While the exact cause of depression isn't clear, research suggests that most mental disorders develop, at least in part, because of a chemical imbalance in the brain, and/or an underlying genetic predisposition.
Meskipun penyebab pasti depresi tidak jelas, tapi penelitian mengatakan kebanyakan penyakit mental berkembang setidaknya sebagian, karena ketidakseimbangan bahan kimia di dalam otak. dan/atau predisposisi genetik tersembunyi.