To help Demis Hassabis ( @demishassabis ) to once and for all conclusively abandon this at first glance deceivingly positive seeming perspective on humanity expanding into space - as it would be an extremely unethical, criminal trajectory for humanity if it were to happen, though for not at all easily visible reasons (as very many people fall into this blinding love with space colonization) - let me explain why it would be the torturously worst possible of all catastrophies that could ever within all thousands or millions of future years be caused by humans.<br><br>First of all, the ethical importance of an act or decision grows with the number of sentient beings that would be involved in its consequences and the accumulated duration of time for which their experiences would be affected by it. Second of all, based on any ethical axiom along the outlined one, the absolutely most important acts or decisions therefore would be those which determine the long-term fate of habitable celestial bodies, namely for the case of evolution of life to be (accidentally or even intentionally) triggered on them because this involves around the order of magnitude of plausibly billions of species (each with large populations) at any time and throughout billions of years for such celestial body, which are numbers unmatched by any other for life critical event. And third of all, multiple scientific studies demonstrate that for life alike that on earth, suffering generally dominates for wildlife animals - they generally have to endure far worse conditions than farm animals, which many on this issue gravely mistaken people do not realize, due to cognitive dissonance based on their personal experiences that are detached from wildlife conditions in the jungle. So because of this trifecta of facts, and because it will at least foreseeably although likely never at all become possible to have any meaningful control over what will happen to life in general if it were to be ever initiated on extra-terrestrial celestial bodies, because humanity on this pale blue dot will never be able to overpower or just be able to compete with the all-powerful forces of the mighty and ruthless gigantic cosmos, humanity should be more humble about this factual circumstance and absolutely should refrain from forwards-contamimation-risking outer space missions, out of respect and care for what the dire long-term consequences can end up being for all those that may have to endure them otherwise, and this is not negotiable.<br><br>There just is no and there never will be any conceivable ethical subject that matters on a larger scope than natural/directed transpermia or forwards-contamination. Even for the people (and eventually other species reaching our intelligence) that may live thousands or millions of years into our future, this will still be the unique dominantly important highest priority to get right issue and ethical topic. And just because humanity is now starting to be capable of making unnecessarily - in its new space race insanity - clearly rushed decisions in a state of - relative to the future - maximized level of ignorance &amp; lack of experience with respect to this new frontier and thereby could mess up big time with very near future space missions on a never before seen and (hopefully) never afterwards anymore encountered scale, namely by just recklessly risking - for thousands of future human generations to be involuntarily burdened with - irreversible contamination via moon landers on Enceladus (Enceladus Explorer), Europa (Europa Lander), Callisto (Gan De), Ganymede (Laplace-P), this doesn't mean humanity is already in any sufficiently, let alone best informed position to make the right calls on the matter to avoid potential major future harm. To risk violating the in the Outer Space Treaty agreed on, extremely important planetary protection condition that prohibits contamination would be arrogant and respectless towards future generations, since not only would it rob them any opportunity to further scientifically investigate the risks themselves, but it would risk putting them in a position in which those thousands, if not millions of future generations will all have to deal with the severe consequences of by just 1 former generation created outer space contamination. The sterile, pristine integrity of our solar system bodies depends on the metaphorical weakest element in the chain of all outer-space-activities-enabled human generations, and the weakest (least informed, least regulated or unified, ill and eagerly towards egoistic science prizes rushing incentivized) of them all can be expected to be among the very first of possibly thousands more to come.