I don't think we are in a simulation due to the ability to use scanning electron microscopes and other phenomenon. The amount of data required would be insane. The electrons required to "store" each and every experience. The trillions of interactions per millisecond that exist and are measurable would be far too large to store on whatever storage drives one would imagine. We exist as mortal physical being currently. The data would engulf  and be measurable in our observable universe just to fill an earth sized planet. We aren't in a matrix, we could make one but it would be measurable and noticeable due to limitations of physics. Real life which is what we exist in may make a believable digital experience, but it will never achieve the levels of detail in what we experience. It is just far too much data. The storage mechanism would outweigh our universe.