs Medical Center, Brown University, Providence, RI: S. Rounds; Cedars Sinai Medical Center–UCLA Health System, Los Angeles, CA: M. Weinstein; Clinical Trials & Surveys, Baltimore, MD: B. Thompson; Mortality and Morbidity Review Committee: University of California, Los Angeles: H. Paulus and S. Levy; The Johns Hopkins University, Baltimore, MD: D. Martin. We are also grateful to Bristol-Myers Squibb for supplying cyclophosphamide for use in SLS I. SLS I was supported by grants from the National Institutes of Health (U01 HL60587, U01 HL60606, and R01 HL089758). DK was supported by a K24 grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health. This analysis was supported by an unrestricted grant from EMD Serono.
DK has or had a consultancy relationship with and/or has received research funding from Bayer, Biogen Idec, Bristol-Myers Squibb, Cytori Therapeutics, EMD Serono, Forward Pharma, Genentech/Roche, Lycera, Medac Pharma, Sanofi-Aventis/Genzyme, and Seattle Genetics. The other authors declare that they have no competing interests.
DK contributed to the data collection, design of the study, interpretation of the data, and the writing of the initial draft of the manuscript. VN contributed to the design of the study, interpretation of the data, and the writing of the initial draft of the manuscript. C-HT contributed to statistical analysis and the writing of the statistical analysis portion of the manuscript. FA and RS read the HRCT scans and provided comments on the manuscript. GK contributed to statistical analysis and interpretation of computer-aided HRCT, and also provided comments on the manuscript. AW provided input on the HRCT review and commented on the manuscript, DEF, PJC, MDR, DPT, and JG contributed to data collection, design of the study, and interpretation of the data, and also provided comments on the manuscript. All authors read and approved the final manuscript.
Tashkin DP, Volkmann ER, Tseng CH, Kim HJ, Goldin J, Clements P, et al. Relationship between quantitative radiographic assessments of interstitial lung disease and physiological and clinical features of systemic sclerosis. Ann Rheum Dis. doi:10.1136/annrheumdis-2014-206076.
Clements PJ, Tashkin D, Roth M, Khanna D, Furst DE, Tseng CH, et al. The Scleroderma Lung Study II (SLS II) shows that both oral cyclophosphamide (CYC) and mycophenolate mofetil (MMF) are efficacious in treating progressive interstitial lung disease (ILD) in patients with systemic sclerosis (SSc) [abstract 1075]. Arthritis Rheumatol. 2015;67(Suppl 10). http://acrabstracts.org/abstract/the-scleroderma-lung-study-ii-sls-ii-shows-that-both-oral-cyclophosphamide-cyc-and-mycophenolate-mofitil-mmf-are-efficacious-in-treating-progressive-interstitial-lung-disease-ild-in-patients-w/. Accessed December 12, 2015.


The Misadventures of PB Winterbottom (HD) Review & Gameplay!
The Misadventures of P.B. Winterbottom (HD) Review and Gameplay! Twitter: @ZeitgeistReview For a full write-up and screen-shots, head on over to http://www.
See the trailer for The Misadventures of P.B. Winterbottom!


The signature transmission project in Xcel Energy's Power for the Plains plan has been brought into service.
The 345kV transmission line between Xcel Energy subsidiary Southwestern Public Service Company's (SPS) Tuco substation north of Lubbock in northwest Texas to the Oklahoma state line has been energized. The connection is to an Oklahoma line segment built by Oklahoma Gas and Electric Company (OGE) from the Beckham County site to the city of Woodward.
This 320km (200 miles) line is the signature transmission project in Xcel Energy's Power for the Plains grid improvement plan. The 10-year, US$1.6 billion plan was given the go ahead in spring 2010 to develop new transmission lines spanning portions of Texas, New Mexico and Oklahoma. The aim is to help improve reliability while strengthening the existing transmission grid and providing outlet for additional renewable wind generation.
The total cost for Xcel Energy's portion of the TUCO line is approximately US$205 million, shared among the member utilities of the Southwest Power Pool, the regional transmission organization overseeing grid reliability in portions of eight south-central states, including the Texas Panhandle-South Plains region and eastern New Mexico.
In May, Xcel Energy and OG&E completed another major 345kV transmission connection between Hitchland, Texas, and Woodward.
● 68km (42 mile) of 239kV line connecting the Pleasant Hill substation with the Oasis and Roosevelt substations in New Mexico.
The other major project in Power for the Plains is a proposed 260km (159 mile) 345kV transmission line connecting the Tuco and Yoakum substations in Texas and the Hobbs Plant substation in New Mexico. The proposed in-service date is mid-2020. With upgrades to the existing Hobbs and Yoakum substations, this project will provide a significant source of bulk power capacity from the transmission hub at Tuco substation to the southwest portion of the transmission system in west Texas and eastern New Mexico.
In all, the latest plans up to 2020 approved by the Southwest Power Pool in May cover upgrades or modifications to nine existing substations and construction of 12 new substations, and construction of 240km (149 miles) of new 115kV transmission lines and 395km (245 miles) of new 345kV transmission lines.
With new connections such as the Tuco and Hitchland lines, Xcel Energy expects to take advantage of more opportunities to buy and sell power from the regional market. In the summer peak season, the company will also have access to more power to meet peak demand.
The new lines also boost the reliability of the area grid, offering more alternatives to move power into and around the area in the event of outages on other major lines. Additionally, they provide more export capacity for wind energy generated from area wind farms.


