text:
Renflexis, a Remicade Biosimilar, Launched in US to Treat Crohn's and UC
by Jose Lopes, PhD
In Crohn's Disease, News.
New drug Renflexis (infliximab-abda), a therapy for ulcerative colitis and Crohn's disease, is being launched in the U.S., South Korea's Samsung Bioepis recently announced. Renflexis is a biosimilar of the anti-inflammatory drug Remicade (infliximab) and is being commercialized in the U.S. by Merck. Biosimilars are therapies with no clinically relevant differences to a biological reference product previously approved by the U.S. Food and Drug Administration (FDA). They present almost identical structure and activity to the reference product, and can be produced when the original product's patent expires. Renflexis was approved by the FDA in April 2017 as an injectable 100 mg dose to treat a number of autoimmune diseases (where the body's immune system attacks healthy cells), including ulcerative colitis and Crohn's disease. Renflexis may also be used by people with rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis. For Crohn's disease and ulcerative colitis, Renflexis is indicated to reduce signs and symptoms and achieve stable clinical remission in adult patients with moderate to severe disease who do not show successful response to conventional therapy. Renflexis taken for ulcerative colitis also aims to maintain mucosal healing (a measure of clinical activity) and eliminate corticosteroid use. Renflexis is also recommended for pediatric Crohn's disease in patients age 6 and older. Similar to Remicade, Renflexis consists of synthetically produced parts of antibodies. Both drugs block the naturally produced pro-inflammatory molecule tumor necrosis factor alpha (TNF-α), which is elevated in patients with some autoimmune diseases. "Since we were established five years ago, we have strived
Tagged Crohn's disease, Remicade, Samsung Bioepis, ulcerative colitis.
Previous: What It's Like Living with Someone with Crohn's Disease, Part 2
Next:Crohn's Disease Health: Mental Effects


text:
ALEX A. KONKIN
September 15, 1924 – April 24, 2015
Alex passed away peacefully at Hardy View Lodge in the presence of family members. He was born in Kelvington, Saskatchewan moving to Grand Forks at the age of 8. He enjoyed most of his adult life in the Boundary area contributing to the community through his ownership and operation of the Grand Forks Sash and Door. He was a gifted musician and played the accordion at many social gatherings. Alex is survived by his wife of 62 years, Marilyn, son Barry (Gladys), daughters Luba (Patrick Hall) and Terry (Wade Nearing) and five grandchildren. As well, survived by brothers Peter (Mary), Sarge (Fern) and Fred (Joanna). He is predeceased by parents Alex and Annie and brother Walter. The family would like to thank the staff at Hardy View Lodge and all the medical professionals for their care and kindness shown to dad. The funeral arrangements have been entrusted to the Baker Family of Grand Forks Funeral Home, gffh@shaw.ca

redpajama_set_name: RedPajamaCommonCrawl


text:
Translating Lay Summaries – Driving Transparency
Sep 18, 2020 | Machine Translation, Medical Translation, Medical Writing, Regulatory, Terminology
A study participant participates in a clinical trial, contributing invaluable data to understanding the safety and efficacy profile of a drug. Yet, patients, despite risking their lives by participating in a clinical trial, don't usually get to know the outcome of the clinical trial.
In the spirit of transparency, the EU Clinical Trials Regulation 536/ 2014 ((EU CTR Article 37) mandated that sponsors should submit a transparent, simplified summary of clinical trial results, the lay summaries (plain-language summaries (PLSs)) within a year of a trial being completed for studies in adults, and within six months of trial completion for studies in a pediatric population. The PLSs need to be provided in all EU languages for countries in which the study has been conducted and have to be submitted, along with the summary of the clinical trial results in the designated central EU portal and database (The Clinical Trials Information System (CTIS)).
The regulation came into effect on 16 June 2014 and is being rolled out in a phased manner. As the CTIS is expected to go live in December 2021, as was indicated by the European Medicines Agency (EMA) in June 2020, the submission of lay summaries on this portal for all new trials will then become mandatory. Some sponsors publish lay summaries on their own websites, as well as on portals such as TrialSummaries.com.
This rule is applicable to all interventional phase I to phase IV trials, involving at least one site in the EU regions. As per Article 27, it is also important that the informed consent form informs patients that the lay summaries will be made available in the designated central EU portal and also clarifies potentially when they would be made available.
The purpose of lay summaries is to explain the results of a clinical study in simple language, so that study participants and the general public can understand the study results. Lay summaries are strictly non-promotional, factual and objective documents that complement other forms of clinical study disclosure, but do not replace them. Ten elements need to be included in lay summaries as per Annex V of the EU CT Regulation, and this is the responsibility of the sponsor. They need to incorporate principles of health literacy, numeracy and cultural literacy, use simple, unambiguous language and an engaging tone. Health literacy is defined as the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions. As per the EU CTR regulation, readability needs to be targeted at a literacy proficiency level of 2–3 on the International Adult Literacy Survey scale, which implies that the lay summary should be easily understood by people 12 years of age and older. Yet, it is important that the language used does not talk down to the audience. One needs to understand for what patient population are lay summaries being developed, and use relevant, culturally sensitive language. The language and style used for populations of different ages and different cultures would need to be different.
While the EU requires the translation of the PLS into all European languages in the countries where the trial is being conducted, it is important to start with a well-structured Master PLS, presenting the overall study results and the primary endpoints of the study by treatment group. It is strongly recommended that inputs be sought from a panel, including patients, patient advocates, as well as healthcare professionals to ensure that the information is easily comprehensible to patients and strikes the right tone as well. Translating lay summaries requires the use of skilled linguists with clinical expertise so as to ensure that the scientific integrity of the results is not lost. The Translation Memory (TM) that is used should be configured to customer terminology to ensure consistency and accuracy. In addition to forward and backward translations, a comparative review by an independent linguist, and a clinical review by a subject matter expert, add value. Customer review may also be included as a part of the process.
The language assets that have been created should be updated in a repository, and libraries could be created per therapeutic area, to enhance both quality and efficiencies. While Machine Translation drive efficiencies, linguistic sensitivity and style result from the use of professional, skilled translators. It is said that a picture speaks a thousand words – visual imagery adds significant value and drives retention as well. The length of the document is also important – one wants to ensure that all relevant information has been shared, and all scientific jargon explained. That could run into many pages. Yet, how many patients would like to read a 10 to 20-page long document? Understanding the statistical relevance of trial outcomes can in itself be challenging to a scientific audience; trying to explain it to a lay audience is even more so. The challenge for scientific writers lies in simplifying detailed scientific content and communicating it in an engaging, yet non-promotional and a concise manner – that is no small ask!
The entire process should use experienced in-country, native linguists and companies should establish a PLS strategy, in alignment with their clinical development plan. PLS templates, style guides and glossaries need to be created and integrated with the TM.
The EU has clearly taken the lead in clinical trial transparency. In the US, the FDA does not mandate the submission of lay summaries, though it is strongly encouraged by the FDA. The Multi-Regional Clinical Trials (MRCT) Center at Harvard Return of Results Workgroup published two documents in 2015, the Return of Results Guidance and the Return of Results Toolkit. While the former is a practical guide to returning results and outlines the challenges involved, the latter, in addition to providing templates and toolkits, provides suggestions for translating endpoints into lay language, and shares some practical examples as well. The Center for Information and Study on Clinical Research Participation (CSICRP), in 2011, piloted programs with Pfizer and Eli Lilly wherein trial results were reproduced into lay summaries. Over 90% of volunteers were satisfied with their level of understanding, resulting in the FDA recommending that the CISCRP program should be adopted industry-wide. In January 2018, Scott Gottlieb, MD, announced a pilot to be run by the FDA, to improve public access to drug approval information. As the outcome of this pilot, the FDA published the posted portions of pivotal clinical study-related summaries of nine recently approved NDAs on Drugs@FDA.
The world is demanding transparency – as an industry it is our responsibility to share scientific knowledge in the simplest manner possible. It is our duty to patients and to the public to convey understandable information, drive transparency, and build trust.
About CSOFT Health Sciences
CSOFT Health Sciences provides end-to-end medical translations for all phases of the product lifecycle, from pre-clinical to post-launch. We also specialize in market access consulting, medical writing, and CTD/eCTD submissions with the FDA, EMA, and NMPA. Our operations are compliant with ISO 17100 and certified in ISO 9001:2015 and ISO 13485:2016, ensuring our customized solutions meet the rigorous regulatory requirements of global submissions.
About CSOFT
CSOFT International is a leading provider of cross-border communications for enterprises seeking growth in global markets. Our expertise in localization, documentation, and branding encompasses a full range of end-to-end content and consulting services that we deliver in over 250 languages. With a focus in health sciences and smart technology, we work closely with our clients to deliver precision solutions to the challenges of engaging markets, consumers, and regulatory environments worldwide.
More on: Machine Translation Medical Translation Medical Writing Regulatory Terminology


text:
Q: Formulário não cadastra, nenhum nome fica gravado Meu formulário não está salvando nenhum dado no banco, o que pode ser?

