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The aim of Amazing Global Women Achievers (AGWA) is putting the spotlight on women that are contributing to the social and economic development of the their country. They are role models and serve as examples of what is possible for a younger generation of women in their country and across the globe.
AGWA is part of GlobalWIIN – the not-for-profit organisation based in London, United Kingdom which places the spotlight on women that deserve acknowledgment for their achievements in their country and across the globe.
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AGWA Kingdom of Saudi Arabia in 2023
HONORARY PRESIDENT FOR SAUDI ARABIA IS APPOINTED BY GLOBALWIIN
Rasha Al Rabdi is the Honorary President of the newly set up AGWA Saudi Arabia and was appointed by the founding organisation GlobalWIIN. This is a voluntary position and plays the role of leading the setting up of AGWA SSaudi Arabia.
Rasha Al Rabdi has an impressive background in education and the knowledge transfer sector. Her vast experience extends to the capacity building of young women in Saudi Arabia.
CALL FOR NOMINATIONS OF WOMEN THAT MAKE THE KINGDOM OF SAUDI ARABIA GREAT!
Nominations for women who make the Kingdom of Saudi Arabia great are welcome! Please send us a page profile on their achievements!
AGWA selection committee would consider the following 4 points:
Their determination
Any evidence to support the nomination
Amazing Women from all regions of the Kingdom of Saudi Arabia are especially encouraged to be nominated
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Let me tell you a success story from the golf industry. Not a rags-to-riches thing, but a success story, nonetheless.
It began back in the golden age of golf, when Johnny Miller and Jack Nicklaus were battling with even older greats like Arnold Palmer and Sam Snead.
John S. Ford was a young, hippy prodigy who worked in the custom club department at MacGregor Golf. He made clubs for the top-name pros, and made a name for himself in the golf industry.
John Ford's still making hand-crafted golf clubs, but for the average, retired golfer out of a shop in Central Florida that he called The Golf Institute.
When I met Ford he was running an inefficient, old-school operation.
No different than most golf industry marketing and advertising. He relied entirely on word-of-mouth, and he spent at least 45 minutes pitching every person who walked through the door. His closing rate wasn't bad, but he also scared off a lot of people. It was not an efficient system.
He knew he needed a better method, so we went back to the drawing board. Together.
The first step was to discover the heart of his business. Show me your soul and I'll show you your brand. It's a proven process that appealed to Ford's analytical nature.
While Ford studied marketing I studied his business. I witnessed the miraculous work he does with lousy golfers. I went through his process myself. I felt it all… Skepticism, curiosity, hope, and finally, my own ah-ha moment.
Then I wrote the book on Ford's brand.
We narrowed his audience. We identified the key storytelling element, the archetypes involved, and a pyramid of marketing messages.
It was a crossroads, both for Ford's business and for his golfing customers. They could stay on the common path of frustration, or they could take a more direct route to lasting improvement.
Our insight proved that it's not about clubheads, shafts, or even Ford's engineering prowess. It's contentment after every round of golf. It's hope, preparation and payoff.
The name "Golf Institute" didn't jive with the core brand concept, so step two became a quest for a new business name.
That's where Ford and I disagreed.
"Golf at the Next Level" was not my first recommendation. Nor my second.
But it's very literal, which he liked. And the tag line, "Up you go," sealed the deal for him.
While our designer was working on the brand identity, I was showing Ford how he could transform his selling process from a time-sucking nightmare into a money making proposition.
That's how the "See Putt Sink" putting workshop was born.
Ford wanted to keep the classes simple, so we came up with the minimum viable product… For just $29 Ford would change your perspective on putting forever.
That's a value proposition that resonates.
We built a website that pushed prospects to the putting workshop and enabled them to sign-up and pay online.
Then we did direct mail and local newspaper advertising to push traffic to the website. Everything is integrated, with the same messaging and the same graphic style.
Anyone who contends that print advertising is dead should talk to John Ford. Every little ad that he runs in the local paper fills up weeks worth of workshops. The ROI is indisputable.
The biggest challenge with the advertising was the amount of information, and the process of elimination. Ford wants to say everything, in every ad. We prefer brevity.
He wants to explain. We want to entice.
Today, 93% of Ford's revenues come directly from the workshops. His sales pipeline stays as full as he wants it to be, and he doesn't have to spend time making individual sales pitches.
Not only that, his closing ratio has improved.
The people who attend his classes are more informed because they've been to his website. Their expectations are set, they ask better questions and they're more primed to buy.
So in a nutshell, Ford has an efficient new sales pipeline that's constantly full of well-qualified leads. They pay him to listen to his sales pitch, and he closes 80% of those who attend a class.
Wouldn't you like to have that business model?
It's easy, and it costs a lot less than you might think. In fact, the first meeting is free.
Smiles make sales. Disarm them with optimism, and build on a friendly platform of genuine passion.
Branding. We build new brands from the ground up, or we help you articulate your existing brand ethos and communicate it clearly through graphic design and the written word.
Advertising. We all grew up in the advertising agency world. We produce effective advertising in all forms. It's creative work based on solid, strategic thinking.
Marketing management. We help business owners navigate the complex landscape of modern tactical marketing by integrating all the pieces and providing exceptional client services.
We're here to help you succeed. Simple as that. Nothing gets us more fired up than seeing our clients achieve their dreams.
Successful brands have meaning beyond money. They're built on a solid belief system of authentic values that attract like-minded people.
We believe that creativity is the ultimate business weapon. Inspired, innovative thinking is behind every great brand, from Apple to Zappos. We also believe that it's hard to be creative when you're up to your neck in day-to-day operations. Most business owners need a spark from the outside.
We believe that strategy is a creative exercise. Strategy drives the execution that produces results. If you have a me-too strategy, no amount of creative trickeration is going to produce the outcome you're looking for. Creative strategy plus creative execution is a formidable combination that your competitors will hate.
We believe that process matters. This is a service business, so how we work is often just as important as what we produce. We don't take shortcuts. For us, it's Insight first, then Execution. Every time. It's a process designed specifically to produce maximum results with minimal headaches.
We believe that every company needs a seasoned marketing generalist. A generalist can help you navigate the entire marketing landscape and make sure you're maximizing every marketing tactic by effectively managing the necessary specialists.
We believe in the persuasive power of disruptive words. Fact: Well-crafted messages with incongruent words work better. Because the human brain automatically screens out the normal, mundane language of most business pitches. It's in one ear, and out the other. Creative messages, on the other hand, fire the synapses and trigger an emotional response. Here's an example of great messaging.
We believe that emotion trumps logic every time. Research it yourself… the latest brain science proves that people make emotional purchases, then use reason to justify the decision. No great brand has ever been built on reason alone. Not one. In branding, it's what they feel, not what they think.
We believe the marketing MIX is more important than ever. The marketing landscape is evolving quickly. Facebook, Twitter, LinkedIn, Pinterest and Snapchat provide exciting new ways to tell stories and make connections, but technology itself isn't the story. You still need a healthy mix of marketing tactics. Some high tech, some high touch. Some old school, some new school.
We believe in the glory of a good story. Every great business has an engaging story to tell. So tell it! Find creative new ways to spin that tale, and keep telling it over and over again.We can help you tell it in creative new ways… in ads, on your website, in presentations, tweets and Facebook posts.
We believe in skeptical optimism. As creative thinkers we're naturally skeptical, but not in a pessimistic way. We question the status quo in order to move your business upward. Tell us that something can't be done, that it's too hard, or too "out there" and we'll be positively skeptical about that.
We believe Design belongs in business school. Tom Peters calls it "the soul of new enterprise." It's Design that differentiates the world's most valuable brand – Apple. It's Design that made Tupperware a cultural phenomenon. Design evokes passion, emotion and attachment… all required elements of great brands.
We believe in the art of persuasion. Data is a big deal these days. But effective marketing communications still comes down to saying the right thing, and saying it well. A brilliantly crafted combination of words and images will always be more motivating than data. Here's a relevant case study.
John's been called an anomaly… A creative guy with a penchant for business. A poetic entrepreneur.
He can devise an insightful strategy in the morning, and craft award-winning ad copy over lunch. He has a left-brain, right-brain one-two punch that few marketing executives offer.
John cut his teeth writing direct response ads — where sales were the only litmus test of success. From there, he worked for several Portland-area advertising agencies on a vast array of print and radio campaigns.
John also did a stint in the video industry where he wrote scripts and helped produce long-format videos and direct-response TV for big, national brands.
Eventually, John moved to Bend, Oregon to raise his kids and strike that delicate balance between work and play.
His first Bend advertising agency was named AdWords, which worked out well when Google decided they really, really needed that URL.
So he rebranded the firm.
John shares his expertise regularly on the Brand Insight Blog, which he's been writing since 2007.
In this day and age, inspired design often takes a back seat to the bells and whistles of modern technology. Too bad.
We believe subtle, aesthetic considerations have a pronounced affect on your brand and your overall business. That's why Elissa's a key team member at BNBranding.
Elissa has the uncanny ability to absorb brand strategies and translate them into gorgeous, relevant design work.
Over the years, she's been the design talent behind many award-winning brands, like the playfully random eBay logo, for instance, and the brilliantly simple Malibu Country Club brand identity.
Elissa's talents extend far beyond logos, into print and web design as well. And she sweats every detail. From the psychological effects of a color change to the usability implications of a specific website font, she works with the precision and care of a true craftsman and artist.
Eventually Erik goes deep down into some technological rabbit hole, and we don't hear from him for a couple days. But he always emerges with a workable solution. Every time.
The results are stunning… Websites that look as good as they perform. Web-generated leads that actually lead to something. With Erik's help you get higher conversion rates and analytics that your CFO will love. It's better with Zetter. Berg.
"I love learning, and I dive into subjects head first, including marketing. It's kind of an obsession of mine. I've worked with some big-name marketing guys across the country, but John Furgurson is my go-to guy. I'm very analytical, and I always over-think things. John has a good process that he follows, and he always has good ideas. Some of the work he's done for me over the years is just brilliant." – John Ford, Golf at the Next Level.
"As an interior designer I really appreciate the art and craftsmanship of the work they do at BNBranding. Their design work is meticulous and very well thought out. John Furgurson is the consummate professional… always delivers what he says he's going to deliver. They did my website and some very nice printed sales materials. It's first rate. I would definitely recommend them." – Lisa Slayman, Slayman Cinema.
They also went above and beyond with their namestorming process to facilitate discovery of our brand name. My relatively small, early investment with BNBranding was immensely worthwhile. I was able to launch my startup on the right foot, with a strong foundation. I now smile at my early mistakes that won't become disasters down the road. John is a skilled strategist who is easy to work with. He really knows his stuff.
Yep, it's a Bend Oregon branding company. The fresh air, the beauty and the outdoor action in Bend is beneficial to our creativity and productivity. It's the juice that keeps the ideas coming. If you'd like to mix business with pleasure with a visit to Central Oregon give us a call. We can arrange a rejuvenating, brand-oriented business trip that you can write-off.
BNBranding chosen to help launch a new brand in the nutritional supplements industry.
Organic 3 Inc., makers of Gut Pro probiotics and owner of Corganic Ecommerce has hired BNBranding to help them reorganize their lines and launch a new brand. The new brand name is still under wraps, as the two companies finalize their brand platform and launch plans.
BNBranding chosen to help launch a new health benefits company in California.
Incentive Health of Bakersfield, California has hired BNBranding to help them stir things up in the health benefits arena. The Bend, Oregon branding firm is working on a brand strategy, go-to-market plan, website, sales materials and a tactical marketing plan for the new company.
BNBranding launches new website and ecommerce store for Coconut Secret.
We're proud to be working Leslie's Organics, makers of the Coconut Secret Brand of natural foods. Leslie and Randy chose us to launch an ecommerce website and provide tactical marketing assistance.
Successful Branding — Zero-in on the Main Thing for Brand Loyalty.
I love this saying: "The main thing is to keep the main thing the main thing." I think Steven Covey coined that one.
When you boil it all down, that's the essence of successful branding: Zero-in on one thing you can honestly, passionately, expertly hang your hat on, and stick with it.
Then when it comes to marketing communications, come up with one idea to convey the main thing, and just pound that home in every way, shape and form you can afford.
One idea, multiple executions. Do that long enough — and handle your operations well — and you'll achieve brand loyalty.
Unfortunately, most business owners and brand managers don't have that kind of focus. Once they get a taste of success in one little niche, the temptation is just too much… They take their eye off the main thing, and dive into a lesser thing, hoping it will become the next big thing.
It seldom works out that way. The single biggest barrier to success, especially for young brands, is lack of focus.
Al Ries and Jack Trout call it the most violated of their "22 Immutable Laws of Marketing." They rail against line extensions and point to IBM, Microsoft, Levis, Heinz and this classic case: Crest.
It used to be very clear… Crest fights cavities. That was the micro script for the brand. The Main Thing.
Crest was the "first mover" in the cavity prevention category and it was a strategy that worked brilliantly, cementing Crest as the #1 toothpaste for more than 30 years.
Now there are 41 different kinds of Crest toothpaste. Count 'em! Crest Complete Multi-Benefit Extra White, Crest + Scope, Crest Lasting Mint, Crest Pro-Health Clinical Gum Protection, Crest Invigorating Clean Mint, Crest glamorous white, Crest vivid white, Crest baking soda & peroxide, Crest gel, Crest liquid gel, Crest whitening, Crest gum protection, Crest fluoride anti-cavity and sensitivity relief and even Crest Night Toothpaste.
Give me a break. The Main Thing now for Crest is just the next new gimmick. And it's no longer the #1 brand.
More and more line extensions is not the key to successful branding. All that Crest clutter just dilutes the brand and confuses the consumer. We have no idea what Crest stands for anymore.
It's natural for successful business owners and marketers to lose focus and start adding stuff to their portfolios of goods and services. They don't want to miss any opportunities, and they argue that many successful companies have a wide range of products. Apple, for instance.
But every Apple product is designed around the one Main Thing: Delightful Simplicity. All the innovation, design and technological prowess of Apple comes together in those two words. That's the heart of the Apple brand.
Remember this spectacular product launch for the iPod? The product design was disruptively simple and elegant. Even the advertising was delightfully simple.
There were plenty of other MP3 players on the market, but the white cord let everyone know you were listening to something different. And the graphic execution of the ads was brilliant. Overall, it was tremendously successful branding.
But you're not running the world's most valuable company. And chances are, you don't have The Main Thing really nailed down like Apple does. When you do, things will become easier.
Ries and Trout say: "Focus is the art of carefully selecting your category and then working diligently to get your self categorized in people's minds." In other words, successful branding is a long-term process that involves more than just the marketing department.
A good way to start is by saying no. Because when it comes to successful branding, what you DON'T do is just as important that what you do do.
Say no to the new investor that thinks you should add a mobile app to your mix.
Say no to the marketing consultant who says you're missing a great opportunity.
Say no to the guy who thinks you should open another location.
Sometimes you even have to say no to your biggest customer. It's not easy, and it's often unpopular within the ranks, but that's what focus is… NOT trying to be all things to all people.