Better Because It Has To Be: 35535 Euclid Ave, Willoughby, OH.
You want the most delicious pizza in Willoughby. You want one that will knock your socks off and give you a smile to boot! At Jet's Pizza, being square is delicious! Our claim to fame is our incredibly cheesy, roasted veggie and golden Detroit-style square pizza with an out-of-this world crust that is Flavorized.
But wait ... there's more. Go for it all as you dive into Our Deep Dish delight; go for the gold with the classic hand-tossed pizza; feel like a New Yorker with a huge slice of the NY Style; or take a bite out of our crispy Thin Crust. Our stores even offer a pizza that is gluten-free!
You've waited long enough for best sauce in any hemisphere? Jet's pizza sauce is as outstanding as our 8-corner pizza! And we're not just talking delicious tomato sauce here. You'll want our homemade ranch sauce on everything you order! Your taste buds will have a party.
At your favorite Jet's location flavor is your new best friend. Want even more deliciousness? Flavorize your crust for free. Crust this good is a rare find indeed! Cajun, butter, sesame seed, poppy seed, garlic, Cajun, and Jet's Turbo! Mind blown! Oh, the cheering that will break out when we deliver. At your local Jet's Pizza on 35535 Euclid Ave, we're always serving hot and fresh pizza when hunger calls. Our mobile app is really easy to use and accepts orders, or you can order, from a laptop or phone us at (440) 954-7700. You also can drive to Jet's and place your order to go! We would love to see you.
We're not just known for crazy good pizza — we handcraft Steak & Cheese Deli Boats, Jet's Bread, enormous salads, and the most flavorful wings that will make game day and every day amazing!


Provides key antioxidants to revive dry lips.
One of my favorite things about this lip balm is that it has no shine! it doesn't feel waxy or heavy and doesn't feel greasy or slippery. It's moisturizing, smells & tastes good -and- has SPF25. A winner all around.


Knoxville, Tenn. (January 10, 2010) - SportDOG Brand® has announced it will award $1,000 to the Young Guns, a youth group that is part of the Illinois Pioneer chapter of Pheasants Forever, for use in restoring 44 acres of upland game habitat. This annual grant is being awarded as part of SportDOG Brand's Kids in Conservation Fund®.
"Our chapter's volunteers have used the Young Guns program to get hundreds of youths outdoors and participating in shooting sports, fishing and hunting," said Dave Kaeding, president of the Illinois Pioneer Pheasants Forever.
The restoration project, which will be carried out by members of the Young Guns and adult volunteers in Ford County, Illinois, calls for the removal of invasive trees, a prescribed burn, interseeding of native grasses and forbs, and the planting of white pine windbreaks.
"Not only will pheasants have an improved nesting and roosting area, but many other species, including deer and turkeys, will benefit from the restoration," Kaeding said.
SportDOG Conservation Fund® was created to support conservation organizations and projects SportDOG Brand® customers care about. In 2009, the company extended the project to include Kids in Conservation as a way to lend support to and recognize groups and individuals whose efforts ensure wise use of natural resources for generations to come.
"This is the first grant we've awarded to a youth group as part of Kids in Conservation," said Eleanor Marshall with SportDOG Brand®. "The forward-thinking approach of this Illinois Pheasants Forever chapter in creating the Young Guns is exactly the type of initiative we're proud to support."
For more information on the SportDOG Conservation Fund®, visit www.sportdog.com. Conservation leaders interested in learning about future grants are encouraged to contact Britney Starr at bstarr@sportdog.com.


Hello ladies, my name is Lisa Colon aka Trophy of Grace. My heart's desire is to let you know that you are not alone in your circumstances. Many others around the world and maybe even next door to you are going through or have gone through similar situations. I have been through so many different trials in my own personal life. Looking at me now you would never know. Here's a short version of my story.
For the most part I had a good early childhood. My parents always seemed very loving and affectionate towards one other. I don't really remember seeing them fighting. I used to play the keyboard very well and I was always a straight 'A' student. At the time I had just one sister who is a year younger than me.
My parents separated when I was eleven years old. This was very difficult for me because I was very close to my dad. I blamed my mother and resented her for their divorce. I began running away from home often. When I was just twelve years old I stole a car with a "friend" and drove to New York. That was just the first time that I stole a car and ran away. I thought I was so grown. It was hard to relate to the other girls my age because I felt like I was so much more "mature". I hung out with gangs but not by choice. My mother's family incorporated a gang called "Sangre" back in the early 90's. I saw several initiations along with other gang activities. I did not have many boyfriends because they were scared of my uncles and cousins. I learned to keep my relations with guys on the low.
My mother died when I was sixteen years old. That was it for me. I went down so low in my life that I never thought I would ever come out of that pit. I began selling and doing drugs. Just months after my mother died I got busted by the police and charged with drug trafficking. They put me on probation for five years.
Within a year I meet my first husband. I was pregnant and married six months later. A month before my daughter's 1st birthday he left us without any warning. I was heartbroken and lonely. I did not have a mother to go running home to and my father did not want my bad influence around my little brother. I was just nineteen years old and homeless. I had no choice but to leave my daughter with my in-laws who were pastors. By this time I had violated my probation for the third time. On my second violation the judge promised that he would send me to prison if I violated again. Months later I was arrested for assault with a vehicle. Even then the judge still had mercy on me and sentenced me to a six month drug rehab center. Just three months into the program I violated again.
While I was waiting to be taken back to jail from the center, a group of Christian women came in. They planned a big tea party event. It was beautiful. I had never been to anything like that. That is when I met my mentor. She is a godly woman who would impact the rest of my life. She began writing me. I loved reading her letters because they were always so encouraging and full of scriptures from the bible. I did not have anyone showing me that kind of love, the God kind.
Over the years that I had been in and out of jail I had prayed many times,especially when I was in jail. I remember every time I violated my probation I would get extradited back to the West Palm Beach County jail and there was always the same older woman coming in and teaching a bible study. She was so sweet and she spoke of freedom in Jesus. I was not sure what that really meant at the time, but I knew that I needed it. I asked Jesus to come into my heart on one of those trips. I did not see a change in me, but looking back I know that God had a plan all along. He allowed me to continue in my rebellious and selfish ways a little longer before He allowed me to be set aside in prison.
I was sent from the rehab back to the judge. He sentenced me to five years in prison but because of the guidelines back then I only had to serve eighteen months. From the time that I met Sonia I really began to seek God. By the time I was sentenced to prison I knew that God had a plan for me and I was not scared. I was ready to face my consequences and move on with my life.
God did not allow prison or my past experiences to destroy me. He took what the devil meant to destroy me and turned it around for my good. He blessed me with a beautiful family. Everything that I lost God gave me back and more. I have a wonderful husband who puts our family first. I have children who love God and that are constantly praising Him.
He can do the same for you if you will let Him. I am not proud of what I have done in my past, but if I had to go through it all over again so that I could better understand someone else's sorrow then I would. I am who I am today because of God's grace. I am His Trophy of Grace.