    <?php

      if(isset($_SERVER['REQUEST_METHOD']) AND $_SERVER['REQUEST_METHOD'] == 'POST'){

        extract($_POST);

    if(isset($nome))
        if($nome === '' OR strlen($nome)<4){
            echo 'Insira um nome existente';
        }elseif($sobrenome=='' OR strlen($sobrenome)<6){
            echo 'Insira um sobrenome existente';
        }elseif($email==''){
            echo 'Insira seu e-mail';
        }elseif(!preg_match("/^[az0-9_\.\-]+@[az0-9_\.\-}*{a-z0-9_\-]+\.[a-z]{2,4}$/i",$email)){
            echo 'E-mail invalido tente outro';
        }else{

            include('../../sllapsocial/classes/DB.class.php');

            $verificar = DB::getConn()->prepare("SELECT `id` FROM `usuarios` WHERE `email`=?");
            if($verificar->execute(array($email))){
                if($verificar->rowCount()>=1){
             echo 'Este e-mail ja existe';

         }elseif($senha=='' OR strlen($senha)<4){
            echo'Senha fraca Insira mais caracteres';
         }elseif(strtolower($capctha) <> strtolower($_SESSION['capcthaCadastro'])){
             echo 'Codigo errado';
         }else{
             $senhaInsert = sha1($senha);
             $nascimento = "$ano-$mes-$dia";
             $inserir = DB::getConn()->prepare("INSERT INTO `usuarios` SET `email`=?, `senha` =?, `nome`=? `sobrenome`=?, `sexo`=?, `nascimento`=?`cadastro`=NOW()");

             if($inserir->execute(array($nome,$sobrenome,$email,$senhaInsert,$nascimento,$sexo))){
            header('Location: ./');
               }

            }

           }

        }

        }

      ?>

Para ter acesso,É facil e gratis.

 <form name="cadastro" action="" method="post" >

Nome
         <input name="Nome" type="text" class="txtInput" value="<?php if(!empty($nome)) echo $nome; ?>" size="40"/>

             Sobrenome
             <input name="Sobrenome" type="text" class="txtInput" value="<?php if(!empty($sobrenome)) echo $sobrenome; ?>" size="40"/>

           Seu e-mail
             <input name="Seu e-mail" type="text" class="txtInput" value=" <?php  if(!empty($email)) echo $email; ?>" size="40"/>

             Insira o e-mail novamente
             <input name="Insira o e-mail novamente" type="text" class="txtInput" size="40" value=" <?php if(!empty($email)) echo $email; ?>" />

             Senha
             <input name="Senha" type="password" class="txtInput" size="40" value="<?php  if(!empty($senha)) echo $senha; ?>" />

           Data de nascimento
             <select name="Dia">
               <option value="">Dia</option>
               <?php
         for($d=1;$d<=31;$d++){
             $zero = ($d<10) ? 0 : '';
             if(!empty($dia)==$zero.$d){
             echo '<option selected="selected" value="',$zero,$d,'">',$zero,$d,'</option>';
             }else{
             echo '<option value="',$zero,$d,'">',$zero,$d,'</option>';
             }

         }

      ?>

             </select>

             <select name="Mes">
               <option value="">Mês</option>
               <?php
       $meses = array('','janeiro','fevereiro','março','abril','maio','junho','julho','agosto','setembro','outubro','novembro','dezembro');
       for($m=1;$m<=12;$m++){
       $zero = ($m<10) ? 0 : '';
       if($zero.$m == $meses){
        echo '<option selected="selected"value="',$zero,$m,'">',$meses[$m],'</option>';
       }else{
            echo '<option "value="',$zero,$m,'">',$meses[$m],'</option>';
       }
       }
      ?>

             </select>

             <select name="Ano">
               <option value="">Ano</option>
               <?php
      for($a=date('Y');$a>=(date('Y')-100);$a--){
          if(!empty($ano)){
              echo '<option selected"selected" value="',$a,'">',$a,'</option>';
          }else{
              echo '<option value="',$a,'">',$a,'</option>';
        }
      }
      ?>

             </select>

             Sou do sexo
             <select name="sexo">
               <option <?php if(!empty($sexo) == 'masculino') echo'selected"selected"'; ?> value="masculino" >Masculino</option>
               <option <?php if(!empty($sexo) == 'feminino') echo'selected"selected"'; ?>value="feminino" >Feminino</option>
             </select>

Digite o código acima:
             <input class="txtInput" type="text" name="captcha"  />
             <input type="submit" value="Continue" class="SubmitContinue" name="Continue" />
        </form>

A: 1 - Tome cuidado ao digitar nomes de campos/variáveis no html/php Nome é diferente de nome, veja no seu form como está definição:
<input name="Nome" type="text"

No php depois do extract() ele vai virar $Nome e não $nome.
if(isset($nome))

2- sql
Parecer ser erro de sintaxe no insert:
INSERT INTO `usuarios` SET
 `email`=?,
 `senha` =?,
 `nome`=? <---- falta uma virgula
 `sobrenome`=?,
 `sexo`=?,
 `nascimento`=? <---- aqui também
 `cadastro`=NOW()

Sempre que o mysql retornar o código 1064 sempre é algum erro de sintaxe como nome de coluna/tabela escrito errado ou aspas em lugares errados.
A mesnagem de erro é parecida como:

Error Code: 1064. You have an error in your SQL syntax; check the manual that corresponds to your MySQL server version for the right syntax to use near '' at line 1

Lista dos códigos  de erro mysql
Sintaxe ao alternativa do insert

redpajama_set_name: RedPajamaStackExchange


text:
Our Annual Reports
Corruption Researches
Global Corruption Barometer
National Integrity System
Corruption Risks and Management Practice in State-Founded LEPLs and N(N)LPs
The study of Legal Persons of Public Law (LEPLs) and Non-Entrepreneurial (Non-Commercial) Legal Persons (N(N)LPs) subordinated to the central and local government bodies has shown that the number of LEPLs and N(N)LPs as well as the number and remuner
Demirel College and the Chabuk case
The unfolding of events around the Demirel College teacher Mustafa Emre Chabuk have raised a lot of questions in the public about the impartiality of the state. There is strong public opinion that the Government of Georgia was coerced into its action
Tbilisi City Hall Pre-electoral Advertisement
In the course of the past couple of days, two TV stations, Rustavi 2 and Imedi, have been airing a video with the slogan "Done for Tbilisi". The narrator in the video talks about the infrastructural projects carried out in the years 2014-
Information on Investigation of High-profile Cases Remains Closed
Prior to the 2012 elections, coalition Georgian Dream promised to restore justice, restrain law enforcement from committing crimes, end illegal surveillance and free the media from political pressure. Despite these promises, a number of high-profile
Misuse of Administrative Resources during Electoral Processes Frequently Asked Questions
Q: What type of administrative resources can be misused during electoral processes?Judicial (Legislative, regulatory) InstitutionalFinancialEnforcemeQ: What is a judicial administrative resource and how it can be used for election purposes?A: In
Release of Lasha Tordia's video may involve an illegal action by the Interior Ministry
It was reported on September 7, 2017, that the Personal Data Protection Inspector established administrative liability of P.A.M. Club in connection to the case of Lasha Tordia, former General Auditor. Following investigation, the Inspector found that
Detained Former High-Ranking Tbilisi City Hall Official's Conflict of Interest
According to the information disseminated by the media on 31 August 2017, the Chief Prosecutor's Office detained former Deputy Head of the Tbilisi City Hall Architecture Service, Levan Dzagnidze, on the charge of attempted misappropriatio
Removing Representatives of Municipal Chairs from Staff Lists Violates Law
In June-July 2017, in the municipalities of Samegrelo-Zemo Svaneti, representatives of municipal chairs (so-called village representative/gamgebeli) were removed from the municipal staff lists. Service contracts were entered into with the individuals
NGOs Call Government to Wait for Venice Commission Opinion
On 1 September, the Venice Commission President Gianni Buquicchio stated that the postponement of the introduction of the proportional system in the Georgian Parliamentary elections to 2024 is disappointing. Additionally, Mr. Buquicchio negativ
Statement on the Selection of Candidates for the European Court of Human Rights
On August 29, the Government selected two new candidates for the European Court of Human Rights to substitute for the candidates rejected by the Council of Europe. The Coalition believes that the composition and rules that govern the work
The Right to Assembly and Manifestations: The Differing Positions of the Constitutional Court and the Parliamentary Majority
TI Georgia poll results: Two out of three adults receive spam SMS
Zugdidi Mayoral and district governor candidates' background and property ownership
Challenges of new immigration policies of Georgia
Who Owns Georgia: Meet David Iakobashvili, now in control of assets formerly owned by Dato Kezerashvili
61 Agmashenebeli Ave., 0102
Tel:+995 322 92 14 03
Kutaisi, Georgia
6 T.Tabidze Str. II Turn, 4600
Tel: +995 0431 25 45 31
74 Parnavaz Mepe Str., 6010
Tel:+995 0422 29 44 88
Zugdidi, Georgia
67 Konstantine Gamsakhurdia Str., 2100
Akhaltikhe, Georgia, Nebieridze Str.18, 0800, info@transparency.ge
© 2019 Transparency International Georgia
Website by Omedia


text:
Q: Nested Macro not expanding correctly I am trying to nest macro calls to ease converting between rust and c ffi types.
The inner macro generates calls to conversion functions from type names like this:
macro_rules! type_conversion {
    ($arg_name:ident, bool, BOOL) => (crate::type_wrappers::type_conversion::convert_rust_bool($arg_name));
    ($arg_name:ident, BOOL, bool) => (crate::type_wrappers::type_conversion::convert_c_bool($arg_name));
}

