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Q: Как задать интервал между возможностью применения события? Как задать интервал между возможностью применения события?
Например чтобы после нажатия на div следующее нажатие можно было повторить только через 3 секунды
https://jsfiddle.net/nnj4m728/1/

$('div').click(function(){
 alert(665);
});
div {
 height: 200px;
 background: #000;
}

A: Можно установить булевый флаг, отображающий возможность клика. После этого биндим на клик запрет повторного клика, а через задержку setTimeout() возращаем эту возможность:

$('div').each(function() {
  var clickable = true; // флаг
  $(this).on('click', function() {
    if (clickable) { // если кликабельно
      clickable = false; // запрещаем клик
      alert('665'); // ваш код для выполнения по клику
      setTimeout(function() { // запускаем таймаут
        clickable = true; // возвращаем кликабельность
      }, 3000); // задержка в миллисекундах
    }
  });
});
div {
  height: 200px;
  background: #000;
}

Вариант #2: определять кликабельность наличием/отсутствием класс. Реализация практическая такая же, как и с флагом:

$('div').on('click', function() {
  var div = $(this);
  if (!div.hasClass('disabled')) { // если не заблокировано
    div.addClass('disabled'); // запрещаем клик
    alert('665'); // ваш код для выполнения по клику
    setTimeout(function() { // запускаем таймаут
      div.removeClass('disabled'); // возвращаем кликабельность
    }, 3000); // задержка в миллисекундах
  }
});
div {
  height: 200px;
  background: #000;
}

Вариант #3: блокировать клик через CSS, используя свойство pointer-events:none:

$('div').on('click', function() {
  var div = $(this);
  div.addClass('disabled'); // запрещаем клик
  alert('665'); // ваш код для выполнения по клику
  setTimeout(function() { // запускаем таймаут
    div.removeClass('disabled'); // возвращаем кликабельность
  }, 3000); // задержка в миллисекундах
});
div {
  height: 200px;
  background: #000;
}

div.disabled {
  pointer-events: none;
}


When Benefit Cosmetics put out their runaway favorite Benetint, the average makeup consumer went nuts. "Now I can have gorgeous red lips just like the girls on Friends," we all said. And then we tried it—gorgeous red, yes, but sometimes very hard to work with, given the liquid tint's habit of drying too fast for proper blending. But Benefit listened and responded, and now they have me firmly back in their product pocket. Their Benetint Lip Balm is a dream—soft, emollient, vitamin-drenched rosy tint for my lips, which are now juicy and kissable 24/7! And I can't wait to try their Pocket Pal, a mini original Benetint on one end (with handy sponge applicator for ease) and sheer, shiny gloss on the other.


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Eye For Film >> Features >> Working girls
Henrika Kull on sex work, feminism and Bliss
by Paul Risker
German director Henrika Kull takes audiences inside a working Berlin brothel, in her sophomore feature Bliss. The drama centres on the romantic relationship that forms between Sascha (Katharina Behrens) and new girl Maria (Adam Hoya), but their insecurities and struggles to open up threatens their hopes of finding something more emotionally permanent.
In conversation with Eye For Film, Kull discussed taking her audience into unfamiliar spaces, challenging preconceptions and changing perception.
Paul Risker: Filmmakers are often asked what they want the audience to take away from a film. Speaking with directors, I get the sense they're often not trying to tell the audience anything, but instead give them an experience. Is this how you approach filmmaking?
Henrika Kull: Yes, and the places I go in my research, for example with my first film Jibril, was to prison, but also the Arab community of Berlin, and here it was an actual brothel. I was fascinated and fell in love with all the people in this place, and the wrong expectations. I love my job when I get to experience these kinds of places, and this is something I want to share with the audience. I want to show them these places in a new way, as I experienced them, as authentic as possible, but still with fictional characters, by bringing them into environments they wouldn't usually see. Also, by finding the beauty in the places that aren't supposed to be beautiful.
PR: The spaces here are perceived as dirty, taboo and degrading. I don't believe it's a fair judgement of either these women in the brothel or the recriminations directed towards the pornography industry. We habitually push people to the fringes and condemn them without trying to understand the person or the work. Your film shows them to be regular people earning a living, and there's an interesting conversation about the low pay of shop work. These women echo a disillusionment that's a common reality, showing that they're not that different, instead it's an issue with how how they're viewed.
HK: It's crazy that they're suffering mostly from the stigma of society, not from their job, and they're forced to live this double life and not be honest. Still, I'd never say I love the fact that sex work exists, or that I love the patriarchal system in which sex work can exist, because it's still something that generally women do for men, not the other way around. In patriarchal thinking and in capitalism, it works like this and I don't like it.
I wanted to portray the strength of these women and how they're more empowered than the women outside. They're aware of the structures and the system, and they somehow see it in an ironic way. It doesn't necessarily have to be feminist or intellectual, but being inside of those structures every day allows you to understand the irony of the structures of power, money and sex. I wanted to say that this is a normal job and if a woman decides she wants to do it rather than work in a shop, then she can, but I don't want to say I appreciate the existence of sex work.
PR: Your approach is to not excuse nor condemn, and instead of choosing a side, you show for better or worse, this space is a common reality.
HK: … It felt to me that the women inside the brothels were the ones that have the power to set the boundaries. It's a service, or a deal, and outside of that it's harder to set the boundaries because they're not clear, and there's a lot of toxic masculinity and misogyny, even if men, or society say that we're very pro-female and feminist – it's still not true.
There's an interesting flip when you go to a brothel because something changes, and that's what was so fascinating. I went to many brothels and spent a lot of time in them over the years. I always felt a little matriarchal because they're laughing about men and how they function, and it somehow deconstructs them. … It's why I always went back. I loved these special women who when we were shooting, would be sitting around and making fun of their jobs, their clients and the whole capitalist and patriarchal system.
PR: Are you optimistic about the progress we're making towards gender and racial equality?
HK: I've been in New York lately and they're ahead of Europe in many ways. I was impressed how their way of thinking is far ahead of us, by five years. Right now I'm in Israel and they're ten years behind Europe – they've a middle eastern approach. I see progress and people beginning to change how they think, so I feel something is happening.
I'm 37 now and when I was 17 it was different how you'd set your boundaries as a woman. There's an awareness and progress now, and that's why I'm still optimistic. Also, to see that we can go even further, which I saw in New York. I was in a bubble there, but still, it's normal to ask what pronouns you use? So many of the things that are still weird in Berlin, in Germany and Europe as a whole, it's normal there.
PR: Do you hope in time Bliss will be a look back at how things used to be?
HK: … It's always a look back, because society and morals are constantly changing. We can't read Hannah Arendt without questioning her, because some of her statements are deemed racist in today's context, similarly to Simone de Beauvoir. Even 50-year-old books by very smart people are outdated and that's why I think religion is weird - where people still stick to the morals of a 1,500-year-old Book like the Koran for example, without questioning the misogynist rudiments of it.
Hopefully we'll see this film in 20 years time and think, 'What?'
PR: Before to after, has the process of making this film changed you as a person?
HK: Yes, and that's the reason why you take the team and everyone on the journey, to be someone else afterwards. Why I love it so much is because you understand something in a deep way and you feel differently afterwards, not just intellectually but emotionally. All the people that ran this brothel were a part of the team, and they felt differently afterwards. It was the same thing with my first film.
I received some nice messages on Instagram from audiences all over the world, about how they somehow see it differently now. It wasn't hundreds of messages, but one here, and one there, and it's always about changing someone's perspective with the film. The women did it with their presence and it's beautiful.
PR: Speaking with Mark Cousins for his new documentary, The Story of Film: A New Generation, he discussed how filmmakers don't want to be defined by gender nor nationality. When we discuss women filmmakers, we often try to distinguish between the male and female gaze, but do women shoot scenes differently to men, for example sex scenes or emotional moments?
HK: I love the films of Lars von Trier, because his female characters are outstanding, but besides him, all the films I love are films by women filmmakers. For example, in Portrait of A Lady On Fire, the female gaze is very strong. In the sex scenes, the way the camera is used, it's a different way of telling a story. The films of von Trier are so different, and not just the sex scenes. It's a different gaze and I'm interested in that.
I think he's right, and at some point we will see it as a film from a person, but we're not there yet. There are female directors that copy the male gaze because that's the system they're brought up in. It's still in our visual memory and I sometimes copy the male gaze, but then I question why, because it's not mine, and then I try to change it.
Bliss is in cinemas now.

