Scientist, Pharmacometrics
$84K-$157K (Glassdoor est.)
Scientist, Pharmacometrics
Location


Agios Pharmaceuticals HQ

Job Code

1215

# of openings

1

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Scientist, DMPK/Pharmacometrics

Agios (agios.com) is a biopharmaceutical company committed to applying our scientific leadership in cellular metabolism to transform the lives of patients with cancer and rare genetic diseases. We are growing rapidly with an active research and discovery pipeline across both therapeutic areas. Agios has two approved oncology precision medicines and multiple first-in-class investigational therapies in clinical and/or preclinical development.

Agios Pharmaceuticals is searching for a dynamic Scientist to join our growing DMPK/Pharmacometrics team. The Scientist will be responsible for pharmacometric activities including data analysis planning, data analysis and interpretation for NCA, population PK/PD and exposure-response analyses for safety and efficacy.

Key Responsibilities
Prepares analysis plan for NCA, exposure-response analysis and population PK/PD modeling and simulation
Performs pharmacometric analyses and activities within assigned programs to yield high impact on critical decisions
Interprets and presents results and recommends appropriate actions
Drives the development and execution of the pharmacometric strategy of clinical development teams
Provides insightful regulatory strategy for pharmacometric support of drug filings and is responsible for the respective sections of regulatory documents
Develops and maintains strong knowledge of best regulatory practices and pharmacometric analysis methodology
Contributes to cross line functional collaboration
Develops and maintains scientific knowledge in pharmacometrics, publishes manuscripts and posters, presents at scientific conferences and other scientific forums internally and externally
Minimum Requirements
Applicants should possess a PhD or Masters in pharmacometric, clinical pharmacology, pharmacokinetics, pharmaceutical sciences, pharmacy, biomedical engineering, statistics, applied mathematics, or a related field with minimum of 0- years (PhD) or 3-6 years (MSc) of experience working as a pharmacometrician
Good interpersonal and communication skills
Good knowledge and hands-on experience of NONMEM and R
Experience developing PK/PD models to aid in research and development decision making
Knowledge of Health Authority perspective on use of modeling and simulation
Strong English oral and written communication skills
Preferred Qualifications
Good knowledge of pharmacokinetics and pharmacodynamics
Familiar with common techniques used in PK/PD modeling and simulation, like Pheonix NLME, SAS, Monolix, PK-Sim, Simcyp and/or GastroPlus, etc.
Agios Pharmaceuticals
3.8
Agios Pharmaceuticals
