If they do not defeat DIO within 50 days, Holly could die... Jotaro and crew head to Egypt, where they think DIO is hiding. While on the plane, they run into another one of DIO's assassins.
It's now become impossible
 for us to fly to Egypt.
أصبحَ من المُستحيل الآن أن نسافرَ إلى مصر بطائرة
Es ist nun unmöglich für uns,
nach Ägypten zu fliegen.
Nous ne pouvons plus
atteindre l’Égypte en avion.
Ormai è impossibile arrivarci in aereo.
É praticamente impossível 
chegarmos ao Egito de avião.