Big changes are afoot in Edo in the wake of Shigeshige's funeral and Nobunobu's appointment as shogun.
but all it means is that Lord Nobunobu 
eliminated those who opposed him,
لكن ذلك يعني أن السيد نوبونوبو قد تخلص من الذين عارضوه
pero en realidad eliminó 
a los que le molestaban.
mas só quer dizer que o Lorde Nobunobu
 eliminou todos que se opunham a ele