Research Scientist, Immunology - Cancer Biology
Employer Provided Salary:$100K-$140K
Research Scientist, Immunology - Cancer Biology
Location: Cambridge, MA
Kronos Bio seeks a highly motivated Research Scientist to join its drug discovery team located in Cambridge, MA. As a member of an interdisciplinary team, this individual will be expected to harness their strong background in immunology/immuno-oncology to help guide strategic scientific decisions and research program development. The applicant is expected to have a robust experimental skill set, an eagerness for learning, and contribute to a strong culture of teamwork and collaboration in a fast-paced environment.
Principal Duties and Responsibilities:
Provide functional area expertise in immunology/immuno-oncology as a member of the Biology team.
Work within project teams and across functional groups to drive key elements of the discovery and preclinical development of novel cancer immunotherapies.
Independently design, optimize, and execute flow cytometry-based immunological assays to characterize lead compounds and their effects on anti-tumor immune responses.
Use a repertoire of in vitro assays (ELISA, qPCR, Nanostring, western blotting) to further define the MOI of lead molecules and the biology of novel targets.
Identify and implement new experimental techniques as required to answer critical scientific questions and advance programs.
Use literature survey to solve specific research problems.
Actively contribute to a focused, team-oriented atmosphere providing assistance and/or guidance to colleagues when needed.
Maintain high standards of laboratory safety
Perform research in compliance with all applicable regulatory and guidelines, as informed by supervisor.
Qualifications:
PhD in immunology or related field with 0-2 years of industry or postdoctoral research experience (industry/biotech experience preferred).
Expertise in basic immunological techniques such as isolation and culture of primary cells, multi-color flow cytometry, and cytokine profiling.
Experience establishing ex vivo functional immune assays such as T cell proliferation, suppression, and cytotoxicity assays.
Extensive knowledge of T cell biology, including regulatory T cells, and mechanisms of immune suppression is a plus.
Ability to work independently and able to balance multiple tasks or projects.
Diligent with details and timely execution and delivery of high-quality results.
Familiarity with analysis of genomic and gene expression data sets.
Highly analytical mind, attention to detail, excellent organizational skills, and rigorous experimental record keeping using an ELN system are critical.
Collaborative, proactive and optimistic personality.
Interested candidates should forward a resume and cover letter to careers@kronosbio.com.
https://kronosbio.com/openpositions/
Kronos Bio, Inc., is dedicated to the research and development of first-in-class therapies that modulate historically “undruggable” cancer targets. Leveraging industry-leading research into high-throughput screening strategies for chemical modulators of transcription factors and other challenging targets in oncology, Kronos Bio utilizes its small molecule microarray (SMM) platform and extensive know-how in biological assay development to pursue novel therapies against some of the most important and intractable targets in cancer research .
Kronos Bio
Kronos Bio