If you'd like some help zeroing in on your main thing, call us. Because focus is the fundamental element of successful branding. 541-815-0075. For more on developing a clear brand strategy, try this post.
In 2009 I called it "A feel-good brand in a bummed out world." It was the type of organization that genuinely touched people, and put smiles on little faces. For me, a few minutes at Working Wonders Children's Museum was a sure cure for a crummy day. It was also a great example of non-profit branding.
Once we saw encouraging results from the research, we wrote a mission-focused brand strategy and built a business plan around that. After our strategy was clear, and the business plan written, we came up with a great name, designed a nice logo and put an operational plan in place based on our cohesive brand platform.
At first, it was just a concept. A "museum without walls." Initially we raised enough money to build some traveling exhibits and we went to every event in town to introduce kids, and their parents, to our brand of educational play.
And it caught on! Before the days of Twitter, it went viral.
Our bootstrapping, "museum without walls" strategy achieve the immediate goal: Proof of concept.
Parents and kids loved it. In less than three years we raised $400,000 and arrived at that crucial, "go or no-go" point. We had a location and we had enough money to open the doors. Just barely.
The argument TO go: We figured it'd be easier to raise money once people could see a finished children's museum. We knew we could spend years traveling around, trying to raise more money. (Many Children's Museums spend a decade doing that.) Or we could get the doors open, and go from there.
The argument to NOT go: We'd be undercapitalized. Cash would be tight, and there was no endowment safety net. We were relying on the on-going generosity of a couple key donors and most of all, corporate sponsors.
We chose to go. Damn the torpedoes!
A team of volunteers scraped up donated materials, did the heavy lifting, and created a children's museum that was small, but delightful. We launched in less than one-third the time and for one-fifth the cost of most children's museums. It was a labor of love. A thing of beauty. A non-profit branding success and the biggest accomplishment of my marketing career.
Working Wonders ran successfully for four years. It broke my heart when it had to close because of the economic tidal wave that hit our town in 2009. Despite our best efforts and exceptional marketing, it was not sustainable.
Some people contend it was actually branded too well.
Many customers and community leaders thought we were part of a national chain of some sort. Never mind that our marketing was done with volunteer labor. (mine) Never mind that our advertising was mostly donated space. The general public simply couldn't conceive of a little, local non-profit doing things so professionally. They figured we had all the money we needed, from some, mysterious, out-of -town source.
But there was no endowment. By the time we identified the perception problem and started addressing it with overt messaging, it was too late.
Our lessons learned from Working Wonders tie-in directly to an online discussion that I've been following about non-profit branding for marketing for 501c3 organizations. It's an informative conversation between branding professionals that everyone can learn from. Profit or not.
1.What happens when the public image of a non-profit organization suffers because of commercial branding strategies?
One could argue that's what happened with Working Wonders. However, there's more to the story than that.
If not for commercial branding practices the children's museum never would have opened in the first place. That's how we were able to touch so many kids. In hindsight, the execution of our marketing was not the issue. We did a great job of reaching the parents of young kids. They came in — over and over again.
Unfortunately, in the non-profit world customer satisfaction and brand loyalty doesn't always translate to financial viability. For children's museums loyal, repeat customers aren't enough. They also need loyal, repeat donors who can provide an endowment.
That's what we missed… the big dollar benefactors. In a town of only 100,000 people those are hard to find, so we relied heavily on corporate sponsorships, and those dried up overnight when the economy tanked.
As the online discussion points out, nonprofits are often torn between two marketing objectives. But the biggest effort HAS to be directed at board recruitment and fund raising.We woulda, coulda, shoulda spent less time getting kids in the door, and more time on a grass roots effort to raise money and load the board of directors with wealthy supporters.
So if you're working with a small, local-level non-profit, by all means, do a professional job with your marketing. Non-profit branding is absolutely important! But first and foremost, make sure you're telling your story of need to the right people. Solidify the base of financial support first, then open your doors.
It's always a delicate balance to demonstrate that dire need without looking desperate. That's your challenge as a non-profit marketer. And keep in mind, if the organization does not appear grass-rootsy, potential donors might jump to unfortunate conclusions about your funding sources.
If you're in a for-profit venture, look closely at the passion and commitment of the people who help build non-profit organizations. At Working Wonders, we were all deeply passionate about the needs of our young kids. That cause is what fueled us.
What's your "cause?" Every great brand has one, beyond just making money. Is it written down somewhere? Is your operational plan aligned with that? Does anyone really care? These are some of the key strategic questions you need to ask yourself, before you worry about executing your go-to-market plan.
1	How to sell more stuff online.
Awwwww, the traditions of autumn… Halloween candy, the first snow in the mountains, and holiday shopping. You've heard of Black Friday… the mayhem-loving bargain hunter's favorite day of the year. And "Cyber Monday," the online equivalent. They're coming up quickly.
The Wall Street Journal predicts there will be ninety six million online shoppers. That's almost one-third of America's population Googling for bargains. And there are probably nine million shopping sites to choose from.
Every e-commerce site from Amazon to Aunt Matilda's Potato Mashers will get their fair share of the buying frenzy. But most e-commerce businesses could get a bigger piece of the pie, if only they'd do something — anything — to differentiate themselves from pack.
You can't just regurgitate the manufacturer's product spiel. You need to customize your pitch, improve your copy, and mix up the words a bit.
Besides a ridiculously low price, what do online shoppers want? Most are looking for information. If they're not quite ready to fill their shopping cart, they need facts, reviews, articles or some kind of credible content that helps them narrow their search.
Amazingly few e-commerce brands actually fit the bill when it comes to informative content and sharp, convincing copy.
Take ski shops, for instance. I'm in the market for new ski boots, and I can't even get enough information to research boots on line, much less purchase them. After hours of work I know a lot more about boot fitting, but I don't know which models are most likely to fit my feet. In fact, I've been to every online ski shop I could find, and only one – REI – provides anything more than just the manufacturer's stock product spiel.
If you want to establish a successful on-line brand you have to do more than just copy your competitors. You can't just cut and paste the same exact blurb, same photo and the same specs and expect more market share than anyone else. You have to differentiate your store. Somehow.
Or you can have better content presented in your own, unique voice. That, you can do!
Toenails blackened and torn. Crippling leg cramps. Wasted $90 lift tickets. Ruined vacations. Endless trips back to the ski shop.
Those are the honest-to-goodness repercussions of getting it wrong. That's the stuff of compelling sales copy. Not bullets from the manufacturer's spec sheet. But not a single online ski shop capitalizes on those emotional hooks. They're all just lined up, offering the same brands at the same prices with the same pitch.
That's not retailing. That's virtual warehousing.
Early in my career I wrote copy for the Norm Thompson catalog. Before J. Peterman ever became famous Norm Thompson had a unique voice that resonated with its mature, upscale audience. We wrote long, intelligent copy that told a story and filled in the blanks between technical specs and outstanding photography.
When the product called for a technical approach, we'd get technical… I remember writing a full page spread on the optics of Serengetti Driver sunglasses.
For other products we'd turn on the charm and use prose that harkened back to more romantic times.
These weren't just adjectives thrown in to boost our word count. They were themes on which we built compelling, product-driven stories. The narratives explained why the product felt so luxurious. Where the innovation came from. How a feature worked. And most importantly, what it all meant to the Norm Thompson customer.
It was the voice of the brand, and guess what? It worked. The conversion rates and sales-to-page ratios of the Norm Thompson catalog were among the highest in the industry.
Ski boots don't exactly fit into the category of top on-line sellers. They aren't impulse items that you need on a weekly basis. They're heavy to ship. And returns on ski boots must be astronomical.
Most boots don't even come close to fitting my feet, so no technical feature is as important as fit. And yet no website that I've found provides the simple problem-solving content that says: If you have a D width foot, try this make and model. If you have a high instep, try these. If you have a narrow foot, try these.
It's not rocket science. It's just simple salesmanship . The kind you'd get if you walk into any decent ski shop.
And I guess that's what I'd like to see more of on line. Better salesmanship. At least for the product categories that require more than just a quick glance at the price. Like ski boots.
And one other thing… If you choose to sell like everyone else, at least make your site convenient to use, and functional from a usability standpoint. I visited one online shop that didn't even have a working search function. I typed in "Soloman Ski Boots" and got dozens of Soloman products, but not one ski boot. I'll never go back. Online shoppers often know exactly what they want. Might as well make it easy for them to find it.
Here's a news flash for all of you who are 35 or under: Flying wasn't always this bad. There was a time when racking up frequent flyers miles was, actually, a little glamorous. You could fly the friendly skies and have a pleasant time. Sometimes the experience even lived up to the airline industry marketing hype.
Sure enough, a small airline out of Toronto is jumping in, and turning the clock back to better days in coach.
It's still too early to tell if Porter Airlines will become a long-term success story in the airline industry, but there's a lot to be learned from their launch. From a branding standpoint, they've done it right.
In 2006, Robert Deluce, Porter's CEO, made a conscious decision to build his airline around the brand, and vice-versa. According to Marketing News, he approached branding agencies with his vision, a business plan and a well-defined value proposition built on three things: speed, convenience and customer service.
Convenience was guaranteed by making Toronto's City Center Airport the home base, eliminating a long commute from Pearson International.
Early on, Winkreative, a branding firm with offices in London, New York and Tokyo, was hired to coordinate the entire affair. They handled everything from naming the company to the interior design of the airplanes, website development and furniture selection in the airline's lounge.
Rather than splitting it up between three or four firms, it was a well-coordinated effort based on a solid brand premise and a single creative approach. And it's carried through in every aspect of the operation.
I love the simplicity of the name. "Porter" conveys how the airline would carry passengers with care and help lighten their load. And the tagline, "flying refined," sums it up without pouring on the fluff.
Thankfully, the graphic design falls in line perfectly with the idea of refinement. If you say you're refined, you better look refined!
The sophisticated, subdued color palette and the quirky raccoon character work tremendously well together. Sorta reminds me of Olympic mascots from years past. You can debate the wisdom of using a raccoon, but the design work is fun, distinctive and superbly executed in every medium. No one's going to forget it once they've experienced it.
"This Canadian boutique airline is the most well-designed airline I'd ever been on and seemingly every detail had been given a lot of thought (including their adorable lunch boxes and chic on-board magazine named Re:Porter).
In terms of airline industry marketing, and a sophisticated brand design, Porter stands 30,000 feet above everyone else.
But the Porter brand is a lot more than just pretty pictures and a fancy in-flight magazine. From what I've heard and read, the entire operation is living up to its brand promise and exceeding expectations.
And after scouring the travel blogs, I couldn't find a single negative review.
Many people have never known anything but discomfort and inconvenience in air travel. So for them, Porter will be an entirely new experience, somewhat foreign and unexpected. And once they've flown Porter, their perception of the other brands will be forever tainted.
For older generations, Porter is a throw-back. An emotional trigger that harkens back to a simpler time when all the airlines did a better job.
I haven't flown Porter, but I hope to. (It's almost enough to justify a trip to my grandma's hometown in Nova Scotia.) I hope they can succeed in a tremendously difficult and competitive industry. I hope they can scale up their operation without sacrificing the heart of the Porter brand. And I hope more airlines follow suit.
But I'm not optimistic. Few airlines are built on such a solid brand premise, and most are just too darn big to change direction in any substantive way. So the opportunity for little carriers like Porter, will still be here for the taking.
If they can just remember those good 'ol days.
It's an old debate… can image advertising actually move the needle on bottom-line business objectives? Ad agency execs say yes, of course. But marketing directors, C-level execs and direct response guys are often skeptical.
My humble opinion… absolutely. When it's done well, "image" advertising certainly can achieve both objectives… move product AND cement the brand identity in popular culture.
There are many great examples of image advertising that has done exactly that… The Got Milk campaign. Absolute Vodka. Ipod intro advertising, to name a few.
Meet Gert Boyle, the iconic matriarch of Columbia Sportswear.
Gert inherited the family business in 1970 after her husband's untimely heart attack. At the time, Columbia was generating $650,000 a year in sales, but was teetering on the brink of insolvency. Although the company made a popular line of fishing and hunting apparel, profitability had been a problem for years.
To make matters worse, Neal Boyle had offered three family-owned homes and his life insurance policy as collateral for an SBA loan. The pressure was on.
After the first year Gert seriously considered selling. But when the deal fell apart she dug her heels in, made some tough decisions, and with help from her son Tim, turned the business around. By 1978 they reached $1 million in sales. By 1983, they were up to $12 million.
Ooops. It was a message more suited for the biggest competitors, like Patagonia or North Face, than Columbia.
Columbia's jackets weren't the most technical on the market, nor the most fashionable. It wasn't a brand you'd see on an expedition up Everest or in a popular skiing film, so the engineering angle missed the mark. It was image advertising that didn't capture the heart of the brand.
Columbia products represented functional practicality, not high-end technical features.
Their jackets sold for half the price of their competitors, and were perfectly suitable for 95% of the population who are outside enthusiasts, but not extremists. The brand was more about braving the Oregon rain than assaulting the seven summits.
So in the fall of 1984, Bill Borders, Wes Perrin and the team at Borders, Perrin & Norrander came up with something completely different.
They portrayed Gert as stubborn, finicky and overprotective. They showed the product and touted benefits, but always in context with a small, family-owned business and Mother Boyle's strict quality control standards. Nothing gets by her.
As it turned out, Gert embodied everything the Columbia brand is about. She was the most obnoxious, bullheaded, effective pitchman ever, and people loved her.
Once Gert and Tim realized they had a big hit they turned up the heat, outspending their competitors by a wide margin.
They started running TV spots where Gert used her hapless son as a product-testing guinea pig. She sent him through a car wash, dumped him unconscious on the summit of a mountain. Froze him in the ice and drove over him with a Zamboni. All with the tagline: Tested Tough.
Fun stuff. And spot-on from a branding standpoint.
"Our ads set us apart from the corporate pack. People related to us because they believe there is a person at Columbia who really cares. And the best thing about our ads is that they are true. I really do care." – Gert Boyle.
Authenticity. Differentiation. Credibility. And increased sales. What more could you want from image advertising?
When the campaign launched in 1984, sales were $18 million. By 1990 Columbia hit the $100 million dollar mark. Today they're the number one outerwear company in the world, doing $2.5 billion a year.
Unfortunately, Gert was absent from the brand advertising for ten years. While the company continued its growth, the advertising lost the edge that Borders had established. Columbia's website and on-line marketing efforts didn't have the brand personality of the old Gert Boyle ads, and began to look more like the predictable, stock imagery of all the other brands.
So in 2015, Columbia's advertising agency brought Gert back for the "Tested Tough" campaign, proving that her appeal stood the test of time.
For more on brand personality and image advertising, try this post.


