The Nine Mile Run Watershed Association (NMRWA) is honored to announce that Larry Patchel was selected as a Codeine and promethazine syrup uk. This award highlights inspirational volunteers in action who have made a contribution to urban forestry by improving community trees and the neighborhoods where they live.
Larry stands with a Chestnut tree he planted.
Emulsion gel nifedipine uk is a national nonprofit organization dedicated to improving the health and livability of cities by planting and caring for trees. To date, over 5 million volunteers from ACTrees member organizations (including NMRWA) have planted more than 15 million trees across the country.
NMRWA nominated Larry for this award because he is a truly exceptional volunteer that encourages people from different backgrounds and groups to work together as a community. Larry uses his charm and vast horticultural knowledge and experience to teach others about proper tree planting and pruning techniques, soil composition, plant taxonomy, proper tool usage, and safety.
Whether he is identifying poison ivy for kids at the high school rain garden, digging tree holes with students from the Western Pennsylvania School for the Deaf, or advocating for trees at the Boys and Girls Club of Wilkinsburg, Larry's hands-on, contagious, and charismatic style is well-known in this small Pittsburgh community.
Larry is an active member of the American Chestnut Foundation, helping to hybridize Chinese and American chestnuts, and tending to the seedlings until they become trees. He sets up a tent each year at the Phipps Conservatory Plant Sale and sharpens pruners and other tools to benefit the Men's Garden Club of Pittsburgh, of which he is a member. He also attended all of the tree plantings from the 500 Tree Initiative in Wilkinsburg implemented by NMRWA.
Brenda Smith, Executive Director of Nine Mile Run Watershed Association says, "We are very lucky to have Larry as a dedicated and passionate volunteer of Nine Mile Run Watershed Association. He continues to work hard to improve his community. Larry embodies ACTrees' mission of 'improving the environment and community – one tree at a time'. We are excited to acknowledge Larry's dedication and hard work through the ACTrees Volunteer of the Year nomination".
We want to thank Larry for his dedication to and passion for our work.
Larry stands with an oak tree, one of the largest oldest trees in the borough of Wilkinsburg.
Check out Clomid for sale canada' announcement about their new and improved rain container design below. They need your help naming it, so put your thinking caps on & you could win one for free!
From now until Friday, March 28th, Levitra 10mg preis ohne rezept is soliciting help from creative minds around Pittsburgh to help us come up with a name for our new rain container! The winning selection will receive a free StormWorks property consultation, one 116 gallon 'still-to-be-named' rain container, and free delivery/installation! All contest entries must be received through Twitter, Facebook, or email.
Today's blog post comes from the Drugstore shipping to uk –Â an education & advocacy program designed to raise awareness of the stormwater runoff and sewage overflow issues in Allegheny County. NMRWA is one of the CRC's six founding organizations.
These signs, which designate areas where sewage overflows can occur, are easy to find along Pittsburgh's waterways. This one is on the South Side, adjacent to the public boat ramp next to the Birmingham Bridge.
Two years ago, the Clean Rivers Campaign launched an advocacy campaign to educate our elected officials and the public about the opportunity to create a sustainable and vibrant Pittsburgh by investing in a green first approach to solving our stormwater runoff and sewer overflow problems.
The response has been incredible – Pittsburghers recognize it's good for families, workers, and the environment to maximize our largest ever public investment to stop water pollution AND solve multiple community needs at the same time.
Rain gardens, like this one in front of the Edgewood train station, are one type of green solution that can be used to help curb sewer overflows in Pittsburgh.
Lamisilate achat, and we now have a real opportunity to build a "green first" plan for the Pittsburgh region that maximizes investment in green solutions, reinvests in neighborhoods, and creates family sustaining jobs. THEN we can looks to what complimentary gray strategies are needed to meet full water quality compliance.
But our work is far from over. Just recently, ALCOSAN reported that the Department of Justice (who serves as the legal representative for the EPA) has indicated a willingness to renegotiate the Consent Decree and to reach a new agreement by April—a very short window of opportunity!
We know that EPA officials have been flexible in allowing other cities to prioritize green solutions. But, Buy cialis online germany and to make large-scale green solutions a reality, we need visionary leadership at ALCOSAN. We also need compelling local data to guide implementation, and sustained public pressure to hold ALCOSAN accountable.
These three critical pieces stand between the choice to bury billions of public dollars under our rivers or to invest that money in ways that will create clean water, healthy communities, and economic opportunities for generations to come.
We need your help. And we need to act fast.
More than 175 people came out to our campaign launch during Summer 2012. We asked the EPA to let us prioritize green solutions, and all our hard work is starting to pay off! Thank you!
You stood with us at ALCOSAN public hearings and Beyond Tunnel Vision presentations. We need you to stand with us now as we keep up the pressure, educate our policy makers, and hold our leaders accountable to building a sustainable and equitable green-first sewer plan.
We also need your help to raise funds for something no one else has done—a study demonstrating the water quality improvements and community benefits that could result in from a green-first investment in the Pittsburgh region. This information will help leaders and advocates make the case for a "green first" plan.
We are calling on our supporters—you—to show your support for green solutions, bycontributing what you can to make the study happen.
Did you know that the Generika propecia bestellen, which is Pittsburgh's only member-owned natural and organic food market, is located in the Nine Mile Run Watershed? You can often find NMRWA staff there during lunch – we love their salad bar and hot food selection, not to mention the delicious drinks and snacks that are also available.
NMRWA has partnered with the EEFC many times in the past, and we really appreciate that part of their mission is to support environmental responsibility and their community. One way they accomplish this goal is through their Xenical prices australia. This program allows customers to choose to round-up their bill to the nearest dollar, with that rounded-up amount benefiting a local organization. The EEFC selects a new organization each month, and NMRWA was honored to be chosen as the recipient for January 2014!
Employees from NMRWA represented the organization at EEFC almost every weekend in January to tell people about our work – maybe you saw us there? We heard from many patrons that they have been long supporters of NMRWA and planned to "round-up" that day. Thank you to them, and to EEFC for their support and selection of NMRWA as the Round-up Recipient!
We are excited to announce that we received more than $730 from the Co-op that was raised during January – proof that small donations really do add up! We are looking forward to continued partnership with them, and are so thankful for all of our supporters who continue to help us conserve and protect the Nine Mile Run watershed.
The old Nine Mile Run Watershed Association website is a thing of the past!
Thanks to hours of hard work by NMRWA staff and some very talented designers we worked with last fall at Sell prozac online, we have updated our site with a new, mobile & tablet-friendly design, better organization, and new features – like this blog & an easier process to register for events.
We will be continuing to add content and information in the coming months, but please take a look around and let us know what you think – we hope you like it!
Also, make sure you've liked us on Cost of neurontin and Coupon for amlodipine-benazepril, and consider subscribing to our blog – these are the best ways to stay up to date on what NMRWA is working on and has to offer.
We hope to see you in the watershed soon!
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Q: Faster Jquery dropdown menu code? I have made the following ul menu with jQuery code and want to know if it the jQuery code can be made faster and/or more efficient. I'm using the hoverintend plugin for the delay in the dropdown on mouseover. So I do not want to make the menu's drop faster but only the Jquery code more efficient if it is possible.
Update:
Ok I cleaned the css/jQuery code some more. Ditching the hover function thanks to Sime Vidas. But I still wonder if the jQuery code can be made more efficient. It menu code works chrome, FF and IE8. So people can use it for their own projects.
The HTML example:

 Home

option 1

option 2

option 3

option 4

Testmenu

option 1

option 2

option 3

option 4

option 5

option 6

option 7

Empty menu

jQuery Code:
var $DropdownMenu = $("#topmenu1");
var $DivSubNav= $DropdownMenu.find(".subnav");
var $MenuHover= $DivSubNav.find("li");

$DropdownMenu.find(".menuchild ul").parent().append("∨");
$DropdownMenu.find("ul.mselected").parents("li").children("a").addClass("childselected");
$DivSubNav.each(function () {
    $(this).parent().eq(0).hoverIntent({
        timeout: 100,over: function () {
            var current = $(".subnav:eq(0)", this);current.slideDown(100);
        },out: function () {
            var current = $(".subnav:eq(0)", this);current.slideUp(200);
        }
    });
});

Style code:
#top_navbar{
position:absolute;
z-index:3000;
top:93px;
left:15px;
width:865px;
margin:0;
padding:0;
background-image:none;
background-color:#f9f9f9;
border:2px solid #dfdfdf;
height:26px;
-moz-border-radius:5px;
-webkit-border-radius:5px;
border-radius:5px;
}

/* DROP DOWN MENU */
#topmenu1{
list-style:none;
padding:0;
margin:0;
float:left;
font-size:12pt;
border:0 solid red;
background:transparent;
}

#topmenu1 li{
float:left;
margin:0;
padding:0 5px 0 5px;
position:relative;
margin-left:4px;
border-right:0 solid #EFEFEF;
cursor:pointer;
}

#topmenu1 li a{
padding: 2px;
color: #223147;
display:block;
text-decoration: none;
float: left;
cursor:pointer;
font-size:12pt;
}

#topmenu1 li a:hover{
color:#0aaafd;
}

#topmenu1 .has_child{
width: 10px;
height: 24px;
float: left;
background-image: url(/images/menu/arrow_down_blue2.gif); /* down arrow image */
background-repeat:no-repeat;
background-position:center;
border:0 solid red;
padding-left:3px;
}

#topmenu1 .subnav {
list-style: none;
position: absolute; /* Keeps subnav from affecting main navigation flow */
left: -1px; top: 26px;
margin: 0; padding: 0;
display:none;
float: left;
border: 2px solid #cfcfcf;
border-top:2px solid #fafafa;
z-index:20000;
width:190px;
background-color:#f9f9f9;
border-radius: 0px 0px 5px 5px;
-moz-border-radius-bottomleft:5px;
-moz-border-radius-bottomright:5px;
-webkit-border-bottom-left-radius:5px;
-webkit-border-bottom-right-radius:5px;
}

#topmenu1 .subnav li{
margin: 0; padding: 0;
clear: both;
background-color:transparent;
border:0 solid green;
width:190px;
position:relative;
}

html #topmenu1 .subnav li a {
padding:0;
display:block;
font-size:11pt;
width:inherit;
text-align:left;
color:#223147;
cursor:pointer;
width:100%;
}

html #topmenu1 .subnav li a span{
padding-left:10px;
}

/* Hover effect for subnav links */
html #topmenu1 .subnav li a:hover {
color:#fff;
background-color:#0aaafd;
border:0 solid red;
margin-right:-5px;
}

/* Hover effect for subnav links */
#topmenu1 .mselected span{
color:#0aaafd;
}

#topmenu1 .subnav .mselected a:hover span{
color:#FFF;
}
#topmenu1 .childselected span{
color:#0aaafd;
}

A: Tho hover part can be optimized:
$MenuHover.hover(function () {
    var c = $(this).hasClass('mselected') ? '#acb3ba' : '#0aaafd';
    $(this).stop(true).css({'background-color':c,'cursor':'pointer'}).children('a').css({'color':'#fff'});
}, function () {
    $(this).stop(true).css({'background-color':'transparent'}).children('a').css({'color':'#223147'});
});

redpajama_set_name: RedPajamaStackExchange


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As a cornerstone of the Rockford, Ill,, community, the main branch of the Rockford Public Library will soon embark on a$33 million redevelopment project. Along the Rock River in the downtown district, the original Andrew Carnegie building sits on the former site of Rockford Gas, Light and Coke, a manufactured gas plant that operated from 1856 to 1898.
At the turn of the 20th century, the gas plant was demolished and the Carnegie library was built, opening to the public in 1903. In the 1960s, the library was remodeled into the 88,000–square–foot building it is today.
During the 1960s, Commonwealth Edison acquired Rockford Gas, Light and Coke. The utility was proactive in 2010 when it decided to conduct an environmental study at the library, where its predecessor once operated. ComEd, in cooperation with the Illinois Environmental Protection Agency (IEPA) as part of the Site Remediation Program (SRP), identified manufactured gas plant residues in the soil and groundwater under the library building. They also found two of the gas holders from the original plant.
After considerable negotiation, ComEd and the library crafted an access agreement, allowing the utility to remediate the site. The library will be demolished and MGP residues will be excavated. A library will be built on the site once the cleanup is completed. The library will operate out of a temporary location during demolition, cleanup and construction. ComEd has agreed to pay up to $33 million on the new library and up to $4 million on renovating the temporary location two blocks away.
In April, the Rockford Public Library Board and the Rockford City Council approved agreements with ComEd to move the project forward.
Prior to negotiations with ComEd, library officials wanted a partner to work on their behalf to help determine next steps to best serve the organization and community. The library board hired Fehr Graham, an environmental and engineering firm in Rockford, to consult and represent them throughout the project.
– Fehr Graham helped library staff and board members understand the environmental complexities with the property.
– Library officials relied on their consultant to review and explain environmental reports and process–oriented paperwork prepared by ComEd's consultant that reported findings to the library board.
– Library staff and board members became knowledgeable about the IEPA voluntary SRP, process and timeline.
– RPL had a sounding board and team of experts who reviewed and made recommendations to the environmental portions of the agreement with ComEd.
– The firm was present at the negotiations, leading up to the approved agreement in April.
The library is now renovating its temporary location. Once complete, it will move and remain in the location until the new library opens. The new, modern, state–of–the–art library is expected to open in four to five years.
– Provide periodic observation of all environmental work conducted by ComEd's consultant to ensure the environmental cleanup activities do not become an obstacle to the project timeline.
– Review all SRP reports to identify any potential setbacks and to ensure all work is progressing.
This project has many moving parts and includes many public and private partners. It was essential for the property owners to identify trusted partners who would work in their best interest to ensure the project has the best outcomes.