On a daily basis we offer a variety of fuels and oils, delivered at unbeatable prices.
We deliver Propane, Heating Oil, Kerosene, On-Road and Off-Road Diesel Fuel, Ethenol 87 & 93 Octane Gasoline and Ethenol Free 87 & 90 Octane Gasoline.
We offer Automatic, Scheduled, and Will-Call Deliveries.
Automatic delivery means that you can put your mind at ease and be assured we will deliver to you automatically according to heating degree days. This is the easiest way to assure that you do not run out of fuel. You do not need to monitor your own tank or call us for a delivery.
Scheduled delivery means that we automatically deliver to you after a pre-determined time period has elapsed. Scheduled deliveries are helpful if your use is not consistent and automatic heating degree day delivery is not an option. You do not need to monitor your tank or call us for a delivery.
Will-call delivery means that you will continue to monitor your own tank and call us when you need a delivery. With will-call, you accept responsibility for monitoring your own gauge and calling our office one week prior to your needing the fuel so that your delivery can be scheduled. If you run out of fuel and a special delivery must be made, you will incur an additional delivery fee.
Heating degree days are an indication of how cold it is on any given day and how much fuel you will require. The National Weather Service provides us with this information daily. After we fill your tank, we keep track of the degree days to ensure we deliver oil when you need it.
The easiest way to explain this concept is using your car and how it uses gasoline as an example: Your car uses gasoline as you drive. How much gas your car uses is measured in Miles Per Gallon (MPG). By knowing how many gallons your car's gasoline tank holds, and how many miles per gallon your car provides, you can estimate when you will need to refuel your tank.
Automatic delivery uses the same concept. We know how much fuel your tank holds when it is full, and we multiply it by the (Miles Per Gallon) of your house, which is known as the K-Factor. This tells us "how far" your house can go before you will need more fuel.
At Countryside Fuel and LP Gas, our goal is to go above and beyond our customers' oil heating expectations. We will always do our absolute best to deliver your order of fuel whenever you need it, regardless of the weather.
Our minimum fuel delivery at the quoted cash price is 150 gallons. We will deliver less than 150 gallons for an additional $.10 per gallon. We do not schedule deliveries for quantities less than 100 gallons. If any delivery takes less than 100 gallons, we do add a $35 delivery charge.
We are always expanding our delivery area to provide eastern Pennsylvania with the best fuel prices and the best customer service.
Our current delivery area include: Berks County, Hershey, Lebanon County, Grantville, Schuylkill County, Kutztown, Reading, Lehigh Valley, Allentown, Northampton County Harrisburg, Manheim, Ephrata and Denver. Click here for a detailed map of our service areas.