redpajama_set_name: RedPajamaCommonCrawl


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ECRI Institute, Welwyn Garden City, UK
******@***ecri.org.uk
http://ecri.org.uk/index.html
@ecri_institute
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HealthManagement, Volume 15 - Issue 4, 2015
Computed Tomography with Computer-Aided Detection for Lung Cancer Screening
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Several medical societies recommend annual lung cancer screening with low-dose computed tomography (LDCT) for certain individuals at high risk. However, the value of adding computer-aided detection to improve LDCT screening accuracy remains unclear.
Executive Summary: ECRI Perspectives
In June 2011, the U.S. National Cancer Institute's (NCI's) National Lung Screening Trial (n = 53,454 current or former heavy smokers aged 55 to 74) reported these findings regarding screening with lowdose helical computed tomography (LDCT) compared with chest x-ray: individuals screened with LDCT had a 15% to 20% lower risk of dying from lung cancer than individuals screened using standard chest x-ray (National Lung Screening Trial Research Team 2011). This means that about 3 fewer deaths per 1,000 people screened occurred in the LDCT group than in the chest x-ray group over a period of about 7 years of observation (17.6 per 1,000 vs. 20.7 per 1,000, respectively).
Study authors also reported that after 3 rounds of screening, on average, 24.2% of LDCT screens and 6.9% of chest x-rays were positive. These positive results usually led to additional testing.
The authors also reported that certain types of lung cancer were detected more often at the earliest stage by LDCT (adenocarcinomas and squamous cell carcinomas) than by chest x-ray. However, small-cell lung cancers, which are very aggressive, were not often detected at early stages by either method.
To improve LDCT screening accuracy, some developers have proposed using a class of pattern-recognition software called computeraided detection (CADe) to analyse radiologic images. The software is intended to identify patterns suggestive of disease and highlight them for radiologist review. Use of the technology requires additional staff time for interpretation and modestly increased data processing and storage capacity.
Adding CADe capability to a computed tomography (CT) system could cost up to $65,000 (€57,250) per license (ie, for each radiologist user), but additional reimbursement for its use is not available, even though CADe has been available since 2006. Two studies report that CADe adds up to 80 seconds for LDCT image review (Matsumoto et al. 2013; Bogoni et al. 2012); additional data storage requirements for CADe use are considered to be small to negligible.
Although several clinical guidelines recommend LDCT screening in the population defined in the NCI trial, they are silent on the role of CADe to improve LDCT screening accuracy (Detterbeck et al. 2013; Jaklitsch et al. 2012; Wender et al. 2013; American Lung Association Lung Cancer Screening Committee 2015; National Comprehensive Cancer Network (NCCN) 2015a; 2015b; Moyer VA; U.S. Preventive Services Task Force 2014)
A primary safety concern about using CADe for LDCT screening is the risk of increasing the rate of false-positive results. False positives often lead to additional testing and potential harm from unnecessary treatment from overdiagnosis of lung lesions unlikely to cause clinical symptoms.
Clinical trials are needed to determine whether CADe has an appropriate role for improving accuracy of LDCT for lung cancer screening. We identified one relevant ongoing study in China (Shanghai Changzheng Hospital), that may provide data in 2017 to further elucidate the role of CADe in LDCT screening.
Ratings and Rationales of Potential Impact
Note: The following ratings and comments reflect the opinions and consensus of an expert panel convened by ECRI Institute to review information on this topic.
Anticipated Utilisation: 1 (Expected to be used by 0% to 20% of eligible patients)
Clinical guidelines recommend low-dose computed tomography (LDCT) to screen high-risk patients for lung cancer; however, they are silent on enhancing LDCT with computer-aided detection (CADe) systems (Detterbeck et al. 2013; Jaklitsch et al. 2012; Wender et al. 2013; American Lung Association Lung Cancer Screening Committee 2015; National Comprehensive Cancer Network (NCCN) 2015a; 2015b; Moyer VA; U.S. Preventive Services Task Force 2014). Some manufacturers report that the slow initial adoption is unlikely to change without extra reimbursement or new clinical data showing that CADe improves outcomes or cost-effectiveness of LDCT. Over time, more radiologists might adopt software that automatically tracks changes to radiologistidentified lung nodules to facilitate lung cancer screening. However, that assumption would depend on ultimate patient demand for LDCT screening.
Estimated Adoption Status: 3 (Early adoption occurring – 0% to 25% of facilities that would be expected to adopt have adopted)
Before July 2012, the U.S. Food and Drug Administration (FDA) required companies to submit marketing applications for CADe software products under its premarket approval (PMA) application process. FDA granted Siemens AD (Munich, germany) a PMA for its syngo LungCAD product in October 2006 (United States Food and Drug Administration 2006). Since the change, FDA has not granted 510(k) marketing clearance to any software products that fully meet its definition of CADe: automatically identifying suspect lung nodules for radiologist review (ie, second reader mode).
Potential Health Impact: 2 (Expected to make a small improvement to patients' health and/or quality of life)
Few data are available to evaluate the potential effect of adding CADe to LDCT in lung cancer screening programmes. Several professional societies recommend LDCT lung cancer screening for certain older smokers and former smokers at highest risk of developing lung cancer. However, these guidelines generally do not address the addition of CADe to LDCT.
Potential Financial Impact: 2 (Expected to have a small financial impact)
Implementing CADe capability to a computed tomography (CT) system could cost up to $65,000 (€57,250) (PricePaid 2014), which is small relative to the overall cost of a CT system. Adding CADe to LDCT exams would likely lead to only a modest increase in data storage requirement. Additional reimbursement for adding CADe to LDCT exams is unlikely from third-party payers.
Potential Process and Infrastructure Impact: 2 (Expected to have a small process impact)
Adding CADe to LDCT exams is unlikely to cause major changes to existing lung cancer screening programmes. Implementing CADe for LDCT could incrementally increase radiologist workload by lengthening reading time per case. Increased data handling and storage requirements would likely be small. However, the potential downstream impact could be considerably greater if widespread use of CADe for LDCT lung cancer screening increases the number of false-positive findings, resulting in unnecessary additional testing and lung biopsies.
The full article including overview, references and trial information is available through ECRI's Health Technology Assessment Information Service (HTAIS).
About ECRI
ECRI Institute, a nonprofit organisation, dedicates itself to bringing the discipline of applied scientific research in healthcare to uncover he best approaches to improving patient care. As pioneers in this science for nearly 45 years, ECRI Institute marries experience and independence with the objectivity of evidence-based research.
ECRI 's focus is medical device technology, healthcare risk and quality management, and health technology assessment. It provides information services and technical assistance to more than 5,000 hospitals, healthcare organisations, ministries of health, government and planning agencies, voluntary sector organisations and accrediting agencies worldwide. Its databases (over 30), publications, information services and technical assistance services set the standard for the healthcare community.
More than 5,000 healthcare organisations worldwide rely on ECRI Institute's expertise in patient safety improvement, risk and quality management, healthcare processes, devices, procedures and drug technology. ECRI Institute is one of only a handful of organisations designated as both a Collaborating Centre of the World Health Organization and an evidence-based practice centre by the US Agency for healthcare research and quality in Europe. For more information, visit www.ecri.org.uk
American Lung Association Lung Cancer Screening Committee (2015)* Providing guidance on lung cancer screening to patients and physicians. Chicago, IL: American Lung Association. [Accessed: 20 October 2015] Available from lung. org/assets/documents/lung-cancer/lung-cancerscreening-report.pdf
Bogoni L, Ko JP, Alpert J et al. (2012) Impact of a computer-aided detection (CAD) system integrated into a picture archiving and communication system (PACS) on reader sensitivity and efficiency for the detection of lung nodules in thoracic CT exams. J Digit Imaging, 25(6): 771-81.
Detterbeck FC, Mazzone PJ, Naidich DP et al. (2013) Screening for lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest, 143(5 Suppl): e78S-92S.
Jaklitsch MT, Jacobson FL, Austin JH et al. (2012) The American Association for Thoracic Surgery guidelines for lung cancer screening using lowdose computed tomography scans for lung cancer survivors and other high-risk groups. J Thorac Cardiovasc Surg, 144(1): 33-8.
Matsumoto S, Ohno Y, Aoki T et al. (2013O Computer-aided detection of lung nodules on multidetector CT in concurrent-reader and secondreader modes: a comparative study. Eur J Radiol, 82(8): 1332-7.
Moyer VA; U.S. Preventive Services Task Force (2014) Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med, 160(5): 330-8.
National Comprehensive Cancer Network (NCCN) (2015a)* NCCN guidelines for patients®: non-small cell lung cancer. Version 1.2015 [slide set]. Fort Washington, PA: National Comprehensive Cancer Network (NCCN).[Accessed: 20 October 2015] Available from nccn.org/patients/guidelines/nscl
National Comprehensive Cancer Network (NCCN) (2015b)* NCCN clinical practice guidelines in oncology: lung cancer screening. V1.2016. Fort Washington, PA: National Comprehensive Cancer Network (NCCN). Accessed: 20 October 2015] Available from nccn.org/professionals/physician_ gls/pdf/lung_screening.pdf
National Lung Screening Trial Research Team (2011) Reduced lung-cancer mortality with lowdose computed tomographic screening. N Engl J Med, 365(5): 395-409.
PricePaid [database online] (2014). Plymouth Meeting, PA: ECRI Institute. [accessed 2014 Aug 27]. Syngo Imaging. Available from ecri.org.
Shanghai Changzheng Hospital. Screening for Early Lung Cancer in Shanghai, China. In: ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2015 October 19]. Available from clinicaltrials.gov/ show/NCT02185495
Wender R, Fontham ET, Barrera E Jr, et al. (2013) American Cancer Society lung cancer screening guidelines. CA Cancer J Clin, 63(2): 106-17.
* denotes citations updated by HealthManagement.org
CT, lung cancer, computed tomography, cancer screening
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Tags: Tea Party | Primary | DavidPerdue | Georgia
Rep. Westmoreland: Perdue's Blast of High School Grad Rival 'Stupid'
By Cathy Burke | Thursday, 03 April 2014 07:58 PM
Five-term Georgia Republican Rep. Lynn Westmoreland — who never graduated from college — Thursday blasted Senate hopeful David Perdue's "stupid" putdown of a tea party rival who never got a college degree.
Westmoreland said the businessman's jibe at former Georgia Secretary of State Karen Handel won't affect his choice in the crowded GOP primary May 20, Roll Call reported.
Westmoreland hasn't endorsed anyone running in the May 20 Republican primary to determine a candidate to run in the general election for the seat being vacated by two-term GOP Sen. Saxby Chambliss.
Michelle Nunn, daughter of former Democratic Sen. Sam Nunn, is expected to be the Republican's opponent in November.
"This just shows the different personalities," Westmoreland said. "I think it's stupid. I'm sure that's the way he feels, but I feel like you don't have to be a college [graduate with a] degree to be good at whatever you want to do. It's never hindered me."
Perdue has come under fire for suggesting Handel, who's also running for the GOP spot on the November ballot, isn't qualified to be in the Senate. In a speech in January, Perdue was videotaped saying: "I mean, there's a high school graduate in this race, OK?
"I'm sorry, but these issues are so much broader, so complex. There's only one candidate in this race that's ever lived outside the United States. How can you bring value to a debate about the economy unless you have any understanding about the free enterprise system and how — what it takes to compete in the global economy?"
Handel left a broken home at 17 and finished high school but not college.
Westmoreland said the nation's Founding Fathers "didn't say anything about a college education," Roll Call reported. "If he wants to put some qualifications on the office that are not in the Constitution, that's up to him."
GOP Faces Tight Senate Race Against Michelle Nunn in Georgia
Perdue Takes Lead in Georgia Senate Primary
Five-term Georgia Republican Rep. Lynn Westmoreland - who never graduated from college - Thursday blasted Senate hopeful David Perdue's stupid putdown of a tea party rival who never got a college degree. Westmoreland said the businessman's jibe at former Georgia...
Primary,DavidPerdue,Georgia,
Thursday, 03 April 2014 07:58 PM
Charles Cotton to Newsmax TV: NRA Bigger, Better in Texas
Do not believe New York's efforts to dissolve the National Rifle Association is due to money mismanagement or filing for . . .