text:
WATCHTHIS
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Home / Business / Technology
5G devices set to mature soon
By Ma Si | China Daily | Updated: 2018-03-22 07:40
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Visitors watch an intelligent mechanical device equipped with 5G technology in operation during an exhibition in Beijing.[Photo by Chen Xiaogen/for China Daily]
Nation playing important role in finalizing global standards
China is likely to issue 5G licenses to telecom carriers in the second half of next year at the earliest as the nation scrambles to commercialize next-generation mobile communication technology, Wang Zhiqin, an expert with the Ministry of Industry and Information Technology, told China Daily on Wednesday.
"5G devices will be mature for commercial applications in China in 2019. We will be among the first batch of countries to issue 5G licenses in the world, most likely between the second half of 2019 and the first half of 2020," said Wang, vice-president of the China Academy of Information and Communications Technology, a government think tank affiliated with the ministry.
Wang is also head of the IMT2020 (5G) Promotion Group, a team established under the ministry to accelerate the development of superfast technology in China.
In the past, China lagged behind other countries when issuing 4G and 3G licenses. But when it comes to 5G, the nation has already played an important role in finalizing the global standards and raced ahead in research and development.
"Frequency bands are likely to be distributed to telecom carriers in the second half of this year, which will accelerate the construction of 5G networks," Wang said.
According to her, medium-frequency bands will be used for 5G networks in the country and two of the country's three big telecom carriers, namely China Mobile and China Telecom, prefer to build standalone 5G networks from the very beginning, in contrast to the United States and South Korea where companies are building non-standalone 5G networks.
Non-standalone 5G deployment offers a way for companies to set up 5G stations by partially relying on current 4G network infrastructure while standalone architecture means building completely new ones.
"The cost of building a 5G base station will at least be 1.5 times that of a 4G base station, which will put pressure on telecom carriers," Wang said
"But the trend to innovate and apply 5G in a wide range of industries will motivate them to move fast," Wang said.
She made the remarks on the sidelines of a 5G application competition held in Beijing on Wednesday. The competition was aimed at encouraging companies from the automobile, electric power, medical and other sectors to communicate with telecom companies, in order to come up with innovative 5G application scenarios and solutions.
Liu Xuan, an employee from Shenzhen-based BGI, China's top gene-sequencing provider, said the company is engaged in a project using 5G technology to enhance medical services in remote areas.
"We are experimenting how to help doctors do sonograms for patients thousands of miles away by tapping into the superfast speed and extremely fast responses of 5G," Liu said.
China has already started its third-phase tests on 5G research and development, in the hope of getting pre-commercial system products ready by the end of this year.
China likely to issue 5G mobile licenses in 2019
ZTE invests over $3b on 5G products
Innovation runs from 5G wireless to wheels, wallets
China joins top ranks in field of 5G technology
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Shanghai's enterprise relief to give economy a jolt
City develops ice and snow tourism to boost local economy
Policies fuel impetus for China's high-quality development
Chinese people enjoy Spring Festival at home and abroad
People go shopping for the upcoming Spring Festival
China's tourism market picks up
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State Council News
Quick view: State Council executive meeting on Jan 28
China to boost economic rebound, stabilize foreign trade, investment
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Big gains overseas highlight laser equipment firms
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China's central SOEs report solid revenue, profit growth in Jan-Oct
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2023 Winter Davos
Growing in China, our business stories
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Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form.