For scoring in this competition we accept only IGC files created directly from Condor software. Other methods, like upload FTR file to condor-club.eu and then back download IGC is not allowed! This generated IGC is invalid Condor IGC file and don't work for SCI scoring software.
1. What is a IGC file?
2. Is it importantly for me to upload a IGC file of my flight?
3. How can I create a IGC file in Condor?
After you have ended your flight, you see the following menue. Click on ANALYSE FLIGHT. Now click IGC EXPORT and save the IGC file by click on OK button. The name of the file is up to you (good idea is to store in format: Contest-YourCN-DayNumber). You can only save the IGC file in \Condor\FlightTracks\your.igc.
Navigate to the competition homepage and click on the login page link. On the left side navigate to menu item Send IGC, click on Search File button and search for your local IGC file - you find it usually in \Condor\FlightTracks\your.igc. Notice: some Windows Vista and Windows 7 users can find it in a "Virtual Store" directory for user - then local path is: \Users\Username\AppData\Local\VirtualStore\Program Files\Condor\FlightTracks. Then upload this IGC file by click on Upload IGC button.
5. I have forgotten to create a IGC file after the task, what can I do?
In the directory \Condor\FlightTracks\ is a file with the name LastTrack.ftr. You can load this file in the Condor under menu item FLIGHTANALYSIS and save a IGC file. But remember, you find only the last track, which means if you have flown a new task after the VirtualSoaring.eu task, you will only find the new one.


Preston is to get a £1.5m windfall to reinvigorate the Church of England in the city.
While the Catholic faith has been tightening its belt in recent years, the Anglican church has announced it is about to embark on an "exciting new era" locally.
And the plan will seek to encourage growth across Anglican traditions to meet the needs of a 'strong Anglo-Catholic' history in Preston.
Plans unveiled today show the cash will be pumped into improving the Minster and its partner church St George the Martyr off Lune Street.
The renaissance will also include reaching out to the city's student population, people under 25 and those without a church connection in a bid to help grow congregations.
And there is even a vision to create a new church to serve people from the new housing developments in the north of Preston, or on one of the city's social housing estates.
A new Vicar of Preston, to succeed Fr Timothy Lipscomb who retired in 2017, will be announced shortly.
The newcomer will be responsible for ensuring the plans become reality.
A new ministry team of between 10 and 15 individuals will be drafted in and will include clergy who will spend up to two years learning about "parish planting" - the setting up of new churches.
Significantly the team will also include a new full-time Anglo-Catholic priest to be based at St George's.
Building works at both churches are expected to be completed by late September when the diocese plans to formally launch the project.
Bishop Henderson said: "Thanks be to God for this next step in a very exciting adventure of faith.
The decision to award the funding to Preston was made last month - two years after the idea of a resourcing parish in the city was first proposed following a visit by the Bishop of Islington, who has a national remit for church planting.
Since then a team, led by the Bishop of Burnley, Rt Rev Philip North, developed the concept into a full-blown application for funding.
He said: "I'm really excited by the prospect of a resourcing parish in Preston, serving people from across church traditions, as well as people who have no connection to the church at all.
Bishop North was supported in the scheme by the Interim Vicar of Preston, the Venerable Michael Everitt, who is also Archdeacon of Lancaster.
St George the Martyr Church has long been described as Preston's "hidden gem".
Tucked away behind shops in Lune Street, the near 300-year-old building is the oldest church in Preston - and in recent years it has been showing its age.
It's future has been in doubt ever since Historic England included it on the "At Risk Register" of ancient buildings in urgent need of restoration.
Now the cash windfall from the Church of England will be used to address the structural faults which four years ago the former Vicar of Preston, Fr Timothy Lipscom, launched an appeal to resolve.
At the time Fr Timothy estimated it would take £750,000 to rectify problems with the walls and to restore its acclaimed organ.
The Diocese plans to bring in a full-time Anglo-Catholic priest to run the church, which was built in 1723.
The Blackburn Diocese says it wants to "foster unity among Christians of different denominations and traditions".
A statement issued today says that because the Parish of Preston has a "strong Anglo-Catholic tradition," one of the aims would be to recruit a team vicar "who will become a strong role model for Catholic evangelism".