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Springfield Guard members assisting hurricane relief in Puerto Rico
Christy Curtis | 10 October, 2017, 00:31
Puerto Rico bond insurer Assured Guaranty Ltd (N:) said late on Friday it voluntarily withdrew a complaint that challenged the legality of the island's fiscal turnaround plan, citing the devastating impact of Hurricane Maria.
Assured Guaranty, along with a second insurer MBIA Inc (N:), filed their lawsuit against the island's government and a federally appointed financial oversight board on May 3, a day after Puerto Rico announced a historic restructuring of its public debt.
Responding to a tweet asking if Tesla could help, Musk answered: "The Tesla team has done this for many smaller islands around the world, but there is no scalability limit, so it can be done for Puerto Rico too".
Rossello said the government was trying to identify problems in the distribution pipeline, looking to ensure that local leaders deliver resources to people as soon as they arrive in the municipality.
Soldiers assigned to the 249th Engineer Battalion (Prime Power), along with civilian U.S. Army Corps of Engineer responders, are working with the Federal Emergency Management Agency to provide power generators to support disaster relief emergency operations throughout Puerto Rico.
The damage wreaked by Hurricane Maria in Puerto Rico in September 2017 could have serious repercussions for patients who rely on medicines and healthcare products manufactured there.
But people did not buy that anyone should thank him for the relief efforts in Puerto Rico, given that he was vacationing at a golf resort while community members and aid organizations were scrambling to save lives.
"Despite the Fake News Media in conjunction with the Dems, an incredible job is being done in Puerto Rico". While gasoline and other supplies had reached the island, the lack of roads and bridges would not allow aid workers to bring them to those parts of the island most in need, Menendez said. "We'll continue to partner with the people of Puerto Rico to help them recover, and secure their economic future".
In a joint effort with other senators, including U.S. Sen. He claimed that the people of Puerto Rico also had "fun" during his visit.
"So what we need to do is work with our colleagues to make sure we get this immediate help, make sure it is spent the right way, prioritize the spending in ways that has the most needs", said Kaine.
Church services resumed in Caonillas, Puerto Rico. "The federal government has the transportation and logistics infrastructure to help alleviate the immediate and overwhelming crisis now facing Puerto Rico and the U.S. Virgin Islands". The island left a powerful impression on me, and I hope to return to keep documenting its recovery. "They're hanging in there, but they need help".
Group to gather at Columbus statue downtown for 'Indigenous Peoples Day'
Government should pay half funs for the Delhi metro - kejiriwal
Iran warns United States against imposing new sanctions and 'terror' designation
He stressed that if new sanctions are imposed on Iran, the chance for any interaction will be lost forever. Washington says that Iran's missile program is threatening the regional and worldwide peace.
Nelly Arrested for Alleged Sexual Assault
The website reports that the hip-hop star was booked on second-degree rape charges early Saturday morning and is still in custody. He said he was "confident" in the fact that the police investigation should not lead to an indictment.
Puerto Rico raises Hurricane Maria death toll to 34
Trump visited a church in Guaynabo where he distributed supplies to hurricane victims, including rolls of paper towels. During Trump's visit to the USA territory on Tuesday, the mayor and president shook hands.
Head, legs of missing journalist found by divers
They were found not far from where Ms Wall's torso was discovered 11 days after she boarded Peter Madsen's submarine on 10 August. But police have said 15 stab wounds were on the torso found at sea off Copenhagen on August 21.
Pink Blasts Dr. Luke: 'This Is His Karma and He Earned It'
She dropped her sexual assault lawsuit in August previous year as she wanted to focus on releasing new music. Luke has denied Kesha's accusations and countersued for defamation and breach of contract.
Hart alum Trevor Bauer collects first career postseason win
Knock the Indians down once, knock them down a second time, and all they do is bounce back ready for more . He loaded the bases in each of the first two innings, but managed to hold the Indians to just three runs.
Board has three Delhi government representatives: the chief secretary, principal secretary (finance) and the transport secretary. He hoped that the spirit of partnership would continue to prevail and a mutually acceptable solution would be found.
Bigg Boss 11 Contestant Vikas Gupta jumps out of the house
Meanwhile, there are reports that Vikas" "special' friend, Priyank Sharma might be back in the Bigg Boss house. He penned down a complaint against the show as well as an actor as Salman warned him which disturbs him.
Scotland's World Cup dream over after draw against Slovenia
However, opponents Slovenia sit just two points behind and Slovakia are also lurking with just one point less. Unless you've been in that situation I don't think I've got the words to explain it to you.
Red Sox Lose Game 2 of ALDS Against Astros 8-2
The Red Sox had hoped to torment Houston's pitchers with walks, singles and doubles, then dash aggressively around the bases. Jose Altuve led off the inning with a single before Carlos Correa hit a two-run home run to give the Astros a 2-0 lead.
Fitbit, Inc. (NYSE: FIT): Analysts' Suggestions in the Limelight
According to their observations and findings, the stock could provide a high EPS of $-0.02/share and a low EPS of $-0.07/share. The company's quarterly revenue was down 39.8% on a year-over-year basis. 3247850 shares were traded on Fitbit's last session.
The Harvest Moon can be seen tonight
This year's harvest moon marks the first time since 2009 the harvest moon has arced across an October sky. The next time that we'll see a Harvest Moon in October is 2020, National Geographic notes.
California wine country wildfires torch homes Wildfires are engulfing the Napa Valley neighborhood of Calistoga, California, on October 9, 2017 . Brown issued the declaration on Monday, as multiple fires forced people to evacuate their homes.
Group to gather at Columbus statue downtown for 'Indigenous Peoples Day' Their stories didn't make the history that the winners wrote, but they too should be honored and appreciated. The states of Minnesota , Vermont and Alaska also have made it a statewide celebration.
Immigration demands linked to support for DACA Trump's list was criticized by Chuck Schumer and Nancy Pelosi, the respective Democratic leaders in the Senate and House. The White House unveiled its vision for immigration reform Sunday and said that it had sent the document to Congress.
Mike Pence walks out of National Football League game after players kneel for anthem President Donald Trump later tweeted: "I asked @VP Pence to leave stadium if any players kneeled, disrespecting our country". Trump has railed against the form of protest, calling it disrespectful to the flag and to veterans.
Jaguars-Steelers, Week 5 Chris Reed is also an important player for the offense in the game against the Steelers as the first right guard backup. It's a battle of division leaders at Ford Field this Sunday as the Lions host the Panthers in a showdown of 3-1 teams.
Crying Odell Beckham carted off the field in Giants disaster For the most part, Twitter seems to be sharing an appropriately morose and surprisingly mature response to the injury. Beckham's injury came on the same day that the Giants also lost Brandon Marshall and Sterling Shephard to injuries.
Colin Kaepernick's Girlfriend Nessa Diab Denies QB Will Stand for Anthem With the news that he plans to stand for the American national anthem, that return could be sooner rather than later. This post originally published at 10:26 a.m. "He's just looking for an opportunity", said La Canfora.
Final JUSTICE LEAGUE Trailer Teases Superman's Return Simmons, Diane Lane , Jeremy Irons , Connie Nielsen , Amber Heard , and Willem Dafoe , Justice League opens on November 17, 2017 . Is the Lois & Clark Scene in the Justice League Trailer Real or a Dream? The Kryptonian died at the end of " Batman v.
Japanese Grand Prix: Sebastian Vettel reprimanded for anthem absence That said, Vettel's odds remain unfavorable, even if Hamilton is sidelined by mechanical problems of his own. He first lost a place to Max Verstappen at the hairpin and then Esteban Ocon, before falling down the field.
For that much-needed awareness on breast cancer Smoking, especially for those women who smoke before their first pregnancy, is thought to increase the risk of breast cancer. The tour is for everyone, whether you are in treatment, a survivor or looking for breast cancer prevention advice.
Iowa State QB Jacob Park not with team in Oklahoma Park, a junior, struggled in his most recent outing - being intercepted three times in Iowa State's 17-7 loss to Texas. Iowa State will be without starting quarterback Jacob Park when the Cyclones face No. 3 Oklahoma on Saturday morning.
Diwali has come early due to changes in GST rules: PM Modi Modi will lay the foundation for the construction of Cable Stayed Signature Bridge between Beyt Dwarka and Okha on NH-51. The Prime Minister said that the world's attention is being drawn to India, and people are coming to invest here.
Selected as NLDS Game 4 starter If the Dodgers could have chosen one team to avoid in the postseason it probably would have been the Arizona Diamondbacks . But if Ray (15-5, 2.89 in 28 starts this year) is feeling as good as he said he is, it's bad news for the Dodgers.
Large Internet-Beaming Balloons Might Be Headed To Puerto Rico It's unclear if Puerto Rico's stressed telecom companies even have the resources to partner with Google on this endeavor. Aid workers are pairing Vanu's devices with other technology, such as inflatable satellite antennas.
SC cites adverse IB reports to reject 3 HC judge-aspirants The Supreme Court said it was conscious that it had earlier upheld the validity of carrying out the death sentence by hanging. Section 354 of the CrPC provides for execution of death sentence by hanging.
Some Republicans open to banning "bump stocks" after Las Vegas shooting
Sasikala out of jail but can't have political meetings, media interactions
Isis claims Las Vegas shooting: What have they said?
Tillerson calls NBC News report on his resignation 'erroneous'


