Consider the following medical report that includes the patient's historical health records. Use it to predict the disease that the patient is high likely exposed to. 

 Medical Report: allergies: compazine attending: chief complaint: history of stroke, frequent headaches major surgical or invasive procedure: minimally invasive pfo closure history of present illness: mr. is a 45 year old male who suffered a stroke back in . a transesophogeal echocardiogram at that time revealed a patent foramen ovale with right to left flow. additional workup was notable for a prothrombin gene mutation. in preperation for surgical closure, he underwent a coronary cta which ruled out obstructive coronary disease. he presented for surgical intervention. he continues to experience frequent headaches. he was admitted one day prior to surgery for heparinization. past medical history: patent foramen ovale, history of stroke, migraine headaches, hypertension, hyperlipidemia, prothrombin gene mutation, history of syncope, s/p left shoulder surgery, s/p left knee surgery, s/p appendectomy social history: denies tobacco, rare etoh. he is a biology teacher. lives alone. denies recreational and intravenous drug abuse. family history: maternal grandfather died of mi at 40. maternal aunts have autoimmune disorders ie. hashimoto, lupus, rheumatoid arthritis. mother suffered from scleroderma. physical exam: vitals: t 97.3, bp 145/94, hr 62, rr 14, sat 94 on room air general: well developed male in no acute distress heent: oropharynx benign, neck: supple, no jvd, heart: regular rate, normal s1s2, no murmur or rub lungs: clear bilaterally abdomen: soft, nontender, normoactive bowel sounds ext: warm, no edema, no varicosities pulses: 2+ distally neuro: nonfocal pertinent results: 04:15pm blood wbc-5.0 rbc-4.71 hgb-15.4 hct-41.3 mcv-88 mch-32.7* mchc-37.3* rdw-13.6 plt ct-188 04:15pm blood pt-11.7 ptt-24.3 inr(pt)-1.0 04:15pm blood alt-22 ast-15 ld(ldh)-208 alkphos-82 amylase-38 totbili-0.4 brief hospital course: mr. was admitted for heparinization and underwent routine preoperative evaluation. workup was unremarkable and he was cleared for surgery. the following day, dr. performed a minimally invasive closure of his patent foramen. for surgical details, please see seperative dicated operative note. following the operation, he was brought to the csru for invasive monitoring. within 24 hours, he awoke neurologically intact and was extubated without incident. he weaned from intravenous therapy without difficulty. he maintained stable hemodynamics as low beta blockade was resumed. his csru course was uneventful and he transferred to the sdu on postoperative day one. beta blockade was advanced as tolerated and he remained in a normal sinus rhythm. over several days, he continued to make clinical improvements with diuresis. stop medications on admission: warfarin - stopped nadolol discharge disposition: home discharge diagnosis: patent foramen ovale - s/p minimally invasive pfo closure, history of stroke, migraine headaches, hypertension, hyperlipidemia, prothrombin gene mutation discharge condition: good discharge instructions: take medications as directed. monitor wounds for signs of infection. please call with any questions or concerns. please do not drive while taking narcotics. followup instructions: dr. in weeks, call for appt dr. in weeks, call for appt procedure: extracorporeal circulation auxiliary to open heart surgery other and unspecified repair of atrial septal defect diagnoses: pure hypercholesterolemia unspecified essential hypertension ostium secundum type atrial septal defect personal history of other diseases of circulatory system long-term (current) use of anticoagulants 

Answer: The patient is high likely exposed to