The outer macro now uses this to generate further conversions.
It basically works like this:
macro_rules! outer {
    ($arg_name:ident, $type1:ty, $type2:ty) => (type_conversion!($arg_name, $type1, $type2));
}

Now, when i try to use the outer macro like this:
fn outer() {
    outer!(hello_world, bool, BOOL);
}

I get this Error:
error: no rules expected the token `bool`
   --> src\type_wrappers\type_conversion.rs:252:77
    |
202 | macro_rules! type_conversion {
    | ---------------------------- when calling this macro
...
252 |     ($arg_name:ident, $type1:ty, $type2:ty) => (type_conversion!($arg_name, $type1, $type2));
    |                                                                             ^^^^^^ no rules expected this token in macro call
...
256 |     outer!(hello_world, bool, BOOL);
    |     ------------------------------- in this macro invocation

I cannot make sense out of this error, especially since CLions Macro expansion tool expands this into:
type_conversion!(hello_world , bool , BOOL )

Which is what i would expect and also, what the Error suggests.
Where is the Error in those Macros?

A: I guess the ty macro type cannot be casted to identifier (which bool & BOOL parameter are) and thus matched. So with ident type it works (playground):
macro_rules! outer {
    ($arg_name:ident, $type1:ident, $type2:ident) => {
        type_conversion!($arg_name, $type1, $type2)
    };
}


text:
The Gravelproof Hoof
- not just a dream
Adding a small amount of sodium bicarbonate to a horse's drinking water and/or feed has produced dramatic changes in some horses. After years of moving with a short stride and consequent toe-strike, the warmblood horse, Hopper, began moving with a long stride and heel-strike after only three days of sodium bicarbonate supplementation, commencing in March 2010, and has been able to maintain that normal, free movement. Another surprising result was that Hopper stopped cribbing and windsucking, a stereotypy that had been present for years. Go to the HOPPER main page to read his lifestory in full.
The mechanism by which sodium bicarbonate achieved that improvement is unknown. However, some clues may be found when considering the level of acidity or alkalinity in the horse's drinking water. The issue of body pH balance is highly complex and appears to be not fully understood even by experts working in that area. There is, however, agreement that extremes of both acidity and alkalinity are harmful.
An indepth tutorial of acid/base physiology can be found at:
http://www.anaesthesiamcq.com/AcidBaseBook/ABindex.php
Equine blood has very delicate pH parameters with baseline pH ranging from 7.42 to 7.45; the more this level drops towards 7.42 the more acid the blood has become. Some professionals consider lowered alkali reserves as the main cause of poor performance in equine athletes.
To ensure that the acidic components of stomach contents do not pass into the bloodstream, any food or fluids that are consumed by the horse must be neutralized by the body's own buffer systems which secrete bicarbonate, or be eliminated through feces and urine. Like all living creatures, individual horses may vary in their ability to neutralize acids. Factors that can adversely affect body alkali reserves include feeding excess proteins and starches, and the body's own bicarbonate levels becoming depleted.? Nervous, anxious horses are more prone to experience lowered alkali reserves due to the effect of stress on the digestive process.
Most town water supplies are adjusted so that pH is close to neutral (pH 7.0). Water pumped from underground reservoirs often contain alkaline minerals from the rock substrate in which they have formed. Similarly, running rivers and streams contain minerals from the ground over which they flow; water that naturally collects in ponds and lakes is also likely to contain minerals from soils and vegetation which results in freshwater lakes commonly being slightly basic.
See this reference for example:
http://ei.cornell.edu/watersheds/Acid_Rain_Experiments.pdf
Prior to domestication, equines would have had to drink water from wherever it could be found; pools or lakes formed by rainwater that had first travelled over hillsides and vegetation, or running streams. It is likely that most sources of drinking water would have been close to neutral or slightly alkaline. It appears that some horses may not be able to efficiently neutralize the carbonic acid in rainwater on a longterm basis, perhaps because there would have been little need to develop that ability if, throughout their environmental history, they were drinking water that was predominantly slightly alkaline from running streams, ponds or lakes. Most horses appear to prefer drinking water that is not acidic.
Urine pH is one way that may assist with assessing the body's ability to process ingested acids. The three horses on the chart below all ate the same diet, drank the same pH 6.0 rainwater, and had the same living conditions, yet there was a significant difference in their urine pH. Urine pH in the range between 7.5 to 8.5 is considered to be normal for horses (Manual of equine practice, R. J. Rose, D. R. Hodgson P. 404).
When sodium bicarbonate was added to their communal drinking water, the resulting difference in urine pH was quite surprising. Changes in urine pH occurred slowly over a two-week period.
Gante, with a urine pH of 6.0, had excellent feet but suffered from a persistent fungal skin infection, and an anxious temperament.
Rory, with a urine pH of 6.0 had Cushings and longterm hoof problems which are documented on the RORY main page.
Sol, with a urine pH of 8.5 had no obvious health issues with good, strong feet, no skin problems and no behavioural problems.
Gante's urine pH slowly increased to 7.0 while drinking rainwater with added sodium bicarbonate, and then increased again to 7.5 a couple of weeks after adding 30g of sodium bicarb to his feed. His fungal skin infection cleared immediately and has not returned although he remains mildly allergic to midge bites.
Rory's urine pH slowly increased to 8.5 with no positive or negative changes to his already-resolved hoof issues.
Sol's urine pH did not change, remaining at 8.5, and he continued to be problem-free
More research is needed on this subject, but it appears some horses who are drinking acidic rainwater may benefit from the addition of a small amount of sodium bicarbonate to raise the water pH to around neutral.
Horses drinking water that is already alkaline may not benefit from the addition of sodium bicarbonate, and it may even be harmful as excess alkalinity has been associated with enterolith formation.
An interesting overview of some of the benefits of sodium bicarbonate can be found at this link:
Bicarbonate has beneficial effects on health (News vol 3, no 1, May 2001)
http://www.mgwater.com/bicarb.shtml#library
Drinking water pH and urine pH can easily be tested with a pH meter, or with litmus paper dipsticks. A wide variation of readings is possible, depending on the brand of paper used.
For the sake of consistency, the paper sticks bearing two areas of reagent are recommended.
For accuracy, unit graduations of 0.25 are also preferable.
The 'pHion' brand has been reliable and is readily available online
WHERE TO BUY SODIUM BICARBONATE
Go to the SUPPLIERS page for more information on where to buy sodium bicarbonate in your country,
Any queries that arise after reading everything on this site can be directed to:
Gravelproofhoof@icloud.com
RORY INJURY
RORY HOOF PHOTOS
RORY RADIOGRAPHS
HOPPER HOOF PHOTOS
HOPPER RADIOGRAPHS
FEEDS - QUICK LOOK
BICARB
GASTRIC ULCERS
OXALATES
LOW PLANTAR ANGLE
All information on this site is intended for educational purposes only and should not be taken as nutritional advice for any horse. Notwithstanding that the author has made every attempt to ensure the information is accurate and based on fact, it is not intended to be used as a diagnostic tool and you should seek your own veterinary or other professional advice for any health or other concerns. The purpose of this website is merely to facilitate the sharing of knowledge and information based on the author's research. The author is not and will not be liable for any harm, loss or damage of whatsoever nature and howsoever caused and the author does not warrant the information is suitable for your individual needs. Use of the information published on this website is at your own risk.


text:
Q: how create a flag with EaselJS i find a simple canvas flag, but I have the question of how can I make it with EaselJS?
because in EaselJS documentation don't says about, make another canvas "without DOM interaction", and change pixel positions, but in EaselJS documentation I can't find how make it, and I have some questions:
1 Can i merge EaselJS code with normal Canvas code? Explanation, If I draw an animated North Korean flag star with some textures, can I make the static draw with EaselJS, and animate it with naked canvas code?
2 is possible make it with other library?, such as LimeJS or other libraries
3 I must use a WEBGL Library?, such as Three.js?


text:
Q: How to access foreignkey/ OneToOneField table's data from a ModelForm? I have a model called Profile that is related to the User Model. I would like to make a ModelForm for the model Profile. I would like that form to be able to access user's fields.
class Profile(models.Model):

user=models.OneToOneField(settings.AUTH_USER_MODEL,related_name='profile',on_delete=models.CASCADE)

address = models.CharField(max_length=250)

contact_number = models.IntegerField(max_length=20)

def __str__(self):

return self.user.first_name

class ProfileForm(forms.ModelForm):

class Meta:

model=Profile

fields=['first_name','address','contact_number']