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The Panama Papers
The Pegasus Project
The Pandora Papers
Main Navigation, Left Side
ivory trade
Report: To End Illegal Wildlife Trafficking, Follow The Money
Wildlife crime, from poaching to trafficking, remains a booming industry in East Africa. According to a recent report, it is a far more organized crime than previously imagined, and arrests need to be accompanied by financial investigations to truly dismantle the trade.
Nine Tonnes of Ivory Seized in Vietnam, World's Largest Haul
Vietnamese customs has seized over nine tonnes of ivory found in a container shipment from the Republic of Congo, thought to be the largest ivory seizure in recorded history.
Tanzania: Queen of Poaching Trade Sentenced to 15 Years
A Tanzanian Magistrate's Court sentenced on Tuesday Chinese businesswoman Yang Feng Glan, nicknamed "Ivory Queen," to 15 years in prison for running a large-scale smuggling operation which delivered ivory from the tusks of more than 350 elephants, worth US $6.4 million, to Asia.
Zimbabwe: "Gucci Grace" Suspected of Illegal Ivory Trade
Zimbabwe is investigating its extravagant former first lady's alleged ties to an ivory poaching and smuggling syndicate after a wildlife photographer discovered links to Grace Mugabe's friends, Al Jazeera reported Saturday.
Ivory Trade Investigator Stabbed to Death in Nairobi Home
Esmond Bradley Martin, an American conservationist who spent his life's work undercover, exposing the illegal ivory trade across the world, was found stabbed to death in his Nairobi home on Sunday.
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I've just finished reading Outliers, by Malcolm Gladwell. It's been a long time since I've done a book report (to a very patient but acerbic High School teacher) but that fact, combined with my need to go back through this excellent read and summarise for my own benefit, has pushed the task onto me.
Outliers begins with seven pages looking at the unusual health of the small country hamlet, Roseto Pennsylvania, the residents of which are mostly settled immigrants and their descendants from the same small country town in Italy. The townsfolk were discovered to have significantly lower incidences of a spectrum of health issues and social problems ranging from heart disease, ulcers, suicide, alcoholism, drug addiction and even crime in general than those found in other towns in the US – even small towns not far away, also settled by Italian immigrants. Gladwell refers to this unusual occurrence as an Outlier – an observation that is numerically distance from the rest of the data. The cause of Roseto was eventually discovered by a physician name Stewart Wolf, but only after a significant investigation that included historical research, interviews, various medical tests, diet and lifestyle analysis, geographical influences, even religion.
Sorry but you're going to have to read the book, besides – revealing the secret of Roseto is not the intent of Outliers – the investigatory process is. In Outliers Malcolm Gladwell examines the concept that there are members of our society – individuals, groups, nationalities both regional and cultural – that lie outside the statistical 'norm', and seeks to identify the true reason for the success (or lack of) these individuals and groups.
Along the way you'll read about the fundamental differences between East and West in work attitudes and the implications this has for our concept of educating our children. Aviation receives some special attention with a couple of accident investigations reviewed, including some expert commentary from an old friend of mine, Suren Ratwatte (how cool is that? Aviation is such a small world). You'll read about the steps Korean Airlines undertook to correct some cultural issues as they related to the flight deck at the turn of the century; about similar issues in a South American airline accident into JFK. The issues of authority gradient and uncertainty avoidance are explored and evaluated.
Having initially established (I would say hinted at considering the development it undergoes as the book progresses) his theme with Roseto, Malcolm Gladwell has this fabulous ability to progressively develop his case in a logical manner – and then you turn a page and embark on a journey of ten pages of fascinating but seemingly unrelated text. You get to the end, and without appearing to make any effort at all, the relevance of what you've just been reading smacks you in the eyes and the book continues on.
Outliers is a book of very readable book of facts, stories and hypotheses. The following points are not summaries of what you'll read in Outliers, but perhaps give you an idea of the range of what you'll encounter as you work your way through this fascinating book.
– A common thread that unites hockey players in the top league teams is Canada is their date of birth. Because of the annual cutoff date nature of player selection, a 12 month spread is achieved each year. Those older kids bring more experience and skills to their positions and therefore become the focus of better training and faster progression. Eventually this date based anomaly of recruitment becomes a self fulfilling prophesy – leaving behind players of equal or greater talent who have the miss-fortune of being born during the wrong part of the year.
– The role of very, very hard work and practice – the "Ten Thousand Hour Rule" cannot be overstated in may of the success stories around us. This is detailed in a discussion of Bill Gates, The Beatles, Classical Musicians and more.
– The merits of two opposing methods of raising children – "concerted cultivation" vs "accomplish of natural growth", which are essentially identified along class lines – and the impact that is likely to have on Outliers.
All of these and more make Outliers a fascinating read that will spur you off into many interesting areas. Like all of Malcolm Gladwell's books Outliers is an eclectic collection of connected stories that will keep your interest, and keep you thinking.


On Saturday, I made Onigiri to go with the Cabbage Nori Rolls I served to my family and our young guest. Though the rolls didn't contain any rice, Onigiri are virtually all rice. They're made by simply cupping sticky, hot sushi rice in your hand and pressing it into a triangle or other shape around a filling. I filled the round ones you see on the right side above with dried shiitake mushrooms that were re-hydrated and marinated briefly in miso and sesame oil (2 tbsp. water. 1 tsp. light miso, 1/8 tsp. sesame oil), and then rolled them in black sesame seeds. The vaguely triangle-shaped ones contained pieces of baked tofu and are wrapped in a piece of nori (wet it first).
First, make sure your rice is very sticky. I cooked mine as I usually do for sushi, and it wasn't quite sticky enough. I suggest adding a little more water than the package indicates.
Second, keep your hands wet as you mold and press the rice together. Sticky rice is, you know, sticky: it will cling to your hands and prevent you from making smooth shapes, but the water will keep it from sticking to you.
Finally, use a strongly-flavored food as the filling. Traditionally, umeboshi plums are used, and they have a very strong taste. My shiitake mushroom filling tasted much better than the tofu filling, which got lost in the middle of all that rice.
You can get more directions (and photos) for making onigiri at this site. Have fun!
Great advice on fillings, can't wait to try them!


The Butler County Prosecutor announced today the successful prosecution of Maria Roy. Defendant Roy, a 61-year old West Chester woman was convicted of Obstructing Official Business only after 15 minutes of jury deliberation.
On October 31, 2008, West Chester Police Officers were responding to a fight call on the Skinner property in West Chester where Defendant Roy resided. Upon arrival the officers found several individuals injured and underage drinking. Defendant Roy approached the officers and told them to leave. When she refused to comply with the officers, she was being handcuffed when a struggle ensued. As a result of the struggle, a West Chester Officers and Defendant Roy fell to the ground and both were injured.
"People should know not to interfere with the police when they are trying to respond to a call. Situations are often confusing without bystanders interjecting themselves into the situation and making it more dangerous. This 61-year old woman should know better than to physically intervene in a lawful investigation. We are glad no one was hurt and also thankful the jury saw through the defendant's ridiculous story that she was attacked by the police." Prosecutor Piper stated.