redpajama_set_name: RedPajamaCommonCrawl


Featuring "Children Of Gaia", a track that has become anthemic in it's time in rotation on dubplate by the likes of Plastician and Kareful, the E.P. introduces a total of four tracks to it's audience. Sorsari's trademark lush and emotive chord sequences are prominent throughout, as are his cheeky references to rave music's past in the tail end switch ups on some of the tracks.
An absolute gem of a release that we're very excited to be a part of releasing, and something that is sure to be looked back on as one of the most important releases from the foundation of the Wave sound.


Sometimes you might don't have access to wireless internet at office or somewhere but you have cabled internet and you need to access internet from your mobile phone, then this solution will help you.
You can easily share the Wired internet into Wireless network mode by using this software.
This software act as a Virtual Wireless Router and use your laptop or pc wireless card to share the broadband internet wirelessly.
1. Download Virtual Router from here .
2. Install VirtualRouter on your Windows 7/Vista or XP.
3. Run the software from start menu.
4. In Network Name(SSID) field put a name for your WiFi network. ex "My_Hotspot"
5. In Password field , determine a password for your WiFi, it should be at least 8 characters.
6. Choose your wired internet source at Shared Connection section.
7. Click Start Virtual Router.
8. Now from your mobile,tablet or laptop search for wireless networks, you will find your network, in my case "My_Hotspot" then click connect. you will be asked for password, enter the chosen password in the virtual router.
1.Be sure the ip configuration for your mobile,tablet or laptop that want to connect internet via wifi set to DHCP and don't use manual IP configuration.
2.Be sure that your Antivirus/Firewall is not stopping the software from sharing the internet. MOST OF TIME THIS IS THE PROBLEM! So you need to declare a new rule for your firewall to let this software work freely or disable the firewall.
Try to disable the firewall or antivirus for a short while to see if its working or not? But your case sounds strange , how might viber & whatapps works but the browser don't!


