With the country slowly opening up to foreign influence, the study of rangaku--imported knowledge from the Netherlands--provided by be a source of inspiration that would result in major revolutions in Japanese medicine. And at the center of it all was the medicine-minded cat, Sugita Genpaku!
In the Edo period, the study 
of western science based around
En la Era Edo, los estudios
europeos "rangaku"
Na era Edo, os estudos
científicos do ocidente,