The error shown is
django.core.exceptions.FieldError: Unknown field(s) (first_name) specified for Profile

Thank you.


text:
Shop AMR Shop AMR Pro
Standing the test of time as one of motorsport's most stylish partnerships, Hackett London and Aston Martin Racing is a thing of true class.
As the team's longest continual sponsor, having started the collaboration in 2005, Hackett are the official clothing partner to the team with a rich history of racing inspired garments in the archive.
"A casual conversation in our Sloane Street store with a director from Aston Martin 10 years ago resulted in a collaboration with Aston Martin that exists to this day. At the time I remember thinking, who wouldn't want to be associated with the most famous British brand in the world?"
- Jeremy Hackett
Aston Martin Racing Pro
Discover Aston Martin Racing Pro, the brand new collection that puts a technical spin on athleisure classics.


text:
Sightseeing Tours from Split, Croatia
From Split or Trogir you can visit three of Croatia's stunning national parks, each with its own unique character.
Komati has more than 140 islands and islets, Kika has waterfalls galore and a network of forest pathways, Plitvice has 16 natural lakes connected by waterfalls that cascade over natural travertine dams. There will be time for a swim on all these tours.
Full day sightseeing tours of Split and Dubrovnik are available, or you can do a one hour walking tour of the historic centres of Split or Trogir.
Visit the neighbouring Republic of Bosnia and Herzegovina. See two contrasting towns - the Ottoman influenced Mostar, named after its beautiful 16th century Old Bridge Stari Most, and visit the mosque and colourful bazaar, and Medjugorje, which became a place of pilgrimage for Catholics in 1981, after a group of local teenagers reported having visions of the Virgin Mary on "Apparition Hill"
Dubrovnik Full Day Tour
Plitvice Lakes & National Park Tour - From Split


lilacvault08 100 days ago News protectstar All https://www.protectstar.com Discuss Published New Discard Success!
Deactivate the camera of your Mac with the Mac Webcam Blocker App: How to stop people from accessing your MacBook webcam? Camera Guard™ Mac makes sure that no hacker, spy or malware can observe you or listen in on you. With just one single click, not only the camera, but also the microphone will be completely protected on your Macbook or iMac.


RegistryChangesView is a tool for Windows that allows you to take a snapshot of Windows Registry and later compare it with another Registry snapshot.
RegistryChangesView helps you compare the current Registry or with Registry files stored in a shadow copy created by Windows. When comparing 2 Registry snapshots, you can see the exact changes made in the Registry between the 2 snapshots, and optionally export the Registry changes into a standard .reg file of RegEdit.


Matched pair of vintage Capodimonte table lamps, each signed, as shown. Capodimonte's trademark is the bright colored glazes they used, and these lamps are cheerfully bright and impressive.
The lamps stand 22 inches from tabletop to socket top. As shown, the top of shade is 27 inches high. Lampshades are for display only and not available for sale.


Well now, I find the very early 'sodes irritating where Andy talks in a drawl.
Sometimes the drawl was a bit much, but I much prefer the first few seasons, with Ellie, the little fat mayor, a healthy Floyd, more folksy music....my happiest memories are back then. Didn't like it at all when Andy got too prim and proper with his speech, seemed like the slingshot effect. Anyway, there's room in Mayberry for everyone's feelings. We love 'em, or we wouldn't be here.
I know what you mean, Deborah. Love them all, but everyone has their favorites, hey?
Here is my list of least favorite episodes by season. The "stared" episodes are the episodes from that season that are hard for me to watch.
Note that some of these listed are the favorites of some. There is quite a bit of variety in tags due to the many different writers, the rapidly changing culture, and the general evolution of characters. You could almost classify it as 3 different shows, early Andy, the mid-series b/w era, and the counter-culture done Mayberry style.
I learn something new everyday....There are episodes after season five????
Funny - but you might not know it to watch reruns these days. Networks that show the color episodes are as scarce as hen's teeth!
Every now and then, I pull up a color episode on Netflix...but it's not very often. Something about seeing those green walls in the courthouse turns me off. Seems like a whole different world.
TVLand tries showing the color, Fife-less episodes once in a while, but they quickly figure out that only the crickets and a few faithful are watching, and switch back to the B&W episodes.
Being a late bloomer, I discovered MASH4077, the superb series of the '70s and early '80s. I am a little worn around the edges with TAGS.
I'm with you there Ralph. The only color episodes worth watching are the four where ol' Barn comes back to town.


text:
VRA gives 30 million cedis worth of books to schools
Accra, Dec. 15, GNA - The Volta River Authority (VRA) on Wednesday said it has donated a total of 23,000 exercise books valued at more than 30 million cedis to newly enrolled pupils in three districts and an orphanage since the beginning of the 2004/2005 academic year.
The books were distributed to class one pupils in Osudoku Traditional Area in Dangbe West, Asuogyaman and North Tongu Districts and NECTAR Home in Manya Krobo District.
A statement signed by Major J. B. Gyasi (rtd), Director of Public Affairs of VRA, said the donation was in fulfilment of the pledge made by the Authority under its Community Development Initiative (CDI) to lend support to communities in its operational areas in education and four other mutually agreed areas.
These are social infrastructure, income-generating projects, youth industrial attachment and cultural events.
It said the CDI of the Authority was the result of several months of dialogue and discussions with the communities to help meet some of their developmental needs and seek their welfare.
The Authority in making the presentations pledged to constantly make a difference in the lives of the pupils.
It said: "It takes everyone's involvement to ensure quality education for today's youth," and urged parents and teachers to work together to ensure that the children remained in school and attained academic excellence.
"Our primary goal is to make a difference in the lives of the children by bringing light into their hearts", the statement said. The Ghana Education Service (GES) officials noted that the impact of the donation transcended the lives of the pupils and the relief that it provided to parents and that it would further strengthen the bonds between VRA and the people.
VRA has long recognised the value of strong ties with communities in its operational areas. Over the years the communities have regularly received some form of support from the Authority, including free medical care to lakeside communities, reforestation programmes and provision of life jackets to promote safe lake transportation.


text:
Samoa Commision of Inquiry to review Village Fono Act
10:21 am on 2 August 2006
The Samoa government has appointed a Commission of Inquiry to review the Village Fono Act and its impact on decisions handed down by the Lands and Titles Court.
SBC TV reports that one of the Commission's objectives is to find common ground between the two for their decisions to be respected.
Another is to eliminate conflicts between decisions issued by the Lands and Titles Court and traditional leaders.
The Commission has three months to report back to cabinet
The former Minister of Police and Prisons was appointed last week to head the commission after another former government minister who was chairman stepped down because of ill health
Siouxsie Wiles 'really worried' about government's Omicron plan


