"<a href=""https://www.youtube.com/watch?v=Gfr50f6ZBvo&amp;t=1h24m08s"">1:24:08</a>  - why are you sure that the problem of origins of life and how it started on Earth hasn't been solved  yet?  the issues related with physics and chemistry for the  organic life to start here on Earth are quite clear and there are enough theories which have resolved the problem theoretically in general at least. may be we still need to clear up some details and make the experimental tests - then the computer simulations can be really helpful for this.<br><br>the most impressive place of the interview on my taste is at <a href=""https://www.youtube.com/watch?v=Gfr50f6ZBvo&amp;t=1h21m29s"">1:21:29</a> - "it's surprising that more people aren't troubled that all these things we interact with all the time that we have no idea how they work -- time", consciousness, gravity, life  are all the fundamental things of nature but we don't know what they really are..." i'm absolutely agree that these 4 fundamental problems were put together in one set. great!)