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   * @param {String} [config.modPrefix] - Modifier prefix (default: '_')
   * @param {String} [config.modDlmtr] - Modifier delimiter (default: '_')
   * @param {String} [config.namePattern] -
   *   Pattern to match valid block names (default: '[a-zA-Z0-9-]+')
   */
  BEM.prototype.setConfig = function(config) {
    this.config = $.extend({}, {
      namePattern: '[a-zA-Z0-9-]+',
      elemPrefix: '__',
      modPrefix: '_',
      modDlmtr: '_'
    }, config);

    this.blockClassRe = this.buildBlockClassRe();
    this.elemClassRe = this.buildElemClassRe();
    this.modClassRe = this.buildModClassRe();
  };

  /**
   * Get parent block of element.
   * @public
   *
   * @param {Object} $this
   * @return {Object}
   */
  BEM.prototype.getBlock = function($this) {
    var blockClass = this.getBlockClass($this)
      , block = $this.closest('.' + blockClass);

    block.selector = blockClass;
    return block;
  };

  /**
   * Switch block context.
   * @public
   *
   * @param {Object} $this
   * @param {String} block
   * @param {String} [elem]
   * @return {Object}
   */
  BEM.prototype.switchBlock = function($this, block, elem) {
    var elem = elem || null;

    elem
      ? $this.selector = this.buildSelector({ block: block, elem: elem })
      : $this.selector = this.buildSelector({ block: block });

    return $this;
  };

  /**
   * Find element in block.
   * @public
   *
   * @param  {Object}  $this    DOM element
   * @param  {String}  elemKey  Element name
   * @return {Object}
   */
  BEM.prototype.findElem = function($this, elemKey) {
    var blockClass = this.getBlockClass($this)
      , elemSelector = '.' + this.buildElemClass(blockClass, elemKey)
      , elem = $this.is(elemSelector) ? $this : $this.find(elemSelector);

    return elem;
  };

  /**
   * Get value of modifier.
   * @public
   *
   * @param {Object} $this
   * @param {String} modKey
   * @return {String}
   */
  BEM.prototype.getMod = function($this, modKey) {
    var mods = this.extractMods($this.first());

    if (mods[modKey] != undefined) return mods[modKey];
    return null;
  };

  /**
   * Check modifier of element.
   * @public
   *
   * @param {Object} $this
   * @param {String} modKey
   * @param {String} [modVal]
   * @return {Boolean}
   */
  BEM.prototype.hasMod = function($this, modKey, modVal) {
    var mods = this.extractMods($this.first());

    if (modVal) {
      if (mods[modKey] == modVal) return true;
    }
    else {
      if (mods[modKey]) return true;
    }

    return false;
  };

  /**
   * Set modifier on element.
   * @public
   *
   * @param {Object} $this
   * @param {String} modKey
   * @param {String} [modVal]
   * @param {Object}
   */
  BEM.prototype.setMod = function($this, modKey, modVal) {
    var self = this
      , selector = $this.selector;

    $this.each(function() {
      var current = $(this);
      current.selector = selector;

      var mods = self.extractMods(current)
        , baseName = self.getBaseClass(current);

      if (mods[modKey] != undefined) {
        var oldModName = self.buildModClass(baseName, modKey, mods[modKey]);
        current.removeClass(oldModName);
      }

      if (modVal !== false) {
        var newModName = self.buildModClass(baseName, modKey, modVal);
      }

      current
        .addClass(newModName)
        .trigger('setmod', [modKey, modVal]);
    });

    return $this;
  };

  /**
   * Delete modifier on element.
   * @public
   *
   * @param {Object} $this
   * @param {String} modKey
   * @param {String} [modVal]
   * @param {Object}
   */
  BEM.prototype.delMod = function($this, modKey, modVal) {
    var self = this
      , selector = $this.selector;

    $this.each(function() {
      var current = $(this);
      current.selector = selector;

      var mods = self.extractMods(current)
        , baseName = self.getBaseClass(current);

      if (modVal) {
        if (mods[modKey] == modVal) {
          var modName = self.buildModClass(baseName, modKey, mods[modKey]);
        }
      }
      else {
        var modName = self.buildModClass(baseName, modKey, mods[modKey]);
      }

      current
        .removeClass(modName)
        .trigger('delmod', [modKey, modVal]);
    });

    return $this;
  };

  /**
   * Filtering elements by modifier.
   * @public
   *
   * @param {Object} $this
   * @param {String} modKey
   * @param {String} [modVal]
   * @param {Boolean} [inverse]
   * @return {Object}
   */
  BEM.prototype.byMod = function($this, modKey, modVal, inverse) {
    var self = this
      , modVal = modVal || null
      , inverse = inverse || false
      , selector = $this.selector
      , result = $();

    $this.each(function() {
      var current = $(this);
      current.selector = selector;

      var mods = self.extractMods(current)
        , baseName = self.getBaseClass(current);

      if (modVal) {
        if (mods[modKey] == modVal) {
          var modName = self.buildModClass(baseName, modKey, mods[modKey]);
        }
      }
      else {
        if (mods[modKey] != undefined) {
          var modName = self.buildModClass(baseName, modKey, mods[modKey]);
        }
      }

      result = result.add(inverse
        ? current.not('.' + modName)
        : current.filter('.' + modName));
    });

    result.selector = selector;
    return result;
  };

  /**
   * Get block names from element.
   * @protected
   *
   * @param {Object|String} $this
   * @return {Object}
   */
  BEM.prototype.extractBlocks = function($this) {
    var self = this, result = []
      , selectors = this.getClasses($this);

    $.each(selectors, function(i, sel) {
      var type = self.getClassType(sel);

      if (type == 'block') {
        result.push(sel);
      }
      else if (type == 'elem') {
        var elem = sel.split(self.config.elemPrefix);
        result.push(elem[0]);
      }
    });

    return result;
  };

  /**
   * Get element names from element.
   * @protected
   *
   * @param {Object} $this
   * @return {Object}
   */
  BEM.prototype.extractElems = function($this) {
    var self = this, result = [];

