Wilson's disease is present at birth, but signs and symptoms don't appear until the copper builds up in the brain, liver or other organ. Signs and symptoms vary depending on the parts of your body affected by the disease. They can include: 
Fatigue, lack of appetite or abdominal pain
A yellowing of the skin and the whites of the eye (jaundice)
Golden-brown eye discoloration (Kayser-Fleischer rings)
Fluid buildup in the legs or abdomen
Problems with speech, swallowing or physical coordination
Uncontrolled movements or muscle stiffness
 When to see a doctor Make an appointment with your doctor if you have signs and symptoms that worry you, especially if a family member has Wilson's disease.