Angelman syndrome signs and symptoms include: 
Developmental delays, including no crawling or babbling at 6 to 12 months
Intellectual disability
No speech or minimal speech
Difficulty walking, moving or balancing well
Frequent smiling and laughter
Happy, excitable personality
Sucking or feeding difficulty
Trouble going to sleep and staying asleep
 People who have Angelman syndrome may also show the following features: 
Seizures, usually beginning between 2 and 3 years of age
Stiff or jerky movements
Small head size, with flatness in the back of the head
Tongue thrusting
Hair, skin and eyes that are light in color
Unusual behaviors, such as hand flapping and arms uplifted while walking
Sleep problems
Curved spine (scoliosis)
