Signs and symptoms of neuroblastoma vary depending on what part of the body is affected. Neuroblastoma in the abdomen — the most common form — may cause signs and symptoms such as: Neuroblastoma in the abdomen 
Abdominal pain
A mass under the skin that isn't tender when touched
Changes in bowel habits, such as diarrhea or constipation
 Neuroblastoma in the chest may cause signs and symptoms such as: Neuroblastoma in the chest 
Wheezing
Chest pain
Changes to the eyes, including drooping eyelids and unequal pupil size
 Other signs and symptoms that may indicate neuroblastoma include: 
Lumps of tissue under the skin
Eyeballs that seem to protrude from the sockets (proptosis)
Dark circles, similar to bruises, around the eyes
Back pain
Fever
Unexplained weight loss
Bone pain