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InMed Pharmaceuticals, Inc. (CSE: IN) (OTCQB: IMLFF) is taking the challenges of the U.S. pharmaceutical industry head-on, and has broken new ground with an innovative, proprietary biosynthesis process that reliably creates pure cannabinoids.
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NetworkNewsWire Editorial Coverage:
The U.S. pharmaceutical industry is pocked with pitfalls that make it difficult for the development of cannabis-based drugs. To receive FDA approval, drug manufacturers must produce a consistent, pharmaceutical-grade product. Drug researchers with cannabis-based candidates are largely dependent on cannabis producers to access their drug raw materials. And therein lies the issue. The cannabis production sector has had its share of product recalls, and is saddled with pricey cost of commercial cultivation.
The roadblocks are considerable – from legal and execution standpoints – making these efforts not quite impossible but certainly, currently, difficult. Canada-based biopharmaceutical company InMed Pharmaceuticals, Inc. (CSE: IN) (OTCQB: IMLFF) (IMLFF Profile) is taking these challenges head-on, and has broken new ground with an innovative, proprietary biosynthesis process that reliably creates pure cannabinoids. This process is capable of making any of the 90+ individual cannabinoids, under strict quality control resulting in >95% purity with no pesticides, and in a consistent fashion – factors that current plant growing methods of production cannot accomplish. Biosynthesized product with consistently high purity and quality poses a considerable advantage over the medical marijuana used by companies like CanniMed Therapeutics, Inc. (TSX: CMED) (OTC: CMMDF) (FRA: 0GB), which cultivates its own cannabis for its product pipeline. Any biotech company seeking to develop cannabinoid-based drugs could benefit from InMed's unique approach. Currently, these biotech companies are dependent on growers like Aurora Cannabis, Inc. (TSX: ACB) (OTCQX: ACBFF), Canopy Growth Corp. (TSX: WEED) (OTC: TWMJF) and Aphria, Inc. (TSX: APH) (OTC: APHQF) to supply the raw flower or specific cannabinoid extracts needed, albeit only a few cannabinoids can be economically extracted from the plant. Such extracted product may not have the purity or consistency required to qualify as an FDA-approved pharmaceutical ingredient.
The extraction techniques from plant-growing operations are subject to high fluctuation in drug concentration, as flowers from the same marijuana plant display high fluctuations in drug composition. A key factor in receiving formal drug approval from regulatory authorities includes product consistency, which may be one reason the FDA, to date, has never approved a botanically-derived marijuana drug. A few synthetic cannabinoid-based drugs have, however, been approved by the FDA (http://nnw.fm/dyD4o), and experts believe marijuana's only future as a medicine in the U.S. is through its isolated, pure cannabinoid components and their synthetic counterparts.
While manufacturing synthetic cannabinoids is a potential means of sidestepping the various prohibitive aspects of agricultural cannabis production, many development efforts in this area have failed. Various companies have attempted to chemically synthesize cannabinoid compounds for pharmaceutical application, but the primary restrictive factor is the difficulty of duplicating these compounds in a way that makes them identical to the naturally-occurring ones. Even a slight variation in structure can mar the efficacy and safety of synthetic cannabinoid compounds, and, as with natural sourcing, the time drain, expense and tedium of the synthetic manufacturing process (along with the large quantities of chemical waste it creates) make it a problematic enterprise.
InMed Pharmaceuticals, Inc. (CSE: IN) (OTCQB: IMLFF) breakthrough biosynthesis process allows it to control the entire drug development process, in house – and without the inherent challenges of traditional agricultural cultivation methods.
Biosynthesis, or the process of producing complex molecules within living organisms or cells, is currently employed in various industrial applications, including using bacteria or yeast-based systems to produce pharmaceuticals. InMed's proprietary, pioneering approach to cannabinoid biosynthesis is truly a drug development game changer that has the potential to overcome FDA regulatory hurdles and bypass the other shortcomings associated with botanical cannabis cultivation. This process could open up several possibilities in terms of improving consistency and enabling biotechs to harness the potential of all cannabinoids.
InMed employs an E. coli-based expression system for manufacturing cannabinoids that has proven internally to be much more efficient and robust than other microbial platforms, and this system enables the high-yield manufacturing of all 90+ naturally occurring cannabinoids, combining the intrinsic safety and known effectiveness of natural drug structures with the control, quality and convenience of lab-based manufacturing.
Employing this exclusive process in a controlled lab setting, scientists at InMed are able to create cannabinoid compounds that are identical to those that occur naturally while eliminating problems associated with inconsistency and contamination from pesticides.
Aside from inconsistency issues, another stumbling block on the botanical marijuana side is the difficulty of extracting compounds from the cannabis plant in adequate amounts and purities to pharmaceutically test them. Natural sourcing of most cannabinoid compounds is very time-consuming, difficult, expensive, inconsistent (as previously mentioned) and low-yielding. The natural sourcing process only yields about two or three cannabinoids that can be derived in adequate quantities for research, while the rest of the cannabinoid compounds only manifest themselves in trace amounts that are not accessible through extraction from plants.
InMed's biosynthesis method is can reduce the costs and time required to manufacture cannabinoid compounds that are pharmaceutically active. It is also capable of manufacturing not just some but all naturally occurring cannabinoids.
InMed is effectively bringing cannabis-based drug development into a new era, shaking up the established, agriculture-based mentality of "plant, grow, harvest, extract and purify" that has long been the norm in the area of manufacturing raw cannabinoid material.
The benefits of InMed's novel approach are several and include:
Substantial cost savings in comparison to traditional agricultural methods
Easier path to scale-up and systems optimization
Superior production, purification, quality control as compared to agricultural approaches and better structural integrity in comparison with other chemical manufacturing practices
Ability to access minor cannabinoids for which plant-based extraction methods are currently economically unfeasible
InMed recently announced a provisional patent application filing for this proprietary cannabinoid manufacturing biosynthesis program—the first of many to come (http://nnw.fm/Z30dH). Once this inaugural patent application is converted into an international Patent Cooperation Treaty (PCT) application and is pursued on a global scale in important jurisdictions, InMed will have significant commercial protection for its biosynthesis program. The company plans to actively convert this initial patent filling and subsequent provisional patents into national-stage filings in all major commercial jurisdictions.
In terms of InMed's internal drug development abilities, a recent press release from the company (http://nnw.fm/EZ0Gk) validates its capability to conduct a broad array of drug development activities that are crucial to obtaining eventual FDA approval for cannabinoid-based drugs. As discussed in the press release, InMed has successfully and consistently biosynthesized a pharmaceutical-grade cannabinoid using its novel E. coli-based system; packaged the cannabinoid as a nanoparticle; formulated a cannabinoid drug candidate into a novel, tissue-specific delivery vehicle; and confirmed drug delivery and diffusion into a target tissue.
The press release announced the results of a study co-sponsored by InMed and the University of British Columbia, which is, to the company's knowledge, the very first study to ever report hydrogel-mediated cannabinoid nanoparticle delivery to the eye. This resulted in bolstered drug uptake through the cornea and lens. Ordinary ocular formulations, like eyedrops, are almost instantly washed away following administration because of blinking. In the study, however, InMed's proprietary hydrogel delivery method demonstrated distinctive rheological characteristics that enabled it to form a thin, uniform coating over the cornea through blinking. The gel-like "lens" that was created over the cornea held the drug in place, allowing trans-corneal absorption of the drug to occur. The drug was then able to diffuse within the eye. The overall drug delivery achieved through this hydrogel nanoparticle formulation was three times higher than the control formulation.
"Importantly, this study offers further validation of InMed's capabilities in moving the science of cannabinoid pharmaceuticals forward," InMed President and CEO Eric A. Adams said in the press release. "Results like this, combined with our expanding patent portfolio and list of publications, on-going R&D, and renowned scientific team and collaborators demonstrates our depth of know-how and supports our trajectory to becoming an industry leader."
InMed's drug pipeline – developed using its biosynthesis process – currently includes two products: INM-085 for the treatment of glaucoma and INM-750 for the treatment of epidermolysis bullosa. This pipeline is founded on the company's ability to produce its own pharmaceutical-grade cannabinoids for use in its products, which enables InMed to manage the entire drug development cycle. Using bioinformatics—a proprietary, computer-based drug/disease targeting platform developed by InMed—the company is also able to identify novel cannabinoids that could be utilized in targeting specific diseases. InMed can then biosynthesize those cannabinoids for product development.
This groundbreaking work is not only helping InMed toward overcoming drug approval barriers but could also have a huge impact on the efforts of other drug development companies within the cannabis sector that are striving to create cannabinoid-based therapies to treat various medical conditions.
InMed's ability to consistently manufacture pharmaceutical-grade cannabinoids demonstrates the company's favorable cost-savings and quality aspects compared with traditional cannabis producers. While such producers are working to meet the demands of biotech companies, which are, in turn, striving to satisfy regulatory standards, these producers may face many challenges.
One of the biggest marijuana growers in the world is Canopy Growth Corp. (TWMJF), which operates more than half-a-million square feet of production space. Despite its size and market domination, Canopy is dependent on significant capital and large parcels of land and is also handicapped by huge operating costs and the typical quality control issues seen with agricultural operations.
Another large producer, Aurora Cannabis (TSX: ACB) (OTCQX: ACBFF) operates a 55,200-square-foot cultivation and harvesting facility in the Rocky Mountains, and the company is in the process of adding an additional 840,000 square feet across two other sites in Canada. Aurora owns a 19.9% stake in the first Australian company licensed to cultivate and conduct research on medical cannabis, and it owns a leading Germany-based wholesale importer, exporter and distributor of medical cannabis. In January 2017, Aurora announced a Type II recall of its products, as some of its marketed offerings contained "residual levels of myclobutanil and/or bifenazate that exceed any of the levels permitted in food production for these two pesticides."
Aphria (TSX: APH) (OTC: APHQF), a producer of medical-grade cannabis as well as capsules, vaporizers and orally-administered cannabis oil droppers, initiated a Type III recall of its own in March 2017 due to mislabeling of the delta-9-tetrahydrocannabidiol (THC) content of some of its products.
The obstacles faced by cannabis cultivators and the subsequent disadvantages to the drug development companies that rely on them attest to the importance of the revolutionary biosynthesis process InMed has pioneered. Despite continued federal restrictions on cannabis research and cultivation in the U.S., InMed's innovations have the potential to help biotechs clear the hurdles and create biosynthesized cannabinoid-based pharmaceutical products of unparalleled consistency and quality required to meet the FDA's standards. Additionally, the ability to manufacture every type of cannabinoid, which is made possible by InMed's process, is poised to be one of the most exciting innovations the medical cannabis sector has seen.
For more information on InMed Pharmaceuticals, please visit: InMed Pharmaceuticals, Inc. (CSE: IN) (OTCQB: IMLFF)
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This news release/advertorial is a commercial advertisement and is for general information purposes only. We are engaged in the business of marketing and advertising companies for monetary compensation. Never invest in any stock featured on our site or emails unless you can afford to lose your entire investment. It is possible that a viewer's entire investment may be lost or impaired due to the speculative nature of the companies profiled. Remember, never invest in any security of a company profiled or discussed on this website unless you can afford to lose your entire investment. Also, investing in small-cap and micro-cap securities is highly speculative and carries an extremely high degree of risk. This website makes no recommendation that the securities of the companies profiled or discussed on this website should be purchased, sold or held by viewers that learn of the profiled companies through our website. Compensation: A thirty-six-thousand-dollar investor relations budget is being managed by The Seed Investor. Any funds leftover after expenses for research, overhead, advertising and public relations related to InMed Pharmaceuticals Inc. (ticker symbol (CSE: IN; OTCQB: IMLFF) will be considered profit. The Seed Investor and/or entities related to The Seed Investor hold shares in (CSE: IN; OTCQB: IMLFF) and intend to sell those shares. Please review all investment decisions with a licensed investment advisor.