text:
My Dynamite
Home Music Important Info About Rock Music
Important Info About Rock Music
Ramonita C Allen
I am going to start out by telling you some important information about rock music. Rock music is something that I absolutely love. Rock music is the genre that I listen to almost every single day. Rock music happens to be a very broad genre of very popular music which actually originated as rock 'n' roll in the United States of America, in the late 1940s and also in the early 1950s. It developed a huge range of different styles in the mid-1960s as well.
This was particularly focused in the United States of America and the United Kingdom. It has some deep-seated roots in the 1940s and 1950s. The rock 'n' roll style heavily draw in a lot of attention, and it had a lot of genres of blues, rhythm and blues and country music as well. Rock music also drew some strong numbers of other genres.
When it comes to instrumental hits, rock music completely centred on electric guitars, because it was usually used as part of a rock group with the help of electric bass, drums and one or two singers. If we are speaking generally, rock music is completely song-based music. It is a very diverse genre, as well. In comparison to pop music, the lyrics are often very romantic and they stress on love, but they also address a huge variety of other themes which are frequently political or even social as well.
If we are talking about the late 60s scene, classical rock became a huge sub-genre which emerged and captured the hearts of millions of people. You started getting hybrids of rock. Some of these were blues-rock, country rock, southern rock, jazz-rock and more.
One of the most amazing things was psychedelic rock as well. Psychedelic rock started developing, and it was influenced by counterculture hippie scenes.
Rock music has also done a fantastic job when it comes to embodying the vehicle for cultural and all kinds of social movements, which led to the major subcultures which included rockers in the United Kingdom and the hippie culture which spread throughout San Francisco in the United States of America, in the 1960s and 1970s.
The entire sound of rock music is traditionally centred on an amplified electric guitar, and it emerged in the modern form, in the 1950s when rock 'n' roll was really popular. It was also influenced by the sounds of electrical blues guitarists. The very sound of an electric guitar in rock music is typically and completely supported by the electric bass guitar, and it pioneered in jazz music, in the very same era. When you pair it with a piano or a quartet, you have got something wonderful.
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The top 5 Hard Rock Bands
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Some Facts About Rock That Will Surprise You
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When I was a kid I overheard a conversation my younger brother had with my mom…about me. They were in the next room, so I could still hear them. I guess my mom didn't know that, and she chose to handle the situation the way she did, unfortunately for me. He asked her if she thought I was pretty. I guess he was very little then and didn't have his opinion about things yet, so he asked a lot to learn about the world. Well, my mom did answer his question, but her answer haunts me even now. She paused for a second or two, I remember that, and then she told him that she thought I was…interesting.
Makes…you…think. And then think even more. And, maybe, realize we shouldn't be so harsh on our kids. After all, it's just an umbrella, figuratively speaking.
Another deep message today. Sounds simple, yet not many people give it enough thought.
Do you want love or blind obedience (also mistaken for"respect" by some parents) from your kids? If you want to be loved, then be the person worth loving. Would you love someone who constantly intimidates you, yells at you, spanks you, doesn't respect your opinion, and only wants you to follow everything that person says, all the time? Would you, honestly, be able to love someone like that? Then don't be that way with your own kids. Be someone they would look up to because they want to, not because they are forced to. Be someone they would enjoy spending time with, someone they would feel like they can trust, because they know you won't harm them, and will understand and support them. Be someone…you would love yourself if you were in your child's shoes. Be someone who deserves love.
"The American Psychoanalytic Association (APsaA) condemns the use of physical punishment (corporal punishment) in the discipline of children and recommends alternative methods that enhance children's capacities to develop healthy emotional lives, tolerate frustration, regulate internal tensions, and behave in socially acceptable ways.
When I was a child, and then later a teenager, my mom would always stress that she was my parent, not my friend, so I shouldn't see her as one, treat her as one, and talk to her as one. Of course, this was mentioned whenever there was a disagreement and she was unhappy with me, and she clearly used the word "friend" as something very bad. But it always puzzled me. I loved my friends, they were my world, so I hated whenever my mom would say such hurtful things, because I felt like by her attitude towards friendships she insulted my friends, too.
And the saddest part is that I always felt envious of families where children and parents were very close, as close as I was with my friends.


The 25th Annual Red Hook Fest, the FREE live music and dance festival on the Brooklyn waterfront, will be June 1 and 2, 2018! This year's theme is Artist as Activist, and we're happy to bring out artists, community organizations, and partners focused Featuring community workshops, free resources, family activities, games, face painting, and world-class performers, Red Hook Fest is fun for the whole family.
We have a stellar line-up of performers, including Ronald K. Brown/ EVIDENCE!


Hello friends, as you know when we browse something, we need a internet connection, it may be 2G or 3G or 4G.
Sometime, there are least people who annoys you, disturbs you repeatedly or when you travel via Flight, you have to switch off your smartphone or you have to enable the Flight mode or Airplane mode.
Don't worry , I am here to help you . In this article, I will share some interesting Tips & Tricks by which you can again use your internet connection in Airplane mode or flight mode too ?
Before knowing that trick, let me explain you what the airplane mode means !
What does Airplane mode refer ?
Airplane mode, airplane mode, flight mode, offline mode, or standalone mode is a setting available on many smartphones, portable computers, and other electronic devices that, when activated, suspends radio-frequency signal transmission by the device, thereby disabling Bluetooth, telephony, and Wi-Fi.
So, as you read, it's impossible to do call or use internet connection in Airplane mode?
But, just read this below steps and you can know the Tips & Tricks for using Internet use in Airplane mode .
How to call and use internet in Airplane or Flight Mode ?
● Next you can see a interface like this .
● You can see like this interface next .
● Then enable only 'Mobile Radio Power' by slide right .
Finally, you did it. Now you can call or use internet in Airplane mode or flight mode.
Also Read : How to Protect your Smartphone from Theft or Loss ? 100% Working !!