    $.each(self.getClasses($this), function(i, className) {
      if (self.getClassType(className) == 'elem') {
        var elemName = className.split(self.config.elemPrefix);
        result.push(elemName[1]);
      }
    });

    return result;
  };

  /**
   * Get modifiers from element.
   * @protected
   *
   * @param {Object} $this
   * @return {Object}
   */
  BEM.prototype.extractMods = function($this) {
    var self = this, result = {};

    $this.each(function() {
      var $this = $(this);

      $.each(self.getClasses($this), function(i, className) {
        if (self.getClassType(className) == 'mod') {
          var re = self.buildModClassRe().exec(className);
          var modName = re[1].split(self.config.modDlmtr);

          if (modName[1] !== undefined && modName[1] !== false) {
            var modVal = modName[1];
          } else {
            var modVal = true;
          }

          result[ modName[0] ] = modVal;
        }
      });
    });

    return result;
  };

  /**
   * Get classes names from element.
   * @protected
   *
   * @param {Object} $this
   * @return {Object}
   */
  BEM.prototype.getClasses = function($this) {
    var classes, result = [];

    if (typeof $this == 'object') {

      if ($this.selector.indexOf('.') === 0) {
        classes = $this.selector.split('.');
      }
      else if ($this.attr('class') != undefined) {
        classes = $this.attr('class').split(' ');
      }
      else {
        return null;
      }

    }
    else {
      classes = $this.split('.');
    }

    $.each(classes, function(i, className) {
      if (className != '') result.push($.trim(className));
    });

    return result;
  };

  /**
   * Build regexp for blocks.
   * @protected
   *
   * @return {RegExp}
   */
  BEM.prototype.buildBlockClassRe = function() {
    return new RegExp(
      '^(' + this.config.namePattern + ')$'
    );
  };

  /**
   * Build regexp for elements.
   * @protected
   *
   * @return {RegExp}
   */
  BEM.prototype.buildElemClassRe = function() {
    return new RegExp(
      '^' + this.config.namePattern + this.config.elemPrefix + '(' + this.config.namePattern + ')$'
    );
  };

  /**
   * Build regexp for modifiers.
   * @protected
   *
   * @return {RegExp}
   */
  BEM.prototype.buildModClassRe = function() {
    return new RegExp(
      '^(?:' + this.config.namePattern + '|' + this.config.namePattern + this.config.elemPrefix + this.config.namePattern + ')' + this.config.modPrefix + '(' + this.config.namePattern + '((' + this.config.modDlmtr + this.config.namePattern + ')$|$))'
    );
  };

  /**
   * Build class name for block.
   * @protected
   *
   * @param {String} blockName
   * @return {String}
   */
  BEM.prototype.buildBlockClass = function(blockName) {
    return blockName;
  };

  /**
   * Build class name for element.
   * @protected
   *
   * @param {String} blockName
   * @param {String} elemKey
   * @return {String}
   */
  BEM.prototype.buildElemClass = function(blockName, elemKey) {
    return blockName + this.config.elemPrefix + elemKey;
  };

  /**
   * Build class name for modifier.
   * @protected
   *
   * @param {String} blockName
   * @param {String} modKey
   * @param {String} modVal
   * @return {String}
   */
  BEM.prototype.buildModClass = function(baseClass, modKey, modVal) {
    if (modVal !== undefined && modVal !== true) {
      return baseClass + this.config.modPrefix + modKey + this.config.modDlmtr + modVal;
    } else {
      return baseClass + this.config.modPrefix + modKey;
    }
  };

  /**
   * Build selector from object or string.
   * @private
   *
   * @param {String|Object}
   * @param {String}
   * @return {String}
   */
  BEM.prototype.buildSelector = function(selector, prefix) {
    if (prefix !== '') {
      var prefix = prefix || '.';
    }

    if (typeof selector == 'object') {
      if (selector.block != undefined) {
        var buildSelector = this.buildBlockClass(selector.block);

        if (selector.elem != undefined) {
          buildSelector = this.buildElemClass(buildSelector, selector.elem);
        }

        if (selector.mod != undefined) {
          var mod = selector.mod.split(':');
          buildSelector = this.buildModClass(buildSelector, mod[0], mod[1]);
        }
      }
    }

    return buildSelector != undefined
      ? prefix + buildSelector
      : prefix + selector;
  };

  /**
   * Build class name for block.
   * @protected
   *
   * @param {Object|String} $this
   * @param {Number} [index]
   * @return {String}
   */
  BEM.prototype.getBlockClass = function($this, index) {
    var blockClasses = this.extractBlocks($this);
    var index = index || 0;

    return index <= blockClasses.length - 1
      ? blockClasses[index]
      : null;
  };

  /**
   * Get base class from element.
   * @protected
   *
   * @param {Object} $this
   * @return {String}
   */
  BEM.prototype.getBaseClass = function($this) {
    var self = this, baseClass = null;
    var selectors = this.getClasses($this);

    $.each(selectors, function(i, sel) {
      var classType = self.getClassType(sel);

      if (classType && classType != 'mod') {
        baseClass = sel;
      }
    });

    return baseClass;
  };

  /**
   * Get class type.
   * @protected
   *
   * @param {String} className
   * @return {String}
   */
  BEM.prototype.getClassType = function(className) {
    if (this.modClassRe.test(className)) {
      return 'mod';
    }
    else if (this.elemClassRe.test(className)) {
      return 'elem';
    }
    else if (this.blockClassRe.test(className)) {
      return 'block';
    }
    return null;
  };

  /**
   * Create BEM instance.
   */
  $.BEM = new BEM();