text:
Packers 2018 roster prediction: Cornerback room gets 6 players
Baby Forum » INTERN » VORSTELLUNGEN » Packers 2018 roster prediction: Cornerback room gets 6 players
#1 | Packers 2018 roster prediction: Cornerback room gets 6 players 06.01.2020 04:45
liny195
Reggie White Jersey White , including 2 new faces Welcome to the prediction section of the offseason. Over two weeks, Acme Packing Company will present our overall roster predictions for the Green Bay Packers' season-opening 53-man roster. Today, we continue with the Packers' cornerbacks.Last season, the Packers defense allowed a passer rating of 102, which was 31st overall in the entire league. It was heartbreaking to watch. The only team who ranked worse was Cleveland Browns, and that was by a very slim margin (102.2). The Packers were also sixth-worst in 20+ yards passes allowed (55), third in completion percentage allowed (67.8%), and third in yards per completion allowed (7.9).Now, those terrible, horrible, no good, very bad defensive passing stats aren't solely the secondary's fault. A lack of a consistent pass rush and a poor defensive scheme didn't help. This is a new season with new potential for the Packers and their cornerbacks. Mike Pettine was brought in to coach up the defense, new rookie corners were drafted, and a familiar face was brought back to add a veteran presence. The APC staff made a prediction for six corners to make the final 53-man roster. We're expected to see a lot of nickel formations so keeping a healthy number of corners on the roster is essential. Starters: Kevin King, Tramon Williams, Jaire AlexanderBefore injuries sidelined Kevin King http://www.packerslockerroom.com/authentic-antonio-morrison-jersey , there were signs of him becoming a legitimate WR1 cover-man — most notably early last season when he matched up against Julio Jones and was trusted to defend A.J. Green. King is a 6'3," athletic corner who's not afraid to stick his nose in on run support. Despite being sidelined with a shoulder injury, hopefully he's still absorbed enough to make a second-year leap.The aforementioned familiar face coming back to Green Bay is Tramon Williams. At age 35, Williams is coming back to Green Bay as a veteran presence after spending the past three seasons split between Cleveland and Arizona. During his eight years with the Pack, Williams collected 28 interceptions and was a vital cog to the pass defense that helped produce a Super Bowl. Pettine is already gushing about how valuable Williams is to the cornerback room:Rookie Jaire Alexander will be the third starting corner according to the APC staff predictions. Taking a position in the slot will be a good role for the young corner considering his size (5'10," 196 lbs.) and his speed to keep up with shifty slot wide outs. While there were instances at Louisville where Alexander would get beat, a more disciplined approach will allow him to display his great ball skills more frequently. This will be a departure from last year's combo of Damarious Randall (717 snaps), Davon House (659 snaps) and Josh Hawkins (403 snaps) getting the lion's share of the cornerback snaps for the Packer D. Actually writing that out makes me feel like it can only get better.Reserves: Josh Jackson, Lenzy Pipkins, and Davon HouseJosh Jackson was the second rookie the Packers drafted following Alexander. In several mock drafts leading up to the draft, several had Jackson going in the first-round to the Packers at the 14th pick. Jackson has the size and nose for takeaways to develop into another boundary corner that could eventually take over for Williams. During his last season at Iowa, Jackson grabbed eight interceptions and displayed big play potential. Jackson didn't run well at the Combine, but apparently showed 4.4 speed at the Hawkeyes' Pro Day. It'll be exciting to see if Jackson can move into the starting lineup if he starts the season as a reserve. Full disclosure, Lenzy Pipkins is an APC favorite. An undrafted free agent, Pipkins only started one game in Week 17, but his willingness to tackle during his limited playing time was endearing to fans who were looking for some life out of the injury-ravaged secondary. Pipkins can play inside and out Geronimo Allison Jersey White , so that versatility should help his chances to make the final 53.Davon House is another corner who left northeast Wisconsin and eventually came back home. He spent 2015 and 2016 in Jacksonville before coming back to Green Bay last season on a one-year deal. The Packers decided to lock House back into another one-year deal this season prior to drafting two rookie corners. House was on the field for 12 games last season and managed to defend 6 passes during that time. Released: Herb Waters, Donatello Brown, Josh Hawkins, Demetri Goodson, Quentin RollinsRollins played 139 snaps last season and is the remaining corner from the 2015 draft that saw Randall and Rollins picked in back-to-back rounds by the Packers. Looks like the APC staff is projecting that that experiment is over. Waters has speed to develop into something and Hawkins put in a lot of snaps last season, but they're predicted to be on the outside looking in. Having two rookies at this position pushes a lot of players off the 53-man roster, but the cornerback position was in dire need of a revamp. Taking two swings at getting a starting-level corner from this past draft and a full Kevin King season is an upgrade from last year. It'll be exciting to see what an infusion of new blood can do to impact the whole defense. In a pivotal year for the Packers front office, these moves would help the Packers maximize improvement while preserving their long-term outlook."WhiteFanposts Fanshots Sections The APC PodcastPackers Film RoomFantasy Football Adviceoutlook.CSTShareTweetShareShareWhat does a perfect 2019 Packers offseason look like? Signing Adrian Amos won't have the sexiness of landing Earl Thomas, but for the money it's a better option for the Packers. Jeff Hanisch-USA TODAY SportsBrian Gutekunst has it all this offseason. A new coach, cap space, and a hoard of draft capital to put the Packers squarely back into playoff contention and competing for Super Bowls. With free agency days away and the draft rapidly approaching, we examine where the value might be in play addition, what it would cost, and how best to approach building this roster for 2019 and beyond. Aaron Rodgers' mega-deal doesn't hamstring the Packers as much as has been said and there are a couple moves Green Bay can make to free up even more money to spend if they so choose. The idea is to create a likely scenario, not just play Madden. With that in mind, here is one way to craft the offseason to maximize value and team improvement. Cut Nick Perry with a post-June 1 designation While this doesn't save the Packers in the short-term for free agency Montravius Adams Jersey , it frees up considerable cap in 2019 and 2020 which would help them sign their draft class and the Bashaud Breeland type free agents. More on Breeland to come. The money for his roster bonus wouldn't come off until June 2nd, but that alone is $4.8 million in relief. All in, the Packers would save $10.7 million with $4 million in dead cap for 2019 and $6.9 million in 2020 when the Packers will have gobs of cash to spend even without this move. Cut Tramon Williams This has more immediately salary cap relief implications for the Packers. The soon-to-be-36-year-old Williams has a cap hit of just under $6.4 million in 2019 but would save the Packers $4.7 million this offseason. That's enough to pay a legitimate starting-caliber player, like say a former starting cornerback forced to take the veteran minimum after a bizarre injury scuttled a free-agent contract.Re-sign Bashaud Breeland for three years, $18 million Before an infection in his foot voided the deal, Breeland signed a three-year, $24 million contract with the Panthers. Breeland joined the Packers on a minimum deal to rehabilitate his value and struggled with new injuries, a problem that hadn't cropped up in Washington. But given that rocky season and another year of age on his body, Breeland can't rightly demand the full $8 million APY he got in free agency a year ago.That said, he showed enough to be a starting-caliber player for the Packers, making splash plays when he was on the field. He'd be a stabilizing force in a secondary full of young players and wouldn't cost much. They're basically trading Breeland for Williams and an extra million dollars. That's a huge win for the Packers. Sign Anthony Barr for four years, $56 million The case for this contract is simple: top-of-market linebacker money even just for Anthony Barr the off-ball linebacker would be in the $10 million to $12 million range. He can't command a top 3-4 OLB contract because we haven't seen him full-time pass rush since UCLA. If his floor is a Pro Bowl jack-of-all-trades linebacker, this contract is only a slight overpay. The additional $2 million to $4 million is paying for that rush upside. More on why that makes sense here. Before the Perry cut, the Packers have roughly $34 million in cap space for this offseason. After the $14 million APY here (and they can play with the numbers as needed), they'd be down to $20 million. Sign Adrian Amos for four years, $32 million Four years is the window. That's how long the Packers have Aaron Rodgers under his mega-deal and that's the likely minimum number of seasons he'll be the starter barring major injury. Amos turns 26 next month Aaron Ripkowski Jersey White , which means he'll be 30 when this deal is over, putting it in the prime of his career. Overshadowed by rising star Eddie Jackson in Chicago, Amos brings the right skill set to play deep or in the box for the Packers in Mike Pettine's amoeba defense. The Bears may have to let him walk if they decide to pay Bryce Callahan and Amos isn't considered in the realm of top-of-market safeties like Landon Collins or Earl Thomas, even if he probably should be. Shave another $8 million off the cap space, leaving the Packers with $12 million left. Sign guard Quinton Spain for four years, $16 million Mark Glowinski re-signed with the Colts for $6 million APY, which sets the non-Rodger Saffold market. Spain played for Matt LaFleur last year in Tennessee, is just 28, and could come in to start at either guard spot for the Packers. He sits in that sweet spot of not overpaying for a name like Saffold but has clear value beyond the James Carpenter's of the free agent class. This would leave a little less than $7 million under the cap, with Perry's money set to come off the books in June. Plenty of money to sign the draft class and still have a rainy day fund. Draft Montez Sweat at No. 12 overallMaybe this is cheating a little after the combine where Sweat put together an all-time performance with athletic testing. If he's there, it's a no-brainer. If he's not, Clelin Ferrell provides more than enough value to justify his selection, as does Brian Burns, setting up the Packers to address their one remaining glaring need for a pure pass rusher. Signing Barr would also make it easier to let a player like Burns develop his body and technique without having to play 90 percent of snaps right away.Draft Chris Lindstrom at No. 30 overallLindstrom can play guard or tackle making him the kind of swing offensive lineman the Packers love. After testing as an elite athlete, with experience at tackle and guard, Lindstrom fits the profile for this front office to the letter. If Bryan Bulaga has to miss games Womens Jermaine Whitehead Jersey , Lindstrom slots in at right tackle, with the chance to be the successor. If Lane Taylor or Spain get hurt, Lindstrom can handle their role as well. Rush the quarterback and protect your own; no two tenants of the game are more important. Draft Irv Smith Jr. at No. 44 overallFrankly, the 20-year-old Alabama tight end would be a fine value at 30, despite measuring smaller at the combine than many anticipated. He still ran 4.6 and his agility testing belies the fluidity he shows in games. More importantly, he can block. Even if he's relegated to a glorified H-Back role, that has more value for the Packers than most teams because of Matt LaFleur's offense. Smith offers the perfect upside opportunity to take on a secondary role in 2019 as he grows into the NFL game, before taking over in 2020 once Jimmy Graham is out of the picture. Trade up to draft Juan Thornhill at No. 58 overallThere's a clear cut off around the top-50 of players capable of impacting games, not just in this class, but historically speaking. Someone will fall, they always do. Green Bay can package the 75th pick with both fourth-round selections to sneak back into the second to grab a player like Thornhill. He's the platonic ideal of a big nickel safety who can cover, play deep, and defend the run. Virginia even played him at cornerback in a pinch and though his outstanding athletic ability didn't consistently show up in college, the Packers should trust Mike Pettine to maximize him.
Name one facet of the Buffalo Bills offense and coach » « www.theseahawksfanshop.com


クリスマスが近づいてきます。イエス・キリストのご誕生を一緒に祝いましょう。Christmas is coming soon. Let's celebrate the birth of Jesus Christ together.
On 30th September, we had our harvest thanksgiving service. Many people brought fruits and vegetables to decorate the front of the church. Like last year, We donated them to the local children's home to show Christ's love to the community. On 28th October, we had the 'Light of the World' event. Pastor Makoto Fukui of the radio broadcast program gave a message on how to read the bible. We pray that this radio program will continue to be Christ's light to the community in Hanamaki.
今月のイベントを紹介します。Here are this month's special events.
On the 26th of this month, we had our church picnic. However, we had it in the church instead of the park because of the rain. Nevertheless, we had an enjoyable time. We sang songs, heard a bible story, and played games like 'Suika wari' (a game that involves people taking turns trying to split a watermelon while being blindfolded). It may have been dark and rainy outside, but the smiles of everyone inside brightened the day. At Megumi Café on the 30th, we had a Japanese tea instructor come give a Japanese tea ceremony, and we learned much about Japanese tea culture. It was a privilege, even if just a bit, to be able to experience 'Chado' (Japanese tea ceremony).


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Jaguar Radiator and heater core hoses.
This week's techbit is simple, but many people overlook it. If a radiator or heater hose blows, it's because heat, time and pressure have degraded its structural integrity to the point that the hose can no longer hold it in. What do many people do when a hose lets go? They replace that hose and fill their system, then drive off. WRONG!!! If one hose has degraded to the point of failure, then it's a pretty sure bet that the rest of them are following right behind. How many times do you want to overheat your aluminum engine? Take it from your ol' buddy: When one hose blows, replace them all. Same goes for belts.