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Home / Records / Oldest F1 winners
Oldest F1 winners
The table below shows the age of every F1 race winner when they won their last Grand Prix.
Last win
1 (ITA) Luigi Fagioli 53 years, 0 months, 22 days 1951 France
2 (ITA) Giuseppe Farina (WC) 46 years, 9 months, 3 days 1953 Germany
3 (ARG) Juan Manuel Fangio (WC) 46 years, 1 months, 11 days 1957 Germany
4 (ITA) Piero Taruffi 45 years, 7 months, 6 days 1952 Switzerland
5 (AUS) Jack Brabham (WC) 43 years, 11 months, 5 days 1970 South Africa
6 (USA) Sam Hanks 42 years, 10 months, 17 days 1957 Indianapolis 500
7 (GBR) Nigel Mansell (WC) 41 years, 3 months, 5 days 1994 Australia
8 (USA) Lee Wallard 40 years, 8 months, 23 days 1951 Indianapolis 500
9 (FRA) Maurice Trintignant 40 years, 6 months, 18 days 1958 Monaco
10 (GBR) Graham Hill (WC) 40 years, 3 months, 3 days 1969 Monaco
11 (CHE) Clay Regazzoni 39 years, 10 months, 9 days 1979 Britain
12 (ARG) Carlos Reutemann 39 years, 1 months, 5 days 1981 Belgium
13 (FIN) Kimi Raikkonen (WC) 39 years, 0 months, 4 days 2018 USA
14 (BRA) Nelson Piquet (WC) 38 years, 9 months, 16 days 1991 Canada
15 (ITA) Riccardo Patrese 38 years, 6 months, 8 days 1992 Japan
16 (USA) Mario Andretti (WC) 38 years, 5 months, 30 days 1978 Netherlands
17 (FRA) Alain Prost (WC) 38 years, 5 months, 1 days 1993 Germany
18 (USA) Rodger Ward 38 years, 4 months, 20 days 1959 Indianapolis 500
19 (GBR) Damon Hill (WC) 37 years, 11 months, 13 days 1998 Belgium
20 (AUT) Gerhard Berger 37 years, 11 months, 0 days 1997 Germany
21 (FRA) Jean-Pierre Jabouille 37 years, 10 months, 16 days 1980 Austria
22 (FRA) Jacques Laffite 37 years, 10 months, 6 days 1981 Canada
23 (ITA) Vittorio Brambilla 37 years, 9 months, 6 days 1975 Austria
24 (DEU) Michael Schumacher (WC) 37 years, 8 months, 28 days 2006 China
25 (NZL) Denny Hulme (WC) 37 years, 6 months, 26 days 1974 Argentina
26 (BRA) Rubens Barrichello 37 years, 3 months, 21 days 2009 Italy
27 (FIN) Keke Rosberg (WC) 36 years, 10 months, 28 days 1985 Australia
28 (GBR) Lewis Hamilton (WC) 36 years, 10 months, 28 days 2021 Saudi Arabia
29 (GBR) John Watson 36 years, 10 months, 23 days 1983 USA West
30 (AUT) Niki Lauda (WC) 36 years, 6 months, 3 days 1985 Netherlands
31 (USA) Dan Gurney 36 years, 2 months, 5 days 1967 Belgium
32 (AUS) Mark Webber 35 years, 10 months, 11 days 2012 Britain
33 (USA) Bill Vukovich 35 years, 5 months, 18 days 1954 Indianapolis 500
34 (GBR) Johnny Herbert 35 years, 3 months, 1 days 1999 Europe
35 (USA) Richie Ginther 35 years, 2 months, 19 days 1965 Mexico
36 (FRA) Rene Arnoux 35 years, 1 months, 24 days 1983 Netherlands
37 (ITA) Alberto Ascari (WC) 35 years, 1 months, 10 days 1953 Switzerland
38 (CHE) Jo Siffert 35 years, 1 months, 8 days 1971 Austria
39 (FRA) Jean-Pierre Beltoise 35 years, 0 months, 18 days 1972 Monaco
40 (AUS) Alan Jones (WC) 34 years, 11 months, 15 days 1981 Caesars Palace
41 (FRA) Patrick Depailler 34 years, 8 months, 20 days 1979 Spain
42 (USA) Peter Revson 34 years, 6 months, 27 days 1973 Canada
43 (SWE) Ronnie Peterson 34 years, 5 months, 30 days 1978 Austria
44 (USA) Phil Hill (WC) 34 years, 4 months, 21 days 1961 Italy
45 (GBR) Jackie Stewart (WC) 34 years, 1 months, 25 days 1973 Germany
46 (GBR) Eddie Irvine 33 years, 11 months, 7 days 1999 Malaysia
47 (FRA) Patrick Tambay 33 years, 10 months, 6 days 1983 San Marino
48 (BRA) Ayrton Senna (WC) 33 years, 7 months, 17 days 1993 Australia
49 (GBR) John Surtees (WC) 33 years, 6 months, 30 days 1967 Italy
50 (DEU) Wolfgang von Trips 33 years, 2 months, 11 days 1961 Britain
51 (ITA) Giancarlo Fisichella 33 years, 2 months, 5 days 2006 Malaysia
52 (BEL) Thierry Boutsen 33 years, 0 months, 30 days 1990 Hungary
53 (FIN) Mika Hakkinen (WC) 33 years, 0 months, 2 days 2001 USA
54 (ITA) Ludovico Scarfiotti 32 years, 10 months, 17 days 1966 Italy
55 (GBR) Jenson Button (WC) 32 years, 10 months, 6 days 2012 Brazil
56 (MEX) Sergio Perez 32 years, 8 months, 6 days 2022 Singapore
57 (USA) Jimmy Bryan 32 years, 4 months, 14 days 1958 Indianapolis 500
58 (DEU) Heinz-Harald Frentzen 32 years, 3 months, 25 days 1999 Italy
59 (DEU) Sebastian Vettel (WC) 32 years, 2 months, 19 days 2019 Singapore
60 (AUS) Daniel Ricciardo 32 years, 2 months, 11 days 2021 Italy
61 (FIN) Valtteri Bottas 32 years, 1 months, 12 days 2021 Turkey
62 (GBR) David Coulthard 31 years, 11 months, 10 days 2003 Australia
63 (USA) Johnnie Parsons 31 years, 10 months, 26 days 1950 Indianapolis 500
64 (GBR) Stirling Moss 31 years, 10 months, 20 days 1961 Germany
65 (USA) Jim Rathmann 31 years, 10 months, 14 days 1960 Indianapolis 500
66 (GBR) Jim Clark (WC) 31 years, 9 months, 28 days 1968 South Africa
67 (ESP) Fernando Alonso (WC) 31 years, 9 months, 13 days 2013 Spain
68 (ARG) Jose Froilan Gonzalez 31 years, 9 months, 12 days 1954 Britain
69 (GBR) Peter Gethin 31 years, 6 months, 15 days 1971 Italy
70 (ITA) Luigi Musso 31 years, 5 months, 25 days 1956 Argentina
71 (CAN) Gilles Villeneuve 31 years, 5 months, 3 days 1981 Spain
72 (GBR) Innes Ireland 31 years, 3 months, 26 days 1961 USA
73 (DEU) Nico Rosberg (WC) 31 years, 3 months, 12 days 2016 Japan
74 (FRA) Jean Alesi 31 years, 0 months, 0 days 1995 Canada
75 (NZL) Bruce McLaren 30 years, 9 months, 10 days 1968 Belgium
76 (USA) Pat Flaherty 30 years, 4 months, 24 days 1956 Indianapolis 500
77 (MEX) Pedro Rodriguez 30 years, 4 months, 20 days 1970 Belgium
78 (BRA) Carlos Pace 30 years, 3 months, 20 days 1975 Brazil
79 (ITA) Alessandro Nannini 30 years, 3 months, 15 days 1989 Japan
80 (FRA) Didier Pironi 30 years, 3 months, 7 days 1982 Netherlands
81 (GBR) James Hunt (WC) 30 years, 1 months, 24 days 1977 Japan
82 (COL) Juan Pablo Montoya 30 years, 0 months, 5 days 2005 Brazil
83 (ITA) Jarno Trulli 29 years, 10 months, 10 days 2004 Monaco
84 (FRA) Olivier Panis 29 years, 8 months, 17 days 1996 Monaco
85 (ZAF) Jody Scheckter (WC) 29 years, 7 months, 11 days 1979 Italy
86 (SWE) Jo Bonnier 29 years, 4 months, 0 days 1959 Netherlands
87 (GBR) Mike Hawthorn (WC) 29 years, 2 months, 26 days 1958 France
88 (USA) Bob Sweikert 29 years, 0 months, 10 days 1955 Indianapolis 500
89 (ITA) Lorenzo Bandini 28 years, 8 months, 2 days 1964 Austria
90 (ITA) Michele Alboreto 28 years, 7 months, 12 days 1985 Germany
91 (BRA) Emerson Fittipaldi (WC) 28 years, 7 months, 7 days 1975 Britain
92 (DEU) Jochen Mass 28 years, 6 months, 28 days 1975 Spain
93 (SWE) Gunnar Nilsson 28 years, 6 months, 16 days 1977 Belgium
94 (AUT) Jochen Rindt (WC) 28 years, 3 months, 15 days 1970 Germany
95 (DEU) Ralf Schumacher 28 years, 0 months, 6 days 2003 France
96 (ESP) Carlos Sainz 27 years, 10 months, 2 days 2022 Britain
97 (FRA) Francois Cevert 27 years, 7 months, 8 days 1971 USA
98 (BEL) Jacky Ickx 27 years, 6 months, 29 days 1972 Germany
99 (BRA) Felipe Massa 27 years, 6 months, 8 days 2008 Brazil
100 (GBR) Tony Brooks 27 years, 5 months, 8 days 1959 Germany
101 (VEN) Pastor Maldonado 27 years, 2 months, 4 days 2012 Spain
102 (ITA) Elio de Angelis 27 years, 1 months, 9 days 1985 San Marino
103 (FIN) Heikki Kovalainen 26 years, 9 months, 15 days 2008 Hungary
104 (GBR) Peter Collins 26 years, 8 months, 11 days 1958 Britain
105 (ITA) Giancarlo Baghetti 26 years, 6 months, 7 days 1961 France
106 (CAN) Jacques Villeneuve (WC) 26 years, 5 months, 19 days 1997 Luxembourg
107 (NLD) Max Verstappen (WC) 25 years, 1 months, 21 days 2022 Abu Dhabi
108 (FRA) Esteban Ocon 24 years, 10 months, 15 days 2021 Hungary
109 (GBR) George Russell 24 years, 8 months, 29 days 2022 Sao Paulo
110 (MCO) Charles Leclerc 24 years, 8 months, 24 days 2022 Austria
111 (FRA) Pierre Gasly 24 years, 6 months, 30 days 2020 Italy
112 (POL) Robert Kubica 23 years, 6 months, 1 days 2008 Canada
113 (USA) Troy Ruttman 22 years, 2 months, 19 days 1952 Indianapolis 500


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Q: Why are headings and paragraphs considered as clickable elements (HTML) I am trying to make my webapp (created with Python Dash) more accessible, e.g. for users relying on screen readers. In order to test my webapp I use the Accessibility Inspector built into Firefox. Here I run into issues concerning focusability and interactivity of elements which are supposed to show text (e.g. headings and paragraphs).
First I created my elements like this:
    html.H1(
     children="this is my header"
    )

    html.P(
     children="this is text"
    )`

In these cases the Accessibility Inspector yields the following warning:
Clickable elements must be focusable and should have interactive semantics
In order to resolve this, I added 'tabIndex' to my elements:
    html.H1(
     children="this is my header",
     tabIndex='0'
    )

    html.P(
     children="this is text",
     tabIndex='0'
    )

This eliminated one part of the warning. Now I got this warning:
Focusable elements should have interactive semantics
From what I gathered on accessibility so far it is bad practice to give non interactive elements like headings a 'tabIndex'. So my second approach is probably already going in the wrong direction.
Can you please tell me how to deal with the first warning instead? And why are headings and paragraphs considered as clickable elements? They do not contain a link or anything else.
Update:
If I take a look at the HTML in Firefox, the header looks like this:
screenshot HTML
Solution: I asked my question in the Plotly Community Forum (https://community.plotly.com/t/how-to-remove-events-from-dash-html-components-to-avoid-misinterpretation-by-screen-readers/70477) as well. They pointed me towards the dash mantine components library (https://www.dash-mantine-components.com/), which includes dmc.Title and dmc.Text which can be used instead of html.H1-H6 and html.P. This resolves my issue.

A: I looked at some sample Dash applications, https://dash.gallery/dash-clinical-analytics/, and indeed the headings on that demo are "clickable".

"Clinical Analytics" is an <h5> and "Welcome to the Clinical Analytics Dashboard" is an <h3>.  Both have an event handler for the click event.

That will cause some screen readers to say those elements are "clickable".  Here's what NVDA says when I use the H key to navigate to the headings:

*

*"Clinical Analytics, heading, clickable, level 5"

*"Welcome to the Clinical Analytics Dashboard, heading, clickable, level 3"
The screen reader is trying to help the user let them know that an event handler is on that element and that it can be clicked on.  However, headings are not normally considered interactive elements so it'll be confusing.
This seems like a bug in Dash.
The error you're getting, "Clickable elements must be focusable and should have interactive semantics" is accurate.  It has two parts:

*

*"elements must be focusable" - anything that you can interact with using a mouse should be interactable (word?) with the keyboard.  In order to interact with the element, you first have to be able to get your keyboard focus to it, thus the error message.