Description: In Examined Life, filmmaker Astra Taylor accompanies some of today's most influential thinkers on a series of unique excursions through places and spaces that hold particular resonance for them and their ideas.
Peter Singer's thoughts on the ethics of consumption are amplified against the backdrop of Fifth Avenue's posh boutiques. Slavoj Zizek questions current beliefs about the environment while sifting through a garbage dump. Michael Hardt ponders the nature of revolution while surrounded by symbols of wealth and leisure.
Judith Butler and a friend stroll through San Francisco's Mission District questioning our culture's fixation on individualism. And while driving through Manhattan, Cornel West—perhaps America's best-known public intellectual—compares philosophy to jazz and blues, reminding us how intense and invigorating a life of the mind can be.


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video Clip From 0 Redemption Walmart Tosh Web Comedy Banned vqYwx6O It says much about the incoming Republican legislative leaders that one of their top priorities is to make it harder for people to vote.


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IHD-TIHV-Report: Human right violations in Turkey and Kurdistan in 2015
Severe human right violations by the Turkish state
The Human Rights Association (IHD) and the Human Rights Foundation of Turkey (TIHV), published the 2015 human rights violation report that was prepared during the 10-17 December Week of Human Rights. Ozturk Turkdogan, the general president of IHD who disclosed the report declared "From the perspective of human rights there is a demand that needs to be met from Turkey. That is to urgently establish peace. When peace is not ensured the right to live is not protected, when the right to live is being abused it is impossible to speak of other human rights". Moreover Turkdogan, said that since there was no intervention in the human right violations conducted in 2015, the United Nations' system has collapsed.
The end of the Kurdish-Turkish Peace Process increased the violations
Severe cases of human right violations were experienced during 2015: In Diyarbakir (5 dead, tens injured) , in Suruc (33 dead, tens injured) and in the Ankara massacre (100 dead, hundreds injured). With the end of the Kurdish-Turkish Peace Process by the President of Turkey Recep T Erdogan, hundreds of people were shot in the streets by the law enforcement units, in the renewed conflicts. Tens of times civilians and the PKK were bombed on Iraq grounds. Curfew was declared in tens of Kurdish towns within Turkey. During the curfew period water and electric outages, lack of basic food supply was experienced. Medication and treatment to those injured by the attacks were not allowed by the police itself on the ground of the incident, whereas the dead could not be buried due to curfew prohibitions. During the blockade of towns and neighborhoods by the law enforcements units civilian youths, women, elderly and children were massacred. Journalists were arrested and freedom of press was violated. The refugees in Turkey are facing dramatic circumstances.
The report is alarming
With AKP's realization of the oppressive "Internal Security Law" there was an increase of the human rights violations between the 1st of January and the 5th of December of 2015.
The data from IHD and TIHV are the following:
173 fatalities and 226 injured were the result of extrajudicial executions, random shooting or shooting of civilians that failed to comply with the law enforcement unit's orders.
There were 135 incidents involving deaths and 191 events involving injuries.
As a result of the suicide attacks, 5 died in Diyarbakir, 33 died in Suruc, the Ankara attack on the 10th October had 100 fatalities. The above three suicide bombs resulted in 138 dead and 929 injured.
Four people died while in custody
Murders committed by unknown perpetrators have resulted in the death of nineteen people
A minimum of 28 people have died from various reasons while imprisoned
33 soldiers have died under suspicious conditions while in military conscription
5 people have died and 22 have been injured as a result of unknown perpetrator bomb or mine explosions
As a result of the conflict, soldiers, police officers and paramilitary ranger in the total number of 171 have lost their lives. Along the same lines 195 militants and 157 civilians died, raising the total number of fatalities to 523 people
255 women have died as a result of male violence until the 23rd of November 2015
Four lives were lost as a result of hate crimes, racist attacks and lynching
Work accidents/murders have cost the death of 1593 workers until the 1st of December
A minimum of 16 asylum seekers and refugees have lost their lives while crossing the borders and 160 of them were injured
1433 people were tortured while held in custody
According to Human Rights Foundation of Turkey 1 million 299 thousand 61 people were affected from the curfew which was declared 52 times (16 August to 12 December 2015) in 7 different provinces and 17 districts.
 Diyarbakir: Curfew was declared 31 times in 8 districts
Lice – 7 times (26.427 people live according to the 2014 census)
Silvan – 6 times (86,663 people live according to the 2014 census)
Sur – 6 times (121,75 people live according to the 2014 census)
Bismil – 4 times (112,461 people live according to the 2014 census)
Hani – 4 times (32,413 people live according to the 2014 census)
* Yenişehir – 1 time (2014 nüfus sayımına göre 206,534 kişi yaşıyor)
* Dicle – 1 time (40,33 people live according to the 2014 census)
* Hazro – 2 times (17,54 people live according to the 2014 census)
 Mardin: Curfew was declared 9 times in 3 districts
Nusaybin – 5 times (116,68 people live according to the 2014 census)
Dargeçit – 2 times (28,601 people live according to the 2014 census)
Derik – 2 times (61,32 people live according to the 2014 census)
 Şırnak: Curfew was declared 5 times in 2 districts
Cizre – 4 times (132, 857 people live according to the 2014 census)
Silopi – 1 time (121,11 people live according to the 2014 census)
 Hakkari: Curfew was declared 4 times in 1 district
Yüksekova – 4 times (117,44 people live according to the 2014 census)
Turkey continues its ill treatment and torture The torture continues under the supervision of the security forces in detention centers, prisons and in military barracks. Moreover, with the excessive and disproportionate intervention of law enforcement units, officers commit torture and ill treatment against the participants in demonstrations publicly in the streets. With the Kurdish problem peaking the conflicts have increased and so have the custody procedures, however not implementing protection of human rights, torture and ill treatment while in custody have been legitimized. During the first 11 months of 2015 560 people reported to have suffered torture, 347 of whom were tortured or ill-treated within the current year. According to the data acquired by the Human Rights Association (IHD) during the first 11 months of 2015 433 reported to be tortured while under custody but outside detention centers. Impunity is still the greatest obstacle in the struggle against torture.
The violations in the context of the Kurdish problem are severe
The unlawful curfews that have been implemented in the Kurdish provinces and districts have left the people living in those regions devoid of water, electric, food supply and health services. The right to share information and communicate was restricted. The fact that the security forces employed special warfare methods and the numerous fatalities of civilian youths, elderly, women and children is worrisome. Because of the afore mentioned extraordinary war situation that was granted continuity in cities and towns, the economic and social life has completely collapsed.
According to the report of IHD and THIV:
In 2015 523 people died of whom 171 were soldiers, police officers and civil rangers, 195 were militants and 157 were civilians.
553 people were injured of whom 338 belonged to the security forces, 145 were militants and 70 were civilians.
6744 people were detained and 285 were arrested
Political genocide operations continue
17 councilors have been arrested, 9 of them convicted and 15 dismissed from duty. The number of civil rangers has increased. According to KCK investigations, from the operations against HDP/DBP and HDK, 6744 people have been taken into custody and 1285 have been arrested.
Freedom of thought and expression severely opressed
Access to 105958 websites was prohibited. 30 journalist are still in prison. Most recently, two journalist from the Nokta magazine were arrested. The number of prohibited websites in 2015 was 105958, whereas in 2014 it was 40773 and in 2013 it was 35001. The increase is worrisome.
Violence against Kurds and dissidents
Turkdogan highlights the fact that in 2015, 432 party offices were attacked, out of those 417 were HDP offices, 11 were belonged to AKP and 4 were CHP offices, furthermore he adds: "police forces this year attacked peaceful demonstrations with water cannons, chemical weapons, plastic and real bullets resorting to excessive and disproportionate violence. Different social groups such as women, LGBT, Kurdish, Alevi people and workers were subjected to violence without exception. As a result of these brutal attacks 210 people have been injured, 3377 have been take to custody and 201 people have been arrested. In total 256 organized events were forbidden.
The F type Prison of Imrali should be closed immediately
Turkdogan reminded that when AKP came in to the power the number of prisoners was 59429, according to the most recent information from the Ministry of Justice the current amount of prisoners is 164461.
The number of children detainees and convicts has reached 2165.
As a result of torture, suicide, ill treatment, accidents, negligence, disease, conflicts between prisoners etc. a minimum 28 people lost their life.
Additionally, the 22nd January 2007 (45/1) legislation of the Ministry of Justice prescribing that 10 prisoners should socialise for 10 hours each week is still not implemented effectively.
The F type Prison of Imrali, where isolation is applied very frequently, should be closed immediately.
282 women have lost their life
During the first 11 months of 2015 in all work places 1593 workers died as result of work accidents/murders. Turkey, ranks 23rd in the list of countries whose carbon gas emissions affect global climate change. Turkdogan, the general president of IHD, who addressed the following issue as well, drew attention to the fact that during the first 11 months of 2015, 282 women have lost their life, 367 women have been injured and 132 women were raped and abused.
Without peace and an end to Erdogan's dictatorship the right to life cannot be protected
Even though 2015 is the 68th anniversary of the Universal Declaration of Human Rights, with Kurds being primarily the target, all democratic and oppressed social groups are being tortured and suppressed. Everyone who is opposing Erdogan's authority and AKP's fascist rule is under serious threat. Credit has been given to Turkey and its government by the European Union regarding Turkey's accession to the EU, regardless that Turkey has been violating all democratic criteria. It is still receiving EU's support. It is not understandable why the European countries do not take action against the Turkish government that is cooperating with a barbaric force like ISIS, which is an enemy of all humanity.
Not taking any action against the AKP government that is committing crimes against the Kurdish people daily and remaining silent is unethical.
We are calling everyone to participate in the struggle to put an end to the isolation that the Turkish state is imposing on the Kurdish Leader and to initiate the Kurdish-Turkish peace process. Even though many countries and international associations have called for a peace process, none of them took action when Turkey failed to materialize the call.
We call all the democratic organizations and international foundations to stand against AKP and Erdogan's dictatorship and support the peoples resisting for democracy. As long as peace for the Kurdish people is not ensured and an end is not put to Turkey's policies in Syria and Iraq, EU countries are facing a threat. ISIS, that is taking advantage of Turkey's approach in the Middle East, is bloodsheding in the EU. To stop ISIS, the support that Turkey is giving to ISIS needs to be halted and condemned.