Precision machining and assemblies for the most demanding industries: We also implement different processes, heat and surface treatments, all controlled by our production and quality management system with a real time production monitoring system.
We machine and assemble repetitive, small and medium series for electro-medical, aeronautics, shipbuilding, and the railway, energy, and defence sectors.
We count with an experienced finishing section to satisfy the needs of our customers.
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We offer the following types of heat treatments.
We deliver totally finished parts and assemblies ready for installation.
We also develop other specific processes, therefore offering global solutions to our customers.


text:
Home city guide geography of dombivli
Dombivli is a part of the Dombivli – Kalyan Municipal Corporation. Twin cities are just 7 kms away from each other. This is a suburban town of Mumbai situated on the east of Thane and is well connected to the city by local trains. The town of Dombivli lies at a distance of about 49 kms to the Northeast of the economic powerhouse of Mumbai. And around 17 kilometers from the last suburb in Thane district on the main central railway line. It is popular as a cultural hub and is counted amongst the most literate cities in India.
Geographical Location of Dombivli
Latitude: 19. 12'N
Longitude: 73. 6'E
Taluka: Dombivli
District: Thane
State: Maharashtras
Climatic Conditions in Dombivali
For tourists and leisure travelers, the best time to visit Dombivli are the months falling just after the monsoon and before summers. This is the time when this town has an array of festivities. Dombivli is blended with not only mild climate but also celebrations and joy brought by the festivals like Ganesh Chaturthi, Diwali. The town experiences high level of humidity with temperatures remaining moderate and it remains constant throughout the year.
The temperature in the month of October is recorded between 20 degree to 25 degree which drops down to 15 degree in the month of November and goes to a maximum of 20 degree only. Weather in Dombivli continues to remain mild in December and January where it fluctuates in between 12 degree to 17 degree. During spring season, in the months of February and March the temperature goes to a maximum of 27 degree. It rises slightly to a maximum of 30 degree in April when summers are still welcomed and goes to a maximum of 35 to 37 degree in the month of May when humidity is at its maximum from 88 to 92 per cent.
Summer Season in Domdivli
Summers in Dombivli last from the month of March to May with the maximum temperature reaching to 40 degree. Tourists do not prefer to visit the town during summers as the weather is really hot.
Monsoon Season in Dombivli
Monsoon season in the town starts from June and lasts till September. This season is accompanied by heavy rainfall with the level of humidity also increasing at the same time. This is also not a preferred season to visit Dombivli as the rainfall is heavy.
Winter Season in Dombivli
Winters in Dombivli start from the month of November and ends in February. Temperature during winters is quite low, dry and cool. It reaches to a minimum of 10 degree. Tourists and travelers are recommended to visit the town in this season as it is a perfect time to go out for sightseeing.
Demography of Dombivali
With a population of about 12,00,000 individuals which are spread across a distance of 15 square kilometers in Dombivli, the density of population of about 47000/ sq.km. in this town is overwhelming. In demographic terms, the urban conglomeration of Kalyan – Dombivli ranks to 21st in India with a population ranging to 1.20 million.
A major portion of this population consists of Maharashtrians speaking Marathi language. The cosmopolitan city consists of people from various parts of the countries and coming from different origins such as Gujratis, Tamilians, Jains, Punjabis, Kannadigas, Malyalees etc. With the new infrastructure facilities coming to the town, its looks will be changed in the coming years.
Comments / Discussion Board - Geography of Dombivli


text: cat webshot.pid | xargs kill -9

redpajama_set_name: RedPajamaGithub


text:
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{
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    {
        parent::__construct($env);

        $this->blocks = array(
            'stylesheets' => array($this, 'block_stylesheets'),
            'sidebar' => array($this, 'block_sidebar'),
        );
    }

