The number one host in the Kabuki district, Kyoshiro, summons the Odd Jobs members to his club, Takamagahara, and tells them that he intends to quit because of a lady named Madame Yagami who controls the night world.  It seems that she declared she would be making a second visit to Takamagahara, which is essentially a death sentence.  The hosts at Kyoshiro's have quit out of fear, so Gintoki and co must find hosts to handle the Madame...
Sorry, boss.
Lo siento, jefe.
Foi mal, chefia.