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(Redirected from Istari)
"I oughtn't to interrupt you, I know. [...] You are very busy, I'm sure." — Mr. Parish
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The Order of Wizards
"The Istari" by Angel Falto
Other names Heren Istarion, Istari (Q), Ithryn (S), Five Wizards[1]
Date founded c. T.A. 1000
Founder Manwë
Purpose The help the Free peoples to resist Sauron
Notable members Saruman, Gandalf, Radagast, Alatar, Pallando
Location Orthanc (Saruman)
Rhosgobel (Radagast)
Rhûn and Harad (Blue Wizards)
Disbanded T.A. 3021
Notable for Bringing about the final defeat of Sauron (mostly by Gandalf)
Gallery Images of The Order of Wizards
"Do not meddle in the affairs of wizards, for they are subtle and quick to anger."
― Gildor Inglorion in The Fellowship of the Ring, "Three is Company"
The Order of Wizards (Q. Heren Istarion) was the title assigned to five Maiar in the Third Age of Middle-earth. The wizards were commonly known as the Istari (Quenya) and the Ithryn (Sindarin).[2]
2 Etymology
4 Other versions of the legendarium
5 Other fiction
Gandalf by John Howe
Among Men it was initially assumed that the wizards were also men who by long and secret study had acquired great knowledge of lore and arts. However, as the Third Age passed it was marked that the wizards did not die and so Men began to believe that they were of Elven-kind. However, None except Elrond, Círdan, and Galadriel knew that, in actuality, the wizards, were Maiar, vassals of the Valar. These were sent by the Valar to help and assist the peoples of Middle-earth against Sauron as he gathered his forces during the Third Age.[2]
The five known Istari were:
Curumo, a Maia of Aulë
Olórin, a Maia of Manwë and Varda (held by Círdan the Shipwright to be the wisest of the Order).[3][note 1]
Aiwendil, a Maia of Yavanna
Alatar and Pallando, both Maiar of Oromë. Alatar and Pallando, also known as Ithryn Luin, the "Blue Wizards," went into the East and South, and do not appear in any of the main tales of Middle-earth.
In the northwest of Middle-earth Curumo became known as Saruman to Men and Curunír to Elves; Olórin was known as Gandalf to Men and Mithrandir to Elves; while Aiwendil became known as Radagast.
The Heren Istarion had been created in Valinor. A council of the Valar was called by Manwë which resolved to send three emissaries. Initially only Curumo (Saruman), chosen by Aulë, and Alatar, chosen by Oromë, stepped forward. Manwë then asked for Olórin (Gandalf) and commanded him to go. Curumo took Aiwendil (Radagast) with him because Yavanna begged him to do so and Alatar took along his friend Pallando.[4]
Cirdan witnessed the arrival of the Order in Middle-earth around the year c. T.A. 1000 (though the Blue Wizards may have arrived much earlier). Their "mission" was to advise and persuade Men and Elves to resist Sauron. Each wizard was assigned a colour for his clothes. The wizard in white was Saruman, regarded by all as leader of the order, with white being indicative of the chief. The two in sea-blue robes that travelled to the East and South were Alatar and Pallando. Together, the two of them were known as the Blue Wizards. The one in brown was Radagast and the one in grey was Gandalf, seemingly the oldest and the least of the Order.[2] It is not known if the colour had any special meaning concerning their rank, abilities or nature.
They were clothed in the bodies of old men, restricting their powers so that they would only assist the peoples of Middle-earth and not seek domination like Sauron had, who was also a Maia. They were charged by the Valar to assist the people of Middle-earth through persuasion and encouragement, not force or fear. By inhabiting the bodies of Men they also became susceptible to all of the weaknesses of a physical body: they felt hunger, pain, greed, sorrow, joy, and all other emotions and pains of Men.[2]
They were immortal, and they aged only very slowly.[2] However, their bodies could be killed:[2] Gandalf was mortally wounded in his duel with the Balrog of Moria, and only through the intervention of Ilúvatar himself was he restored to his body.
Very few of Middle-earth's inhabitants knew who the Wizards really were; the Istari did not share this information. Most believed they were Elves or wise Men (Gandalf represents this interpretation, meaning Wand-elf, because the Men who gave him the nickname believed he was an Elf). They attracted few questions due to their gentle nature and dislike of direct interference with other people's affairs. In spite of their specific and unambiguous goal, the Wizards were nevertheless capable of mortal feelings, thus Gandalf felt great affection for the Hobbits. On the other hand, they could feel negative mortal emotions like greed, jealousy, and lust for power. Saruman himself fell victim to these emotions, and it is hinted in an essay in Unfinished Tales that the Blue Wizards (see below) may have also fallen prey to these temptations during their journeys in the East.
Saruman was originally gifted with the greatest power of the five Istari and was named the head of the White Council, a group of the Wise in opposition to Sauron. In T.A. 2759, he was invited by the rulers of Gondor and Rohan to settle in Isengard and the impenetrable tower of Orthanc. Saruman was learned in the lore of the Rings of Power, gradually becoming corrupted by the desire for the Rings and by Sauron's direct influence on him through the palantír of Orthanc. Eventually he became ensnared in Sauron's power, and assisted him in the War of the Ring until he was defeated by the Ents and Gandalf, who broke his staff and cast him out of the White Council. Saruman's death came at the hands of his servant Wormtongue in The Shire, after the destruction of the One Ring. His spirit was then dispersed by a wind from the West, becoming similar to Sauron in his destruction.
When Saruman fell to the temptation of the Ring, and after the defeat of the Balrog of Moria, Gandalf was reborn and given the title of Gandalf the White. Gandalf, who had originally been nominated for leadership of the White Council by the Elf-Lady Galadriel, assumed leadership both of the White Council and the Order of the Istari. He then cast Saruman from the order and led the West to victory over Sauron, advising the Ringbearer Frodo and the new king of Gondor Aragorn Elessar. After the defeat of Sauron and Saruman, Gandalf traveled west across the Sea with the Ringbearers, revealing that he himself was the bearer of Narya, one of the Elven Rings of Power.
Radagast stayed true to his mission for a while, even serving as a messenger to Gandalf from Saruman, convincing Gandalf to meet with Saruman. He also instructed the birds in his service to assist Saruman and Gandalf. Radagast dwelt at Rhosgobel near the borders of Mirkwood. Eventually, Radagast is said to have become enamoured of the beasts and birds and to have ultimately failed to complete his mission. Later writings are less critical of Radagast, arguing that he did not fail at his mission as much as simply choose a tactic - working with the animal world - that ultimately proved less directly effective than working with Men and Elves.
The Blue Wizards went into the East and South and do not come into the tales of north-western Middle-earth. It is sometimes thought that the Blue Wizards also failed in their mission and fell to the temptations that had corrupted Saruman; it is said that their fall gave rise to magical cults in the East and South.[5] However, other writings again suggest otherwise, even that the Blue Wizards possibly succeeded in their mission, and that the victories of the West would have been impossible without their influence in the East and South.[1]
The Order of Wizards came to an end with the passing of Sauron. Saruman died in Middle-earth after Gríma Wormtongue had cut his throat. It is probable that the spirit of Saruman was not allowed to return to the West, because the grey mist that rose from his body and that lingered as a pale shrouded figure dissolved into nothing when a cold wind came from the West.[6] Gandalf, who remained true to the mission of the Order, departed from Middle-earth in 3021.[7] The fate of the other three wizards who landed in the North is unknown.[2]
The name Wizards, which means "wise" (in the sense of "Wise Men"[8]) rather than "sorcerer" or "magician"[9][10] is a translation of the Quenya name Istari.[11]
Other names[edit]
The Quenya name Istari (singular Istar) means "ones who know"[12] or "those who know".[13][10] Helge Fauskanger suggests that it is a combination of the verb ista- ("to know") and the agentive ending -r(o).[14]
The Sindarin name Ithryn (singular Ithron) means "wizards".[15]
Other versions of the legendarium[edit]
In Gnomish, one of Tolkien's early conceptions of an Elven language, the word for "wizard" is curug (and "witch" is curus). An alternative word is thothweg, also translated as "wizard".[16]
In The Hobbit, while no mention is made of an Order of Wizards, Gandalf tells Beorn that Radagast is his "cousin".[17] In the Unfinished Tales it is said that the wizards appeared in Middle-earth about 1000,[2] but in The Peoples of Middle-earth a rough note by J.R.R. Tolkien said that the Blue Wizards (Alatar and Pallando, or Morinehtar and Rómestámo) came much earlier in the Second Age.[18] Christopher Tolkien stated that much of the writings about the Istari are rapid jottings and often illegible.[2]
Other fiction[edit]
In Tolkien's Roverandom, an old wizard, Artaxerxes, uses a spell to bewitch Rover, a dog, into a toy for biting him.
2001-03: The Lord of the Rings (film series):
In Peter Jackson's film version of The Lord of the Rings, two of the five Wizards (Saruman and Gandalf) were portrayed and featured heavily in the film trilogy (as the characters do in the books.)
2012-14: The Hobbit (film series):
Although Radagast has a small role in The Lord of the Rings, his role was omitted in Peter Jackson's film trilogy. However, Radagast had a substantial supporting role in The Hobbit films, and Saruman had a brief appearance. The Blue Wizards are also referenced in passing by Gandalf, although they make no appearance.
↑ Gandalf does, however, refer to Saruman as "the wisest of our Order" during the Council of Elrond. This could be an inconsistency, but could also be humility on Gandalf's part.
↑ 1.0 1.1 J.R.R. Tolkien, Christopher Tolkien (ed.), The Peoples of Middle-earth, "XIII. Last Writings", The Five Wizards, second note on the reverse of a page probably from 1972
↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 J.R.R. Tolkien, Christopher Tolkien (ed.), Unfinished Tales, "The Istari", the essay on the Istari
↑ J.R.R. Tolkien, Christopher Tolkien (ed.), The Silmarillion, "Valaquenta: Of the Maiar"
↑ J.R.R. Tolkien, Christopher Tolkien (ed.), Unfinished Tales, "The Istari", sketch of a narrative about a council of the Valar
↑ J.R.R. Tolkien, Christopher Tolkien (ed.), Unfinished Tales, "The Istari", "Notes", note 3 referring to a letter by J.R.R. Tolkien from 1958
↑ J.R.R. Tolkien, The Lord of the Rings, The Return of the King, "The Scouring of the Shire", p. 1020
↑ J.R.R. Tolkien, The Lord of the Rings, The Return of the King, "The Grey Havens", p. 1030
↑ J.R.R. Tolkien, Christopher Tolkien (ed.), The Peoples of Middle-earth, "VIII. The Tale of Years of the Third Age", manuscript T4, entry c. 1000
↑ J.R.R. Tolkien; Humphrey Carpenter, Christopher Tolkien (eds.), The Letters of J.R.R. Tolkien, Note 24 to Letter 131, (undated, written late 1951)
↑ 10.0 10.1 J.R.R. Tolkien; Humphrey Carpenter, Christopher Tolkien (eds.), The Letters of J.R.R. Tolkien, Letter 156, (dated 4 November 1954)
↑ J.R.R. Tolkien, Christopher Tolkien (ed.), Unfinished Tales, "The Istari"
↑ J.R.R. Tolkien, "Words, Phrases and Passages in Various Tongues in The Lord of the Rings", in Parma Eldalamberon XVII (edited by Christopher Gilson), entry Q Istari, p. 119
↑ J.R.R. Tolkien, Christopher Tolkien (ed.), The Peoples of Middle-earth, "XI. The Shibboleth of Fëanor", "Notes", p. 360, note 30
↑ Helge Fauskanger, "Quenya Affixes", Ardalambion (accessed 19 November 2022)
↑ Paul Strack, "S. Ithron n.", Eldamo - An Elvish Lexicon (accessed 19 November 2022)
↑ J.R.R. Tolkien, "I-Lam na-Ngoldathon: The Grammar and Lexicon of the Gnomish Tongue", in Parma Eldalamberon XI (edited by Christopher Gilson, Arden R. Smith, and Patrick H. Wynne), pp. 27, 73
↑ J.R.R. Tolkien, The Hobbit, "Queer Lodgings"
↑ J.R.R. Tolkien, Christopher Tolkien (ed.), The Peoples of Middle-earth, "XIII. Last Writings", The Five Wizards, pp. 384-5
Valar Lords Manwë · Ulmo · Aulë · Oromë · Mandos · Irmo · Tulkas · Melkor
Queens Varda · Yavanna · Nienna · Estë · Vairë · Vána · Nessa
Maiar Arien · Eönwë · Ilmarë · Melian · Ossë · Salmar · Tilion · Uinen
Wizards Saruman · Gandalf · Radagast · Blue Wizards
Úmaiar Sauron · Balrogs (Gothmog · Durin's Bane) · Boldogs
Concepts and locations Almaren · Aratar (indicated in italics) · Creation of the Ainur · Fana · Máhanaxar · Music · Second Music · Timeless Halls · Valarin · Valinor · Valmar
Retrieved from "https://tolkiengateway.net/w/index.php?title=Wizards&oldid=362084"