    protected function doGetParent(array $context)
    {
        return "::base.html.twig";
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    public function isTraitable()
    {
        return false;
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text:
United States Attorney's Office[...]
Brunswick Corporation
Brunswick Appoints Dr. John Reid Vice President – Enterprise Technologies
Arrowhead Pharmaceuticals Inc.
Arrowhead Pharmaceuticals to Webcast Fiscal 2020 First Quarter Results
CHF Solutions Inc.
CHF Solutions Announces Launch of Aquapheresis Therapy Using Aquadex[...]
Ionis Pharmaceuticals Inc.
Akcea and Ionis Announce Initiation of NEURO-TTRansform Phase 3 Clinical Trial for AKCEA-TTR-LRx in Patients with Polyneuropathy Driven by Hereditary TTR Amyloidosis
BOSTON and CARLSBAD, Calif., Nov. 25, 2019 (GLOBE NEWSWIRE) -- Akcea Therapeutics, Inc. (NASDAQ: AKCA), a majority-owned affiliate of Ionis Pharmaceuticals, Inc., and Ionis Pharmaceuticals, Inc. (NASDAQ: IONS), today announced initiation of the NEURO-TTRansform Phase 3 clinical trial for AKCEA-TTR-LRx in patients with polyneuropathy caused by h856ereditary TTR amyloidosis, or hATTR amyloidosis.
'The initiation of the TTRransform Phase 3 program represents an expansion of our dedication and commitment to the ATTR community. The NEURO-TTRansform study is the first of two Phase 3 studies that we expect to initiate with AKCEA-TTR-LRx. Our Phase 1 data are encouraging and we are excited about the possibility of delivering a significant advancement for people living with hATTR amyloidosis,' said Damien McDevitt, Ph.D., interim chief executive officer at Akcea.
AKCEA-TTR-LRx is an antisense drug developed using Ionis' proprietary LIgand Conjugated Antisense (LICA) technology platform and is designed to inhibit production of TTR. It was discovered by Ionis and is being co-developed by Ionis and Akcea. In a Phase 1 clinical trial, patients treated with AKCEA-TTR-LRx experienced reductions in TTR of up to 94 percent.
'The Phase 1 data of AKCEA-TTR-LRx are consistent with the clinical profile seen across our other LICA programs, highlighting the potential of LICA-engineered therapies to address both rare and more common diseases,' said Brett P. Monia, Ph.D., chief operating officer of Ionis. 'We remain dedicated to advancing this important clinical development program as rapidly as possible and are hopeful about the prospect of bringing a new safe and effective treatment to people living with the devastating symptoms of hATTR amyloidosis in the years ahead.'
NEURO-TTRansform Phase 3 Study Design
NEURO-TTRansform is a global, open-label, randomized study evaluating the efficacy and safety of AKCEA-TTR-LRx in patients with polyneuropathy due to hATTR amyloidosis. The study will enroll 140 adult patients with stage 1 or stage 2 polyneuropathy and will be compared to the historical placebo arm from the TEGSEDI® (inotersen) NEURO-TTR Phase 3 study that was completed in 2017. Of the total 140 participants, 20 patients will begin on TEGSEDI and move to AKCEA-TTR-LRx after week 35. The primary endpoint analysis will be completed at week 66 and all patients will be followed until week 85 when they will have the option to transition into the open label extension study.
The co-primary efficacy endpoints at week 66 are:
Percent change from baseline in serum TTR concentration;
Change from baseline in the modified Neuropathy Impairment Score +7 (mNIS+7), a measure of neuropathic disease progression; and
Change from baseline in Norfolk Quality of Life Questionnaire-Diabetic Neuropathy (Norfolk QoL-DN).
There will be an interim analysis at week 35 where the co-primary efficacy endpoints are percent change from baseline in serum TTR concentration and change from baseline in mNIS+7.
For more information on the NEURO-TTRansform study, please visit www.clinicaltrials.gov.
ABOUT AKCEA-TTR-LRx
AKCEA-TTR-LRx is an antisense drug that uses Ionis' advanced LIgand Conjugated Antisense, or LICA, technology. It was discovered by Ionis and is being co-developed by Ionis and Akcea. AKCEA-TTR-LRx inhibits the production of the transthyretin (TTR) protein at its source. AKCEA-TTR-LRx is in development to treat a broad population of patients with both hereditary and wild-type forms of transthyretin amyloidosis, or ATTR amyloidosis.
ABOUT HEREDITARY TRANSTHYRETIN (hATTR) AMYLOIDOSIS
hATTR amyloidosis is a severe, progressive, and life-threatening disease caused by the abnormal formation of the TTR protein and aggregation of TTR amyloid deposits in various tissues and organs throughout the body, including in peripheral nerves, the heart and intestinal tract. The progressive accumulation of TTR amyloid deposits in these organs often leads to intractable peripheral sensorimotor neuropathy, autonomic neuropathy, and/or cardiomyopathy, as well as other disease manifestations. hATTR amyloidosis causes significant morbidity and progressive decline in quality of life, severely impacting activities of daily living. The disease often progresses rapidly and can lead to premature death. The median survival is 4.7 years following diagnosis. Additional information on hATTR amyloidosis, including a full list of organizations supporting the hATTR amyloidosis community worldwide, is available at www.hattrchangethecourse.com or by visiting www.hATTRGuide.com.
ABOUT IONIS PHARMACEUTICALS, INC.
As the leader in RNA-targeted drug discovery and development, Ionis has created an efficient, broadly applicable, drug discovery platform called antisense technology that can treat diseases where no other therapeutic approaches have proven effective. Our drug discovery platform has served as a springboard for actionable promise and realized hope for patients with unmet needs. We created the first and only approved treatment for children and adults with spinal muscular atrophy as well as the world's first RNA-targeted therapeutic approved for the treatment of polyneuropathy in adults with hereditary transthyretin amyloidosis. Our sights are set on all the patients we have yet to reach with a pipeline of more than 40 novel medicines designed to treat a broad range of diseases including cardiovascular diseases, neurological diseases, infectious diseases, pulmonary diseases and cancer.
To learn more about Ionis visit www.ionispharma.com and follow us on Twitter @ionispharma.
ABOUT AKCEA THERAPEUTICS
Akcea Therapeutics, Inc., a majority-owned affiliate of Ionis Pharmaceuticals, Inc. (NASDAQ: IONS), is a biopharmaceutical company focused on developing and commercializing drugs to treat patients with serious and rare diseases. Akcea is commercializing TEGSEDI® (inotersen) and WAYLIVRA® (volanesorsen), as well as advancing a mature pipeline of novel drugs, including AKCEA-APO(a)-LRx, AKCEA-ANGPTL3-LRx, AKCEA-APOCIII-LRx, and AKCEA-TTR-LRx, with the potential to treat multiple diseases. All six drugs were discovered by Ionis, a leader in antisense therapeutics, and are based on Ionis' proprietary antisense technology. TEGSEDI is approved in the U.S., E.U. and Canada. WAYLIVRA is approved in the E.U. and is currently in Phase 3 clinical development for the treatment of people with familial partial lipodystrophy, or FPL. Akcea is building the infrastructure to commercialize its drugs globally. Akcea is a global company headquartered in Boston, Massachusetts. Additional information about Akcea is available at www.akceatx.com and you can follow us on Twitter at @akceatx.
AKCEA AND IONIS FORWARD-LOOKING STATEMENT
This press release includes forward-looking statements regarding the business of Akcea Therapeutics, Inc. and Ionis Pharmaceuticals, Inc. and the therapeutic and commercial potential of AKCEA-TTR-LRx. Any statement describing Akcea's or Ionis' goals, expectations, financial or other projections, intentions or beliefs, including the commercial potential of AKCEA-TTR-LRx or other of Akcea's or Ionis' drugs in development is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to certain risks and uncertainties, particularly those inherent in the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. Akcea's and Ionis' forward-looking statements also involve assumptions that, if they never materialize or prove correct, could cause its results to differ materially from those expressed or implied by such forward-looking statements. Although Akcea's and Ionis' forward-looking statements reflect the good faith judgment of its management, these statements are based only on facts and factors currently known by Akcea and Ionis. As a result, you are cautioned not to rely on these forward-looking statements. These and other risks concerning Akcea's and Ionis' programs are described in additional detail in Akcea's and Ionis' quarterly reports on Form 10-Q and annual reports on Form 10-K, which are on file with the SEC. Copies of these and other documents are available from each company.
In this press release, unless the context requires otherwise, 'Ionis,' 'Akcea,' 'Company,' 'Companies,' 'we,' 'our,' and 'us' refers to Ionis Pharmaceuticals and/or Akcea Therapeutics.
Ionis Pharmaceuticals™ is a trademark of Ionis Pharmaceuticals, Inc. Akcea Therapeutics®, TEGSEDI® and WAYLIVRA® are trademarks of Akcea Therapeutics, Inc.
Akcea Investor Contact:
Kathleen Gallagher
Vice President of Communications and Investor Relations
Akcea Media Contact:
Lynn Granito
Berry & Company
Ionis Investor Contact:
D. Wade Walke, Ph.D.
Ionis Media Contact:
Roslyn Patterson
Vice President, Corporate Communications
Source: Akcea Therapeutics, Inc.
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text:
Instituto Agroalimentario de Aragón (IA2)
Instituto Agroalimentario de Aragón (IA2) Spain
The table to the right includes counts of all research outputs for Instituto Agroalimentario de Aragón (IA2) published between 1 November 2020 - 31 October 2021 which are tracked by the Nature Index.
Article Count and Share for Instituto Agroalimentario de Aragón (IA2)
Compare Instituto Agroalimentario de Aragón (IA2) with other institutions
Top 10 domestic collaborators with Instituto Agroalimentario de Aragón (IA2) by Share (7 total)
Instituto Agroalimentario de Aragón (IA2), Spain
Instituto Agroalimentario de Aragón (IA2) and Institute of Chemical Synthesis and Homogenous Catalysis (ISQCH) (0.74)
Instituto Agroalimentario de Aragón (IA2)0.13
Institute of Chemical Synthesis and Homogenous Catalysis (ISQCH)0.61
Instituto Agroalimentario de Aragón (IA2) and University of Zaragoza (Unizar) (0.63)
University of Zaragoza (Unizar)0.47
Instituto Agroalimentario de Aragón (IA2) and Spanish National Research Council (CSIC) (0.43)
Spanish National Research Council (CSIC)0.30
Instituto Agroalimentario de Aragón (IA2) and Instituto de Investigación Sanitaria Aragón (IIS Aragón) (0.26)
Instituto de Investigación Sanitaria Aragón (IIS Aragón)0.13
Instituto Agroalimentario de Aragón (IA2) and Institute of Health Carlos III (ISCIII) (0.26)
Institute of Health Carlos III (ISCIII)0.13
Instituto Agroalimentario de Aragón (IA2) and Agrifood Research and Technology Centre of Aragon (CITA) (0.24)
Agrifood Research and Technology Centre of Aragon (CITA)0.08
Instituto Agroalimentario de Aragón (IA2) and Aragon Institute of Health Sciences (IACS) (0.17)
Aragon Institute of Health Sciences (IACS)0.04
Top 10 international collaborators with Instituto Agroalimentario de Aragón (IA2) by Share (10 total)
Instituto Agroalimentario de Aragón (IA2) and UCL (0.52)
UCL0.48
Instituto Agroalimentario de Aragón (IA2) and European Molecular Biology Laboratory (EMBL) (0.16)
European Molecular Biology Laboratory (EMBL)0.13
Instituto Agroalimentario de Aragón (IA2) and Max Planck Society (0.15)
Instituto Agroalimentario de Aragón (IA2) and MRC London Institute of Medical Sciences (LMS) (0.11)
MRC London Institute of Medical Sciences (LMS)0.08
Instituto Agroalimentario de Aragón (IA2) and University of Cambridge (0.09)
University of Cambridge0.06
Instituto Agroalimentario de Aragón (IA2) and University of Minnesota (UMN) (0.09)
University of Minnesota (UMN)0.06
Instituto Agroalimentario de Aragón (IA2) and Imperial College London (ICL) (0.07)
Imperial College London (ICL)0.04
Instituto Agroalimentario de Aragón (IA2) and UK Research and Innovation (UKRI) (0.07)
UK Research and Innovation (UKRI)0.04
Instituto Agroalimentario de Aragón (IA2) and Harvard University (0.06)
Harvard University0.03
Instituto Agroalimentario de Aragón (IA2) and Harvard Stem Cell Institute (HSCI) (0.05)
Harvard Stem Cell Institute (HSCI)0.02
Bulked up batteries
University College Cork (UCC)
Dietary supplements protect adolescent brain from stress
No cool refuge for deep-sea life
The University of Queensland (UQ)


