The Sket-dan get a new assistant homeroom teacher (who wants everyone to call her, Onee-san), but she's a klutz and is upset she can't be a good role model for the students, so the Sket-dan ask Chuu-san to help with some of his strange drugs. Later, Switch goes through some old inventions of his that didn't work out as intended...
I did research into changing personality 
by controlling the excretions of the brain.
He investigado cómo cambiar la personalidad 
al controlar las secreciones cerebrales.
He investigado cómo cambiar la personalidad 
al controlar las secreciones cerebrales.
Eu fiz uma pesquisa de
 mudança de personalidade