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Mission product Kyle Claggett's first career individual victory highlighted the University of the Fraser Valley men's golf team's seventh straight team triumph at the Walla Walla University Invitational.
Claggett was metronome-like in his consistency, carding rounds of 75, 74 and 74 to finish at seven over par. That left him three strokes clear of teammates Ben Whiton and Connor O'Dell (both +10). The University of Idaho's Cole Chrisman (+11) and the College of Idaho's Chris Carew (+13) were fourth and fifth, respectively, and UFV's Daniel Campbell and Halen Davis tied for sixth at +14.


text:
Dr. John Tamerius Senior Vice President, Strategic & External Affairs, Quidel Corporation
John Tamerius graduated from the Univ. of Washington with a Ph.D. in Microbiology and Immunology. He performed graduate and postdoctoral research in tumor immunology at the Fred Hutchinson Cancer Center before joining the Scripps Clinic and Research Foundation (San Diego) as a Research Associate in the Dept. of Molecular Immunology; here he studied inflammation, the complement system, and was a National Arthritis Fellow. He co-founded Cytotech where he led the development of 9 FDA-cleared products, approx. 100 research products and five research-use-only kits for studies of immune complexes, inflammation, and the complement system.
That company was acquired by Quidel Corporation in 1989, where during his on-going tenure there, he has held several important leadership roles, including VP of R&D, General Manager of Quidel's northern California division, and SrVP of Clinical & Regulatory Affairs. He now serves as SrVP of Strategic & External Affairs. While head of R&D he was in charge of the development of the first CLIA-waived, lateral flow test for influenza (QuickVue).
More recently, he has worked closely with the teams that have developed several rapid antigen detection tests for the SARS-CoV-2 virus–the most recent of which is the QuickVue At-home OTC COVID-19 Assay.


Passengers arriving to Voronezh International Airport are taken to the terminal building by comfortable apron buses. You should pay attention to the fact that baggage claim procedures for domestic and international flights vary.
Domestic airline passengers are taken to baggage claim area for domestic flights by bus. The information about baggage from arriving flights is shown on a display panel overhead a belt conveyor. Baggage will be delivered within 20 minutes after arrival. Over-sized baggage is delivered separately. Before entering the city you must present your baggage tags to an agent at the baggage claim area.
In case you have not received your baggage, or detected it damaged, you should report to an agent at the baggage claim area. An agent will help you to fill in a form of baggage search.
You can collect unclaimed, lost and mishandles baggage at temporary storage or an airport storage room.
In some cases, transport police officers may request your luggage for post-flight inspection. The main purpose is to prevent and intercept smuggling and distribution of weapons, ammunition, drugs, explosive articles and toxic substances from criminogenic regions. Inspection is carried out in accordance with Russian Federation Law No. 3 On Police, dated 7.02.2011.
International airline passengers are taken to the international arrivals area. Thereafter, you must go upstairs to the first floor in order to go through passport control. Foreign nationals must fill in migration cards before passport control procedures. Racks for filling in migration cards are located at the area before the passport control line.
To collect your baggage you should go down to the baggage claim area located on the ground floor. . The information about baggage from arriving flights is shown on a display panel overhead a belt conveyor. Over-sized baggage is delivered separately.
After collecting your luggage you must go through customs control. Before entering the terminal hall you must present your baggage for inspection on special equipment and then present baggage tag to an agent at the baggage claim area.
Voronezh International Airport offers the following services: VIP lounge, business lounges, taxi, car rental, a hotel. You can also order a special service meeting and delivering of passengers from an aircraft using a comfortable car or a private car. To get more information and make an order, please call the Service Centre: +7 (473) 210-78-00.