text:
Synthesis of SERS active nanoparticles for detection of biomolecules
Joanna Wrzesien, Duncan Graham
Pure And Applied Chemistry
Surface Enhanced Raman Scattering (SERS) can be used to detect specific DNA sequences by methods based on hybridisation of oligonucleotide functionalized nanoparticles to complementary DNA sequences. The problem, which has to be overcome to use this technique is that DNA is not strongly SERS active. This is due to the lack of a visible chromophore and presence of the highly negatively charged phosphate backbone, which prevents the electrostatic interaction with the metal surface necessary for the enhancement. To obtain SERS active DNA a label containing a surface seeking group, to allow adsorption of DNA on a metal surface, and a chromophore has to be attached to the DNA strand. Here we report the synthesis of three linkers containing a Raman tag [the following fluorophores were used for this purpose due to the fluorescence quenching ability of metallic nanoparticles: fluorescein, 6-aminofluorescein and tetramethylrhodamine (TAMRA)], surface complexing group (cyclic disulphide thioctic acid) and a chemical functionality for attachment of DNA (carboxyl group). Each of the linkers also contain poly(ethylene glycol) (PEG) (3 mer), which reduces non-specific adsorption of molecules to the surface of the nanoparticles and provides colloidal stability. The synthesized linkers were used to functionalize gold citrate (18 and 50 nm), silver citrate (40 nm) and silver EDTA (35 nm) nanoparticles. All of the conjugates exhibit high stability, gave good SERS responses at laser excitation frequencies of 514 and 633 nm and could be conjugated to amino-modified oligonucleotides in the presence of the commonly used (N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide hydrochloride-EDC center dot HCl with N-hydroxysulfosuccinimide or 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride-DMT MM, which has not been used for bioconjugate preparation previously. This approach is less time consuming and less expensive than previously used protocols and does not require the formation of a mixed layer of oligonucleotides and Raman reporter on the metal surface. Additionally the presence of a reactive functionality within the linker structure makes it possible to conjugate the linker to other biomolecules of interest such as proteins.
https://doi.org/10.1016/j.tet.2011.11.053
nanoparticle
10.1016/j.tet.2011.11.053
Dive into the research topics of 'Synthesis of SERS active nanoparticles for detection of biomolecules'. Together they form a unique fingerprint.
Raman Spectrum Analysis Medicine & Life Sciences 100%
4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride Medicine & Life Sciences 72%
Nanoparticles Medicine & Life Sciences 67%
Oligonucleotides Medicine & Life Sciences 47%
Nanoparticle Chemical Compounds 38%
Oligonucleotide Chemical Compounds 33%
Wolfson Merit Award: Responsive Nanoparticles for Multi-Modal Imaging
Graham, D.
Raman scattering 100%
Raman Spectrum Analysis 53%
Silver nanoparticles 40%
Nanoparticles 37%
The Molecular Nose
Graham, D. & Faulds, K.
EPSRC (Engineering and Physical Sciences Research Council)
Raman Spectrum Analysis 100%
Pterins 43%
Wrzesien, J., & Graham, D. (2012). Synthesis of SERS active nanoparticles for detection of biomolecules. Tetrahedron, 68(4), 1230-1240. https://doi.org/10.1016/j.tet.2011.11.053
Wrzesien, Joanna ; Graham, Duncan. / Synthesis of SERS active nanoparticles for detection of biomolecules. In: Tetrahedron. 2012 ; Vol. 68, No. 4. pp. 1230-1240.
@article{4ca753701a9a4f838a20dd4e8e78bb03,
title = "Synthesis of SERS active nanoparticles for detection of biomolecules",
abstract = "Surface Enhanced Raman Scattering (SERS) can be used to detect specific DNA sequences by methods based on hybridisation of oligonucleotide functionalized nanoparticles to complementary DNA sequences. The problem, which has to be overcome to use this technique is that DNA is not strongly SERS active. This is due to the lack of a visible chromophore and presence of the highly negatively charged phosphate backbone, which prevents the electrostatic interaction with the metal surface necessary for the enhancement. To obtain SERS active DNA a label containing a surface seeking group, to allow adsorption of DNA on a metal surface, and a chromophore has to be attached to the DNA strand. Here we report the synthesis of three linkers containing a Raman tag [the following fluorophores were used for this purpose due to the fluorescence quenching ability of metallic nanoparticles: fluorescein, 6-aminofluorescein and tetramethylrhodamine (TAMRA)], surface complexing group (cyclic disulphide thioctic acid) and a chemical functionality for attachment of DNA (carboxyl group). Each of the linkers also contain poly(ethylene glycol) (PEG) (3 mer), which reduces non-specific adsorption of molecules to the surface of the nanoparticles and provides colloidal stability. The synthesized linkers were used to functionalize gold citrate (18 and 50 nm), silver citrate (40 nm) and silver EDTA (35 nm) nanoparticles. All of the conjugates exhibit high stability, gave good SERS responses at laser excitation frequencies of 514 and 633 nm and could be conjugated to amino-modified oligonucleotides in the presence of the commonly used (N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide hydrochloride-EDC center dot HCl with N-hydroxysulfosuccinimide or 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride-DMT MM, which has not been used for bioconjugate preparation previously. This approach is less time consuming and less expensive than previously used protocols and does not require the formation of a mixed layer of oligonucleotides and Raman reporter on the metal surface. Additionally the presence of a reactive functionality within the linker structure makes it possible to conjugate the linker to other biomolecules of interest such as proteins.",
keywords = "SERS, nanoparticle, DNA, linker",
author = "Joanna Wrzesien and Duncan Graham",
doi = "10.1016/j.tet.2011.11.053",
journal = "Tetrahedron",
Wrzesien, J & Graham, D 2012, 'Synthesis of SERS active nanoparticles for detection of biomolecules', Tetrahedron, vol. 68, no. 4, pp. 1230-1240. https://doi.org/10.1016/j.tet.2011.11.053
Synthesis of SERS active nanoparticles for detection of biomolecules. / Wrzesien, Joanna; Graham, Duncan.
In: Tetrahedron, Vol. 68, No. 4, 28.01.2012, p. 1230-1240.
T1 - Synthesis of SERS active nanoparticles for detection of biomolecules
AU - Wrzesien, Joanna
AU - Graham, Duncan
N2 - Surface Enhanced Raman Scattering (SERS) can be used to detect specific DNA sequences by methods based on hybridisation of oligonucleotide functionalized nanoparticles to complementary DNA sequences. The problem, which has to be overcome to use this technique is that DNA is not strongly SERS active. This is due to the lack of a visible chromophore and presence of the highly negatively charged phosphate backbone, which prevents the electrostatic interaction with the metal surface necessary for the enhancement. To obtain SERS active DNA a label containing a surface seeking group, to allow adsorption of DNA on a metal surface, and a chromophore has to be attached to the DNA strand. Here we report the synthesis of three linkers containing a Raman tag [the following fluorophores were used for this purpose due to the fluorescence quenching ability of metallic nanoparticles: fluorescein, 6-aminofluorescein and tetramethylrhodamine (TAMRA)], surface complexing group (cyclic disulphide thioctic acid) and a chemical functionality for attachment of DNA (carboxyl group). Each of the linkers also contain poly(ethylene glycol) (PEG) (3 mer), which reduces non-specific adsorption of molecules to the surface of the nanoparticles and provides colloidal stability. The synthesized linkers were used to functionalize gold citrate (18 and 50 nm), silver citrate (40 nm) and silver EDTA (35 nm) nanoparticles. All of the conjugates exhibit high stability, gave good SERS responses at laser excitation frequencies of 514 and 633 nm and could be conjugated to amino-modified oligonucleotides in the presence of the commonly used (N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide hydrochloride-EDC center dot HCl with N-hydroxysulfosuccinimide or 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride-DMT MM, which has not been used for bioconjugate preparation previously. This approach is less time consuming and less expensive than previously used protocols and does not require the formation of a mixed layer of oligonucleotides and Raman reporter on the metal surface. Additionally the presence of a reactive functionality within the linker structure makes it possible to conjugate the linker to other biomolecules of interest such as proteins.
AB - Surface Enhanced Raman Scattering (SERS) can be used to detect specific DNA sequences by methods based on hybridisation of oligonucleotide functionalized nanoparticles to complementary DNA sequences. The problem, which has to be overcome to use this technique is that DNA is not strongly SERS active. This is due to the lack of a visible chromophore and presence of the highly negatively charged phosphate backbone, which prevents the electrostatic interaction with the metal surface necessary for the enhancement. To obtain SERS active DNA a label containing a surface seeking group, to allow adsorption of DNA on a metal surface, and a chromophore has to be attached to the DNA strand. Here we report the synthesis of three linkers containing a Raman tag [the following fluorophores were used for this purpose due to the fluorescence quenching ability of metallic nanoparticles: fluorescein, 6-aminofluorescein and tetramethylrhodamine (TAMRA)], surface complexing group (cyclic disulphide thioctic acid) and a chemical functionality for attachment of DNA (carboxyl group). Each of the linkers also contain poly(ethylene glycol) (PEG) (3 mer), which reduces non-specific adsorption of molecules to the surface of the nanoparticles and provides colloidal stability. The synthesized linkers were used to functionalize gold citrate (18 and 50 nm), silver citrate (40 nm) and silver EDTA (35 nm) nanoparticles. All of the conjugates exhibit high stability, gave good SERS responses at laser excitation frequencies of 514 and 633 nm and could be conjugated to amino-modified oligonucleotides in the presence of the commonly used (N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide hydrochloride-EDC center dot HCl with N-hydroxysulfosuccinimide or 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride-DMT MM, which has not been used for bioconjugate preparation previously. This approach is less time consuming and less expensive than previously used protocols and does not require the formation of a mixed layer of oligonucleotides and Raman reporter on the metal surface. Additionally the presence of a reactive functionality within the linker structure makes it possible to conjugate the linker to other biomolecules of interest such as proteins.
KW - SERS
KW - nanoparticle
KW - DNA
KW - linker
U2 - 10.1016/j.tet.2011.11.053
DO - 10.1016/j.tet.2011.11.053
JO - Tetrahedron
JF - Tetrahedron
Wrzesien J, Graham D. Synthesis of SERS active nanoparticles for detection of biomolecules. Tetrahedron. 2012 Jan 28;68(4):1230-1240. https://doi.org/10.1016/j.tet.2011.11.053


text:
Mapsidius auspicata is a moth of the family Scythrididae. It was first described by Lord Walsingham in 1907. It is endemic to the Hawaiian islands of Kauai, Oahu, Lanai and Hawaii.

The larvae feed on Charpentiera species. The larva live in a dense white silken tunnel on the leaves of their host.

References

External links

Scythrididae
Endemic moths of Hawaii

redpajama_set_name: RedPajamaWikipedia


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After the break you can find a brand new episode ofTravis Bickle on the Riviera, the world's only movie podcast. With your hosts Katie Skelly, Sarah Horrocks, and Sean Witzke.
Apples don't cost a nickel.
After the break you can find a brand new episode ofTravis Bickle on the Riviera, the world's only movie podcast. With your hosts Tucker Stone, Morgan Jeske, and Sean Witzke.
After the jump, Nate Patrin takes us all on a journey to the early 80s, when funk was going rock, rock was going pop, and new wave was going berserk. The era is widely used as a cheap punchline, but secretly proves to be a fertile time for technological innovation, genre crossover, and -- above all -- jams.


The idea of visiting a new country is always exciting and sometimes people might fall into the trap of not doing some groundwork before booking their flights. If you are among those people, you might find that you don't get a visa upon arrival, or that you should have sent your passport in advance in order to be stamped. This is quite a common occurrence, it is good to know that different countries do have different visa rules and that these differ from the country of origin of your passport.
For example, a person with an Italian passport can walk into Germany or any other EU country without the necessity of a travel visa, but, a person with an Indian passport has to apply for a Schengen travel visa, approximately one month or more in advance. Most of the official immigration websites currently list the documents and processing times required to apply for a visa. The tricky part is when you are in a foreign country and you want to add another country to your travel schedule. It might be important to find out if your country is included in the list of those able to apply for a visa from outside the country of origin itself. It would be great to have a website containing a comprehensive list of visa processing times, clarifying also if you actually need a visa or not, depending on the country of origin.