most cases of teleportation do not involve you physically passing through the intervening space. If I wanted to teleport up to the ISS and back down again, I would not need to worry about heat or energy (save if the teleportation somehow used energy). I'd be more worried about the sudden loss of gravity.,(reply>), for a pressure differential it depends on the person. I can cycle open and close my Eustachian tubes at will (no turn my head or hold my nose and blow to equalize pressure). However, the ISS environmental systems are set at one atmosphere and I live at sea level.,(reply>), +metropod Wouldn't the sudden change in pressure also cause its own problems?