text:
FEBS J. 2012 Oct;279(20):3952-64. doi: 10.1111/j.1742-4658.2012.08755.x. Epub 2012 Sep 11.
Structural determination of the phosphorylation domain of the ryanodine receptor.
Sharma P1, Ishiyama N, Nair U, Li W, Dong A, Miyake T, Wilson A, Ryan T, MacLennan DH, Kislinger T, Ikura M, Dhe-Paganon S, Gramolini AO.
Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
The ryanodine receptor (RyR) is a large, homotetrameric sarcoplasmic reticulum membrane protein that is essential for Ca(2+) cycling in both skeletal and cardiac muscle. Genetic mutations in RyR1 are associated with severe conditions including malignant hyperthermia (MH) and central core disease. One phosphorylation site (Ser 2843) has been identified in a segment of RyR1 flanked by two RyR motifs, which are found exclusively in all RyR isoforms as closely associated tandem (or paired) motifs, and are named after the protein itself. These motifs also contain six known MH mutations. In this study, we designed, expressed and purified the tandem RyR motifs, and show that this domain contains a putative binding site for the Ca(2+)/calmodulin-dependent protein kinase β isoform. We present a 2.2 Å resolution crystal structure of the RyR domain revealing a two-fold, symmetric, extended four-helix bundle stabilized by a β sheet. Using mathematical modelling, we fit our crystal structure within a tetrameric electron microscopy (EM) structure of native RyR1, and propose that this domain is localized in the RyR clamp region, which is absent in its cousin protein inositol 1,4,5-trisphosphate receptor.
© 2012 The Authors Journal compilation © 2012 FEBS.
Features of RyR1 C3 construct crystal structure
(A) Ribbon diagram of rabbit RyR1 C3 (2734-2940) construct containing two repeating RyR domains. The two structural repeats are related by an approximate 2-fold symmetry. The structure is predominantly α-helical with each repeat consisting of two α-helices (α1-4, red), a β-sheets (β1-2, yellow) and intervening loop segments (green). The electron density for residues between 2831 and 2848 was limited and the structure was approximated from the limited data available in this region (blue) (B) Schematic of sequence showing exact regions of α1-4 (red), a β 1-2 (yellow), 310 helices (pink), beta bridge (gold) amino acids and turns (purple). Indicated is the phosphorylation site Ser2843 and green squares indicate 6 MH mutations. (C) Surface charge distribution shows that the structure contains an outer positive area (red) and an inner negative are (blue) and that a 17Å central cleft is formed by the four helices (D) Comparison of our C3 crystal structure of the putative ryanodine receptor from Bacteroides thetaiotaomicron VPI-5482. Here the RyR repeats are shown individually as two RyR domain individual repeats (RyR domain 1 in gold and RyR domain 2 in blue) to aid in comparison to the putative ryanodine receptor from Bacteroides thetaiotaomicron VPI-5482 which was crystallised as a monomer.
Structural Determination of the Phosphorylation Domain of the Ryanodine Receptor
FEBS J. ;279(20):3952-3964.
Mapping of C3 crystal structure into Cryo-EM map of RyR1
(A) Docking of the RyR domain into the cryo-EM map of RyR1 tetramer (EMDB-1607) (gray) in the open state. The best solution placed the RyR domain (blue) at Subregion 10 which is localized approximately 75 Å away from the N-terminal ABC region (purple) previously positioned in Subregions 1, 2a and 2b []. Previously determined locations of a GFP inserted after Y2801 of RyR2 and the monoclonal antibody specific for residues 2756-2803 of RyR1[]are indicated by green and orange circles, respectively. Numbers indicate domain numbers (B) Side view of the docked molecules. (C) Close-up view of the RyR domain docked in the Subregion 10 showing the missing loop (residues 2831-2848) indicated by dashed line and phosphorylation site shown in red faces the centre of the tetramer but is located next to a cleft (D) Docking of the RyR domain in the cryo-EM maps of RyR1 in the open (blue ribbon with gray envelope) and closed (red ribbon and pink envelope) states. In comparison to the open state, the RyR domain in the closed state is rotated ~180° about its pseudo-2-fold axis with the phosphorylation site pointing outward
Mapping of MH mutations into C3 crystal structure
Mapping of the six known MH mutations onto our crystal structure shows that Glu2764, Glu2880, Thr2787, Arg2939 and are surface exposed residues where as Leu2867 although somewhat exposed, fits into a cleft defined by residue side-chains Q2924, L2927, K2928 and Q2931 and stabilizes the conformational arrangement of the α-3 (2869-2897) and α-4 (2916-2933) helices. The Arg2840 which is three residues upstream of the phosphorylation site localises to the missing loop in our structure.
Localisation of conserved and divergent residues mapped onto a surface representation of the C3 crystal structure
(A) Residues divergent (grey) and conserved (magenta) between RyR1 and RyR2 (B) Rotation of image in (A) by −90°. (C) Residues divergent (grey) and conserved (magenta) between RyR1 and RyR3 (D) Rotation of image in (C) by −90°(E) Residues divergent (grey) and conserved (magenta) between RyR1 isoforms across seven species listed in (F) Rotation of image in (E) by −90°.
Comparison of RyR1 and the IP3 receptor
(A) Overlay of the cryo-EM maps of RyR1 (EMDB-1607) (gray) and IP3R1 (EMDB-5278) (yellow) (B) Scheme of the primary sequence alignment of RyR1 and IP3R1. These proteins share 20–30% sequence identity in three different conserved regions (light yellow). The RyR domain (blue box) is present within the regulatory region of RyR, but not present in IP3R.
CaMKII binding to RyR
(A) Schematic showing constructs used for mass spectrometry analysis (B) Coomassie gel of purified RyR1 constructs in pET28a-LIC vector shows enrichment of each construct at the correct molecular weight (C) Schematic showing CaMKIIβ V5/6His constructs cloned into the pEF-DEST51 and western blot of C1-C3 constructs incubated with CaMKIIβ V5/6His showing binding only with C3 construct (D) Schematic showing C3 mammalian construct containing an N-terminal Flag tag used for immunoprecipitation and western blot analysis of the confirmation of binding between C3 and CaMKIIβ. Cell lysates from HEK-293 cells transfected with C3-Flag tagged and CaMKII–V5/6His tagged were subjected to immunoprecipitation experiments using the anti-V5 antibody (CaMKIIβ) (E) Western blot analysis of the binding of CaMKIIβ to wild type C3 construct and the C3S2843A mutant. Cell lysates from HEK-293 cells transfected with C3-Flag tagged, C3S2843A-Flag tagged and CaMKIIβ–V5/6His tagged were subjected to immunoprecipitation experiments using the anti-Flag antibody (RyR) and showed a 20% reduction of binding to the mutant when compared to wild type.
Publication type, MeSH terms, Substances, Secondary source ID, Grant support
Amino Acid Motifs/genetics
Blotting, Western
Calcium-Calmodulin-Dependent Protein Kinase Type 2/chemistry
Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism
Cryoelectron Microscopy
HEK293 Cells
Protein Isoforms/chemistry
Protein Isoforms/genetics
Protein Isoforms/metabolism
Protein Structure, Secondary
Protein Structure, Tertiary*
Ryanodine Receptor Calcium Release Channel/chemistry*
Ryanodine Receptor Calcium Release Channel/genetics
Ryanodine Receptor Calcium Release Channel/metabolism*
Ryanodine Receptor Calcium Release Channel
PDB/3RQR
Wellcome Trust/United Kingdom
84267-1/Canadian Institutes of Health Research/Canada
MOP-3399/Canadian Institutes of Health Research/Canada
MOP-84267/Canadian Institutes of Health Research/Canada
PhosphoSitePlus® - comprehensive post-translational modification resource - PhosphoSitePlus


text:
President of the Republic of Portugal visits Aga Khan Academy Maputo
His Excellency President Marcelo Rebelo de Sousa visited the Aga Khan Academy in Maputo on 13 January, while in Mozambique for the inauguration of its new President. He was accompanied by Ms Teresa Ribeiro, Secretary of State of Foreign Affairs and Cooperation of the Portuguese Government, and Ms Maria Amélia de Paiva, Portugal's Ambassador to Mozambique.
Learning the discipline of time management with a passion for sports
At the age of eight, Yannik Rahman discovered his passion and drive for tennis. Inspired by tennis players like Serena Williams, Roger Federer, and Novak Djokovic, Yannik has learned to conquer his fears and challenges during play-offs, from encountering gusty winds of 40 mph or persevering during a tournament despite his fractured shoulder. "Honestly, the main key for success in tennis and in life is to work hard and to believe that you can do anything, even in the toughest moments," says Yannik.
Saving the Environment - Florida Jamatkhanas Go Green in 2019
Florida Jamatkhanas have turned to eliminate usage of plastic water containers and plastic bags. These are just two steps, in addition to other best practices, to "Going Green." The initiative was launched January 1st in three Florida Jamatkhanas, and will continue to be implemented in the remaining two centers.
A Run for the Florida State Senate
Few have the vision and courage to run for public office. It is a difficult path to traverse, but one that allows those with a commitment to voice their concerns and stand up for their values. Annisa Karim, from southwest Florida, did just that. She ran for the Florida State Senate in 2018.
Aga Khan University celebrates partnerships in Lisbon
At a special dinner hosted in Lisbon on 13 April 2019, the Aga Khan University (AKU) celebrated its partnership with Portuguese universities on research and development initiatives. The event was attended by Mawlana Hazar Imam and Princess Zahra.
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