text:
East Bay Mini Maker Faire
I've been going to the Maker Faire on and off over the years since it first started in 2006. The original one in San Mateo is spectacular, but it has gotten so big and crowded in the past few years that it's just not as enjoyable to me anymore as it was before it got super-crowded.
But the East Bay Mini Maker Faire, which just happened last weekend? Just the right size. Community-sized, and if you live in the area, there's a good chance you will run into more than one maker or attendee that you know.
At last weekend's event, I got to wear a "Maker" badge for the first time. I was helping the Alameda County Beekeepers Association, showing off a demonstration hive to visitors, answering questions, giving advice, and occasionally selling a jar of honey that came from my bees or from one of the other booth volunteer's beehives.
Is being a beekeeper really being a "maker" in the strictest sense of the word? Sometimes I would ask children at the booth just who were the makers at our booth, and they would invariably point to the bees. So, tongue in cheek, I covered up the "M" on my badge and hand-drew the letter "T" so it read TAKER.
Even if I'm merely taking care of the bees and collecting their excess honey from time to time, it's an activity that I enjoy becuase it's doing something in the real world, not the virtual world of websites and programming. It's a nice occasional break from my "day job" to check on the hives, collect honey, rescue a springtime swarm, and so forth.
Truly the best part of my experience at the beekeeper's booth this last weekend was talking to the kids who came up to see what was going on. They all had lots of questions, and many of them were starting from a good foundation of knowledge. (Are you having problems with hives dying out? Is the queen here in this hive? etc.)
Every kid — and just about every adult — who saw what I pointed out in the demonstration hive was excited and fascinated. The frames that could be seen thorugh the plexiglass were covered with brood (egg) cells, and throughout the day, it was pretty easy to notice a few "new bees" starting to hatch out of their cells. Maybe you could just barely see the antennae wingling out from a chewed-open hole in the cell, or maybe the bee had gotten its entire head out and was slowly emerging.
Photo CC
If you live near a Maker Faire — one of the main ones or a "mini" maker faire, I can't recommend strongly enough that you check one out. They are happening all over the world.
California's water waste is awful — but my idea to stop it may be counterproductive.
Last week I was down in Southern California, and I was astonished to see lush, green lawns all around me, at least in the town of Pasadena where I spent most of my time.
Considering that we are in the middle of a record-shattering drought in California, I couldn't believe my eyes.
So with a bit of image-searching in Flickr, my own iPhone pictures, and some inspired snark, I put together two hypothetical "public service announcements" that I wished would exist, to get people to realize how destructive and wasteful it is to be watering your lawns this year.
But a few days ago, I happened to read Think Like a Freak, the third in the Freakonomics book series by Levitt & Dubner. And I came upon a story that explained how public service messages just like this one, which draw attention to the behavior you want people to avoid, actually ends up increasing the bad behavior.
They discuss a study by Robert Cialdini where they found that the signs in Arizona's Petrified Forest National Park asking people not to steal pieces of petrified wood actually increased their theft.
Your heritage is being vandalized every day by theft losses of petrified wood of 14 tons a year, mostly a small piece at a time.
So I guess that means that pointing out to Californians how they are wasting water is just making it worse. So we need to come up with something that actually works.
But still, it's fun to dish out the snark, isn't it?
Srsly, we need to put a stop to Geneio/InstallerMac
As of last night, I can now say that over the last year, I have had to go to great lengths to extracate the horrible Geneio/InstallerMac malware off of every single Mac in my immediate & extended family (except, thankfully, my own.)
I guess for the basic Mac user, the alerts that InstallerMac puts up look innocuous and even helpful. Nobody remembers how it got installed. It might have been masquerading as an update to Adobe Flash in at least one instance.
Looking at the steps that are required to really remove everything that this malware leaves on your system, it's clear that this stuff is insidious.
Back in September of 2014, I submitted a bug report (18193924) to Apple begging them to do something about this. No response yet.
Doesn't it seem like Apple should take this kind of thing seriously? Isn't that what XProtect is supposed to help us avoid?
If you have a developer account and can get to bugreport.apple.com, why not submit your own bug report?
Since U Been Earworm
We've all been infected with earworms from time to time. Usually they go away, for me, after a couple of days.
Alas, Kelly Clarkson's 2004 breakout hit "Since U Been Gone" has been invading my consciousness for weeks, perhaps even months.
(No, I didn't listen to this video as I embedded it here!)
Why that song? I have absolutely no idea. It's not even listed on Billboard's list of the top forty earworm songs. (OK, no such thing, but really this chart ought to exist!)
To quote the Electric Light Orchestra song, I can't get it out of my head. Even the peaceful vistas of Yosemite National Park last week didn't cure it.
Apparently, scientists are saying that you can push an earworm out of your head by solving a mental puzzle like an anagram. That's all well and good, but I usually don't have a collection of anagrams with me to work on while I'm walking the dog or washing the dishes or driving/riding somewhere.
At least while I'm working, I can usually listen to my own choice of music to keep the earworm away. But heaven help me if I'm reading a book and it's quiet around me. Here comes Kelly, again.
One technique my brother suggested to me many years ago was to mentally sing to yourself the late-1980's TV show "It's Garry Shandling's Show."
Yeah, it works. But after 25 years, I'm getting a little bit tired of that song.
Anybody else have any suggested treatments for a case of earwormitis? Hopefully something milder than electro-shock therapy but even that's tempting if I could erase that song from my brain!
Grateful rants
At last week's Yosemite conference, Michael Lopp closed out the sessions with an inspiring talk about writing.
Thanks for unblocking the writer in me @rands - what a perfect way to end #cocoaconf at Yosemite! pic.twitter.com/sqR5JAbdVo
— Gautam Godse (@gautamgodse) April 23, 2015
One of his three suggestions for what to write about was to rant about something. (The other two, IIRC, were to clearly explain something you know and to express an opinion.)
Ranting is great. It's sure to get the creative juices flowing as your blood boils over thinking about the CIA hijacking Xcode or the state of the health care system in the US or the continued hazards in Fukushima or the wasteful water management practices of California agribusiness in the face of our crisis-level drought. And if you can write about these things, and spread understanding of knowledge that might improve the situation, that's great. If we didn't have people writing, blogging, tweeting, talking about these issues, they'd just be swept under the rug. (In fact, many important issues still are largely ignored by the public.)
But often ranting (usually on social media, not so much in long-form writing) ends up just complaining and spreading negativity. Like that crying baby in the airplane a few seats back, or having to wait for the dishwasher repair dude too long, or the bad service you got at the restaurant.
To me, all that seems to do is to amplify the negativity for yourself, and spread negativity to others.
To me it seems like the people who complain a lot are the ones who seem to always have these things happen to them. They guy who rants about babies crying in the movie theatre? It seems to happen to him a lot. It's like the complaining attracts more negativity.
At Yosemite, one of the presentations — I think it was the one by Jamiee Newberry, who talked about her "31 days 31 people" project of expressing gratitude — reminded us to focus on what's good, and be grateful as a way to be happier.
So I'm personally going to modify Lopp's advice to rant, and come up with a type of rant that's not negative! How about ranting with gratitude?
I'm considering some grateful rants to post in the days or weeks ahead. Stay tuned.
Yosemite: A State of Mind
Mac developers and Mac enthusiasts probably equate "Yosemite" with the 10.10 version of the operating system; most others in the world equate the word with California's gorgeous, dramatic park.
This last week, I was privileged to firmly place myself in both camps, by attending the conference Yosemite, by CocoaConf. Their tagline of "The Apple Conference with a View" sure wasn't kidding.
The conference wasn't a technical conference at all. And yet I think I learned exactly what I needed to learn, both from the presentations and in between them. (And I'm not just talking about 10-minute bathroom breaks. There was a break between the morning sessions and the evening sessions where groups of us might go for an easygoing interpretive or photographic walk about the valley floor, or a vigorous climb up the Mist Trail to Vernal Falls.)
The talks at the conference were entertaining and profound. And while the presentations were conceived and delivered independently, the theme connections between talks were so strong that it felt like they were part of a planned network.
The presentation by Christa Mrgan blew me away because it had elements of Yosemite, iOS design, and personal perspective all rolled into one. She walked us through the design of a hypothetical iPhone app about the gorgeous High Sierra Camps, where she used to work for several summers. (I think that by the end of the talk, we all wanted that app to exist, and we all wanted to be at the hike-in accomodations that she described. Maybe the next CocoaConf Yosemite could be somewhere accessible only by hiking in, with equipment packed in via mule?)
Andy Ihnatko (I'm imagining that the "H" in his last name might indicate aspiration — a puff of air, when pronounced, extrapolating from what we learned from Laura Savino) told us what he really thinks about the ten-thousand-dollar Apple Watch; his perspective on the importance of not being constantly bombarded by information and distraction was echoed in many other talks as well.
James Dempsey (Billboard-charting artist), surrounded by several breakpoints and conditional breakpoints (who played guitar and sang excellently), rocked the house with his über-geeky songs. I wish I had brought my guitar so I could jam along (though I could never hold a candle to the guitar skillz of Jim, Brent, and Dave.)
That's just a small sampling of the wonderful presentations. Oh, and Michael Lopp inspired us all to start — or restart — writing. The result is manifested here; let's see if I can keep it up. Oh, thanks for the awesome pen.
All in all, the Yosemite conference was inspiring and amazing, both inside the building and outside of it. My thanks to the Klein family for organizing the event, the many speakers who were either old friends or, hopefully, will become new friends, and the many attendees I got to know (especially by following the C4 habit of sitting at a table with people you don't yet know). I raise my glass in a toast!