*"elements should have interactive semantics" - when a screen reader user navigates to an interactive element, they should hear the role of that element and that role should convey that the element is an interactive element.  The headings do have semantics, NVDA says they're "headings", as noted above, but the error message says it should be "interactive semantics", not just "semantics".
All this info doesn't explain how to fix your problem but I wanted to post the "why" of the error message, and I couldn't fit all this into a simple comment :-)


Ann Sansom of the Poetry Business ran a residential Poetry week at the Almassera Vella in June and it resulted in a happy coda as she invited me to read at the Wordsworth Trust in Grasmere and join a workshop there. Ann's courses at the Almassera Vella have proved the birthplace of a good deal of published and prize-winning poetry — her methods almost force quality work out of you.
Peter Sansom ran the Grasmere workshop on similarly inspiring lines and and as the sun set over the fells, we indulged in a Wordsworth/Coleridge 'walk and talk' afterwards.
This summer we've switched the pool system to salt water and as a result have beautifully clean and clear water seemingly permanently. As the water has a tenth the salt of the sea it isn't discernible as a taste and we no longer have that hint of chlorine.
It also seems to resist algae. All we have to worry about is occasional Sahara dust after rain storms.
Last year's haul of 226 litres of extra virgin oil from our Valero trees, probably won't be matched this year as the chilly Spring has reduced the harvest. The Blanqueta trees however are laden. We have a party coming on November 2nd to help in the gathering. 'Milking' an olive tree very therapeutic – just taking your hands down a branch and letting the olives fall onto the 'manta' below. Old-fashioned thrashing is therapeutic too, but in a different way. You have to be careful not to damage the tree overly. After gathering, the trick is to get the olives as quickly as possible to the press lower down the valley. We sold most of last year's surplus to a restaurant. I suspect there'll be enough for just us this year.
We had our eighty trees pruned earlier this year – 'so a swallow can fly 'atween the branches'.
Opened in 2002, the Almàssera Vella was designed as a home and as a centre for retreats and courses in Creative Writing, Art, Photography and Walking.


Disasters aren't an everyday occurrence but they can strike anywhere. It's never require to evacuate your home, but in case you are living a floodplain, on a coastal area, or near an earthquake fault, most likely be incorrect. The preparation you do in advance is critical to your family's safety, but don't neglect to organize for your pets, also. It will reward you with peace of mind knowing you planned as thoroughly as possible, you are equipped, therefore your family and pets the excellent regarding surviving the disaster – hurricane, flood, wildfire, hazardous material spills too as man-made disaster.
"We also had a country where people were people of faith. What amount of people of faith fairly substantially exceeded those have been just in things on their own. And it was that sense of 'yes I'm my brother's keeper'. We did get rid of the injured; we did take good the indigent. Those everyone was never in danger in america. And even the extraordinarily wealthy folks our nation – the Carnegies, the Mellons, the Kelloggs, the Fords, Rockefellers, Vanderbilts – they built universities and charitable foundations but more importantly they took their wealth and built the infrastructure one's nation. Plus they also built up factories and textile mills." Carson argued.
But stop worrying. You can augment that "bring some money to help" project along with a few simple resources. One option is achieve out to some local support group arrive talk onto your children about disaster relief charity. Cleveland has unique Red Cross chapter. Could possibly reach out to them for information. Did you also know that John Carroll University in University Heights has a seismograph on-page? This could provide valuable information on earthquakes.
Senate Democrats voiced cautions optimism that the Republican House will perform the right task. "It is difficult to see how House Republicans could reject this proposal, given enthusiasts vote it received involving Senate," said Sen. Chuck Schumer (D-NY) according to your Hill.
The International Alert Academy is an incomparable Christian training and service organization. IAA encompasses several programs looking at the base in East Colorado front range. The Academy teaches survival, search and rescue, and in the news skills for air and land crisis situations. According to the IAA website, its goal is "to prepare generations to be Followers of Christ." It adds, "We equip of those that have tools to higher prepare them for specific callings God has positioned each of their total lives." Cost of of a 9-week bootcamp program is ,300, with an additional 0-,200 for instruments.
The Whitehead Scholarship Program takes a special interest in those attempting go in the health occupational. Most of the Lettie Pate Whitehead scholarships go toward undergraduate higher education, but they lean towards students who are enrolled in health mastering. A large number of its monetary gifts support learning in the medical, nursing, and allied health care fields. If you've always thought about being a nurse this group could allow you fund the right.
World Vision's raised its tornado response appeal to million to meet additional needs in Missouri and Minnesota. To support these relief efforts, text TORNADO to 20222.


text:
Indiana University South Bend provides free Wi-Fi to public in response to coronavirus
Allie Kirkman
SOUTH BEND — Indiana University is providing free, 24-hour Wi-Fi access to students and the general public who may not have internet connectivity because of coronavirus- related closures.
IU's University Information Technology Services networks division has set up "lot hot spots" in parking lots on eight IU campuses, including South Bend.
The hot spots will allow users to maintain social distancing while accessing the internet from their cars.
"I am so proud of the creativity and innovation that Indiana University is showing to supply Hoosiers with free and reliable high-speed internet access as we work together to combat the spread of COVID-19," Suzanne Crouch, Indiana lieutenant governor, said in a news release.
Those with IU affiliations can access the university's IU Secure and Eduroam networks at all "lot hot spots." The general public can connect to the IU Guest network.
Participating locations will have directional signage to help people find their connection. Wi-Fi "lot hot spots" can be found at:
IU South Bend: Student Activities Center parking lot
IU Bloomington: Orange lot between Memorial Stadium and Assembly Hall
IUPUI: Lot 92, N. Blackford St.
IU East: Tom Raper Hall parking lot
IU Kokomo: Main Building, Havens lot next to the Well House
IU Northwest: Moraine Student Center, parking lot 2
IU Southeast: Knobview Hall, Hickory parking lot
IUPUC: Campus Center, Arnold Street parking lot
All IU face-to-face classes have been suspended and students and faculty are preparing to transition to virtual learning for the remainder of the spring semester. Online classes start next week.
IU South Bend officials are working to make campus technology resources available for students who may not have access to the technology at home or who are not familiar with taking online classes, according to the university's website. Students will have access to certain on-campus computer labs with controls put in place for recommended social distancing. Hours and locations are still being worked out.
Students can find more information on online learning at www.iusb.edu/covid-19-faq.html.


White wrought-iron bed and wicker furniture with ivy accents and wallpaper. Private bathroom has small antique claw-foot tub with shower. Original sun room. Has TV/DVD. Lodging is airy and bright. Private deck with view of the bluff. Faces south and west.
Contact us for availability and reservations.


The classic tale between Man vs Jungle returns to the big screen April 15th after years of anticipation of a improved visual experience. The original story written by Rudyard Kipling was made by Disney as an animated film back in 1967, a film where most of the children growing up still know today. It took almost 50 years for Disney to revisit this timeless classic, but they did so with great intention. As 3D technology is at its best, Disney took a chance with Director Jon Favreau (Iron-Man trilogy) and re-made this film with a mixture of Digital Animation and Real Life to create a masterpiece all over again.
The Jungle Book has some of the best Hollywood can offer right now, Bill Murry as Baloo, Ben Kingsley as Bagheera, Idris Elba as Shere Khan, Lupita Nyongo as Raksha, Scarlett Johansson as Kaa, Christopher Walken as King Louie, Neel Sethi as Mowgli and Giancarlo Esposito as Akela to name a a few. Below are the Cast members and their Animal counter parts.