  /**
   * Extend jQuery object.
   */
  $.fn.extend({
    block: function() {
      return $.BEM.getBlock(this);
    },

    elem: function(ctx, elemKey) {
      if (!elemKey) {
        elemKey = ctx;
        ctx = null;
      }

      return $.BEM.findElem(ctx || this, elemKey);
    },

    ctx: function(block, elem) {
      return $.BEM.switchBlock(this, block, elem);
    },

    mod: function(modKey, modVal) {
      if (typeof modVal == 'undefined') {
        modVal = null;
      }

      if (modVal === false) {
        return $.BEM.delMod(this, modKey);
      }

      return (modVal != null)
        ? $.BEM.setMod(this, modKey, modVal)
        : $.BEM.getMod(this, modKey);
    },

    setMod: function(modKey, modVal) {
      return $.BEM.setMod(this, modKey, modVal);
    },

    delMod: function(modKey, modVal) {
      return $.BEM.delMod(this, modKey, modVal);
    },

    hasMod: function(modKey, modVal) {
      return $.BEM.hasMod(this, modKey, modVal);
    },

    byMod: function(modKey, modVal) {
      return $.BEM.byMod(this, modKey, modVal);
    },

    byNotMod: function(modKey, modVal) {
      return $.BEM.byMod(this, modKey, modVal, 'inverse');
    },

    /**
     * Toggle blocks's or elem's modifier `modKey` between `modVal1` and `modVal2`
     * @param {String} modKey
     * @param {String} modVal1
     * @param {String} modVal2
     * @return {*}
     */
    toggleMod: function (modKey, modVal1, modVal2) {
      if (this.hasMod(modKey, modVal1)) {
        return this
            .delMod(modKey, modVal1)
            .setMod(modKey, modVal2);
      } else {
        return this
            .delMod(modKey, modVal2)
            .setMod(modKey, modVal1);
      }
    }
  });

}));

redpajama_set_name: RedPajamaGithub


The number of people signing up for private insurance coverage under the Affordable Care Act has now reached eight million. While primarily symbolic, it does represent a victory after initial projections of seven million were reduced to six million due to the problems when the exchanges opened. We know that if they failed to meet these projections, Republicans would be making a big deal of them. In addition, late enrollees included a high percentage of young people.
Good news means more positive head lines, such as National Journal writing that Obamacare is on a Winning Streak. The political climate is changing, with some Democrats now being more willing to run on its success. I think it is essential that they do this to reduce the risk of the loss of a large number of seats this November. The evidence shows that Obamacare is a success but if Democrats don't defend it, voters will only hear Republican attacks. Hiding from Obamacare will only make Democrats look weaker, and will not protect them from voters who vote against Democrats based upon Republican misinformation.
Republicans used to talk about Bush Derangement Syndrome. Washington Post columnist Charles Krauthammer defined it as "the acute onset of paranoia in otherwise normal people in reaction to the policies, the presidency — nay — the very existence of George W. Bush." Republicans like Krauthammer understood that BDS helped the Bush administration in two ways: it fired up their supporters and it distracted liberals from more modest, but effective, critiques.
But it's coming at a moment when Obamacare's successes are getting tougher and tougher to deny. The law signed up more than 7.5 million people in the exchanges, more than 3.5 million people in Medicaid, and it led millions more to get health care through their employers or directly through insurers. Premiums are lower than the Congressional Budget Office predicted when the law passed, and insurers are already thinking about how to compete for applicants in 2015. The White House has a much better story to tell than anyone — including me — thought possible in December.
For Republican pundits it might not matter that Obamacare is a success. Republicans show more intensity in their views, and very little concern for the truth. Campaigning against Obamacare might still motivate Republicans to get out and vote.
That's mainly because of renewed confidence and support from previously demoralized Democrats. But it's also a reflection, it seems to me, of the political vulnerability of Republicans who have failed to present a viable alternative to the law, and indeed seem set, in the eyes of most voters, merely to repeal ACA provisions that are individually popular. And this bad position is very likely to endure because of the intensity of the loathing for Obama/Obamacare among the Medicare recipients in the GOP base. It seems to me that right now, the GOP cannot offer an alternative that keeps the more popular parts of Obamacare without the air fast leaking out of their mid-term election balloon. And so by the fall, the political dynamics of this may shift some more in Obama's direction. By 2016, that could be even more dramatic. One party – the GOP – will be offering unnerving change back to the status quo ante, and the other will be proposing incremental reform of the ACA. The only thing more likely to propel Hillary Clinton's candidacy would be a Republican House and Senate next January.
It's that long game thing again, isn't it? Like the civil rights revolution of the Obama years, it seemed a close-to-impossible effort to start with, and then was gradually, skillfully ground out. It also seems true to me that the non-event of the ACA for many, many people will likely undermine some of the hysteria on the right. The ACA-opponents may be in danger of seeming to cry wolf over something that isn't that big a deal. Yes, they may have premium hikes to tout as evidence of the alleged disaster. And every single piece of bad news on the healthcare front will be attributed to the ACA, fairly or not. But the public will still want to know how premiums can go down without people with pre-existing conditions being kicked out of the system, or without kids being kicked off their parents' plan, and so on. I think, in other words, that the GOP's position made a lot of short-term political sense in 2010 and even 2012. But it's a much tougher sell in 2014, let alone 2016. Once again, they have substituted tactics for strategy. Every time they have done that with Obama, they have failed.


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If there is no change in supply of U.S. dollars, but there is an increase in demand, there will be an increase in the rise of exchange rate. Similarly, if there is no change in supply of U.S. dollars, but there is a decrease in demand for it, there will be a drop in exchange rate.
Again, if there is no change in demand related to U.S. dollars, but there is a decrease in supply, there will be a hike in exchange rate. In the same way, if there is no change in demand related to U.S. dollars, but there is an increase in supply of it, there will be a drop in exchange rate.
It can be stated that such forecast is similar if compared with any other type of market.