© Fernando Morgan, used by permission.
Yosemite's "Mail Drop," with plain text emails, considered harmful.
Yosemite has a cool new feature "Mail Drop" which is really handy for sending large files without having to resort to file-sending websites or DropBox (or its non-Condoleezza-Rice competitors).
If Apple Mail detects a giant attachment, it will offer to send it via Mail Drop, which means that the file is uploaded separately to a temporary iCloud URL. It will stick around for 30 days.
The problem is that if you use this technique, it's possible that any actual textual message might not be seen by the receiver of the email message.
If you send your email message as plain text — you might not even realize that you are sending a plain text message or a rich text message —or if the receiver's email client shows them plain text instead of rich text — then ONLY the Mail Drop URL will be seen by the receiver. Not your important message.
Here's an example message I might compose. (I use a monospaced font to display plain-text messages, but if you use a proportional font, it might be that obvious.)
The message transmitted doesn't even contain the text; it only contains the Mail Drop URL:
Even if you commit to never sending a plain-text message with Mail Drop attachments, and you deselect Mail's preference "Use the same mesage format at the original message", you are not out of the woods yet. If the receiver is using a mail client that prefers the plain-text portion of rich-text messages, then the problem happens there too. That's because the plain-text portion of the rich-text message lacks any text besides the Mail Drop link. Here's an excerpt of a rich text message's raw source — note the text/plain segment containing only the URL.
This is a real concern! For instance, we use FogBugz for tracking support cases, and while I want to encourage people to use Mail Drop for sending us large files when needed, we need to go through a lot of hoops just to determine if their message had any useful textual content in it. Because all we see in a message that included a Mail Drop attachment is a big honking URL.
This isn't just a rant; I've reported this to Apple (radar 18756471). Hopefully they take it seriously! If you, dear reader, know about Apple radars, feel free to file a duplicate if you think it's sufficiently annoying.
TeamViewer: Handy for helping with Mom's Mac
If you have a family member or friend for whom you end up taking care of their Macs, you may want to share their screen and take over their computer so you don't have to spend hours giving them instructions on what to do and asking them to read what it says.
I tried using screen sharing with my mom, but her router wasn't going to let that work. Messages.app didn't let her share her screen for some reason. But then she came across TeamViewer. And it works really nicely.
They way it works is that you both launch the app, and Mom tells you her ID and password; you enter her ID (and then her password) and you are on your way!
Ken Wood, 1932 - …2014
My father passed away yesterday after a long, losing battle with Parkinson's disease.
And yet, I already was saying goodbye to him in some ways for over a year. That's why his ending date really wasn't 2014. Because his Parkinson's took a bit of him away at a time, to where there wasn't much left when his body finally finished its journey.
And though many reading this memorial never knew him — or don't know me, for that matter — this is my memorial to Kenneth Herbert Wood.
These years have taken an especially hard toll on my mother, who could no longer care for him at home. But even with my father at a care facility, she still had many duties to perform, while spending an unbelievable amount of money. When Dilbert's Scott Adams published his essay "I Hope My Father Dies Soon," it certainly struck a nerve.
When I would visit him, at first he was mostly "there," mentally. He even achieved some fame within the facility and made the local TV news with a feature on him, due to his talent at drawing amazing portraits of his fellow residents. (Somehow his shaking hands would calm down when he was drawing.) But then he deteriorated more, mentally and physically. When I would see him, there would be some of the man I remember, but not much. And less each time. So over those months, I found myself saying goodbye to him, at least in my own heart. He was shrinking, reverting, losing memories and physical abilities.
Then, late last week, he took a major turn for the worse, and never woke up. And I'm very sad that he's gone, but it's also a blessed relief that it is over.
I try not to think of the recent months where his body, even his face barely resembled its former self. Instead I try to think of the hero that my father was, and replenish my mind with memories of before the Parkinson's.
My dad was artistically creative his entire life. As long as I can remember he had been drawing, mostly cartoon-style. He would apply that talent to drawings he'd give as gifts to the kids, or make into personal greeting cards for friends, or wherever something graphical was needed, or in support of his work. He'd create advertisements for the local country newspaper and community events.
When I was about 10, he started creating some children's books. "The Pickle Machine", "Exactly Like Me", and "Jeremy Dingle" never were published — he tried but didn't get any bites from publishers — but they delighted us and have delighted my kids as well.
Another example of how the Parkinson's took hold was related to one of his children's books. I had made a color copy of "The Pickle Machine" for my nephew so that he could enjoy it too. But for reasons unknown, my dad decided to rework the story, and had grand plans for changing the story. Though he wasn't able to draw much, he would obsessively redo parts of the story, having whoever was near him help him cut drawings out, re-write the text, and rearrange sections. And yet nothing of what he was doing made any sense. It got to a point of mania. Finally, in a moment of clarity, he consented to putting the entire project away on a high closet shelf.
Fortunately, the original, unaltered version still rests in my house. I have no desire to keep, or even see again, the Parkinson's remix.
When I was born, my parents owned a stereo shop back in the sixties, Woodland Stereo Center in Woodland Hills, California. (Yes, one of the brands sold there was Kenwood!) The picture below was taken shortly after I was born, if you notice the addendum to the main sign!
But when I was about seven, my parents – from the generation too old to be considered hippies — got bit by the "back to the land" movement in the early seventies and decided to move from the suburbs of Los Angeles to the country in Northern California. I remember being driven around in our family's blue VW van while my parents looked for a place to live and start a new life. Finally we found an 18-acre property in the Sierra Nevada foothills, completely undeveloped, and decided to stay.
And on that property, with the help of my mom and some neighbors — and as much as we could, the kids — he built a house. From scratch. And while it was never quite finished – we moved in way before there where amenities such as wallboard or plumbing or electrical outlets — I lived in the house my dad built until I moved away for college.
Though my dad was weakened terribly in his last years — it seemed like the Parkinson's aged him by more than a decade within the span of a year or two — most of my memories of him were being incredibly strong. He had to be, as a forty-something-year-old homesteader. Carrying two five-gallon buckets of water uphill from a nearby stream, building barns and temporary quarters and then our house, hauling 10-gallon milk cans, my mother proudly called him the "homestead gorilla."
Ken never had a single career track — the farming never really made a decent living for us — but overall I'd say that his biggest strength was sales. Selling hi-fi's and stereos, then after moving on from the farming, he'd done well with selling advertising, solar water heaters, encyclopedias (along with my mom in that venture), and so on. A skill that I never could quite grasp, yet he excelled at it and thrived at it.
His biggest love — besides his family — was music, though. His classical record collection — on LP and reel-to-reel tape; later on CD — was enormous. He enjoyed very little in the popular music genre, though he did have a weak spot for the lead singer of the Stone Ponies, Linda Ronstadt (who, as it turns out, is now afflicted with Parkinson's). While he tolerated the music that his kids listened to growing up, it was Beethoven and Mozart and Schubert and Chopin on the stereo in my house growing up. And opera, which I never really could appreciate the way I eventually started appreciating orchestral music.
In his last year or so, he had a small stereo and a modest collection of his favorite music with him at the "old folks' home." I'm glad he had his music to keep him company, though I don't think he was really able to make use of the equipment for the last few months.
Ken didn't just listen to music during his lifetime. He was a singer — a tenor — who sang every chance he got. Growing up, I remember going to see him solo in Handel's Messiah every year. While I never picked up a love for opera, I relish my memory of seeing him perform in Sacramento in the chorus there shortly before his diagnosis. I have a cassette tape — I ought to digitize it — of some of his favorite classical songs that he'd sing. (Schubert's "Was ist Sylvia" for example, or his parody of "Granada" called "Granola", a tribute to the crunchy cereal.)
Parkinson's took away his singing and speaking voice, gradually, though sometimes there were little reprieves. I wasn't there, but a couple of years ago, there was a memorial service for a friend, at a time when the disease had taken away most of his voice, where he found himself singing, full-strength, a song in tribute at the memorial. For those who knew him there, it seemed like a small miracle. I wish I had been there for that.
I also remember him acting — a talent that completely skipped my generation. But he loved performing in community theatre, and also created a one-man show that he would perform week after week at a local campground resort, where he would play the famed stagecoach robber Black Bart.
Last year, my mom found an old reel-to-reel tape that was labeled somewhat cryptically along the lines of "Baby Announcement." Intrigued, but with no machine to play it on, I took it home. Some research found a service that would convert a reel-to-reel tape into MP3 audio. Taking a gamble, I ordered a digitized recording. What came back (over a file download) was a treasure. When I was born — I'm the oldest — my dad had come home from the hospital, fired up his tape recorder, and called the relatives to announce my arrival. Hearing his speaking voice at its full strength — he was younger than I am now, actually — was amazing. I could also make out the voices of my grandmothers through the phone. Later in the tape, interspersed with odd recordings of music and television, so I'm glad I kept at it — I found other recordings from my own early childhood that he made while he was watching me. Amazing. What a great vault of memories from my life, from a time when I was too young to remember myself.
My dad was an amazing man and a loving father. And I know we had a good relationship throughout the entire intersection of our lifetimes. And I will miss him terribly.
And after all that Parkinson's disease took from him, I'm glad that his journey is finally over.