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You are at:Home»News»Airport»Swedavia issues green bond loan
Swedavia issues green bond loan
By Tara Craig	 December 10, 2019 No Comments
Swedavia has become one of the first airport operators in the world to issue a green bond loan to fund projects and investments in climate change adaptation and sustainability.
The investments will include projects that support Swedavia's long-term strategy and that contribute to the United Nations' Sustainable Development Goals and the Paris Agreement's long-term temperature goal. The investments will be made under the Green Bond Framework that Swedavia launched in October 2019, developed in partnership with banks SEB and Swedbank.
"Swedavia's ambition is to be a world leader in developing airports with the least possible climate impact. We have now secured additional funding for our continued adaptation journey and for our vision of climate-smart airports and the transformation of aviation. The great investor interest in the loan was thus very gratifying," says Jonas Abrahamsson, Swedavia's president and CEO.
The framework was subject to an independent external assessment by the Center for International Climate and Environmental Research (CICERO). Its investment categories include: green buildings and infrastructure; energy efficiency; renewable energy; pollution prevention and control; and clean transportation.
In its assessment, CICERO took into consideration the fact that Swedavia's operations could lead to increased emissions but noted that Swedavia is a role model for airports globally in terms of climate change adaptation.
Swedavia's goal is to have zero carbon dioxide emissions from its own operations at all 10 of its airports by 2020. This will be achieved in part by investing in renewable fuels and the electrification of ground vehicles and equipment. By 2025, 5% of all fuel used to refuel aircraft at Swedish airports will be fossil-free, according to the operator. All of Swedavia's airports have been certified at the highest level under Airport Carbon Accreditation's environmental standards.
The unsecured Skr1bn (US$105m) green bond loan has a maturity of 5.25 years and a fixed interest rate of 0.89%. Swedavia intends to apply to have the green bonds listed on Nasdaq Stockholm's corporate bond list.
Tara Craig
Tara has worked for UKi Media & Events since 2013, initially as a freelancer. She has been a journalist for over a decade and has worked for a range of publications, including Personnel Today, Management Today and The Grocer.
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WATERLOO, Ont. (Monday, April 11, 2016) – A new resource is available that offers easy recipes featuring Ontario-grown products to promote healthy aging. The resource was created by a research team at the University of Guelph in collaboration with Agri-food for Healthy Aging (A-HA) and the Schlegel-UW Research Institute for Aging (RIA).
Nutrition plays an important role in our health, and this is especially true as we get older. The risk of developing a number of chronic diseases increases with age, and nutrition can influence this risk. Older adults can also experience nutritional challenges such as taste changes and limitations in their ability to prepare healthy foods. In 2013, Statistics Canada reported that 34% of people ≥65 years old who are living in community are at nutritional risk.
Eating a variety of nutrient-rich foods is one strategy to help ensure proper nutrition. Fortunately, Ontario produces a large variety of foods that offer health benefits, making it easier for older adults to take a 'food-first' approach to healthy aging.
A research team, led by A-HA research scientist Alison Duncan, PhD, RD (Professor, Human Health and Nutritional Sciences, University of Guelph), developed a Recipe Resource for Healthy Aging that features Ontario-grown foods and their benefits for health as we age.
The resource features 50 recipes including beverages, breakfasts, snacks, soups and stews, salads, sides, mains, and desserts. The evidence-based age-related health benefits of the Ontario-grown foods are highlighted, and cooking tips are provided to offer ideas for ingredient substitutions and strategies to make preparation easier. Testimonials from older adults and Ontario farmers appear throughout.
This exciting new resource is now freely available on the A-HA website (www.aha.the-ria.ca).
Agri-food for Healthy Aging (A-HA) is a collaborative research and knowledge translation group that aims to realize opportunities for Ontario's agri-food and health sectors to improve the health and well-being of older adults through the innovative use of food. A-HA was created in 2007 through the efforts of MaRS Landing, Schlegel-UW Research Institute for Aging (RIA), and the Universities of Guelph and Waterloo. It is 1 of 10 theme areas within the RIA.
The RIA was created in 2005 as a senate-approved research institute at the University of Waterloo, and subsequently became a public foundation with charitable status in 2006. RIA's core partners are the University of Waterloo, Conestoga College and Schlegel Villages. The RIA conducts practice-relevant research to enhance the care, health and wellness of older adults in community and congregate environments. The Schlegel Villages provide voluntary and vibrant living research environments and living classrooms. The best of what is learned is then disseminated broadly to benefit older adults everywhere. For more information go to www.the-ria.ca.


Change begins with understanding and understanding begins by identifying oneself with another person, in a word empathy. Alfred Dondo was formed to make sure that every child experiences a full life regardless of disability of socio-economic background. They advocate on behalf of disabled children and children in need. They work with donors to help and support families that have disabled children. This helps save children from future poverty, health issues and feelings of inadequacy. With the right support children can build the confidence and independence to be the leaders of their own lives.It is about supporting young people to reach their potential. Every child regardless of their story needs support to ensure a brighter future.


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Andrew Azar on the top floor of the planned entertainment and food hotspot on the waterfront in downtown Kingston.
Under a plan developed by businessman Andrew Azar and his partners, a new entertainment hotspot should have by now be fully operational on the Kingston waterfront to welcome the hundreds of persons expected to travel there for the Urban Development Corporation (UDC) annual Fireworks on the Waterfront.
But the scheduled mid-November opening of the facility that was shuttered 17 years ago has been pushed back to late February, and Azar is blaming the UDC for the delay.
According to Azar, the investors have lost hundreds of thousands of dollars as a result of the UDC putting a stop order on the work to develop the area into a spot for food and entertainment.
"There were some requirements by the UDC during the planning stages, plans and stuff that we had submitted to them that in their opinion were not of the adequate standards that they needed," Azar told The Sunday Gleaner.
"So we had to redo the plans, and at that point they had issued us some sort of stop order until the plans were up to their standards," added Azar.
He said after much effort, the partners were able to comply with the UDC's stipulations, and last week they were issued a letter giving permission for work to resume.
"However, it has hurt me financially as I have lost many rentals for November and December," said Azar.
"But they are going to say whatever they needed was very important to the development. My argument is that we could have done it concurrently; so I could have got my plans made while holding an event, but they gave me a stop order and it was very frustrating.
"We are investors, we are investing more than $60 million down there, and I don't think really we were treated like investors. But it is what it is, and whatever we weren't compliant with we were told, and we have now become compliant," Azar added.
He told our news team that in addition to the loss of potential earnings, the partners lost hundreds of thousands dollars' worth of plants, which persons stole during the lull in work, while ceiling fans valued at some quarter million dollars were damaged by wind.
Two years ago, the Urban Development Corporation signed over the run-down Victoria Pier to Yosamini Holdings Limited, under a lease agreement, for an initial period of 25 years.
The company, in which Azar and Barry Gardener are partners, set about redeveloping the complex, which spans 1,963 square metres on three levels.
The first floor is slated to house a sports bar, which is likely to be operated by Ribbiz, while the second floor will have a branch of the renowned seafood establishment Gloria's, which is renting the space to replicate the Port Royal experience. There are also plans to have a Devon House I'Scream, an Island Coffee Shop, a pizza parlour and a natural juice outlet.
"People can rent the roof for parties and weddings that are affordable for lower- and middle-income persons, and then have the reception on the first floor," said Azar.
"We are going to try and start with breakfast and then have lunch, and then go right through to about 8 to10 p.m., depending on how people view the area. There will also be brunch on a Sunday, and on a Sunday we also want to try and bring back that family thing with the vintage singers to try and bring back a little bit of entertainment on the waterfront."
Azar acknowledged that it will be an uphill task to try and get persons to come downtown in the evenings, but he is promising very tight security.
He said arrangements are also being made with the Kingston and St Andrew Municipal Corporation to facilitate the development.


Progesterone injections and a rant!
Anyone else going to receive progesterone injections during your pregnancy? I received it last time and I know that is why I was able to carry to 38 weeks. Now this time around I have anthem bcbs abd they are telling me I have to pay $625 a month! I just was told last week at work that I'm not allowed to work anymore because I have lifting restrictions from my dr and my employer which is a hospital and they are not required to offer light duty positions. So now I'm not working and have all these medical bills associated with a high risk pregnancy, a son woth a heart defect that is always sick or having some type of procedure and paying for speech therapy. To top it off my mom, who has been battling cancer off and on for 25 years, was just diahnosed with lung cancer and throat cancer. She was still recovering from tongue cancer from last year. Yikes, I'm in over my head! Thankfully, I have an extraordinary husband who is always by my side. Just needed to rant and maybe I will feel better. If you believe in praying I would appreciate all the prayers I can get. I know this will all work out.


The steam-sauna was invented in the Nordic countries and includes a stay in a cabin equipped with wooden benches where the temperature is raised to about 80-100 C° and humidity at 10-30%. You will start with dry air and then will experience a overheated steam obtained by pouring water over hot stones. This practice is then followed by a cold water shower. The most obvious effect of the high temperatures of the steam-sauna is diaphoretic: the heat helps to relax the muscles, to perspire and to eliminate toxins.


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An Aerospace Powerhouse
Airbus is one of the great Welsh manufacturing success stories of the age, with the world-class facilities in North Wales setting the global standard in aerospace manufacturing.
Broughton is a powerhouse for Airbus: the aircraft manufacturer produces in excess of 1,000 wings a year from a site with a workforce of more than 6,000 people. The Welsh home of aviation classics like De Havilland's Comet and the
Mosquito continues to thrive. An overall investment of £2 billion over the past 15 years has helped to ensure an exciting future for one of the most prestigious businesses in Wales. Steve Thomas, the Government Affairs Executive for Airbus UK, says the mood is buoyant.
"Airbus has had a presence at Broughton since 1939, when we were created as a shadow war factory. We're primarily involved in manufacturing and engineering, but we've invested significantly in the wider supply chain, which employs around 2,000 people. This is a fantastic modern setting. Adjacent to the west factory we've got a business park with three suppliers. And we're very proud of our skilled workforce, which extends to over 6,500 people. Today, Wales offers exactly what Airbus requires in terms of the infrastructure, surrounding locality, skilled workforce and the facilities across the site and its 750 acres. More than 100,000 people are dependent on the work we generate, and it contributes more than £2 billion to the UK economy each year, so we're riding on a high.
"We've got future bookings extending over ten years. There's a great level of optimism associated with that order book and the future prospects we have. When we look up in the sky, it's a great feeling to know that we've contributed in some shape and fashion to that success story.
"My advice to other companies looking at operating in Wales is, 'come and join us'. We are the envy of our European partners in terms of what we've got here in Wales and the relationship we've got with Welsh Government and how supportive they have been. It's a great, mature relationship that's developed over a number of years.
"A close relationship with Welsh Government gives us access to decision makers at ministerial level quickly. And if we want advice and support we can just pick up the phone."
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