text:
Cincinnati Children's Hospital Medical Center Raises Awareness about National Poison Prevention Week | 2015
National Poison Prevention Week Kicks Off
Cincinnati Children's Raises Awareness About Poison Prevention
Every 10 seconds a call is made to a poison center in the U.S.
Drug overdoses are the leading cause of unintentional deaths outnumbering car accidents and firearms both locally and nationally. A focal point for prevention and treatment of these exposures is the Drug and Poison Information Center (DPIC) at Cincinnati Children's Hospital Medical Center. Health professionals are available to answer your call 24 hours a day, 7 days a week at 1-800-222-1222.
In 2014, DPIC received more than 81,000 calls regarding issues that were addressed by the center's trained staff, which includes doctors, nurses and pharmacists. The Drug and Poison Center is one of the largest in the country and provides service to 24 counties in Southwest Ohio and Northeast Ohio.
"Of course the best way to treat a poisoning is to prevent it from occurring in the first place," said Earl Siegel, DPIC managing director. "Poison centers can assist with awareness, caution and safety around drugs and chemicals."
Nationwide, more than three million poisonings are reported each year to poison centers. According to the American Association of Poison Control Centers, just under half of all exposure cases managed by poison centers involved children younger than six. The majority occurred in adolescents and adults.
The U.S. Department of Health and Human Services gives the following tips for preventing poisoning:
Keep chemicals in their original bottles or containers. Do not use food containers such as cups, bottles, or jars to store chemicals such as cleaning solutions or beauty products.
Keep all drugs in medicine cabinets or other childproof cabinets that young children cannot reach.
Never leave children alone with household products or drugs. If you are using chemical products or taking medicine and you have to do something else, such as answer the phone, take any young children with you.
Turn on fans and open windows when using chemicals or household cleaners, and never sniff containers to see what is inside.
Never share or sell your prescription drugs.
Wear protective clothing (gloves, long sleeves, pants, socks, shoes) if you spray pesticides or other chemicals. Stay away from these areas until the spray has dried or for at least one hour.
Never mix household or chemical products together. Doing so can create a dangerous gas.
National Poison Prevention Week begins on Sunday, March 15, and continues through Saturday, March 21. You can call 1-800-222-1222 anywhere in the United States and it immediately connects the caller with the appropriate poison control center for their location. Post it somewhere in your home where others will see it and program it in your home and mobile phones.
About National Poison Prevention Week
Since 1962, the President of the United States has proclaimed the third week of March as National Poison Prevention Week to focus national attention on the dangers of poisonings and how to prevent them. To learn more about ways to keep people of all ages safe and help prevent poisonings, visit the Poison Help Web site at www.PoisonHelp.hrsa.gov or www.poisonprevention.org.
About Cincinnati Children's
Cincinnati Children's Hospital Medical Center ranks third in the nation among all Honor Roll hospitals in U.S. News & World Report's 2014 Best Children's Hospitals. It is also ranked in the top 10 for all 10 pediatric specialties. Cincinnati Children's, a non-profit organization, is one of the top three recipients of pediatric research grants from the National Institutes of Health, and a research and teaching affiliate of the University of Cincinnati College of Medicine. The medical center is internationally recognized for improving child health and transforming delivery of care through fully integrated, globally recognized research, education and innovation. Additional information can be found at www.cincinnatichildrens.org. Connect on the Cincinnati Children's blog, via Facebook and on Twitter.
Shannon Kettler, 513-636-5218, shannon.kettler@cchmc.org


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In my twenties, I would never have slept with a married man. I'm too moralistic. The granddaughter of a preacher. But now, I don't consider it a moral failing. it just IS. I see him, despite his marital status. I love him, despite his marital status. I caress him in my bed, despite his marital status.
It's not the big bad city that changed me. I'm still the goody-two-shoes Wisconsin girl. It's just getting older. It means the stripping the body and mind clean of what constricts us, the old black and white thinking, and embracing complexity. Don't overthink it. See the world with an open mind. We are all flawed. Brene Brown tells me to not feel shame. My love for him is not shameful. Yes, our relationship is complicated, like they say on Facebook. But I understand it. I understand that he has kids, and his wife who's crazy, so he needs more time. What I can give him is patience. I can wait. That's true love. Like in Shakespeare.
He treats me well, better than any other man. He brings me gifts and tells me I'm beautiful. I so want to meet his kids. Some day. And we will be a family. Or else, we can have our own kids. Yeah, imagine that! What am I talking about? I'm not going to turn into my sister, stuck at home with kids, getting fatter by the day. No kids right now! That time will come. Just enjoy what you have. With no shame. Thank you, Brene Brown.
I bought a steak for tonight. He loves steak. I wish we would skip dinner completely and fall into bed, so I can feel his strong hands grab me from behind. I love when he says my name. I wait for that. He says that I make him feel like a man again. That his wife is aloof and makes him feel that he never makes enough money.
It's 7:30. He said he would meet me here a half hour ago. But it's OK. He must be stuck somewhere. I know Tuesday night his daughters have Girl Scouts. I wish he would text and tell me where he is. He needs to be discreet. I understand that. Until he can divorce her, it has to be this way. It's all good. What can I do? All I can to do now is wait. True love requires patience.
It's only like this in the movies. In real life, it's far more (and less) complicated.


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Volkswagen has revealed the newest member of the ID. Family – the ID. ROOMZZ – at the Auto Shanghai 2019. The multivariable all-rounder is a zero-emission SUV of the five-meter class which is tailored to both family and business requirements. The series version is to be initially launched on the Chinese market in 2021. The ID. ROOMZZ's bodywork design follows the clear, homogeneous lines of the rest of the ID. family. The concept car also breaks new ground in the full-size SUV segment thanks to multiple details.
"This SUV is a monolith, appearing to be seamlessly machined from one solid block. The battery-powered ID. ROOMZZ moves effortlessly – silently and without emissions," says Klaus Bischoff, chief designer at the Volkswagen brand.
The ID. ROOMZZ combines future IQ.DRIVE systems – on request it can glide fully automatically (Level 4) through the traffic in ID. Pilot mode. The vehicle occupants are provided with information via interactive light zones. The completely new variable interior concept can be individualized to a great extent. Various seating configurations can be adapted not only to passengers' personal wishes, but also to the respective driving mode.
The ID. ROOMZZ is not fitted with a conventional dash panel. In the manual "ID. Drive" mode, the digital cockpit along with the steering wheel appears to hover in front of the driver. The digital cockpit consists of a full glass- front panel. The digitalized steering wheel has been conceptually integrated into the panel.
The materials used in the interior are also unusual. The seat covers, for example, are made of AppleSkinTM – a new product that consists of a renewable raw material. Specially processed wooden veneers are also used in the "ID. Light" areas of the door panels. The CleanAir system uses an active filter system to ensure that the air in the vehicle interior remains clean even if the ambient air isn't.