redpajama_set_name: RedPajamaCommonCrawl


The Commissioner of Police has tasked Kukum Traffic to look out for unauthorised and after hours use of government vehicles.
In a press conference last week, Commissioner of Police, Mohammed Jahir Khan, expressed concern over the increase of reports of G-plated vehicles being used for private purposes after official hours.
Mr. Khan said government vehicles are state assets and using them inappropriately for one's personal benefit is misusing government property.
On three G-plated vehicles reportedly involved in motor vehicle accidents last weekend, Mr. Khan said this is not only a traffic matter but a national concern as government property and assets are not being cared for.
He said it is more concerning to see government vehicles parked at night club areas around Honiara.
Mr Khan warned that those found misusing or illegally keeping a government vehicle will be dealt with accordingly.


Check out my lonely H&R Block App on the home page of my iPad. Yes, that is a cool picture I took from a past trip to Las Vegas that I use as my wallpaper. For the first time ever, I used an iPad App to file my taxes. As you can tell, I like to procrastinate until the last possible day. In the US, today is the filing deadline for Federal Taxes. I liked the App so much that I gave it 9 out of 10 stars. It was free, my filing process was simple and free, and my rather small tax refund should arrive electronically in my bank. Isn't technology wonderful?
This entry was posted in Stuff and tagged App, Apple, Application, Federal Income Tax, H&R Block, iPad, Las Vegas, Screenshots, Stuff, Taxes, Wallpaper.


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We're open Tuesday – Thursday during term time and offer a two or three course lunchtime menu plus a daily special dish. We also host regular theme evenings where you can try a whole host of cuisines.
Every time you dine at Hart Kitchens, you're contributing towards the future of our catering and hospitality students who gain valuable work experience by working in the restaurant as trainee chefs and waiting staff.
Hart Kitchens gives our students the opportunity to practice their skills by laying out tables, hosting, preparing food, cooking, serving, stock management, event planning and customer service.
Our students at various course levels work in different roles within the restaurant, with higher level students planning and delivering menus for the theme evenings that we run throughout the year.
When you dine with us, don't forget to get your Hart Kitchens loyalty card stamped! When you collect eight stamps, you'll receive a complimentary three course lunchtime meal.
We are open every Tuesday, Wednesday and Thursday.
Lunchtime hours are 12pm - 2.30pm, with last orders at 1.30pm. Lunchtime prices are £6.95 for two courses or £7.95 for three courses.
Our calendar of theme evenings is available to see, with menus.
Our next themed evening is a Best of British - St. George's Day Special on Thursday 26th April, a celebration of traditional British dishes.
Don't forget to leave us a review on TripAdvisor.
Sign up to our monthly newsletter to keep up-to-date with all the latest news and events from Hart Kitchens. To sign up, fill in the contact form below.


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The recently appointed Minister of Trade and Investment, Dr. Olusegun Aganga on Saturday, 13th August, 2011 embarked on a visit to the Tinapa Free Zone and Resort in commencement of his nationwide tour of Free Zones in the country.
He was received upon arrival by members of the Tinapa Management led by the Managing Director, Arch. Bassey Ndem who thereafter conducted the Minister and his entourage on an extensive tour of Tinapa facilities.
At a Media parley after the tour, the Minister explained that his visit to the Resort was part of his official tour of all Free Trade Zones in the country with a view to assessing the progress so far made in the implementation of the Federal Government's Free Zone policies. He reiterated his Ministry's intention to follow up with measures that would enhance the performance and productivity of Free Zones as well as ensure their contribution to national development.
The newly posted Customs Area Comptroller (CAC) of the Nigeria Customs Service in charge of the Cross River, Akwa Ibom and Free Zones command, Mr Ibrahim Abdulateef has on Tuesday 20th June 2011, paid a courtesy call on the Managing Director and CEO of Tinapa, Arch. Bassey Ndem.


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GLOBAL ENERGY TRANSFORMATION
Full Title: GLOBAL ENERGY TRANSFORMATION
Author(s): IRENA
Publisher(s): International Renewable Energy Agency (IRENA)
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Increased use of renewable energy, combined with intensified electrification, could prove decisive for the world to meet key climate goals by 2050. This study from the International Renewable Energy Agency (IRENA) highlights immediately deployable, cost-effective options for countries to fulfil climate commitments and limit the rise of global temperatures. The envisaged energy transformation would also reduce net costs and bring significant socio-economic benefits, such as increased economic growth, job creation and overall welfare gains.
The report – the second under the Global Energy Transformation banner – expands IRENA's comprehensive roadmap, which examines technology pathways and policy implications to ensure a sustainable energy future. Ramping up electricity to over half of the global energy mix (up from one-fifth currently) in combination with renewables would reduce the use of fossil fuels, responsible for most greenhouse-gas emissions.
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1) How can I restrict what the punchout user sees?
Filtering catalog items are done within the Views session. If you have 100,000 items but only 3,000 are categorized as office supplies that only certain users have access to, then a view based on office supplies would be required.
a) In Views, click Add view.
c) For the new view, click Attributes.
d) Click Edit for the attribute that that needs to be filtered. For this example select the attribute Category.
e) Enter in the Included text box the name of the category. If there is more than one category then separate the categories by a comma and a space.
f) Click Update Attribute, and the Included column will now contain a check mark for Category attribute.
g) Now when the user first enters the punchout or clicks All categories, only "Cleaning Equipment and Supplies, Paper Materials and Products" will be displayed for that view.
If the requirement is to have multiple views for the catalog, then for each specific view to be enabled in the punchout, a distinct user needs to be created and assigned to that view.
For example, if we need a view for "Mexico - Chemicals", we would create another user called mx_chemicals and assign the view "Mexico - Chemicals" to the user mx_chemicals.


