On MedlinePlus Genetics, I'm researching Alpha-1 Antitrypsin Deficiency. Can you tell me what this inherited disorder is, list three common symptoms, explain its genetic cause, and name two related health topics for further reading?
Navigate to the 'Alpha-1 antitrypsin deficiency: MedlinePlus Genetics' page directly. From the 'Description' section, identify what the condition is. From the 'Description' section, list at least three common symptoms. Expand the 'Causes' section. From the 'Causes' section, identify the genetic changes that cause the condition. From the 'Related Health Topics' section, identify at least two related health topics. Synthesize all identified information into a concise answer.
Successfully navigate to the 'Alpha-1 antitrypsin deficiency: MedlinePlus Genetics' page. State that Alpha-1 Antitrypsin Deficiency is an inherited disorder that may cause lung disease and liver disease. List at least three common symptoms of Alpha-1 Antitrypsin Deficiency (e.g., shortness of breath, reduced ability to exercise, wheezing, unintentional weight loss, recurring respiratory infections, fatigue, difficulty breathing, hacking cough, barrel-shaped chest, jaundice, panniculitis). Explain that the condition is caused by mutations in the SERPINA1 gene. Identify at least two related health topics from the page (e.g., Cirrhosis, Emphysema, Genetic Disorders).