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2020| January-June | Volume 34 | Issue 1
Online since July 6, 2020
Nebulization in the pandemic of coronavirus disease 2019
Subodh K Katiyar, Sandeep Katiyar
January-June 2020, 34(1):8-14
DOI:10.4103/ijaai.ijaai_29_20
Inhaled therapy is the cornerstone in the management of obstructive airway diseases (OADs). Nebulization is often used for the delivery of bronchodilators and corticosteroids among the elderly and children. The present pandemic of coronavirus disease 2019 (COVID-19), caused by a newly identified, highly contagious, novel coronavirus, called severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), is responsible for great morbidity and mortality globally. There is a great concern regarding person-to-person transmissibility of this virus. There is also a great concern of viral transmission of this virus to the health-care personnel and the bystanders through aerosol-generating procedures including frequently used nebulization therapy. Most of the patients with OAD, during the current pandemic, who were undergoing nebulization therapy, on getting infected with SARS-CoV-2 or on its suspicion, have been shifted to other handheld devices out of fear of transmission of infection. Presently, there exist not enough evidences either on the safety or on the risk of transmissibility of SARS-CoV-2 during nebulization in COVID-19 patients. In addition, there are concerns about nebulization in OAD cases even in the absence of COVID-19 and about the use of inhaled or systemic corticosteroids in these cases. We have made some observations based on all the current information available related to these issues, which may help provide some guidance in the use of nebulizer therapy and also discussed the measures to be taken to minimize the risk of infection, if any, during the procedure.
[ABSTRACT] [FULL TEXT] [PDF] [Mobile Full text] [EPub] [CITATIONS]
Covid-19 immune mechanisms: A systematic review
Shalini Gandhi, Sandeep Kumar Sharma, Purva Shoor, Jitender Sorout, Abhay Raina, Rohit Raina, Urvashi Miglani, Uma Kant Chaudhari, Shivi Srivastava
January-June 2020, 34(1):23-27
There is a new public health crises threatening globally with the emergence and spread of 2019 novel coronavirus or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is the seventh member of the coronavirus (CoV) family, which infects humans and to which the Middle East Respiratory Syndrome CoV (MERS)-and SARS-CoV also belong. SARS-CoV-2 is a newly emerging human infectious CoV that causes COVID-19, which has been recognized as a pandemic by the World Health Organization on March 11. The most recent outbreak initially presented as pneumonia of unknown etiology as COVID-19 is a pneumonia-like disease with a group of symptoms including fever, dry cough and shortness of breath in a cluster of patients in December 2019 Wuhan, China. The body's immune system tries to protect the body from this pathogen. And as due to its surge in the body, various respiratory and other system-related complications increased. Therefore, in this article, COVID-19 immunopathogenesis is briefly reviewed. Through this review, we try to explain the molecular immune pathogenesis and diagnosis of COVID-19 (SARS-CoV-2) infection, based on the recent research progress of SARS-CoV-2 and the knowledge from researches on SARS-CoV and MERS-CoV.
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Management of asthma and allergic diseases during the coronavirus disease 2019 pandemic in India
Nagaraju Kuravi, Karthik Nagaraju, Venkata Kasyapi Voorakaranam
Coronavirus disease 2019 (COVID 19) is caused by the novel coronavirus, which has affected 184 countries and the WHO has declared it a pandemic on March 2020. Allergic diseases such as allergic rhinitis and asthma are exaggerated by viral infections. Symptoms of allergic diseases overlap with COVID 19. Current recommendations include following social distancing and frequent hand washing. Confusion exists regarding the use of corticosteroids, biologicals, and immunotherapy for the treatment of allergic diseases during COVID 19 season. Due to the use of Personal Protective Equipments, reports of contact dermatitis are emerging among health-care workers. Remote consultation, like telemedicine, is a valuable tool in this pandemic. This article aims to provide guidance on the management of allergic diseases taking into consideration existing evidence and guidelines from international organizations and the feasibility of implementation in India.
COVID-19: A global crisis
Nikhil Sarangdhar, SN Gaur
January-June 2020, 34(1):1-4
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Recommendations for allergy practice during COVID-19 pandemic in India
Mahendra K Agarwal, Anand B Singh, Shailendra N Gaur, PC Kathuria, VK Jain, Mahesh Goyal, KV Nagendra Prasad
We are living in an unprecedented difficult time due to the infectious COVID-19 pandemic, a global emergency. During the on-going pandemic, most allergy/immunology care could be postponed/delayed or handled through virtual care. Seven experts from different parts of India deliberated on this subject in 3 weekly webinars (May 10, 17, and 24, 2020) charted out consensus-based approach for diagnosis and management of patients suffering with allergic respiratory diseases in India during this COVID-19 pandemic. This publication includes these recommendations.
The epidemiological and trending pattern of nCOVID-19 in the state of Rajasthan, India
Sudhir Bhandari, Ajeet Singh, Subrata Banerjee, Raman Sharma, Govind Rankawat, Vishal Gupta, Prakash Keswani, Ashwin Mathur, Abhishek Agarwal, Shrikant Sharma, PD Meena
PURPOSE: The present study was undertaken to investigate the behavioral distribution pattern and progression of coronavirus disease 2019 (COVID-19) across age and gender in the state of Rajasthan, India, inherently distinctive and native to localized part of the globe giving requisite information and paraphernalia to designate advisory board of the state to design and frame customized policy for demands of the state as per the trending pattern relative to age and sex distribution, profile of new infected cases, recovery rate, and case fatality rate. METHODS: The present ongoing study assessed patients admitted till April 22, 2020, across the state of Rajasthan, India, with reverse transcriptase-polymerase chain reaction (RT-PCR)-confirmed COVID-19 test. Analyses of the patients included characteristic age and gender distribution through the geographic identities of state along with the time trending pattern of newly infected patients, recovered patients, and case fatality rate. RESULTS: A total of 1888 sample patient population of RT-PCR-confirmed COVID-19 was evaluated, with the majority of sample patient population being in young adult age group with a mean age of 34.42 years. Nearly 11.65% of the patients were below 15 years of age, 34.79% were in the age range of 16–30 years, 25.90% were in the age group of 31–45 years, and 17.69% were in the age group of 46–60 years, with only 9.95% of the patient population being in the age group of above 60 years. Interestingly, 11.65% of patients with COVID-19 were in the pediatric age group. The percent of affected females (37.35%) was much less than that compared to males (62.65%), with an average sex ratio of 0.59. Across the sample patient population of 1888, 543 patients recovered fully, 25 patients died, and 1320 cases were active in the said time frame, with an average recovery rate of 28.76% and a case fatality rate of 1.32%, and the remaining 69.91% of the patient population made up the active case group. The timeline and the trending pattern of COVID-19 in the state of Rajasthan was suggestive of an increasing rise of number of new cases with antecedent mortality, though a reassuring concomitant rise in the recovery rate of patients could also be appreciated. The infective COVID-19 dictum of spread through contact could very well be appreciated in select geographic hotspots and/or zones, and 108 sample patient population was from out of Rajasthan. CONCLUSION: It was interesting to observe that majority of the resident population of the state of Rajasthan that was COVID-19 positive was in the young adult age group of 30–50 years inclusive of pediatric patients, an observation that is different from reports as documented from across the world. Male population seemed to be more prone to infection. The time frame in which the evaluation was done is suggestive of an increasing trend in the number of new cases with antecedent case fatality, though recovery was also on the rise indicative of a potential decreasing load. The geographic mapping of COVID-19 patients could be established through contact tracing.
Spectrum of diagnosis of hereditary angioedema: Seven case reports
PC Kathuria, Manisha Rai, Neelam Kathuria
Hereditary angioedema (HAE) is a potentially life-threatening disorder, due to a mutation in complement one-inhibitor (C1-INH) gene, which blocks the activity of various components of complement – fibrinolytic and bradykinin control system. Our seven cases of HAE give different clinical presentations of TYPE I/II/III HAE as facial, abdominal, laryngeal, and genital involvement along with comorbidities (5 cases) such as hypothyroidism, rhinosinusitis, and hypothalamic–pituitary–adrenal suppression, and four cases have had history of recurrent abdominal attacks. Treatment with Pdc-INH concentrate and self-administrated Icatibant provides consistent and reliable efficacy in those who have had multiple successive HAE attacks, with the involvement of all body parts. However, if pdc-INH concentrate is not available, then fresh frozen plasma and androgens (Danazol) can be used in emergency. Our cases demonstrate the importance of diligent clinical and family history with special tests: C4, C1-INH quantitative, and C1-INH functional.
Clinical, radiological, and immunological assessment of allergic bronchopulmonary aspergillosis
Anshika Jindal, Yogendra Singh Rathore, Shubhra Jain, VK Jain, Vinod Joshi
INTRODUCTION: Allergic bronchopulmonary aspergillosis (ABPA) is an immunologically mediated lung disease, predominantly in patients with asthma and is caused by hypersensitivity to colonized dimorphic fungus Aspergillus, commonly Aspergillus fumigatus. Early diagnosis with recognition and treatment of chest radiographic infiltrates appears to prevent progression to end stage fibrosis. Many cases are mistreated as pulmonary tuberculosis or recurrent pneumonia and are deferred for specific treatment of ABPA. AIM AND OBJECTIVES: This study aims to know the clinical, radiological, and immunological profile of patients diagnosed with ABPA reporting to the Institute of Respiratory Disease, SMS College, Jaipur and Mahatma Gandhi Medical College, Jaipur. MATERIALS AND METHODS: Hospital-based prospective, observational, cross-sectional study was conducted in 48 Patients having history of bronchial asthma, pulmonary infiltrate/shadows on chest X-ray were subjected to routine investigations, immunological tests including modified skin prick test with specific IgE against A. fumigatus and specific precipitins against A. fumigatus. RESULT: In this study, maximum predominance with age group of 21–40 years irrespective of sexpattern. Maximum patients were having bronchial asthma of 2–10 years duration. Cough, breathlessness, and wheezing were main clinical features. In 80% cases, total eosinophilic counts were more than 1000.58.4% sputum were fungal culture positive, maximum for A. fumigatus. All cases showed modified kinprick test positivity against A. fumigatus. Maximum patients high-resolution computed tomography chest had central bronchiectasis. 37% cases had raised total serum IgE (range 1000–5000). Specific IgE against A. fumigatus were positive in 24 patients. 87.5% patients were positive for specific precipitins. CONCLUSION: In this study, ABPA was found more commonly in people with chronic asthma of productive age group, i.e., 20–40 years and farmers by occupation. Most of the people were diagnosed as having pulmonary tuberculosis and deferred specific treatment for a long time. More knowledge about ABPA to physicians could possibly cut short the time between suffering, diagnosis, and proper treatment of these patients.
Sensitization to indoor allergens in children with bronchial asthma
Komal Chauhan, Shetanshu Srivastava, Rajendra Prasad
BACKGROUND: Children with asthma have a high prevalence of environmental allergies. Sensitization to various allergens, especially to indoor allergens is crucial for effective measures for asthma management. Indian data on allergic sensitization in children is scarce, necessitating the need of the study. METHODS: A Cross-sectional study was conducted to determine the indoor allergen sensitization in 100 asthmatic children aged 5 to 15 yrs. They underwent skin prick test for indoor allergen house dust mite cockroach, cat, dog dander, house fly, candida, aspergillus, and mosquito. RESULTS: In the study sensitization to house dust mite was 93%. 39% were sensitized to Candida 36% to cockroach,23% housefly and 22%to dog dander and Aspergillus and 13% to mosquito and cat dander. Allergen sensitivity rate for atleast one allergen was 94% which was significant. Mean No. of allergens for which sensitization was seen is 2.57±1.77. Comorbidities were present in 35% of cases.7% had urticarial and allergic conjunctivitis each. CONCLUSION: Asthmatic children showed high sensitization to indoor allergen and the most common allergen found was house dust mite
Selective immunoglobulin M deficiency: An underestimated immunodeficiency disorder – not so rare
Arun Agarwal
Immunoglobulin M (IgM) is the first antibody to be produced during an immune response, and most of the primary humoral immune response is mediated by IgM. Selective IgM deficiency (sIgMD) is a rare immune disorder that has been reported in the association with serious infections. Patients with sIgMD may be asymptomatic; however, approximately 80% of patients present with infections with bacteria, viruses, or protozoa or with an associated allergic, malignant, or autoimmune condition. sIgMD is usually identified when evaluating a patient for recurrent or serious infections. Attempts should be made to document the infection, as well as the responsible organism, whenever possible. It is a diagnosis of exclusion, and formal diagnostic criteria have not been established. We report three adult cases that were diagnosed to have sIgMD during the evaluation for serious polymicrobial infections with bacteria, fungi, mycobacterium, and viruses. One of them was diagnosed to have associated lymphocytic leukemia. All were successfully managed with intravenous Immunoglobulin (Ig), antibiotics, antiviral, supportive treatment, and discharged. We conclude that patients presenting with polymicrobial infections with encapsulated bacteria, fungi, mycobacterium, and viruses should be evaluated for specific antibody deficiency responses, and they appear to improve clinically on Ig therapy. It appears that the disorder is underdiagnosed.
© Indian Journal of Allergy, Asthma and Immunology | Published by Wolters Kluwer - Medknow
Online since 10 October, 2012